Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for LMX1B_MNX1_RAX2

Z-value: 0.84

Motif logo

logo of logo of logo of

Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
LMX1B
ENSG00000136944.13 LMX1B
MNX1
ENSG00000130675.10 MNX1
RAX2
ENSG00000173976.11 RAX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MNX1hg19_v2_chr7_-_156803329_1568033620.341.9e-01Click!
LMX1Bhg19_v2_chr9_+_129376722_1293767480.175.2e-01Click!
RAX2hg19_v2_chr19_-_3772209_37722360.097.4e-01Click!

Activity profile of LMX1B_MNX1_RAX2 motif

Sorted Z-values of LMX1B_MNX1_RAX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_169418195 4.78 ENST00000261509.6
ENST00000335742.7
 PALLD
 palladin, cytoskeletal associated protein
chr12_-_28123206 3.38 ENST00000542963.1
ENST00000535992.1
 PTHLH
 parathyroid hormone-like hormone
chr17_-_64225508 3.08 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr12_-_28122980 2.87 ENST00000395868.3
ENST00000534890.1
 PTHLH
 parathyroid hormone-like hormone
chr12_-_52967600 2.79 ENST00000549343.1
ENST00000305620.2
 KRT74
 keratin 74
chr7_+_134464414 2.36 ENST00000361901.2
 CALD1
 caldesmon 1
chr4_+_169418255 2.27 ENST00000505667.1
ENST00000511948.1
 PALLD
 palladin, cytoskeletal associated protein
chr3_-_151034734 2.21 ENST00000260843.4
 GPR87
 G protein-coupled receptor 87
chr11_-_129062093 1.97 ENST00000310343.9
 ARHGAP32
 Rho GTPase activating protein 32
chr7_+_134464376 1.91 ENST00000454108.1
ENST00000361675.2
 CALD1
 caldesmon 1
chr12_-_89746173 1.86 ENST00000308385.6
 DUSP6
 dual specificity phosphatase 6
chr1_-_237167718 1.80 ENST00000464121.2
 MT1HL1
 metallothionein 1H-like 1
chrX_-_13835147 1.61 ENST00000493677.1
ENST00000355135.2
 GPM6B
 glycoprotein M6B
chr7_-_107642348 1.60 ENST00000393561.1
 LAMB1
 laminin, beta 1
chr16_-_29910853 1.50 ENST00000308713.5
 SEZ6L2
 seizure related 6 homolog (mouse)-like 2
chrX_+_105937068 1.38 ENST00000324342.3
 RNF128
 ring finger protein 128, E3 ubiquitin protein ligase
chr19_-_51522955 1.26 ENST00000358789.3
 KLK10
 kallikrein-related peptidase 10
chrX_-_106243451 1.18 ENST00000355610.4
ENST00000535534.1
 MORC4
 MORC family CW-type zinc finger 4
chr2_+_68961934 1.11 ENST00000409202.3
 ARHGAP25
 Rho GTPase activating protein 25
chr2_+_68961905 1.10 ENST00000295381.3
 ARHGAP25
 Rho GTPase activating protein 25
chr7_-_27169801 1.09 ENST00000511914.1
 HOXA4
 homeobox A4
chr3_-_79816965 0.97 ENST00000464233.1
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_+_66300446 0.95 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr4_-_143226979 0.88 ENST00000514525.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr5_+_174151536 0.86 ENST00000239243.6
ENST00000507785.1
 MSX2
 msh homeobox 2
chr17_-_77924627 0.83 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
 TBC1D16
 TBC1 domain family, member 16
chrX_-_10851762 0.80 ENST00000380785.1
ENST00000380787.1
 MID1
 midline 1 (Opitz/BBB syndrome)
chr4_-_143227088 0.79 ENST00000511838.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr18_+_29027696 0.70 ENST00000257189.4
 DSG3
 desmoglein 3
chr17_+_72427477 0.67 ENST00000342648.5
ENST00000481232.1
 GPRC5C
 G protein-coupled receptor, family C, group 5, member C
chr5_-_1882858 0.64 ENST00000511126.1
ENST00000231357.2
 IRX4
 iroquois homeobox 4
chr7_-_87342564 0.63 ENST00000265724.3
ENST00000416177.1
 ABCB1
 ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr20_+_30697298 0.63 ENST00000398022.2
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr3_+_111717600 0.62 ENST00000273368.4
 TAGLN3
 transgelin 3
chr2_+_187454749 0.61 ENST00000261023.3
ENST00000374907.3
 ITGAV
 integrin, alpha V
chr1_+_68150744 0.60 ENST00000370986.4
ENST00000370985.3
 GADD45A
 growth arrest and DNA-damage-inducible, alpha
chr2_+_68962014 0.59 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr8_-_18744528 0.58 ENST00000523619.1
 PSD3
 pleckstrin and Sec7 domain containing 3
chr3_+_111718036 0.56 ENST00000455401.2
 TAGLN3
 transgelin 3
chr12_+_81110684 0.55 ENST00000228644.3
 MYF5
 myogenic factor 5
chr8_+_105235572 0.53 ENST00000523362.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chr2_+_234826016 0.52 ENST00000324695.4
ENST00000433712.2
 TRPM8
 transient receptor potential cation channel, subfamily M, member 8
chr17_+_47448102 0.51 ENST00000576461.1
 RP11-81K2.1
 Uncharacterized protein
chr2_-_208031943 0.51 ENST00000421199.1
ENST00000457962.1
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chr3_-_149293990 0.49 ENST00000472417.1
 WWTR1
 WW domain containing transcription regulator 1
chr8_+_101170563 0.49 ENST00000520508.1
ENST00000388798.2
 SPAG1
 sperm associated antigen 1
chr3_+_111717511 0.48 ENST00000478951.1
ENST00000393917.2
 TAGLN3
 transgelin 3
chr1_+_225600404 0.47 ENST00000366845.2
 AC092811.1
 AC092811.1
chr4_-_186696425 0.46 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2
 sorbin and SH3 domain containing 2
chr15_+_58702742 0.46 ENST00000356113.6
ENST00000414170.3
 LIPC
 lipase, hepatic
chr14_+_21156915 0.45 ENST00000397990.4
ENST00000555597.1
 ANG
RNASE4
 angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr1_-_227505289 0.43 ENST00000366765.3
 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
chr19_-_51523412 0.42 ENST00000391805.1
ENST00000599077.1
 KLK10
 kallikrein-related peptidase 10
chr5_+_125758865 0.42 ENST00000542322.1
ENST00000544396.1
 GRAMD3
 GRAM domain containing 3
chr19_-_51523275 0.42 ENST00000309958.3
 KLK10
 kallikrein-related peptidase 10
chr2_-_207024233 0.41 ENST00000423725.1
ENST00000233190.6
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr5_+_125758813 0.39 ENST00000285689.3
ENST00000515200.1
 GRAMD3
 GRAM domain containing 3
chr1_-_24469602 0.38 ENST00000270800.1
 IL22RA1
 interleukin 22 receptor, alpha 1
chr6_-_87804815 0.38 ENST00000369582.2
 CGA
 glycoprotein hormones, alpha polypeptide
chr19_+_50016610 0.37 ENST00000596975.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr1_-_68698222 0.35 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
 WLS
 wntless Wnt ligand secretion mediator
chr1_+_180601139 0.32 ENST00000367590.4
ENST00000367589.3
 XPR1
 xenotropic and polytropic retrovirus receptor 1
chr3_+_111718173 0.32 ENST00000494932.1
 TAGLN3
 transgelin 3
chr3_+_158787041 0.31 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
chr6_+_151646800 0.31 ENST00000354675.6
 AKAP12
 A kinase (PRKA) anchor protein 12
chr19_+_50016411 0.30 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr17_-_39191107 0.30 ENST00000344363.5
 KRTAP1-3
 keratin associated protein 1-3
chr1_-_94586651 0.30 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr18_-_33709268 0.29 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
 SLC39A6
 solute carrier family 39 (zinc transporter), member 6
chr1_+_214161272 0.29 ENST00000498508.2
ENST00000366958.4
 PROX1
 prospero homeobox 1
chr16_-_4852915 0.29 ENST00000322048.7
 ROGDI
 rogdi homolog (Drosophila)
chr3_-_178984759 0.29 ENST00000349697.2
ENST00000497599.1
 KCNMB3
 potassium large conductance calcium-activated channel, subfamily M beta member 3
chr7_-_22234381 0.29 ENST00000458533.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr14_-_38064198 0.29 ENST00000250448.2
 FOXA1
 forkhead box A1
chr1_+_214161854 0.28 ENST00000435016.1
 PROX1
 prospero homeobox 1
chr16_+_69345243 0.27 ENST00000254950.11
 VPS4A
 vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr17_+_41363854 0.26 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
 TMEM106A
 transmembrane protein 106A
chr7_+_100136811 0.24 ENST00000300176.4
ENST00000262935.4
 AGFG2
 ArfGAP with FG repeats 2
chr2_+_109237717 0.23 ENST00000409441.1
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr14_+_104182061 0.23 ENST00000216602.6
 ZFYVE21
 zinc finger, FYVE domain containing 21
chr7_-_107443652 0.22 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
 SLC26A3
 solute carrier family 26 (anion exchanger), member 3
chr2_-_216946500 0.22 ENST00000265322.7
 PECR
 peroxisomal trans-2-enoyl-CoA reductase
chr14_+_104182105 0.21 ENST00000311141.2
 ZFYVE21
 zinc finger, FYVE domain containing 21
chr7_-_143599207 0.19 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
 FAM115A
 family with sequence similarity 115, member A
chr15_+_93443419 0.18 ENST00000557381.1
ENST00000420239.2
 CHD2
 chromodomain helicase DNA binding protein 2
chr2_-_74619152 0.18 ENST00000440727.1
ENST00000409240.1
 DCTN1
 dynactin 1
chrX_+_78003204 0.18 ENST00000435339.3
ENST00000514744.1
 LPAR4
 lysophosphatidic acid receptor 4
chr2_-_207024134 0.18 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr18_+_46065393 0.18 ENST00000256413.3
 CTIF
 CBP80/20-dependent translation initiation factor
chr1_+_210501589 0.18 ENST00000413764.2
ENST00000541565.1
 HHAT
 hedgehog acyltransferase
chr12_-_10978957 0.17 ENST00000240619.2
 TAS2R10
 taste receptor, type 2, member 10
chr6_-_136788001 0.17 ENST00000544465.1
 MAP7
 microtubule-associated protein 7
chr2_+_171034646 0.15 ENST00000409044.3
ENST00000408978.4
 MYO3B
 myosin IIIB
chr3_+_130569429 0.15 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr1_-_92952433 0.14 ENST00000294702.5
 GFI1
 growth factor independent 1 transcription repressor
chr4_+_69313145 0.14 ENST00000305363.4
 TMPRSS11E
 transmembrane protease, serine 11E
chr6_-_111927449 0.14 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
 TRAF3IP2
 TRAF3 interacting protein 2
chr7_+_138145076 0.14 ENST00000343526.4
 TRIM24
 tripartite motif containing 24
chr4_+_175204818 0.14 ENST00000503780.1
 CEP44
 centrosomal protein 44kDa
chr17_-_72772462 0.14 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
 NAT9
 N-acetyltransferase 9 (GCN5-related, putative)
chr11_+_63606373 0.13 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
 MARK2
 MAP/microtubule affinity-regulating kinase 2
chr1_+_117544366 0.13 ENST00000256652.4
ENST00000369470.1
 CD101
 CD101 molecule
chr7_-_83278322 0.13 ENST00000307792.3
 SEMA3E
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr7_-_44580861 0.13 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
 NPC1L1
 NPC1-like 1
chr5_-_24645078 0.13 ENST00000264463.4
 CDH10
 cadherin 10, type 2 (T2-cadherin)
chr4_+_3388057 0.13 ENST00000538395.1
 RGS12
 regulator of G-protein signaling 12
chr19_-_5903714 0.13 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
 AC024592.12
NDUFA11
FUT5
 Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr16_+_68279207 0.13 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
 PLA2G15
 phospholipase A2, group XV
chr2_+_170440844 0.12 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
 PPIG
 peptidylprolyl isomerase G (cyclophilin G)
chr14_-_25479811 0.12 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr4_+_71457970 0.11 ENST00000322937.6
 AMBN
 ameloblastin (enamel matrix protein)
chr12_+_26348582 0.11 ENST00000535504.1
 SSPN
 sarcospan
chr4_+_88754113 0.11 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
 MEPE
 matrix extracellular phosphoglycoprotein
chr1_-_242162375 0.11 ENST00000357246.3
 MAP1LC3C
 microtubule-associated protein 1 light chain 3 gamma
chr2_-_207023918 0.11 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_+_177015122 0.11 ENST00000468418.3
 HOXD3
 homeobox D3
chr19_-_14064114 0.11 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
 PODNL1
 podocan-like 1
chr19_-_46088068 0.11 ENST00000263275.4
ENST00000323060.3
 OPA3
 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr1_-_68698197 0.10 ENST00000370973.2
ENST00000370971.1
 WLS
 wntless Wnt ligand secretion mediator
chr3_-_52090461 0.10 ENST00000296483.6
ENST00000495880.1
 DUSP7
 dual specificity phosphatase 7
chr19_-_36304201 0.10 ENST00000301175.3
 PRODH2
 proline dehydrogenase (oxidase) 2
chr12_-_118796910 0.10 ENST00000541186.1
ENST00000539872.1
 TAOK3
 TAO kinase 3
chr4_+_41614720 0.10 ENST00000509277.1
 LIMCH1
 LIM and calponin homology domains 1
chr11_+_92702886 0.10 ENST00000257068.2
ENST00000528076.1
 MTNR1B
 melatonin receptor 1B
chr14_+_32798547 0.10 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
 AKAP6
 A kinase (PRKA) anchor protein 6
chr17_-_39646116 0.10 ENST00000328119.6
 KRT36
 keratin 36
chr13_+_53602894 0.10 ENST00000219022.2
 OLFM4
 olfactomedin 4
chr4_+_71458012 0.10 ENST00000449493.2
 AMBN
 ameloblastin (enamel matrix protein)
chr1_+_62439037 0.10 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr6_-_136847099 0.09 ENST00000438100.2
 MAP7
 microtubule-associated protein 7
chr19_+_13049413 0.09 ENST00000316448.5
ENST00000588454.1
 CALR
 calreticulin
chr16_+_57279004 0.09 ENST00000219204.3
 ARL2BP
 ADP-ribosylation factor-like 2 binding protein
chr13_-_44735393 0.09 ENST00000400419.1
 SMIM2
 small integral membrane protein 2
chr20_-_21494654 0.09 ENST00000377142.4
 NKX2-2
 NK2 homeobox 2
chr13_-_95131923 0.09 ENST00000377028.5
ENST00000446125.1
 DCT
 dopachrome tautomerase
chr2_+_45168875 0.09 ENST00000260653.3
 SIX3
 SIX homeobox 3
chr1_+_154401791 0.09 ENST00000476006.1
 IL6R
 interleukin 6 receptor
chr12_+_4385230 0.09 ENST00000536537.1
 CCND2
 cyclin D2
chr2_-_190927447 0.08 ENST00000260950.4
 MSTN
 myostatin
chr3_-_157824292 0.08 ENST00000483851.2
 SHOX2
 short stature homeobox 2
chr4_-_139163491 0.08 ENST00000280612.5
 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr17_-_38859996 0.08 ENST00000264651.2
 KRT24
 keratin 24
chrX_-_18690210 0.08 ENST00000379984.3
 RS1
 retinoschisin 1
chr4_+_88754069 0.08 ENST00000395102.4
ENST00000497649.2
 MEPE
 matrix extracellular phosphoglycoprotein
chrX_+_135730297 0.08 ENST00000370629.2
 CD40LG
 CD40 ligand
chrX_+_144908928 0.08 ENST00000408967.2
 TMEM257
 transmembrane protein 257
chr8_+_117950422 0.07 ENST00000378279.3
 AARD
 alanine and arginine rich domain containing protein
chr13_-_36050819 0.07 ENST00000379919.4
 MAB21L1
 mab-21-like 1 (C. elegans)
chr12_-_16759711 0.07 ENST00000447609.1
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr14_+_72052983 0.07 ENST00000358550.2
 SIPA1L1
 signal-induced proliferation-associated 1 like 1
chr12_+_41831485 0.07 ENST00000539469.2
ENST00000298919.7
 PDZRN4
 PDZ domain containing ring finger 4
chr1_+_50569575 0.07 ENST00000371827.1
 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
chr12_-_53994805 0.07 ENST00000328463.7
 ATF7
 activating transcription factor 7
chr3_-_114477787 0.07 ENST00000464560.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr12_-_86650045 0.06 ENST00000604798.1
 MGAT4C
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chrX_-_19988382 0.06 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
 CXorf23
 chromosome X open reading frame 23
chr9_-_136933134 0.06 ENST00000303407.7
 BRD3
 bromodomain containing 3
chrX_+_107288239 0.06 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr8_-_25281747 0.06 ENST00000421054.2
 GNRH1
 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr14_-_78083112 0.06 ENST00000216484.2
 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
chr10_+_102222798 0.06 ENST00000343737.5
 WNT8B
 wingless-type MMTV integration site family, member 8B
chr15_+_44092784 0.06 ENST00000458412.1
 HYPK
 huntingtin interacting protein K
chr6_-_31107127 0.06 ENST00000259845.4
 PSORS1C2
 psoriasis susceptibility 1 candidate 2
chr3_-_167191814 0.06 ENST00000466903.1
ENST00000264677.4
 SERPINI2
 serpin peptidase inhibitor, clade I (pancpin), member 2
chr16_+_89334512 0.06 ENST00000602042.1
 AC137932.1
 AC137932.1
chr8_-_93107696 0.05 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_122688090 0.05 ENST00000324189.4
ENST00000546192.1
 B3GNT4
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr2_-_100987007 0.05 ENST00000595083.1
 AC012493.2
 Uncharacterized protein
chr22_-_40929812 0.05 ENST00000422851.1
 MKL1
 megakaryoblastic leukemia (translocation) 1
chr12_-_86650077 0.05 ENST00000552808.2
ENST00000547225.1
 MGAT4C
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr10_+_26505179 0.05 ENST00000376261.3
 GAD2
 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr9_+_82188077 0.05 ENST00000425506.1
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_48937821 0.05 ENST00000396199.3
 SPATA6
 spermatogenesis associated 6
chr16_+_30669720 0.05 ENST00000356166.6
 FBRS
 fibrosin
chr4_+_88571429 0.05 ENST00000339673.6
ENST00000282479.7
 DMP1
 dentin matrix acidic phosphoprotein 1
chr6_-_167797887 0.05 ENST00000476779.2
ENST00000460930.2
ENST00000397829.4
ENST00000366827.2
 TCP10
 t-complex 10
chr2_+_207024306 0.05 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
 EEF1B2
 eukaryotic translation elongation factor 1 beta 2
chrX_+_135730373 0.04 ENST00000370628.2
 CD40LG
 CD40 ligand
chr21_-_31538971 0.04 ENST00000286808.3
 CLDN17
 claudin 17
chr14_+_32798462 0.04 ENST00000280979.4
 AKAP6
 A kinase (PRKA) anchor protein 6
chr17_-_56296580 0.04 ENST00000313863.6
ENST00000546108.1
ENST00000337050.7
ENST00000393119.2
 MKS1
 Meckel syndrome, type 1
chr1_-_149900122 0.04 ENST00000271628.8
 SF3B4
 splicing factor 3b, subunit 4, 49kDa
chr12_-_53171128 0.04 ENST00000332411.2
 KRT76
 keratin 76
chr4_+_41614909 0.03 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
 LIMCH1
 LIM and calponin homology domains 1
chr10_-_96829246 0.03 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
 CYP2C8
 cytochrome P450, family 2, subfamily C, polypeptide 8
chr1_-_48937838 0.03 ENST00000371847.3
 SPATA6
 spermatogenesis associated 6
chr6_+_153071925 0.03 ENST00000367244.3
ENST00000367243.3
 VIP
 vasoactive intestinal peptide
chr5_-_138534071 0.03 ENST00000394817.2
 SIL1
 SIL1 nucleotide exchange factor
chr3_+_155838337 0.03 ENST00000490337.1
ENST00000389636.5
 KCNAB1
 potassium voltage-gated channel, shaker-related subfamily, beta member 1
chrX_+_22050546 0.03 ENST00000379374.4
 PHEX
 phosphate regulating endopeptidase homolog, X-linked
chr1_-_151762943 0.03 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
 TDRKH
 tudor and KH domain containing
chr19_+_4402659 0.03 ENST00000301280.5
ENST00000585854.1
 CHAF1A
 chromatin assembly factor 1, subunit A (p150)
chr2_-_209010874 0.03 ENST00000260988.4
 CRYGB
 crystallin, gamma B
chr1_-_204135450 0.03 ENST00000272190.8
ENST00000367195.2
 REN
 renin
chr13_-_88323218 0.02 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
 MIR4500HG
 MIR4500 host gene (non-protein coding)
chr12_-_10955226 0.02 ENST00000240687.2
 TAS2R7
 taste receptor, type 2, member 7
chr4_+_88529681 0.02 ENST00000399271.1
 DSPP
 dentin sialophosphoprotein
chr8_-_42234745 0.02 ENST00000220812.2
 DKK4
 dickkopf WNT signaling pathway inhibitor 4
chr6_-_136847610 0.02 ENST00000454590.1
ENST00000432797.2
 MAP7
 microtubule-associated protein 7
chr10_-_115904361 0.02 ENST00000428953.1
ENST00000543782.1
 C10orf118
 chromosome 10 open reading frame 118

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.4 1.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 1.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.3 7.1 GO:0003334 keratinocyte development(GO:0003334)
0.3 0.9 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.3 3.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 6.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 0.6 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 1.6 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.6 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.2 1.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.6 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 2.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 0.7 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 2.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.5 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.6 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.6 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.6 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 1.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.7 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.3 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0051799 negative regulation of hair follicle development(GO:0051799)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 4.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 6.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 2.8 GO:1990254 keratin filament binding(GO:1990254)
0.3 1.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3 6.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 6.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 4.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.6 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 2.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 5.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005607 laminin-2 complex(GO:0005607)
0.3 4.3 GO:0030478 actin cap(GO:0030478)
0.2 0.6 GO:0034685 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.2 3.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 4.9 GO:0002102 podosome(GO:0002102)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 2.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)