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ENCODE cell lines, expression (Ernst 2011)

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Results for MBD2

Z-value: 1.51

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
MBD2
ENSG00000134046.7 MBD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg19_v2_chr18_-_51751132_51751158-0.448.6e-02Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_9346892 4.47 ENST00000281419.3
ENST00000315273.4
 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr1_+_99127225 4.12 ENST00000370189.5
ENST00000529992.1
 SNX7
 sorting nexin 7
chr2_+_173292390 4.03 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
 ITGA6
 integrin, alpha 6
chr1_+_99127265 4.02 ENST00000306121.3
 SNX7
 sorting nexin 7
chr3_-_185542761 3.73 ENST00000457616.2
ENST00000346192.3
 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
chr3_-_185542817 3.53 ENST00000382199.2
 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
chr3_-_149688896 3.23 ENST00000239940.7
 PFN2
 profilin 2
chr3_-_149688502 3.17 ENST00000481767.1
ENST00000475518.1
 PFN2
 profilin 2
chr13_+_27131798 2.94 ENST00000361042.4
 WASF3
 WAS protein family, member 3
chr10_-_17659234 2.90 ENST00000466335.1
 PTPLA
 protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr13_+_27131887 2.80 ENST00000335327.5
 WASF3
 WAS protein family, member 3
chr11_-_2160180 2.73 ENST00000381406.4
 IGF2
 insulin-like growth factor 2 (somatomedin A)
chr2_+_173292301 2.64 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
 ITGA6
 integrin, alpha 6
chr11_-_2160611 2.62 ENST00000416167.2
 IGF2
 insulin-like growth factor 2 (somatomedin A)
chr8_+_30241934 2.43 ENST00000538486.1
 RBPMS
 RNA binding protein with multiple splicing
chr9_-_74383799 2.39 ENST00000377044.4
 TMEM2
 transmembrane protein 2
chr11_+_69455855 2.22 ENST00000227507.2
ENST00000536559.1
 CCND1
 cyclin D1
chr13_+_98795434 2.19 ENST00000376586.2
 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr13_+_98795505 2.17 ENST00000319562.6
 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr10_-_17659357 2.10 ENST00000326961.6
ENST00000361271.3
 PTPLA
 protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr8_+_30241995 2.06 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
 RBPMS
 RNA binding protein with multiple splicing
chr12_-_124457257 2.01 ENST00000545891.1
 CCDC92
 coiled-coil domain containing 92
chr13_-_80915059 1.94 ENST00000377104.3
 SPRY2
 sprouty homolog 2 (Drosophila)
chr14_+_21538429 1.94 ENST00000298694.4
ENST00000555038.1
 ARHGEF40
 Rho guanine nucleotide exchange factor (GEF) 40
chr11_-_75236867 1.93 ENST00000376282.3
ENST00000336898.3
 GDPD5
 glycerophosphodiester phosphodiesterase domain containing 5
chr2_+_236402669 1.93 ENST00000409457.1
ENST00000336665.5
ENST00000304032.8
 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr14_+_21538517 1.91 ENST00000298693.3
 ARHGEF40
 Rho guanine nucleotide exchange factor (GEF) 40
chr6_+_107811162 1.74 ENST00000317357.5
 SOBP
 sine oculis binding protein homolog (Drosophila)
chr12_+_19282643 1.71 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
 PLEKHA5
 pleckstrin homology domain containing, family A member 5
chr18_-_812517 1.69 ENST00000584307.1
 YES1
 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr16_-_22385901 1.64 ENST00000268383.2
 CDR2
 cerebellar degeneration-related protein 2, 62kDa
chr17_+_19552036 1.63 ENST00000581518.1
ENST00000395575.2
ENST00000584332.2
ENST00000339618.4
ENST00000579855.1
 ALDH3A2
 aldehyde dehydrogenase 3 family, member A2
chr3_-_124774802 1.61 ENST00000311127.4
 HEG1
 heart development protein with EGF-like domains 1
chr18_-_812231 1.58 ENST00000314574.4
 YES1
 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr19_+_18496957 1.56 ENST00000252809.3
 GDF15
 growth differentiation factor 15
chr12_-_124457371 1.54 ENST00000238156.3
ENST00000545037.1
 CCDC92
 coiled-coil domain containing 92
chr10_+_104404218 1.51 ENST00000302424.7
 TRIM8
 tripartite motif containing 8
chr3_+_33155525 1.51 ENST00000449224.1
 CRTAP
 cartilage associated protein
chr6_+_31865552 1.50 ENST00000469372.1
ENST00000497706.1
 C2
 complement component 2
chr19_-_19051103 1.45 ENST00000542541.2
ENST00000433218.2
 HOMER3
 homer homolog 3 (Drosophila)
chr17_-_27278304 1.43 ENST00000577226.1
 PHF12
 PHD finger protein 12
chr10_-_79686284 1.43 ENST00000372391.2
ENST00000372388.2
 DLG5
 discs, large homolog 5 (Drosophila)
chr1_+_82266053 1.43 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
 LPHN2
 latrophilin 2
chr16_-_4166186 1.41 ENST00000294016.3
 ADCY9
 adenylate cyclase 9
chr19_-_11373128 1.40 ENST00000294618.7
 DOCK6
 dedicator of cytokinesis 6
chr17_-_62658186 1.39 ENST00000262435.9
 SMURF2
 SMAD specific E3 ubiquitin protein ligase 2
chr14_-_103523745 1.38 ENST00000361246.2
 CDC42BPB
 CDC42 binding protein kinase beta (DMPK-like)
chr12_-_115121962 1.37 ENST00000349155.2
 TBX3
 T-box 3
chr12_-_44200146 1.35 ENST00000395510.2
ENST00000325127.4
 TWF1
 twinfilin actin-binding protein 1
chr10_+_129845823 1.34 ENST00000306042.5
 PTPRE
 protein tyrosine phosphatase, receptor type, E
chr6_+_148663729 1.34 ENST00000367467.3
 SASH1
 SAM and SH3 domain containing 1
chr5_-_39425290 1.33 ENST00000545653.1
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr1_-_43232649 1.27 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
 LEPRE1
 leucine proline-enriched proteoglycan (leprecan) 1
chr19_-_36643329 1.24 ENST00000589154.1
 COX7A1
 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr21_-_27542972 1.23 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
 APP
 amyloid beta (A4) precursor protein
chr7_+_94285637 1.19 ENST00000482108.1
ENST00000488574.1
 PEG10
 paternally expressed 10
chr5_-_127873659 1.16 ENST00000262464.4
 FBN2
 fibrillin 2
chr3_+_33155444 1.15 ENST00000320954.6
 CRTAP
 cartilage associated protein
chr12_-_44200052 1.14 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
 TWF1
 twinfilin actin-binding protein 1
chr9_-_136933134 1.11 ENST00000303407.7
 BRD3
 bromodomain containing 3
chr7_+_40174565 1.08 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
 C7orf10
 succinylCoA:glutarate-CoA transferase
chr19_+_36606654 1.07 ENST00000588385.1
ENST00000585746.1
 TBCB
 tubulin folding cofactor B
chr20_-_47804894 1.05 ENST00000371828.3
ENST00000371856.2
ENST00000360426.4
ENST00000347458.5
ENST00000340954.7
ENST00000371802.1
ENST00000371792.1
ENST00000437404.2
 STAU1
 staufen double-stranded RNA binding protein 1
chr7_-_94285402 1.03 ENST00000428696.2
ENST00000445866.2
 SGCE
 sarcoglycan, epsilon
chr11_-_115375107 1.03 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1
 cell adhesion molecule 1
chr5_-_176900610 1.03 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
 DBN1
 drebrin 1
chr2_-_11484710 1.00 ENST00000315872.6
 ROCK2
 Rho-associated, coiled-coil containing protein kinase 2
chr17_+_48133459 0.98 ENST00000320031.8
 ITGA3
 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr10_+_128593978 0.98 ENST00000280333.6
 DOCK1
 dedicator of cytokinesis 1
chr7_-_94285472 0.97 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
 SGCE
 sarcoglycan, epsilon
chr1_-_9884011 0.96 ENST00000361311.4
 CLSTN1
 calsyntenin 1
chr19_+_36606354 0.95 ENST00000589996.1
ENST00000591296.1
 TBCB
 tubulin folding cofactor B
chr2_+_241375069 0.95 ENST00000264039.2
 GPC1
 glypican 1
chr2_+_110551851 0.94 ENST00000272454.6
ENST00000430736.1
ENST00000016946.3
ENST00000441344.1
 RGPD5
 RANBP2-like and GRIP domain containing 5
chr18_-_51750948 0.94 ENST00000583046.1
ENST00000398398.2
 MBD2
 methyl-CpG binding domain protein 2
chr7_-_94285511 0.92 ENST00000265735.7
 SGCE
 sarcoglycan, epsilon
chr12_+_120972147 0.90 ENST00000325954.4
ENST00000542438.1
 RNF10
 ring finger protein 10
chr11_-_76381781 0.89 ENST00000260061.5
ENST00000404995.1
 LRRC32
 leucine rich repeat containing 32
chr5_+_14143728 0.88 ENST00000344204.4
ENST00000537187.1
 TRIO
 trio Rho guanine nucleotide exchange factor
chr3_-_133969437 0.88 ENST00000460933.1
ENST00000296084.4
 RYK
 receptor-like tyrosine kinase
chr19_+_56152262 0.86 ENST00000325333.5
ENST00000590190.1
 ZNF580
 zinc finger protein 580
chr19_+_36606933 0.84 ENST00000586868.1
 TBCB
 tubulin folding cofactor B
chr14_-_89883412 0.84 ENST00000557258.1
 FOXN3
 forkhead box N3
chr22_-_50746027 0.83 ENST00000425954.1
ENST00000449103.1
 PLXNB2
 plexin B2
chr17_+_46126135 0.82 ENST00000361665.3
ENST00000585062.1
 NFE2L1
 nuclear factor, erythroid 2-like 1
chr6_+_139456226 0.81 ENST00000367658.2
 HECA
 headcase homolog (Drosophila)
chr19_-_1568057 0.80 ENST00000402693.4
ENST00000388824.6
 MEX3D
 mex-3 RNA binding family member D
chrX_-_134049262 0.80 ENST00000370783.3
 MOSPD1
 motile sperm domain containing 1
chr8_-_119124045 0.78 ENST00000378204.2
 EXT1
 exostosin glycosyltransferase 1
chr18_+_56530794 0.78 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
 ZNF532
 zinc finger protein 532
chr14_+_102829300 0.77 ENST00000359520.7
 TECPR2
 tectonin beta-propeller repeat containing 2
chr12_+_19282713 0.76 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
 PLEKHA5
 pleckstrin homology domain containing, family A member 5
chr8_+_37654693 0.75 ENST00000412232.2
 GPR124
 G protein-coupled receptor 124
chr9_-_130617029 0.74 ENST00000373203.4
 ENG
 endoglin
chr22_-_50746001 0.73 ENST00000359337.4
 PLXNB2
 plexin B2
chr11_-_89224508 0.73 ENST00000525196.1
 NOX4
 NADPH oxidase 4
chr17_+_46125707 0.73 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
 NFE2L1
 nuclear factor, erythroid 2-like 1
chr12_-_48398104 0.72 ENST00000337299.6
ENST00000380518.3
 COL2A1
 collagen, type II, alpha 1
chr11_-_89224488 0.71 ENST00000534731.1
ENST00000527626.1
 NOX4
 NADPH oxidase 4
chr20_-_56284816 0.71 ENST00000395819.3
ENST00000341744.3
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chr17_-_80231557 0.71 ENST00000392334.2
ENST00000314028.6
 CSNK1D
 casein kinase 1, delta
chr3_-_133969673 0.70 ENST00000427044.2
 RYK
 receptor-like tyrosine kinase
chr17_-_41623075 0.70 ENST00000545089.1
 ETV4
 ets variant 4
chr3_-_38691119 0.70 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
 SCN5A
 sodium channel, voltage-gated, type V, alpha subunit
chr3_-_98620500 0.69 ENST00000326840.6
 DCBLD2
 discoidin, CUB and LCCL domain containing 2
chr11_-_89224299 0.67 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
 NOX4
 NADPH oxidase 4
chr10_+_75545391 0.67 ENST00000604524.1
ENST00000605216.1
ENST00000398706.2
 ZSWIM8
 zinc finger, SWIM-type containing 8
chr7_-_558876 0.65 ENST00000354513.5
ENST00000402802.3
 PDGFA
 platelet-derived growth factor alpha polypeptide
chr1_+_19923454 0.65 ENST00000602662.1
ENST00000602293.1
ENST00000322753.6
 MINOS1-NBL1
MINOS1
 MINOS1-NBL1 readthrough
mitochondrial inner membrane organizing system 1
chr17_+_68165657 0.65 ENST00000243457.3
 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
chr11_-_62369291 0.65 ENST00000278823.2
 MTA2
 metastasis associated 1 family, member 2
chr2_+_54198210 0.64 ENST00000607452.1
ENST00000422521.2
 ACYP2
 acylphosphatase 2, muscle type
chr3_-_52001448 0.63 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
 PCBP4
 poly(rC) binding protein 4
chr1_+_84543734 0.63 ENST00000370689.2
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr9_-_130616915 0.62 ENST00000344849.3
 ENG
 endoglin
chr15_-_73925651 0.61 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
 NPTN
 neuroplastin
chr11_-_89224638 0.61 ENST00000535633.1
ENST00000263317.4
 NOX4
 NADPH oxidase 4
chr11_+_43380459 0.60 ENST00000299240.6
ENST00000039989.4
 TTC17
 tetratricopeptide repeat domain 17
chrX_+_9983602 0.60 ENST00000380861.4
 WWC3
 WWC family member 3
chr17_-_41623259 0.58 ENST00000538265.1
ENST00000591713.1
 ETV4
 ets variant 4
chr10_+_75545329 0.58 ENST00000604729.1
ENST00000603114.1
 ZSWIM8
 zinc finger, SWIM-type containing 8
chr14_+_74416989 0.57 ENST00000334571.2
ENST00000554920.1
 COQ6
 coenzyme Q6 monooxygenase
chr17_-_42277203 0.57 ENST00000587097.1
 ATXN7L3
 ataxin 7-like 3
chr1_+_156698234 0.57 ENST00000368218.4
ENST00000368216.4
 RRNAD1
 ribosomal RNA adenine dimethylase domain containing 1
chr12_-_57824739 0.57 ENST00000347140.3
ENST00000402412.1
 R3HDM2
 R3H domain containing 2
chr8_-_145688231 0.56 ENST00000530374.1
 CYHR1
 cysteine/histidine-rich 1
chr1_+_43855560 0.56 ENST00000562955.1
 SZT2
 seizure threshold 2 homolog (mouse)
chrX_+_152953505 0.55 ENST00000253122.5
 SLC6A8
 solute carrier family 6 (neurotransmitter transporter), member 8
chr17_-_80231300 0.53 ENST00000398519.5
ENST00000580446.1
 CSNK1D
 casein kinase 1, delta
chr3_+_197518100 0.53 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
 LRCH3
 leucine-rich repeats and calponin homology (CH) domain containing 3
chr2_+_5832799 0.52 ENST00000322002.3
 SOX11
 SRY (sex determining region Y)-box 11
chr11_-_89224139 0.51 ENST00000413594.2
 NOX4
 NADPH oxidase 4
chr2_-_178257401 0.51 ENST00000464747.1
 NFE2L2
 nuclear factor, erythroid 2-like 2
chr6_+_1610681 0.50 ENST00000380874.2
 FOXC1
 forkhead box C1
chr9_+_103235365 0.50 ENST00000374879.4
 TMEFF1
 transmembrane protein with EGF-like and two follistatin-like domains 1
chr3_+_142442841 0.49 ENST00000476941.1
ENST00000273482.6
 TRPC1
 transient receptor potential cation channel, subfamily C, member 1
chr18_-_72265035 0.49 ENST00000585279.1
ENST00000580048.1
 LINC00909
 long intergenic non-protein coding RNA 909
chr6_-_91296737 0.48 ENST00000369332.3
ENST00000369329.3
 MAP3K7
 mitogen-activated protein kinase kinase kinase 7
chr11_-_72353451 0.47 ENST00000376450.3
 PDE2A
 phosphodiesterase 2A, cGMP-stimulated
chr2_+_219264466 0.47 ENST00000273062.2
 CTDSP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr14_-_23564320 0.46 ENST00000605057.1
 ACIN1
 apoptotic chromatin condensation inducer 1
chr1_-_156252590 0.46 ENST00000361813.5
ENST00000368267.5
 SMG5
 SMG5 nonsense mediated mRNA decay factor
chr17_-_41623009 0.46 ENST00000393664.2
 ETV4
 ets variant 4
chr6_-_91296602 0.45 ENST00000369325.3
ENST00000369327.3
 MAP3K7
 mitogen-activated protein kinase kinase kinase 7
chr7_+_86781847 0.45 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
 DMTF1
 cyclin D binding myb-like transcription factor 1
chr1_+_156338993 0.45 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
 RHBG
 Rh family, B glycoprotein (gene/pseudogene)
chr1_+_6845384 0.45 ENST00000303635.7
 CAMTA1
 calmodulin binding transcription activator 1
chr20_-_48532019 0.44 ENST00000289431.5
 SPATA2
 spermatogenesis associated 2
chr3_-_88108212 0.44 ENST00000482016.1
 CGGBP1
 CGG triplet repeat binding protein 1
chr2_-_220408430 0.43 ENST00000243776.6
 CHPF
 chondroitin polymerizing factor
chr7_+_86781677 0.42 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
 DMTF1
 cyclin D binding myb-like transcription factor 1
chrX_+_24167828 0.41 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
 ZFX
 zinc finger protein, X-linked
chr16_-_49890016 0.40 ENST00000563137.2
 ZNF423
 zinc finger protein 423
chr6_-_10415470 0.38 ENST00000379604.2
ENST00000379613.3
 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr20_+_34894247 0.38 ENST00000373913.3
 DLGAP4
 discs, large (Drosophila) homolog-associated protein 4
chr22_-_20004330 0.38 ENST00000263207.3
 ARVCF
 armadillo repeat gene deleted in velocardiofacial syndrome
chr16_-_89787360 0.38 ENST00000389386.3
 VPS9D1
 VPS9 domain containing 1
chrX_-_40594755 0.38 ENST00000324817.1
 MED14
 mediator complex subunit 14
chr1_-_23857698 0.38 ENST00000361729.2
 E2F2
 E2F transcription factor 2
chr14_-_77787198 0.37 ENST00000261534.4
 POMT2
 protein-O-mannosyltransferase 2
chr7_-_139876812 0.36 ENST00000397560.2
 JHDM1D
 lysine (K)-specific demethylase 7A
chr2_-_9695847 0.36 ENST00000310823.3
ENST00000497134.1
 ADAM17
 ADAM metallopeptidase domain 17
chr6_+_29795595 0.35 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
 HLA-G
 major histocompatibility complex, class I, G
chr19_-_16653325 0.34 ENST00000546361.2
 CHERP
 calcium homeostasis endoplasmic reticulum protein
chr8_-_93115445 0.34 ENST00000523629.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_64851729 0.34 ENST00000526791.1
ENST00000526945.1
 ZFPL1
 zinc finger protein-like 1
chr5_-_72744336 0.34 ENST00000499003.3
 FOXD1
 forkhead box D1
chr1_-_21503337 0.34 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
chr12_+_111051832 0.34 ENST00000550703.2
ENST00000551590.1
 TCTN1
 tectonic family member 1
chr12_+_120972606 0.33 ENST00000413266.2
 RNF10
 ring finger protein 10
chr19_-_16653226 0.32 ENST00000198939.6
 CHERP
 calcium homeostasis endoplasmic reticulum protein
chr12_+_111051902 0.31 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
 TCTN1
 tectonic family member 1
chr14_-_93651186 0.31 ENST00000556883.1
ENST00000298894.4
 MOAP1
 modulator of apoptosis 1
chr2_-_118771701 0.31 ENST00000376300.2
ENST00000319432.5
 CCDC93
 coiled-coil domain containing 93
chr5_-_180076613 0.30 ENST00000261937.6
ENST00000393347.3
 FLT4
 fms-related tyrosine kinase 4
chr4_-_11430221 0.30 ENST00000514690.1
 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr14_-_105262016 0.30 ENST00000407796.2
 AKT1
 v-akt murine thymoma viral oncogene homolog 1
chr8_-_101734308 0.30 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
 PABPC1
 poly(A) binding protein, cytoplasmic 1
chr9_+_137967366 0.30 ENST00000252854.4
 OLFM1
 olfactomedin 1
chrX_+_68725084 0.29 ENST00000252338.4
 FAM155B
 family with sequence similarity 155, member B
chr14_-_105262055 0.29 ENST00000349310.3
 AKT1
 v-akt murine thymoma viral oncogene homolog 1
chr20_-_48532046 0.29 ENST00000543716.1
 SPATA2
 spermatogenesis associated 2
chr17_+_43971643 0.29 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
 MAPT
 microtubule-associated protein tau
chr19_+_50353944 0.29 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
 PTOV1
 prostate tumor overexpressed 1
chr6_-_10415218 0.28 ENST00000466073.1
ENST00000498450.1
 TFAP2A
 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr12_+_122516626 0.28 ENST00000319080.7
 MLXIP
 MLX interacting protein
chr19_-_2151523 0.28 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
 AP3D1
 adaptor-related protein complex 3, delta 1 subunit
chr5_-_180076580 0.28 ENST00000502649.1
 FLT4
 fms-related tyrosine kinase 4
chr11_+_76092353 0.28 ENST00000530460.1
ENST00000321844.4
 RP11-111M22.2
 Homo sapiens putative uncharacterized protein FLJ37770-like (LOC100506127), mRNA.
chr7_-_19157248 0.27 ENST00000242261.5
 TWIST1
 twist family bHLH transcription factor 1
chr14_+_103851712 0.27 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
 MARK3
 MAP/microtubule affinity-regulating kinase 3
chr19_+_50354393 0.27 ENST00000391842.1
 PTOV1
 prostate tumor overexpressed 1
chr1_+_36023035 0.26 ENST00000373253.3
 NCDN
 neurochondrin
chr11_+_66025938 0.26 ENST00000394066.2
 KLC2
 kinesin light chain 2
chr11_-_62414070 0.26 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
 GANAB
 glucosidase, alpha; neutral AB
chr11_+_111473108 0.25 ENST00000304987.3
 SIK2
 salt-inducible kinase 2
chr9_-_112260531 0.25 ENST00000374541.2
ENST00000262539.3
 PTPN3
 protein tyrosine phosphatase, non-receptor type 3
chr9_-_131644202 0.25 ENST00000320665.6
ENST00000436267.2
 CCBL1
 cysteine conjugate-beta lyase, cytoplasmic
chr1_-_36022979 0.25 ENST00000469892.1
ENST00000325722.3
 KIAA0319L
 KIAA0319-like
chr3_+_50273625 0.25 ENST00000536647.1
 GNAI2
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.6 1.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.5 1.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5 6.7 GO:0038132 neuregulin binding(GO:0038132)
0.5 1.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 3.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.3 1.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 2.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 0.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 2.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 7.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 0.8 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 8.9 GO:0003785 actin monomer binding(GO:0003785)
0.2 4.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 7.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 1.4 GO:0005534 galactose binding(GO:0005534)
0.2 1.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.9 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.9 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 2.2 GO:0070064 proline-rich region binding(GO:0070064)
0.1 5.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 3.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 2.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 1.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0070025 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0 1.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 2.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 1.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328) modified amino acid transmembrane transporter activity(GO:0072349)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.6 1.9 GO:0060437 lung growth(GO:0060437)
0.6 5.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.5 6.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.5 2.5 GO:0030047 actin modification(GO:0030047)
0.5 6.7 GO:0010668 ectodermal cell differentiation(GO:0010668) nail development(GO:0035878)
0.5 1.4 GO:0001300 chronological cell aging(GO:0001300)
0.5 1.4 GO:0060926 cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.4 1.6 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.4 1.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3 2.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 1.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 1.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 0.7 GO:1900238 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.3 1.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 2.8 GO:0070141 response to UV-A(GO:0070141)
0.3 1.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 4.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.2 1.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 1.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.2 6.9 GO:0031643 positive regulation of myelination(GO:0031643)
0.2 1.6 GO:0090269 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.2 1.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 0.6 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 1.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 1.9 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 0.7 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 0.7 GO:0003409 optic cup structural organization(GO:0003409)
0.2 0.5 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of lymphangiogenesis(GO:1901491) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 1.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.9 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.1 0.5 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.6 GO:0097338 response to clozapine(GO:0097338)
0.1 1.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.4 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 3.3 GO:0036119 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.3 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.6 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.7 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 1.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 3.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 1.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 2.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.9 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.4 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 1.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 1.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.4 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 4.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.2 GO:0072092 olfactory bulb mitral cell layer development(GO:0061034) ureteric bud invasion(GO:0072092)
0.1 7.4 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.1 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 1.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.7 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 1.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.6 GO:0090037 regulation of blood vessel remodeling(GO:0060312) positive regulation of protein kinase C signaling(GO:0090037)
0.0 1.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 1.0 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.0 0.3 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.9 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.6 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.7 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 1.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 3.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.3 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 7.7 GO:0016050 vesicle organization(GO:0016050)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 4.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 4.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 4.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 5.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 7.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.9 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 2.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 6.4 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.3 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.5 1.4 GO:0072563 endothelial microparticle(GO:0072563)
0.4 2.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.2 3.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 4.5 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0016938 kinesin I complex(GO:0016938)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0045298 tubulin complex(GO:0045298)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 5.5 GO:0043195 terminal bouton(GO:0043195)
0.1 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 6.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.5 GO:0061574 ASAP complex(GO:0061574)
0.1 6.3 GO:0030175 filopodium(GO:0030175)
0.0 4.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0045202 synapse(GO:0045202)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 3.7 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 10.8 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 5.1 GO:0030027 lamellipodium(GO:0030027)
0.0 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0045178 basal part of cell(GO:0045178)
0.0 1.4 GO:0042641 actomyosin(GO:0042641)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)