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ENCODE cell lines, expression (Ernst 2011)

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Results for MECOM

Z-value: 0.72

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Transcription factors associated with MECOM

Gene Symbol Gene ID Gene Info
MECOM
ENSG00000085276.13 MECOM

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MECOMhg19_v2_chr3_-_168864427_168864464,
hg19_v2_chr3_-_169381183_169381258,
hg19_v2_chr3_-_168865522_168865536		0.097.3e-01Click!

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_74275057 2.08 ENST00000511370.1
 ALB
 albumin
chr3_-_145968923 1.91 ENST00000493382.1
ENST00000354952.2
ENST00000383083.2
 PLSCR4
 phospholipid scramblase 4
chr8_-_6420777 1.74 ENST00000415216.1
 ANGPT2
 angiopoietin 2
chr3_-_145968857 1.73 ENST00000433593.2
ENST00000476202.1
ENST00000460885.1
 PLSCR4
 phospholipid scramblase 4
chr17_+_53344945 1.70 ENST00000575345.1
 HLF
 hepatic leukemia factor
chr1_-_161193349 1.65 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
 APOA2
 apolipoprotein A-II
chr5_+_92919043 1.60 ENST00000327111.3
 NR2F1
 nuclear receptor subfamily 2, group F, member 1
chr5_+_102201722 1.29 ENST00000274392.9
ENST00000455264.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr5_+_102201509 1.20 ENST00000348126.2
ENST00000379787.4
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr12_-_15038779 1.18 ENST00000228938.5
ENST00000539261.1
 MGP
 matrix Gla protein
chr7_+_17338239 1.18 ENST00000242057.4
 AHR
 aryl hydrocarbon receptor
chr8_-_6420930 1.15 ENST00000325203.5
 ANGPT2
 angiopoietin 2
chr4_+_74301880 1.13 ENST00000395792.2
ENST00000226359.2
 AFP
 alpha-fetoprotein
chr6_-_52860171 1.11 ENST00000370963.4
 GSTA4
 glutathione S-transferase alpha 4
chr3_-_149093499 1.08 ENST00000472441.1
 TM4SF1
 transmembrane 4 L six family member 1
chr8_-_6420565 1.06 ENST00000338312.6
 ANGPT2
 angiopoietin 2
chr2_-_56150910 1.00 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
 EFEMP1
 EGF containing fibulin-like extracellular matrix protein 1
chr3_+_148583043 0.99 ENST00000296046.3
 CPA3
 carboxypeptidase A3 (mast cell)
chr8_-_6420759 0.91 ENST00000523120.1
 ANGPT2
 angiopoietin 2
chr4_+_155484155 0.85 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr1_-_146696901 0.82 ENST00000369272.3
ENST00000441068.2
 FMO5
 flavin containing monooxygenase 5
chr5_+_102201430 0.81 ENST00000438793.3
ENST00000346918.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chrX_+_15525426 0.69 ENST00000342014.6
 BMX
 BMX non-receptor tyrosine kinase
chr1_+_82266053 0.68 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
 LPHN2
 latrophilin 2
chr9_-_13175823 0.67 ENST00000545857.1
 MPDZ
 multiple PDZ domain protein
chrX_-_106243451 0.64 ENST00000355610.4
ENST00000535534.1
 MORC4
 MORC family CW-type zinc finger 4
chr2_+_242289502 0.62 ENST00000451310.1
 SEPT2
 septin 2
chr4_+_155484103 0.61 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr6_-_52859968 0.56 ENST00000370959.1
 GSTA4
 glutathione S-transferase alpha 4
chr13_+_76334567 0.54 ENST00000321797.8
 LMO7
 LIM domain 7
chr8_-_93029865 0.53 ENST00000422361.2
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_107690420 0.52 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
 ABCA1
 ATP-binding cassette, sub-family A (ABC1), member 1
chrX_-_43741594 0.51 ENST00000536181.1
ENST00000378069.4
 MAOB
 monoamine oxidase B
chr11_+_17316870 0.46 ENST00000458064.2
 NUCB2
 nucleobindin 2
chr2_+_37571717 0.45 ENST00000338415.3
ENST00000404976.1
 QPCT
 glutaminyl-peptide cyclotransferase
chrX_-_10588459 0.45 ENST00000380782.2
 MID1
 midline 1 (Opitz/BBB syndrome)
chr1_+_171060018 0.44 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
 FMO3
 flavin containing monooxygenase 3
chr13_+_102142296 0.42 ENST00000376162.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr6_+_153019069 0.42 ENST00000532295.1
 MYCT1
 myc target 1
chr14_+_22458631 0.42 ENST00000390444.1
 TRAV16
 T cell receptor alpha variable 16
chr3_-_178984759 0.41 ENST00000349697.2
ENST00000497599.1
 KCNMB3
 potassium large conductance calcium-activated channel, subfamily M beta member 3
chr6_+_153019023 0.41 ENST00000367245.5
ENST00000529453.1
 MYCT1
 myc target 1
chr7_-_100844193 0.41 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
 MOGAT3
 monoacylglycerol O-acyltransferase 3
chr19_-_47735918 0.40 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
 BBC3
 BCL2 binding component 3
chrX_+_67718863 0.39 ENST00000374622.2
 YIPF6
 Yip1 domain family, member 6
chrX_-_10588595 0.39 ENST00000423614.1
ENST00000317552.4
 MID1
 midline 1 (Opitz/BBB syndrome)
chr20_+_36012051 0.38 ENST00000373567.2
 SRC
 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr14_-_25479811 0.37 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr11_+_22696314 0.36 ENST00000532398.1
ENST00000433790.1
 GAS2
 growth arrest-specific 2
chr16_-_73093597 0.36 ENST00000397992.5
 ZFHX3
 zinc finger homeobox 3
chr1_-_98386543 0.36 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
 DPYD
 dihydropyrimidine dehydrogenase
chr14_+_64680854 0.36 ENST00000458046.2
 SYNE2
 spectrin repeat containing, nuclear envelope 2
chr4_-_40859132 0.34 ENST00000543538.1
ENST00000502841.1
ENST00000504305.1
ENST00000513516.1
ENST00000510670.1
 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
chr3_+_99357319 0.33 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
 COL8A1
 collagen, type VIII, alpha 1
chr17_-_56494882 0.32 ENST00000584437.1
 RNF43
 ring finger protein 43
chrX_+_66764375 0.30 ENST00000374690.3
 AR
 androgen receptor
chr17_-_56494908 0.30 ENST00000577716.1
 RNF43
 ring finger protein 43
chr9_+_134378289 0.29 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
 POMT1
 protein-O-mannosyltransferase 1
chr17_-_56494713 0.28 ENST00000407977.2
 RNF43
 ring finger protein 43
chrX_+_102883620 0.28 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr12_+_57522258 0.28 ENST00000553277.1
ENST00000243077.3
 LRP1
 low density lipoprotein receptor-related protein 1
chr2_+_172544294 0.27 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr2_+_172543967 0.27 ENST00000534253.2
ENST00000263811.4
ENST00000397119.3
ENST00000410079.3
ENST00000438879.1
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr2_+_172544011 0.27 ENST00000508530.1
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr2_-_1629176 0.26 ENST00000366424.2
 AC144450.2
 AC144450.2
chr2_+_189839046 0.26 ENST00000304636.3
ENST00000317840.5
 COL3A1
 collagen, type III, alpha 1
chr2_+_172544182 0.25 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr19_-_48894762 0.25 ENST00000600980.1
ENST00000330720.2
 KDELR1
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr14_+_24584508 0.25 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
 DCAF11
 DDB1 and CUL4 associated factor 11
chrX_+_2959512 0.24 ENST00000381127.1
 ARSF
 arylsulfatase F
chr14_-_24584138 0.24 ENST00000558280.1
ENST00000561028.1
 NRL
 neural retina leucine zipper
chr5_+_140739537 0.24 ENST00000522605.1
 PCDHGB2
 protocadherin gamma subfamily B, 2
chr11_-_18656028 0.24 ENST00000336349.5
 SPTY2D1
 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr1_-_208084729 0.24 ENST00000310833.7
ENST00000356522.4
 CD34
 CD34 molecule
chr22_+_29138013 0.23 ENST00000216027.3
ENST00000398941.2
 HSCB
 HscB mitochondrial iron-sulfur cluster co-chaperone
chrX_+_86772787 0.21 ENST00000373114.4
 KLHL4
 kelch-like family member 4
chr20_-_45985464 0.20 ENST00000458360.2
ENST00000262975.4
 ZMYND8
 zinc finger, MYND-type containing 8
chr2_+_55746746 0.20 ENST00000406691.3
ENST00000349456.4
ENST00000407816.3
ENST00000403007.3
 CCDC104
 coiled-coil domain containing 104
chr20_-_45984401 0.20 ENST00000311275.7
 ZMYND8
 zinc finger, MYND-type containing 8
chr2_+_172543919 0.18 ENST00000452242.1
ENST00000340296.4
 DYNC1I2
 dynein, cytoplasmic 1, intermediate chain 2
chr16_-_71758602 0.17 ENST00000568954.1
 PHLPP2
 PH domain and leucine rich repeat protein phosphatase 2
chr3_-_45883558 0.17 ENST00000445698.1
ENST00000296135.6
 LZTFL1
 leucine zipper transcription factor-like 1
chr7_-_115670804 0.17 ENST00000320239.7
 TFEC
 transcription factor EC
chr12_+_72080253 0.16 ENST00000549735.1
 TMEM19
 transmembrane protein 19
chr6_+_31515337 0.15 ENST00000376148.4
ENST00000376145.4
 NFKBIL1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr3_-_27498235 0.15 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
 SLC4A7
 solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr20_-_45985414 0.15 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
 ZMYND8
 zinc finger, MYND-type containing 8
chr9_+_82186682 0.15 ENST00000376552.2
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr20_-_45985172 0.14 ENST00000536340.1
 ZMYND8
 zinc finger, MYND-type containing 8
chr16_-_3930724 0.14 ENST00000262367.5
 CREBBP
 CREB binding protein
chr2_-_231989808 0.14 ENST00000258400.3
 HTR2B
 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr19_-_46366392 0.14 ENST00000598059.1
ENST00000594293.1
ENST00000245934.7
 SYMPK
 symplekin
chr5_-_115910091 0.13 ENST00000257414.8
 SEMA6A
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr16_-_50402836 0.13 ENST00000394688.3
 BRD7
 bromodomain containing 7
chr13_-_46626847 0.12 ENST00000242848.4
ENST00000282007.3
 ZC3H13
 zinc finger CCCH-type containing 13
chr10_-_29923893 0.11 ENST00000355867.4
 SVIL
 supervillin
chr10_+_57358750 0.11 ENST00000512524.2
 MTRNR2L5
 MT-RNR2-like 5
chr12_-_81763127 0.11 ENST00000541017.1
 PPFIA2
 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr8_-_133637624 0.11 ENST00000522789.1
 LRRC6
 leucine rich repeat containing 6
chr2_+_97779233 0.11 ENST00000461153.2
ENST00000420699.2
 ANKRD36
 ankyrin repeat domain 36
chr5_+_74807886 0.10 ENST00000514296.1
 POLK
 polymerase (DNA directed) kappa
chr6_+_29624898 0.09 ENST00000396704.3
ENST00000483013.1
ENST00000490427.1
ENST00000416766.2
ENST00000376891.4
ENST00000376898.3
ENST00000396701.2
ENST00000494692.1
ENST00000431798.2
 MOG
 myelin oligodendrocyte glycoprotein
chr2_+_108145913 0.09 ENST00000443205.1
 AC096669.3
 AC096669.3
chr3_+_39448180 0.09 ENST00000301821.6
ENST00000458478.1
ENST00000443003.1
 RPSA
 ribosomal protein SA
chr7_+_97361388 0.09 ENST00000350485.4
ENST00000346867.4
 TAC1
 tachykinin, precursor 1
chr11_+_61008514 0.09 ENST00000312403.5
 PGA5
 pepsinogen 5, group I (pepsinogen A)
chr19_+_36630454 0.09 ENST00000246533.3
 CAPNS1
 calpain, small subunit 1
chr15_-_48470558 0.08 ENST00000324324.7
 MYEF2
 myelin expression factor 2
chrX_-_85302531 0.08 ENST00000537751.1
ENST00000358786.4
ENST00000357749.2
 CHM
 choroideremia (Rab escort protein 1)
chr16_-_50402690 0.08 ENST00000394689.2
 BRD7
 bromodomain containing 7
chr5_+_54320078 0.08 ENST00000231009.2
 GZMK
 granzyme K (granzyme 3; tryptase II)
chr12_+_15699286 0.08 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr17_-_37308824 0.08 ENST00000415163.1
ENST00000441877.1
ENST00000444911.2
 PLXDC1
 plexin domain containing 1
chr8_-_39695719 0.08 ENST00000347580.4
ENST00000379853.2
ENST00000521880.1
 ADAM2
 ADAM metallopeptidase domain 2
chr9_+_82186872 0.08 ENST00000376544.3
ENST00000376520.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr14_-_102701740 0.08 ENST00000561150.1
ENST00000522867.1
 MOK
 MOK protein kinase
chr11_+_60989688 0.08 ENST00000378149.3
ENST00000422676.2
 PGA4
 pepsinogen 4, group I (pepsinogen A)
chr12_+_72079842 0.08 ENST00000266673.5
ENST00000550524.1
 TMEM19
 transmembrane protein 19
chr3_-_38992052 0.08 ENST00000302328.3
ENST00000450244.1
ENST00000444237.2
 SCN11A
 sodium channel, voltage-gated, type XI, alpha subunit
chr16_+_10837643 0.08 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
 NUBP1
 nucleotide binding protein 1
chr8_-_39695764 0.07 ENST00000265708.4
 ADAM2
 ADAM metallopeptidase domain 2
chr12_+_96588279 0.07 ENST00000552142.1
 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
chr15_+_71185148 0.07 ENST00000443425.2
ENST00000560755.1
 LRRC49
 leucine rich repeat containing 49
chr1_+_15802594 0.07 ENST00000375910.3
 CELA2B
 chymotrypsin-like elastase family, member 2B
chr12_+_21207503 0.07 ENST00000545916.1
 SLCO1B7
 solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_-_81763184 0.06 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
 PPFIA2
 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_+_160160283 0.06 ENST00000368079.3
 CASQ1
 calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_172422026 0.06 ENST00000367725.4
 C1orf105
 chromosome 1 open reading frame 105
chr1_+_160160346 0.06 ENST00000368078.3
 CASQ1
 calsequestrin 1 (fast-twitch, skeletal muscle)
chrX_+_155227246 0.05 ENST00000244174.5
ENST00000424344.3
 IL9R
 interleukin 9 receptor
chr16_-_90096309 0.05 ENST00000408886.2
 C16orf3
 chromosome 16 open reading frame 3
chr6_-_10882174 0.05 ENST00000379491.4
 GCM2
 glial cells missing homolog 2 (Drosophila)
chr20_+_36932521 0.04 ENST00000262865.4
 BPI
 bactericidal/permeability-increasing protein
chr2_+_27435734 0.04 ENST00000419744.1
 ATRAID
 all-trans retinoic acid-induced differentiation factor
chr6_-_154831779 0.04 ENST00000607772.1
 CNKSR3
 CNKSR family member 3
chr16_+_9449445 0.04 ENST00000564305.1
 RP11-243A14.1
 RP11-243A14.1
chr9_+_33240157 0.04 ENST00000379721.3
 SPINK4
 serine peptidase inhibitor, Kazal type 4
chr4_-_74847800 0.04 ENST00000296029.3
 PF4
 platelet factor 4
chr6_-_31514516 0.04 ENST00000303892.5
ENST00000483251.1
 ATP6V1G2
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr13_-_113242439 0.04 ENST00000375669.3
ENST00000261965.3
 TUBGCP3
 tubulin, gamma complex associated protein 3
chr3_+_147127142 0.04 ENST00000282928.4
 ZIC1
 Zic family member 1
chr12_+_21168630 0.04 ENST00000421593.2
 SLCO1B7
 solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_-_184971853 0.03 ENST00000231887.3
 EHHADH
 enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr7_-_15601595 0.03 ENST00000342526.3
 AGMO
 alkylglycerol monooxygenase
chr22_+_36113919 0.03 ENST00000249044.2
 APOL5
 apolipoprotein L, 5
chr13_+_49280951 0.03 ENST00000282018.3
 CYSLTR2
 cysteinyl leukotriene receptor 2
chr22_-_31688431 0.03 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
 PIK3IP1
 phosphoinositide-3-kinase interacting protein 1
chr14_-_24551195 0.03 ENST00000560550.1
 NRL
 neural retina leucine zipper
chr19_+_48497962 0.02 ENST00000596043.1
ENST00000597519.1
 ELSPBP1
 epididymal sperm binding protein 1
chr4_-_77997126 0.02 ENST00000537948.1
ENST00000507788.1
ENST00000237654.4
 CCNI
 cyclin I
chr4_-_88450244 0.02 ENST00000503414.1
 SPARCL1
 SPARC-like 1 (hevin)
chr8_+_134203303 0.02 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
 WISP1
 WNT1 inducible signaling pathway protein 1
chr19_-_10614386 0.02 ENST00000171111.5
 KEAP1
 kelch-like ECH-associated protein 1
chr17_-_43138357 0.02 ENST00000342350.5
 DCAKD
 dephospho-CoA kinase domain containing
chr19_-_9785743 0.01 ENST00000537617.1
ENST00000589542.1
ENST00000590155.1
ENST00000541032.1
ENST00000588653.1
ENST00000448622.1
ENST00000453792.2
 ZNF562
 zinc finger protein 562
chr1_-_92949505 0.01 ENST00000370332.1
 GFI1
 growth factor independent 1 transcription repressor
chr17_-_10276319 0.01 ENST00000252172.4
ENST00000418404.3
 MYH13
 myosin, heavy chain 13, skeletal muscle
chr14_-_75179774 0.01 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
 AREL1
AC007956.1
 apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr1_+_25664408 0.01 ENST00000374358.4
 TMEM50A
 transmembrane protein 50A
chr5_-_147162078 0.01 ENST00000507386.1
 JAKMIP2
 janus kinase and microtubule interacting protein 2
chr6_+_31514622 0.01 ENST00000376146.4
 NFKBIL1
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr19_+_47538560 0.00 ENST00000439365.2
ENST00000594670.1
 NPAS1
 neuronal PAS domain protein 1
chr8_+_134203273 0.00 ENST00000250160.6
 WISP1
 WNT1 inducible signaling pathway protein 1
chr5_+_140165876 0.00 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
 PCDHA1
 protocadherin alpha 1
chr3_+_121311966 0.00 ENST00000338040.4
 FBXO40
 F-box protein 40

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.4 1.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.3 3.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.3 1.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 1.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.8 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.2 0.5 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 2.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 4.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.8 3.3 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.7 2.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 1.6 GO:2000910 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.3 3.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 0.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.5 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 1.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0032489 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.4 GO:0006145 purine nucleobase catabolic process(GO:0006145) beta-alanine metabolic process(GO:0019482)
0.1 0.7 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.3 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.1 0.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.5 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.7 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.2 GO:0038001 paracrine signaling(GO:0038001) glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1 0.3 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 1.6 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.0 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 1.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 1.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 3.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.0 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.3 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:1904724 tertiary granule lumen(GO:1904724)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects