ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
MEF2D Links Ensembl NCBI GeneCards UniProt	ENSG00000116604.13	MEF2D
MEF2A Links Ensembl NCBI GeneCards UniProt	ENSG00000068305.13	MEF2A

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MEF2A	hg19_v2_chr15_+_100106155_100106243	0.58	1.9e-02	Click!
MEF2D	hg19_v2_chr1_-_156460391_156460417, hg19_v2_chr1_-_156470556_156470643	0.19	4.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr1_-_201391149	12.28	ENST00000555948.1 ENST00000556362.1	TNNI1	troponin I type 1 (skeletal, slow)
chr5_-_111091948	9.25	ENST00000447165.2	NREP	neuronal regeneration related protein
chr2_-_211168332	8.84	ENST00000341685.4	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr3_+_138067521	8.26	ENST00000494949.1	MRAS	muscle RAS oncogene homolog
chr10_-_75415825	7.41	ENST00000394810.2	SYNPO2L	synaptopodin 2-like
chr5_+_53751445	7.40	ENST00000302005.1	HSPB3	heat shock 27kDa protein 3
chr3_-_52486841	7.27	ENST00000496590.1	TNNC1	troponin C type 1 (slow)
chrX_-_21776281	7.24	ENST00000379494.3	SMPX	small muscle protein, X-linked
chr2_-_190044480	5.95	ENST00000374866.3	COL5A2	collagen, type V, alpha 2
chr3_+_138067314	5.54	ENST00000423968.2	MRAS	muscle RAS oncogene homolog
chr3_+_138067666	5.39	ENST00000475711.1 ENST00000464896.1	MRAS	muscle RAS oncogene homolog
chr2_-_211179883	5.14	ENST00000352451.3	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr1_-_116311402	5.08	ENST00000261448.5	CASQ2	calsequestrin 2 (cardiac muscle)
chr10_-_75410771	4.63	ENST00000372873.4	SYNPO2L	synaptopodin 2-like
chr2_+_170366203	4.52	ENST00000284669.1	KLHL41	kelch-like family member 41
chr1_+_114522049	4.22	ENST00000369551.1 ENST00000320334.4	OLFML3	olfactomedin-like 3
chr12_+_119616447	3.91	ENST00000281938.2	HSPB8	heat shock 22kDa protein 8
chr4_+_41362796	3.81	ENST00000508501.1 ENST00000512946.1 ENST00000313860.7 ENST00000512632.1 ENST00000512820.1	LIMCH1	LIM and calponin homology domains 1
chr5_-_150521192	3.80	ENST00000523714.1 ENST00000521749.1	ANXA6	annexin A6
chr1_-_173174681	3.77	ENST00000367718.1	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr1_-_201390846	3.66	ENST00000367312.1 ENST00000555340.2 ENST00000361379.4	TNNI1	troponin I type 1 (skeletal, slow)
chr20_+_9049682	3.34	ENST00000334005.3 ENST00000378473.3	PLCB4	phospholipase C, beta 4
chr1_-_153518270	3.28	ENST00000354332.4 ENST00000368716.4	S100A4	S100 calcium binding protein A4
chr9_-_75567962	3.18	ENST00000297785.3 ENST00000376939.1	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr3_-_145878954	3.05	ENST00000282903.5 ENST00000360060.3	PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr17_+_4855053	3.03	ENST00000518175.1	ENO3	enolase 3 (beta, muscle)
chr1_-_201346761	2.98	ENST00000455702.1 ENST00000422165.1 ENST00000367318.5 ENST00000367320.2 ENST00000438742.1 ENST00000412633.1 ENST00000458432.2 ENST00000421663.2 ENST00000367322.1 ENST00000509001.1	TNNT2	troponin T type 2 (cardiac)
chr17_-_10325261	2.97	ENST00000403437.2	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr4_-_186697044	2.96	ENST00000437304.2	SORBS2	sorbin and SH3 domain containing 2
chr12_-_111358372	2.87	ENST00000548438.1 ENST00000228841.8	MYL2	myosin, light chain 2, regulatory, cardiac, slow
chr2_+_233497931	2.85	ENST00000264059.3	EFHD1	EF-hand domain family, member D1
chr5_+_155753745	2.56	ENST00000435422.3 ENST00000337851.4 ENST00000447401.1	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr13_+_76334567	2.52	ENST00000321797.8	LMO7	LIM domain 7
chr13_-_67802549	2.52	ENST00000328454.5 ENST00000377865.2	PCDH9	protocadherin 9
chr12_-_91539918	2.52	ENST00000548218.1	DCN	decorin
chr1_-_203144941	2.52	ENST00000255416.4	MYBPH	myosin binding protein H
chr13_+_76334795	2.49	ENST00000526202.1 ENST00000465261.2	LMO7	LIM domain 7
chr3_+_99357319	2.47	ENST00000452013.1 ENST00000261037.3 ENST00000273342.4	COL8A1	collagen, type VIII, alpha 1
chr1_+_145524891	2.47	ENST00000369304.3	ITGA10	integrin, alpha 10
chr4_+_120056939	2.36	ENST00000307128.5	MYOZ2	myozenin 2
chr10_+_88428206	2.35	ENST00000429277.2 ENST00000458213.2 ENST00000352360.5	LDB3	LIM domain binding 3
chr11_+_1942580	2.34	ENST00000381558.1	TNNT3	troponin T type 3 (skeletal, fast)
chr4_-_143226979	2.24	ENST00000514525.1	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_+_153046456	2.14	ENST00000393786.3 ENST00000370104.1 ENST00000370108.3 ENST00000370101.3 ENST00000430541.1 ENST00000370100.1	SRPK3	SRSF protein kinase 3
chr6_+_132129151	2.14	ENST00000360971.2	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr4_+_169418195	2.13	ENST00000261509.6 ENST00000335742.7	PALLD	palladin, cytoskeletal associated protein
chr10_-_95241951	2.11	ENST00000358334.5 ENST00000359263.4 ENST00000371488.3	MYOF	myoferlin
chr10_-_95242044	2.10	ENST00000371501.4 ENST00000371502.4 ENST00000371489.1	MYOF	myoferlin
chr2_+_220283091	2.09	ENST00000373960.3	DES	desmin
chr9_+_139871948	2.07	ENST00000224167.2 ENST00000457950.1 ENST00000371625.3 ENST00000371623.3	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr11_+_1940925	2.05	ENST00000453458.1 ENST00000381557.2 ENST00000381589.3 ENST00000381579.3 ENST00000381563.4 ENST00000344578.4	TNNT3	troponin T type 3 (skeletal, fast)
chr10_-_62704005	2.05	ENST00000337910.5	RHOBTB1	Rho-related BTB domain containing 1
chr16_+_7382745	1.95	ENST00000436368.2 ENST00000311745.5 ENST00000355637.4 ENST00000340209.4	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_+_112832202	1.95	ENST00000534015.1	NCAM1	neural cell adhesion molecule 1
chr9_+_116327326	1.94	ENST00000342620.5	RGS3	regulator of G-protein signaling 3
chr3_+_8543393	1.91	ENST00000157600.3 ENST00000415597.1 ENST00000535732.1	LMCD1	LIM and cysteine-rich domains 1
chr2_-_106054952	1.87	ENST00000336660.5 ENST00000393352.3 ENST00000607522.1	FHL2	four and a half LIM domains 2
chr4_-_186696425	1.84	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2	sorbin and SH3 domain containing 2
chr1_-_31845914	1.79	ENST00000373713.2	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr3_+_8543561	1.76	ENST00000397386.3	LMCD1	LIM and cysteine-rich domains 1
chr3_-_114343039	1.76	ENST00000481632.1	ZBTB20	zinc finger and BTB domain containing 20
chr5_-_42811986	1.75	ENST00000511224.1 ENST00000507920.1 ENST00000510965.1	SEPP1	selenoprotein P, plasma, 1
chrX_+_70521584	1.70	ENST00000373829.3 ENST00000538820.1	ITGB1BP2	integrin beta 1 binding protein (melusin) 2
chr2_-_151344172	1.68	ENST00000375734.2 ENST00000263895.4 ENST00000454202.1	RND3	Rho family GTPase 3
chr11_+_1860200	1.63	ENST00000381911.1	TNNI2	troponin I type 2 (skeletal, fast)
chr5_-_42812143	1.61	ENST00000514985.1	SEPP1	selenoprotein P, plasma, 1
chr6_-_169654139	1.60	ENST00000366787.3	THBS2	thrombospondin 2
chr17_-_10421853	1.57	ENST00000226207.5	MYH1	myosin, heavy chain 1, skeletal muscle, adult
chr12_+_81101277	1.55	ENST00000228641.3	MYF6	myogenic factor 6 (herculin)
chr7_-_150946015	1.55	ENST00000262188.8	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_12399071	1.54	ENST00000539723.1 ENST00000550549.1	PARVA	parvin, alpha
chr11_+_112832133	1.53	ENST00000524665.1	NCAM1	neural cell adhesion molecule 1
chr4_+_169418255	1.49	ENST00000505667.1 ENST00000511948.1	PALLD	palladin, cytoskeletal associated protein
chr5_-_88179302	1.46	ENST00000504921.2	MEF2C	myocyte enhancer factor 2C
chr10_+_88428370	1.35	ENST00000372066.3 ENST00000263066.6 ENST00000372056.4 ENST00000310944.6 ENST00000361373.4 ENST00000542786.1	LDB3	LIM domain binding 3
chr11_+_12766583	1.34	ENST00000361985.2	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_+_1993152	1.33	ENST00000262113.4	MYOM2	myomesin 2
chr3_+_8543533	1.33	ENST00000454244.1	LMCD1	LIM and cysteine-rich domains 1
chr16_+_6069072	1.33	ENST00000547605.1 ENST00000550418.1 ENST00000553186.1	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_+_179370517	1.30	ENST00000263966.3	USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)
chr15_+_100106126	1.29	ENST00000558812.1 ENST00000338042.6	MEF2A	myocyte enhancer factor 2A
chr17_+_68165657	1.29	ENST00000243457.3	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr14_-_102704783	1.28	ENST00000522534.1	MOK	MOK protein kinase
chr17_-_1389419	1.26	ENST00000575158.1	MYO1C	myosin IC
chr17_-_1389228	1.24	ENST00000438665.2	MYO1C	myosin IC
chr3_+_135741576	1.22	ENST00000334546.2	PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr11_+_112832090	1.22	ENST00000533760.1	NCAM1	neural cell adhesion molecule 1
chr1_-_154164534	1.21	ENST00000271850.7 ENST00000368530.2	TPM3	tropomyosin 3
chrX_-_128657457	1.20	ENST00000371121.3 ENST00000371123.1 ENST00000371122.4	SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr15_+_100106244	1.18	ENST00000557942.1	MEF2A	myocyte enhancer factor 2A
chr7_-_134143841	1.15	ENST00000285930.4	AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)
chr3_+_35721106	1.15	ENST00000474696.1 ENST00000412048.1 ENST00000396482.2 ENST00000432682.1	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr8_+_1993173	1.13	ENST00000523438.1	MYOM2	myomesin 2
chr18_-_53070913	1.11	ENST00000568186.1 ENST00000564228.1	TCF4	transcription factor 4
chr11_+_1860832	1.08	ENST00000252898.7	TNNI2	troponin I type 2 (skeletal, fast)
chr4_-_143767428	1.06	ENST00000513000.1 ENST00000509777.1 ENST00000503927.1	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_+_80186908	1.06	ENST00000582743.1 ENST00000578684.1 ENST00000577650.1 ENST00000582715.1	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3
chr15_+_100106155	1.05	ENST00000557785.1 ENST00000558049.1 ENST00000449277.2	MEF2A	myocyte enhancer factor 2A
chr1_-_59249732	1.04	ENST00000371222.2	JUN	jun proto-oncogene
chr9_-_130639997	1.03	ENST00000373176.1	AK1	adenylate kinase 1
chr11_+_1860682	0.98	ENST00000381906.1	TNNI2	troponin I type 2 (skeletal, fast)
chr1_+_84630645	0.93	ENST00000394839.2	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr12_-_16759711	0.91	ENST00000447609.1	LMO3	LIM domain only 3 (rhombotin-like 2)
chr3_+_159570722	0.85	ENST00000482804.1	SCHIP1	schwannomin interacting protein 1
chr12_-_9268707	0.84	ENST00000318602.7	A2M	alpha-2-macroglobulin
chr17_+_65040678	0.81	ENST00000226021.3	CACNG1	calcium channel, voltage-dependent, gamma subunit 1
chr4_-_143227088	0.79	ENST00000511838.1	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr11_+_1940786	0.79	ENST00000278317.6 ENST00000381561.4 ENST00000381548.3 ENST00000360603.3 ENST00000381549.3	TNNT3	troponin T type 3 (skeletal, fast)
chr11_+_65082289	0.78	ENST00000279249.2	CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2
chr1_+_160085501	0.78	ENST00000361216.3	ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr19_+_3933579	0.73	ENST00000593949.1	NMRK2	nicotinamide riboside kinase 2
chr6_+_41021027	0.70	ENST00000244669.2	APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr16_-_31439735	0.70	ENST00000287490.4	COX6A2	cytochrome c oxidase subunit VIa polypeptide 2
chr19_+_3933085	0.69	ENST00000168977.2 ENST00000599576.1	NMRK2	nicotinamide riboside kinase 2
chr1_-_204329013	0.67	ENST00000272203.3 ENST00000414478.1	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr4_+_95373037	0.67	ENST00000359265.4 ENST00000437932.1 ENST00000380180.3 ENST00000318007.5 ENST00000450793.1 ENST00000538141.1 ENST00000317968.4 ENST00000512274.1 ENST00000503974.1 ENST00000504489.1 ENST00000542407.1	PDLIM5	PDZ and LIM domain 5
chr20_+_44519948	0.63	ENST00000354880.5 ENST00000191018.5	CTSA	cathepsin A
chr6_+_108977520	0.63	ENST00000540898.1	FOXO3	forkhead box O3
chr10_-_49860525	0.61	ENST00000435790.2	ARHGAP22	Rho GTPase activating protein 22
chr1_+_156211753	0.59	ENST00000368272.4	BGLAP	bone gamma-carboxyglutamate (gla) protein
chr2_+_161993412	0.59	ENST00000259075.2 ENST00000432002.1	TANK	TRAF family member-associated NFKB activator
chr2_+_44502597	0.57	ENST00000260649.6 ENST00000409387.1	SLC3A1	solute carrier family 3 (amino acid transporter heavy chain), member 1
chr20_+_44520009	0.55	ENST00000607482.1 ENST00000372459.2	CTSA	cathepsin A
chr17_+_27369918	0.53	ENST00000323372.4	PIPOX	pipecolic acid oxidase
chr2_+_161993465	0.53	ENST00000457476.1	TANK	TRAF family member-associated NFKB activator
chr1_+_25757376	0.52	ENST00000399766.3 ENST00000399763.3 ENST00000374343.4	TMEM57	transmembrane protein 57
chr8_-_49834299	0.49	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr4_+_129730779	0.49	ENST00000226319.6	PHF17	jade family PHD finger 1
chr9_-_74980113	0.48	ENST00000376962.5 ENST00000376960.4 ENST00000237937.3	ZFAND5	zinc finger, AN1-type domain 5
chr20_+_1875110	0.48	ENST00000400068.3	SIRPA	signal-regulatory protein alpha
chr2_+_85766280	0.46	ENST00000306434.3	MAT2A	methionine adenosyltransferase II, alpha
chr8_-_49833978	0.46	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr16_+_8768422	0.46	ENST00000268251.8 ENST00000564714.1	ABAT	4-aminobutyrate aminotransferase
chr10_-_126847276	0.45	ENST00000531469.1	CTBP2	C-terminal binding protein 2
chr1_+_203097407	0.43	ENST00000367235.1	ADORA1	adenosine A1 receptor
chr1_+_201979645	0.43	ENST00000367284.5 ENST00000367283.3	ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr4_-_83765613	0.43	ENST00000503937.1	SEC31A	SEC31 homolog A (S. cerevisiae)
chr2_+_162087577	0.42	ENST00000439442.1	TANK	TRAF family member-associated NFKB activator
chr8_-_13372395	0.42	ENST00000276297.4 ENST00000511869.1	DLC1	deleted in liver cancer 1
chrX_-_11284095	0.41	ENST00000303025.6 ENST00000534860.1	ARHGAP6	Rho GTPase activating protein 6
chr1_-_94079648	0.41	ENST00000370247.3	BCAR3	breast cancer anti-estrogen resistance 3
chr12_+_15699286	0.40	ENST00000442921.2 ENST00000542557.1 ENST00000445537.2 ENST00000544244.1	PTPRO	protein tyrosine phosphatase, receptor type, O
chr19_+_35629702	0.40	ENST00000351325.4	FXYD1	FXYD domain containing ion transport regulator 1
chr1_+_156096336	0.39	ENST00000504687.1 ENST00000473598.2	LMNA	lamin A/C
chr1_-_27240455	0.37	ENST00000254227.3	NR0B2	nuclear receptor subfamily 0, group B, member 2
chr1_+_150245177	0.37	ENST00000369098.3	C1orf54	chromosome 1 open reading frame 54
chr10_+_28966271	0.36	ENST00000375533.3	BAMBI	BMP and activin membrane-bound inhibitor
chr7_-_151217166	0.34	ENST00000496004.1	RHEB	Ras homolog enriched in brain
chr6_-_6007200	0.34	ENST00000244766.2	NRN1	neuritin 1
chr17_+_42264322	0.34	ENST00000446571.3 ENST00000357984.3 ENST00000538716.2	TMUB2	transmembrane and ubiquitin-like domain containing 2
chr8_-_62602327	0.33	ENST00000445642.3 ENST00000517847.2 ENST00000389204.4 ENST00000517661.1 ENST00000517903.1 ENST00000522603.1 ENST00000522349.1 ENST00000522835.1 ENST00000541428.1 ENST00000518306.1	ASPH	aspartate beta-hydroxylase
chr8_+_74903580	0.32	ENST00000284818.2 ENST00000518893.1	LY96	lymphocyte antigen 96
chr19_+_35630022	0.32	ENST00000589209.1	FXYD1	FXYD domain containing ion transport regulator 1
chr12_+_21207503	0.31	ENST00000545916.1	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr7_-_27169801	0.29	ENST00000511914.1	HOXA4	homeobox A4
chr17_+_7788104	0.28	ENST00000380358.4	CHD3	chromodomain helicase DNA binding protein 3
chr3_+_46924829	0.28	ENST00000313049.5	PTH1R	parathyroid hormone 1 receptor
chr1_+_156095951	0.26	ENST00000448611.2 ENST00000368297.1	LMNA	lamin A/C
chr5_+_140552218	0.26	ENST00000231137.3	PCDHB7	protocadherin beta 7
chr22_-_31742218	0.26	ENST00000266269.5 ENST00000405309.3 ENST00000351933.4	PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr15_+_80364901	0.25	ENST00000560228.1 ENST00000559835.1 ENST00000559775.1 ENST00000558688.1 ENST00000560392.1 ENST00000560976.1 ENST00000558272.1 ENST00000558390.1	ZFAND6	zinc finger, AN1-type domain 6
chr17_-_36891830	0.23	ENST00000578487.1	PCGF2	polycomb group ring finger 2
chr7_-_151217001	0.23	ENST00000262187.5	RHEB	Ras homolog enriched in brain
chr3_-_27498235	0.21	ENST00000295736.5 ENST00000428386.1 ENST00000428179.1	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr10_-_74114714	0.20	ENST00000338820.3 ENST00000394903.2 ENST00000444643.2	DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12
chr2_+_113403434	0.19	ENST00000272542.3	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr14_+_100150622	0.19	ENST00000261835.3	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1
chr1_+_150245099	0.19	ENST00000369099.3	C1orf54	chromosome 1 open reading frame 54
chr17_-_34344991	0.18	ENST00000591423.1	CCL23	chemokine (C-C motif) ligand 23
chr17_+_42264556	0.17	ENST00000319511.6 ENST00000589785.1 ENST00000592825.1 ENST00000589184.1	TMUB2	transmembrane and ubiquitin-like domain containing 2
chr15_-_52821020	0.17	ENST00000553916.1	MYO5A	myosin VA (heavy chain 12, myoxin)
chr12_-_125401885	0.16	ENST00000542416.1	UBC	ubiquitin C
chr1_+_24018269	0.15	ENST00000374550.3	RPL11	ribosomal protein L11
chr7_+_120629653	0.15	ENST00000450913.2 ENST00000340646.5	CPED1	cadherin-like and PC-esterase domain containing 1
chr9_-_33402506	0.15	ENST00000377425.4 ENST00000537089.1 ENST00000297988.1 ENST00000539936.1 ENST00000541274.1	AQP7	aquaporin 7
chr3_-_47934234	0.15	ENST00000420772.2	MAP4	microtubule-associated protein 4
chr12_+_12938541	0.14	ENST00000356591.4	APOLD1	apolipoprotein L domain containing 1
chr17_-_34345002	0.13	ENST00000293280.2	CCL23	chemokine (C-C motif) ligand 23
chr12_+_20963647	0.13	ENST00000381545.3	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr12_+_20963632	0.13	ENST00000540853.1 ENST00000261196.2	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr12_+_110562135	0.12	ENST00000361948.4 ENST00000552912.1 ENST00000242591.5 ENST00000546374.1	IFT81	intraflagellar transport 81 homolog (Chlamydomonas)
chr22_+_41258250	0.11	ENST00000544094.1	XPNPEP3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chrX_+_119384607	0.11	ENST00000326624.2 ENST00000557385.1	ZBTB33	zinc finger and BTB domain containing 33
chr17_-_10276319	0.11	ENST00000252172.4 ENST00000418404.3	MYH13	myosin, heavy chain 13, skeletal muscle
chr1_+_221051699	0.10	ENST00000366903.6	HLX	H2.0-like homeobox
chr1_-_169703203	0.10	ENST00000333360.7 ENST00000367781.4 ENST00000367782.4 ENST00000367780.4 ENST00000367779.4	SELE	selectin E
chr1_+_36621697	0.10	ENST00000373150.4 ENST00000373151.2	MAP7D1	MAP7 domain containing 1
chr14_+_72052983	0.09	ENST00000358550.2	SIPA1L1	signal-induced proliferation-associated 1 like 1
chr20_+_11898507	0.07	ENST00000378226.2	BTBD3	BTB (POZ) domain containing 3
chr21_+_19617140	0.07	ENST00000299295.2 ENST00000338326.3	CHODL	chondrolectin
chr16_+_84328252	0.07	ENST00000219454.5	WFDC1	WAP four-disulfide core domain 1
chr3_+_121311966	0.07	ENST00000338040.4	FBXO40	F-box protein 40
chr14_+_56078695	0.07	ENST00000416613.1	KTN1	kinectin 1 (kinesin receptor)
chr1_-_46642154	0.06	ENST00000540385.1	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr12_-_45269430	0.06	ENST00000395487.2	NELL2	NEL-like 2 (chicken)
chr1_+_151129135	0.06	ENST00000602841.1	SCNM1	sodium channel modifier 1
chr9_-_215744	0.05	ENST00000382387.2	C9orf66	chromosome 9 open reading frame 66
chrX_+_18725758	0.05	ENST00000472826.1 ENST00000544635.1 ENST00000496075.2	PPEF1	protein phosphatase, EF-hand calcium binding domain 1
chr10_+_52750930	0.04	ENST00000401604.2	PRKG1	protein kinase, cGMP-dependent, type I
chr18_-_64271363	0.04	ENST00000262150.2	CDH19	cadherin 19, type 2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	10.3	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
1.5	5.9	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
1.3	3.8	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.1	15.9	GO:0014883	transition between fast and slow fiber(GO:0014883)
1.1	3.2	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.0	3.1	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.6	1.8	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.6	3.5	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.5	3.9	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.5	1.9	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.5	5.1	GO:0086029	Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.4	2.5	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4	2.9	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.4	5.3	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.4	1.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.4	1.5	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4	24.4	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3	3.7	GO:0001778	plasma membrane repair(GO:0001778)
0.3	1.3	GO:0035523	protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.3	1.3	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.3	1.0	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3	1.6	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.3	2.1	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3	1.1	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.3	1.0	GO:0035026	leading edge cell differentiation(GO:0035026)
0.3	1.5	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2	0.6	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.2	5.5	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2	0.9	GO:0097338	response to clozapine(GO:0097338)
0.2	0.5	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2	4.2	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2	3.6	GO:0003334	keratinocyte development(GO:0003334)
0.2	3.8	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.2	0.8	GO:1903279	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) regulation of calcium:sodium antiporter activity(GO:1903279)
0.2	0.9	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2	12.0	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.1	0.4	GO:0032900	regulation of nucleoside transport(GO:0032242) negative regulation of neurotrophin production(GO:0032900)
0.1	1.7	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	19.6	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1	1.5	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.1	0.4	GO:0036060	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1	1.2	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1	0.7	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1	0.6	GO:0032571	response to vitamin K(GO:0032571) response to hydroxyisoflavone(GO:0033594)
0.1	0.7	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	2.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.5	GO:1904448	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) positive regulation of prolactin secretion(GO:1902722) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1	1.2	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	0.3	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1	1.6	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	0.5	GO:0010732	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1	1.1	GO:0034605	cellular response to heat(GO:0034605)
0.1	0.6	GO:1990822	L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.1	2.7	GO:0045214	sarcomere organization(GO:0045214)
0.1	7.0	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.1	0.6	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.1	2.7	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.1	0.7	GO:0030239	myofibril assembly(GO:0030239)
0.1	0.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.3	GO:0032091	negative regulation of protein binding(GO:0032091)
0.1	1.4	GO:0009435	NAD biosynthetic process(GO:0009435)
0.1	1.1	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.1	3.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.2	GO:0015793	glycerol transport(GO:0015793)
0.0	1.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.3	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	2.4	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.4	GO:0060056	mammary gland involution(GO:0060056)
0.0	1.8	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.4	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	4.5	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	3.9	GO:1900034	regulation of cellular response to heat(GO:1900034)
0.0	0.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	1.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.2	GO:0051643	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) secretory granule localization(GO:0032252) endoplasmic reticulum localization(GO:0051643)
0.0	2.0	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	5.2	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.2	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	2.7	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	1.0	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	2.5	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.5	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	1.2	GO:0061053	somite development(GO:0061053)
0.0	0.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	2.9	GO:0006941	striated muscle contraction(GO:0006941)
0.0	2.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	2.0	GO:0060047	heart contraction(GO:0060047)
0.0	4.7	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	0.6	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	2.4	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.1	GO:0097205	glomerular filtration(GO:0003094) renal filtration(GO:0097205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	5.9	GO:0005588	collagen type V trimer(GO:0005588)
1.7	10.3	GO:1990584	cardiac Troponin complex(GO:1990584)
1.4	24.8	GO:0005861	troponin complex(GO:0005861)
1.3	5.1	GO:0030314	junctional membrane complex(GO:0030314)
1.1	6.8	GO:0005927	muscle tendon junction(GO:0005927)
0.8	2.5	GO:0034680	integrin alpha10-beta1 complex(GO:0034680)
0.6	2.5	GO:0045160	myosin I complex(GO:0045160)
0.6	21.5	GO:0005859	muscle myosin complex(GO:0005859)
0.5	3.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.5	5.0	GO:0097512	cardiac myofibril(GO:0097512)
0.3	2.6	GO:0016012	sarcoglycan complex(GO:0016012)
0.3	8.2	GO:0031143	pseudopodium(GO:0031143)
0.3	1.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.3	2.5	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.3	1.3	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.2	2.5	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.2	GO:0016589	NURF complex(GO:0016589)
0.2	1.2	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.2	0.5	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	22.4	GO:0030018	Z disc(GO:0030018)
0.1	1.0	GO:0035976	AP1 complex(GO:0035976)
0.1	4.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.5	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.1	3.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	1.8	GO:0044291	cell-cell contact zone(GO:0044291)
0.1	0.7	GO:0005638	lamin filament(GO:0005638)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	1.6	GO:0071564	npBAF complex(GO:0071564)
0.1	1.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	1.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.9	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	4.6	GO:0005901	caveola(GO:0005901)
0.0	0.7	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	1.3	GO:0097546	ciliary base(GO:0097546)
0.0	2.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.4	GO:0097470	ribbon synapse(GO:0097470)
0.0	4.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	4.0	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.8	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.5	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	1.6	GO:0005604	basement membrane(GO:0005604)
0.0	0.7	GO:0016528	sarcoplasm(GO:0016528)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	5.6	GO:0016607	nuclear speck(GO:0016607)
0.0	0.3	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.7	GO:0031526	brush border membrane(GO:0031526)
0.0	3.0	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.0	GO:0071159	NF-kappaB complex(GO:0071159)
0.0	0.7	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	2.5	GO:0005802	trans-Golgi network(GO:0005802)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	48.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.4	3.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	4.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	10.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	4.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	2.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	3.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.1	4.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	1.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	2.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	3.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	14.5	GO:0031013	troponin I binding(GO:0031013)
1.0	3.1	GO:0033823	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.8	4.1	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.8	2.4	GO:0051373	FATZ binding(GO:0051373)
0.7	2.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.6	3.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6	1.8	GO:0070538	oleic acid binding(GO:0070538)
0.5	18.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.5	2.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.5	3.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.5	2.5	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.5	2.8	GO:0017018	myosin phosphatase activity(GO:0017018)
0.5	10.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	1.3	GO:1904288	BAT3 complex binding(GO:1904288)
0.4	1.4	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.3	3.7	GO:0031014	troponin T binding(GO:0031014)
0.3	0.8	GO:0019959	interleukin-8 binding(GO:0019959)
0.3	1.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.2	18.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	0.6	GO:0046848	hydroxyapatite binding(GO:0046848)
0.2	3.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	1.2	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1	2.5	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	1.2	GO:0036310	annealing helicase activity(GO:0036310)
0.1	1.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	9.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	1.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	0.5	GO:0047298	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1	0.8	GO:0001515	opioid peptide activity(GO:0001515)
0.1	3.5	GO:0004629	phospholipase C activity(GO:0004629)
0.1	0.7	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	0.6	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.1	0.5	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	1.0	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	1.1	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	10.2	GO:0046332	SMAD binding(GO:0046332)
0.1	3.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	1.3	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1	1.5	GO:0035198	miRNA binding(GO:0035198)
0.1	0.4	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1	0.3	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.4	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.3	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	0.8	GO:1990239	steroid hormone binding(GO:1990239)
0.1	1.1	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.4	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	4.7	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	22.8	GO:0003779	actin binding(GO:0003779)
0.0	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.0	2.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.6	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.7	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	1.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.8	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.9	GO:0070888	E-box binding(GO:0070888)
0.0	1.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.2	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	6.3	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.6	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	3.9	GO:0003924	GTPase activity(GO:0003924)
0.0	1.7	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.3	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.5	GO:0050681	androgen receptor binding(GO:0050681)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	6.8	NABA COLLAGENS	Genes encoding collagen proteins
0.1	19.7	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	2.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	3.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.9	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	3.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.7	PID FGF PATHWAY	FGF signaling pathway
0.0	1.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	2.1	PID AURORA B PATHWAY	Aurora B signaling
0.0	2.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	1.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	1.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	3.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.5	PID FOXO PATHWAY	FoxO family signaling
0.0	3.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	4.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling