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ENCODE cell lines, expression (Ernst 2011)

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Results for NFAT5

Z-value: 1.03

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Transcription factors associated with NFAT5

Gene Symbol Gene ID Gene Info
NFAT5
ENSG00000102908.16 NFAT5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFAT5hg19_v2_chr16_+_69600209_696002540.155.7e-01Click!

Activity profile of NFAT5 motif

Sorted Z-values of NFAT5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFAT5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_47579188 3.35 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
 TNS3
 tensin 3
chr1_-_153517473 3.11 ENST00000368715.1
 S100A4
 S100 calcium binding protein A4
chr1_-_57045228 2.76 ENST00000371250.3
 PPAP2B
 phosphatidic acid phosphatase type 2B
chr6_+_86159821 2.66 ENST00000369651.3
 NT5E
 5'-nucleotidase, ecto (CD73)
chr12_+_26274917 2.65 ENST00000538142.1
 SSPN
 sarcospan
chr11_-_111794446 2.15 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr14_-_25479811 2.10 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr14_-_30396948 1.97 ENST00000331968.5
 PRKD1
 protein kinase D1
chr11_+_12399071 1.51 ENST00000539723.1
ENST00000550549.1
 PARVA
 parvin, alpha
chr3_+_8543393 1.51 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
 LMCD1
 LIM and cysteine-rich domains 1
chr14_-_102706934 1.49 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
 MOK
 MOK protein kinase
chr3_+_8543561 1.44 ENST00000397386.3
 LMCD1
 LIM and cysteine-rich domains 1
chr13_-_67804445 1.43 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
 PCDH9
 protocadherin 9
chr1_-_201346761 1.41 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
 TNNT2
 troponin T type 2 (cardiac)
chr11_+_19799327 1.40 ENST00000540292.1
 NAV2
 neuron navigator 2
chr8_-_49833978 1.39 ENST00000020945.1
 SNAI2
 snail family zinc finger 2
chr10_+_89419370 1.35 ENST00000361175.4
ENST00000456849.1
 PAPSS2
 3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_+_19798964 1.35 ENST00000527559.2
 NAV2
 neuron navigator 2
chr11_+_131240373 1.29 ENST00000374791.3
ENST00000436745.1
 NTM
 neurotrimin
chr5_-_150521192 1.19 ENST00000523714.1
ENST00000521749.1
 ANXA6
 annexin A6
chr7_+_128399002 1.12 ENST00000493278.1
 CALU
 calumenin
chr2_-_162931052 1.11 ENST00000360534.3
 DPP4
 dipeptidyl-peptidase 4
chr3_+_8543533 1.03 ENST00000454244.1
 LMCD1
 LIM and cysteine-rich domains 1
chr18_-_33702078 1.02 ENST00000586829.1
 SLC39A6
 solute carrier family 39 (zinc transporter), member 6
chr12_+_10365404 0.98 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
 GABARAPL1
 GABA(A) receptor-associated protein like 1
chr11_+_131781290 0.94 ENST00000425719.2
ENST00000374784.1
 NTM
 neurotrimin
chr7_+_65670186 0.83 ENST00000304842.5
ENST00000442120.1
 TPST1
 tyrosylprotein sulfotransferase 1
chr8_-_27469196 0.72 ENST00000546343.1
ENST00000560566.1
 CLU
 clusterin
chr4_-_76861392 0.70 ENST00000505594.1
 NAAA
 N-acylethanolamine acid amidase
chr3_-_47950745 0.66 ENST00000429422.1
 MAP4
 microtubule-associated protein 4
chr6_-_131291572 0.63 ENST00000529208.1
 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
chr9_-_13175823 0.63 ENST00000545857.1
 MPDZ
 multiple PDZ domain protein
chr4_-_74847800 0.62 ENST00000296029.3
 PF4
 platelet factor 4
chr4_+_71587669 0.62 ENST00000381006.3
ENST00000226328.4
 RUFY3
 RUN and FYVE domain containing 3
chr3_+_49027308 0.58 ENST00000383729.4
ENST00000343546.4
 P4HTM
 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr6_+_89790459 0.57 ENST00000369472.1
 PNRC1
 proline-rich nuclear receptor coactivator 1
chrX_+_37208540 0.57 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
 PRRG1
TM4SF2
 proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr19_+_17420340 0.55 ENST00000359866.4
 DDA1
 DET1 and DDB1 associated 1
chr4_+_26322185 0.55 ENST00000361572.6
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr1_-_115300579 0.54 ENST00000358528.4
ENST00000525132.1
 CSDE1
 cold shock domain containing E1, RNA-binding
chr16_+_89988259 0.53 ENST00000554444.1
ENST00000556565.1
 TUBB3
 Tubulin beta-3 chain
chr6_-_134495992 0.52 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
 SGK1
 serum/glucocorticoid regulated kinase 1
chrX_+_37208521 0.50 ENST00000378628.4
 PRRG1
 proline rich Gla (G-carboxyglutamic acid) 1
chr12_-_123756781 0.49 ENST00000544658.1
 CDK2AP1
 cyclin-dependent kinase 2 associated protein 1
chr1_-_115300592 0.48 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
 CSDE1
 cold shock domain containing E1, RNA-binding
chr4_+_26322409 0.48 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr1_-_16345245 0.48 ENST00000311890.9
 HSPB7
 heat shock 27kDa protein family, member 7 (cardiovascular)
chr12_+_69139886 0.44 ENST00000398004.2
 SLC35E3
 solute carrier family 35, member E3
chr6_+_89790490 0.44 ENST00000336032.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr11_-_67120974 0.43 ENST00000539074.1
ENST00000312419.3
 POLD4
 polymerase (DNA-directed), delta 4, accessory subunit
chr15_+_49170083 0.43 ENST00000530028.2
 EID1
 EP300 interacting inhibitor of differentiation 1
chr19_+_48828582 0.40 ENST00000270221.6
ENST00000596315.1
 EMP3
 epithelial membrane protein 3
chr19_-_46285736 0.38 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
 DMPK
 dystrophia myotonica-protein kinase
chr5_-_77844974 0.35 ENST00000515007.2
 LHFPL2
 lipoma HMGIC fusion partner-like 2
chr20_+_33104199 0.33 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
 DYNLRB1
 dynein, light chain, roadblock-type 1
chr3_-_149293990 0.33 ENST00000472417.1
 WWTR1
 WW domain containing transcription regulator 1
chr14_+_100848311 0.32 ENST00000542471.2
 WDR25
 WD repeat domain 25
chr7_-_100888337 0.29 ENST00000223136.4
 FIS1
 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr13_-_24463530 0.28 ENST00000382172.3
 MIPEP
 mitochondrial intermediate peptidase
chr14_+_73704201 0.28 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
 PAPLN
 papilin, proteoglycan-like sulfated glycoprotein
chr19_+_48828788 0.27 ENST00000594198.1
ENST00000597279.1
ENST00000593437.1
 EMP3
 epithelial membrane protein 3
chrX_-_41782592 0.27 ENST00000378158.1
 CASK
 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr11_+_8932828 0.26 ENST00000530281.1
ENST00000396648.2
ENST00000534147.1
ENST00000529942.1
 AKIP1
 A kinase (PRKA) interacting protein 1
chr1_+_18958008 0.26 ENST00000420770.2
ENST00000400661.3
 PAX7
 paired box 7
chr20_-_23731893 0.26 ENST00000398402.1
 CST1
 cystatin SN
chr17_+_18684563 0.26 ENST00000476139.1
 TVP23B
 trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr1_-_243418344 0.25 ENST00000366542.1
 CEP170
 centrosomal protein 170kDa
chr15_+_49170281 0.25 ENST00000560490.1
 EID1
 EP300 interacting inhibitor of differentiation 1
chrX_+_12993202 0.24 ENST00000451311.2
ENST00000380636.1
 TMSB4X
 thymosin beta 4, X-linked
chr7_-_100888313 0.23 ENST00000442303.1
 FIS1
 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
chr11_+_119039414 0.22 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
 NLRX1
 NLR family member X1
chr17_+_68071458 0.21 ENST00000589377.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr12_-_54813229 0.20 ENST00000293379.4
 ITGA5
 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_+_42212526 0.20 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
 CEA
CEACAM5
 Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr9_-_14314518 0.19 ENST00000397581.2
 NFIB
 nuclear factor I/B
chr10_-_124639062 0.19 ENST00000368898.3
ENST00000368896.1
ENST00000545804.1
 FAM24B
CUZD1
 family with sequence similarity 24, member B
CUB and zona pellucida-like domains 1
chr5_-_137090028 0.18 ENST00000314940.4
 HNRNPA0
 heterogeneous nuclear ribonucleoprotein A0
chr3_-_49131013 0.17 ENST00000424300.1
 QRICH1
 glutamine-rich 1
chr19_+_45254529 0.16 ENST00000444487.1
 BCL3
 B-cell CLL/lymphoma 3
chr3_-_9834375 0.16 ENST00000343450.2
ENST00000301964.2
 TADA3
 transcriptional adaptor 3
chr17_-_15466742 0.13 ENST00000584811.1
ENST00000419890.2
 TVP23C
 trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr4_+_71588372 0.13 ENST00000536664.1
 RUFY3
 RUN and FYVE domain containing 3
chr12_+_110011571 0.13 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
 MVK
 mevalonate kinase
chr20_-_23807358 0.12 ENST00000304725.2
 CST2
 cystatin SA
chr20_-_23731569 0.12 ENST00000304749.2
 CST1
 cystatin SN
chr17_-_40950698 0.11 ENST00000328434.7
 COA3
 cytochrome c oxidase assembly factor 3
chr18_-_52989217 0.11 ENST00000570287.2
 TCF4
 transcription factor 4
chr17_+_68071389 0.11 ENST00000283936.1
ENST00000392671.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr12_-_10955226 0.11 ENST00000240687.2
 TAS2R7
 taste receptor, type 2, member 7
chr18_-_52989525 0.10 ENST00000457482.3
 TCF4
 transcription factor 4
chr13_+_45694583 0.09 ENST00000340473.6
 GTF2F2
 general transcription factor IIF, polypeptide 2, 30kDa
chr12_+_69186125 0.09 ENST00000399333.3
 AC124890.1
 HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr19_+_49999631 0.07 ENST00000270625.2
ENST00000596873.1
ENST00000594493.1
ENST00000599561.1
 RPS11
 ribosomal protein S11
chrX_+_135579670 0.07 ENST00000218364.4
 HTATSF1
 HIV-1 Tat specific factor 1
chr6_-_31926208 0.07 ENST00000454913.1
ENST00000436289.2
 NELFE
 negative elongation factor complex member E
chr17_+_38083977 0.06 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
 RP11-387H17.4
 RP11-387H17.4
chr17_-_15466850 0.06 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
 TVP23C
TVP23C-CDRT4
 trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr8_-_99954788 0.06 ENST00000523601.1
 STK3
 serine/threonine kinase 3
chr12_+_101988627 0.06 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
 MYBPC1
 myosin binding protein C, slow type
chr3_-_48594248 0.05 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
 PFKFB4
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr1_-_6259641 0.05 ENST00000234875.4
 RPL22
 ribosomal protein L22
chrX_-_41782249 0.04 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
 CASK
 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr7_+_1127723 0.03 ENST00000397088.3
 GPER1
 G protein-coupled estrogen receptor 1
chr4_-_83483395 0.03 ENST00000515780.2
 TMEM150C
 transmembrane protein 150C
chr11_-_8190534 0.03 ENST00000309737.6
ENST00000425599.2
ENST00000539720.1
ENST00000531450.1
ENST00000419822.2
ENST00000335425.7
ENST00000343202.4
 RIC3
 RIC3 acetylcholine receptor chaperone
chr7_+_120969045 0.03 ENST00000222462.2
 WNT16
 wingless-type MMTV integration site family, member 16
chr2_+_200820494 0.03 ENST00000435773.2
 C2orf47
 chromosome 2 open reading frame 47
chr9_-_34589700 0.02 ENST00000351266.4
 CNTFR
 ciliary neurotrophic factor receptor
chr5_-_35230434 0.02 ENST00000504500.1
 PRLR
 prolactin receptor
chr22_-_44208070 0.02 ENST00000396231.2
 EFCAB6
 EF-hand calcium binding domain 6
chr3_+_185000729 0.02 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
chr16_+_2079637 0.02 ENST00000561844.1
 SLC9A3R2
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr16_+_10971037 0.01 ENST00000324288.8
ENST00000381835.5
 CIITA
 class II, major histocompatibility complex, transactivator
chr7_+_95401851 0.01 ENST00000447467.2
 DYNC1I1
 dynein, cytoplasmic 1, intermediate chain 1
chr4_+_74718906 0.01 ENST00000226524.3
 PF4V1
 platelet factor 4 variant 1
chr16_+_2079501 0.00 ENST00000563587.1
 SLC9A3R2
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr16_-_67514982 0.00 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
 ATP6V0D1
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr10_-_135122603 0.00 ENST00000368563.2
 TUBGCP2
 tubulin, gamma complex associated protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0021564 vagus nerve development(GO:0021564)
0.7 2.7 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.5 1.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4 1.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.3 1.0 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3 1.4 GO:0000103 sulfate assimilation(GO:0000103)
0.3 2.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 0.8 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 1.1 GO:0036343 psychomotor behavior(GO:0036343)
0.2 2.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 1.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 4.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.7 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 2.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.5 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 3.3 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 1.2 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.6 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.7 GO:0032060 bleb assembly(GO:0032060)
0.0 2.0 GO:0008038 neuron recognition(GO:0008038)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:2000790 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 3.1 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 4.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 0.8 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 2.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.4 GO:0030172 troponin C binding(GO:0030172)
0.2 3.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.1 2.0 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 2.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.6 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.2 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 2.2 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.1 2.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 1.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.7 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 1.0 GO:0044291 cell-cell contact zone(GO:0044291)