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ENCODE cell lines, expression (Ernst 2011)

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Results for NFATC1

Z-value: 1.41

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Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
NFATC1
ENSG00000131196.13 NFATC1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC1hg19_v2_chr18_+_77155856_771559390.194.8e-01Click!

Activity profile of NFATC1 motif

Sorted Z-values of NFATC1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_35691017 4.17 ENST00000378292.3
 TPM2
 tropomyosin 2 (beta)
chr3_-_127541194 4.16 ENST00000453507.2
 MGLL
 monoglyceride lipase
chr1_-_153517473 4.15 ENST00000368715.1
 S100A4
 S100 calcium binding protein A4
chr3_-_158390282 3.07 ENST00000264265.3
 LXN
 latexin
chr11_-_102668879 2.99 ENST00000315274.6
 MMP1
 matrix metallopeptidase 1 (interstitial collagenase)
chr18_-_53177984 2.88 ENST00000543082.1
 TCF4
 transcription factor 4
chr18_-_53257027 2.82 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
 TCF4
 transcription factor 4
chr12_-_50616122 2.80 ENST00000552823.1
ENST00000552909.1
 LIMA1
 LIM domain and actin binding 1
chr17_-_39780819 2.80 ENST00000311208.8
 KRT17
 keratin 17
chr12_-_50616382 2.72 ENST00000552783.1
 LIMA1
 LIM domain and actin binding 1
chr22_+_38071615 2.53 ENST00000215909.5
 LGALS1
 lectin, galactoside-binding, soluble, 1
chr1_+_86046433 2.50 ENST00000451137.2
 CYR61
 cysteine-rich, angiogenic inducer, 61
chr12_-_52887034 2.40 ENST00000330722.6
 KRT6A
 keratin 6A
chr3_+_69134080 2.33 ENST00000273258.3
 ARL6IP5
 ADP-ribosylation-like factor 6 interacting protein 5
chr1_-_226926864 2.32 ENST00000429204.1
ENST00000366784.1
 ITPKB
 inositol-trisphosphate 3-kinase B
chr13_+_73629107 2.29 ENST00000539231.1
 KLF5
 Kruppel-like factor 5 (intestinal)
chr3_+_69134124 2.23 ENST00000478935.1
 ARL6IP5
 ADP-ribosylation-like factor 6 interacting protein 5
chr18_-_53089723 2.08 ENST00000561992.1
ENST00000562512.2
 TCF4
 transcription factor 4
chr2_+_189839046 2.07 ENST00000304636.3
ENST00000317840.5
 COL3A1
 collagen, type III, alpha 1
chr1_+_79115503 1.93 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
 IFI44
 interferon-induced protein 44
chr4_-_72649763 1.90 ENST00000513476.1
 GC
 group-specific component (vitamin D binding protein)
chr1_-_186649543 1.90 ENST00000367468.5
 PTGS2
 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chrX_-_13835147 1.89 ENST00000493677.1
ENST00000355135.2
 GPM6B
 glycoprotein M6B
chr1_+_46640750 1.89 ENST00000372003.1
 TSPAN1
 tetraspanin 1
chr11_-_122930121 1.88 ENST00000524552.1
 HSPA8
 heat shock 70kDa protein 8
chr12_+_96588143 1.87 ENST00000228741.3
ENST00000547249.1
 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
chr3_-_107777208 1.80 ENST00000398258.3
 CD47
 CD47 molecule
chr17_-_39743139 1.78 ENST00000167586.6
 KRT14
 keratin 14
chr9_-_14314518 1.74 ENST00000397581.2
 NFIB
 nuclear factor I/B
chr3_-_111314230 1.71 ENST00000317012.4
 ZBED2
 zinc finger, BED-type containing 2
chr5_+_140729649 1.71 ENST00000523390.1
 PCDHGB1
 protocadherin gamma subfamily B, 1
chr10_+_11206925 1.69 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
 CELF2
 CUGBP, Elav-like family member 2
chr9_-_14314566 1.68 ENST00000397579.2
 NFIB
 nuclear factor I/B
chr17_-_39677971 1.66 ENST00000393976.2
 KRT15
 keratin 15
chr10_-_121296045 1.61 ENST00000392865.1
 RGS10
 regulator of G-protein signaling 10
chr1_-_94703118 1.49 ENST00000260526.6
ENST00000370217.3
 ARHGAP29
 Rho GTPase activating protein 29
chr5_-_94417339 1.46 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
 MCTP1
 multiple C2 domains, transmembrane 1
chr4_+_146403912 1.45 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
 SMAD1
 SMAD family member 1
chrX_-_10544942 1.41 ENST00000380779.1
 MID1
 midline 1 (Opitz/BBB syndrome)
chr11_-_122929699 1.40 ENST00000526686.1
 HSPA8
 heat shock 70kDa protein 8
chr17_+_32582293 1.38 ENST00000580907.1
ENST00000225831.4
 CCL2
 chemokine (C-C motif) ligand 2
chr18_-_52989217 1.38 ENST00000570287.2
 TCF4
 transcription factor 4
chr10_-_105212059 1.37 ENST00000260743.5
 CALHM2
 calcium homeostasis modulator 2
chr18_-_52989525 1.35 ENST00000457482.3
 TCF4
 transcription factor 4
chr2_-_161349909 1.30 ENST00000392753.3
 RBMS1
 RNA binding motif, single stranded interacting protein 1
chr6_-_32920794 1.28 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
 HLA-DMA
XXbac-BPG181M17.5
 major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chrX_+_102611373 1.24 ENST00000372661.3
ENST00000372656.3
 WBP5
 WW domain binding protein 5
chr8_+_95653302 1.24 ENST00000423620.2
ENST00000433389.2
 ESRP1
 epithelial splicing regulatory protein 1
chr5_+_49963239 1.24 ENST00000505554.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr8_+_95653427 1.24 ENST00000454170.2
 ESRP1
 epithelial splicing regulatory protein 1
chr10_-_105212141 1.23 ENST00000369788.3
 CALHM2
 calcium homeostasis modulator 2
chr4_-_71532339 1.22 ENST00000254801.4
 IGJ
 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr8_+_95653373 1.21 ENST00000358397.5
 ESRP1
 epithelial splicing regulatory protein 1
chr10_+_13141441 1.20 ENST00000263036.5
 OPTN
 optineurin
chr7_+_134551583 1.20 ENST00000435928.1
 CALD1
 caldesmon 1
chr5_+_140762268 1.19 ENST00000518325.1
 PCDHGA7
 protocadherin gamma subfamily A, 7
chr1_-_103574024 1.19 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
 COL11A1
 collagen, type XI, alpha 1
chr1_-_111743285 1.17 ENST00000357640.4
 DENND2D
 DENN/MADD domain containing 2D
chr11_+_131240373 1.17 ENST00000374791.3
ENST00000436745.1
 NTM
 neurotrimin
chr17_-_29648761 1.15 ENST00000247270.3
ENST00000462804.2
 EVI2A
 ecotropic viral integration site 2A
chr6_+_32407619 1.14 ENST00000395388.2
ENST00000374982.5
 HLA-DRA
 major histocompatibility complex, class II, DR alpha
chr12_-_91573249 1.12 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
 DCN
 decorin
chr14_-_30396802 1.10 ENST00000415220.2
 PRKD1
 protein kinase D1
chr16_+_15528332 1.07 ENST00000566490.1
 C16orf45
 chromosome 16 open reading frame 45
chr10_+_103825080 1.05 ENST00000299238.5
 HPS6
 Hermansky-Pudlak syndrome 6
chr5_+_49962495 1.05 ENST00000515175.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr12_-_91573316 1.05 ENST00000393155.1
 DCN
 decorin
chr2_-_211168332 1.04 ENST00000341685.4
 MYL1
 myosin, light chain 1, alkali; skeletal, fast
chr11_-_102651343 1.03 ENST00000279441.4
ENST00000539681.1
 MMP10
 matrix metallopeptidase 10 (stromelysin 2)
chr9_+_124062071 1.03 ENST00000373818.4
 GSN
 gelsolin
chr2_+_33701286 1.02 ENST00000403687.3
 RASGRP3
 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr8_+_70404996 1.02 ENST00000402687.4
ENST00000419716.3
 SULF1
 sulfatase 1
chr11_-_14358620 1.00 ENST00000531421.1
 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
chr10_+_13141585 0.99 ENST00000378764.2
 OPTN
 optineurin
chr9_-_16870704 0.98 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
 BNC2
 basonuclin 2
chr5_+_49962772 0.98 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr5_-_88179302 0.96 ENST00000504921.2
 MEF2C
 myocyte enhancer factor 2C
chr2_-_211179883 0.95 ENST00000352451.3
 MYL1
 myosin, light chain 1, alkali; skeletal, fast
chr10_+_13142075 0.94 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
 OPTN
 optineurin
chr3_+_88188254 0.93 ENST00000309495.5
 ZNF654
 zinc finger protein 654
chr1_+_218519577 0.92 ENST00000366930.4
ENST00000366929.4
 TGFB2
 transforming growth factor, beta 2
chr12_+_54447637 0.90 ENST00000609810.1
ENST00000430889.2
 HOXC4
HOXC4
 homeobox C4
Homeobox protein Hox-C4
chr6_-_134495992 0.89 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
 SGK1
 serum/glucocorticoid regulated kinase 1
chr15_+_33010175 0.88 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
 GREM1
 gremlin 1, DAN family BMP antagonist
chr22_-_19512893 0.88 ENST00000403084.1
ENST00000413119.2
 CLDN5
 claudin 5
chr19_+_10197463 0.87 ENST00000590378.1
ENST00000397881.3
 C19orf66
 chromosome 19 open reading frame 66
chr5_+_140810132 0.87 ENST00000252085.3
 PCDHGA12
 protocadherin gamma subfamily A, 12
chr15_+_52155001 0.80 ENST00000544199.1
 TMOD3
 tropomodulin 3 (ubiquitous)
chr12_-_91573132 0.80 ENST00000550563.1
ENST00000546370.1
 DCN
 decorin
chr3_+_133293278 0.78 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
 CDV3
 CDV3 homolog (mouse)
chr5_+_148521136 0.78 ENST00000506113.1
 ABLIM3
 actin binding LIM protein family, member 3
chr5_+_148521046 0.78 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
 ABLIM3
 actin binding LIM protein family, member 3
chrX_-_13835461 0.77 ENST00000316715.4
ENST00000356942.5
 GPM6B
 glycoprotein M6B
chr14_+_90864504 0.77 ENST00000544280.2
 CALM1
 calmodulin 1 (phosphorylase kinase, delta)
chr4_-_159094194 0.76 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
 FAM198B
 family with sequence similarity 198, member B
chr6_+_129204337 0.74 ENST00000421865.2
 LAMA2
 laminin, alpha 2
chr8_-_122653630 0.74 ENST00000303924.4
 HAS2
 hyaluronan synthase 2
chr20_-_14318248 0.72 ENST00000378053.3
ENST00000341420.4
 FLRT3
 fibronectin leucine rich transmembrane protein 3
chr9_+_27109133 0.72 ENST00000519097.1
ENST00000380036.4
 TEK
 TEK tyrosine kinase, endothelial
chr14_-_92413353 0.71 ENST00000556154.1
 FBLN5
 fibulin 5
chr10_-_92681033 0.71 ENST00000371697.3
 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
chr4_+_41614909 0.71 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
 LIMCH1
 LIM and calponin homology domains 1
chr12_+_96588279 0.70 ENST00000552142.1
 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
chr4_+_26585686 0.70 ENST00000505206.1
ENST00000511789.1
 TBC1D19
 TBC1 domain family, member 19
chr7_+_107220422 0.70 ENST00000005259.4
 BCAP29
 B-cell receptor-associated protein 29
chr11_-_111794446 0.69 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr15_-_43785303 0.69 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
 TP53BP1
 tumor protein p53 binding protein 1
chr3_-_136471204 0.69 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
 STAG1
 stromal antigen 1
chr2_+_234668894 0.69 ENST00000305208.5
ENST00000608383.1
ENST00000360418.3
 UGT1A8
UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_162602244 0.69 ENST00000367922.3
ENST00000367921.3
 DDR2
 discoidin domain receptor tyrosine kinase 2
chr4_-_38806404 0.68 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
 TLR1
 toll-like receptor 1
chr15_+_63354769 0.66 ENST00000558910.1
 TPM1
 tropomyosin 1 (alpha)
chr16_+_1583567 0.65 ENST00000566264.1
 TMEM204
 transmembrane protein 204
chr20_+_36149602 0.65 ENST00000062104.2
ENST00000346199.2
 NNAT
 neuronatin
chr4_-_11431389 0.65 ENST00000002596.5
 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr4_-_104021009 0.64 ENST00000509245.1
ENST00000296424.4
 BDH2
 3-hydroxybutyrate dehydrogenase, type 2
chr14_-_30396948 0.64 ENST00000331968.5
 PRKD1
 protein kinase D1
chr18_+_29027696 0.64 ENST00000257189.4
 DSG3
 desmoglein 3
chr12_-_28125638 0.61 ENST00000545234.1
 PTHLH
 parathyroid hormone-like hormone
chr20_+_55204351 0.58 ENST00000201031.2
 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_-_102401469 0.58 ENST00000260227.4
 MMP7
 matrix metallopeptidase 7 (matrilysin, uterine)
chr1_+_209941942 0.58 ENST00000487271.1
ENST00000477431.1
 TRAF3IP3
 TRAF3 interacting protein 3
chr11_-_110167352 0.58 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
 RDX
 radixin
chr13_-_67804445 0.56 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
 PCDH9
 protocadherin 9
chr1_-_150780757 0.56 ENST00000271651.3
 CTSK
 cathepsin K
chr5_-_73937244 0.55 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
 ENC1
 ectodermal-neural cortex 1 (with BTB domain)
chr6_-_136871957 0.54 ENST00000354570.3
 MAP7
 microtubule-associated protein 7
chr10_-_27149851 0.53 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
 ABI1
 abl-interactor 1
chr3_+_130569592 0.53 ENST00000533801.2
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr11_-_2182388 0.53 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
 INS
INS-IGF2
 insulin
INS-IGF2 readthrough
chr5_+_135394840 0.50 ENST00000503087.1
 TGFBI
 transforming growth factor, beta-induced, 68kDa
chr12_-_52685312 0.49 ENST00000327741.5
 KRT81
 keratin 81
chr12_+_20968608 0.48 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
 LST3
SLCO1B3
SLCO1B7
 Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr3_+_132316081 0.48 ENST00000249887.2
 ACKR4
 atypical chemokine receptor 4
chr4_+_154387480 0.48 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
 KIAA0922
 KIAA0922
chr6_-_128841503 0.48 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
 PTPRK
 protein tyrosine phosphatase, receptor type, K
chr5_-_111093759 0.47 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
 NREP
 neuronal regeneration related protein
chr10_-_27149792 0.47 ENST00000376140.3
ENST00000376170.4
 ABI1
 abl-interactor 1
chr12_+_27396901 0.46 ENST00000541191.1
ENST00000389032.3
 STK38L
 serine/threonine kinase 38 like
chr7_+_55177416 0.45 ENST00000450046.1
ENST00000454757.2
 EGFR
 epidermal growth factor receptor
chrX_+_152760397 0.45 ENST00000331595.4
ENST00000431891.1
 BGN
 biglycan
chr9_-_20622478 0.44 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_-_123756781 0.44 ENST00000544658.1
 CDK2AP1
 cyclin-dependent kinase 2 associated protein 1
chr10_+_104535994 0.42 ENST00000369889.4
 WBP1L
 WW domain binding protein 1-like
chr11_-_27723158 0.41 ENST00000395980.2
 BDNF
 brain-derived neurotrophic factor
chr10_-_27149904 0.41 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
 ABI1
 abl-interactor 1
chr3_-_27498235 0.40 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
 SLC4A7
 solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr10_+_71561630 0.40 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
 COL13A1
 collagen, type XIII, alpha 1
chr8_-_95274536 0.40 ENST00000297596.2
ENST00000396194.2
 GEM
 GTP binding protein overexpressed in skeletal muscle
chr15_-_59981479 0.40 ENST00000607373.1
 BNIP2
 BCL2/adenovirus E1B 19kDa interacting protein 2
chr12_-_123756687 0.39 ENST00000261692.2
 CDK2AP1
 cyclin-dependent kinase 2 associated protein 1
chr1_-_43638168 0.38 ENST00000431635.2
 EBNA1BP2
 EBNA1 binding protein 2
chr10_+_105036909 0.38 ENST00000369849.4
 INA
 internexin neuronal intermediate filament protein, alpha
chr12_+_32260085 0.37 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
 BICD1
 bicaudal D homolog 1 (Drosophila)
chr15_+_23255242 0.37 ENST00000450802.3
 GOLGA8I
 golgin A8 family, member I
chr12_-_16759711 0.37 ENST00000447609.1
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr3_+_130569429 0.37 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr13_-_108867101 0.36 ENST00000356922.4
 LIG4
 ligase IV, DNA, ATP-dependent
chr14_-_51562745 0.36 ENST00000298355.3
 TRIM9
 tripartite motif containing 9
chr12_+_131356582 0.35 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
 RAN
 RAN, member RAS oncogene family
chr5_+_32788945 0.35 ENST00000326958.1
 AC026703.1
 AC026703.1
chr1_+_244214577 0.34 ENST00000358704.4
 ZBTB18
 zinc finger and BTB domain containing 18
chr14_-_107013465 0.33 ENST00000390625.2
 IGHV3-49
 immunoglobulin heavy variable 3-49
chr1_+_86934526 0.33 ENST00000394711.1
 CLCA1
 chloride channel accessory 1
chr3_-_119813264 0.32 ENST00000264235.8
 GSK3B
 glycogen synthase kinase 3 beta
chr1_+_203734296 0.32 ENST00000442561.2
ENST00000367217.5
 LAX1
 lymphocyte transmembrane adaptor 1
chr6_+_63921351 0.31 ENST00000370659.1
 FKBP1C
 FK506 binding protein 1C
chr9_-_215744 0.30 ENST00000382387.2
 C9orf66
 chromosome 9 open reading frame 66
chr7_-_22862406 0.30 ENST00000372879.4
 TOMM7
 translocase of outer mitochondrial membrane 7 homolog (yeast)
chr12_-_7656357 0.29 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
 CD163
 CD163 molecule
chr10_+_128593978 0.29 ENST00000280333.6
 DOCK1
 dedicator of cytokinesis 1
chr1_-_159684371 0.29 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
 CRP
 C-reactive protein, pentraxin-related
chr4_-_178363581 0.28 ENST00000264595.2
 AGA
 aspartylglucosaminidase
chr1_-_155880672 0.28 ENST00000609492.1
ENST00000368322.3
 RIT1
 Ras-like without CAAX 1
chr12_+_104359641 0.28 ENST00000537100.1
 TDG
 thymine-DNA glycosylase
chr3_+_152017360 0.27 ENST00000485910.1
ENST00000463374.1
 MBNL1
 muscleblind-like splicing regulator 1
chr22_-_41215291 0.26 ENST00000542412.1
ENST00000544408.1
 SLC25A17
 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr17_+_27047570 0.26 ENST00000472628.1
ENST00000578181.1
 RPL23A
 ribosomal protein L23a
chrX_-_63005405 0.25 ENST00000374878.1
ENST00000437457.2
 ARHGEF9
 Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_+_234580499 0.25 ENST00000354728.4
 UGT1A9
 UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_+_234580525 0.25 ENST00000609637.1
 UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_92632542 0.25 ENST00000409154.4
ENST00000370378.4
 KIAA1107
 KIAA1107
chr7_-_44530479 0.24 ENST00000355451.7
 NUDCD3
 NudC domain containing 3
chr3_+_46395219 0.24 ENST00000445132.2
ENST00000292301.4
 CCR2
 chemokine (C-C motif) receptor 2
chr13_-_49975632 0.23 ENST00000457041.1
ENST00000355854.4
 CAB39L
 calcium binding protein 39-like
chr18_+_61575200 0.23 ENST00000238508.3
 SERPINB10
 serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr7_-_83824169 0.23 ENST00000265362.4
 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_36986534 0.23 ENST00000429976.2
ENST00000301807.6
 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
chr12_+_26111823 0.22 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr1_+_948803 0.22 ENST00000379389.4
 ISG15
 ISG15 ubiquitin-like modifier
chr19_-_2427863 0.22 ENST00000215570.3
 TIMM13
 translocase of inner mitochondrial membrane 13 homolog (yeast)
chr14_-_92413727 0.21 ENST00000267620.10
 FBLN5
 fibulin 5
chr12_-_13529642 0.21 ENST00000318426.2
 C12orf36
 chromosome 12 open reading frame 36
chr12_+_98987369 0.20 ENST00000401722.3
ENST00000188376.5
ENST00000228318.3
ENST00000551917.1
ENST00000548046.1
ENST00000552981.1
ENST00000551265.1
ENST00000550695.1
ENST00000547534.1
ENST00000549338.1
ENST00000548847.1
 SLC25A3
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr22_-_41215328 0.20 ENST00000434185.1
ENST00000435456.2
 SLC25A17
 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr2_-_228244013 0.20 ENST00000304568.3
 TM4SF20
 transmembrane 4 L six family member 20
chr9_+_27109392 0.20 ENST00000406359.4
 TEK
 TEK tyrosine kinase, endothelial
chr20_-_50808236 0.20 ENST00000361387.2
 ZFP64
 ZFP64 zinc finger protein
chr12_+_104359614 0.20 ENST00000266775.9
ENST00000544861.1
 TDG
 thymine-DNA glycosylase
chr12_+_6644443 0.20 ENST00000396858.1
 GAPDH
 glyceraldehyde-3-phosphate dehydrogenase

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 4.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 3.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 4.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 6.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 3.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 2.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.8 10.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 1.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.5 2.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 1.9 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.4 2.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 4.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.9 GO:0005499 vitamin D binding(GO:0005499)
0.3 0.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 3.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 1.8 GO:1990254 keratin filament binding(GO:1990254)
0.3 1.9 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.7 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 0.6 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 2.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 4.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 0.5 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 3.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.5 GO:0051185 FAD transmembrane transporter activity(GO:0015230) coenzyme transporter activity(GO:0051185)
0.1 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 1.0 GO:0045159 myosin II binding(GO:0045159)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 5.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 3.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 7.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 2.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.7 GO:0004697 protein kinase C activity(GO:0004697)
0.1 6.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.3 GO:0033265 choline binding(GO:0033265)
0.1 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 4.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0015266 protein channel activity(GO:0015266)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 3.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.7 3.3 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.6 2.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.6 2.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6 4.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.5 3.4 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 1.9 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of platelet-derived growth factor production(GO:0090362) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.5 1.4 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.5 4.6 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.4 1.2 GO:0035989 tendon development(GO:0035989)
0.4 3.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 2.3 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.4 3.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.3 1.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.3 0.9 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 2.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.0 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.3 2.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 3.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.0 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 2.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.7 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 1.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.2 1.0 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 0.9 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 1.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.5 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.2 2.8 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 0.5 GO:0043132 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.1 0.4 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.9 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.9 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.4 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 3.1 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 6.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 0.4 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.5 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.6 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.7 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.7 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 3.0 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 1.7 GO:0008228 opsonization(GO:0008228)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 6.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.2 GO:2000439 monocyte extravasation(GO:0035696) negative regulation of eosinophil activation(GO:1902567) regulation of monocyte extravasation(GO:2000437) positive regulation of monocyte extravasation(GO:2000439)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.7 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.2 GO:0035606 induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.2 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.6 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.0 GO:0043586 tongue development(GO:0043586)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.2 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.4 GO:0045955 regulation of SNARE complex assembly(GO:0035542) negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 3.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 9.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.6 GO:0044849 estrous cycle(GO:0044849)
0.0 0.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.7 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 2.8 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0 1.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 4.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.0 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.9 GO:0050821 protein stabilization(GO:0050821)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 7.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 6.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 10.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.9 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 3.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 PID INSULIN PATHWAY Insulin Pathway
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.3 3.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 3.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 4.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 0.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 3.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 2.2 GO:0030478 actin cap(GO:0030478)
0.1 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.6 GO:0036021 endolysosome lumen(GO:0036021)
0.1 6.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.5 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.4 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 6.8 GO:0005882 intermediate filament(GO:0005882)
0.1 2.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.1 GO:0031082 BLOC complex(GO:0031082)
0.0 3.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 8.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 5.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.6 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.8 GO:0005604 basement membrane(GO:0005604)