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ENCODE cell lines, expression (Ernst 2011)

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Results for NKX2-2

Z-value: 0.47

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Transcription factors associated with NKX2-2

Gene Symbol Gene ID Gene Info
NKX2-2
ENSG00000125820.5 NKX2-2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-2hg19_v2_chr20_-_21494654_21494678-0.078.0e-01Click!

Activity profile of NKX2-2 motif

Sorted Z-values of NKX2-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_55888767 0.64 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr4_+_74269956 0.62 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
 ALB
 albumin
chr12_-_54689532 0.60 ENST00000540264.2
ENST00000312156.4
 NFE2
 nuclear factor, erythroid 2
chr1_-_227505289 0.52 ENST00000366765.3
 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
chrX_+_152953505 0.49 ENST00000253122.5
 SLC6A8
 solute carrier family 6 (neurotransmitter transporter), member 8
chr16_+_30212378 0.47 ENST00000569485.1
 SULT1A3
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr16_+_30212050 0.46 ENST00000563322.1
 SULT1A3
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr15_+_58702742 0.46 ENST00000356113.6
ENST00000414170.3
 LIPC
 lipase, hepatic
chr5_+_135394840 0.46 ENST00000503087.1
 TGFBI
 transforming growth factor, beta-induced, 68kDa
chr17_+_52978107 0.43 ENST00000445275.2
 TOM1L1
 target of myb1 (chicken)-like 1
chrX_+_115567767 0.40 ENST00000371900.4
 SLC6A14
 solute carrier family 6 (amino acid transporter), member 14
chr13_-_67802549 0.37 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr8_+_97597148 0.35 ENST00000521590.1
 SDC2
 syndecan 2
chr4_-_111563076 0.34 ENST00000354925.2
ENST00000511990.1
 PITX2
 paired-like homeodomain 2
chr17_+_53342311 0.33 ENST00000226067.5
 HLF
 hepatic leukemia factor
chr15_-_56209306 0.32 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr6_+_158733692 0.32 ENST00000367094.2
ENST00000367097.3
 TULP4
 tubby like protein 4
chr6_+_32121789 0.32 ENST00000437001.2
ENST00000375137.2
 PPT2
 palmitoyl-protein thioesterase 2
chr17_+_74372662 0.31 ENST00000591651.1
ENST00000545180.1
 SPHK1
 sphingosine kinase 1
chr9_-_99382065 0.30 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
 CDC14B
 cell division cycle 14B
chr2_+_170655322 0.29 ENST00000260956.4
ENST00000417292.1
 SSB
 Sjogren syndrome antigen B (autoantigen La)
chr1_+_54359854 0.29 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
 DIO1
 deiodinase, iodothyronine, type I
chr6_+_32121218 0.27 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
 PPT2
 palmitoyl-protein thioesterase 2
chr1_-_202936394 0.25 ENST00000367249.4
 CYB5R1
 cytochrome b5 reductase 1
chrX_-_154033661 0.24 ENST00000393531.1
 MPP1
 membrane protein, palmitoylated 1, 55kDa
chr12_-_28124903 0.24 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
 PTHLH
 parathyroid hormone-like hormone
chr5_+_108083517 0.24 ENST00000281092.4
ENST00000536402.1
 FER
 fer (fps/fes related) tyrosine kinase
chr5_+_82767487 0.24 ENST00000343200.5
ENST00000342785.4
 VCAN
 versican
chr8_+_77593448 0.23 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr4_+_155484155 0.23 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr3_-_114790179 0.23 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr4_+_88720698 0.22 ENST00000226284.5
 IBSP
 integrin-binding sialoprotein
chr2_+_17721230 0.21 ENST00000457525.1
 VSNL1
 visinin-like 1
chr5_+_82767583 0.21 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
 VCAN
 versican
chr12_-_8803128 0.21 ENST00000543467.1
 MFAP5
 microfibrillar associated protein 5
chr13_-_36429763 0.21 ENST00000379893.1
 DCLK1
 doublecortin-like kinase 1
chr4_+_80584903 0.20 ENST00000506460.1
 RP11-452C8.1
 RP11-452C8.1
chr16_-_20556492 0.20 ENST00000568098.1
 ACSM2B
 acyl-CoA synthetase medium-chain family member 2B
chr3_-_196911002 0.19 ENST00000452595.1
 DLG1
 discs, large homolog 1 (Drosophila)
chr14_+_39734482 0.18 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
 CTAGE5
 CTAGE family, member 5
chr11_-_128894053 0.18 ENST00000392657.3
 ARHGAP32
 Rho GTPase activating protein 32
chr17_+_61086917 0.18 ENST00000424789.2
ENST00000389520.4
 TANC2
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr15_+_65843130 0.18 ENST00000569894.1
 PTPLAD1
 protein tyrosine phosphatase-like A domain containing 1
chr8_-_49833978 0.17 ENST00000020945.1
 SNAI2
 snail family zinc finger 2
chr9_+_131447342 0.17 ENST00000409104.3
 SET
 SET nuclear oncogene
chr11_-_72432950 0.17 ENST00000426523.1
ENST00000429686.1
 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr8_-_141810634 0.17 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
 PTK2
 protein tyrosine kinase 2
chr7_+_2394445 0.16 ENST00000360876.4
ENST00000413917.1
ENST00000397011.2
 EIF3B
 eukaryotic translation initiation factor 3, subunit B
chr17_+_75315534 0.16 ENST00000590294.1
ENST00000329047.8
 SEPT9
 septin 9
chr8_+_77593474 0.16 ENST00000455469.2
ENST00000050961.6
 ZFHX4
 zinc finger homeobox 4
chr10_+_13203543 0.16 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
 MCM10
 minichromosome maintenance complex component 10
chr13_+_50656307 0.16 ENST00000378180.4
 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
chr8_-_49834299 0.16 ENST00000396822.1
 SNAI2
 snail family zinc finger 2
chr3_-_33686743 0.16 ENST00000333778.6
ENST00000539981.1
 CLASP2
 cytoplasmic linker associated protein 2
chr11_-_77850629 0.16 ENST00000376156.3
ENST00000525870.1
ENST00000530454.1
ENST00000525755.1
ENST00000527099.1
ENST00000525761.1
ENST00000299626.5
 ALG8
 ALG8, alpha-1,3-glucosyltransferase
chr1_-_153363452 0.16 ENST00000368732.1
ENST00000368733.3
 S100A8
 S100 calcium binding protein A8
chr11_+_9406169 0.15 ENST00000379719.3
ENST00000527431.1
 IPO7
 importin 7
chr13_+_50570019 0.15 ENST00000442421.1
 TRIM13
 tripartite motif containing 13
chr19_-_14889349 0.15 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
 EMR2
 egf-like module containing, mucin-like, hormone receptor-like 2
chr4_+_155484103 0.15 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr17_+_66521936 0.14 ENST00000592800.1
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chrX_-_70474910 0.14 ENST00000373988.1
ENST00000373998.1
 ZMYM3
 zinc finger, MYM-type 3
chr17_+_48823896 0.14 ENST00000511974.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr22_-_36220420 0.14 ENST00000473487.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr5_+_159848854 0.14 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
 PTTG1
 pituitary tumor-transforming 1
chr3_-_170744498 0.14 ENST00000382808.4
ENST00000314251.3
 SLC2A2
 solute carrier family 2 (facilitated glucose transporter), member 2
chrM_+_4431 0.13 ENST00000361453.3
 MT-ND2
 mitochondrially encoded NADH dehydrogenase 2
chr2_+_103035102 0.13 ENST00000264260.2
 IL18RAP
 interleukin 18 receptor accessory protein
chrX_-_32173579 0.13 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
 DMD
 dystrophin
chr5_+_148206156 0.13 ENST00000305988.4
 ADRB2
 adrenoceptor beta 2, surface
chr2_-_145275228 0.12 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr12_-_102591604 0.12 ENST00000329406.4
 PMCH
 pro-melanin-concentrating hormone
chr4_+_41937131 0.12 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
 TMEM33
 transmembrane protein 33
chr5_-_78281603 0.12 ENST00000264914.4
 ARSB
 arylsulfatase B
chr8_-_18666360 0.12 ENST00000286485.8
 PSD3
 pleckstrin and Sec7 domain containing 3
chr4_-_76957214 0.12 ENST00000306621.3
 CXCL11
 chemokine (C-X-C motif) ligand 11
chr4_-_10686475 0.11 ENST00000226951.6
 CLNK
 cytokine-dependent hematopoietic cell linker
chr12_-_10978957 0.11 ENST00000240619.2
 TAS2R10
 taste receptor, type 2, member 10
chr9_+_92219919 0.11 ENST00000252506.6
ENST00000375769.1
 GADD45G
 growth arrest and DNA-damage-inducible, gamma
chr4_+_95376396 0.11 ENST00000508216.1
ENST00000514743.1
 PDLIM5
 PDZ and LIM domain 5
chrX_+_123095546 0.11 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
 STAG2
 stromal antigen 2
chr8_-_141774467 0.11 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
 PTK2
 protein tyrosine kinase 2
chr1_-_244006528 0.11 ENST00000336199.5
ENST00000263826.5
 AKT3
 v-akt murine thymoma viral oncogene homolog 3
chr1_-_36615065 0.11 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
 TRAPPC3
 trafficking protein particle complex 3
chr6_+_32936353 0.11 ENST00000374825.4
 BRD2
 bromodomain containing 2
chr3_-_123339343 0.11 ENST00000578202.1
 MYLK
 myosin light chain kinase
chr8_-_102181718 0.10 ENST00000565617.1
 KB-1460A1.5
 KB-1460A1.5
chr20_-_13765526 0.10 ENST00000202816.1
 ESF1
 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr12_+_41831485 0.10 ENST00000539469.2
ENST00000298919.7
 PDZRN4
 PDZ domain containing ring finger 4
chr19_-_18433910 0.10 ENST00000594828.3
ENST00000593829.1
 LSM4
 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_+_73156664 0.10 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
 CDH23
 cadherin-related 23
chr3_-_123339418 0.10 ENST00000583087.1
 MYLK
 myosin light chain kinase
chrX_+_47092314 0.10 ENST00000218348.3
 USP11
 ubiquitin specific peptidase 11
chr1_+_117963209 0.10 ENST00000449370.2
 MAN1A2
 mannosidase, alpha, class 1A, member 2
chr16_+_10837643 0.10 ENST00000574334.1
ENST00000283027.5
ENST00000433392.2
 NUBP1
 nucleotide binding protein 1
chr1_-_36615051 0.10 ENST00000373163.1
 TRAPPC3
 trafficking protein particle complex 3
chr5_-_179047881 0.10 ENST00000521173.1
 HNRNPH1
 heterogeneous nuclear ribonucleoprotein H1 (H)
chr11_-_72433346 0.10 ENST00000334211.8
 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr2_+_120436733 0.09 ENST00000401466.1
ENST00000424086.1
ENST00000272521.6
 TMEM177
 transmembrane protein 177
chr2_-_24270217 0.09 ENST00000295148.4
ENST00000406895.3
 C2orf44
 chromosome 2 open reading frame 44
chr5_+_167718604 0.09 ENST00000265293.4
 WWC1
 WW and C2 domain containing 1
chr8_-_121457332 0.09 ENST00000518918.1
 MRPL13
 mitochondrial ribosomal protein L13
chrM_+_12331 0.09 ENST00000361567.2
 MT-ND5
 mitochondrially encoded NADH dehydrogenase 5
chr15_-_56757329 0.09 ENST00000260453.3
 MNS1
 meiosis-specific nuclear structural 1
chr22_-_42086477 0.09 ENST00000402458.1
 NHP2L1
 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr5_+_159848807 0.09 ENST00000352433.5
 PTTG1
 pituitary tumor-transforming 1
chr8_+_110552337 0.09 ENST00000337573.5
 EBAG9
 estrogen receptor binding site associated, antigen, 9
chr5_+_125758865 0.09 ENST00000542322.1
ENST00000544396.1
 GRAMD3
 GRAM domain containing 3
chr12_-_71551652 0.09 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr1_+_202431859 0.08 ENST00000391959.3
ENST00000367270.4
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr21_-_36421401 0.08 ENST00000486278.2
 RUNX1
 runt-related transcription factor 1
chr2_-_27558270 0.08 ENST00000454704.1
 GTF3C2
 general transcription factor IIIC, polypeptide 2, beta 110kDa
chr7_+_102715315 0.08 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
 ARMC10
 armadillo repeat containing 10
chr5_-_11588907 0.08 ENST00000513598.1
ENST00000503622.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr5_-_58335281 0.08 ENST00000358923.6
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr12_+_14572070 0.08 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
 ATF7IP
 activating transcription factor 7 interacting protein
chr1_+_15272271 0.08 ENST00000400797.3
 KAZN
 kazrin, periplakin interacting protein
chr15_-_42840961 0.08 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
 LRRC57
 leucine rich repeat containing 57
chr6_-_11779014 0.07 ENST00000229583.5
 ADTRP
 androgen-dependent TFPI-regulating protein
chr5_+_125758813 0.07 ENST00000285689.3
ENST00000515200.1
 GRAMD3
 GRAM domain containing 3
chr17_-_2966901 0.07 ENST00000575751.1
 OR1D5
 olfactory receptor, family 1, subfamily D, member 5
chr7_-_22233442 0.07 ENST00000401957.2
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr4_-_110723335 0.07 ENST00000394634.2
 CFI
 complement factor I
chr6_-_150067632 0.07 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
 NUP43
 nucleoporin 43kDa
chr18_-_60985914 0.07 ENST00000589955.1
 BCL2
 B-cell CLL/lymphoma 2
chr20_+_30697510 0.07 ENST00000217315.5
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr14_-_50154921 0.07 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
 POLE2
 polymerase (DNA directed), epsilon 2, accessory subunit
chr17_+_48823975 0.07 ENST00000513969.1
ENST00000503728.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr6_+_44355257 0.06 ENST00000371477.3
 CDC5L
 cell division cycle 5-like
chr16_+_22501658 0.06 ENST00000415833.2
 NPIPB5
 nuclear pore complex interacting protein family, member B5
chr11_-_11374904 0.06 ENST00000528848.2
 CSNK2A3
 casein kinase 2, alpha 3 polypeptide
chr17_+_7591639 0.06 ENST00000396463.2
 WRAP53
 WD repeat containing, antisense to TP53
chr6_-_150067696 0.06 ENST00000340413.2
ENST00000367403.3
 NUP43
 nucleoporin 43kDa
chr20_+_30697298 0.06 ENST00000398022.2
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr2_+_162087577 0.06 ENST00000439442.1
 TANK
 TRAF family member-associated NFKB activator
chr1_+_150898812 0.06 ENST00000271640.5
ENST00000448029.1
ENST00000368962.2
ENST00000534805.1
ENST00000368969.4
ENST00000368963.1
ENST00000498193.1
 SETDB1
 SET domain, bifurcated 1
chr8_-_133637624 0.06 ENST00000522789.1
 LRRC6
 leucine rich repeat containing 6
chr19_+_47634039 0.06 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
 SAE1
 SUMO1 activating enzyme subunit 1
chr6_+_45296391 0.06 ENST00000371436.6
ENST00000576263.1
 RUNX2
 runt-related transcription factor 2
chr8_-_22526597 0.06 ENST00000519513.1
ENST00000276416.6
ENST00000520292.1
ENST00000522268.1
 BIN3
 bridging integrator 3
chr1_-_31538517 0.06 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
 PUM1
 pumilio RNA-binding family member 1
chr14_+_39703084 0.06 ENST00000553728.1
 RP11-407N17.3
 cTAGE family member 5 isoform 4
chr7_-_107443652 0.06 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
 SLC26A3
 solute carrier family 26 (anion exchanger), member 3
chr19_-_39881669 0.06 ENST00000221266.7
 PAF1
 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr5_+_40909354 0.05 ENST00000313164.9
 C7
 complement component 7
chr13_+_25875785 0.05 ENST00000381747.3
 NUPL1
 nucleoporin like 1
chr18_-_60986613 0.05 ENST00000444484.1
 BCL2
 B-cell CLL/lymphoma 2
chr9_+_123970052 0.05 ENST00000373823.3
 GSN
 gelsolin
chr12_+_52056548 0.05 ENST00000545061.1
ENST00000355133.3
 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
chr2_+_162272605 0.05 ENST00000389554.3
 TBR1
 T-box, brain, 1
chr13_+_25875662 0.05 ENST00000381736.3
ENST00000463407.1
ENST00000381718.3
 NUPL1
 nucleoporin like 1
chr5_-_58652788 0.05 ENST00000405755.2
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr13_+_102104952 0.05 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr20_+_56964169 0.05 ENST00000475243.1
 VAPB
 VAMP (vesicle-associated membrane protein)-associated protein B and C
chr7_-_22234381 0.05 ENST00000458533.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr8_+_110552831 0.05 ENST00000530629.1
 EBAG9
 estrogen receptor binding site associated, antigen, 9
chr14_-_25078864 0.05 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
 GZMH
 granzyme H (cathepsin G-like 2, protein h-CCPX)
chr2_+_171034646 0.05 ENST00000409044.3
ENST00000408978.4
 MYO3B
 myosin IIIB
chr2_+_152266392 0.05 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
 RIF1
 RAP1 interacting factor homolog (yeast)
chr2_-_217724767 0.05 ENST00000236979.2
 TNP1
 transition protein 1 (during histone to protamine replacement)
chr1_+_224301787 0.05 ENST00000366862.5
ENST00000424254.2
 FBXO28
 F-box protein 28
chr6_+_20534672 0.05 ENST00000274695.4
ENST00000378624.4
 CDKAL1
 CDK5 regulatory subunit associated protein 1-like 1
chr17_+_38171681 0.05 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
 CSF3
 colony stimulating factor 3 (granulocyte)
chr17_-_42143963 0.04 ENST00000585388.1
ENST00000293406.3
 LSM12
 LSM12 homolog (S. cerevisiae)
chr1_+_171217622 0.04 ENST00000433267.1
ENST00000367750.3
 FMO1
 flavin containing monooxygenase 1
chr7_+_32535060 0.04 ENST00000318709.4
ENST00000409301.1
ENST00000404479.1
 AVL9
 AVL9 homolog (S. cerevisiase)
chr1_-_160231451 0.04 ENST00000495887.1
 DCAF8
 DDB1 and CUL4 associated factor 8
chr18_+_9103957 0.04 ENST00000400033.1
 NDUFV2
 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr1_+_211433275 0.04 ENST00000367005.4
 RCOR3
 REST corepressor 3
chr17_+_7591747 0.04 ENST00000534050.1
 WRAP53
 WD repeat containing, antisense to TP53
chr4_+_113739244 0.04 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
 ANK2
 ankyrin 2, neuronal
chr9_-_86593238 0.04 ENST00000351839.3
 HNRNPK
 heterogeneous nuclear ribonucleoprotein K
chrX_-_70473957 0.04 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
 ZMYM3
 zinc finger, MYM-type 3
chr7_+_93535866 0.04 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
 GNGT1
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr8_-_122653630 0.04 ENST00000303924.4
 HAS2
 hyaluronan synthase 2
chr17_+_38171614 0.04 ENST00000583218.1
ENST00000394149.3
 CSF3
 colony stimulating factor 3 (granulocyte)
chr8_-_121457608 0.04 ENST00000306185.3
 MRPL13
 mitochondrial ribosomal protein L13
chr5_-_11589131 0.04 ENST00000511377.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr5_-_98262240 0.04 ENST00000284049.3
 CHD1
 chromodomain helicase DNA binding protein 1
chr9_+_71944241 0.04 ENST00000257515.8
 FAM189A2
 family with sequence similarity 189, member A2
chr2_-_40739501 0.04 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_+_144303093 0.04 ENST00000505913.1
 GAB1
 GRB2-associated binding protein 1
chr6_+_45296048 0.04 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
 RUNX2
 runt-related transcription factor 2
chr9_+_37753795 0.04 ENST00000377753.2
ENST00000537911.1
ENST00000377754.2
ENST00000297994.3
 TRMT10B
 tRNA methyltransferase 10 homolog B (S. cerevisiae)
chrX_-_153363188 0.03 ENST00000303391.6
 MECP2
 methyl CpG binding protein 2 (Rett syndrome)
chr3_-_113897899 0.03 ENST00000383673.2
ENST00000295881.7
 DRD3
 dopamine receptor D3
chr5_+_140552218 0.03 ENST00000231137.3
 PCDHB7
 protocadherin beta 7
chr4_+_95679072 0.03 ENST00000515059.1
 BMPR1B
 bone morphogenetic protein receptor, type IB
chr6_+_55039050 0.03 ENST00000370862.3
 HCRTR2
 hypocretin (orexin) receptor 2
chr7_+_93535817 0.03 ENST00000248572.5
 GNGT1
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_120315074 0.03 ENST00000261833.7
ENST00000392521.2
 CIT
 citron (rho-interacting, serine/threonine kinase 21)
chrX_-_130037198 0.03 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
 ENOX2
 ecto-NOX disulfide-thiol exchanger 2
chr8_-_134072593 0.03 ENST00000427060.2
 SLA
 Src-like-adaptor
chr1_+_50459990 0.03 ENST00000448346.1
 AL645730.2
 AL645730.2
chr1_-_110155671 0.03 ENST00000351050.3
 GNAT2
 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr5_+_34757309 0.03 ENST00000397449.1
 RAI14
 retinoic acid induced 14
chr3_+_189507523 0.03 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
 TP63
 tumor protein p63
chr1_-_115259337 0.03 ENST00000369535.4
 NRAS
 neuroblastoma RAS viral (v-ras) oncogene homolog
chr5_+_140602904 0.03 ENST00000515856.2
ENST00000239449.4
 PCDHB14
 protocadherin beta 14
chr9_-_95166841 0.03 ENST00000262551.4
 OGN
 osteoglycin

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 1.6 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.0 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.2 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.3 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.3 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.6 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)