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ENCODE cell lines, expression (Ernst 2011)

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Results for NKX2-6

Z-value: 1.18

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Transcription factors associated with NKX2-6

Gene Symbol Gene ID Gene Info
ENSG00000180053.6 NKX2-6

Activity profile of NKX2-6 motif

Sorted Z-values of NKX2-6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_121379739 5.43 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_-_15103621 3.35 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr15_-_55563072 2.27 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr6_+_33043703 2.16 ENST00000418931.2
ENST00000535465.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr11_-_76381029 2.05 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr7_+_142498725 1.99 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr22_-_37882395 1.91 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr10_-_6019552 1.63 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr10_-_6019984 1.56 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr1_+_158900568 1.50 ENST00000458222.1
PYHIN1
pyrin and HIN domain family, member 1
chr22_+_23229960 1.46 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr1_+_158969752 1.32 ENST00000566111.1
IFI16
interferon, gamma-inducible protein 16
chr2_+_102928009 1.31 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr19_+_52076425 1.15 ENST00000436511.2
ZNF175
zinc finger protein 175
chr8_-_120651020 1.12 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr19_+_52074502 1.08 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175
zinc finger protein 175
chr9_+_116263639 0.90 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr17_+_33914460 0.88 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr6_-_26216872 0.88 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr17_+_33914276 0.85 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr3_-_127541194 0.84 ENST00000453507.2
MGLL
monoglyceride lipase
chr2_-_175462934 0.83 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr9_+_125133315 0.83 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr15_+_81475047 0.82 ENST00000559388.1
IL16
interleukin 16
chr22_-_24096562 0.81 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr11_+_94277017 0.81 ENST00000358752.2
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chrX_-_47518527 0.80 ENST00000333119.3
UXT
ubiquitously-expressed, prefoldin-like chaperone
chr4_-_156875003 0.74 ENST00000433477.3
CTSO
cathepsin O
chr9_+_125132803 0.71 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_+_41386761 0.67 ENST00000523277.2
GINS4
GINS complex subunit 4 (Sld5 homolog)
chrX_-_47518498 0.66 ENST00000335890.2
UXT
ubiquitously-expressed, prefoldin-like chaperone
chr9_+_134065506 0.66 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr5_-_111091948 0.65 ENST00000447165.2
NREP
neuronal regeneration related protein
chr4_+_17579110 0.62 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chr20_-_36793663 0.61 ENST00000536701.1
ENST00000536724.1
TGM2
transglutaminase 2
chr13_+_115000521 0.61 ENST00000252457.5
ENST00000375308.1
CDC16
cell division cycle 16
chr5_-_133510456 0.60 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr17_-_41116454 0.59 ENST00000427569.2
ENST00000430739.1
AARSD1
alanyl-tRNA synthetase domain containing 1
chr5_-_169725231 0.58 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_+_132316081 0.58 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr1_+_16767167 0.57 ENST00000337132.5
NECAP2
NECAP endocytosis associated 2
chr17_-_26903900 0.56 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr17_-_47723943 0.55 ENST00000510476.1
ENST00000503676.1
SPOP
speckle-type POZ protein
chrX_+_30261847 0.55 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr3_+_37035289 0.55 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1
mutL homolog 1
chr2_-_175462456 0.54 ENST00000409891.1
ENST00000410117.1
WIPF1
WAS/WASL interacting protein family, member 1
chr1_+_173793641 0.53 ENST00000361951.4
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr22_-_24096630 0.53 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr12_-_44152551 0.52 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr20_-_1373606 0.51 ENST00000381715.1
ENST00000439640.2
ENST00000381719.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr10_+_121652204 0.50 ENST00000369075.3
ENST00000543134.1
SEC23IP
SEC23 interacting protein
chr4_-_73434498 0.50 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr12_+_118454500 0.49 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
RFC5
replication factor C (activator 1) 5, 36.5kDa
chr11_+_65627865 0.47 ENST00000308110.4
MUS81
MUS81 structure-specific endonuclease subunit
chr13_+_115000556 0.44 ENST00000252458.6
CDC16
cell division cycle 16
chr8_+_20054878 0.44 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr1_+_16767195 0.43 ENST00000504551.2
ENST00000457722.2
ENST00000406746.1
ENST00000443980.2
NECAP2
NECAP endocytosis associated 2
chr6_+_24775641 0.43 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr7_+_100466433 0.41 ENST00000429658.1
TRIP6
thyroid hormone receptor interactor 6
chr3_-_81811312 0.41 ENST00000429644.2
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr7_-_112430647 0.40 ENST00000312814.6
TMEM168
transmembrane protein 168
chr12_+_60083118 0.40 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_-_27545921 0.40 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MPV17
MpV17 mitochondrial inner membrane protein
chr1_+_173793777 0.40 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr3_+_121796697 0.39 ENST00000482356.1
ENST00000393627.2
CD86
CD86 molecule
chr2_+_86426478 0.39 ENST00000254644.8
ENST00000605125.1
ENST00000337109.4
ENST00000409180.1
MRPL35
mitochondrial ribosomal protein L35
chr8_-_95220775 0.38 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr14_+_100531615 0.38 ENST00000392920.3
EVL
Enah/Vasp-like
chr5_-_176889381 0.37 ENST00000393563.4
ENST00000512501.1
DBN1
drebrin 1
chr11_-_6640585 0.33 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
TPP1
tripeptidyl peptidase I
chr3_+_37034823 0.33 ENST00000231790.2
ENST00000456676.2
MLH1
mutL homolog 1
chr10_+_18629628 0.32 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr1_+_158259558 0.32 ENST00000368170.3
CD1C
CD1c molecule
chr15_-_20170354 0.31 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr17_-_62493131 0.31 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr17_+_60501228 0.31 ENST00000311506.5
METTL2A
methyltransferase like 2A
chr3_-_46249878 0.31 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chr10_+_135204338 0.30 ENST00000468317.2
RP11-108K14.8
Mitochondrial GTPase 1
chr15_-_72668805 0.29 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr9_+_131452239 0.29 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr14_-_60337684 0.29 ENST00000267484.5
RTN1
reticulon 1
chr3_-_114790179 0.29 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_66360665 0.29 ENST00000310190.4
CCS
copper chaperone for superoxide dismutase
chr19_+_3178736 0.29 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr5_+_140071178 0.28 ENST00000508522.1
ENST00000448069.2
HARS2
histidyl-tRNA synthetase 2, mitochondrial
chr7_+_110731062 0.28 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr7_-_6865826 0.28 ENST00000538180.1
CCZ1B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
chr9_+_131447342 0.28 ENST00000409104.3
SET
SET nuclear oncogene
chr10_+_115939008 0.27 ENST00000369282.1
ENST00000251864.2
ENST00000369281.2
ENST00000422662.1
TDRD1
tudor domain containing 1
chr19_+_7701985 0.26 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
STXBP2
syntaxin binding protein 2
chr2_-_100721178 0.25 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr2_-_25565377 0.25 ENST00000264709.3
ENST00000406659.3
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_+_25621102 0.24 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1
WD repeat and SOCS box containing 1
chr19_+_17186577 0.24 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr1_+_110163202 0.23 ENST00000531203.1
ENST00000256578.3
AMPD2
adenosine monophosphate deaminase 2
chr7_+_5938386 0.23 ENST00000537980.1
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr12_-_71182695 0.22 ENST00000342084.4
PTPRR
protein tyrosine phosphatase, receptor type, R
chr8_-_121457608 0.22 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr14_-_106805716 0.21 ENST00000438142.2
IGHV4-31
immunoglobulin heavy variable 4-31
chr11_+_98891797 0.21 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
CNTN5
contactin 5
chr20_-_5100591 0.21 ENST00000379143.5
PCNA
proliferating cell nuclear antigen
chr10_-_6019455 0.21 ENST00000530685.1
ENST00000397255.3
ENST00000379971.1
ENST00000528354.1
ENST00000397250.2
ENST00000429135.2
IL15RA
interleukin 15 receptor, alpha
chr16_+_69796209 0.20 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr6_-_144416737 0.20 ENST00000367569.2
SF3B5
splicing factor 3b, subunit 5, 10kDa
chr12_+_44152740 0.20 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr7_+_5938351 0.20 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr4_+_88532028 0.19 ENST00000282478.7
DSPP
dentin sialophosphoprotein
chr12_-_57039739 0.19 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr11_-_118901559 0.19 ENST00000330775.7
ENST00000545985.1
ENST00000357590.5
ENST00000538950.1
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_-_115259337 0.17 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr7_+_101917407 0.17 ENST00000487284.1
CUX1
cut-like homeobox 1
chr1_-_21113105 0.16 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
HP1BP3
heterochromatin protein 1, binding protein 3
chr5_+_140071011 0.16 ENST00000230771.3
ENST00000509299.1
ENST00000503873.1
ENST00000435019.2
ENST00000437649.2
ENST00000432671.2
HARS2
histidyl-tRNA synthetase 2, mitochondrial
chr17_-_7216939 0.15 ENST00000573684.1
GPS2
G protein pathway suppressor 2
chr11_+_118958689 0.15 ENST00000535253.1
ENST00000392841.1
HMBS
hydroxymethylbilane synthase
chr17_+_61562201 0.15 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
ACE
angiotensin I converting enzyme
chr14_+_64680854 0.15 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr7_-_56101826 0.14 ENST00000421626.1
PSPH
phosphoserine phosphatase
chrX_-_47341928 0.14 ENST00000313116.7
ZNF41
zinc finger protein 41
chr12_-_56236690 0.14 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr8_+_50824233 0.14 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr19_+_42746927 0.14 ENST00000378108.1
AC006486.1
AC006486.1
chr12_+_113354341 0.14 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_171217677 0.13 ENST00000402921.2
FMO1
flavin containing monooxygenase 1
chr14_+_50779071 0.12 ENST00000426751.2
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr15_-_56757329 0.12 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr8_-_121457332 0.12 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr15_-_65579177 0.12 ENST00000444347.2
ENST00000261888.6
PARP16
poly (ADP-ribose) polymerase family, member 16
chr15_-_28344439 0.12 ENST00000431101.1
ENST00000445578.1
ENST00000353809.5
ENST00000382996.2
ENST00000354638.3
OCA2
oculocutaneous albinism II
chr1_-_48866517 0.12 ENST00000371841.1
SPATA6
spermatogenesis associated 6
chr19_-_49527590 0.11 ENST00000357383.4
CGB
chorionic gonadotropin, beta polypeptide
chr1_+_144989309 0.11 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr9_-_215744 0.11 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr6_-_32977345 0.11 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr4_-_79860506 0.11 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr19_-_44174330 0.11 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr12_-_371994 0.11 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr19_-_44174305 0.11 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr1_-_31902614 0.11 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr16_-_69373396 0.11 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr17_-_34890709 0.10 ENST00000544606.1
MYO19
myosin XIX
chr14_+_31494672 0.10 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr19_-_49552006 0.09 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr20_-_36661826 0.09 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr14_+_50779029 0.09 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr13_-_44453826 0.09 ENST00000444614.3
CCDC122
coiled-coil domain containing 122
chr1_-_169337176 0.09 ENST00000472647.1
ENST00000367811.3
NME7
NME/NM23 family member 7
chr7_-_150777874 0.09 ENST00000540185.1
FASTK
Fas-activated serine/threonine kinase
chr11_-_111383064 0.08 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
BTG4
B-cell translocation gene 4
chr17_-_34890732 0.08 ENST00000268852.9
MYO19
myosin XIX
chr11_-_66360548 0.08 ENST00000333861.3
CCDC87
coiled-coil domain containing 87
chr9_-_70465758 0.08 ENST00000489273.1
CBWD5
COBW domain containing 5
chr7_+_128116783 0.07 ENST00000262432.8
ENST00000480046.1
METTL2B
methyltransferase like 2B
chr22_+_42017987 0.07 ENST00000405506.1
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr15_+_43425672 0.06 ENST00000260403.2
TMEM62
transmembrane protein 62
chr4_+_70916119 0.06 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr5_+_34757309 0.06 ENST00000397449.1
RAI14
retinoic acid induced 14
chr2_-_87088995 0.06 ENST00000393759.2
ENST00000349455.3
ENST00000331469.2
ENST00000431506.2
ENST00000393761.2
ENST00000390655.6
CD8B
CD8b molecule
chr8_-_30706608 0.06 ENST00000256246.2
TEX15
testis expressed 15
chr17_-_56606639 0.06 ENST00000579371.1
SEPT4
septin 4
chr17_+_41150793 0.06 ENST00000586277.1
RPL27
ribosomal protein L27
chr17_-_56606705 0.06 ENST00000317268.3
SEPT4
septin 4
chr11_-_64527425 0.05 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr13_+_27998681 0.05 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr1_+_205225319 0.05 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr14_+_21236586 0.05 ENST00000326783.3
EDDM3B
epididymal protein 3B
chr5_+_52083730 0.05 ENST00000282588.6
ENST00000274311.2
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr15_-_41120896 0.05 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr17_-_56606664 0.04 ENST00000580844.1
SEPT4
septin 4
chr20_-_1373682 0.04 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr16_-_20367584 0.04 ENST00000570689.1
UMOD
uromodulin
chr6_+_42584847 0.04 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_+_110162448 0.03 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2
adenosine monophosphate deaminase 2
chr1_+_233086326 0.03 ENST00000366628.5
ENST00000366627.4
NTPCR
nucleoside-triphosphatase, cancer-related
chr5_+_140723601 0.03 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chrX_+_151081351 0.03 ENST00000276344.2
MAGEA4
melanoma antigen family A, 4
chr11_-_61687739 0.03 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr19_+_58144529 0.03 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr17_+_41150479 0.03 ENST00000589913.1
RPL27
ribosomal protein L27
chr1_-_175712665 0.03 ENST00000263525.2
TNR
tenascin R
chr9_-_33402506 0.03 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr21_-_31311818 0.02 ENST00000535441.1
ENST00000309434.7
ENST00000327783.4
ENST00000389124.2
ENST00000389125.3
ENST00000399913.1
GRIK1
glutamate receptor, ionotropic, kainate 1
chr1_+_113009163 0.02 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr2_-_187367356 0.02 ENST00000595956.1
AC018867.2
AC018867.2
chr2_+_219246746 0.02 ENST00000233202.6
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr14_+_31494841 0.02 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr11_-_129817448 0.02 ENST00000304538.6
PRDM10
PR domain containing 10
chr3_-_113956425 0.02 ENST00000482457.2
ZNF80
zinc finger protein 80
chr2_+_102927962 0.01 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr12_-_50290839 0.01 ENST00000552863.1
FAIM2
Fas apoptotic inhibitory molecule 2
chr13_-_48669232 0.01 ENST00000258648.2
ENST00000378586.1
MED4
mediator complex subunit 4
chr17_-_44896047 0.00 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr17_-_34890665 0.00 ENST00000586007.1
MYO19
myosin XIX
chr7_-_150777949 0.00 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr2_+_109335929 0.00 ENST00000283195.6
RANBP2
RAN binding protein 2

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005715 late recombination nodule(GO:0005715)
0.2 0.7 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 2.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.7 GO:0000811 GINS complex(GO:0000811)
0.1 0.6 GO:0036398 TCR signalosome(GO:0036398)
0.1 2.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.7 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 3.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 1.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.3 GO:0071546 pi-body(GO:0071546)
0.1 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 5.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 3.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0071461 cellular response to redox state(GO:0071461)
0.4 2.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.3 1.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 5.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 0.9 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 0.9 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.2 1.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 0.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 2.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.4 GO:0042109 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.4 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 1.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.8 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.5 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 3.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.2 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.4 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.8 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 2.0 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 1.3 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 1.3 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 1.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 3.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 1.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 0.6 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.9 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.4 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 2.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.9 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.2 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.8 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.5 GO:0048256 flap endonuclease activity(GO:0048256)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 3.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 2.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 6.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 4.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.0 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 3.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)