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ENCODE cell lines, expression (Ernst 2011)

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Results for NKX2-8

Z-value: 0.98

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
NKX2-8
ENSG00000136327.6 NKX2-8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg19_v2_chr14_-_37051798_37051831-0.273.2e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_106692191 3.74 ENST00000390607.2
 IGHV3-21
 immunoglobulin heavy variable 3-21
chr14_-_106573756 3.44 ENST00000390601.2
 IGHV3-11
 immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr12_+_25205568 2.86 ENST00000548766.1
ENST00000556887.1
 LRMP
 lymphoid-restricted membrane protein
chr14_-_106994333 2.75 ENST00000390624.2
 IGHV3-48
 immunoglobulin heavy variable 3-48
chr16_+_32077386 2.59 ENST00000354689.6
 IGHV3OR16-9
 immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr13_-_46756351 2.48 ENST00000323076.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_106518922 2.30 ENST00000390598.2
 IGHV3-7
 immunoglobulin heavy variable 3-7
chr13_-_46964177 2.26 ENST00000389908.3
 KIAA0226L
 KIAA0226-like
chr14_-_106552755 2.25 ENST00000390600.2
 IGHV3-9
 immunoglobulin heavy variable 3-9
chr12_+_25205666 2.24 ENST00000547044.1
 LRMP
 lymphoid-restricted membrane protein
chr14_-_107049312 2.21 ENST00000390627.2
 IGHV3-53
 immunoglobulin heavy variable 3-53
chr14_-_107219365 2.12 ENST00000424969.2
 IGHV3-74
 immunoglobulin heavy variable 3-74
chr14_-_106963409 2.07 ENST00000390621.2
 IGHV1-45
 immunoglobulin heavy variable 1-45
chr6_-_137113604 1.69 ENST00000359015.4
 MAP3K5
 mitogen-activated protein kinase kinase kinase 5
chr7_+_99816859 1.68 ENST00000317271.2
 PVRIG
 poliovirus receptor related immunoglobulin domain containing
chr3_-_16524357 1.59 ENST00000432519.1
 RFTN1
 raftlin, lipid raft linker 1
chr14_-_107131560 1.44 ENST00000390632.2
 IGHV3-66
 immunoglobulin heavy variable 3-66
chr12_-_12837423 1.38 ENST00000540510.1
 GPR19
 G protein-coupled receptor 19
chr12_+_25205446 1.37 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
 LRMP
 lymphoid-restricted membrane protein
chr6_-_133084580 1.36 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
 VNN2
 vanin 2
chr14_-_106845789 1.31 ENST00000390617.2
 IGHV3-35
 immunoglobulin heavy variable 3-35 (non-functional)
chr6_-_32731299 1.27 ENST00000435145.2
ENST00000437316.2
 HLA-DQB2
 major histocompatibility complex, class II, DQ beta 2
chr16_-_33647696 1.26 ENST00000558425.1
ENST00000569103.2
 RP11-812E19.9
 Uncharacterized protein
chr8_-_81083341 1.20 ENST00000519303.2
 TPD52
 tumor protein D52
chr16_+_88872176 1.18 ENST00000569140.1
 CDT1
 chromatin licensing and DNA replication factor 1
chr16_+_33020496 0.95 ENST00000565407.2
 IGHV3OR16-8
 immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr8_+_27182862 0.88 ENST00000521164.1
ENST00000346049.5
 PTK2B
 protein tyrosine kinase 2 beta
chr15_-_20170354 0.84 ENST00000338912.5
 IGHV1OR15-9
 immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr12_-_21810765 0.77 ENST00000450584.1
ENST00000350669.1
 LDHB
 lactate dehydrogenase B
chr19_+_34856141 0.76 ENST00000586425.1
 GPI
 glucose-6-phosphate isomerase
chr5_-_95158644 0.75 ENST00000237858.6
 GLRX
 glutaredoxin (thioltransferase)
chr12_-_21810726 0.75 ENST00000396076.1
 LDHB
 lactate dehydrogenase B
chr5_+_68665608 0.70 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
 RAD17
 RAD17 homolog (S. pombe)
chr3_-_8811288 0.66 ENST00000316793.3
ENST00000431493.1
 OXTR
 oxytocin receptor
chr3_+_4535025 0.66 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
 ITPR1
 inositol 1,4,5-trisphosphate receptor, type 1
chr16_+_32063311 0.66 ENST00000426099.1
 AC142381.1
 AC142381.1
chr7_-_5998714 0.64 ENST00000539903.1
 RSPH10B
 radial spoke head 10 homolog B (Chlamydomonas)
chrX_-_48776292 0.62 ENST00000376509.4
 PIM2
 pim-2 oncogene
chr6_-_32731243 0.62 ENST00000427449.1
ENST00000411527.1
 HLA-DQB2
 major histocompatibility complex, class II, DQ beta 2
chr17_+_76210367 0.61 ENST00000592734.1
ENST00000587746.1
 BIRC5
 baculoviral IAP repeat containing 5
chr12_-_102591604 0.58 ENST00000329406.4
 PMCH
 pro-melanin-concentrating hormone
chr15_-_75248954 0.55 ENST00000499788.2
 RPP25
 ribonuclease P/MRP 25kDa subunit
chr17_+_46184911 0.54 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
 SNX11
 sorting nexin 11
chr7_-_137686791 0.54 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
 CREB3L2
 cAMP responsive element binding protein 3-like 2
chrX_-_69479654 0.52 ENST00000374519.2
 P2RY4
 pyrimidinergic receptor P2Y, G-protein coupled, 4
chr12_+_51442101 0.50 ENST00000550929.1
ENST00000262055.4
ENST00000550442.1
ENST00000549340.1
ENST00000548209.1
ENST00000548251.1
ENST00000550814.1
ENST00000547660.1
ENST00000380123.2
ENST00000548401.1
ENST00000418425.2
ENST00000547008.1
ENST00000552739.1
 LETMD1
 LETM1 domain containing 1
chr16_-_3767506 0.46 ENST00000538171.1
 TRAP1
 TNF receptor-associated protein 1
chr3_+_63953415 0.45 ENST00000484332.1
 ATXN7
 ataxin 7
chrX_-_32173579 0.44 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
 DMD
 dystrophin
chr12_+_121837905 0.41 ENST00000392465.3
ENST00000554606.1
ENST00000392464.2
ENST00000555076.1
 RNF34
 ring finger protein 34, E3 ubiquitin protein ligase
chr16_+_33629600 0.40 ENST00000562905.2
 IGHV3OR16-13
 immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr11_-_133826852 0.40 ENST00000533871.2
ENST00000321016.8
 IGSF9B
 immunoglobulin superfamily, member 9B
chr16_+_33006369 0.40 ENST00000425181.3
 IGHV3OR16-10
 immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr14_-_106586656 0.39 ENST00000390602.2
 IGHV3-13
 immunoglobulin heavy variable 3-13
chr13_-_23949671 0.39 ENST00000402364.1
 SACS
 spastic ataxia of Charlevoix-Saguenay (sacsin)
chr15_-_70387120 0.38 ENST00000539550.1
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr16_-_3767551 0.36 ENST00000246957.5
 TRAP1
 TNF receptor-associated protein 1
chr3_-_125094093 0.35 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
 ZNF148
 zinc finger protein 148
chr10_-_15762124 0.35 ENST00000378076.3
 ITGA8
 integrin, alpha 8
chr19_-_39322497 0.35 ENST00000221418.4
 ECH1
 enoyl CoA hydratase 1, peroxisomal
chr10_+_71078595 0.34 ENST00000359426.6
 HK1
 hexokinase 1
chrX_-_110655306 0.33 ENST00000371993.2
 DCX
 doublecortin
chr11_+_35211429 0.33 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
 CD44
 CD44 molecule (Indian blood group)
chrX_-_53461288 0.31 ENST00000375298.4
ENST00000375304.5
 HSD17B10
 hydroxysteroid (17-beta) dehydrogenase 10
chr15_-_28419569 0.31 ENST00000569772.1
 HERC2
 HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr1_+_74701062 0.31 ENST00000326637.3
 TNNI3K
 TNNI3 interacting kinase
chr5_+_43602750 0.30 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
 NNT
 nicotinamide nucleotide transhydrogenase
chr15_+_40453204 0.30 ENST00000287598.6
ENST00000412359.3
 BUB1B
 BUB1 mitotic checkpoint serine/threonine kinase B
chr19_+_36486078 0.30 ENST00000378887.2
 SDHAF1
 succinate dehydrogenase complex assembly factor 1
chr14_-_106622419 0.29 ENST00000390604.2
 IGHV3-16
 immunoglobulin heavy variable 3-16 (non-functional)
chr14_+_76618242 0.29 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
 GPATCH2L
 G patch domain containing 2-like
chr17_-_9808887 0.29 ENST00000226193.5
 RCVRN
 recoverin
chr14_-_58894332 0.28 ENST00000395159.2
 TIMM9
 translocase of inner mitochondrial membrane 9 homolog (yeast)
chr18_-_44497308 0.28 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
 PIAS2
 protein inhibitor of activated STAT, 2
chr19_+_52074502 0.27 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
 ZNF175
 zinc finger protein 175
chr7_-_86974767 0.27 ENST00000610086.1
 TP53TG1
 TP53 target 1 (non-protein coding)
chr2_+_207024306 0.26 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
 EEF1B2
 eukaryotic translation elongation factor 1 beta 2
chr10_+_118305435 0.25 ENST00000369221.2
 PNLIP
 pancreatic lipase
chr17_+_8191815 0.24 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
 RANGRF
 RAN guanine nucleotide release factor
chr8_+_128426535 0.24 ENST00000465342.2
 POU5F1B
 POU class 5 homeobox 1B
chr9_-_128412696 0.24 ENST00000420643.1
 MAPKAP1
 mitogen-activated protein kinase associated protein 1
chr11_-_19223523 0.24 ENST00000265968.3
 CSRP3
 cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr1_+_55464600 0.24 ENST00000371265.4
 BSND
 Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr12_+_66218212 0.23 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
 HMGA2
 high mobility group AT-hook 2
chr17_+_7591639 0.22 ENST00000396463.2
 WRAP53
 WD repeat containing, antisense to TP53
chr19_-_39322299 0.22 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
 ECH1
 enoyl CoA hydratase 1, peroxisomal
chr7_+_135242652 0.21 ENST00000285968.6
ENST00000440390.2
 NUP205
 nucleoporin 205kDa
chr20_-_48530230 0.21 ENST00000422556.1
 SPATA2
 spermatogenesis associated 2
chr19_-_44259053 0.20 ENST00000601170.1
 SMG9
 SMG9 nonsense mediated mRNA decay factor
chr12_-_11548496 0.20 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
 PRB2
PRB1
 proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr18_+_43304092 0.20 ENST00000321925.4
ENST00000587601.1
 SLC14A1
 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr3_+_137728842 0.20 ENST00000183605.5
 CLDN18
 claudin 18
chr17_+_76210267 0.20 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
 BIRC5
 baculoviral IAP repeat containing 5
chr8_+_23430157 0.19 ENST00000399967.3
 FP15737
 FP15737
chr12_+_16109519 0.18 ENST00000526530.1
 DERA
 deoxyribose-phosphate aldolase (putative)
chr22_-_32341336 0.18 ENST00000248984.3
 C22orf24
 chromosome 22 open reading frame 24
chr11_-_128457446 0.18 ENST00000392668.4
 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr7_-_766879 0.18 ENST00000537384.1
ENST00000417852.1
 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
chr3_-_114790179 0.18 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr17_+_7591747 0.17 ENST00000534050.1
 WRAP53
 WD repeat containing, antisense to TP53
chr19_-_44259136 0.17 ENST00000270066.6
 SMG9
 SMG9 nonsense mediated mRNA decay factor
chr14_+_58894706 0.17 ENST00000261244.5
 KIAA0586
 KIAA0586
chr8_-_29120580 0.16 ENST00000524189.1
 KIF13B
 kinesin family member 13B
chr1_+_179050512 0.16 ENST00000367627.3
 TOR3A
 torsin family 3, member A
chrX_-_109590174 0.16 ENST00000372054.1
 GNG5P2
 guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr1_+_43291220 0.15 ENST00000372514.3
 ERMAP
 erythroblast membrane-associated protein (Scianna blood group)
chr2_-_207023918 0.15 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_104238912 0.14 ENST00000330330.5
 AMY1B
 amylase, alpha 1B (salivary)
chr16_+_29674540 0.14 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
 SPN
QPRT
 sialophorin
quinolinate phosphoribosyltransferase
chr2_-_132249955 0.14 ENST00000309451.6
 MZT2A
 mitotic spindle organizing protein 2A
chr15_-_35047166 0.13 ENST00000290374.4
 GJD2
 gap junction protein, delta 2, 36kDa
chr3_+_39093481 0.13 ENST00000302313.5
ENST00000544962.1
ENST00000396258.3
ENST00000418020.1
 WDR48
 WD repeat domain 48
chr1_-_27998689 0.13 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
 IFI6
 interferon, alpha-inducible protein 6
chr22_+_39101728 0.13 ENST00000216044.5
ENST00000484657.1
 GTPBP1
 GTP binding protein 1
chr1_+_41157421 0.13 ENST00000372654.1
 NFYC
 nuclear transcription factor Y, gamma
chr3_+_47021168 0.13 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
 NBEAL2
 neurobeachin-like 2
chr2_+_136289030 0.12 ENST00000409478.1
ENST00000264160.4
ENST00000329971.3
ENST00000438014.1
 R3HDM1
 R3H domain containing 1
chr12_+_66218598 0.12 ENST00000541363.1
 HMGA2
 high mobility group AT-hook 2
chr14_-_58894223 0.11 ENST00000555593.1
 TIMM9
 translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_+_41157361 0.11 ENST00000427410.2
ENST00000447388.3
ENST00000425457.2
ENST00000453631.1
ENST00000456393.2
 NFYC
 nuclear transcription factor Y, gamma
chr22_-_50523760 0.11 ENST00000395876.2
 MLC1
 megalencephalic leukoencephalopathy with subcortical cysts 1
chrX_+_123094672 0.11 ENST00000354548.5
ENST00000458700.1
 STAG2
 stromal antigen 2
chrX_-_64196307 0.11 ENST00000545618.1
 ZC4H2
 zinc finger, C4H2 domain containing
chr10_+_115674530 0.10 ENST00000451472.1
 AL162407.1
 CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr6_-_55740352 0.10 ENST00000370830.3
 BMP5
 bone morphogenetic protein 5
chr4_-_119274121 0.10 ENST00000296498.3
 PRSS12
 protease, serine, 12 (neurotrypsin, motopsin)
chr11_-_77348821 0.10 ENST00000528364.1
ENST00000532069.1
ENST00000525428.1
 CLNS1A
 chloride channel, nucleotide-sensitive, 1A
chr17_+_71228793 0.10 ENST00000426147.2
 C17orf80
 chromosome 17 open reading frame 80
chr9_-_118687405 0.09 ENST00000374014.3
 LINC00474
 long intergenic non-protein coding RNA 474
chr9_-_21166659 0.09 ENST00000380225.1
 IFNA21
 interferon, alpha 21
chrX_+_123094369 0.09 ENST00000455404.1
ENST00000218089.9
 STAG2
 stromal antigen 2
chr1_-_67266939 0.09 ENST00000304526.2
 INSL5
 insulin-like 5
chrX_+_77154935 0.09 ENST00000481445.1
 COX7B
 cytochrome c oxidase subunit VIIb
chr17_-_8055747 0.08 ENST00000317276.4
ENST00000581703.1
 PER1
 period circadian clock 1
chr1_-_115292591 0.08 ENST00000438362.2
 CSDE1
 cold shock domain containing E1, RNA-binding
chrX_-_64196376 0.07 ENST00000447788.2
 ZC4H2
 zinc finger, C4H2 domain containing
chr12_-_371994 0.07 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
 SLC6A13
 solute carrier family 6 (neurotransmitter transporter), member 13
chr20_-_17539456 0.07 ENST00000544874.1
ENST00000377868.2
 BFSP1
 beaded filament structural protein 1, filensin
chr4_+_144303093 0.07 ENST00000505913.1
 GAB1
 GRB2-associated binding protein 1
chr20_-_43936937 0.07 ENST00000342716.4
ENST00000353917.5
ENST00000360607.6
ENST00000372751.4
 MATN4
 matrilin 4
chr3_-_116163830 0.07 ENST00000333617.4
 LSAMP
 limbic system-associated membrane protein
chr1_+_154401791 0.07 ENST00000476006.1
 IL6R
 interleukin 6 receptor
chr1_+_16348525 0.07 ENST00000331433.4
 CLCNKA
 chloride channel, voltage-sensitive Ka
chr11_-_77348796 0.07 ENST00000263309.3
ENST00000525064.1
 CLNS1A
 chloride channel, nucleotide-sensitive, 1A
chrX_-_64196351 0.07 ENST00000374839.3
 ZC4H2
 zinc finger, C4H2 domain containing
chr12_-_49504623 0.06 ENST00000550137.1
ENST00000547382.1
 LMBR1L
 limb development membrane protein 1-like
chr16_+_226658 0.06 ENST00000320868.5
ENST00000397797.1
 HBA1
 hemoglobin, alpha 1
chr1_+_32671236 0.06 ENST00000537469.1
ENST00000291358.6
 IQCC
 IQ motif containing C
chr1_+_42922173 0.06 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
 PPCS
 phosphopantothenoylcysteine synthetase
chr6_-_32806506 0.05 ENST00000374897.2
ENST00000452392.2
 TAP2
TAP2
 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr1_+_173793777 0.05 ENST00000239457.5
 DARS2
 aspartyl-tRNA synthetase 2, mitochondrial
chr1_-_217262969 0.05 ENST00000361525.3
 ESRRG
 estrogen-related receptor gamma
chr16_-_66952742 0.04 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
 CDH16
 cadherin 16, KSP-cadherin
chr3_-_108836977 0.04 ENST00000232603.5
 MORC1
 MORC family CW-type zinc finger 1
chr1_-_31902614 0.04 ENST00000596131.1
 AC114494.1
 HCG1787699; Uncharacterized protein
chr12_+_60058458 0.04 ENST00000548610.1
 SLC16A7
 solute carrier family 16 (monocarboxylate transporter), member 7
chrX_-_151143140 0.04 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
 GABRE
 gamma-aminobutyric acid (GABA) A receptor, epsilon
chr12_-_49504655 0.04 ENST00000551782.1
ENST00000267102.8
 LMBR1L
 limb development membrane protein 1-like
chr19_-_3600549 0.04 ENST00000589966.1
 TBXA2R
 thromboxane A2 receptor
chr3_-_58613323 0.04 ENST00000474531.1
ENST00000465970.1
 FAM107A
 family with sequence similarity 107, member A
chr1_+_41204506 0.04 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
 NFYC
 nuclear transcription factor Y, gamma
chr11_+_71791693 0.04 ENST00000289488.2
ENST00000447974.1
 LRTOMT
 leucine rich transmembrane and O-methyltransferase domain containing
chr14_+_58894103 0.03 ENST00000354386.6
ENST00000556134.1
 KIAA0586
 KIAA0586
chrX_+_144908928 0.03 ENST00000408967.2
 TMEM257
 transmembrane protein 257
chr2_+_204801471 0.03 ENST00000316386.6
ENST00000435193.1
 ICOS
 inducible T-cell co-stimulator
chr14_+_22356029 0.03 ENST00000390437.2
 TRAV12-2
 T cell receptor alpha variable 12-2
chr16_-_30441293 0.03 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
 DCTPP1
 dCTP pyrophosphatase 1
chr2_-_110371720 0.03 ENST00000356688.4
 SEPT10
 septin 10
chr6_-_160679905 0.03 ENST00000366953.3
 SLC22A2
 solute carrier family 22 (organic cation transporter), member 2
chr7_+_73507409 0.02 ENST00000538333.3
 LIMK1
 LIM domain kinase 1
chr17_-_202579 0.02 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
 RPH3AL
 rabphilin 3A-like (without C2 domains)
chr3_-_53290016 0.01 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
 TKT
 transketolase
chr3_-_114343768 0.01 ENST00000393785.2
 ZBTB20
 zinc finger and BTB domain containing 20
chr14_-_106068065 0.01 ENST00000390541.2
 IGHE
 immunoglobulin heavy constant epsilon
chr16_-_66952779 0.00 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
 CDH16
 cadherin 16, KSP-cadherin
chr7_-_156803329 0.00 ENST00000252971.6
 MNX1
 motor neuron and pancreas homeobox 1
chr12_+_7941989 0.00 ENST00000229307.4
 NANOG
 Nanog homeobox
chrX_-_110654147 0.00 ENST00000358070.4
 DCX
 doublecortin

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 15.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 0.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 6.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.4 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.3 0.8 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.2 1.6 GO:0032596 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.2 0.9 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 15.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.8 GO:0009386 translational attenuation(GO:0009386)
0.2 0.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 2.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.1 1.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.4 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 12.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.7 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 0.3 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 1.5 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.2 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 6.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.8 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 1.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.0 0.3 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:1904180 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.3 GO:0001764 neuron migration(GO:0001764)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 1.9 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.3 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.3 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.6 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 15.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 0.8 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.2 1.5 GO:0004459 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.3 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.7 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.8 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 13.2 GO:0003823 antigen binding(GO:0003823)
0.1 0.5 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 1.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0046977 peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)