ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
NKX3-2 Links Ensembl NCBI GeneCards UniProt	ENSG00000109705.7	NKX3-2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NKX3-2	hg19_v2_chr4_-_13546632_13546674	-0.36	1.7e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr10_-_98031310	5.47	ENST00000427367.2 ENST00000413476.2	BLNK	B-cell linker
chr10_-_98031265	4.34	ENST00000224337.5 ENST00000371176.2	BLNK	B-cell linker
chr5_-_149792295	2.34	ENST00000518797.1 ENST00000524315.1 ENST00000009530.7 ENST00000377795.3	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr11_+_60223225	1.88	ENST00000524807.1 ENST00000345732.4	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr14_-_106406090	1.79	ENST00000390593.2	IGHV6-1	immunoglobulin heavy variable 6-1
chr14_-_106963409	1.77	ENST00000390621.2	IGHV1-45	immunoglobulin heavy variable 1-45
chr6_-_32557610	1.72	ENST00000360004.5	HLA-DRB1	major histocompatibility complex, class II, DR beta 1
chr2_+_17721920	1.72	ENST00000295156.4	VSNL1	visinin-like 1
chr19_-_6720686	1.68	ENST00000245907.6	C3	complement component 3
chr11_+_60223312	1.64	ENST00000532491.1 ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chrX_+_105937068	1.40	ENST00000324342.3	RNF128	ring finger protein 128, E3 ubiquitin protein ligase
chr6_+_29910301	1.39	ENST00000376809.5 ENST00000376802.2	HLA-A	major histocompatibility complex, class I, A
chr10_-_47173994	1.37	ENST00000414655.2 ENST00000545298.1 ENST00000359178.4 ENST00000358140.4 ENST00000503031.1	ANXA8L1 LINC00842	annexin A8-like 1 long intergenic non-protein coding RNA 842
chr8_+_86376081	1.35	ENST00000285379.5	CA2	carbonic anhydrase II
chr15_+_81475047	1.35	ENST00000559388.1	IL16	interleukin 16
chr6_+_32821924	1.34	ENST00000374859.2 ENST00000453265.2	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9
chrX_-_107681633	1.32	ENST00000394872.2 ENST00000334504.7	COL4A6	collagen, type IV, alpha 6
chr6_-_32821599	1.26	ENST00000354258.4	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_+_47746929	1.24	ENST00000340243.6 ENST00000374277.5 ENST00000449464.2 ENST00000538825.1 ENST00000335083.5	ANXA8L2 AL603965.1	annexin A8-like 2 Protein LOC100996760
chr10_-_95360983	1.19	ENST00000371464.3	RBP4	retinol binding protein 4, plasma
chr14_+_23016437	1.18	ENST00000478163.3	TRAC	T cell receptor alpha constant
chr10_+_7745303	1.18	ENST00000429820.1 ENST00000379587.4	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr6_-_32784687	1.16	ENST00000447394.1 ENST00000438763.2	HLA-DOB	major histocompatibility complex, class II, DO beta
chr7_+_115862858	1.13	ENST00000393481.2	TES	testis derived transcript (3 LIM domains)
chr17_-_46507537	1.13	ENST00000336915.6	SKAP1	src kinase associated phosphoprotein 1
chr10_+_7745232	1.10	ENST00000358415.4	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr11_-_119993979	1.09	ENST00000524816.3 ENST00000525327.1	TRIM29	tripartite motif containing 29
chr13_-_47012325	1.09	ENST00000409879.2	KIAA0226L	KIAA0226-like
chr21_-_43816052	1.04	ENST00000398405.1	TMPRSS3	transmembrane protease, serine 3
chr12_+_4382917	1.04	ENST00000261254.3	CCND2	cyclin D2
chr19_-_7764281	0.99	ENST00000360067.4	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr5_+_156696362	0.99	ENST00000377576.3	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr11_+_128563652	0.96	ENST00000527786.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr3_-_149688502	0.93	ENST00000481767.1 ENST00000475518.1	PFN2	profilin 2
chr17_-_39928106	0.89	ENST00000540235.1	JUP	junction plakoglobin
chr1_+_35247859	0.86	ENST00000373362.3	GJB3	gap junction protein, beta 3, 31kDa
chr6_-_32731299	0.83	ENST00000435145.2 ENST00000437316.2	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr2_-_70781087	0.81	ENST00000394241.3 ENST00000295400.6	TGFA	transforming growth factor, alpha
chrX_+_13707235	0.79	ENST00000464506.1	RAB9A	RAB9A, member RAS oncogene family
chr5_+_156712372	0.78	ENST00000541131.1	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr18_+_55816546	0.76	ENST00000435432.2 ENST00000357895.5 ENST00000586263.1	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr17_+_18380051	0.76	ENST00000581545.1 ENST00000582333.1 ENST00000328114.6 ENST00000412421.2 ENST00000583322.1 ENST00000584941.1	LGALS9C	lectin, galactoside-binding, soluble, 9C
chr14_-_67859422	0.76	ENST00000556532.1	PLEK2	pleckstrin 2
chr1_+_60280458	0.72	ENST00000455990.1 ENST00000371208.3	HOOK1	hook microtubule-tethering protein 1
chr12_-_80084862	0.70	ENST00000328827.4	PAWR	PRKC, apoptosis, WT1, regulator
chr1_+_86889769	0.70	ENST00000370565.4	CLCA2	chloride channel accessory 2
chr12_+_53693466	0.69	ENST00000267103.5 ENST00000548632.1	C12orf10	chromosome 12 open reading frame 10
chr3_+_193853927	0.69	ENST00000232424.3	HES1	hes family bHLH transcription factor 1
chr19_+_16999654	0.68	ENST00000248076.3	F2RL3	coagulation factor II (thrombin) receptor-like 3
chr16_-_21289627	0.67	ENST00000396023.2 ENST00000415987.2	CRYM	crystallin, mu
chr12_+_71833550	0.65	ENST00000266674.5	LGR5	leucine-rich repeat containing G protein-coupled receptor 5
chr7_-_99573677	0.65	ENST00000292401.4	AZGP1	alpha-2-glycoprotein 1, zinc-binding
chr16_+_57406368	0.63	ENST00000006053.6 ENST00000563383.1	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr19_-_5680202	0.61	ENST00000590389.1	C19orf70	chromosome 19 open reading frame 70
chr1_-_156399184	0.59	ENST00000368243.1 ENST00000357975.4 ENST00000310027.5 ENST00000400991.2	C1orf61	chromosome 1 open reading frame 61
chr1_-_154842741	0.59	ENST00000271915.4	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr14_-_24610779	0.59	ENST00000560403.1 ENST00000419198.2 ENST00000216799.4	EMC9	ER membrane protein complex subunit 9
chr9_+_112542591	0.57	ENST00000483909.1 ENST00000314527.4 ENST00000413420.1 ENST00000302798.7 ENST00000555236.1 ENST00000510514.5	PALM2 PALM2-AKAP2 AKAP2	paralemmin 2 PALM2-AKAP2 readthrough A kinase (PRKA) anchor protein 2
chr1_-_182573514	0.57	ENST00000367558.5	RGS16	regulator of G-protein signaling 16
chr12_+_56473939	0.57	ENST00000450146.2	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_-_122296755	0.56	ENST00000289004.4	HPD	4-hydroxyphenylpyruvate dioxygenase
chr15_-_20170354	0.55	ENST00000338912.5	IGHV1OR15-9	immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr16_+_15744078	0.55	ENST00000396354.1 ENST00000570727.1	NDE1	nudE neurodevelopment protein 1
chr6_-_11382478	0.53	ENST00000397378.3 ENST00000513989.1 ENST00000508546.1 ENST00000504387.1	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr2_+_29336855	0.53	ENST00000404424.1	CLIP4	CAP-GLY domain containing linker protein family, member 4
chr14_-_21567009	0.51	ENST00000556174.1 ENST00000554478.1 ENST00000553980.1 ENST00000421093.2	ZNF219	zinc finger protein 219
chr3_+_111697843	0.50	ENST00000534857.1 ENST00000273359.3 ENST00000494817.1	ABHD10	abhydrolase domain containing 10
chr3_-_149688896	0.50	ENST00000239940.7	PFN2	profilin 2
chr19_-_6670128	0.47	ENST00000245912.3	TNFSF14	tumor necrosis factor (ligand) superfamily, member 14
chr17_-_9929581	0.46	ENST00000437099.2 ENST00000396115.2	GAS7	growth arrest-specific 7
chr14_+_72052983	0.46	ENST00000358550.2	SIPA1L1	signal-induced proliferation-associated 1 like 1
chr3_+_48507210	0.45	ENST00000433541.1 ENST00000422277.2 ENST00000436480.2 ENST00000444177.1	TREX1	three prime repair exonuclease 1
chr11_-_119993734	0.45	ENST00000533302.1	TRIM29	tripartite motif containing 29
chr14_+_21156915	0.45	ENST00000397990.4 ENST00000555597.1	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr16_-_46723066	0.45	ENST00000299138.7	VPS35	vacuolar protein sorting 35 homolog (S. cerevisiae)
chr1_-_24469602	0.44	ENST00000270800.1	IL22RA1	interleukin 22 receptor, alpha 1
chr17_+_45810594	0.44	ENST00000177694.1	TBX21	T-box 21
chr7_-_50628745	0.43	ENST00000380984.4 ENST00000357936.5 ENST00000426377.1	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr19_-_36297348	0.43	ENST00000589835.1	PRODH2	proline dehydrogenase (oxidase) 2
chr7_+_99971129	0.43	ENST00000394000.2 ENST00000350573.2	PILRA	paired immunoglobin-like type 2 receptor alpha
chr7_+_90339169	0.42	ENST00000436577.2	CDK14	cyclin-dependent kinase 14
chr18_+_59000815	0.41	ENST00000262717.4	CDH20	cadherin 20, type 2
chr22_+_38453207	0.40	ENST00000404072.3 ENST00000424694.1	PICK1	protein interacting with PRKCA 1
chr1_+_158259558	0.39	ENST00000368170.3	CD1C	CD1c molecule
chr1_-_154832316	0.38	ENST00000361147.4	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr20_-_61557821	0.36	ENST00000354665.4 ENST00000370368.1 ENST00000395343.1 ENST00000395340.1	DIDO1	death inducer-obliterator 1
chr19_+_1026566	0.36	ENST00000348419.3 ENST00000565096.2 ENST00000562958.2 ENST00000562075.2 ENST00000607102.1	CNN2	calponin 2
chr11_+_117857063	0.35	ENST00000227752.3 ENST00000541785.1 ENST00000545409.1	IL10RA	interleukin 10 receptor, alpha
chr16_-_24942273	0.35	ENST00000571406.1	ARHGAP17	Rho GTPase activating protein 17
chr12_+_56473910	0.35	ENST00000411731.2	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr4_-_141348789	0.35	ENST00000414773.1	CLGN	calmegin
chr10_-_121296045	0.35	ENST00000392865.1	RGS10	regulator of G-protein signaling 10
chr20_+_43104508	0.34	ENST00000262605.4 ENST00000372904.3	TTPAL	tocopherol (alpha) transfer protein-like
chr17_-_3500392	0.34	ENST00000571088.1 ENST00000174621.6	TRPV1	transient receptor potential cation channel, subfamily V, member 1
chr17_+_40714092	0.34	ENST00000420359.1 ENST00000449624.1 ENST00000585811.1 ENST00000585909.1 ENST00000586771.1 ENST00000421097.2 ENST00000591779.1 ENST00000587858.1 ENST00000587214.1 ENST00000587157.1 ENST00000590958.1 ENST00000393818.2	COASY	CoA synthase
chr2_-_220435963	0.34	ENST00000373876.1 ENST00000404537.1 ENST00000603926.1 ENST00000373873.4 ENST00000289656.3	OBSL1	obscurin-like 1
chr14_-_23770683	0.34	ENST00000561437.1 ENST00000559942.1 ENST00000560913.1 ENST00000559314.1 ENST00000558058.1	PPP1R3E	protein phosphatase 1, regulatory subunit 3E
chr6_-_32731243	0.33	ENST00000427449.1 ENST00000411527.1	HLA-DQB2	major histocompatibility complex, class II, DQ beta 2
chr17_-_26941179	0.33	ENST00000301037.5 ENST00000530121.1 ENST00000525510.1 ENST00000577790.1 ENST00000531839.1 ENST00000534850.1	SGK494 RP11-192H23.4	uncharacterized serine/threonine-protein kinase SgK494 Uncharacterized protein
chr5_-_150466692	0.33	ENST00000315050.7 ENST00000523338.1 ENST00000522100.1	TNIP1	TNFAIP3 interacting protein 1
chr11_+_64126614	0.33	ENST00000528057.1 ENST00000334205.4 ENST00000294261.4	RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4
chr2_+_201754050	0.33	ENST00000426253.1 ENST00000416651.1 ENST00000454952.1 ENST00000409020.1 ENST00000359683.4	NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chrX_-_31285042	0.32	ENST00000378680.2 ENST00000378723.3	DMD	dystrophin
chr17_-_67138015	0.32	ENST00000284425.2 ENST00000590645.1	ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6
chr16_-_24942411	0.32	ENST00000571843.1	ARHGAP17	Rho GTPase activating protein 17
chrX_+_44732757	0.32	ENST00000377967.4 ENST00000536777.1 ENST00000382899.4 ENST00000543216.1	KDM6A	lysine (K)-specific demethylase 6A
chr22_+_38453378	0.31	ENST00000437453.1 ENST00000356976.3	PICK1	protein interacting with PRKCA 1
chr12_+_50794730	0.31	ENST00000523389.1 ENST00000518561.1 ENST00000347328.5 ENST00000550260.1	LARP4	La ribonucleoprotein domain family, member 4
chr20_-_49547731	0.31	ENST00000396029.3	ADNP	activity-dependent neuroprotector homeobox
chr2_+_201754135	0.30	ENST00000409357.1 ENST00000409129.2	NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr5_-_115872142	0.30	ENST00000510263.1	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_+_205473720	0.30	ENST00000429964.2 ENST00000506784.1 ENST00000360066.2	CDK18	cyclin-dependent kinase 18
chr10_+_6244829	0.30	ENST00000317350.4 ENST00000379785.1 ENST00000379782.3 ENST00000360521.2 ENST00000379775.4	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_+_64879317	0.30	ENST00000526809.1 ENST00000279263.7 ENST00000524986.1 ENST00000534371.1 ENST00000540748.1 ENST00000525385.1 ENST00000345348.5 ENST00000531321.1 ENST00000529414.1 ENST00000526085.1 ENST00000530750.1	TM7SF2	transmembrane 7 superfamily member 2
chr17_+_55173933	0.29	ENST00000539273.1	AKAP1	A kinase (PRKA) anchor protein 1
chr3_-_48481518	0.29	ENST00000412398.2 ENST00000395696.1	CCDC51	coiled-coil domain containing 51
chr7_-_99573640	0.29	ENST00000411734.1	AZGP1	alpha-2-glycoprotein 1, zinc-binding
chr20_+_55966444	0.29	ENST00000356208.5 ENST00000440234.2	RBM38	RNA binding motif protein 38
chr14_+_61789382	0.28	ENST00000555082.1	PRKCH	protein kinase C, eta
chr14_+_35591735	0.28	ENST00000604948.1 ENST00000605201.1 ENST00000250377.7 ENST00000321130.10 ENST00000534898.4	KIAA0391	KIAA0391
chr3_+_124303472	0.28	ENST00000291478.5	KALRN	kalirin, RhoGEF kinase
chr1_-_173793458	0.28	ENST00000356198.2	CENPL	centromere protein L
chr17_+_4835580	0.28	ENST00000329125.5	GP1BA	glycoprotein Ib (platelet), alpha polypeptide
chr3_+_50192537	0.28	ENST00000002829.3	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_-_141348999	0.27	ENST00000325617.5	CLGN	calmegin
chr3_+_50192499	0.27	ENST00000413852.1	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr18_-_6414884	0.26	ENST00000317931.7 ENST00000284898.6 ENST00000400104.3	L3MBTL4	l(3)mbt-like 4 (Drosophila)
chr8_-_95274536	0.26	ENST00000297596.2 ENST00000396194.2	GEM	GTP binding protein overexpressed in skeletal muscle
chr2_-_220436248	0.25	ENST00000265318.4	OBSL1	obscurin-like 1
chr16_-_30457048	0.25	ENST00000500504.2 ENST00000542752.1	SEPHS2	selenophosphate synthetase 2
chr14_-_98444386	0.25	ENST00000556462.1 ENST00000556138.1	C14orf64	chromosome 14 open reading frame 64
chr11_-_22851367	0.25	ENST00000354193.4	SVIP	small VCP/p97-interacting protein
chr2_+_242167319	0.25	ENST00000601871.1	AC104841.2	HCG1777198, isoform CRA_a; PRO2900; Uncharacterized protein
chr18_+_72167096	0.24	ENST00000324301.8	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr15_-_43559055	0.24	ENST00000220420.5 ENST00000349114.4	TGM5	transglutaminase 5
chr12_-_117799446	0.24	ENST00000317775.6 ENST00000344089.3	NOS1	nitric oxide synthase 1 (neuronal)
chrX_-_107681555	0.24	ENST00000545689.1 ENST00000538570.1	COL4A6	collagen, type IV, alpha 6
chr2_+_232572361	0.23	ENST00000409321.1	PTMA	prothymosin, alpha
chrX_+_95939711	0.23	ENST00000373049.4 ENST00000324765.8	DIAPH2	diaphanous-related formin 2
chr12_-_53298841	0.23	ENST00000293308.6	KRT8	keratin 8
chr14_-_74551172	0.23	ENST00000553458.1	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chrX_-_31284974	0.22	ENST00000378702.4	DMD	dystrophin
chrX_-_31285018	0.22	ENST00000361471.4	DMD	dystrophin
chr1_-_153013588	0.22	ENST00000360379.3	SPRR2D	small proline-rich protein 2D
chr4_+_17579110	0.22	ENST00000606142.1	LAP3	leucine aminopeptidase 3
chrX_+_48660287	0.21	ENST00000444343.2 ENST00000376610.2 ENST00000334136.5 ENST00000376619.2	HDAC6	histone deacetylase 6
chr2_-_85625857	0.21	ENST00000453973.1	CAPG	capping protein (actin filament), gelsolin-like
chr20_-_49547910	0.20	ENST00000396032.3	ADNP	activity-dependent neuroprotector homeobox
chr1_+_93544821	0.20	ENST00000370303.4	MTF2	metal response element binding transcription factor 2
chr12_+_6309517	0.20	ENST00000382519.4 ENST00000009180.4	CD9	CD9 molecule
chr7_+_99971068	0.20	ENST00000198536.2 ENST00000453419.1	PILRA	paired immunoglobin-like type 2 receptor alpha
chr16_+_83986827	0.20	ENST00000393306.1 ENST00000565123.1	OSGIN1	oxidative stress induced growth inhibitor 1
chr15_-_83474806	0.20	ENST00000541889.1 ENST00000334574.8 ENST00000561368.1	FSD2	fibronectin type III and SPRY domain containing 2
chr11_-_77531858	0.20	ENST00000360355.2	RSF1	remodeling and spacing factor 1
chr16_-_27561209	0.20	ENST00000356183.4 ENST00000561623.1	GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa
chr9_-_131644202	0.20	ENST00000320665.6 ENST00000436267.2	CCBL1	cysteine conjugate-beta lyase, cytoplasmic
chr12_+_6309963	0.19	ENST00000382515.2	CD9	CD9 molecule
chr2_+_145780767	0.19	ENST00000599358.1 ENST00000596278.1 ENST00000596747.1 ENST00000608652.1 ENST00000609705.1 ENST00000608432.1 ENST00000596970.1 ENST00000602041.1 ENST00000601578.1 ENST00000596034.1 ENST00000414195.2 ENST00000594837.1	TEX41	testis expressed 41 (non-protein coding)
chr1_+_147374915	0.19	ENST00000240986.4	GJA8	gap junction protein, alpha 8, 50kDa
chr5_+_78407602	0.19	ENST00000274353.5 ENST00000524080.1	BHMT	betaine--homocysteine S-methyltransferase
chr12_+_57984965	0.19	ENST00000540759.2 ENST00000551772.1 ENST00000550465.1 ENST00000354947.5	PIP4K2C	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr12_+_71833756	0.19	ENST00000536515.1 ENST00000540815.2	LGR5	leucine-rich repeat containing G protein-coupled receptor 5
chr7_+_29237354	0.19	ENST00000546235.1	CHN2	chimerin 2
chr19_-_6767516	0.19	ENST00000245908.6	SH2D3A	SH2 domain containing 3A
chr20_+_42839722	0.19	ENST00000442383.1 ENST00000435163.1	OSER1-AS1	OSER1 antisense RNA 1 (head to head)
chr2_+_28974668	0.19	ENST00000296122.6 ENST00000395366.2	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme
chr7_+_129007964	0.19	ENST00000460109.1 ENST00000474594.1 ENST00000446212.1	AHCYL2	adenosylhomocysteinase-like 2
chrX_-_119445306	0.18	ENST00000371369.4 ENST00000440464.1 ENST00000519908.1	TMEM255A	transmembrane protein 255A
chr17_+_58755184	0.18	ENST00000589222.1 ENST00000407086.3 ENST00000390652.5	BCAS3	breast carcinoma amplified sequence 3
chr17_+_66521936	0.18	ENST00000592800.1	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_-_22009241	0.18	ENST00000380142.4	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr22_-_42343117	0.18	ENST00000407253.3 ENST00000215980.5	CENPM	centromere protein M
chr12_+_50135351	0.17	ENST00000549445.1 ENST00000550951.1 ENST00000549385.1 ENST00000548713.1 ENST00000548201.1	TMBIM6	transmembrane BAX inhibitor motif containing 6
chr16_+_55690002	0.17	ENST00000414754.3	SLC6A2	solute carrier family 6 (neurotransmitter transporter), member 2
chr14_-_90798418	0.17	ENST00000354366.3	NRDE2	NRDE-2, necessary for RNA interference, domain containing
chr6_+_166945369	0.17	ENST00000598601.1	Z98049.1	CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr5_+_176853702	0.17	ENST00000507633.1 ENST00000393576.3 ENST00000355958.5 ENST00000528793.1 ENST00000512684.1	GRK6	G protein-coupled receptor kinase 6
chr12_-_54978086	0.17	ENST00000553113.1	PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr3_-_52443799	0.17	ENST00000470173.1 ENST00000296288.5	BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr14_-_35344093	0.17	ENST00000382422.2	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr16_+_30671223	0.17	ENST00000568722.1	FBRS	fibrosin
chr10_-_99531709	0.16	ENST00000266066.3	SFRP5	secreted frizzled-related protein 5
chr16_-_47177874	0.16	ENST00000562435.1	NETO2	neuropilin (NRP) and tolloid (TLL)-like 2
chr12_+_50135327	0.16	ENST00000549966.1 ENST00000547832.1 ENST00000547187.1 ENST00000548894.1 ENST00000546914.1 ENST00000552699.1 ENST00000267115.5	TMBIM6	transmembrane BAX inhibitor motif containing 6
chr4_+_75023816	0.16	ENST00000395759.2 ENST00000331145.6 ENST00000359107.5 ENST00000325278.6	MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr12_-_10151773	0.16	ENST00000298527.6 ENST00000348658.4	CLEC1B	C-type lectin domain family 1, member B
chr14_+_50779029	0.15	ENST00000245448.6	ATP5S	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr5_-_150521192	0.15	ENST00000523714.1 ENST00000521749.1	ANXA6	annexin A6
chr7_+_16828866	0.15	ENST00000597084.1	AC073333.1	Uncharacterized protein
chr9_-_22009297	0.15	ENST00000276925.6	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr11_-_67290867	0.15	ENST00000353903.5 ENST00000294288.4	CABP2	calcium binding protein 2
chr1_+_93544791	0.15	ENST00000545708.1 ENST00000540243.1 ENST00000370298.4	MTF2	metal response element binding transcription factor 2
chr1_+_109792641	0.14	ENST00000271332.3	CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2
chr7_+_29234375	0.14	ENST00000409350.1 ENST00000495789.2 ENST00000539389.1	CHN2	chimerin 2
chr21_-_16437255	0.14	ENST00000400199.1 ENST00000400202.1	NRIP1	nuclear receptor interacting protein 1
chr14_+_45553296	0.14	ENST00000355765.6 ENST00000553605.1	PRPF39	pre-mRNA processing factor 39
chr11_+_67250490	0.14	ENST00000528641.2 ENST00000279146.3	AIP	aryl hydrocarbon receptor interacting protein
chr5_-_160279207	0.14	ENST00000327245.5	ATP10B	ATPase, class V, type 10B
chr2_-_25565377	0.14	ENST00000264709.3 ENST00000406659.3	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
chr17_-_74137374	0.14	ENST00000322957.6	FOXJ1	forkhead box J1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0002894	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.5	2.3	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.5	1.4	GO:0042938	dipeptide transport(GO:0042938)
0.4	1.2	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3	1.7	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.3	1.3	GO:0046967	cytosol to ER transport(GO:0046967)
0.2	1.2	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.2	0.7	GO:0021558	midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
0.2	1.8	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2	0.6	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.2	1.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2	0.9	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
0.2	0.7	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2	1.4	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2	0.8	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	0.4	GO:1903179	positive regulation of Wnt protein secretion(GO:0061357) regulation of late endosome to lysosome transport(GO:1902822) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of vacuolar transport(GO:1903336) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1	0.4	GO:0052314	serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.1	1.4	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	0.4	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	1.4	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.1	0.1	GO:0035995	detection of muscle stretch(GO:0035995)
0.1	0.3	GO:0050960	detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1	0.8	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405)
0.1	0.3	GO:0044501	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1	0.8	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1	0.3	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.1	0.5	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.5	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.7	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.3	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.1	0.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.6	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.2	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1	0.8	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.5	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.1	0.4	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.1	0.2	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1	0.8	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	0.3	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1	0.5	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1	0.3	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.1	3.5	GO:0042100	B cell proliferation(GO:0042100)
0.1	9.8	GO:0030183	B cell differentiation(GO:0030183)
0.1	1.0	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.5	GO:0016139	glycoside catabolic process(GO:0016139)
0.1	1.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.7	GO:0006554	lysine catabolic process(GO:0006554)
0.1	4.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.3	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.2	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	1.0	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.3	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.2	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	0.3	GO:0060701	negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1	1.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.3	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.0	1.7	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.1	GO:0048867	stem cell fate determination(GO:0048867)
0.0	0.6	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.2	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.4	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0	0.5	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.9	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0	0.6	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	2.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.5	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.1	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.0	0.3	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.2	GO:0050666	regulation of sulfur amino acid metabolic process(GO:0031335) choline catabolic process(GO:0042426) regulation of homocysteine metabolic process(GO:0050666)
0.0	0.1	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0052026	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0	0.5	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.1	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.2	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.8	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.3	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.0	2.3	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.1	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0	0.6	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:0061081	positive regulation of macrophage cytokine production(GO:0060907) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.2	GO:0009415	response to water(GO:0009415) response to hydrostatic pressure(GO:0051599)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.1	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.0	0.1	GO:0016240	autophagosome docking(GO:0016240)
0.0	0.7	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.0	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.0	0.3	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.3	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.2	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.1	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.1	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.0	0.6	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.2	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	1.1	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.2	GO:0051934	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	1.0	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.5	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.3	GO:0048536	spleen development(GO:0048536)
0.0	0.9	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.5	GO:0008285	negative regulation of cell proliferation(GO:0008285)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5	2.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	6.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.2	1.3	GO:0046979	TAP2 binding(GO:0046979)
0.2	1.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.2	1.4	GO:0004064	arylesterase activity(GO:0004064)
0.2	0.7	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2	1.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.4	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	1.0	GO:0019863	IgE binding(GO:0019863)
0.1	1.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	0.3	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	1.9	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.4	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	0.3	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	0.9	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.3	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	0.8	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.7	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.3	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.1	0.3	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.1	0.3	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1	0.2	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	1.2	GO:0016918	retinal binding(GO:0016918)
0.1	4.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	0.5	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.5	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	1.0	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.9	GO:0038132	neuregulin binding(GO:0038132)
0.1	0.2	GO:0000995	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1	0.2	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	1.7	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.2	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	0.2	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	0.2	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.1	0.5	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.2	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.3	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.3	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.1	0.2	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	0.2	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1	1.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	0.4	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	0.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	1.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.7	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.8	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	1.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.6	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.0	0.2	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	1.0	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	1.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.0	0.4	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	1.1	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	1.0	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	2.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	2.1	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.4	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	1.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.3	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.4	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.3	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	1.3	GO:0042825	TAP complex(GO:0042825)
0.2	4.0	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	1.6	GO:0005587	collagen type IV trimer(GO:0005587)
0.2	0.6	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	0.7	GO:0070695	FHF complex(GO:0070695)
0.2	1.0	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.2	1.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.4	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.1	1.4	GO:0042611	MHC protein complex(GO:0042611)
0.1	0.6	GO:1990393	3M complex(GO:1990393)
0.1	0.9	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0031213	RSF complex(GO:0031213)
0.1	0.8	GO:0016013	syntrophin complex(GO:0016013)
0.1	4.2	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.5	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	0.6	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	1.0	GO:0005922	connexon complex(GO:0005922)
0.1	0.3	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.1	0.1	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.2	GO:1990425	ryanodine receptor complex(GO:1990425)
0.0	1.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	0.5	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0	0.2	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0	0.8	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.0	4.0	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:0031010	ISWI-type complex(GO:0031010)
0.0	1.0	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	5.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.9	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.2	GO:0072357	glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0	1.4	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.9	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	1.7	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	1.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.6	GO:0005771	multivesicular body(GO:0005771)
0.0	0.7	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	1.0	GO:0043195	terminal bouton(GO:0043195)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	1.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	1.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	2.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.4	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	2.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.0	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	3.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.2	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.7	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters