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ENCODE cell lines, expression (Ernst 2011)

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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.54

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Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol Gene ID Gene Info
NOTO
ENSG00000214513.3 NOTO
VSX2
ENSG00000119614.2 VSX2
DLX2
ENSG00000115844.6 DLX2
DLX6
ENSG00000006377.9 DLX6
NKX6-1
ENSG00000163623.5 NKX6-1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX6-1hg19_v2_chr4_-_85419603_85419603-0.185.1e-01Click!
NOTOhg19_v2_chr2_+_73429386_73429386-0.175.4e-01Click!
DLX2hg19_v2_chr2_-_172967621_1729676370.155.7e-01Click!
DLX6hg19_v2_chr7_+_96634850_96634874,
hg19_v2_chr7_+_96635277_96635301		-0.097.5e-01Click!

Activity profile of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Sorted Z-values of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_81110684 2.84 ENST00000228644.3
 MYF5
 myogenic factor 5
chr12_-_6233828 1.16 ENST00000572068.1
ENST00000261405.5
 VWF
 von Willebrand factor
chr7_-_107642348 1.06 ENST00000393561.1
 LAMB1
 laminin, beta 1
chr3_+_157154578 0.96 ENST00000295927.3
 PTX3
 pentraxin 3, long
chr5_+_53751445 0.91 ENST00000302005.1
 HSPB3
 heat shock 27kDa protein 3
chr17_-_77924627 0.80 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
 TBC1D16
 TBC1 domain family, member 16
chr4_-_111563076 0.79 ENST00000354925.2
ENST00000511990.1
 PITX2
 paired-like homeodomain 2
chr4_-_186696425 0.76 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2
 sorbin and SH3 domain containing 2
chr2_-_145278475 0.73 ENST00000558170.2
 ZEB2
 zinc finger E-box binding homeobox 2
chr12_-_16761007 0.70 ENST00000354662.1
ENST00000441439.2
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr11_-_33913708 0.69 ENST00000257818.2
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr6_-_32157947 0.68 ENST00000375050.4
 PBX2
 pre-B-cell leukemia homeobox 2
chr2_-_190927447 0.58 ENST00000260950.4
 MSTN
 myostatin
chr17_-_10421853 0.57 ENST00000226207.5
 MYH1
 myosin, heavy chain 1, skeletal muscle, adult
chr1_-_227505289 0.55 ENST00000366765.3
 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
chr12_+_54378923 0.53 ENST00000303460.4
 HOXC10
 homeobox C10
chr13_-_36788718 0.52 ENST00000317764.6
ENST00000379881.3
 SOHLH2
 spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr7_+_73442487 0.52 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
 ELN
 elastin
chr10_-_92681033 0.49 ENST00000371697.3
 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
chr7_+_73442422 0.47 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
 ELN
 elastin
chr3_+_159557637 0.46 ENST00000445224.2
 SCHIP1
 schwannomin interacting protein 1
chr4_+_169418195 0.45 ENST00000261509.6
ENST00000335742.7
 PALLD
 palladin, cytoskeletal associated protein
chr3_+_173116225 0.44 ENST00000457714.1
 NLGN1
 neuroligin 1
chr21_-_40033618 0.40 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
chr4_+_41614909 0.40 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
 LIMCH1
 LIM and calponin homology domains 1
chr18_-_53089723 0.39 ENST00000561992.1
ENST00000562512.2
 TCF4
 transcription factor 4
chr7_+_73442457 0.38 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
 ELN
 elastin
chr3_-_114477787 0.38 ENST00000464560.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr6_+_151646800 0.37 ENST00000354675.6
 AKAP12
 A kinase (PRKA) anchor protein 12
chr3_+_35722487 0.36 ENST00000441454.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr11_-_2160180 0.35 ENST00000381406.4
 IGF2
 insulin-like growth factor 2 (somatomedin A)
chr19_+_50016411 0.35 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr7_+_73442102 0.32 ENST00000445912.1
ENST00000252034.7
 ELN
 elastin
chr13_-_67802549 0.31 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr12_+_26348582 0.31 ENST00000535504.1
 SSPN
 sarcospan
chr3_-_114477962 0.31 ENST00000471418.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr5_+_174151536 0.30 ENST00000239243.6
ENST00000507785.1
 MSX2
 msh homeobox 2
chr17_-_64225508 0.30 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr12_-_16759711 0.28 ENST00000447609.1
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr12_+_81101277 0.27 ENST00000228641.3
 MYF6
 myogenic factor 6 (herculin)
chr2_-_175711133 0.27 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chr7_-_27205136 0.27 ENST00000396345.1
ENST00000343483.6
 HOXA9
 homeobox A9
chr6_-_36515177 0.27 ENST00000229812.7
 STK38
 serine/threonine kinase 38
chr12_-_30887948 0.26 ENST00000433722.2
 CAPRIN2
 caprin family member 2
chr3_+_35721106 0.26 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr7_-_27169801 0.26 ENST00000511914.1
 HOXA4
 homeobox A4
chr10_-_75415825 0.25 ENST00000394810.2
 SYNPO2L
 synaptopodin 2-like
chr19_+_50016610 0.24 ENST00000596975.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr12_-_71031185 0.24 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr9_+_470288 0.24 ENST00000382303.1
 KANK1
 KN motif and ankyrin repeat domains 1
chr7_-_151217166 0.24 ENST00000496004.1
 RHEB
 Ras homolog enriched in brain
chr12_+_26348246 0.24 ENST00000422622.2
 SSPN
 sarcospan
chr3_-_141747950 0.24 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr17_+_48243352 0.23 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
 SGCA
 sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr8_+_50824233 0.23 ENST00000522124.1
 SNTG1
 syntrophin, gamma 1
chr12_+_26348429 0.23 ENST00000242729.2
 SSPN
 sarcospan
chr17_-_10325261 0.22 ENST00000403437.2
 MYH8
 myosin, heavy chain 8, skeletal muscle, perinatal
chr10_+_17270214 0.22 ENST00000544301.1
 VIM
 vimentin
chr13_+_102104980 0.22 ENST00000545560.2
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr22_-_36236623 0.22 ENST00000405409.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr4_+_3388057 0.22 ENST00000538395.1
 RGS12
 regulator of G-protein signaling 12
chr4_-_74486217 0.21 ENST00000335049.5
ENST00000307439.5
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr3_+_158787041 0.21 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
chr13_-_110438914 0.21 ENST00000375856.3
 IRS2
 insulin receptor substrate 2
chr3_-_114790179 0.20 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr8_+_77593448 0.20 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr3_-_178984759 0.20 ENST00000349697.2
ENST00000497599.1
 KCNMB3
 potassium large conductance calcium-activated channel, subfamily M beta member 3
chr3_+_158991025 0.19 ENST00000337808.6
 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
chr3_-_149293990 0.19 ENST00000472417.1
 WWTR1
 WW domain containing transcription regulator 1
chr2_+_187454749 0.19 ENST00000261023.3
ENST00000374907.3
 ITGAV
 integrin, alpha V
chr8_+_77593474 0.19 ENST00000455469.2
ENST00000050961.6
 ZFHX4
 zinc finger homeobox 4
chr2_+_169757750 0.19 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
 G6PC2
 glucose-6-phosphatase, catalytic, 2
chr16_-_28621298 0.19 ENST00000566189.1
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_-_106243451 0.18 ENST00000355610.4
ENST00000535534.1
 MORC4
 MORC family CW-type zinc finger 4
chr10_+_124320156 0.18 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
 DMBT1
 deleted in malignant brain tumors 1
chr15_+_58702742 0.18 ENST00000356113.6
ENST00000414170.3
 LIPC
 lipase, hepatic
chr17_-_10452929 0.18 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
 MYH2
 myosin, heavy chain 2, skeletal muscle, adult
chr1_+_62439037 0.18 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr11_-_129062093 0.18 ENST00000310343.9
 ARHGAP32
 Rho GTPase activating protein 32
chr16_+_22501658 0.17 ENST00000415833.2
 NPIPB5
 nuclear pore complex interacting protein family, member B5
chr22_-_36236265 0.17 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_145277569 0.17 ENST00000303660.4
 ZEB2
 zinc finger E-box binding homeobox 2
chr13_-_88323218 0.17 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
 MIR4500HG
 MIR4500 host gene (non-protein coding)
chr10_+_124320195 0.17 ENST00000359586.6
 DMBT1
 deleted in malignant brain tumors 1
chr4_+_71457970 0.17 ENST00000322937.6
 AMBN
 ameloblastin (enamel matrix protein)
chr13_+_102104952 0.17 ENST00000376180.3
 ITGBL1
 integrin, beta-like 1 (with EGF-like repeat domains)
chr18_-_53069419 0.16 ENST00000570177.2
 TCF4
 transcription factor 4
chr2_-_145275228 0.16 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr12_-_89746173 0.16 ENST00000308385.6
 DUSP6
 dual specificity phosphatase 6
chr12_-_51422017 0.16 ENST00000394904.3
 SLC11A2
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chrX_+_135251783 0.16 ENST00000394153.2
 FHL1
 four and a half LIM domains 1
chr7_-_143599207 0.15 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
 FAM115A
 family with sequence similarity 115, member A
chr21_-_35899113 0.15 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
 RCAN1
 regulator of calcineurin 1
chr16_-_29910853 0.15 ENST00000308713.5
 SEZ6L2
 seizure related 6 homolog (mouse)-like 2
chr16_-_28621312 0.15 ENST00000314752.7
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr6_-_49604545 0.15 ENST00000371175.4
ENST00000229810.7
 RHAG
 Rh-associated glycoprotein
chr4_+_86396265 0.15 ENST00000395184.1
 ARHGAP24
 Rho GTPase activating protein 24
chr6_-_100912785 0.15 ENST00000369208.3
 SIM1
 single-minded family bHLH transcription factor 1
chr20_-_56285595 0.15 ENST00000395816.3
ENST00000347215.4
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chr12_-_71031220 0.15 ENST00000334414.6
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr16_-_28621353 0.15 ENST00000567512.1
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr7_+_138145076 0.14 ENST00000343526.4
 TRIM24
 tripartite motif containing 24
chr9_+_136501478 0.13 ENST00000393056.2
ENST00000263611.2
 DBH
 dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr16_+_69345243 0.13 ENST00000254950.11
 VPS4A
 vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr2_-_152589670 0.13 ENST00000604864.1
ENST00000603639.1
 NEB
 nebulin
chr2_+_109204743 0.13 ENST00000332345.6
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr6_-_91296602 0.13 ENST00000369325.3
ENST00000369327.3
 MAP3K7
 mitogen-activated protein kinase kinase kinase 7
chr7_-_151217001 0.13 ENST00000262187.5
 RHEB
 Ras homolog enriched in brain
chr11_+_71900703 0.13 ENST00000393681.2
 FOLR1
 folate receptor 1 (adult)
chr9_-_13165457 0.13 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
 MPDZ
 multiple PDZ domain protein
chr14_-_61116168 0.13 ENST00000247182.6
 SIX1
 SIX homeobox 1
chrX_+_135251835 0.13 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr11_+_71900572 0.13 ENST00000312293.4
 FOLR1
 folate receptor 1 (adult)
chr4_-_74486347 0.13 ENST00000342081.3
 RASSF6
 Ras association (RalGDS/AF-6) domain family member 6
chr6_-_91296737 0.13 ENST00000369332.3
ENST00000369329.3
 MAP3K7
 mitogen-activated protein kinase kinase kinase 7
chr15_+_91411810 0.13 ENST00000268171.3
 FURIN
 furin (paired basic amino acid cleaving enzyme)
chr1_+_36621529 0.12 ENST00000316156.4
 MAP7D1
 MAP7 domain containing 1
chrX_+_135252050 0.12 ENST00000449474.1
ENST00000345434.3
 FHL1
 four and a half LIM domains 1
chr12_+_21207503 0.12 ENST00000545916.1
 SLCO1B7
 solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_+_206557366 0.12 ENST00000414007.1
ENST00000419187.2
 SRGAP2
 SLIT-ROBO Rho GTPase activating protein 2
chr3_-_157824292 0.11 ENST00000483851.2
 SHOX2
 short stature homeobox 2
chr9_-_136933134 0.11 ENST00000303407.7
 BRD3
 bromodomain containing 3
chr6_-_161695042 0.11 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
 AGPAT4
 1-acylglycerol-3-phosphate O-acyltransferase 4
chr21_-_39870339 0.11 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
chr7_-_99717463 0.11 ENST00000437822.2
 TAF6
 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr18_-_53257027 0.11 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
 TCF4
 transcription factor 4
chr6_-_31107127 0.11 ENST00000259845.4
 PSORS1C2
 psoriasis susceptibility 1 candidate 2
chrX_-_20236970 0.11 ENST00000379548.4
 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_-_94147385 0.10 ENST00000260502.6
 BCAR3
 breast cancer anti-estrogen resistance 3
chr18_-_53177984 0.10 ENST00000543082.1
 TCF4
 transcription factor 4
chr14_-_78083112 0.10 ENST00000216484.2
 SPTLC2
 serine palmitoyltransferase, long chain base subunit 2
chr12_+_49621658 0.10 ENST00000541364.1
 TUBA1C
 tubulin, alpha 1c
chr1_-_68698222 0.10 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
 WLS
 wntless Wnt ligand secretion mediator
chr1_-_101360331 0.10 ENST00000416479.1
ENST00000370113.3
 EXTL2
 exostosin-like glycosyltransferase 2
chr12_-_56694142 0.10 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
 CS
 citrate synthase
chr19_+_13049413 0.09 ENST00000316448.5
ENST00000588454.1
 CALR
 calreticulin
chr14_-_101295407 0.09 ENST00000596284.1
 AL117190.2
 AL117190.2
chrX_-_64196351 0.09 ENST00000374839.3
 ZC4H2
 zinc finger, C4H2 domain containing
chr11_+_125034586 0.09 ENST00000298282.9
 PKNOX2
 PBX/knotted 1 homeobox 2
chr15_-_31393910 0.09 ENST00000397795.2
ENST00000256552.6
ENST00000559179.1
 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
chr7_-_99716952 0.09 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
 TAF6
 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr9_-_14314518 0.09 ENST00000397581.2
 NFIB
 nuclear factor I/B
chr9_-_14314566 0.09 ENST00000397579.2
 NFIB
 nuclear factor I/B
chr14_+_22977587 0.09 ENST00000390504.1
 TRAJ33
 T cell receptor alpha joining 33
chr14_+_61654271 0.09 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
 PRKCH
 protein kinase C, eta
chr17_+_48823975 0.09 ENST00000513969.1
ENST00000503728.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr16_-_66764119 0.09 ENST00000569320.1
 DYNC1LI2
 dynein, cytoplasmic 1, light intermediate chain 2
chr3_-_58613323 0.08 ENST00000474531.1
ENST00000465970.1
 FAM107A
 family with sequence similarity 107, member A
chr5_+_66300446 0.08 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr2_+_201173667 0.08 ENST00000409755.3
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr1_-_94079648 0.08 ENST00000370247.3
 BCAR3
 breast cancer anti-estrogen resistance 3
chr11_-_13517565 0.08 ENST00000282091.1
ENST00000529816.1
 PTH
 parathyroid hormone
chr4_+_41614720 0.08 ENST00000509277.1
 LIMCH1
 LIM and calponin homology domains 1
chr15_+_89631381 0.08 ENST00000352732.5
 ABHD2
 abhydrolase domain containing 2
chr8_+_26150628 0.08 ENST00000523925.1
ENST00000315985.7
 PPP2R2A
 protein phosphatase 2, regulatory subunit B, alpha
chr6_-_161695074 0.08 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
 AGPAT4
 1-acylglycerol-3-phosphate O-acyltransferase 4
chr2_-_55237484 0.08 ENST00000394609.2
 RTN4
 reticulon 4
chr2_+_171034646 0.08 ENST00000409044.3
ENST00000408978.4
 MYO3B
 myosin IIIB
chr1_-_94586651 0.08 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr13_+_53602894 0.08 ENST00000219022.2
 OLFM4
 olfactomedin 4
chr1_-_95391315 0.07 ENST00000545882.1
ENST00000415017.1
 CNN3
 calponin 3, acidic
chr1_-_190446759 0.07 ENST00000367462.3
 BRINP3
 bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr15_+_58430567 0.07 ENST00000536493.1
 AQP9
 aquaporin 9
chr9_+_77230499 0.07 ENST00000396204.2
 RORB
 RAR-related orphan receptor B
chr5_-_141249154 0.07 ENST00000357517.5
ENST00000536585.1
 PCDH1
 protocadherin 1
chrX_-_64196376 0.07 ENST00000447788.2
 ZC4H2
 zinc finger, C4H2 domain containing
chr13_+_109248500 0.07 ENST00000356711.2
 MYO16
 myosin XVI
chr10_-_33623310 0.07 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
 NRP1
 neuropilin 1
chr6_-_33160231 0.07 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
 COL11A2
 collagen, type XI, alpha 2
chr6_+_151042224 0.07 ENST00000358517.2
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_-_99279928 0.07 ENST00000414521.2
 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr14_-_37051798 0.07 ENST00000258829.5
 NKX2-8
 NK2 homeobox 8
chr7_+_107224364 0.07 ENST00000491150.1
 BCAP29
 B-cell receptor-associated protein 29
chrX_+_22050546 0.07 ENST00000379374.4
 PHEX
 phosphate regulating endopeptidase homolog, X-linked
chr10_-_116444371 0.07 ENST00000533213.2
ENST00000369252.4
 ABLIM1
 actin binding LIM protein 1
chr5_-_88119580 0.07 ENST00000539796.1
 MEF2C
 myocyte enhancer factor 2C
chr6_+_39760129 0.07 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr3_-_33686743 0.07 ENST00000333778.6
ENST00000539981.1
 CLASP2
 cytoplasmic linker associated protein 2
chr1_-_204329013 0.06 ENST00000272203.3
ENST00000414478.1
 PLEKHA6
 pleckstrin homology domain containing, family A member 6
chr2_-_88285309 0.06 ENST00000420840.2
 RGPD2
 RANBP2-like and GRIP domain containing 2
chr12_+_20963632 0.06 ENST00000540853.1
ENST00000261196.2
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chrX_-_64196307 0.06 ENST00000545618.1
 ZC4H2
 zinc finger, C4H2 domain containing
chr8_-_133637624 0.06 ENST00000522789.1
 LRRC6
 leucine rich repeat containing 6
chr7_-_87342564 0.06 ENST00000265724.3
ENST00000416177.1
 ABCB1
 ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr9_-_124989804 0.06 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr11_+_65554493 0.06 ENST00000335987.3
 OVOL1
 ovo-like zinc finger 1
chr8_+_24298531 0.06 ENST00000175238.6
 ADAM7
 ADAM metallopeptidase domain 7
chr3_+_46919235 0.06 ENST00000449590.1
 PTH1R
 parathyroid hormone 1 receptor
chr12_-_118796910 0.06 ENST00000541186.1
ENST00000539872.1
 TAOK3
 TAO kinase 3
chr8_-_72268889 0.06 ENST00000388742.4
 EYA1
 eyes absent homolog 1 (Drosophila)
chr20_+_60174827 0.06 ENST00000543233.1
 CDH4
 cadherin 4, type 1, R-cadherin (retinal)
chr8_-_17579726 0.06 ENST00000381861.3
 MTUS1
 microtubule associated tumor suppressor 1
chr1_+_214161272 0.06 ENST00000498508.2
ENST00000366958.4
 PROX1
 prospero homeobox 1
chr12_+_20963647 0.06 ENST00000381545.3
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chr5_-_58295712 0.06 ENST00000317118.8
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr5_+_176811431 0.06 ENST00000512593.1
ENST00000324417.5
 SLC34A1
 solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr15_+_96869165 0.05 ENST00000421109.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr5_-_134871639 0.05 ENST00000314744.4
 NEUROG1
 neurogenin 1
chrX_-_15288154 0.05 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
 ASB9
 ankyrin repeat and SOCS box containing 9
chrX_+_46771711 0.05 ENST00000424392.1
ENST00000397189.1
 PHF16
 jade family PHD finger 3

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 4.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.3 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 1.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 2.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.3 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 3.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 3.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 1.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 0.8 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 0.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2 1.0 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 1.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.4 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.5 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.3 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.3 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.1 0.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.2 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.4 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0090611 mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.7 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.2 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) glycerol transport(GO:0015793) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0016199 axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0 1.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.5 GO:0006068 ethanol catabolic process(GO:0006068) sulfation(GO:0051923)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.0 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.0 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)