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ENCODE cell lines, expression (Ernst 2011)

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Results for NR1D1

Z-value: 0.59

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Transcription factors associated with NR1D1

Gene Symbol Gene ID Gene Info
NR1D1
ENSG00000126368.5 NR1D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1D1hg19_v2_chr17_-_38256973_382569900.448.6e-02Click!

Activity profile of NR1D1 motif

Sorted Z-values of NR1D1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1D1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_46740730 0.95 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
 F2
 coagulation factor II (thrombin)
chr9_+_103790991 0.89 ENST00000374874.3
 LPPR1
 Lipid phosphate phosphatase-related protein type 1
chr17_+_79968655 0.78 ENST00000583744.1
 ASPSCR1
 alveolar soft part sarcoma chromosome region, candidate 1
chr11_+_7534999 0.74 ENST00000528947.1
ENST00000299492.4
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_11561660 0.72 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
 GATA4
 GATA binding protein 4
chr2_-_64371546 0.64 ENST00000358912.4
 PELI1
 pellino E3 ubiquitin protein ligase 1
chr18_-_19284724 0.57 ENST00000580981.1
ENST00000289119.2
 ABHD3
 abhydrolase domain containing 3
chr6_+_31543334 0.54 ENST00000449264.2
 TNF
 tumor necrosis factor
chr1_+_20915409 0.49 ENST00000375071.3
 CDA
 cytidine deaminase
chr17_-_76128488 0.47 ENST00000322914.3
 TMC6
 transmembrane channel-like 6
chr19_-_23578220 0.44 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
 ZNF91
 zinc finger protein 91
chr17_-_3599327 0.43 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chrX_+_68725084 0.39 ENST00000252338.4
 FAM155B
 family with sequence similarity 155, member B
chr13_+_113622757 0.38 ENST00000375604.2
 MCF2L
 MCF.2 cell line derived transforming sequence-like
chr1_+_44398943 0.38 ENST00000372359.5
ENST00000414809.3
 ARTN
 artemin
chr17_-_3599492 0.38 ENST00000435558.1
ENST00000345901.3
 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
chr19_+_21324827 0.38 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
 ZNF431
 zinc finger protein 431
chr11_+_125365110 0.37 ENST00000527818.1
 AP000708.1
 AP000708.1
chr1_-_147245484 0.32 ENST00000271348.2
 GJA5
 gap junction protein, alpha 5, 40kDa
chr13_+_113622810 0.31 ENST00000397030.1
 MCF2L
 MCF.2 cell line derived transforming sequence-like
chr3_+_58223228 0.29 ENST00000478253.1
ENST00000295962.4
 ABHD6
 abhydrolase domain containing 6
chr16_+_67233007 0.29 ENST00000360833.1
ENST00000393997.2
 ELMO3
 engulfment and cell motility 3
chr17_-_38074842 0.29 ENST00000309481.7
 GSDMB
 gasdermin B
chr17_-_38074859 0.28 ENST00000520542.1
ENST00000418519.1
ENST00000394179.1
 GSDMB
 gasdermin B
chr16_+_67233412 0.27 ENST00000477898.1
 ELMO3
 engulfment and cell motility 3
chr7_+_64126535 0.27 ENST00000344930.3
 ZNF107
 zinc finger protein 107
chr14_-_23770683 0.27 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
 PPP1R3E
 protein phosphatase 1, regulatory subunit 3E
chr7_+_94139105 0.26 ENST00000297273.4
 CASD1
 CAS1 domain containing 1
chr6_+_167525277 0.26 ENST00000400926.2
 CCR6
 chemokine (C-C motif) receptor 6
chr9_+_126773880 0.25 ENST00000373615.4
 LHX2
 LIM homeobox 2
chr17_-_79139817 0.25 ENST00000326724.4
 AATK
 apoptosis-associated tyrosine kinase
chr19_-_14629224 0.23 ENST00000254322.2
 DNAJB1
 DnaJ (Hsp40) homolog, subfamily B, member 1
chr22_+_37415700 0.21 ENST00000397129.1
 MPST
 mercaptopyruvate sulfurtransferase
chr22_+_37415728 0.20 ENST00000404802.3
 MPST
 mercaptopyruvate sulfurtransferase
chr2_+_63816295 0.20 ENST00000539945.1
ENST00000544381.1
 MDH1
 malate dehydrogenase 1, NAD (soluble)
chr19_+_21264980 0.19 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
 ZNF714
 zinc finger protein 714
chr5_-_43313574 0.19 ENST00000325110.6
ENST00000433297.2
 HMGCS1
 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr7_-_128694927 0.19 ENST00000471166.1
ENST00000265388.5
 TNPO3
 transportin 3
chrX_+_24167746 0.18 ENST00000428571.1
ENST00000539115.1
 ZFX
 zinc finger protein, X-linked
chr19_-_23433144 0.18 ENST00000418100.1
ENST00000597537.1
ENST00000597037.1
 ZNF724P
 zinc finger protein 724, pseudogene
chr22_+_45898712 0.17 ENST00000455233.1
ENST00000348697.2
ENST00000402984.3
ENST00000262722.7
ENST00000327858.6
ENST00000442170.2
ENST00000340923.5
ENST00000439835.1
 FBLN1
 fibulin 1
chr22_+_37415776 0.17 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
 MPST
 mercaptopyruvate sulfurtransferase
chr3_+_171758344 0.16 ENST00000336824.4
ENST00000423424.1
 FNDC3B
 fibronectin type III domain containing 3B
chr1_+_168545711 0.16 ENST00000367818.3
 XCL1
 chemokine (C motif) ligand 1
chr19_+_22235310 0.16 ENST00000600162.1
 ZNF257
 zinc finger protein 257
chr7_-_100493744 0.16 ENST00000428317.1
ENST00000441605.1
 ACHE
 acetylcholinesterase (Yt blood group)
chr1_-_168513229 0.15 ENST00000367819.2
 XCL2
 chemokine (C motif) ligand 2
chr16_-_18468926 0.15 ENST00000545114.1
 RP11-1212A22.4
 LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chrX_+_24167828 0.14 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
 ZFX
 zinc finger protein, X-linked
chr19_-_38806560 0.13 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
 YIF1B
 Yip1 interacting factor homolog B (S. cerevisiae)
chr3_-_48723268 0.13 ENST00000439518.1
ENST00000416649.2
ENST00000341520.4
ENST00000294129.2
 NCKIPSD
 NCK interacting protein with SH3 domain
chr8_+_105235572 0.13 ENST00000523362.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chr17_-_38256973 0.13 ENST00000246672.3
 NR1D1
 nuclear receptor subfamily 1, group D, member 1
chr1_-_11865982 0.12 ENST00000418034.1
 MTHFR
 methylenetetrahydrofolate reductase (NAD(P)H)
chr2_+_63816087 0.12 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
 MDH1
 malate dehydrogenase 1, NAD (soluble)
chr2_-_89513402 0.12 ENST00000498435.1
 IGKV1-27
 immunoglobulin kappa variable 1-27
chr1_+_2398876 0.12 ENST00000449969.1
 PLCH2
 phospholipase C, eta 2
chr2_-_103353277 0.11 ENST00000258436.5
 MFSD9
 major facilitator superfamily domain containing 9
chr17_+_6899366 0.11 ENST00000251535.6
 ALOX12
 arachidonate 12-lipoxygenase
chr1_-_111991850 0.11 ENST00000411751.2
 WDR77
 WD repeat domain 77
chr15_-_81282133 0.11 ENST00000261758.4
 MESDC2
 mesoderm development candidate 2
chr7_-_142630820 0.11 ENST00000442623.1
ENST00000265310.1
 TRPV5
 transient receptor potential cation channel, subfamily V, member 5
chrY_+_2803322 0.10 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
 ZFY
 zinc finger protein, Y-linked
chr7_-_100493482 0.10 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
 ACHE
 acetylcholinesterase (Yt blood group)
chr1_-_11866034 0.10 ENST00000376590.3
 MTHFR
 methylenetetrahydrofolate reductase (NAD(P)H)
chr2_+_113342163 0.10 ENST00000409719.1
 CHCHD5
 coiled-coil-helix-coiled-coil-helix domain containing 5
chr4_+_1873100 0.09 ENST00000508803.1
 WHSC1
 Wolf-Hirschhorn syndrome candidate 1
chr7_-_128695147 0.09 ENST00000482320.1
ENST00000393245.1
ENST00000471234.1
 TNPO3
 transportin 3
chr2_-_89442621 0.09 ENST00000492167.1
 IGKV3-20
 immunoglobulin kappa variable 3-20
chr1_-_11865351 0.09 ENST00000413656.1
ENST00000376585.1
ENST00000423400.1
ENST00000431243.1
 MTHFR
 methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_168250194 0.09 ENST00000367821.3
 TBX19
 T-box 19
chr19_-_12833164 0.08 ENST00000356861.5
 TNPO2
 transportin 2
chr14_+_74815116 0.08 ENST00000256362.4
 VRTN
 vertebrae development associated
chr7_+_97736197 0.07 ENST00000297293.5
 LMTK2
 lemur tyrosine kinase 2
chr13_+_100741269 0.06 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
 PCCA
 propionyl CoA carboxylase, alpha polypeptide
chr2_-_73053126 0.06 ENST00000272427.6
ENST00000410104.1
 EXOC6B
 exocyst complex component 6B
chr7_+_139025875 0.06 ENST00000297534.6
 C7orf55
 chromosome 7 open reading frame 55
chr1_+_203764742 0.06 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
 ZC3H11A
 zinc finger CCCH-type containing 11A
chr1_+_218519577 0.06 ENST00000366930.4
ENST00000366929.4
 TGFB2
 transforming growth factor, beta 2
chr17_-_36347030 0.05 ENST00000518551.1
 TBC1D3
 TBC1 domain family, member 3
chr19_-_22605136 0.05 ENST00000357774.5
ENST00000601553.1
ENST00000593657.1
 ZNF98
 zinc finger protein 98
chr16_+_1832902 0.05 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
 NUBP2
 nucleotide binding protein 2
chr2_+_90153696 0.03 ENST00000417279.2
 IGKV3D-15
 immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr1_+_197382957 0.03 ENST00000367397.1
 CRB1
 crumbs homolog 1 (Drosophila)
chr19_-_12833361 0.03 ENST00000592287.1
 TNPO2
 transportin 2
chr19_+_21265028 0.03 ENST00000291770.7
 ZNF714
 zinc finger protein 714
chr1_-_156918806 0.03 ENST00000315174.8
 ARHGEF11
 Rho guanine nucleotide exchange factor (GEF) 11
chr1_+_110210644 0.03 ENST00000369831.2
ENST00000442650.1
ENST00000369827.3
ENST00000460717.3
ENST00000241337.4
ENST00000467579.3
ENST00000414179.2
ENST00000369829.2
 GSTM2
 glutathione S-transferase mu 2 (muscle)
chr19_-_52035044 0.02 ENST00000359982.4
ENST00000436458.1
ENST00000425629.3
ENST00000391797.3
ENST00000343300.4
 SIGLEC6
 sialic acid binding Ig-like lectin 6
chr16_-_70712229 0.02 ENST00000562883.2
 MTSS1L
 metastasis suppressor 1-like
chr2_+_203776937 0.01 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
 CARF
 calcium responsive transcription factor
chr16_+_71392616 0.01 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
 CALB2
 calbindin 2
chr19_-_19932501 0.01 ENST00000540806.2
ENST00000590766.1
ENST00000587452.1
ENST00000545006.1
ENST00000590319.1
ENST00000587461.1
ENST00000450683.2
ENST00000443905.2
ENST00000590274.1
 ZNF506
CTC-559E9.4
 zinc finger protein 506
CTC-559E9.4
chr6_-_31938700 0.01 ENST00000495340.1
 DXO
 decapping exoribonuclease
chr1_-_41131326 0.01 ENST00000372684.3
 RIMS3
 regulating synaptic membrane exocytosis 3
chr19_+_21203426 0.00 ENST00000261560.5
ENST00000599548.1
ENST00000594110.1
 ZNF430
 zinc finger protein 430
chr8_+_101162812 0.00 ENST00000353107.3
ENST00000522439.1
 POLR2K
 polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003285 septum secundum development(GO:0003285)
0.2 0.6 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 0.9 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 0.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.6 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.3 GO:0098904 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) regulation of AV node cell action potential(GO:0098904) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.3 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.2 GO:2000412 positive regulation of thymocyte migration(GO:2000412) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 0.4 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network