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ENCODE cell lines, expression (Ernst 2011)

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Results for NR1I3

Z-value: 0.45

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.7 NR1I3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161207953_1612079750.097.5e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_153330322 0.68 ENST00000368738.3
 S100A9
 S100 calcium binding protein A9
chr2_-_209118974 0.67 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
 IDH1
 isocitrate dehydrogenase 1 (NADP+), soluble
chr6_+_36097992 0.65 ENST00000211287.4
 MAPK13
 mitogen-activated protein kinase 13
chr17_-_26694979 0.48 ENST00000438614.1
 VTN
 vitronectin
chr17_-_26695013 0.47 ENST00000555059.2
 CTB-96E2.2
 Homeobox protein SEBOX
chr15_+_96876340 0.46 ENST00000453270.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr10_-_73848764 0.38 ENST00000317376.4
ENST00000412663.1
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_-_205290865 0.37 ENST00000367157.3
 NUAK2
 NUAK family, SNF1-like kinase, 2
chr18_-_19283649 0.36 ENST00000584464.1
ENST00000578270.1
 ABHD3
 abhydrolase domain containing 3
chr18_-_19284724 0.36 ENST00000580981.1
ENST00000289119.2
 ABHD3
 abhydrolase domain containing 3
chr16_-_16317321 0.34 ENST00000205557.7
ENST00000575728.1
 ABCC6
 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr17_-_53499310 0.32 ENST00000262065.3
 MMD
 monocyte to macrophage differentiation-associated
chr17_+_32582293 0.31 ENST00000580907.1
ENST00000225831.4
 CCL2
 chemokine (C-C motif) ligand 2
chr4_-_57524061 0.30 ENST00000508121.1
 HOPX
 HOP homeobox
chr1_+_44401479 0.28 ENST00000438616.3
 ARTN
 artemin
chr15_+_96875657 0.27 ENST00000559679.1
ENST00000394171.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr15_+_85523671 0.25 ENST00000310298.4
ENST00000557957.1
 PDE8A
 phosphodiesterase 8A
chrX_+_128872998 0.25 ENST00000371106.3
 XPNPEP2
 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr11_-_82611448 0.24 ENST00000393399.2
ENST00000313010.3
 PRCP
 prolylcarboxypeptidase (angiotensinase C)
chr15_+_43985084 0.23 ENST00000434505.1
ENST00000411750.1
 CKMT1A
 creatine kinase, mitochondrial 1A
chr15_+_43885252 0.21 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
 CKMT1B
 creatine kinase, mitochondrial 1B
chr7_+_100770328 0.21 ENST00000223095.4
ENST00000445463.2
 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr20_+_62339381 0.19 ENST00000355969.6
ENST00000357119.4
ENST00000431125.1
ENST00000369967.3
ENST00000328969.5
 ZGPAT
 zinc finger, CCCH-type with G patch domain
chr11_-_104480019 0.19 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
 RP11-886D15.1
 RP11-886D15.1
chr19_-_48894104 0.18 ENST00000597017.1
 KDELR1
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr7_-_31380502 0.15 ENST00000297142.3
 NEUROD6
 neuronal differentiation 6
chr16_-_75018968 0.15 ENST00000262144.6
 WDR59
 WD repeat domain 59
chr2_-_86790593 0.14 ENST00000263856.4
ENST00000409225.2
 CHMP3
 charged multivesicular body protein 3
chr1_+_15250596 0.13 ENST00000361144.5
 KAZN
 kazrin, periplakin interacting protein
chr13_-_95131923 0.13 ENST00000377028.5
ENST00000446125.1
 DCT
 dopachrome tautomerase
chr12_+_53693812 0.13 ENST00000549488.1
 C12orf10
 chromosome 12 open reading frame 10
chr1_+_154377669 0.12 ENST00000368485.3
ENST00000344086.4
 IL6R
 interleukin 6 receptor
chr6_+_108487245 0.11 ENST00000368986.4
 NR2E1
 nuclear receptor subfamily 2, group E, member 1
chrX_-_110655391 0.11 ENST00000356915.2
ENST00000356220.3
 DCX
 doublecortin
chr20_-_44007014 0.11 ENST00000372726.3
ENST00000537995.1
 TP53TG5
 TP53 target 5
chr19_-_46296011 0.10 ENST00000377735.3
ENST00000270223.6
 DMWD
 dystrophia myotonica, WD repeat containing
chr9_+_34179003 0.10 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
 UBAP1
 ubiquitin associated protein 1
chr1_+_57320437 0.10 ENST00000361249.3
 C8A
 complement component 8, alpha polypeptide
chr20_-_45142154 0.10 ENST00000347606.4
ENST00000457685.2
 ZNF334
 zinc finger protein 334
chr19_+_2977444 0.09 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
 TLE6
 transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr17_-_3301704 0.09 ENST00000322608.2
 OR1E1
 olfactory receptor, family 1, subfamily E, member 1
chr19_-_49140692 0.09 ENST00000222122.5
 DBP
 D site of albumin promoter (albumin D-box) binding protein
chr17_-_34270668 0.08 ENST00000293274.4
 LYZL6
 lysozyme-like 6
chr3_+_122103014 0.07 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
 FAM162A
 family with sequence similarity 162, member A
chr17_-_34270697 0.07 ENST00000585556.1
 LYZL6
 lysozyme-like 6
chrX_+_69674943 0.07 ENST00000542398.1
 DLG3
 discs, large homolog 3 (Drosophila)
chr11_-_59950519 0.07 ENST00000528851.1
 MS4A6A
 membrane-spanning 4-domains, subfamily A, member 6A
chr16_+_30710462 0.07 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
 SRCAP
 Snf2-related CREBBP activator protein
chr1_+_26036093 0.06 ENST00000374329.1
 MAN1C1
 mannosidase, alpha, class 1C, member 1
chr4_-_170897045 0.06 ENST00000508313.1
 RP11-205M3.3
 RP11-205M3.3
chr19_-_51336443 0.05 ENST00000598673.1
 KLK15
 kallikrein-related peptidase 15
chr19_-_49140609 0.05 ENST00000601104.1
 DBP
 D site of albumin promoter (albumin D-box) binding protein
chr19_-_6604094 0.05 ENST00000597430.2
 CD70
 CD70 molecule
chr17_-_62502399 0.05 ENST00000450599.2
ENST00000585060.1
 DDX5
 DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr1_+_145516560 0.04 ENST00000537888.1
 PEX11B
 peroxisomal biogenesis factor 11 beta
chr2_-_69098566 0.04 ENST00000295379.1
 BMP10
 bone morphogenetic protein 10
chr9_-_80646374 0.04 ENST00000286548.4
 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
chr17_-_62502639 0.04 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
 DDX5
 DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr1_+_43803475 0.04 ENST00000372470.3
ENST00000413998.2
 MPL
 myeloproliferative leukemia virus oncogene
chr14_+_22748980 0.03 ENST00000390465.2
 TRAV38-2DV8
 T cell receptor alpha variable 38-2/delta variable 8
chr1_+_145516252 0.03 ENST00000369306.3
 PEX11B
 peroxisomal biogenesis factor 11 beta
chr1_-_151119087 0.02 ENST00000341697.3
ENST00000368914.3
 SEMA6C
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr6_-_34113856 0.02 ENST00000538487.2
 GRM4
 glutamate receptor, metabotropic 4
chr3_-_50396978 0.02 ENST00000266025.3
 TMEM115
 transmembrane protein 115
chr6_-_31509714 0.01 ENST00000456662.1
ENST00000431908.1
ENST00000456976.1
ENST00000428450.1
ENST00000453105.2
ENST00000418897.1
ENST00000415382.2
ENST00000449074.2
ENST00000419020.1
ENST00000428098.1
 DDX39B
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr3_-_116164306 0.01 ENST00000490035.2
 LSAMP
 limbic system-associated membrane protein
chr16_+_577697 0.01 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
 CAPN15
 calpain 15
chr3_-_58419537 0.01 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
 PDHB
 pyruvate dehydrogenase (lipoamide) beta
chr1_-_32210275 0.01 ENST00000440175.2
 BAI2
 brain-specific angiogenesis inhibitor 2
chr1_-_225616515 0.01 ENST00000338179.2
ENST00000425080.1
 LBR
 lamin B receptor
chr14_-_77787198 0.00 ENST00000261534.4
 POMT2
 protein-O-mannosyltransferase 2
chr11_+_63137251 0.00 ENST00000310969.4
ENST00000279178.3
 SLC22A9
 solute carrier family 22 (organic anion transporter), member 9
chr6_+_96969672 0.00 ENST00000369278.4
 UFL1
 UFM1-specific ligase 1
chr9_-_91793675 0.00 ENST00000375835.4
ENST00000375830.1
 SHC3
 SHC (Src homology 2 domain containing) transforming protein 3

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.3 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1 0.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)