ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
NR2F2 Links Ensembl NCBI GeneCards UniProt	ENSG00000185551.8	NR2F2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NR2F2	hg19_v2_chr15_+_96876340_96876392	0.83	6.8e-05	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr15_+_33010175	1.28	ENST00000300177.4 ENST00000560677.1 ENST00000560830.1	GREM1	gremlin 1, DAN family BMP antagonist
chr10_+_89419370	1.19	ENST00000361175.4 ENST00000456849.1	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_-_151344172	1.16	ENST00000375734.2 ENST00000263895.4 ENST00000454202.1	RND3	Rho family GTPase 3
chr2_+_189157536	1.13	ENST00000409580.1 ENST00000409637.3	GULP1	GULP, engulfment adaptor PTB domain containing 1
chr2_+_189157498	1.13	ENST00000359135.3	GULP1	GULP, engulfment adaptor PTB domain containing 1
chr2_+_192110199	1.02	ENST00000304164.4	MYO1B	myosin IB
chr11_+_12132117	0.97	ENST00000256194.4	MICAL2	microtubule associated monooxygenase, calponin and LIM domain containing 2
chr7_+_79764104	0.94	ENST00000351004.3	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr7_-_107642348	0.93	ENST00000393561.1	LAMB1	laminin, beta 1
chr1_-_156647189	0.79	ENST00000368223.3	NES	nestin
chr10_-_15413035	0.78	ENST00000378116.4 ENST00000455654.1	FAM171A1	family with sequence similarity 171, member A1
chr1_-_20812690	0.78	ENST00000375078.3	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr20_+_43160409	0.77	ENST00000372894.3 ENST00000372892.3 ENST00000372891.3	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr6_+_142623063	0.73	ENST00000296932.8 ENST00000367609.3	GPR126	G protein-coupled receptor 126
chr6_-_2971792	0.71	ENST00000380546.3	SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr6_-_2971429	0.70	ENST00000380529.1	SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr9_+_124030338	0.69	ENST00000449773.1 ENST00000432226.1 ENST00000436847.1 ENST00000394353.2 ENST00000449733.1 ENST00000412819.1 ENST00000341272.2 ENST00000373808.2	GSN	gelsolin
chr4_-_99579733	0.68	ENST00000305798.3	TSPAN5	tetraspanin 5
chr2_-_175870085	0.68	ENST00000409156.3	CHN1	chimerin 1
chr7_-_45960850	0.67	ENST00000381083.4 ENST00000381086.5 ENST00000275521.6	IGFBP3	insulin-like growth factor binding protein 3
chr17_-_1619491	0.67	ENST00000570416.1 ENST00000575626.1 ENST00000610106.1 ENST00000608198.1 ENST00000609442.1 ENST00000334146.3 ENST00000576489.1 ENST00000608245.1 ENST00000609398.1 ENST00000608913.1 ENST00000574016.1 ENST00000571091.1 ENST00000573127.1 ENST00000609990.1 ENST00000576749.1	MIR22HG	MIR22 host gene (non-protein coding)
chr21_+_47518011	0.66	ENST00000300527.4 ENST00000357838.4 ENST00000310645.5	COL6A2	collagen, type VI, alpha 2
chr14_-_94856987	0.65	ENST00000449399.3 ENST00000404814.4	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_94857004	0.63	ENST00000557492.1 ENST00000448921.1 ENST00000437397.1 ENST00000355814.4 ENST00000393088.4	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_94856951	0.63	ENST00000553327.1 ENST00000556955.1 ENST00000557118.1 ENST00000440909.1	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_-_2971494	0.62	ENST00000380539.1	SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr13_+_113951532	0.61	ENST00000332556.4	LAMP1	lysosomal-associated membrane protein 1
chr3_+_45067659	0.60	ENST00000296130.4	CLEC3B	C-type lectin domain family 3, member B
chr19_-_43702231	0.60	ENST00000597374.1 ENST00000599371.1	PSG4	pregnancy specific beta-1-glycoprotein 4
chrX_+_99899180	0.58	ENST00000373004.3	SRPX2	sushi-repeat containing protein, X-linked 2
chr18_+_19749386	0.57	ENST00000269216.3	GATA6	GATA binding protein 6
chr19_-_6720686	0.55	ENST00000245907.6	C3	complement component 3
chr16_+_66400533	0.54	ENST00000341529.3	CDH5	cadherin 5, type 2 (vascular endothelium)
chr2_+_85811525	0.54	ENST00000306384.4	VAMP5	vesicle-associated membrane protein 5
chr5_+_66124590	0.53	ENST00000490016.2 ENST00000403666.1 ENST00000450827.1	MAST4	microtubule associated serine/threonine kinase family member 4
chr13_-_40177261	0.53	ENST00000379589.3	LHFP	lipoma HMGIC fusion partner
chr7_+_116139744	0.52	ENST00000343213.2	CAV2	caveolin 2
chr1_-_57045228	0.51	ENST00000371250.3	PPAP2B	phosphatidic acid phosphatase type 2B
chr2_+_102928009	0.51	ENST00000404917.2 ENST00000447231.1	IL1RL1	interleukin 1 receptor-like 1
chr22_-_19512893	0.50	ENST00000403084.1 ENST00000413119.2	CLDN5	claudin 5
chr11_-_27722021	0.50	ENST00000356660.4 ENST00000418212.1 ENST00000533246.1	BDNF	brain-derived neurotrophic factor
chrX_+_100333709	0.49	ENST00000372930.4	TMEM35	transmembrane protein 35
chr2_-_3523507	0.49	ENST00000327435.6	ADI1	acireductone dioxygenase 1
chr5_-_131563501	0.49	ENST00000401867.1 ENST00000379086.1 ENST00000418055.1 ENST00000453286.1 ENST00000166534.4	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr20_+_44034804	0.48	ENST00000357275.2 ENST00000372720.3	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr2_+_201450591	0.48	ENST00000374700.2	AOX1	aldehyde oxidase 1
chr14_+_61447927	0.48	ENST00000451406.1	SLC38A6	solute carrier family 38, member 6
chr11_-_61658853	0.48	ENST00000525588.1 ENST00000540820.1	FADS3	fatty acid desaturase 3
chr14_+_61447832	0.47	ENST00000354886.2 ENST00000267488.4	SLC38A6	solute carrier family 38, member 6
chr5_-_131562935	0.47	ENST00000379104.2 ENST00000379100.2 ENST00000428369.1	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr6_-_2842087	0.47	ENST00000537185.1	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chrX_+_54834791	0.47	ENST00000218439.4 ENST00000375058.1 ENST00000375060.1	MAGED2	melanoma antigen family D, 2
chr12_+_102091400	0.46	ENST00000229266.3 ENST00000549872.1	CHPT1	choline phosphotransferase 1
chr1_+_43996518	0.46	ENST00000359947.4 ENST00000438120.1	PTPRF	protein tyrosine phosphatase, receptor type, F
chr1_+_223889285	0.46	ENST00000433674.2	CAPN2	calpain 2, (m/II) large subunit
chr14_-_74959978	0.46	ENST00000541064.1	NPC2	Niemann-Pick disease, type C2
chr14_-_74960030	0.45	ENST00000553490.1 ENST00000557510.1	NPC2	Niemann-Pick disease, type C2
chrX_+_54834004	0.44	ENST00000375068.1	MAGED2	melanoma antigen family D, 2
chr22_+_35776828	0.44	ENST00000216117.8	HMOX1	heme oxygenase (decycling) 1
chr9_-_116840728	0.43	ENST00000265132.3	AMBP	alpha-1-microglobulin/bikunin precursor
chr14_-_74959994	0.43	ENST00000238633.2 ENST00000434013.2	NPC2	Niemann-Pick disease, type C2
chr6_-_2842219	0.43	ENST00000380739.5	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr6_+_53659746	0.43	ENST00000370888.1	LRRC1	leucine rich repeat containing 1
chr20_+_43343886	0.42	ENST00000190983.4	WISP2	WNT1 inducible signaling pathway protein 2
chr2_+_236402669	0.42	ENST00000409457.1 ENST00000336665.5 ENST00000304032.8	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr20_+_44034676	0.40	ENST00000372723.3 ENST00000372722.3	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_+_54694119	0.40	ENST00000456872.1 ENST00000302937.4 ENST00000429671.2	TSEN34	TSEN34 tRNA splicing endonuclease subunit
chr19_-_43269809	0.39	ENST00000406636.3 ENST00000404209.4 ENST00000306511.4	PSG8	pregnancy specific beta-1-glycoprotein 8
chr9_-_79009414	0.39	ENST00000376736.1	RFK	riboflavin kinase
chr17_-_41174424	0.38	ENST00000355653.3	VAT1	vesicle amine transport 1
chr11_-_61659006	0.37	ENST00000278829.2	FADS3	fatty acid desaturase 3
chr9_-_79009048	0.37	ENST00000490113.1	RFK	riboflavin kinase
chr10_-_90751038	0.37	ENST00000458159.1 ENST00000415557.1 ENST00000458208.1	ACTA2	actin, alpha 2, smooth muscle, aorta
chr19_-_54693401	0.36	ENST00000338624.6	MBOAT7	membrane bound O-acyltransferase domain containing 7
chrX_+_54834159	0.36	ENST00000375053.2 ENST00000347546.4 ENST00000375062.4	MAGED2	melanoma antigen family D, 2
chr12_+_52626898	0.35	ENST00000331817.5	KRT7	keratin 7
chr17_+_41006095	0.35	ENST00000591562.1 ENST00000588033.1	AOC3	amine oxidase, copper containing 3
chr20_+_44035200	0.35	ENST00000372717.1 ENST00000360981.4	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_+_6493199	0.35	ENST00000228918.4	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chrX_-_43741594	0.34	ENST00000536181.1 ENST00000378069.4	MAOB	monoamine oxidase B
chr20_+_44519948	0.34	ENST00000354880.5 ENST00000191018.5	CTSA	cathepsin A
chr19_-_42463418	0.32	ENST00000600292.1 ENST00000601078.1 ENST00000601891.1 ENST00000222008.6	RABAC1	Rab acceptor 1 (prenylated)
chr20_+_44520009	0.31	ENST00000607482.1 ENST00000372459.2	CTSA	cathepsin A
chr17_+_78075361	0.31	ENST00000577106.1 ENST00000390015.3	GAA	glucosidase, alpha; acid
chrX_+_54835493	0.31	ENST00000396224.1	MAGED2	melanoma antigen family D, 2
chr7_+_143079000	0.31	ENST00000392910.2	ZYX	zyxin
chr17_+_78075498	0.31	ENST00000302262.3	GAA	glucosidase, alpha; acid
chr16_-_53537105	0.31	ENST00000568596.1 ENST00000570004.1 ENST00000564497.1 ENST00000300245.4 ENST00000394657.7	AKTIP	AKT interacting protein
chr7_+_94139105	0.31	ENST00000297273.4	CASD1	CAS1 domain containing 1
chr6_-_105627735	0.31	ENST00000254765.3	POPDC3	popeye domain containing 3
chr11_-_33795893	0.30	ENST00000526785.1 ENST00000534136.1 ENST00000265651.3 ENST00000530401.1 ENST00000448981.2	FBXO3	F-box protein 3
chr3_-_160823040	0.30	ENST00000484127.1 ENST00000492353.1 ENST00000473142.1 ENST00000468268.1 ENST00000460353.1 ENST00000320474.4 ENST00000392781.2	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_-_80291818	0.30	ENST00000269389.3 ENST00000581691.1	SECTM1	secreted and transmembrane 1
chr2_+_201170770	0.30	ENST00000409988.3 ENST00000409385.1	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr11_-_65308082	0.29	ENST00000532661.1	LTBP3	latent transforming growth factor beta binding protein 3
chr1_-_95007193	0.29	ENST00000370207.4 ENST00000334047.7	F3	coagulation factor III (thromboplastin, tissue factor)
chr9_+_116263639	0.29	ENST00000343817.5	RGS3	regulator of G-protein signaling 3
chr1_-_33168336	0.29	ENST00000373484.3	SYNC	syncoilin, intermediate filament protein
chr2_-_235405679	0.29	ENST00000390645.2	ARL4C	ADP-ribosylation factor-like 4C
chr18_+_32556892	0.28	ENST00000591734.1 ENST00000413393.1 ENST00000589180.1 ENST00000587359.1	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr22_+_44319648	0.28	ENST00000423180.2	PNPLA3	patatin-like phospholipase domain containing 3
chr1_-_236228403	0.28	ENST00000366595.3	NID1	nidogen 1
chr13_-_52733510	0.28	ENST00000378101.2	NEK3	NIMA-related kinase 3
chr21_-_46707793	0.28	ENST00000331343.7 ENST00000349485.5	POFUT2	protein O-fucosyltransferase 2
chr3_-_45883558	0.28	ENST00000445698.1 ENST00000296135.6	LZTFL1	leucine zipper transcription factor-like 1
chr22_+_44319619	0.28	ENST00000216180.3	PNPLA3	patatin-like phospholipase domain containing 3
chr12_+_102271129	0.27	ENST00000258534.8	DRAM1	DNA-damage regulated autophagy modulator 1
chr7_+_143078652	0.27	ENST00000354434.4 ENST00000449423.2	ZYX	zyxin
chr15_-_63448973	0.27	ENST00000462430.1	RPS27L	ribosomal protein S27-like
chr2_-_86790593	0.27	ENST00000263856.4 ENST00000409225.2	CHMP3	charged multivesicular body protein 3
chr20_+_8112824	0.26	ENST00000378641.3	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr8_-_145028013	0.26	ENST00000354958.2	PLEC	plectin
chr10_-_118765081	0.26	ENST00000392903.2 ENST00000355371.4	KIAA1598	KIAA1598
chr12_+_110011571	0.26	ENST00000539696.1 ENST00000228510.3 ENST00000392727.3	MVK	mevalonate kinase
chr7_+_120629653	0.26	ENST00000450913.2 ENST00000340646.5	CPED1	cadherin-like and PC-esterase domain containing 1
chr7_+_112090483	0.25	ENST00000403825.3 ENST00000429071.1	IFRD1	interferon-related developmental regulator 1
chr17_+_79650962	0.25	ENST00000329138.4	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr11_-_2906979	0.25	ENST00000380725.1 ENST00000313407.6 ENST00000430149.2 ENST00000440480.2 ENST00000414822.3	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr6_-_131321863	0.25	ENST00000528282.1	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr21_+_47531328	0.25	ENST00000409416.1 ENST00000397763.1	COL6A2	collagen, type VI, alpha 2
chr1_+_207925391	0.24	ENST00000358170.2 ENST00000354848.1 ENST00000322918.5 ENST00000367042.1 ENST00000367041.1 ENST00000357714.1 ENST00000322875.4 ENST00000367047.1 ENST00000441839.2 ENST00000361067.1 ENST00000360212.2 ENST00000480003.1	CD46	CD46 molecule, complement regulatory protein
chr7_-_151433342	0.24	ENST00000433631.2	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chrX_+_30671476	0.24	ENST00000378946.3 ENST00000378943.3 ENST00000378945.3 ENST00000427190.1 ENST00000378941.3	GK	glycerol kinase
chr11_-_89224139	0.24	ENST00000413594.2	NOX4	NADPH oxidase 4
chr21_-_43187231	0.23	ENST00000332512.3 ENST00000352483.2	RIPK4	receptor-interacting serine-threonine kinase 4
chr5_+_150827143	0.23	ENST00000243389.3 ENST00000517945.1 ENST00000521925.1	SLC36A1	solute carrier family 36 (proton/amino acid symporter), member 1
chr15_-_66790146	0.23	ENST00000316634.5	SNAPC5	small nuclear RNA activating complex, polypeptide 5, 19kDa
chr2_-_264024	0.23	ENST00000403712.2 ENST00000356150.5 ENST00000405430.1	SH3YL1	SH3 and SYLF domain containing 1
chr7_-_151433393	0.23	ENST00000492843.1	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr6_-_46459099	0.23	ENST00000371374.1	RCAN2	regulator of calcineurin 2
chr1_-_43855479	0.23	ENST00000290663.6 ENST00000372457.4	MED8	mediator complex subunit 8
chr15_-_89456630	0.23	ENST00000268150.8	MFGE8	milk fat globule-EGF factor 8 protein
chr14_-_75536182	0.22	ENST00000555463.1	ACYP1	acylphosphatase 1, erythrocyte (common) type
chr17_-_61523535	0.22	ENST00000584031.1 ENST00000392976.1	CYB561	cytochrome b561
chr6_-_80657292	0.21	ENST00000369816.4	ELOVL4	ELOVL fatty acid elongase 4
chr6_+_7541845	0.21	ENST00000418664.2	DSP	desmoplakin
chr17_+_19437132	0.21	ENST00000436810.2 ENST00000270570.4 ENST00000457293.1 ENST00000542886.1 ENST00000575023.1 ENST00000395585.1	SLC47A1	solute carrier family 47 (multidrug and toxin extrusion), member 1
chr11_-_1587166	0.20	ENST00000331588.4	DUSP8	dual specificity phosphatase 8
chr12_-_65153175	0.20	ENST00000543646.1 ENST00000542058.1 ENST00000258145.3	GNS	glucosamine (N-acetyl)-6-sulfatase
chr16_-_89785777	0.20	ENST00000561976.1	VPS9D1	VPS9 domain containing 1
chr19_-_54693521	0.20	ENST00000391754.1 ENST00000245615.1 ENST00000431666.2	MBOAT7	membrane bound O-acyltransferase domain containing 7
chr19_+_17337027	0.20	ENST00000601529.1 ENST00000600232.1	OCEL1	occludin/ELL domain containing 1
chr4_+_8201091	0.20	ENST00000382521.3 ENST00000245105.3 ENST00000457650.2 ENST00000539824.1	SH3TC1	SH3 domain and tetratricopeptide repeats 1
chr3_+_49059038	0.20	ENST00000451378.2	NDUFAF3	NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr19_+_17337007	0.19	ENST00000215061.4	OCEL1	occludin/ELL domain containing 1
chr5_+_68530668	0.19	ENST00000506563.1	CDK7	cyclin-dependent kinase 7
chr1_-_48937838	0.19	ENST00000371847.3	SPATA6	spermatogenesis associated 6
chr1_-_43855444	0.19	ENST00000372455.4	MED8	mediator complex subunit 8
chr1_-_173174681	0.19	ENST00000367718.1	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr1_-_17307173	0.19	ENST00000438542.1 ENST00000375535.3	MFAP2	microfibrillar-associated protein 2
chr16_+_524850	0.19	ENST00000450428.1 ENST00000452814.1	RAB11FIP3	RAB11 family interacting protein 3 (class II)
chr13_-_36920872	0.19	ENST00000451493.1	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr17_-_7145475	0.19	ENST00000571129.1 ENST00000571253.1 ENST00000573928.1	GABARAP	GABA(A) receptor-associated protein
chr1_-_48937821	0.19	ENST00000396199.3	SPATA6	spermatogenesis associated 6
chr4_-_85887503	0.18	ENST00000509172.1 ENST00000322366.6 ENST00000295888.4 ENST00000502713.1	WDFY3	WD repeat and FYVE domain containing 3
chr13_-_36920615	0.18	ENST00000494062.2	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr9_-_21335240	0.18	ENST00000537938.1	KLHL9	kelch-like family member 9
chr3_-_122512619	0.18	ENST00000383659.1 ENST00000306103.2	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chrX_+_101975643	0.18	ENST00000361229.4	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr3_-_196695692	0.18	ENST00000412723.1	PIGZ	phosphatidylinositol glycan anchor biosynthesis, class Z
chr19_+_17337406	0.18	ENST00000597836.1	OCEL1	occludin/ELL domain containing 1
chr1_+_87595433	0.18	ENST00000469312.2 ENST00000490006.2	RP5-1052I5.1	long intergenic non-protein coding RNA 1140
chr16_-_30134266	0.18	ENST00000484663.1 ENST00000478356.1	MAPK3	mitogen-activated protein kinase 3
chr1_+_23037323	0.18	ENST00000544305.1 ENST00000374630.3 ENST00000400191.3 ENST00000374632.3	EPHB2	EPH receptor B2
chr3_+_42947600	0.18	ENST00000328199.6 ENST00000541208.1	ZNF662	zinc finger protein 662
chr5_+_68530697	0.18	ENST00000256443.3 ENST00000514676.1	CDK7	cyclin-dependent kinase 7
chrX_+_101975619	0.18	ENST00000457056.1	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr3_-_50329835	0.17	ENST00000429673.2	IFRD2	interferon-related developmental regulator 2
chr11_-_89224638	0.17	ENST00000535633.1 ENST00000263317.4	NOX4	NADPH oxidase 4
chr10_+_135207598	0.17	ENST00000477902.2	MTG1	mitochondrial ribosome-associated GTPase 1
chr5_-_114961858	0.17	ENST00000282382.4 ENST00000456936.3 ENST00000408996.4	TMED7-TICAM2 TMED7 TICAM2	TMED7-TICAM2 readthrough transmembrane emp24 protein transport domain containing 7 toll-like receptor adaptor molecule 2
chr10_-_52645416	0.17	ENST00000374001.2 ENST00000373997.3 ENST00000373995.3 ENST00000282641.2 ENST00000395495.1 ENST00000414883.1	A1CF	APOBEC1 complementation factor
chr5_+_131593364	0.17	ENST00000253754.3 ENST00000379018.3	PDLIM4	PDZ and LIM domain 4
chr6_+_31865552	0.17	ENST00000469372.1 ENST00000497706.1	C2	complement component 2
chr16_-_84150492	0.17	ENST00000343411.3	MBTPS1	membrane-bound transcription factor peptidase, site 1
chr1_-_244013384	0.17	ENST00000366539.1	AKT3	v-akt murine thymoma viral oncogene homolog 3
chr4_-_186697044	0.17	ENST00000437304.2	SORBS2	sorbin and SH3 domain containing 2
chr22_-_19165917	0.17	ENST00000451283.1	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr11_-_65325430	0.16	ENST00000322147.4	LTBP3	latent transforming growth factor beta binding protein 3
chr14_-_105262016	0.16	ENST00000407796.2	AKT1	v-akt murine thymoma viral oncogene homolog 1
chr12_+_132434439	0.16	ENST00000333577.4 ENST00000389561.2 ENST00000389562.2 ENST00000332482.4 ENST00000330386.6	EP400	E1A binding protein p400
chr11_-_85780086	0.16	ENST00000532317.1 ENST00000528256.1 ENST00000526033.1	PICALM	phosphatidylinositol binding clathrin assembly protein
chr1_+_160313062	0.16	ENST00000294785.5 ENST00000368063.1 ENST00000437169.1	NCSTN	nicastrin
chr11_-_85779971	0.16	ENST00000393346.3	PICALM	phosphatidylinositol binding clathrin assembly protein
chr10_-_49812997	0.16	ENST00000417912.2	ARHGAP22	Rho GTPase activating protein 22
chr11_-_89224488	0.15	ENST00000534731.1 ENST00000527626.1	NOX4	NADPH oxidase 4
chr11_-_89224299	0.15	ENST00000343727.5 ENST00000531342.1 ENST00000375979.3	NOX4	NADPH oxidase 4
chr20_-_33413416	0.15	ENST00000359003.2	NCOA6	nuclear receptor coactivator 6
chr10_-_52645379	0.15	ENST00000395489.2	A1CF	APOBEC1 complementation factor
chr9_-_21335356	0.15	ENST00000359039.4	KLHL9	kelch-like family member 9
chr8_-_57358432	0.15	ENST00000517415.1 ENST00000314922.3	PENK	proenkephalin
chr17_-_53809473	0.15	ENST00000575734.1	TMEM100	transmembrane protein 100
chr19_-_47987419	0.15	ENST00000536339.1 ENST00000595554.1 ENST00000600271.1 ENST00000338134.3	KPTN	kaptin (actin binding protein)
chr22_+_45898712	0.15	ENST00000455233.1 ENST00000348697.2 ENST00000402984.3 ENST00000262722.7 ENST00000327858.6 ENST00000442170.2 ENST00000340923.5 ENST00000439835.1	FBLN1	fibulin 1
chr4_+_159593418	0.15	ENST00000507475.1 ENST00000307738.5	ETFDH	electron-transferring-flavoprotein dehydrogenase
chr22_+_38302285	0.15	ENST00000215957.6	MICALL1	MICAL-like 1
chr14_-_105262055	0.15	ENST00000349310.3	AKT1	v-akt murine thymoma viral oncogene homolog 1
chr12_+_113659234	0.15	ENST00000551096.1 ENST00000551099.1 ENST00000335509.6 ENST00000552897.1 ENST00000550785.1 ENST00000549279.1	TPCN1	two pore segment channel 1
chr16_+_57673430	0.15	ENST00000540164.2 ENST00000568531.1	GPR56	G protein-coupled receptor 56
chr13_+_113951607	0.15	ENST00000397181.3	LAMP1	lysosomal-associated membrane protein 1

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.9	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.6	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	6.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.7	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.8	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.2	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.2	PID BMP PATHWAY	BMP receptor signaling
0.0	1.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.7	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	2.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.5	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:1900158	negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3	1.3	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.3	1.0	GO:0019417	sulfur oxidation(GO:0019417)
0.3	1.2	GO:0000103	sulfate assimilation(GO:0000103)
0.3	0.8	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.2	0.9	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2	1.6	GO:0070294	renal sodium ion absorption(GO:0070294)
0.2	0.6	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2	0.8	GO:0043323	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2	0.5	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2	0.5	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2	0.5	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.2	0.6	GO:0000023	maltose metabolic process(GO:0000023)
0.1	0.4	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1	0.7	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1	0.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	1.0	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.5	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1	0.5	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.5	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1	0.3	GO:0042391	regulation of membrane potential(GO:0042391)
0.1	0.6	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	0.3	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	0.2	GO:1904783	positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1	0.3	GO:0090427	activation of meiosis(GO:0090427)
0.1	0.5	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.3	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	1.2	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.5	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.3	GO:0007518	myoblast fate determination(GO:0007518)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.4	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.1	0.7	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1	0.4	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	1.0	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	0.2	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1	0.3	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1	0.1	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.1	0.4	GO:0090131	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.1	0.3	GO:0035524	proline transmembrane transport(GO:0035524)
0.1	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.1	GO:0045124	regulation of bone resorption(GO:0045124)
0.1	0.6	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.1	0.3	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.1	0.3	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.5	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.3	GO:0010269	response to selenium ion(GO:0010269)
0.0	0.8	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.9	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.2	GO:0035973	aggrephagy(GO:0035973)
0.0	0.3	GO:0006021	inositol biosynthetic process(GO:0006021)
0.0	0.1	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	0.3	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.2	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.1	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0	0.1	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.0	0.2	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.6	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.3	GO:0090324	negative regulation of oxidative phosphorylation(GO:0090324)
0.0	0.4	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.3	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.0	0.1	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0	0.2	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0000189	MAPK import into nucleus(GO:0000189)
0.0	0.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.2	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655)
0.0	0.3	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0	0.1	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.0	0.4	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.7	GO:0044342	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) type B pancreatic cell proliferation(GO:0044342)
0.0	0.7	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.1	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.0	0.3	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
0.0	2.2	GO:0006953	acute-phase response(GO:0006953)
0.0	0.6	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.2	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
0.0	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.2	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.3	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.0	0.3	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	1.4	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.0	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593)
0.0	0.2	GO:0005975	carbohydrate metabolic process(GO:0005975)
0.0	0.6	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.1	GO:0015879	carnitine transport(GO:0015879)
0.0	0.2	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.0	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.2	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.0	0.7	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.0	0.1	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.3	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0	0.7	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.3	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.0	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.0	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0	0.1	GO:0035897	proteolysis in other organism(GO:0035897)
0.0	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.4	GO:0051354	negative regulation of oxidoreductase activity(GO:0051354)
0.0	0.1	GO:0023035	CD40 signaling pathway(GO:0023035)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0	0.3	GO:1903541	regulation of exosomal secretion(GO:1903541)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.1	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.0	0.1	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.8	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.3	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.0	GO:1901655	cellular response to ketone(GO:1901655)
0.0	0.0	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0	0.5	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.4	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.0	GO:0050720	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0	0.1	GO:1903147	negative regulation of macromitophagy(GO:1901525) negative regulation of mitophagy(GO:1903147)
0.0	0.1	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.2	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.8	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.1	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.1	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.1	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.9	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	1.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	2.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.6	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2	0.6	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.2	1.0	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2	1.3	GO:0016015	morphogen activity(GO:0016015)
0.2	0.5	GO:0002113	interleukin-33 binding(GO:0002113)
0.2	0.5	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.1	0.4	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	0.4	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	0.5	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.1	0.4	GO:0052593	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1	0.5	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.5	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	0.7	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.4	GO:0019862	IgA binding(GO:0019862)
0.1	0.3	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1	0.7	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	0.4	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.1	0.7	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1	0.9	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.7	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.6	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1	0.6	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.3	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	1.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.3	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	0.2	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1	0.7	GO:0045159	myosin II binding(GO:0045159)
0.1	0.3	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.8	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.1	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.0	4.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	1.0	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.5	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.3	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.2	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	1.0	GO:0071949	FAD binding(GO:0071949)
0.0	0.1	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0000995	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0	0.1	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0	0.1	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0	0.2	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.2	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	0.2	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	1.2	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.0	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.2	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.3	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.1	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.3	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.4	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.3	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.4	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.0	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.5	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)
0.0	0.0	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.8	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.9	GO:0001618	virus receptor activity(GO:0001618)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0005607	laminin-2 complex(GO:0005607)
0.1	0.5	GO:0097224	sperm connecting piece(GO:0097224)
0.1	0.3	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.5	GO:0001652	granular component(GO:0001652)
0.1	0.4	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.8	GO:0032010	phagolysosome(GO:0032010) alveolar lamellar body(GO:0097208)
0.1	0.7	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.1	0.4	GO:0070985	TFIIK complex(GO:0070985)
0.1	0.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.3	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	0.2	GO:0002079	inner acrosomal membrane(GO:0002079)
0.1	0.3	GO:0070695	FHF complex(GO:0070695)
0.1	0.7	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.1	0.4	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	0.7	GO:0030478	actin cap(GO:0030478)
0.0	0.1	GO:0016938	kinesin I complex(GO:0016938)
0.0	0.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	2.8	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	3.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.5	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	2.3	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.5	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.3	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.3	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.9	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.6	GO:0016592	mediator complex(GO:0016592)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.3	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.3	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	1.3	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	1.0	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.0	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	1.0	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0032797	SMN complex(GO:0032797)
0.0	0.2	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	1.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.5	GO:0031201	SNARE complex(GO:0031201)