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ENCODE cell lines, expression (Ernst 2011)

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Results for NR4A1

Z-value: 1.03

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 NR4A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg19_v2_chr12_+_52445191_524452430.821.1e-04Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_228678550 4.74 ENST00000409189.3
ENST00000358813.4
 CCL20
 chemokine (C-C motif) ligand 20
chr11_+_116700614 3.65 ENST00000375345.1
 APOC3
 apolipoprotein C-III
chr11_+_116700600 3.63 ENST00000227667.3
 APOC3
 apolipoprotein C-III
chrX_-_43741594 2.29 ENST00000536181.1
ENST00000378069.4
 MAOB
 monoamine oxidase B
chr4_+_100495864 2.27 ENST00000265517.5
ENST00000422897.2
 MTTP
 microsomal triglyceride transfer protein
chr1_+_64059332 2.09 ENST00000540265.1
 PGM1
 phosphoglucomutase 1
chr5_-_74162605 1.92 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
 FAM169A
 family with sequence similarity 169, member A
chr17_+_1646130 1.85 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
 SERPINF2
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr6_+_31895467 1.81 ENST00000556679.1
ENST00000456570.1
 CFB
CFB
 complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895254 1.80 ENST00000299367.5
ENST00000442278.2
 C2
 complement component 2
chr10_+_101542462 1.76 ENST00000370449.4
ENST00000370434.1
 ABCC2
 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr6_+_31895480 1.73 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
 C2
CFB
 complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_+_212738676 1.67 ENST00000366981.4
ENST00000366987.2
 ATF3
 activating transcription factor 3
chr19_-_41256207 1.61 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
 C19orf54
 chromosome 19 open reading frame 54
chr11_+_7618413 1.53 ENST00000528883.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_123793633 1.43 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr14_-_95623607 1.31 ENST00000531162.1
ENST00000529720.1
ENST00000343455.3
 DICER1
 dicer 1, ribonuclease type III
chr14_-_95624227 1.28 ENST00000526495.1
 DICER1
 dicer 1, ribonuclease type III
chr6_+_64346386 1.24 ENST00000509330.1
 PHF3
 PHD finger protein 3
chr17_-_66287257 1.15 ENST00000327268.4
 SLC16A6
 solute carrier family 16, member 6
chr8_-_120685608 1.04 ENST00000427067.2
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr19_+_54926601 0.95 ENST00000301194.4
 TTYH1
 tweety family member 1
chr12_+_109577202 0.93 ENST00000377848.3
ENST00000377854.5
 ACACB
 acetyl-CoA carboxylase beta
chr19_+_54926621 0.86 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
 TTYH1
 tweety family member 1
chr1_-_111743285 0.81 ENST00000357640.4
 DENND2D
 DENN/MADD domain containing 2D
chr4_-_89744365 0.77 ENST00000513837.1
ENST00000503556.1
 FAM13A
 family with sequence similarity 13, member A
chr2_-_44223138 0.75 ENST00000260665.7
 LRPPRC
 leucine-rich pentatricopeptide repeat containing
chr4_-_89744314 0.74 ENST00000508369.1
 FAM13A
 family with sequence similarity 13, member A
chr17_+_4855053 0.74 ENST00000518175.1
 ENO3
 enolase 3 (beta, muscle)
chr4_-_89744457 0.71 ENST00000395002.2
 FAM13A
 family with sequence similarity 13, member A
chr4_-_74088800 0.69 ENST00000509867.2
 ANKRD17
 ankyrin repeat domain 17
chr1_+_174769006 0.68 ENST00000489615.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr12_-_53320245 0.68 ENST00000552150.1
 KRT8
 keratin 8
chr12_+_6644443 0.63 ENST00000396858.1
 GAPDH
 glyceraldehyde-3-phosphate dehydrogenase
chr7_+_119913688 0.62 ENST00000331113.4
 KCND2
 potassium voltage-gated channel, Shal-related subfamily, member 2
chr11_+_86748863 0.56 ENST00000340353.7
 TMEM135
 transmembrane protein 135
chrX_+_2746850 0.48 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
 GYG2
 glycogenin 2
chr2_+_162016916 0.48 ENST00000405852.1
 TANK
 TRAF family member-associated NFKB activator
chr22_-_31364187 0.48 ENST00000215862.4
ENST00000397641.3
 MORC2
 MORC family CW-type zinc finger 2
chr14_-_21567009 0.46 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
 ZNF219
 zinc finger protein 219
chr17_+_4854375 0.45 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
 ENO3
 enolase 3 (beta, muscle)
chr9_-_75567962 0.44 ENST00000297785.3
ENST00000376939.1
 ALDH1A1
 aldehyde dehydrogenase 1 family, member A1
chr2_+_162016827 0.44 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
 TANK
 TRAF family member-associated NFKB activator
chr14_-_35591433 0.43 ENST00000261475.5
ENST00000555644.1
 PPP2R3C
 protein phosphatase 2, regulatory subunit B'', gamma
chr2_+_162016804 0.40 ENST00000392749.2
ENST00000440506.1
 TANK
 TRAF family member-associated NFKB activator
chr11_+_3876859 0.40 ENST00000300737.4
 STIM1
 stromal interaction molecule 1
chr19_+_11546093 0.39 ENST00000591462.1
 PRKCSH
 protein kinase C substrate 80K-H
chr19_+_11546153 0.39 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
 PRKCSH
 protein kinase C substrate 80K-H
chr5_-_27038683 0.34 ENST00000511822.1
ENST00000231021.4
 CDH9
 cadherin 9, type 2 (T1-cadherin)
chr19_+_11546440 0.33 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
 PRKCSH
 protein kinase C substrate 80K-H
chr20_+_11898507 0.32 ENST00000378226.2
 BTBD3
 BTB (POZ) domain containing 3
chr16_+_21312170 0.31 ENST00000338573.5
ENST00000561968.1
 CRYM-AS1
 CRYM antisense RNA 1
chr2_-_207024233 0.31 ENST00000423725.1
ENST00000233190.6
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_-_207024134 0.28 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_+_178257372 0.28 ENST00000264167.4
ENST00000409888.1
 AGPS
 alkylglycerone phosphate synthase
chr22_-_51016846 0.27 ENST00000312108.7
ENST00000395650.2
 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
chr22_-_51017084 0.27 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
chr7_-_81399329 0.27 ENST00000453411.1
ENST00000444829.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr20_+_37590942 0.27 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
 DHX35
 DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr7_-_37488834 0.26 ENST00000310758.4
 ELMO1
 engulfment and cell motility 1
chr17_+_7123125 0.26 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
 ACADVL
 acyl-CoA dehydrogenase, very long chain
chr13_-_33112823 0.25 ENST00000504114.1
 N4BP2L2
 NEDD4 binding protein 2-like 2
chr7_-_72936531 0.24 ENST00000339594.4
 BAZ1B
 bromodomain adjacent to zinc finger domain, 1B
chr11_+_120971882 0.21 ENST00000392793.1
 TECTA
 tectorin alpha
chr6_-_152489484 0.21 ENST00000354674.4
ENST00000539504.1
 SYNE1
 spectrin repeat containing, nuclear envelope 1
chr3_-_30936153 0.19 ENST00000454381.3
ENST00000282538.5
 GADL1
 glutamate decarboxylase-like 1
chr17_+_41150479 0.18 ENST00000589913.1
 RPL27
 ribosomal protein L27
chr14_+_35591735 0.18 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
 KIAA0391
 KIAA0391
chr20_+_3052264 0.18 ENST00000217386.2
 OXT
 oxytocin/neurophysin I prepropeptide
chr4_+_176986978 0.16 ENST00000508596.1
ENST00000393643.2
 WDR17
 WD repeat domain 17
chr17_+_41150290 0.16 ENST00000589037.1
ENST00000253788.5
 RPL27
 ribosomal protein L27
chr14_-_21566731 0.16 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr6_-_43595039 0.14 ENST00000307114.7
 GTPBP2
 GTP binding protein 2
chr17_+_41150793 0.14 ENST00000586277.1
 RPL27
 ribosomal protein L27
chr13_-_33112956 0.14 ENST00000505213.1
 N4BP2L2
 NEDD4 binding protein 2-like 2
chr6_+_118869452 0.13 ENST00000357525.5
 PLN
 phospholamban
chr10_+_12110963 0.13 ENST00000263035.4
ENST00000437298.1
 DHTKD1
 dehydrogenase E1 and transketolase domain containing 1
chr7_-_81399355 0.13 ENST00000457544.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr17_+_79670386 0.11 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
 MRPL12
SLC25A10
SLC25A10
 mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr19_-_11639931 0.11 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
 ECSIT
 ECSIT signalling integrator
chr2_+_207024306 0.11 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
 EEF1B2
 eukaryotic translation elongation factor 1 beta 2
chr10_+_104005272 0.08 ENST00000369983.3
 GBF1
 golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr7_-_107443652 0.08 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
 SLC26A3
 solute carrier family 26 (anion exchanger), member 3
chr7_-_81399411 0.08 ENST00000423064.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_44126545 0.06 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
 CAPN11
 calpain 11
chr12_+_49687425 0.06 ENST00000257860.4
 PRPH
 peripherin
chr10_-_61666267 0.06 ENST00000263102.6
 CCDC6
 coiled-coil domain containing 6
chr1_-_33815486 0.05 ENST00000373418.3
 PHC2
 polyhomeotic homolog 2 (Drosophila)
chr7_-_81399438 0.05 ENST00000222390.5
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_+_96252706 0.04 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
 SNRPF
 small nuclear ribonucleoprotein polypeptide F
chr7_-_105517021 0.04 ENST00000318724.4
ENST00000419735.3
 ATXN7L1
 ataxin 7-like 1
chr10_+_35484793 0.04 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
 CREM
 cAMP responsive element modulator
chr15_-_42783303 0.04 ENST00000565380.1
ENST00000564754.1
 ZNF106
 zinc finger protein 106
chr4_+_71108300 0.04 ENST00000304954.3
 CSN3
 casein kappa
chr19_-_11639910 0.04 ENST00000588998.1
ENST00000586149.1
 ECSIT
 ECSIT signalling integrator
chr17_-_7123021 0.03 ENST00000399510.2
 DLG4
 discs, large homolog 4 (Drosophila)
chr19_+_17416457 0.03 ENST00000252602.1
 MRPL34
 mitochondrial ribosomal protein L34
chr18_+_43753974 0.03 ENST00000282059.6
ENST00000321319.6
 C18orf25
 chromosome 18 open reading frame 25
chr14_-_24711470 0.03 ENST00000559969.1
 TINF2
 TERF1 (TRF1)-interacting nuclear factor 2
chr11_-_8680383 0.02 ENST00000299550.6
 TRIM66
 tripartite motif containing 66
chrX_+_2746818 0.02 ENST00000398806.3
 GYG2
 glycogenin 2
chr15_+_75335604 0.01 ENST00000563393.1
 PPCDC
 phosphopantothenoylcysteine decarboxylase
chr7_+_99933730 0.01 ENST00000610247.1
 PILRB
 paired immunoglobin-like type 2 receptor beta
chr1_+_50569575 0.01 ENST00000371827.1
 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
chr11_-_113577014 0.01 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
 TMPRSS5
 transmembrane protease, serine 5

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.6 4.7 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 2.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 2.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 1.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 2.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 0.9 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.6 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.5 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 3.5 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 2.3 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 3.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 5.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 4.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.6 1.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 1.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.8 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.6 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 2.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 2.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 3.5 GO:0072562 blood microparticle(GO:0072562)
0.0 2.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 3.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0060621 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.6 4.7 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.9 2.6 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.6 1.8 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) response to antineoplastic agent(GO:0097327)
0.6 1.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 2.3 GO:0010269 response to selenium ion(GO:0010269)
0.3 3.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 1.8 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.2 0.9 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 2.3 GO:0034378 chylomicron assembly(GO:0034378)
0.2 1.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.7 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 0.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 2.1 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 1.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.8 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.1 0.4 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.7 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.3 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 1.2 GO:0061621 NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.6 GO:0032094 response to food(GO:0032094)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 1.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 5.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors