ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
ONECUT1 Links Ensembl NCBI GeneCards UniProt	ENSG00000169856.7	ONECUT1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ONECUT1	hg19_v2_chr15_-_53082178_53082209	0.84	4.6e-05	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr13_-_46679144	6.10	ENST00000181383.4	CPB2	carboxypeptidase B2 (plasma)
chr13_-_46679185	5.85	ENST00000439329.3	CPB2	carboxypeptidase B2 (plasma)
chr9_-_116840728	5.77	ENST00000265132.3	AMBP	alpha-1-microglobulin/bikunin precursor
chr12_+_69742121	4.85	ENST00000261267.2 ENST00000549690.1 ENST00000548839.1	LYZ	lysozyme
chrX_-_131623982	3.75	ENST00000370844.1	MBNL3	muscleblind-like splicing regulator 3
chr17_-_64225508	3.67	ENST00000205948.6	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr19_+_45449228	3.62	ENST00000252490.4	APOC2	apolipoprotein C-II
chr1_+_207262881	3.55	ENST00000451804.2	C4BPB	complement component 4 binding protein, beta
chr19_+_45449301	3.54	ENST00000591597.1	APOC2	apolipoprotein C-II
chr19_+_45449266	3.20	ENST00000592257.1	APOC2	apolipoprotein C-II
chr1_+_207262540	3.18	ENST00000452902.2	C4BPB	complement component 4 binding protein, beta
chr20_-_22566089	3.11	ENST00000377115.4	FOXA2	forkhead box A2
chr2_-_161350305	3.02	ENST00000348849.3	RBMS1	RNA binding motif, single stranded interacting protein 1
chr1_+_207262578	2.94	ENST00000243611.5 ENST00000367076.3	C4BPB	complement component 4 binding protein, beta
chr2_-_161349909	2.81	ENST00000392753.3	RBMS1	RNA binding motif, single stranded interacting protein 1
chr1_+_207262627	2.72	ENST00000391923.1	C4BPB	complement component 4 binding protein, beta
chr3_-_99569821	2.64	ENST00000487087.1	FILIP1L	filamin A interacting protein 1-like
chr17_+_53342311	2.61	ENST00000226067.5	HLF	hepatic leukemia factor
chr10_+_28966271	2.42	ENST00000375533.3	BAMBI	BMP and activin membrane-bound inhibitor
chr8_-_27468842	2.39	ENST00000523500.1	CLU	clusterin
chr1_+_10292308	2.20	ENST00000377081.1	KIF1B	kinesin family member 1B
chr17_-_26697304	2.16	ENST00000536498.1	VTN	vitronectin
chr17_+_41052808	2.03	ENST00000592383.1 ENST00000253801.2 ENST00000585489.1	G6PC	glucose-6-phosphatase, catalytic subunit
chr3_-_79816965	1.95	ENST00000464233.1	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr11_+_19799327	1.88	ENST00000540292.1	NAV2	neuron navigator 2
chr3_-_170744498	1.83	ENST00000382808.4 ENST00000314251.3	SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2
chr16_-_18573396	1.72	ENST00000543392.1 ENST00000381474.3 ENST00000330537.6	NOMO2	NODAL modulator 2
chrX_+_70435044	1.65	ENST00000374029.1 ENST00000374022.3 ENST00000447581.1	GJB1	gap junction protein, beta 1, 32kDa
chr16_-_75467318	1.61	ENST00000283882.3	CFDP1	craniofacial development protein 1
chr4_-_141348999	1.40	ENST00000325617.5	CLGN	calmegin
chr16_+_16326352	1.33	ENST00000399336.4 ENST00000263012.6 ENST00000538468.1	NOMO3	NODAL modulator 3
chr10_+_114133773	1.27	ENST00000354655.4	ACSL5	acyl-CoA synthetase long-chain family member 5
chr10_-_35104185	1.23	ENST00000374789.3 ENST00000374788.3 ENST00000346874.4 ENST00000374794.3 ENST00000350537.4 ENST00000374790.3 ENST00000374776.1 ENST00000374773.1 ENST00000545693.1 ENST00000545260.1 ENST00000340077.5	PARD3	par-3 family cell polarity regulator
chr2_-_85788652	1.22	ENST00000430215.3	GGCX	gamma-glutamyl carboxylase
chr1_+_57320437	1.11	ENST00000361249.3	C8A	complement component 8, alpha polypeptide
chr3_+_142315225	0.98	ENST00000457734.2 ENST00000483373.1 ENST00000475296.1 ENST00000495744.1 ENST00000476044.1 ENST00000461644.1	PLS1	plastin 1
chr15_-_99789736	0.98	ENST00000560235.1 ENST00000394132.2 ENST00000560860.1 ENST00000558078.1 ENST00000394136.1 ENST00000262074.4 ENST00000558613.1 ENST00000394130.1 ENST00000560772.1	TTC23	tetratricopeptide repeat domain 23
chr4_-_157892498	0.91	ENST00000502773.1	PDGFC	platelet derived growth factor C
chr22_-_36220420	0.89	ENST00000473487.2	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_+_52811596	0.87	ENST00000542827.1 ENST00000273283.2	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr16_-_29499154	0.85	ENST00000354563.5	RP11-231C14.4	Uncharacterized protein
chr7_-_71912046	0.84	ENST00000395276.2 ENST00000431984.1	CALN1	calneuron 1
chr7_-_5998714	0.84	ENST00000539903.1	RSPH10B	radial spoke head 10 homolog B (Chlamydomonas)
chr10_+_63661053	0.82	ENST00000279873.7	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr2_-_86850949	0.79	ENST00000237455.4	RNF103	ring finger protein 103
chr14_-_35873856	0.78	ENST00000553342.1 ENST00000216797.5 ENST00000557140.1	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr21_-_43735628	0.77	ENST00000291525.10 ENST00000518498.1	TFF3	trefoil factor 3 (intestinal)
chr7_-_121784285	0.72	ENST00000417368.2	AASS	aminoadipate-semialdehyde synthase
chr1_+_52870227	0.65	ENST00000257181.9	PRPF38A	pre-mRNA processing factor 38A
chr11_+_62623544	0.62	ENST00000377890.2 ENST00000377891.2 ENST00000377889.2	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_-_118305921	0.58	ENST00000532619.1	RP11-770J1.4	RP11-770J1.4
chr11_+_62623621	0.56	ENST00000535296.1	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr5_+_59726565	0.55	ENST00000412930.2	FKSG52	FKSG52
chr5_-_115910630	0.53	ENST00000343348.6	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_+_212738676	0.51	ENST00000366981.4 ENST00000366987.2	ATF3	activating transcription factor 3
chrX_-_33229636	0.49	ENST00000357033.4	DMD	dystrophin
chr15_-_47426320	0.49	ENST00000557832.1	FKSG62	FKSG62
chr2_+_71127699	0.47	ENST00000234392.2	VAX2	ventral anterior homeobox 2
chr10_+_51576285	0.47	ENST00000443446.1	NCOA4	nuclear receptor coactivator 4
chr4_+_187187098	0.44	ENST00000403665.2 ENST00000264692.4	F11	coagulation factor XI
chr3_+_148415571	0.42	ENST00000497524.1 ENST00000349243.3 ENST00000542281.1 ENST00000418473.2 ENST00000404754.2	AGTR1	angiotensin II receptor, type 1
chr7_-_152373216	0.41	ENST00000359321.1	XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2
chr15_-_86338100	0.41	ENST00000536947.1	KLHL25	kelch-like family member 25
chr18_-_49557	0.40	ENST00000308911.6	RP11-683L23.1	Tubulin beta-8 chain-like protein LOC260334
chr4_-_130692631	0.39	ENST00000500092.2 ENST00000509105.1	RP11-519M16.1	RP11-519M16.1
chr11_+_131240373	0.39	ENST00000374791.3 ENST00000436745.1	NTM	neurotrimin
chr19_+_5681011	0.38	ENST00000581893.1 ENST00000411793.2 ENST00000301382.4 ENST00000581773.1 ENST00000423665.2 ENST00000583928.1 ENST00000342970.2 ENST00000422535.2 ENST00000581521.1 ENST00000339423.2	HSD11B1L	hydroxysteroid (11-beta) dehydrogenase 1-like
chr2_-_55646412	0.37	ENST00000413716.2	CCDC88A	coiled-coil domain containing 88A
chr20_+_58515417	0.35	ENST00000360816.3	FAM217B	family with sequence similarity 217, member B
chr9_+_80850952	0.34	ENST00000424347.2 ENST00000415759.2 ENST00000376597.4 ENST00000277082.5 ENST00000376598.2	CEP78	centrosomal protein 78kDa
chr4_-_111563076	0.33	ENST00000354925.2 ENST00000511990.1	PITX2	paired-like homeodomain 2
chr6_-_27799305	0.33	ENST00000357549.2	HIST1H4K	histone cluster 1, H4k
chr15_-_86338134	0.33	ENST00000337975.5	KLHL25	kelch-like family member 25
chr19_-_47287990	0.31	ENST00000593713.1 ENST00000598022.1 ENST00000434726.2	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5
chr2_-_39348137	0.31	ENST00000426016.1	SOS1	son of sevenless homolog 1 (Drosophila)
chr1_+_110546700	0.30	ENST00000359172.3 ENST00000393614.4	AHCYL1	adenosylhomocysteinase-like 1
chr4_-_83483395	0.30	ENST00000515780.2	TMEM150C	transmembrane protein 150C
chr8_+_120885949	0.29	ENST00000523492.1 ENST00000286234.5	DEPTOR	DEP domain containing MTOR-interacting protein
chr17_-_17485731	0.29	ENST00000395783.1	PEMT	phosphatidylethanolamine N-methyltransferase
chr11_-_47788847	0.28	ENST00000263773.5	FNBP4	formin binding protein 4
chr2_+_27255806	0.28	ENST00000238788.9 ENST00000404032.3	TMEM214	transmembrane protein 214
chr11_+_118938485	0.28	ENST00000300793.6	VPS11	vacuolar protein sorting 11 homolog (S. cerevisiae)
chr1_-_165414414	0.28	ENST00000359842.5	RXRG	retinoid X receptor, gamma
chr4_+_123073464	0.27	ENST00000264501.4	KIAA1109	KIAA1109
chr7_+_97736197	0.26	ENST00000297293.5	LMTK2	lemur tyrosine kinase 2
chr19_+_33865218	0.25	ENST00000585933.2	CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma
chr1_-_94586651	0.24	ENST00000535735.1 ENST00000370225.3	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4
chr4_+_110834033	0.23	ENST00000509793.1 ENST00000265171.5	EGF	epidermal growth factor
chr22_+_24198890	0.23	ENST00000345044.6	SLC2A11	solute carrier family 2 (facilitated glucose transporter), member 11
chr1_+_145293371	0.22	ENST00000342960.5	NBPF10	neuroblastoma breakpoint family, member 10
chr20_+_36373032	0.21	ENST00000373473.1	CTNNBL1	catenin, beta like 1
chr7_+_129007964	0.21	ENST00000460109.1 ENST00000474594.1 ENST00000446212.1	AHCYL2	adenosylhomocysteinase-like 2
chr12_+_8995832	0.20	ENST00000541459.1	A2ML1	alpha-2-macroglobulin-like 1
chrX_-_110654147	0.18	ENST00000358070.4	DCX	doublecortin
chr12_-_56359802	0.17	ENST00000548803.1 ENST00000449260.2 ENST00000550447.1 ENST00000547137.1 ENST00000546543.1 ENST00000550464.1	PMEL	premelanosome protein
chr11_-_95657231	0.16	ENST00000409459.1 ENST00000352297.7 ENST00000393223.3 ENST00000346299.5	MTMR2	myotubularin related protein 2
chr22_+_51176624	0.15	ENST00000216139.5 ENST00000529621.1	ACR	acrosin
chr12_-_11422739	0.15	ENST00000279573.7	PRB3	proline-rich protein BstNI subfamily 3
chr1_-_1655713	0.14	ENST00000401096.2 ENST00000404249.3 ENST00000357760.2 ENST00000358779.5 ENST00000378633.1 ENST00000378635.3	CDK11A	cyclin-dependent kinase 11A
chr14_+_24422795	0.14	ENST00000313250.5 ENST00000558263.1 ENST00000543741.2 ENST00000421831.1 ENST00000397073.2 ENST00000308178.8 ENST00000382761.3 ENST00000397075.3 ENST00000397074.3 ENST00000559632.1 ENST00000558581.1	DHRS4	dehydrogenase/reductase (SDR family) member 4
chr18_-_31802056	0.13	ENST00000538587.1	NOL4	nucleolar protein 4
chr12_-_10978957	0.13	ENST00000240619.2	TAS2R10	taste receptor, type 2, member 10
chr19_+_2785458	0.12	ENST00000307741.6 ENST00000585338.1	THOP1	thimet oligopeptidase 1
chr16_-_20702578	0.11	ENST00000307493.4 ENST00000219151.4	ACSM1	acyl-CoA synthetase medium-chain family member 1
chr5_+_140800638	0.11	ENST00000398587.2 ENST00000518882.1	PCDHGA11	protocadherin gamma subfamily A, 11
chr10_+_70980051	0.10	ENST00000354624.5 ENST00000395086.2	HKDC1	hexokinase domain containing 1
chr1_-_202679535	0.10	ENST00000367268.4	SYT2	synaptotagmin II
chr13_+_52586517	0.10	ENST00000523764.1 ENST00000521508.1	ALG11	ALG11, alpha-1,2-mannosyltransferase
chr17_-_8263538	0.10	ENST00000535173.1	AC135178.1	HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr4_+_159131630	0.10	ENST00000504569.1 ENST00000509278.1 ENST00000514558.1 ENST00000503200.1	TMEM144	transmembrane protein 144
chr12_-_90024360	0.09	ENST00000393164.2	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr11_-_72385437	0.09	ENST00000418754.2 ENST00000542969.2 ENST00000334456.5	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr12_-_11422630	0.09	ENST00000381842.3 ENST00000538488.1	PRB3	proline-rich protein BstNI subfamily 3
chr12_+_74931551	0.08	ENST00000519948.2	ATXN7L3B	ataxin 7-like 3B
chr12_-_11062161	0.08	ENST00000390677.2	TAS2R13	taste receptor, type 2, member 13
chr1_+_78245303	0.08	ENST00000370791.3 ENST00000443751.2	FAM73A	family with sequence similarity 73, member A
chr15_-_89089860	0.08	ENST00000558413.1 ENST00000564406.1 ENST00000268148.8	DET1	de-etiolated homolog 1 (Arabidopsis)
chrX_-_151143140	0.07	ENST00000393914.3 ENST00000370328.3 ENST00000370325.1	GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon
chr11_+_57365150	0.07	ENST00000457869.1 ENST00000340687.6 ENST00000378323.4 ENST00000378324.2 ENST00000403558.1	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr21_-_43816052	0.07	ENST00000398405.1	TMPRSS3	transmembrane protease, serine 3
chrX_+_14547632	0.07	ENST00000218075.4	GLRA2	glycine receptor, alpha 2
chr1_+_25598989	0.07	ENST00000454452.2	RHD	Rh blood group, D antigen
chr7_-_36764142	0.06	ENST00000258749.5 ENST00000535891.1	AOAH	acyloxyacyl hydrolase (neutrophil)
chr11_+_4788500	0.06	ENST00000380390.1	MMP26	matrix metallopeptidase 26
chr5_+_128300810	0.06	ENST00000262462.4	SLC27A6	solute carrier family 27 (fatty acid transporter), member 6
chr7_-_6523688	0.05	ENST00000490996.1	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr1_-_151804222	0.05	ENST00000392697.3	RORC	RAR-related orphan receptor C
chr10_-_94003003	0.04	ENST00000412050.4	CPEB3	cytoplasmic polyadenylation element binding protein 3
chr12_+_70760056	0.04	ENST00000258111.4	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr19_+_11200038	0.03	ENST00000558518.1 ENST00000557933.1 ENST00000455727.2 ENST00000535915.1 ENST00000545707.1 ENST00000558013.1	LDLR	low density lipoprotein receptor
chr4_-_168155169	0.03	ENST00000534949.1 ENST00000535728.1	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_+_49588690	0.02	ENST00000221448.5	SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr12_-_110434183	0.02	ENST00000360185.4 ENST00000354574.4 ENST00000338373.5 ENST00000343646.5 ENST00000356259.4 ENST00000553118.1	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2
chr18_-_3880051	0.02	ENST00000584874.1	DLGAP1	discs, large (Drosophila) homolog-associated protein 1
chr13_+_52598827	0.01	ENST00000521776.2	UTP14C	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr4_-_103747011	0.01	ENST00000350435.7	UBE2D3	ubiquitin-conjugating enzyme E2D 3
chr1_+_26496362	0.01	ENST00000374266.5 ENST00000270812.5	ZNF593	zinc finger protein 593
chr11_-_67407031	0.01	ENST00000335385.3	TBX10	T-box 10
chr11_-_5531215	0.01	ENST00000311659.4	UBQLN3	ubiquilin 3

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	15.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	3.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	2.4	PID BMP PATHWAY	BMP receptor signaling
0.0	2.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.5	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	3.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	10.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	12.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	4.7	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	2.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	4.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	0.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	2.0	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	1.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	10.4	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.5	2.2	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	2.4	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.2	3.7	GO:0042627	chylomicron(GO:0042627)
0.2	1.2	GO:0033269	internode region of axon(GO:0033269)
0.2	0.5	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.2	1.9	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.0	GO:1990357	terminal web(GO:1990357)
0.1	1.1	GO:0005579	membrane attack complex(GO:0005579)
0.1	12.4	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	1.6	GO:0005922	connexon complex(GO:0005922)
0.1	0.4	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	0.8	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	4.9	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	0.5	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.2	GO:0043159	acrosomal matrix(GO:0043159)
0.0	2.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.5	GO:0044754	autolysosome(GO:0044754)
0.0	0.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.6	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	1.6	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.2	GO:0000974	Prp19 complex(GO:0000974)
0.0	2.0	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	1.9	GO:0005903	brush border(GO:0005903)
0.0	0.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0042584	chromaffin granule membrane(GO:0042584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	14.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.4	5.8	GO:0019862	IgA binding(GO:0019862)
0.8	4.9	GO:0003796	lysozyme activity(GO:0003796)
0.6	1.8	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.5	2.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4	11.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.3	1.9	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	2.4	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.4	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	2.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	1.6	GO:0005243	gap junction channel activity(GO:0005243)
0.1	1.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.3	GO:0080101	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	0.5	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	1.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.8	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	1.4	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.5	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.2	GO:0004040	amidase activity(GO:0004040) fucose binding(GO:0042806)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	1.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	5.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	2.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.4	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.7	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.5	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.9	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.7	GO:0032452	histone demethylase activity(GO:0032452)
0.0	1.2	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.8	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.5	GO:0001848	complement binding(GO:0001848)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.4	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0005046	KDEL sequence binding(GO:0005046)
0.0	0.1	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	1.7	GO:0004386	helicase activity(GO:0004386)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	10.4	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
3.0	11.9	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.4	12.4	GO:0030450	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
1.0	3.1	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.0	4.9	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.7	2.2	GO:1904647	response to rotenone(GO:1904647)
0.6	1.9	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.6	1.8	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.5	1.9	GO:0021564	vagus nerve development(GO:0021564)
0.4	2.4	GO:1902847	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4	5.8	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3	3.0	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.3	2.0	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3	2.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.2	0.7	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2	1.2	GO:0060356	leucine import(GO:0060356)
0.2	1.0	GO:1902896	terminal web assembly(GO:1902896)
0.2	1.6	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.2	0.5	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	1.6	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1	0.9	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	2.6	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	3.8	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.8	GO:0070417	cellular response to cold(GO:0070417) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.3	GO:0035993	subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1	0.4	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	0.4	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	1.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.3	GO:0010585	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1	0.5	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.3	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.1	0.4	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.1	1.2	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.3	GO:2000973	midbrain morphogenesis(GO:1904693) regulation of pro-B cell differentiation(GO:2000973)
0.1	0.4	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	1.3	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	1.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.5	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.5	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	2.3	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	1.7	GO:0031648	protein destabilization(GO:0031648)
0.0	0.9	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.8	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.5	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	1.0	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.7	GO:0016577	histone demethylation(GO:0016577)
0.0	0.3	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.9	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)