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ENCODE cell lines, expression (Ernst 2011)

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Results for OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Z-value: 0.82

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Transcription factors associated with OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Gene Symbol Gene ID Gene Info
OTP
ENSG00000171540.6 OTP
PHOX2B
ENSG00000109132.5 PHOX2B
LHX1
ENSG00000132130.7 LHX1
LMX1A
ENSG00000162761.10 LMX1A
LHX5
ENSG00000089116.3 LHX5
HOXC4
ENSG00000198353.6 HOXC4
HOXC4
ENSG00000273266.1 HOXC4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC4hg19_v2_chr12_+_54447637_54447661-0.533.6e-02Click!
LHX1hg19_v2_chr17_+_35294075_35294102-0.523.9e-02Click!
PHOX2Bhg19_v2_chr4_-_41750922_41750987-0.214.2e-01Click!
LHX5hg19_v2_chr12_-_113909877_113909877-0.039.2e-01Click!

Activity profile of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 motif

Sorted Z-values of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_1674982 5.82 ENST00000572048.1
ENST00000573763.1
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_-_28634874 2.91 ENST00000395609.1
ENST00000350842.4
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_+_50016610 2.83 ENST00000596975.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr19_+_50016411 2.82 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
 FCGRT
 Fc fragment of IgG, receptor, transporter, alpha
chr5_+_95066823 2.28 ENST00000506817.1
ENST00000379982.3
 RHOBTB3
 Rho-related BTB domain containing 3
chr3_+_157154578 2.06 ENST00000295927.3
 PTX3
 pentraxin 3, long
chr7_+_134528635 1.71 ENST00000445569.2
 CALD1
 caldesmon 1
chr11_-_63376013 1.56 ENST00000540943.1
 PLA2G16
 phospholipase A2, group XVI
chr12_+_26348246 1.55 ENST00000422622.2
 SSPN
 sarcospan
chr10_+_94451574 1.52 ENST00000492654.2
 HHEX
 hematopoietically expressed homeobox
chr7_+_138145076 1.28 ENST00000343526.4
 TRIM24
 tripartite motif containing 24
chr17_-_64225508 1.28 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr16_-_30122717 1.21 ENST00000566613.1
 GDPD3
 glycerophosphodiester phosphodiesterase domain containing 3
chr20_-_33735070 1.15 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
 EDEM2
 ER degradation enhancer, mannosidase alpha-like 2
chr7_-_87342564 1.10 ENST00000265724.3
ENST00000416177.1
 ABCB1
 ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr12_+_26348429 1.09 ENST00000242729.2
 SSPN
 sarcospan
chr1_-_92371839 1.00 ENST00000370399.2
 TGFBR3
 transforming growth factor, beta receptor III
chr15_+_58702742 1.00 ENST00000356113.6
ENST00000414170.3
 LIPC
 lipase, hepatic
chr11_+_114168085 0.99 ENST00000541754.1
 NNMT
 nicotinamide N-methyltransferase
chr3_-_149293990 0.92 ENST00000472417.1
 WWTR1
 WW domain containing transcription regulator 1
chr7_+_102553430 0.91 ENST00000339431.4
ENST00000249377.4
 LRRC17
 leucine rich repeat containing 17
chr12_+_26348582 0.85 ENST00000535504.1
 SSPN
 sarcospan
chr1_+_117544366 0.72 ENST00000256652.4
ENST00000369470.1
 CD101
 CD101 molecule
chr10_-_75415825 0.72 ENST00000394810.2
 SYNPO2L
 synaptopodin 2-like
chr1_-_57045228 0.69 ENST00000371250.3
 PPAP2B
 phosphatidic acid phosphatase type 2B
chr7_-_143599207 0.69 ENST00000355951.2
ENST00000479870.1
ENST00000478172.1
 FAM115A
 family with sequence similarity 115, member A
chr4_+_155484155 0.66 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr2_+_152214098 0.60 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr7_-_107642348 0.59 ENST00000393561.1
 LAMB1
 laminin, beta 1
chr19_-_51920952 0.58 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
 SIGLEC10
 sialic acid binding Ig-like lectin 10
chr3_-_114477962 0.52 ENST00000471418.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr2_-_190927447 0.52 ENST00000260950.4
 MSTN
 myostatin
chr3_-_114477787 0.50 ENST00000464560.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr12_+_64798095 0.50 ENST00000332707.5
 XPOT
 exportin, tRNA
chr3_-_185538849 0.50 ENST00000421047.2
 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
chr11_-_327537 0.48 ENST00000602735.1
 IFITM3
 interferon induced transmembrane protein 3
chr4_-_185275104 0.47 ENST00000317596.3
 RP11-290F5.2
 RP11-290F5.2
chr3_-_99569821 0.46 ENST00000487087.1
 FILIP1L
 filamin A interacting protein 1-like
chr4_+_155484103 0.44 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr19_-_14064114 0.44 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
 PODNL1
 podocan-like 1
chr9_+_125132803 0.43 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_109935819 0.38 ENST00000538502.1
 SORT1
 sortilin 1
chr3_+_12329397 0.38 ENST00000397015.2
 PPARG
 peroxisome proliferator-activated receptor gamma
chr7_+_150020329 0.38 ENST00000323078.7
 LRRC61
 leucine rich repeat containing 61
chr14_+_50234309 0.36 ENST00000298307.5
 KLHDC2
 kelch domain containing 2
chr3_-_149095652 0.36 ENST00000305366.3
 TM4SF1
 transmembrane 4 L six family member 1
chr1_-_153518270 0.34 ENST00000354332.4
ENST00000368716.4
 S100A4
 S100 calcium binding protein A4
chr7_+_150020363 0.32 ENST00000359623.4
ENST00000493307.1
 LRRC61
 leucine rich repeat containing 61
chr6_-_32157947 0.31 ENST00000375050.4
 PBX2
 pre-B-cell leukemia homeobox 2
chr17_-_46688334 0.31 ENST00000239165.7
 HOXB7
 homeobox B7
chr7_+_73868120 0.31 ENST00000265755.3
 GTF2IRD1
 GTF2I repeat domain containing 1
chr7_+_73868439 0.30 ENST00000424337.2
 GTF2IRD1
 GTF2I repeat domain containing 1
chr13_-_38172863 0.28 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
 POSTN
 periostin, osteoblast specific factor
chr5_-_176889381 0.28 ENST00000393563.4
ENST00000512501.1
 DBN1
 drebrin 1
chr2_+_90211643 0.27 ENST00000390277.2
 IGKV3D-11
 immunoglobulin kappa variable 3D-11
chr8_-_90769422 0.26 ENST00000524190.1
ENST00000523859.1
 RP11-37B2.1
 RP11-37B2.1
chr2_+_187454749 0.25 ENST00000261023.3
ENST00000374907.3
 ITGAV
 integrin, alpha V
chr3_+_12329358 0.24 ENST00000309576.6
 PPARG
 peroxisome proliferator-activated receptor gamma
chr2_+_109237717 0.24 ENST00000409441.1
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr6_+_26440700 0.23 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
 BTN3A3
 butyrophilin, subfamily 3, member A3
chr1_-_101360331 0.22 ENST00000416479.1
ENST00000370113.3
 EXTL2
 exostosin-like glycosyltransferase 2
chr6_-_133035185 0.21 ENST00000367928.4
 VNN1
 vanin 1
chr10_+_101542462 0.21 ENST00000370449.4
ENST00000370434.1
 ABCC2
 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_-_190446759 0.21 ENST00000367462.3
 BRINP3
 bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr13_+_53602894 0.20 ENST00000219022.2
 OLFM4
 olfactomedin 4
chr9_+_90112590 0.20 ENST00000472284.1
 DAPK1
 death-associated protein kinase 1
chr9_+_90112767 0.20 ENST00000408954.3
 DAPK1
 death-associated protein kinase 1
chr9_-_99540328 0.19 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
 ZNF510
 zinc finger protein 510
chr2_+_102456277 0.19 ENST00000421882.1
 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
chr6_+_42749759 0.19 ENST00000314073.5
 GLTSCR1L
 GLTSCR1-like
chr16_-_66583701 0.19 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
 TK2
 thymidine kinase 2, mitochondrial
chr20_+_30697298 0.18 ENST00000398022.2
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr6_-_52705641 0.18 ENST00000370989.2
 GSTA5
 glutathione S-transferase alpha 5
chr19_+_21324827 0.18 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
 ZNF431
 zinc finger protein 431
chr20_+_56136136 0.17 ENST00000319441.4
ENST00000543666.1
 PCK1
 phosphoenolpyruvate carboxykinase 1 (soluble)
chr11_-_128894053 0.17 ENST00000392657.3
 ARHGAP32
 Rho GTPase activating protein 32
chr19_-_14945933 0.16 ENST00000322301.3
 OR7A5
 olfactory receptor, family 7, subfamily A, member 5
chr20_+_57594309 0.16 ENST00000217133.1
 TUBB1
 tubulin, beta 1 class VI
chr7_+_73868220 0.16 ENST00000455841.2
 GTF2IRD1
 GTF2I repeat domain containing 1
chr15_-_55489097 0.15 ENST00000260443.4
 RSL24D1
 ribosomal L24 domain containing 1
chr19_-_36304201 0.14 ENST00000301175.3
 PRODH2
 proline dehydrogenase (oxidase) 2
chr2_+_234826016 0.13 ENST00000324695.4
ENST00000433712.2
 TRPM8
 transient receptor potential cation channel, subfamily M, member 8
chrX_+_22050546 0.13 ENST00000379374.4
 PHEX
 phosphate regulating endopeptidase homolog, X-linked
chr1_-_212965104 0.13 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
 NSL1
 NSL1, MIS12 kinetochore complex component
chrX_-_106243451 0.13 ENST00000355610.4
ENST00000535534.1
 MORC4
 MORC family CW-type zinc finger 4
chrX_+_77166172 0.13 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr16_-_71842941 0.13 ENST00000423132.2
ENST00000433195.2
ENST00000569748.1
ENST00000570017.1
 AP1G1
 adaptor-related protein complex 1, gamma 1 subunit
chr6_+_26365443 0.13 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
 BTN3A2
 butyrophilin, subfamily 3, member A2
chr12_-_22063787 0.13 ENST00000544039.1
 ABCC9
 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_153919128 0.13 ENST00000361217.4
 DENND4B
 DENN/MADD domain containing 4B
chr17_-_72772462 0.12 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
 NAT9
 N-acetyltransferase 9 (GCN5-related, putative)
chr17_-_53800217 0.12 ENST00000424486.2
 TMEM100
 transmembrane protein 100
chr2_-_216946500 0.12 ENST00000265322.7
 PECR
 peroxisomal trans-2-enoyl-CoA reductase
chr15_+_84115868 0.12 ENST00000427482.2
 SH3GL3
 SH3-domain GRB2-like 3
chr2_-_27886460 0.12 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
 SUPT7L
 suppressor of Ty 7 (S. cerevisiae)-like
chr12_-_23737534 0.11 ENST00000396007.2
 SOX5
 SRY (sex determining region Y)-box 5
chr11_+_59824127 0.11 ENST00000278865.3
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_-_8977714 0.11 ENST00000319688.5
ENST00000489024.1
ENST00000256707.3
ENST00000427284.1
ENST00000418530.1
ENST00000473731.1
 KIDINS220
 kinase D-interacting substrate, 220kDa
chr12_+_104337515 0.11 ENST00000550595.1
 HSP90B1
 heat shock protein 90kDa beta (Grp94), member 1
chr18_-_53177984 0.11 ENST00000543082.1
 TCF4
 transcription factor 4
chr17_+_48823896 0.11 ENST00000511974.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr6_+_158733692 0.11 ENST00000367094.2
ENST00000367097.3
 TULP4
 tubby like protein 4
chr2_-_27886676 0.10 ENST00000337768.5
 SUPT7L
 suppressor of Ty 7 (S. cerevisiae)-like
chr2_-_21022818 0.10 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
 C2orf43
 chromosome 2 open reading frame 43
chr6_-_91296602 0.10 ENST00000369325.3
ENST00000369327.3
 MAP3K7
 mitogen-activated protein kinase kinase kinase 7
chr9_+_34652164 0.10 ENST00000441545.2
ENST00000553620.1
 IL11RA
 interleukin 11 receptor, alpha
chr3_+_44840679 0.10 ENST00000425755.1
 KIF15
 kinesin family member 15
chr19_+_49199209 0.09 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
 FUT2
 fucosyltransferase 2 (secretor status included)
chr6_-_91296737 0.09 ENST00000369332.3
ENST00000369329.3
 MAP3K7
 mitogen-activated protein kinase kinase kinase 7
chr7_-_101272576 0.09 ENST00000223167.4
 MYL10
 myosin, light chain 10, regulatory
chr16_-_71843047 0.09 ENST00000299980.4
ENST00000393512.3
 AP1G1
 adaptor-related protein complex 1, gamma 1 subunit
chr11_+_7618413 0.09 ENST00000528883.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr16_+_28565230 0.09 ENST00000317058.3
 CCDC101
 coiled-coil domain containing 101
chr13_-_36050819 0.08 ENST00000379919.4
 MAB21L1
 mab-21-like 1 (C. elegans)
chr2_+_202047596 0.08 ENST00000286186.6
ENST00000360132.3
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr6_+_26402465 0.08 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
 BTN3A1
 butyrophilin, subfamily 3, member A1
chr6_+_26087509 0.08 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
 HFE
 hemochromatosis
chr3_+_149191723 0.08 ENST00000305354.4
 TM4SF4
 transmembrane 4 L six family member 4
chr18_-_51750948 0.08 ENST00000583046.1
ENST00000398398.2
 MBD2
 methyl-CpG binding domain protein 2
chr7_-_140482926 0.08 ENST00000496384.2
 BRAF
 v-raf murine sarcoma viral oncogene homolog B
chr8_-_86253888 0.08 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
 CA1
 carbonic anhydrase I
chr11_+_59824060 0.08 ENST00000395032.2
ENST00000358152.2
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr2_-_191115229 0.07 ENST00000409820.2
ENST00000410045.1
 HIBCH
 3-hydroxyisobutyryl-CoA hydrolase
chr2_-_89385283 0.07 ENST00000390252.2
 IGKV3-15
 immunoglobulin kappa variable 3-15
chr4_+_5527117 0.07 ENST00000505296.1
 C4orf6
 chromosome 4 open reading frame 6
chr17_-_39093672 0.07 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
 KRT23
 keratin 23 (histone deacetylase inducible)
chr2_+_27886330 0.07 ENST00000326019.6
 SLC4A1AP
 solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr3_+_69812701 0.07 ENST00000472437.1
 MITF
 microphthalmia-associated transcription factor
chr12_-_25150373 0.06 ENST00000549828.1
 C12orf77
 chromosome 12 open reading frame 77
chr10_+_18549645 0.06 ENST00000396576.2
 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
chr12_-_10022735 0.06 ENST00000228438.2
 CLEC2B
 C-type lectin domain family 2, member B
chr18_+_46065393 0.06 ENST00000256413.3
 CTIF
 CBP80/20-dependent translation initiation factor
chr5_+_175288631 0.06 ENST00000509837.1
 CPLX2
 complexin 2
chr6_-_29527702 0.06 ENST00000377050.4
 UBD
 ubiquitin D
chr12_-_112123524 0.06 ENST00000327551.6
 BRAP
 BRCA1 associated protein
chr6_+_26087646 0.05 ENST00000309234.6
 HFE
 hemochromatosis
chr17_+_66511540 0.05 ENST00000588188.2
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_+_37455536 0.05 ENST00000381980.4
ENST00000508175.1
 C4orf19
 chromosome 4 open reading frame 19
chrX_-_100872911 0.05 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
 ARMCX6
 armadillo repeat containing, X-linked 6
chr5_-_20575959 0.05 ENST00000507958.1
 CDH18
 cadherin 18, type 2
chr5_-_125930929 0.05 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
 ALDH7A1
 aldehyde dehydrogenase 7 family, member A1
chr19_-_3772209 0.05 ENST00000555978.1
ENST00000555633.1
 RAX2
 retina and anterior neural fold homeobox 2
chr2_-_37068530 0.05 ENST00000593798.1
 AC007382.1
 Uncharacterized protein
chr2_+_202047843 0.05 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr19_-_19887185 0.05 ENST00000590092.1
ENST00000589910.1
ENST00000589508.1
ENST00000586645.1
ENST00000586816.1
ENST00000588223.1
ENST00000586885.1
 LINC00663
 long intergenic non-protein coding RNA 663
chr8_-_57123815 0.05 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
 PLAG1
 pleiomorphic adenoma gene 1
chr12_+_20963632 0.05 ENST00000540853.1
ENST00000261196.2
 SLCO1B3
 solute carrier organic anion transporter family, member 1B3
chrX_+_108779004 0.04 ENST00000218004.1
 NXT2
 nuclear transport factor 2-like export factor 2
chr17_+_48823975 0.04 ENST00000513969.1
ENST00000503728.1
 LUC7L3
 LUC7-like 3 (S. cerevisiae)
chr16_-_66584059 0.04 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
 TK2
 thymidine kinase 2, mitochondrial
chr7_-_64023441 0.04 ENST00000309683.6
 ZNF680
 zinc finger protein 680
chr3_+_141457105 0.04 ENST00000480908.1
ENST00000393000.3
 RNF7
 ring finger protein 7
chr8_+_121137333 0.04 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
 COL14A1
 collagen, type XIV, alpha 1
chr19_+_21264980 0.04 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
 ZNF714
 zinc finger protein 714
chr3_+_69812877 0.04 ENST00000457080.1
ENST00000328528.6
 MITF
 microphthalmia-associated transcription factor
chr9_-_21202204 0.04 ENST00000239347.3
 IFNA7
 interferon, alpha 7
chr1_-_233431458 0.04 ENST00000258229.9
ENST00000430153.1
 PCNXL2
 pecanex-like 2 (Drosophila)
chr1_+_10509971 0.04 ENST00000320498.4
 CORT
 cortistatin
chr3_+_141457030 0.04 ENST00000273480.3
 RNF7
 ring finger protein 7
chr4_+_71108300 0.04 ENST00000304954.3
 CSN3
 casein kappa
chr17_-_37607497 0.04 ENST00000394287.3
ENST00000300651.6
 MED1
 mediator complex subunit 1
chr2_+_68962014 0.04 ENST00000467265.1
 ARHGAP25
 Rho GTPase activating protein 25
chr14_+_102276209 0.03 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
 PPP2R5C
 protein phosphatase 2, regulatory subunit B', gamma
chrX_+_55744166 0.03 ENST00000374941.4
ENST00000414239.1
 RRAGB
 Ras-related GTP binding B
chr18_-_52989525 0.03 ENST00000457482.3
 TCF4
 transcription factor 4
chrX_+_55744228 0.03 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chr14_+_72052983 0.03 ENST00000358550.2
 SIPA1L1
 signal-induced proliferation-associated 1 like 1
chr12_-_118796910 0.03 ENST00000541186.1
ENST00000539872.1
 TAOK3
 TAO kinase 3
chr3_+_139063372 0.03 ENST00000478464.1
 MRPS22
 mitochondrial ribosomal protein S22
chr5_-_70316737 0.03 ENST00000194097.4
 NAIP
 NLR family, apoptosis inhibitory protein
chr6_-_112115074 0.03 ENST00000368667.2
 FYN
 FYN oncogene related to SRC, FGR, YES
chr1_+_78769549 0.03 ENST00000370758.1
 PTGFR
 prostaglandin F receptor (FP)
chr18_-_47018769 0.03 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
 RPL17
 ribosomal protein L17
chr3_-_9994021 0.03 ENST00000411976.2
ENST00000412055.1
 PRRT3
 proline-rich transmembrane protein 3
chrX_+_134975753 0.03 ENST00000535938.1
 SAGE1
 sarcoma antigen 1
chr5_+_81575281 0.03 ENST00000380167.4
 ATP6AP1L
 ATPase, H+ transporting, lysosomal accessory protein 1-like
chr5_-_149829244 0.02 ENST00000312037.5
 RPS14
 ribosomal protein S14
chrX_+_134975858 0.02 ENST00000537770.1
 SAGE1
 sarcoma antigen 1
chr2_-_136678123 0.02 ENST00000422708.1
 DARS
 aspartyl-tRNA synthetase
chr18_-_52989217 0.02 ENST00000570287.2
 TCF4
 transcription factor 4
chr15_+_75970672 0.02 ENST00000435356.1
 AC105020.1
 Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr10_-_115904361 0.02 ENST00000428953.1
ENST00000543782.1
 C10orf118
 chromosome 10 open reading frame 118
chr1_+_81771806 0.02 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr2_-_25391468 0.02 ENST00000395826.2
 POMC
 proopiomelanocortin
chr2_+_102953608 0.02 ENST00000311734.2
ENST00000409584.1
 IL1RL1
 interleukin 1 receptor-like 1
chr21_-_27423339 0.02 ENST00000415997.1
 APP
 amyloid beta (A4) precursor protein
chr9_-_21351377 0.02 ENST00000380210.1
 IFNA6
 interferon, alpha 6
chr3_+_186353756 0.02 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
 FETUB
 fetuin B
chr2_-_25391425 0.02 ENST00000264708.3
ENST00000449220.1
 POMC
 proopiomelanocortin
chr1_+_57320437 0.02 ENST00000361249.3
 C8A
 complement component 8, alpha polypeptide
chr4_+_113568207 0.02 ENST00000511529.1
 LARP7
 La ribonucleoprotein domain family, member 7
chr8_-_30670384 0.02 ENST00000221138.4
ENST00000518243.1
 PPP2CB
 protein phosphatase 2, catalytic subunit, beta isozyme
chr10_-_101989315 0.02 ENST00000370397.7
 CHUK
 conserved helix-loop-helix ubiquitous kinase
chr11_+_59856130 0.02 ENST00000278888.3
 MS4A2
 membrane-spanning 4-domains, subfamily A, member 2
chr7_-_44580861 0.02 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
 NPC1L1
 NPC1-like 1
chr2_-_74618964 0.02 ENST00000417090.1
ENST00000409868.1
 DCTN1
 dynactin 1
chr11_+_62037622 0.02 ENST00000227918.2
ENST00000525380.1
 SCGB2A2
 secretoglobin, family 2A, member 2
chr1_+_146714291 0.02 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
 CHD1L
 chromodomain helicase DNA binding protein 1-like
chr11_-_13011081 0.01 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
 LINC00958
 long intergenic non-protein coding RNA 958
chr4_-_100356551 0.01 ENST00000209665.4
 ADH7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.8 5.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.5 1.5 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.4 2.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.4 1.2 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.3 1.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 0.9 GO:0048539 bone marrow development(GO:0048539)
0.2 1.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.2 0.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 0.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.9 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 2.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 1.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.2 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) response to antineoplastic agent(GO:0097327)
0.1 1.0 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 2.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.6 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.0 GO:0072642 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0019770 IgG receptor activity(GO:0019770)
0.4 2.9 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.3 1.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.3 1.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 1.0 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2 1.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.2 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 1.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 5.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.1 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.8 GO:0043203 axon hillock(GO:0043203)
0.3 1.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.6 GO:0005607 laminin-2 complex(GO:0005607)
0.1 1.7 GO:0030478 actin cap(GO:0030478)
0.1 3.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.1 1.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 2.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)