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ENCODE cell lines, expression (Ernst 2011)

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Results for OTX1

Z-value: 0.49

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Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
OTX1
ENSG00000115507.5 OTX1

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_92351769 1.36 ENST00000212355.4
 TGFBR3
 transforming growth factor, beta receptor III
chr12_-_117537240 0.60 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
 TESC
 tescalcin
chr15_-_61521495 0.56 ENST00000335670.6
 RORA
 RAR-related orphan receptor A
chr2_-_160654745 0.53 ENST00000259053.4
ENST00000429078.2
 CD302
 CD302 molecule
chr10_+_114133773 0.48 ENST00000354655.4
 ACSL5
 acyl-CoA synthetase long-chain family member 5
chr1_-_247335269 0.46 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
 ZNF124
 zinc finger protein 124
chr16_+_33605231 0.43 ENST00000570121.2
 IGHV3OR16-12
 immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr12_-_54071181 0.42 ENST00000338662.5
 ATP5G2
 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr6_+_26251835 0.42 ENST00000356350.2
 HIST1H2BH
 histone cluster 1, H2bh
chr20_+_48884002 0.40 ENST00000425497.1
ENST00000445003.1
 RP11-290F20.3
 RP11-290F20.3
chr11_-_78052923 0.37 ENST00000340149.2
 GAB2
 GRB2-associated binding protein 2
chr1_+_28764653 0.35 ENST00000373836.3
 PHACTR4
 phosphatase and actin regulator 4
chr1_-_146696901 0.35 ENST00000369272.3
ENST00000441068.2
 FMO5
 flavin containing monooxygenase 5
chr21_-_43816052 0.34 ENST00000398405.1
 TMPRSS3
 transmembrane protease, serine 3
chr7_-_100239132 0.34 ENST00000223051.3
ENST00000431692.1
 TFR2
 transferrin receptor 2
chr7_+_120702819 0.34 ENST00000423795.1
 CPED1
 cadherin-like and PC-esterase domain containing 1
chr3_-_141747950 0.33 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr12_+_6603253 0.33 ENST00000382457.4
ENST00000545962.1
 NCAPD2
 non-SMC condensin I complex, subunit D2
chr15_+_58702742 0.30 ENST00000356113.6
ENST00000414170.3
 LIPC
 lipase, hepatic
chr11_+_128563652 0.30 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr6_+_26158343 0.29 ENST00000377777.4
ENST00000289316.2
 HIST1H2BD
 histone cluster 1, H2bd
chr19_+_17448348 0.29 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
 GTPBP3
 GTP binding protein 3 (mitochondrial)
chr6_+_106546808 0.29 ENST00000369089.3
 PRDM1
 PR domain containing 1, with ZNF domain
chr12_+_124997766 0.26 ENST00000543970.1
 RP11-83B20.1
 RP11-83B20.1
chr19_+_10381769 0.26 ENST00000423829.2
ENST00000588645.1
 ICAM1
 intercellular adhesion molecule 1
chr12_+_49740700 0.25 ENST00000549441.2
ENST00000395069.3
 DNAJC22
 DnaJ (Hsp40) homolog, subfamily C, member 22
chr6_+_96025341 0.25 ENST00000369293.1
ENST00000358812.4
 MANEA
 mannosidase, endo-alpha
chr4_-_122744998 0.24 ENST00000274026.5
 CCNA2
 cyclin A2
chr9_-_35665165 0.24 ENST00000343259.3
ENST00000378387.3
 ARHGEF39
 Rho guanine nucleotide exchange factor (GEF) 39
chr5_-_111091948 0.22 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr17_-_34329084 0.21 ENST00000354059.4
ENST00000536149.1
 CCL15
CCL14
 chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr22_-_36903101 0.21 ENST00000397224.4
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr15_+_42787452 0.20 ENST00000249647.3
 SNAP23
 synaptosomal-associated protein, 23kDa
chr19_-_41903161 0.20 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
 EXOSC5
 exosome component 5
chr2_-_74619152 0.20 ENST00000440727.1
ENST00000409240.1
 DCTN1
 dynactin 1
chr2_-_112642267 0.20 ENST00000341068.3
 ANAPC1
 anaphase promoting complex subunit 1
chr8_-_79717750 0.19 ENST00000263851.4
ENST00000379113.2
 IL7
 interleukin 7
chr1_-_216596738 0.19 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
 USH2A
 Usher syndrome 2A (autosomal recessive, mild)
chr19_-_47616992 0.18 ENST00000253048.5
 ZC3H4
 zinc finger CCCH-type containing 4
chr1_+_74701062 0.18 ENST00000326637.3
 TNNI3K
 TNNI3 interacting kinase
chr17_+_41158742 0.17 ENST00000415816.2
ENST00000438323.2
 IFI35
 interferon-induced protein 35
chrX_+_149861836 0.17 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
 MTMR1
 myotubularin related protein 1
chr12_-_71533055 0.16 ENST00000552128.1
 TSPAN8
 tetraspanin 8
chr3_+_58223228 0.16 ENST00000478253.1
ENST00000295962.4
 ABHD6
 abhydrolase domain containing 6
chr2_-_74618964 0.16 ENST00000417090.1
ENST00000409868.1
 DCTN1
 dynactin 1
chr1_+_174844645 0.16 ENST00000486220.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr2_+_122513109 0.15 ENST00000389682.3
ENST00000536142.1
 TSN
 translin
chr20_-_3140490 0.15 ENST00000449731.1
ENST00000380266.3
 UBOX5
FASTKD5
 U-box domain containing 5
FAST kinase domains 5
chr1_+_229440129 0.15 ENST00000366688.3
 SPHAR
 S-phase response (cyclin related)
chr14_-_106471723 0.15 ENST00000390595.2
 IGHV1-3
 immunoglobulin heavy variable 1-3
chr4_-_70626314 0.15 ENST00000510821.1
 SULT1B1
 sulfotransferase family, cytosolic, 1B, member 1
chr12_+_113354341 0.15 ENST00000553152.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr14_-_24911448 0.14 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
 SDR39U1
 short chain dehydrogenase/reductase family 39U, member 1
chr14_-_106539557 0.14 ENST00000390599.2
 IGHV1-8
 immunoglobulin heavy variable 1-8
chr9_+_125132803 0.13 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr16_-_21868978 0.13 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
 NPIPB4
 nuclear pore complex interacting protein family, member B4
chr1_-_204116078 0.13 ENST00000367198.2
ENST00000452983.1
 ETNK2
 ethanolamine kinase 2
chr11_+_113258495 0.13 ENST00000303941.3
 ANKK1
 ankyrin repeat and kinase domain containing 1
chr6_+_26204825 0.13 ENST00000360441.4
 HIST1H4E
 histone cluster 1, H4e
chr20_+_3052264 0.13 ENST00000217386.2
 OXT
 oxytocin/neurophysin I prepropeptide
chr15_+_43425672 0.12 ENST00000260403.2
 TMEM62
 transmembrane protein 62
chr19_+_41903709 0.12 ENST00000542943.1
ENST00000457836.2
 BCKDHA
 branched chain keto acid dehydrogenase E1, alpha polypeptide
chr6_-_32731243 0.12 ENST00000427449.1
ENST00000411527.1
 HLA-DQB2
 major histocompatibility complex, class II, DQ beta 2
chr12_-_14956396 0.12 ENST00000535328.1
ENST00000261167.2
 WBP11
 WW domain binding protein 11
chr6_-_41039567 0.12 ENST00000468811.1
 OARD1
 O-acyl-ADP-ribose deacylase 1
chr2_-_201936302 0.11 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
 FAM126B
 family with sequence similarity 126, member B
chr14_+_21458127 0.11 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
 METTL17
 methyltransferase like 17
chrX_-_100307043 0.11 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
 TRMT2B
 tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr5_+_59783941 0.11 ENST00000506884.1
ENST00000504876.2
 PART1
 prostate androgen-regulated transcript 1 (non-protein coding)
chr8_-_125577940 0.11 ENST00000519168.1
ENST00000395508.2
 MTSS1
 metastasis suppressor 1
chr8_-_33370607 0.11 ENST00000360742.5
ENST00000523305.1
 TTI2
 TELO2 interacting protein 2
chr16_-_8962200 0.11 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
 CARHSP1
 calcium regulated heat stable protein 1, 24kDa
chr16_+_69373323 0.11 ENST00000254940.5
 NIP7
 NIP7, nucleolar pre-rRNA processing protein
chr7_+_55980331 0.11 ENST00000429591.2
 ZNF713
 zinc finger protein 713
chr1_-_26372602 0.10 ENST00000374278.3
ENST00000374276.3
 SLC30A2
 solute carrier family 30 (zinc transporter), member 2
chr16_+_33204156 0.10 ENST00000398667.4
 TP53TG3C
 TP53 target 3C
chr14_-_107131560 0.10 ENST00000390632.2
 IGHV3-66
 immunoglobulin heavy variable 3-66
chr5_-_59783882 0.10 ENST00000505507.2
ENST00000502484.2
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr2_+_102721023 0.09 ENST00000409589.1
ENST00000409329.1
 IL1R1
 interleukin 1 receptor, type I
chrM_+_12331 0.09 ENST00000361567.2
 MT-ND5
 mitochondrially encoded NADH dehydrogenase 5
chr16_-_29874211 0.09 ENST00000563415.1
 CDIPT
 CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr1_+_150293973 0.09 ENST00000414970.2
ENST00000543398.1
 PRPF3
 pre-mRNA processing factor 3
chr16_-_29415350 0.09 ENST00000524087.1
 NPIPB11
 nuclear pore complex interacting protein family, member B11
chr1_-_36930012 0.08 ENST00000373116.5
 MRPS15
 mitochondrial ribosomal protein S15
chr2_+_201936458 0.08 ENST00000237889.4
 NDUFB3
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr1_+_150293921 0.07 ENST00000324862.6
 PRPF3
 pre-mRNA processing factor 3
chr16_-_21436459 0.07 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
 NPIPB3
 nuclear pore complex interacting protein family, member B3
chr8_-_110988070 0.07 ENST00000524391.1
 KCNV1
 potassium channel, subfamily V, member 1
chr14_-_102552659 0.07 ENST00000441629.2
 HSP90AA1
 heat shock protein 90kDa alpha (cytosolic), class A member 1
chr16_-_29875057 0.07 ENST00000219789.6
 CDIPT
 CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr1_+_45805342 0.07 ENST00000372090.5
 TOE1
 target of EGR1, member 1 (nuclear)
chr16_-_15950868 0.07 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
 MYH11
 myosin, heavy chain 11, smooth muscle
chrX_-_15333736 0.07 ENST00000380470.3
 ASB11
 ankyrin repeat and SOCS box containing 11
chr11_-_124767693 0.06 ENST00000533054.1
 ROBO4
 roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr3_+_195447738 0.06 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
 MUC20
 mucin 20, cell surface associated
chrX_+_100645812 0.06 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
 RPL36A
RPL36A-HNRNPH2
 ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr1_-_151300160 0.06 ENST00000368874.4
 PI4KB
 phosphatidylinositol 4-kinase, catalytic, beta
chr9_-_100935043 0.06 ENST00000343933.5
 CORO2A
 coronin, actin binding protein, 2A
chr1_-_160832642 0.06 ENST00000368034.4
 CD244
 CD244 molecule, natural killer cell receptor 2B4
chr1_+_17531614 0.06 ENST00000375471.4
 PADI1
 peptidyl arginine deiminase, type I
chr5_-_154230130 0.06 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
 FAXDC2
 fatty acid hydroxylase domain containing 2
chr1_-_153029980 0.06 ENST00000392653.2
 SPRR2A
 small proline-rich protein 2A
chr6_-_144416737 0.06 ENST00000367569.2
 SF3B5
 splicing factor 3b, subunit 5, 10kDa
chr11_-_67275542 0.05 ENST00000531506.1
 CDK2AP2
 cyclin-dependent kinase 2 associated protein 2
chr14_-_27066636 0.05 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
 NOVA1
 neuro-oncological ventral antigen 1
chr6_-_137539651 0.05 ENST00000543628.1
 IFNGR1
 interferon gamma receptor 1
chr16_-_29874462 0.05 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
 CDIPT
 CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr2_+_16080659 0.05 ENST00000281043.3
 MYCN
 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chrX_+_76709648 0.05 ENST00000439435.1
 FGF16
 fibroblast growth factor 16
chr5_+_59783540 0.05 ENST00000515734.2
 PART1
 prostate androgen-regulated transcript 1 (non-protein coding)
chr19_+_21265028 0.05 ENST00000291770.7
 ZNF714
 zinc finger protein 714
chr14_-_106967788 0.05 ENST00000390622.2
 IGHV1-46
 immunoglobulin heavy variable 1-46
chr3_+_11314099 0.04 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
 ATG7
 autophagy related 7
chr8_-_56986768 0.04 ENST00000523936.1
 RPS20
 ribosomal protein S20
chr15_-_34629922 0.04 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr19_-_3761673 0.04 ENST00000316757.3
 APBA3
 amyloid beta (A4) precursor protein-binding, family A, member 3
chr5_+_147443534 0.04 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
 SPINK5
 serine peptidase inhibitor, Kazal type 5
chr14_-_107170409 0.04 ENST00000390633.2
 IGHV1-69
 immunoglobulin heavy variable 1-69
chr15_-_43876702 0.04 ENST00000348806.6
 PPIP5K1
 diphosphoinositol pentakisphosphate kinase 1
chr11_-_62420757 0.04 ENST00000330574.2
 INTS5
 integrator complex subunit 5
chr19_-_16008880 0.04 ENST00000011989.7
ENST00000221700.6
 CYP4F2
 cytochrome P450, family 4, subfamily F, polypeptide 2
chr16_-_66583701 0.04 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
 TK2
 thymidine kinase 2, mitochondrial
chr11_-_65626797 0.04 ENST00000525451.2
 CFL1
 cofilin 1 (non-muscle)
chr5_+_177631497 0.04 ENST00000358344.3
 HNRNPAB
 heterogeneous nuclear ribonucleoprotein A/B
chr10_+_60028818 0.04 ENST00000333926.5
 CISD1
 CDGSH iron sulfur domain 1
chr17_+_43971643 0.04 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
 MAPT
 microtubule-associated protein tau
chr6_-_34393825 0.04 ENST00000605528.1
ENST00000326199.8
 RPS10-NUDT3
RPS10
 RPS10-NUDT3 readthrough
ribosomal protein S10
chr17_+_56769924 0.03 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
 RAD51C
 RAD51 paralog C
chr5_-_77072085 0.03 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
 TBCA
 tubulin folding cofactor A
chr19_+_35940486 0.03 ENST00000246549.2
 FFAR2
 free fatty acid receptor 2
chr15_-_89755034 0.03 ENST00000563254.1
 RLBP1
 retinaldehyde binding protein 1
chr4_+_100737954 0.03 ENST00000296414.7
ENST00000512369.1
 DAPP1
 dual adaptor of phosphotyrosine and 3-phosphoinositides
chr15_-_43877062 0.03 ENST00000381885.1
ENST00000396923.3
 PPIP5K1
 diphosphoinositol pentakisphosphate kinase 1
chr22_+_30163340 0.03 ENST00000330029.6
ENST00000401406.3
 UQCR10
 ubiquinol-cytochrome c reductase, complex III subunit X
chr3_-_58572760 0.03 ENST00000447756.2
 FAM107A
 family with sequence similarity 107, member A
chrX_-_49089771 0.03 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
 CACNA1F
 calcium channel, voltage-dependent, L type, alpha 1F subunit
chr8_+_22132847 0.03 ENST00000521356.1
 PIWIL2
 piwi-like RNA-mediated gene silencing 2
chr19_-_42916499 0.03 ENST00000601189.1
ENST00000599211.1
 LIPE
 lipase, hormone-sensitive
chr3_+_142315225 0.03 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1
 plastin 1
chr10_-_115423792 0.03 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
 NRAP
 nebulin-related anchoring protein
chr3_+_42544084 0.02 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
 VIPR1
 vasoactive intestinal peptide receptor 1
chr2_+_234580499 0.02 ENST00000354728.4
 UGT1A9
 UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_+_234580525 0.02 ENST00000609637.1
 UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A8
chr11_-_67210930 0.02 ENST00000453768.2
ENST00000545016.1
ENST00000341356.5
 CORO1B
 coronin, actin binding protein, 1B
chr7_-_120498357 0.02 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
 TSPAN12
 tetraspanin 12
chr2_+_232135245 0.02 ENST00000446447.1
 ARMC9
 armadillo repeat containing 9
chr6_+_35420091 0.02 ENST00000229769.2
 FANCE
 Fanconi anemia, complementation group E
chr14_-_89878369 0.01 ENST00000553840.1
ENST00000556916.1
 FOXN3
 forkhead box N3
chr3_+_121311966 0.01 ENST00000338040.4
 FBXO40
 F-box protein 40
chr8_+_101162812 0.01 ENST00000353107.3
ENST00000522439.1
 POLR2K
 polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr5_-_9712312 0.01 ENST00000506620.1
ENST00000514078.1
ENST00000606744.1
 TAS2R1
CTD-2143L24.1
 taste receptor, type 2, member 1
CTD-2143L24.1
chr14_-_27066960 0.01 ENST00000539517.2
 NOVA1
 neuro-oncological ventral antigen 1
chr9_-_100684845 0.01 ENST00000375119.3
 C9orf156
 chromosome 9 open reading frame 156
chr1_+_241695670 0.01 ENST00000366557.4
 KMO
 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr13_+_23755099 0.01 ENST00000537476.1
 SGCG
 sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_+_117910047 0.01 ENST00000356554.3
 MAN1A2
 mannosidase, alpha, class 1A, member 2
chr21_+_44073916 0.00 ENST00000349112.3
ENST00000398224.3
 PDE9A
 phosphodiesterase 9A
chr1_-_78444738 0.00 ENST00000436586.2
ENST00000370768.2
 FUBP1
 far upstream element (FUSE) binding protein 1
chr12_+_100594557 0.00 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
 ACTR6
 ARP6 actin-related protein 6 homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.0 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.6 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.3 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.6 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:1901859 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0002752 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.0 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0070341 fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling