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ENCODE cell lines, expression (Ernst 2011)

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Results for OTX2_CRX

Z-value: 0.47

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 OTX2
CRX
ENSG00000105392.11 CRX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CRXhg19_v2_chr19_+_48325097_48325211-0.371.6e-01Click!

Activity profile of OTX2_CRX motif

Sorted Z-values of OTX2_CRX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_175711133 1.51 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chr8_+_70378852 0.99 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
 SULF1
 sulfatase 1
chr5_-_88179302 0.98 ENST00000504921.2
 MEF2C
 myocyte enhancer factor 2C
chr5_-_88178964 0.92 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
 MEF2C
 myocyte enhancer factor 2C
chr1_+_114522049 0.89 ENST00000369551.1
ENST00000320334.4
 OLFML3
 olfactomedin-like 3
chr5_-_88179017 0.85 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
 MEF2C
 myocyte enhancer factor 2C
chr2_+_170366203 0.68 ENST00000284669.1
 KLHL41
 kelch-like family member 41
chr11_-_111783595 0.51 ENST00000528628.1
 CRYAB
 crystallin, alpha B
chr14_-_22005018 0.47 ENST00000546363.1
 SALL2
 spalt-like transcription factor 2
chr11_-_111794446 0.46 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr12_-_91576561 0.46 ENST00000547568.2
ENST00000552962.1
 DCN
 decorin
chr16_-_31076332 0.44 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
 ZNF668
 zinc finger protein 668
chrX_-_6146876 0.42 ENST00000381095.3
 NLGN4X
 neuroligin 4, X-linked
chr12_-_91576429 0.40 ENST00000552145.1
ENST00000546745.1
 DCN
 decorin
chr16_-_31076273 0.39 ENST00000426488.2
 ZNF668
 zinc finger protein 668
chr1_-_224033596 0.39 ENST00000391878.2
ENST00000343537.7
 TP53BP2
 tumor protein p53 binding protein, 2
chr12_-_91576750 0.39 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
 DCN
 decorin
chrX_-_124097620 0.38 ENST00000371130.3
ENST00000422452.2
 TENM1
 teneurin transmembrane protein 1
chr12_+_81101277 0.35 ENST00000228641.3
 MYF6
 myogenic factor 6 (herculin)
chr5_-_150138061 0.35 ENST00000521533.1
ENST00000424236.1
 DCTN4
 dynactin 4 (p62)
chr1_+_26644441 0.34 ENST00000374213.2
 CD52
 CD52 molecule
chr14_-_22005062 0.34 ENST00000317492.5
 SALL2
 spalt-like transcription factor 2
chr14_-_22005343 0.32 ENST00000327430.3
 SALL2
 spalt-like transcription factor 2
chrX_-_101771645 0.30 ENST00000289373.4
 TMSB15A
 thymosin beta 15a
chrX_+_135279179 0.29 ENST00000370676.3
 FHL1
 four and a half LIM domains 1
chr3_+_69915385 0.29 ENST00000314589.5
 MITF
 microphthalmia-associated transcription factor
chr2_-_175499294 0.27 ENST00000392547.2
 WIPF1
 WAS/WASL interacting protein family, member 1
chr12_-_90049828 0.26 ENST00000261173.2
ENST00000348959.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chrX_-_15619076 0.26 ENST00000252519.3
 ACE2
 angiotensin I converting enzyme 2
chr19_-_59066452 0.26 ENST00000312547.2
 CHMP2A
 charged multivesicular body protein 2A
chr12_-_90049878 0.24 ENST00000359142.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chrX_+_135278908 0.24 ENST00000539015.1
ENST00000370683.1
 FHL1
 four and a half LIM domains 1
chr18_-_21891460 0.24 ENST00000357041.4
 OSBPL1A
 oxysterol binding protein-like 1A
chr8_-_91095099 0.22 ENST00000265431.3
 CALB1
 calbindin 1, 28kDa
chr10_-_76868931 0.22 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
 DUSP13
 dual specificity phosphatase 13
chr21_-_34915147 0.20 ENST00000381831.3
ENST00000381839.3
 GART
 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr2_-_61765315 0.19 ENST00000406957.1
ENST00000401558.2
 XPO1
 exportin 1 (CRM1 homolog, yeast)
chr6_-_31697255 0.19 ENST00000436437.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr6_-_31697563 0.18 ENST00000375789.2
ENST00000416410.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr1_+_144989309 0.18 ENST00000596396.1
 AL590452.1
 Uncharacterized protein
chr3_-_50649192 0.18 ENST00000443053.2
ENST00000348721.3
 CISH
 cytokine inducible SH2-containing protein
chr19_-_10121144 0.17 ENST00000264828.3
 COL5A3
 collagen, type V, alpha 3
chr3_+_4535025 0.16 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
 ITPR1
 inositol 1,4,5-trisphosphate receptor, type 1
chr12_-_14849470 0.15 ENST00000261170.3
 GUCY2C
 guanylate cyclase 2C (heat stable enterotoxin receptor)
chrX_+_129473916 0.15 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr4_+_129730947 0.15 ENST00000452328.2
ENST00000504089.1
 PHF17
 jade family PHD finger 1
chr14_+_96722152 0.15 ENST00000216629.6
 BDKRB1
 bradykinin receptor B1
chr14_-_71107921 0.15 ENST00000553982.1
ENST00000500016.1
 CTD-2540L5.5
CTD-2540L5.6
 CTD-2540L5.5
CTD-2540L5.6
chr13_-_33780133 0.15 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr12_-_16758059 0.15 ENST00000261169.6
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr17_-_48207157 0.14 ENST00000330175.4
ENST00000503131.1
 SAMD14
 sterile alpha motif domain containing 14
chr1_+_244214577 0.14 ENST00000358704.4
 ZBTB18
 zinc finger and BTB domain containing 18
chr13_+_73632897 0.14 ENST00000377687.4
 KLF5
 Kruppel-like factor 5 (intestinal)
chr16_+_81272287 0.14 ENST00000425577.2
ENST00000564552.1
 BCMO1
 beta-carotene 15,15'-monooxygenase 1
chr14_-_101034407 0.14 ENST00000443071.2
ENST00000557378.1
 BEGAIN
 brain-enriched guanylate kinase-associated
chr18_+_32290218 0.13 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
 DTNA
 dystrobrevin, alpha
chr3_+_50649302 0.13 ENST00000446044.1
 MAPKAPK3
 mitogen-activated protein kinase-activated protein kinase 3
chr17_+_43318434 0.13 ENST00000587489.1
 FMNL1
 formin-like 1
chr12_-_16758304 0.13 ENST00000320122.6
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chrX_+_129473859 0.13 ENST00000424447.1
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr3_+_49058444 0.13 ENST00000326925.6
ENST00000395458.2
 NDUFAF3
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_-_42690312 0.13 ENST00000230381.5
 PRPH2
 peripherin 2 (retinal degeneration, slow)
chr2_-_119605253 0.13 ENST00000295206.6
 EN1
 engrailed homeobox 1
chr1_+_164528866 0.12 ENST00000420696.2
 PBX1
 pre-B-cell leukemia homeobox 1
chr13_-_36050819 0.12 ENST00000379919.4
 MAB21L1
 mab-21-like 1 (C. elegans)
chr9_-_130966497 0.12 ENST00000393608.1
ENST00000372948.3
 CIZ1
 CDKN1A interacting zinc finger protein 1
chr7_-_83824169 0.12 ENST00000265362.4
 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_+_52751010 0.12 ENST00000373985.1
 PRKG1
 protein kinase, cGMP-dependent, type I
chr9_-_95244781 0.11 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
 ASPN
 asporin
chr10_+_70661014 0.11 ENST00000373585.3
 DDX50
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr19_+_56166360 0.11 ENST00000308924.4
 U2AF2
 U2 small nuclear RNA auxiliary factor 2
chr1_-_173174681 0.11 ENST00000367718.1
 TNFSF4
 tumor necrosis factor (ligand) superfamily, member 4
chr4_+_129730779 0.11 ENST00000226319.6
 PHF17
 jade family PHD finger 1
chr10_+_95848824 0.11 ENST00000371385.3
ENST00000371375.1
 PLCE1
 phospholipase C, epsilon 1
chr19_+_2476116 0.11 ENST00000215631.4
ENST00000587345.1
 GADD45B
 growth arrest and DNA-damage-inducible, beta
chr11_-_118436707 0.10 ENST00000264020.2
ENST00000264021.3
 IFT46
 intraflagellar transport 46 homolog (Chlamydomonas)
chr11_-_62752162 0.10 ENST00000458333.2
ENST00000421062.2
 SLC22A6
 solute carrier family 22 (organic anion transporter), member 6
chr11_-_75017734 0.10 ENST00000532525.1
 ARRB1
 arrestin, beta 1
chr7_+_90338712 0.10 ENST00000265741.3
ENST00000406263.1
 CDK14
 cyclin-dependent kinase 14
chr7_+_80231466 0.10 ENST00000309881.7
ENST00000534394.1
 CD36
 CD36 molecule (thrombospondin receptor)
chr12_+_58138664 0.10 ENST00000257910.3
 TSPAN31
 tetraspanin 31
chr10_+_35464513 0.10 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
 CREM
 cAMP responsive element modulator
chr1_-_150208412 0.10 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_-_8680383 0.10 ENST00000299550.6
 TRIM66
 tripartite motif containing 66
chr2_-_225362533 0.09 ENST00000451538.1
 CUL3
 cullin 3
chr3_+_137483579 0.09 ENST00000306087.1
 SOX14
 SRY (sex determining region Y)-box 14
chr11_-_47198380 0.09 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
 ARFGAP2
 ADP-ribosylation factor GTPase activating protein 2
chr3_-_170626418 0.09 ENST00000474096.1
ENST00000295822.2
 EIF5A2
 eukaryotic translation initiation factor 5A2
chr1_-_241799232 0.09 ENST00000366553.1
 CHML
 choroideremia-like (Rab escort protein 2)
chr1_-_150208291 0.09 ENST00000533654.1
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_150208363 0.09 ENST00000436748.2
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_118628350 0.09 ENST00000537952.1
ENST00000537822.1
 TAOK3
 TAO kinase 3
chr12_+_58138800 0.09 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
 TSPAN31
 tetraspanin 31
chr10_+_52750930 0.08 ENST00000401604.2
 PRKG1
 protein kinase, cGMP-dependent, type I
chr17_-_46690839 0.08 ENST00000498634.2
 HOXB8
 homeobox B8
chr12_-_9913489 0.08 ENST00000228434.3
ENST00000536709.1
 CD69
 CD69 molecule
chr20_+_42984330 0.08 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
 HNF4A
 hepatocyte nuclear factor 4, alpha
chr19_-_51538148 0.08 ENST00000319590.4
ENST00000250351.4
 KLK12
 kallikrein-related peptidase 12
chr1_-_36615065 0.08 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
 TRAPPC3
 trafficking protein particle complex 3
chr22_+_41258250 0.08 ENST00000544094.1
 XPNPEP3
 X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr3_-_98241358 0.08 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
 CLDND1
 claudin domain containing 1
chr15_+_58430567 0.08 ENST00000536493.1
 AQP9
 aquaporin 9
chr15_+_58430368 0.08 ENST00000558772.1
ENST00000219919.4
 AQP9
 aquaporin 9
chr3_-_32612263 0.08 ENST00000432458.2
ENST00000424991.1
ENST00000273130.4
 DYNC1LI1
 dynein, cytoplasmic 1, light intermediate chain 1
chr10_-_126716459 0.08 ENST00000309035.6
 CTBP2
 C-terminal binding protein 2
chr1_-_150208498 0.07 ENST00000314136.8
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr21_+_34915337 0.07 ENST00000290239.6
ENST00000381692.2
ENST00000300278.4
ENST00000381679.4
 SON
 SON DNA binding protein
chr19_-_51538118 0.07 ENST00000529888.1
 KLK12
 kallikrein-related peptidase 12
chr9_+_82188077 0.07 ENST00000425506.1
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_64271363 0.07 ENST00000262150.2
 CDH19
 cadherin 19, type 2
chr6_-_111804905 0.07 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chrX_-_54384425 0.07 ENST00000375169.3
ENST00000354646.2
 WNK3
 WNK lysine deficient protein kinase 3
chr21_-_19775973 0.07 ENST00000284885.3
 TMPRSS15
 transmembrane protease, serine 15
chr19_+_40877583 0.07 ENST00000596470.1
 PLD3
 phospholipase D family, member 3
chrX_+_100645812 0.06 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
 RPL36A
RPL36A-HNRNPH2
 ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr6_+_31555045 0.06 ENST00000396101.3
ENST00000490742.1
 LST1
 leukocyte specific transcript 1
chr12_-_13248562 0.06 ENST00000457134.2
ENST00000537302.1
 GSG1
 germ cell associated 1
chr1_+_202431859 0.06 ENST00000391959.3
ENST00000367270.4
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr6_+_150920999 0.06 ENST00000367328.1
ENST00000367326.1
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chrX_-_64754611 0.05 ENST00000374807.5
ENST00000374811.3
ENST00000374804.5
ENST00000312391.8
 LAS1L
 LAS1-like (S. cerevisiae)
chr4_+_70894130 0.05 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
 HTN3
 histatin 3
chr2_-_214016314 0.05 ENST00000434687.1
ENST00000374319.4
 IKZF2
 IKAROS family zinc finger 2 (Helios)
chr8_-_87755878 0.05 ENST00000320005.5
 CNGB3
 cyclic nucleotide gated channel beta 3
chr19_+_39989580 0.05 ENST00000596614.1
ENST00000205143.4
 DLL3
 delta-like 3 (Drosophila)
chr22_-_30867973 0.04 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
 SEC14L3
 SEC14-like 3 (S. cerevisiae)
chr7_+_136553824 0.04 ENST00000320658.5
ENST00000453373.1
ENST00000397608.3
ENST00000402486.3
ENST00000401861.1
 CHRM2
 cholinergic receptor, muscarinic 2
chr12_-_13248732 0.04 ENST00000396302.3
 GSG1
 germ cell associated 1
chr3_+_49059038 0.04 ENST00000451378.2
 NDUFAF3
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_+_159409512 0.04 ENST00000423932.3
 OR10J1
 olfactory receptor, family 10, subfamily J, member 1
chr6_+_31554962 0.04 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
 LST1
 leukocyte specific transcript 1
chr11_-_118436606 0.04 ENST00000530872.1
 IFT46
 intraflagellar transport 46 homolog (Chlamydomonas)
chr5_+_140345820 0.04 ENST00000289269.5
 PCDHAC2
 protocadherin alpha subfamily C, 2
chr1_-_146082633 0.04 ENST00000605317.1
ENST00000604938.1
ENST00000339388.5
 NBPF11
 neuroblastoma breakpoint family, member 11
chr9_-_13279563 0.04 ENST00000541718.1
 MPDZ
 multiple PDZ domain protein
chr12_-_13248598 0.04 ENST00000337630.6
ENST00000545699.1
 GSG1
 germ cell associated 1
chr19_+_39989535 0.04 ENST00000356433.5
 DLL3
 delta-like 3 (Drosophila)
chr12_-_13248705 0.03 ENST00000396310.2
 GSG1
 germ cell associated 1
chr6_+_31554636 0.03 ENST00000433492.1
 LST1
 leukocyte specific transcript 1
chrX_+_153409678 0.03 ENST00000369951.4
 OPN1LW
 opsin 1 (cone pigments), long-wave-sensitive
chr22_+_25615489 0.03 ENST00000398215.2
 CRYBB2
 crystallin, beta B2
chrX_-_153363188 0.03 ENST00000303391.6
 MECP2
 methyl CpG binding protein 2 (Rett syndrome)
chr1_+_164529004 0.03 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
 PBX1
 pre-B-cell leukemia homeobox 1
chr13_-_31191642 0.03 ENST00000405805.1
 HMGB1
 high mobility group box 1
chr3_-_45837959 0.03 ENST00000353278.4
ENST00000456124.2
 SLC6A20
 solute carrier family 6 (proline IMINO transporter), member 20
chrX_+_69488174 0.03 ENST00000480877.2
ENST00000307959.8
 ARR3
 arrestin 3, retinal (X-arrestin)
chr1_+_209757051 0.03 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
 CAMK1G
 calcium/calmodulin-dependent protein kinase IG
chr10_+_118350522 0.03 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
 PNLIPRP1
 pancreatic lipase-related protein 1
chr5_+_150040403 0.03 ENST00000517768.1
ENST00000297130.4
 MYOZ3
 myozenin 3
chr5_-_11588907 0.03 ENST00000513598.1
ENST00000503622.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr15_-_35047166 0.02 ENST00000290374.4
 GJD2
 gap junction protein, delta 2, 36kDa
chr4_+_68424434 0.02 ENST00000265404.2
ENST00000396225.1
 STAP1
 signal transducing adaptor family member 1
chr3_-_50605150 0.02 ENST00000357203.3
 C3orf18
 chromosome 3 open reading frame 18
chr10_+_118350468 0.02 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
 PNLIPRP1
 pancreatic lipase-related protein 1
chr6_+_31554826 0.02 ENST00000376089.2
ENST00000396112.2
 LST1
 leukocyte specific transcript 1
chr7_+_136553370 0.02 ENST00000445907.2
 CHRM2
 cholinergic receptor, muscarinic 2
chr3_+_130650738 0.02 ENST00000504612.1
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr22_-_19137796 0.02 ENST00000086933.2
 GSC2
 goosecoid homeobox 2
chr3_-_45838011 0.02 ENST00000358525.4
ENST00000413781.1
 SLC6A20
 solute carrier family 6 (proline IMINO transporter), member 20
chr19_-_44123734 0.02 ENST00000598676.1
 ZNF428
 zinc finger protein 428
chr15_+_44092784 0.02 ENST00000458412.1
 HYPK
 huntingtin interacting protein K
chr10_-_104178857 0.02 ENST00000020673.5
 PSD
 pleckstrin and Sec7 domain containing
chr12_-_53171128 0.02 ENST00000332411.2
 KRT76
 keratin 76
chrX_+_100646190 0.02 ENST00000471855.1
 RPL36A
 ribosomal protein L36a
chr12_-_86650045 0.02 ENST00000604798.1
 MGAT4C
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr10_-_65028938 0.02 ENST00000402544.1
 JMJD1C
 jumonji domain containing 1C
chr10_+_102505468 0.02 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
 PAX2
 paired box 2
chr6_+_42141029 0.02 ENST00000372958.1
 GUCA1A
 guanylate cyclase activator 1A (retina)
chr14_+_88471468 0.02 ENST00000267549.3
 GPR65
 G protein-coupled receptor 65
chr9_+_12693336 0.02 ENST00000381137.2
ENST00000388918.5
 TYRP1
 tyrosinase-related protein 1
chr5_-_33984741 0.02 ENST00000382102.3
ENST00000509381.1
ENST00000342059.3
ENST00000345083.5
 SLC45A2
 solute carrier family 45, member 2
chr3_-_50605077 0.02 ENST00000426034.1
ENST00000441239.1
 C3orf18
 chromosome 3 open reading frame 18
chr9_-_20622478 0.02 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_+_162480918 0.02 ENST00000272716.5
ENST00000446997.1
 SLC4A10
 solute carrier family 4, sodium bicarbonate transporter, member 10
chr5_-_33984786 0.02 ENST00000296589.4
 SLC45A2
 solute carrier family 45, member 2
chr19_-_39881669 0.02 ENST00000221266.7
 PAF1
 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr7_-_100171270 0.02 ENST00000538735.1
 SAP25
 Sin3A-associated protein, 25kDa
chr12_-_86650077 0.02 ENST00000552808.2
ENST00000547225.1
 MGAT4C
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr16_-_21663919 0.02 ENST00000569602.1
 IGSF6
 immunoglobulin superfamily, member 6
chr15_+_33603147 0.01 ENST00000415757.3
ENST00000389232.4
 RYR3
 ryanodine receptor 3
chr19_-_51537982 0.01 ENST00000525263.1
 KLK12
 kallikrein-related peptidase 12
chr3_+_49057876 0.01 ENST00000326912.4
 NDUFAF3
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr3_-_137851220 0.01 ENST00000236709.3
 A4GNT
 alpha-1,4-N-acetylglucosaminyltransferase
chr5_-_149324306 0.01 ENST00000255266.5
 PDE6A
 phosphodiesterase 6A, cGMP-specific, rod, alpha
chr1_+_87380299 0.01 ENST00000370551.4
ENST00000370550.5
 HS2ST1
 heparan sulfate 2-O-sulfotransferase 1
chr11_+_72975559 0.01 ENST00000349767.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr10_+_104178946 0.01 ENST00000432590.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chr18_+_29769978 0.01 ENST00000269202.6
ENST00000581447.1
 MEP1B
 meprin A, beta
chr1_-_186430222 0.01 ENST00000391997.2
 PDC
 phosducin
chr1_+_20396649 0.01 ENST00000375108.3
 PLA2G5
 phospholipase A2, group V
chr12_-_67197760 0.01 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
 GRIP1
 glutamate receptor interacting protein 1
chrX_-_100129128 0.01 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
 NOX1
 NADPH oxidase 1
chr11_+_72975578 0.01 ENST00000393592.2
 P2RY6
 pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_+_159141397 0.01 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3
 cell adhesion molecule 3
chrX_+_69488155 0.01 ENST00000374495.3
 ARR3
 arrestin 3, retinal (X-arrestin)
chrX_-_49089771 0.01 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
 CACNA1F
 calcium channel, voltage-dependent, L type, alpha 1F subunit
chr14_-_58894332 0.01 ENST00000395159.2
 TIMM9
 translocase of inner mitochondrial membrane 9 homolog (yeast)
chr13_-_79980315 0.01 ENST00000438737.2
 RBM26
 RNA binding motif protein 26
chr3_-_9291063 0.01 ENST00000383836.3
 SRGAP3
 SLIT-ROBO Rho GTPase activating protein 3
chr12_-_56848426 0.01 ENST00000257979.4
 MIP
 major intrinsic protein of lens fiber
chr5_-_58882219 0.01 ENST00000505453.1
ENST00000360047.5
 PDE4D
 phosphodiesterase 4D, cAMP-specific

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.0 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 1.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.3 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.1 GO:0035690 cellular response to drug(GO:0035690)
0.1 0.6 GO:0003360 brainstem development(GO:0003360)
0.1 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.3 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.7 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.4 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:2000332 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.4 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway