Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for PAX3

Z-value: 0.78

Motif logo

logo of

Transcription factors associated with PAX3

Gene Symbol Gene ID Gene Info
PAX3
ENSG00000135903.14 PAX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX3hg19_v2_chr2_-_223163465_223163730-0.019.6e-01Click!

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_7060432 2.43 ENST00000318974.9
ENST00000456013.1
 PTPN6
 protein tyrosine phosphatase, non-receptor type 6
chr11_-_73694346 2.32 ENST00000310473.3
 UCP2
 uncoupling protein 2 (mitochondrial, proton carrier)
chr11_+_313503 2.14 ENST00000528780.1
ENST00000328221.5
 IFITM1
 interferon induced transmembrane protein 1
chr16_+_23847339 1.32 ENST00000303531.7
 PRKCB
 protein kinase C, beta
chr6_-_32908792 1.31 ENST00000418107.2
 HLA-DMB
 major histocompatibility complex, class II, DM beta
chr6_+_14117872 1.28 ENST00000379153.3
 CD83
 CD83 molecule
chr12_-_53594227 1.23 ENST00000550743.2
 ITGB7
 integrin, beta 7
chr7_+_99816859 1.16 ENST00000317271.2
 PVRIG
 poliovirus receptor related immunoglobulin domain containing
chr15_-_80263506 1.14 ENST00000335661.6
 BCL2A1
 BCL2-related protein A1
chr17_-_34417479 1.02 ENST00000225245.5
 CCL3
 chemokine (C-C motif) ligand 3
chr1_+_101185290 0.97 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
 VCAM1
 vascular cell adhesion molecule 1
chr11_-_615570 0.93 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
 IRF7
 interferon regulatory factor 7
chrX_-_53461288 0.87 ENST00000375298.4
ENST00000375304.5
 HSD17B10
 hydroxysteroid (17-beta) dehydrogenase 10
chrX_-_53461305 0.86 ENST00000168216.6
 HSD17B10
 hydroxysteroid (17-beta) dehydrogenase 10
chr6_-_109804412 0.79 ENST00000230122.3
 ZBTB24
 zinc finger and BTB domain containing 24
chr15_-_43622736 0.76 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
 LCMT2
 leucine carboxyl methyltransferase 2
chrX_-_15872914 0.75 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
 AP1S2
 adaptor-related protein complex 1, sigma 2 subunit
chr11_-_615942 0.74 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
 IRF7
 interferon regulatory factor 7
chr15_+_81591757 0.71 ENST00000558332.1
 IL16
 interleukin 16
chr5_+_49961727 0.70 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr9_-_35650900 0.69 ENST00000259608.3
 SIT1
 signaling threshold regulating transmembrane adaptor 1
chr6_-_32908765 0.51 ENST00000416244.2
 HLA-DMB
 major histocompatibility complex, class II, DM beta
chr2_+_152214098 0.50 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr7_-_148580563 0.46 ENST00000476773.1
 EZH2
 enhancer of zeste homolog 2 (Drosophila)
chr4_+_156680153 0.44 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
 GUCY1B3
 guanylate cyclase 1, soluble, beta 3
chr10_-_75226166 0.41 ENST00000544628.1
 PPP3CB
 protein phosphatase 3, catalytic subunit, beta isozyme
chr19_+_35168567 0.40 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
 ZNF302
 zinc finger protein 302
chr1_+_99729813 0.40 ENST00000457765.1
 LPPR4
 Lipid phosphate phosphatase-related protein type 4
chr7_+_116502605 0.39 ENST00000458284.2
ENST00000490693.1
 CAPZA2
 capping protein (actin filament) muscle Z-line, alpha 2
chr6_-_169654139 0.39 ENST00000366787.3
 THBS2
 thrombospondin 2
chr5_-_180688105 0.38 ENST00000327767.4
 TRIM52
 tripartite motif containing 52
chr6_+_127588020 0.35 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
 RNF146
 ring finger protein 146
chr4_+_156680143 0.34 ENST00000505154.1
 GUCY1B3
 guanylate cyclase 1, soluble, beta 3
chr19_+_35168633 0.34 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr8_+_107670064 0.32 ENST00000312046.6
 OXR1
 oxidation resistance 1
chr12_+_112563335 0.31 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
 TRAFD1
 TRAF-type zinc finger domain containing 1
chr3_-_119379427 0.31 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
 POPDC2
 popeye domain containing 2
chr1_-_205180664 0.30 ENST00000367161.3
ENST00000367162.3
ENST00000367160.4
 DSTYK
 dual serine/threonine and tyrosine protein kinase
chr12_+_112563303 0.30 ENST00000412615.2
 TRAFD1
 TRAF-type zinc finger domain containing 1
chr3_-_119379719 0.30 ENST00000493094.1
 POPDC2
 popeye domain containing 2
chr6_+_127587755 0.29 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
 RNF146
 ring finger protein 146
chr10_+_91087651 0.28 ENST00000371818.4
 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
chrX_+_30265256 0.27 ENST00000397548.2
 MAGEB1
 melanoma antigen family B, 1
chr11_-_104972158 0.26 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
 CASP1
CARD16
CARD17
 caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr3_+_183892635 0.26 ENST00000427072.1
ENST00000411763.2
ENST00000292807.5
ENST00000448139.1
ENST00000455925.1
 AP2M1
 adaptor-related protein complex 2, mu 1 subunit
chr5_+_178977546 0.25 ENST00000319449.4
ENST00000377001.2
 RUFY1
 RUN and FYVE domain containing 1
chr14_+_19553365 0.25 ENST00000409832.3
 POTEG
 POTE ankyrin domain family, member G
chr2_-_68479614 0.25 ENST00000234310.3
 PPP3R1
 protein phosphatase 3, regulatory subunit B, alpha
chr15_-_52861157 0.25 ENST00000564163.1
 ARPP19
 cAMP-regulated phosphoprotein, 19kDa
chr1_+_203444887 0.24 ENST00000343110.2
 PRELP
 proline/arginine-rich end leucine-rich repeat protein
chrX_+_102883620 0.22 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr9_+_100395891 0.22 ENST00000375147.3
 NCBP1
 nuclear cap binding protein subunit 1, 80kDa
chr19_-_41903161 0.21 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
 EXOSC5
 exosome component 5
chr2_-_44588893 0.20 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
 PREPL
 prolyl endopeptidase-like
chr5_+_70220768 0.20 ENST00000351205.4
ENST00000503079.2
ENST00000380707.4
ENST00000514951.1
ENST00000506163.1
 SMN1
 survival of motor neuron 1, telomeric
chr3_+_160117418 0.19 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
 SMC4
 structural maintenance of chromosomes 4
chr1_-_24151903 0.18 ENST00000436439.2
ENST00000374490.3
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr2_-_11810284 0.18 ENST00000306928.5
 NTSR2
 neurotensin receptor 2
chr10_-_104178857 0.18 ENST00000020673.5
 PSD
 pleckstrin and Sec7 domain containing
chr17_+_4855053 0.18 ENST00000518175.1
 ENO3
 enolase 3 (beta, muscle)
chr18_+_23806437 0.18 ENST00000578121.1
 TAF4B
 TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr10_+_118305435 0.18 ENST00000369221.2
 PNLIP
 pancreatic lipase
chr10_+_104178946 0.17 ENST00000432590.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chr12_-_57400227 0.17 ENST00000300101.2
 ZBTB39
 zinc finger and BTB domain containing 39
chr2_-_44588694 0.17 ENST00000409957.1
 PREPL
 prolyl endopeptidase-like
chr1_-_155214475 0.17 ENST00000428024.3
 GBA
 glucosidase, beta, acid
chr2_-_44588679 0.16 ENST00000409411.1
 PREPL
 prolyl endopeptidase-like
chr8_+_125463048 0.15 ENST00000328599.3
 TRMT12
 tRNA methyltransferase 12 homolog (S. cerevisiae)
chr5_+_69345350 0.15 ENST00000380741.4
ENST00000380743.4
ENST00000511812.1
ENST00000380742.4
 SMN2
 survival of motor neuron 2, centromeric
chr6_-_24721054 0.15 ENST00000378119.4
 C6orf62
 chromosome 6 open reading frame 62
chr16_+_27214802 0.14 ENST00000380948.2
ENST00000286096.4
 KDM8
 lysine (K)-specific demethylase 8
chr19_+_2841433 0.14 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
 ZNF555
 zinc finger protein 555
chr2_-_44588624 0.14 ENST00000438314.1
ENST00000409936.1
 PREPL
 prolyl endopeptidase-like
chr9_+_104161123 0.14 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
 ZNF189
 zinc finger protein 189
chr2_-_183106641 0.13 ENST00000346717.4
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr7_+_116502527 0.13 ENST00000361183.3
 CAPZA2
 capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_24151892 0.13 ENST00000235958.4
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr15_+_51973680 0.13 ENST00000542355.2
 SCG3
 secretogranin III
chr9_-_88897426 0.12 ENST00000375991.4
ENST00000326094.4
 ISCA1
 iron-sulfur cluster assembly 1
chr22_+_18593507 0.11 ENST00000330423.3
 TUBA8
 tubulin, alpha 8
chr3_+_160117087 0.11 ENST00000357388.3
 SMC4
 structural maintenance of chromosomes 4
chr1_-_205091115 0.11 ENST00000264515.6
ENST00000367164.1
 RBBP5
 retinoblastoma binding protein 5
chr22_-_44258360 0.11 ENST00000330884.4
ENST00000249130.5
 SULT4A1
 sulfotransferase family 4A, member 1
chr8_-_81083731 0.10 ENST00000379096.5
 TPD52
 tumor protein D52
chr15_+_51973550 0.10 ENST00000220478.3
 SCG3
 secretogranin III
chr21_-_37451680 0.10 ENST00000399201.1
 SETD4
 SET domain containing 4
chr8_-_101718991 0.09 ENST00000517990.1
 PABPC1
 poly(A) binding protein, cytoplasmic 1
chr11_+_66624527 0.09 ENST00000393952.3
 LRFN4
 leucine rich repeat and fibronectin type III domain containing 4
chr1_+_12524965 0.09 ENST00000471923.1
 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr19_-_41388657 0.09 ENST00000301146.4
ENST00000291764.3
 CYP2A7
 cytochrome P450, family 2, subfamily A, polypeptide 7
chr17_-_39538550 0.08 ENST00000394001.1
 KRT34
 keratin 34
chr6_+_89674246 0.08 ENST00000369474.1
 AL079342.1
 Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr14_-_24711806 0.08 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
 TINF2
 TERF1 (TRF1)-interacting nuclear factor 2
chr1_+_26496362 0.07 ENST00000374266.5
ENST00000270812.5
 ZNF593
 zinc finger protein 593
chr11_+_33563821 0.07 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
 KIAA1549L
 KIAA1549-like
chr6_+_35227449 0.07 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
 ZNF76
 zinc finger protein 76
chr9_-_91793675 0.07 ENST00000375835.4
ENST00000375830.1
 SHC3
 SHC (Src homology 2 domain containing) transforming protein 3
chr1_+_154244987 0.06 ENST00000328703.7
ENST00000457918.2
ENST00000483970.2
ENST00000435087.1
ENST00000532105.1
 HAX1
 HCLS1 associated protein X-1
chr12_+_10460549 0.05 ENST00000543420.1
ENST00000543777.1
 KLRD1
 killer cell lectin-like receptor subfamily D, member 1
chr22_+_20105259 0.05 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
 RANBP1
 RAN binding protein 1
chr1_-_155214436 0.04 ENST00000327247.5
 GBA
 glucosidase, beta, acid
chr1_-_52344471 0.04 ENST00000352171.7
ENST00000354831.7
 NRD1
 nardilysin (N-arginine dibasic convertase)
chr12_+_69080734 0.04 ENST00000378905.2
 NUP107
 nucleoporin 107kDa
chr13_+_96085847 0.03 ENST00000376873.3
 CLDN10
 claudin 10
chr19_-_54784353 0.03 ENST00000391746.1
 LILRB2
 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr20_-_17511962 0.03 ENST00000377873.3
 BFSP1
 beaded filament structural protein 1, filensin
chr2_-_219524193 0.03 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
 ZNF142
 zinc finger protein 142
chr22_+_39101728 0.03 ENST00000216044.5
ENST00000484657.1
 GTPBP1
 GTP binding protein 1
chr3_+_112709804 0.02 ENST00000383677.3
 GTPBP8
 GTP-binding protein 8 (putative)
chr3_+_112709755 0.02 ENST00000383678.2
 GTPBP8
 GTP-binding protein 8 (putative)
chr5_+_159343688 0.02 ENST00000306675.3
 ADRA1B
 adrenoceptor alpha 1B
chr15_+_99791567 0.02 ENST00000558879.1
ENST00000301981.3
ENST00000422500.2
ENST00000447360.2
ENST00000442993.2
 LRRC28
 leucine rich repeat containing 28
chr5_-_157079428 0.02 ENST00000265007.6
 SOX30
 SRY (sex determining region Y)-box 30
chr4_-_168155417 0.02 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
 SPOCK3
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr2_-_217724767 0.02 ENST00000236979.2
 TNP1
 transition protein 1 (during histone to protamine replacement)
chrX_+_70364667 0.02 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
 NLGN3
 neuroligin 3
chr20_-_23807358 0.01 ENST00000304725.2
 CST2
 cystatin SA
chr17_+_3118915 0.01 ENST00000304094.1
 OR1A1
 olfactory receptor, family 1, subfamily A, member 1
chrX_+_1734051 0.00 ENST00000381229.4
ENST00000381233.3
 ASMT
 acetylserotonin O-methyltransferase
chr10_-_102289611 0.00 ENST00000299166.4
ENST00000370320.4
ENST00000531258.1
ENST00000370322.1
ENST00000535773.1
 NDUFB8
SEC31B
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
SEC31 homolog B (S. cerevisiae)
chr19_+_55105085 0.00 ENST00000251372.3
ENST00000453777.1
 LILRA1
 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.6 2.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.6 1.7 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.4 1.3 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.3 1.7 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.3 1.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.3 0.8 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 2.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 1.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 1.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 0.5 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 2.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.2 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 1.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:1905216 positive regulation of RNA binding(GO:1905216)
0.0 1.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.7 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.5 GO:0030728 ovulation(GO:0030728)
0.0 0.7 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.3 1.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 1.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 2.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 0.3 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 3.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 4.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 2.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 1.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 2.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)