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ENCODE cell lines, expression (Ernst 2011)

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Results for PBX3

Z-value: 1.40

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Transcription factors associated with PBX3

Gene Symbol Gene ID Gene Info
PBX3
ENSG00000167081.12 PBX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX3hg19_v2_chr9_+_128509663_1285097330.107.0e-01Click!

Activity profile of PBX3 motif

Sorted Z-values of PBX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_+_89238149 6.58 ENST00000289746.2
 CDH15
 cadherin 15, type 1, M-cadherin (myotubule)
chr2_-_179672142 4.41 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
 TTN
 titin
chr11_-_2170786 2.78 ENST00000300632.5
 IGF2
 insulin-like growth factor 2 (somatomedin A)
chr2_-_45236540 2.34 ENST00000303077.6
 SIX2
 SIX homeobox 2
chr9_-_35689900 2.13 ENST00000378300.5
ENST00000329305.2
ENST00000360958.2
 TPM2
 tropomyosin 2 (beta)
chr17_-_1619535 2.08 ENST00000573075.1
ENST00000574306.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chrX_+_100805496 2.06 ENST00000372829.3
 ARMCX1
 armadillo repeat containing, X-linked 1
chr3_+_8775466 2.04 ENST00000343849.2
ENST00000397368.2
 CAV3
 caveolin 3
chr17_-_1619491 1.99 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chrX_-_100914781 1.90 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
 ARMCX2
 armadillo repeat containing, X-linked 2
chr17_+_48243352 1.82 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
 SGCA
 sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr3_+_30647994 1.81 ENST00000295754.5
 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
chr1_-_173176452 1.77 ENST00000281834.3
 TNFSF4
 tumor necrosis factor (ligand) superfamily, member 4
chr3_+_30648066 1.73 ENST00000359013.4
 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
chr3_-_52486841 1.73 ENST00000496590.1
 TNNC1
 troponin C type 1 (slow)
chr16_-_53537105 1.66 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
 AKTIP
 AKT interacting protein
chr6_-_169654139 1.58 ENST00000366787.3
 THBS2
 thrombospondin 2
chr9_+_75766652 1.56 ENST00000257497.6
 ANXA1
 annexin A1
chr1_+_100111479 1.42 ENST00000263174.4
 PALMD
 palmdelphin
chr10_-_76868931 1.42 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
 DUSP13
 dual specificity phosphatase 13
chr1_-_110283660 1.42 ENST00000361066.2
 GSTM3
 glutathione S-transferase mu 3 (brain)
chr1_-_110283138 1.40 ENST00000256594.3
 GSTM3
 glutathione S-transferase mu 3 (brain)
chr2_+_20646824 1.36 ENST00000272233.4
 RHOB
 ras homolog family member B
chrX_-_153637612 1.35 ENST00000369807.1
ENST00000369808.3
 DNASE1L1
 deoxyribonuclease I-like 1
chr21_-_39288743 1.21 ENST00000609713.1
 KCNJ6
 potassium inwardly-rectifying channel, subfamily J, member 6
chrX_+_102631248 1.20 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr10_+_102790980 1.18 ENST00000393459.1
ENST00000224807.5
 SFXN3
 sideroflexin 3
chr12_+_75874984 1.18 ENST00000550491.1
 GLIPR1
 GLI pathogenesis-related 1
chr13_+_73632897 1.17 ENST00000377687.4
 KLF5
 Kruppel-like factor 5 (intestinal)
chr12_+_75874460 1.16 ENST00000266659.3
 GLIPR1
 GLI pathogenesis-related 1
chr1_+_100111580 1.16 ENST00000605497.1
 PALMD
 palmdelphin
chr11_+_112832202 1.13 ENST00000534015.1
 NCAM1
 neural cell adhesion molecule 1
chr2_+_201171242 1.12 ENST00000360760.5
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr15_+_25068773 1.07 ENST00000400100.1
ENST00000400098.1
 SNRPN
 small nuclear ribonucleoprotein polypeptide N
chr16_+_56642041 1.07 ENST00000245185.5
 MT2A
 metallothionein 2A
chr5_-_179780312 1.06 ENST00000253778.8
 GFPT2
 glutamine-fructose-6-phosphate transaminase 2
chr3_+_35681081 1.03 ENST00000428373.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr2_+_201171064 0.99 ENST00000451764.2
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr2_+_201171372 0.99 ENST00000409140.3
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr3_+_197518100 0.98 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
 LRCH3
 leucine-rich repeats and calponin homology (CH) domain containing 3
chr19_+_16435625 0.96 ENST00000248071.5
ENST00000592003.1
 KLF2
 Kruppel-like factor 2
chr12_+_75874580 0.94 ENST00000456650.3
 GLIPR1
 GLI pathogenesis-related 1
chr19_-_45996465 0.94 ENST00000430715.2
 RTN2
 reticulon 2
chr2_+_201170770 0.92 ENST00000409988.3
ENST00000409385.1
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr9_+_34652164 0.90 ENST00000441545.2
ENST00000553620.1
 IL11RA
 interleukin 11 receptor, alpha
chr11_+_112832133 0.89 ENST00000524665.1
 NCAM1
 neural cell adhesion molecule 1
chr9_+_82186872 0.84 ENST00000376544.3
ENST00000376520.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_+_116327326 0.84 ENST00000342620.5
 RGS3
 regulator of G-protein signaling 3
chr12_-_91573249 0.82 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
 DCN
 decorin
chr12_-_91573132 0.75 ENST00000550563.1
ENST00000546370.1
 DCN
 decorin
chr10_+_114709999 0.73 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr19_-_23578220 0.73 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
 ZNF91
 zinc finger protein 91
chr5_-_140700322 0.72 ENST00000313368.5
 TAF7
 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
chr13_-_33780133 0.72 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr7_+_106809406 0.71 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
 HBP1
 HMG-box transcription factor 1
chr6_-_100912785 0.68 ENST00000369208.3
 SIM1
 single-minded family bHLH transcription factor 1
chr11_+_842928 0.68 ENST00000397408.1
 TSPAN4
 tetraspanin 4
chr19_-_49496557 0.68 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
 GYS1
 glycogen synthase 1 (muscle)
chr11_+_112832090 0.68 ENST00000533760.1
 NCAM1
 neural cell adhesion molecule 1
chr12_-_91573316 0.67 ENST00000393155.1
 DCN
 decorin
chr16_+_30210552 0.67 ENST00000338971.5
 SULT1A3
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr3_+_52489503 0.66 ENST00000345716.4
 NISCH
 nischarin
chr17_+_39975455 0.63 ENST00000455106.1
 FKBP10
 FK506 binding protein 10, 65 kDa
chr10_+_28966271 0.60 ENST00000375533.3
 BAMBI
 BMP and activin membrane-bound inhibitor
chr12_-_56123444 0.60 ENST00000546457.1
ENST00000549117.1
 CD63
 CD63 molecule
chr17_+_39975544 0.59 ENST00000544340.1
 FKBP10
 FK506 binding protein 10, 65 kDa
chr2_-_220435963 0.59 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
 OBSL1
 obscurin-like 1
chr19_-_12405689 0.58 ENST00000355684.5
 ZNF44
 zinc finger protein 44
chr7_-_30066233 0.58 ENST00000222803.5
 FKBP14
 FK506 binding protein 14, 22 kDa
chr19_-_14228541 0.57 ENST00000590853.1
ENST00000308677.4
 PRKACA
 protein kinase, cAMP-dependent, catalytic, alpha
chr9_+_82186682 0.57 ENST00000376552.2
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_-_35115836 0.56 ENST00000378566.1
ENST00000378554.2
ENST00000322813.5
 FAM214B
 family with sequence similarity 214, member B
chrX_-_134049262 0.55 ENST00000370783.3
 MOSPD1
 motile sperm domain containing 1
chr6_+_41021027 0.54 ENST00000244669.2
 APOBEC2
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr1_+_7831323 0.53 ENST00000054666.6
 VAMP3
 vesicle-associated membrane protein 3
chr14_-_82000140 0.52 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
 SEL1L
 sel-1 suppressor of lin-12-like (C. elegans)
chr7_+_150929550 0.50 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
 CHPF2
 chondroitin polymerizing factor 2
chr11_+_842808 0.50 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
 TSPAN4
 tetraspanin 4
chr20_+_35807512 0.48 ENST00000373622.5
 RPN2
 ribophorin II
chr19_+_21106081 0.47 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
 ZNF85
 zinc finger protein 85
chr10_-_101945771 0.47 ENST00000370408.2
ENST00000407654.3
 ERLIN1
 ER lipid raft associated 1
chr3_+_101498269 0.46 ENST00000491511.2
 NXPE3
 neurexophilin and PC-esterase domain family, member 3
chr5_-_150460914 0.46 ENST00000389378.2
 TNIP1
 TNFAIP3 interacting protein 1
chrX_+_102883887 0.45 ENST00000372625.3
ENST00000372624.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr4_+_6271558 0.45 ENST00000503569.1
ENST00000226760.1
 WFS1
 Wolfram syndrome 1 (wolframin)
chr17_+_46125707 0.44 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
 NFE2L1
 nuclear factor, erythroid 2-like 1
chr22_-_37172111 0.44 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
 IFT27
 intraflagellar transport 27 homolog (Chlamydomonas)
chr10_+_114710211 0.44 ENST00000349937.2
ENST00000369397.4
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr20_+_35807449 0.43 ENST00000237530.6
 RPN2
 ribophorin II
chr19_+_40877583 0.43 ENST00000596470.1
 PLD3
 phospholipase D family, member 3
chr22_-_37172191 0.41 ENST00000340630.5
 IFT27
 intraflagellar transport 27 homolog (Chlamydomonas)
chr4_+_90800656 0.41 ENST00000394980.1
 MMRN1
 multimerin 1
chr7_-_38370536 0.40 ENST00000390343.2
 TRGV8
 T cell receptor gamma variable 8
chr21_-_30257669 0.40 ENST00000303775.5
ENST00000351429.3
 N6AMT1
 N-6 adenine-specific DNA methyltransferase 1 (putative)
chr3_-_88108212 0.39 ENST00000482016.1
 CGGBP1
 CGG triplet repeat binding protein 1
chr19_-_50063907 0.38 ENST00000598296.1
 NOSIP
 nitric oxide synthase interacting protein
chr16_+_67927147 0.38 ENST00000291041.5
 PSKH1
 protein serine kinase H1
chr19_+_44556158 0.38 ENST00000434772.3
ENST00000585552.1
 ZNF223
 zinc finger protein 223
chr6_-_131321863 0.37 ENST00000528282.1
 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
chr16_-_30032610 0.37 ENST00000574405.1
 DOC2A
 double C2-like domains, alpha
chr10_+_99258625 0.37 ENST00000370664.3
 UBTD1
 ubiquitin domain containing 1
chr4_+_8594364 0.36 ENST00000360986.4
 CPZ
 carboxypeptidase Z
chr6_+_110299501 0.36 ENST00000414000.2
 GPR6
 G protein-coupled receptor 6
chr19_-_4867665 0.35 ENST00000592528.1
ENST00000589494.1
ENST00000585479.1
ENST00000221957.4
 PLIN3
 perilipin 3
chr6_-_32145861 0.35 ENST00000336984.6
 AGPAT1
 1-acylglycerol-3-phosphate O-acyltransferase 1
chr3_+_15643140 0.35 ENST00000449107.1
 BTD
 biotinidase
chr19_+_4969116 0.34 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
 KDM4B
 lysine (K)-specific demethylase 4B
chr7_+_116502605 0.34 ENST00000458284.2
ENST00000490693.1
 CAPZA2
 capping protein (actin filament) muscle Z-line, alpha 2
chr17_-_13505219 0.34 ENST00000284110.1
 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr7_+_99699179 0.33 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr3_+_184279566 0.33 ENST00000330394.2
 EPHB3
 EPH receptor B3
chr22_-_39151947 0.33 ENST00000216064.4
 SUN2
 Sad1 and UNC84 domain containing 2
chr19_+_38924316 0.33 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
 RYR1
 ryanodine receptor 1 (skeletal)
chr1_-_155211017 0.32 ENST00000536770.1
ENST00000368373.3
 GBA
 glucosidase, beta, acid
chr7_+_99699280 0.32 ENST00000421755.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr19_-_12251202 0.31 ENST00000334213.5
 ZNF20
 zinc finger protein 20
chr17_+_58755184 0.31 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
 BCAS3
 breast carcinoma amplified sequence 3
chr14_-_24584138 0.31 ENST00000558280.1
ENST00000561028.1
 NRL
 neural retina leucine zipper
chr14_-_91526922 0.30 ENST00000418736.2
ENST00000261991.3
 RPS6KA5
 ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr1_+_6845384 0.30 ENST00000303635.7
 CAMTA1
 calmodulin binding transcription activator 1
chr7_+_116502527 0.30 ENST00000361183.3
 CAPZA2
 capping protein (actin filament) muscle Z-line, alpha 2
chr5_+_149569520 0.30 ENST00000230671.2
ENST00000524041.1
 SLC6A7
 solute carrier family 6 (neurotransmitter transporter), member 7
chr3_+_15643245 0.30 ENST00000303498.5
ENST00000437172.1
 BTD
 biotinidase
chr12_+_51632508 0.30 ENST00000449723.3
 DAZAP2
 DAZ associated protein 2
chr3_-_88108192 0.29 ENST00000309534.6
 CGGBP1
 CGG triplet repeat binding protein 1
chr7_+_134331550 0.29 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
 BPGM
 2,3-bisphosphoglycerate mutase
chr22_-_39151995 0.29 ENST00000405018.1
ENST00000438058.1
 SUN2
 Sad1 and UNC84 domain containing 2
chr3_+_15643476 0.28 ENST00000436193.1
ENST00000383778.4
 BTD
 biotinidase
chr10_-_79789291 0.28 ENST00000372371.3
 POLR3A
 polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr4_+_124317940 0.27 ENST00000505319.1
ENST00000339241.1
 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr9_+_34989638 0.27 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
 DNAJB5
 DnaJ (Hsp40) homolog, subfamily B, member 5
chr9_-_128003606 0.27 ENST00000324460.6
 HSPA5
 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr8_-_41522779 0.27 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
 ANK1
 ankyrin 1, erythrocytic
chr1_-_155211065 0.27 ENST00000427500.3
 GBA
 glucosidase, beta, acid
chr16_+_31044413 0.27 ENST00000394998.1
 STX4
 syntaxin 4
chr5_-_37249397 0.27 ENST00000425232.2
ENST00000274258.7
 C5orf42
 chromosome 5 open reading frame 42
chr7_-_100183742 0.25 ENST00000310300.6
 LRCH4
 leucine-rich repeats and calponin homology (CH) domain containing 4
chr20_-_34330129 0.25 ENST00000397370.3
ENST00000528062.3
ENST00000407261.4
ENST00000374038.3
ENST00000361162.6
 RBM39
 RNA binding motif protein 39
chr6_-_11382478 0.25 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
chr10_-_44144152 0.24 ENST00000395797.1
 ZNF32
 zinc finger protein 32
chr19_+_2841433 0.24 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
 ZNF555
 zinc finger protein 555
chr19_+_12035913 0.24 ENST00000591944.1
 ZNF763
 Uncharacterized protein; Zinc finger protein 763
chr16_+_85061367 0.24 ENST00000538274.1
ENST00000258180.3
 KIAA0513
 KIAA0513
chr3_-_49823941 0.24 ENST00000321599.4
ENST00000395238.1
ENST00000468463.1
ENST00000460540.1
 IP6K1
 inositol hexakisphosphate kinase 1
chr17_+_61699766 0.24 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
 MAP3K3
 mitogen-activated protein kinase kinase kinase 3
chr12_-_16761007 0.24 ENST00000354662.1
ENST00000441439.2
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr19_-_45873642 0.23 ENST00000485403.2
ENST00000586856.1
ENST00000586131.1
ENST00000391940.4
ENST00000221481.6
ENST00000391944.3
ENST00000391945.4
 ERCC2
 excision repair cross-complementing rodent repair deficiency, complementation group 2
chr19_+_55591743 0.23 ENST00000588359.1
ENST00000245618.5
 EPS8L1
 EPS8-like 1
chr11_-_86383157 0.23 ENST00000393324.3
 ME3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
chr19_+_21688366 0.23 ENST00000358491.4
ENST00000597078.1
 ZNF429
 zinc finger protein 429
chr22_-_36784035 0.23 ENST00000216181.5
 MYH9
 myosin, heavy chain 9, non-muscle
chr2_-_71062938 0.22 ENST00000410009.3
 CD207
 CD207 molecule, langerin
chr17_-_17875688 0.22 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
 TOM1L2
 target of myb1-like 2 (chicken)
chr8_+_26240414 0.22 ENST00000380629.2
 BNIP3L
 BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr17_+_17876127 0.22 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
 LRRC48
 leucine rich repeat containing 48
chr2_-_220094031 0.22 ENST00000443140.1
ENST00000432520.1
ENST00000409618.1
 ATG9A
 autophagy related 9A
chr1_-_28969517 0.22 ENST00000263974.4
ENST00000373824.4
 TAF12
 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr3_+_48481658 0.21 ENST00000438607.2
 TMA7
 translation machinery associated 7 homolog (S. cerevisiae)
chr17_-_8066250 0.21 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
 VAMP2
RP11-599B13.6
 vesicle-associated membrane protein 2 (synaptobrevin 2)
Uncharacterized protein
chr14_+_23938891 0.21 ENST00000408901.3
ENST00000397154.3
ENST00000555128.1
 NGDN
 neuroguidin, EIF4E binding protein
chr11_-_86383370 0.21 ENST00000526834.1
ENST00000359636.2
 ME3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
chr10_-_44144292 0.21 ENST00000374433.2
 ZNF32
 zinc finger protein 32
chr16_-_79634595 0.21 ENST00000326043.4
ENST00000393350.1
 MAF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr7_+_72742162 0.21 ENST00000431982.2
 FKBP6
 FK506 binding protein 6, 36kDa
chr14_+_24583836 0.21 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
 DCAF11
 DDB1 and CUL4 associated factor 11
chr21_+_44394620 0.21 ENST00000291547.5
 PKNOX1
 PBX/knotted 1 homeobox 1
chr13_+_20532848 0.20 ENST00000382874.2
 ZMYM2
 zinc finger, MYM-type 2
chr12_-_56615693 0.20 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
 RNF41
 ring finger protein 41
chr12_+_51632638 0.20 ENST00000549732.2
 DAZAP2
 DAZ associated protein 2
chr7_+_72742178 0.20 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
 FKBP6
 FK506 binding protein 6, 36kDa
chr16_+_1756162 0.20 ENST00000250894.4
ENST00000356010.5
 MAPK8IP3
 mitogen-activated protein kinase 8 interacting protein 3
chr7_+_64838712 0.19 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
 ZNF92
 zinc finger protein 92
chr19_-_23941639 0.19 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
 ZNF681
 zinc finger protein 681
chr20_-_17539456 0.19 ENST00000544874.1
ENST00000377868.2
 BFSP1
 beaded filament structural protein 1, filensin
chr13_+_20532900 0.19 ENST00000382871.2
 ZMYM2
 zinc finger, MYM-type 2
chr7_+_149571045 0.18 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
 ATP6V0E2
 ATPase, H+ transporting V0 subunit e2
chr19_+_41284121 0.18 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
 RAB4B
 RAB4B, member RAS oncogene family
chr2_-_220436248 0.18 ENST00000265318.4
 OBSL1
 obscurin-like 1
chr14_+_76127529 0.18 ENST00000556977.1
ENST00000557636.1
ENST00000286650.5
ENST00000298832.9
 TTLL5
 tubulin tyrosine ligase-like family, member 5
chr11_-_73720122 0.18 ENST00000426995.2
 UCP3
 uncoupling protein 3 (mitochondrial, proton carrier)
chrX_+_153059608 0.17 ENST00000370087.1
 SSR4
 signal sequence receptor, delta
chr14_-_73925225 0.17 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
 NUMB
 numb homolog (Drosophila)
chr17_-_40306934 0.17 ENST00000592574.1
ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
 CTD-2132N18.3
RAB5C
 Uncharacterized protein
RAB5C, member RAS oncogene family
chr12_+_123717458 0.17 ENST00000253233.1
 C12orf65
 chromosome 12 open reading frame 65
chr8_-_41522719 0.17 ENST00000335651.6
 ANK1
 ankyrin 1, erythrocytic
chr19_-_57988871 0.17 ENST00000596831.1
ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
 AC004076.9
ZNF772
 Uncharacterized protein
zinc finger protein 772
chr8_+_31496809 0.16 ENST00000518104.1
ENST00000519301.1
 NRG1
 neuregulin 1
chr7_+_55433131 0.16 ENST00000254770.2
 LANCL2
 LanC lantibiotic synthetase component C-like 2 (bacterial)
chr17_-_8534031 0.16 ENST00000411957.1
ENST00000396239.1
ENST00000379980.4
 MYH10
 myosin, heavy chain 10, non-muscle
chr7_-_38407770 0.16 ENST00000390348.2
 TRGV1
 T cell receptor gamma variable 1 (non-functional)
chr7_-_75368248 0.16 ENST00000434438.2
ENST00000336926.6
 HIP1
 huntingtin interacting protein 1
chr16_-_89556942 0.16 ENST00000301030.4
 ANKRD11
 ankyrin repeat domain 11
chr3_-_187454281 0.16 ENST00000232014.4
 BCL6
 B-cell CLL/lymphoma 6
chr1_+_205197304 0.16 ENST00000358024.3
 TMCC2
 transmembrane and coiled-coil domain family 2
chr22_-_39151463 0.16 ENST00000405510.1
ENST00000433561.1
 SUN2
 Sad1 and UNC84 domain containing 2
chr16_+_28889703 0.15 ENST00000357084.3
 ATP2A1
 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr9_-_33264557 0.15 ENST00000473781.1
ENST00000488499.1
 BAG1
 BCL2-associated athanogene
chr2_-_220094294 0.15 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
 ATG9A
 autophagy related 9A
chr17_+_7482785 0.15 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
 CD68
 CD68 molecule
chr19_+_21265028 0.15 ENST00000291770.7
 ZNF714
 zinc finger protein 714

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.4 GO:0035995 detection of muscle stretch(GO:0035995)
1.2 3.5 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.8 2.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.6 1.8 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.6 2.8 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.5 1.6 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.4 1.7 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.4 1.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 1.0 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.3 2.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 1.4 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 1.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 2.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.8 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 0.5 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.6 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0097501 stress response to metal ion(GO:0097501)
0.1 1.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.8 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.7 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.3 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.2 GO:0021592 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 1.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 1.4 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.2 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 0.7 GO:0015846 polyamine transport(GO:0015846)
0.1 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.6 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.1 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 6.5 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.1 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.9 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.6 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 1.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.7 GO:0048243 norepinephrine secretion(GO:0048243)
0.0 0.7 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.6 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 2.1 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:1902617 response to fluoride(GO:1902617)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 1.2 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0035912 dorsal aorta morphogenesis(GO:0035912) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 2.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.9 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.2 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 2.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.0 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.0 1.1 GO:0046323 glucose import(GO:0046323)
0.0 0.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086) cell cycle G2/M phase transition(GO:0044839)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.6 GO:0007566 embryo implantation(GO:0007566)
0.0 0.3 GO:0006986 response to unfolded protein(GO:0006986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0070695 FHF complex(GO:0070695)
0.4 3.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 1.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 1.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.3 2.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 2.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.3 GO:0014802 terminal cisterna(GO:0014802)
0.2 0.8 GO:1990393 3M complex(GO:1990393)
0.1 4.3 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 2.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 8.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.1 GO:0005687 U4 snRNP(GO:0005687)
0.1 4.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 4.2 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0031094 platelet dense tubular network(GO:0031094) platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 2.0 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.4 4.4 GO:0031433 telethonin binding(GO:0031433)
0.3 2.0 GO:0071253 connexin binding(GO:0071253)
0.3 1.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 0.9 GO:0047708 biotinidase activity(GO:0047708)
0.2 0.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 0.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.7 GO:0031013 troponin I binding(GO:0031013)
0.2 2.6 GO:0043295 glutathione binding(GO:0043295)
0.1 0.6 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.7 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.1 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1 2.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 1.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.1 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0 1.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 1.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.4 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 1.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 9.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 3.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 3.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 2.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 1.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.6 PID FGF PATHWAY FGF signaling pathway
0.0 1.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.