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ENCODE cell lines, expression (Ernst 2011)

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Results for PKNOX1_TGIF2

Z-value: 1.50

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
ENSG00000160199.10 PKNOX1
ENSG00000118707.5 TGIF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2hg19_v2_chr20_+_35201993_35202050,
hg19_v2_chr20_+_35201857_35201891
0.759.0e-04Click!
PKNOX1hg19_v2_chr21_+_44394620_44394737-0.495.6e-02Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_52828805 5.56 ENST00000416872.2
ENST00000449956.2
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chr1_+_207262540 3.96 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr1_+_207262881 3.93 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr1_+_207262170 3.59 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr4_+_166300084 3.52 ENST00000402744.4
CPE
carboxypeptidase E
chr1_+_207262578 3.52 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr1_+_207262627 3.49 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr2_+_118846008 3.42 ENST00000245787.4
INSIG2
insulin induced gene 2
chr6_+_138188551 3.07 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_-_94856987 2.89 ENST00000449399.3
ENST00000404814.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_94857004 2.79 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_94856951 2.79 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_-_64225508 2.43 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr21_-_34186006 2.28 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr9_-_33447584 2.15 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr10_-_118764862 2.08 ENST00000260777.10
KIAA1598
KIAA1598
chr21_-_34185944 2.08 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr15_-_61521495 2.03 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr21_-_34185989 1.96 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr6_+_111195973 1.95 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr7_+_29234028 1.81 ENST00000222792.6
CHN2
chimerin 2
chr6_+_26124373 1.81 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr16_-_30457048 1.79 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr16_+_2588012 1.75 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr8_-_17752912 1.71 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chr6_-_32140886 1.68 ENST00000395496.1
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr7_+_29234101 1.61 ENST00000435288.2
CHN2
chimerin 2
chr9_-_111696340 1.60 ENST00000374647.5
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr16_+_30212378 1.58 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_-_148580563 1.53 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr10_-_73848531 1.50 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr22_+_17082732 1.50 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr11_-_107729887 1.47 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr7_-_156803329 1.44 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr13_-_41837620 1.32 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1
mitochondrial translational release factor 1
chr10_-_11574274 1.30 ENST00000277575.5
USP6NL
USP6 N-terminal like
chr1_-_63988846 1.29 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr1_+_2036149 1.27 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
PRKCZ
protein kinase C, zeta
chr3_-_142166904 1.25 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr1_-_54872059 1.22 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr3_-_49726486 1.22 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr3_+_52719936 1.17 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr10_-_73848764 1.15 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_-_175443943 1.15 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_+_22778337 1.12 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr1_+_154966058 1.09 ENST00000392487.1
LENEP
lens epithelial protein
chr16_-_3030407 1.06 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr19_-_12512062 1.05 ENST00000595766.1
ENST00000430385.3
ZNF799
zinc finger protein 799
chr14_-_21493123 1.05 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr2_+_85804614 1.04 ENST00000263864.5
ENST00000409760.1
VAMP8
vesicle-associated membrane protein 8
chr5_-_169725231 1.03 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr13_+_33160553 1.02 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr6_+_31865552 1.02 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr7_+_94536898 1.00 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr14_-_94759408 0.99 ENST00000554723.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr2_+_242127924 0.99 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
ANO7
anoctamin 7
chr2_+_233925064 0.98 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr10_-_118765081 0.98 ENST00000392903.2
ENST00000355371.4
KIAA1598
KIAA1598
chr18_-_52626622 0.98 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr14_-_94759361 0.96 ENST00000393096.1
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_-_39322299 0.96 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
ECH1
enoyl CoA hydratase 1, peroxisomal
chr2_+_113885138 0.94 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr1_-_247335269 0.92 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr17_+_38296576 0.89 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr10_+_28966271 0.88 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr8_+_11666649 0.88 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr12_-_31479045 0.86 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr1_+_28844648 0.86 ENST00000373832.1
ENST00000373831.3
RCC1
regulator of chromosome condensation 1
chr13_-_46716969 0.85 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_105416039 0.83 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr19_-_12551849 0.82 ENST00000595562.1
ENST00000301547.5
CTD-3105H18.16
ZNF443
Uncharacterized protein
zinc finger protein 443
chr3_-_3221358 0.79 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr10_+_28822636 0.78 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr8_-_141774467 0.75 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr5_-_58882219 0.75 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_-_37392086 0.74 ENST00000561208.1
MEIS2
Meis homeobox 2
chr4_+_3076388 0.72 ENST00000355072.5
HTT
huntingtin
chr2_+_62900986 0.71 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
EHBP1
EH domain binding protein 1
chr10_+_114710516 0.71 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr19_+_2867325 0.70 ENST00000307635.2
ENST00000586426.1
ZNF556
zinc finger protein 556
chr16_+_2587998 0.70 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr15_+_68346501 0.68 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr1_+_74701062 0.68 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr19_-_39322497 0.66 ENST00000221418.4
ECH1
enoyl CoA hydratase 1, peroxisomal
chr14_-_21492113 0.66 ENST00000554094.1
NDRG2
NDRG family member 2
chr8_-_99837856 0.65 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr19_+_49496705 0.65 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr9_-_132805430 0.65 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chrX_+_135730373 0.64 ENST00000370628.2
CD40LG
CD40 ligand
chr10_+_51565188 0.64 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr21_-_34143971 0.62 ENST00000290178.4
PAXBP1
PAX3 and PAX7 binding protein 1
chrX_+_135730297 0.62 ENST00000370629.2
CD40LG
CD40 ligand
chr2_-_24149977 0.61 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr7_+_29234375 0.60 ENST00000409350.1
ENST00000495789.2
ENST00000539389.1
CHN2
chimerin 2
chr12_+_72148614 0.60 ENST00000261263.3
RAB21
RAB21, member RAS oncogene family
chr12_-_91451758 0.59 ENST00000266719.3
KERA
keratocan
chr2_+_128848881 0.56 ENST00000259253.6
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr9_-_124989804 0.56 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr1_+_205473720 0.56 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr14_-_21492251 0.55 ENST00000554398.1
NDRG2
NDRG family member 2
chr2_-_183106641 0.55 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr3_+_111260954 0.55 ENST00000283285.5
CD96
CD96 molecule
chr3_+_185080908 0.54 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr9_+_133454943 0.54 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr1_-_225615599 0.53 ENST00000421383.1
ENST00000272163.4
LBR
lamin B receptor
chr4_-_46391805 0.53 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr1_-_53163992 0.53 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr3_-_52569023 0.52 ENST00000307076.4
NT5DC2
5'-nucleotidase domain containing 2
chr19_-_10764509 0.51 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr2_+_128848740 0.51 ENST00000375990.3
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr4_-_83483395 0.49 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr19_-_45663408 0.49 ENST00000317951.4
NKPD1
NTPase, KAP family P-loop domain containing 1
chr19_-_13044494 0.49 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr3_+_63897605 0.48 ENST00000487717.1
ATXN7
ataxin 7
chr1_-_51425902 0.48 ENST00000396153.2
FAF1
Fas (TNFRSF6) associated factor 1
chr20_-_33872518 0.47 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr7_+_95115210 0.47 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr12_-_91398796 0.47 ENST00000261172.3
ENST00000551767.1
EPYC
epiphycan
chr2_+_99953816 0.46 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr17_+_13972807 0.46 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
COX10
cytochrome c oxidase assembly homolog 10 (yeast)
chr6_-_131949200 0.44 ENST00000539158.1
ENST00000368058.1
MED23
mediator complex subunit 23
chr7_-_104909435 0.44 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr18_+_3449821 0.43 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr6_-_35656685 0.43 ENST00000539068.1
ENST00000540787.1
FKBP5
FK506 binding protein 5
chr19_+_49496782 0.43 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr11_+_129245796 0.41 ENST00000281437.4
BARX2
BARX homeobox 2
chr20_-_33872548 0.40 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr21_-_34144157 0.40 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chr21_-_43735446 0.38 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr6_-_86099898 0.38 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr17_-_39661849 0.37 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr19_-_51538148 0.37 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr2_-_61765315 0.36 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr8_-_17555164 0.35 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr5_-_132073111 0.34 ENST00000403231.1
KIF3A
kinesin family member 3A
chr14_-_21994525 0.34 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr19_-_51538118 0.34 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr12_+_69201923 0.34 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr16_+_16484691 0.34 ENST00000344087.4
NPIPA7
nuclear pore complex interacting protein family, member A7
chr17_+_76374714 0.33 ENST00000262764.6
ENST00000589689.1
ENST00000329897.7
ENST00000592043.1
ENST00000587356.1
PGS1
phosphatidylglycerophosphate synthase 1
chr19_-_12267524 0.32 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
ZNF625
zinc finger protein 625
chr16_+_2587965 0.32 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr2_-_152589670 0.32 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr6_+_41021027 0.31 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr6_-_131949305 0.30 ENST00000368053.4
ENST00000354577.4
ENST00000403834.3
ENST00000540546.1
ENST00000368068.3
ENST00000368060.3
MED23
mediator complex subunit 23
chr5_+_71014990 0.30 ENST00000296777.4
CARTPT
CART prepropeptide
chr6_-_28220002 0.30 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr6_-_163148780 0.30 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
PARK2
parkin RBR E3 ubiquitin protein ligase
chr15_+_51200871 0.30 ENST00000560508.1
AP4E1
adaptor-related protein complex 4, epsilon 1 subunit
chr22_+_50946645 0.29 ENST00000420993.2
ENST00000395698.3
ENST00000395701.3
ENST00000523045.1
ENST00000299821.11
NCAPH2
non-SMC condensin II complex, subunit H2
chr5_+_173763250 0.29 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr3_+_111260856 0.29 ENST00000352690.4
CD96
CD96 molecule
chr4_+_57774042 0.29 ENST00000309042.7
REST
RE1-silencing transcription factor
chr16_-_30569584 0.28 ENST00000252797.2
ENST00000568114.1
ZNF764
AC002310.13
zinc finger protein 764
Uncharacterized protein
chr4_-_46391367 0.28 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr7_+_76139833 0.27 ENST00000257632.5
UPK3B
uroplakin 3B
chr11_-_111741994 0.27 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr13_+_24844819 0.27 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr6_+_112375462 0.27 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr3_+_38017264 0.27 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr1_+_24286287 0.27 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr18_+_3451646 0.27 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr3_-_192445289 0.26 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12
fibroblast growth factor 12
chr16_-_20817753 0.26 ENST00000389345.5
ENST00000300005.3
ENST00000357967.4
ENST00000569729.1
ERI2
ERI1 exoribonuclease family member 2
chr19_+_49497121 0.26 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr21_-_10990830 0.25 ENST00000361285.4
ENST00000342420.5
ENST00000328758.5
TPTE
transmembrane phosphatase with tensin homology
chr20_+_60878005 0.25 ENST00000253003.2
ADRM1
adhesion regulating molecule 1
chr6_+_110299501 0.25 ENST00000414000.2
GPR6
G protein-coupled receptor 6
chr12_+_10658489 0.25 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr2_+_233271546 0.24 ENST00000295453.3
ALPPL2
alkaline phosphatase, placental-like 2
chr22_-_50219548 0.24 ENST00000404034.1
BRD1
bromodomain containing 1
chr2_+_16080659 0.24 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr17_-_29151794 0.24 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chr8_+_97506033 0.23 ENST00000518385.1
SDC2
syndecan 2
chr21_-_10990888 0.23 ENST00000298232.7
TPTE
transmembrane phosphatase with tensin homology
chr1_-_32384693 0.23 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr17_-_3499125 0.23 ENST00000399759.3
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr17_-_40337470 0.23 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr5_-_154230130 0.23 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr3_+_49726932 0.23 ENST00000327697.6
ENST00000432042.1
ENST00000454491.1
RNF123
ring finger protein 123
chr12_-_30887948 0.22 ENST00000433722.2
CAPRIN2
caprin family member 2
chr19_-_6424783 0.22 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr1_+_171217677 0.22 ENST00000402921.2
FMO1
flavin containing monooxygenase 1
chr6_-_26027480 0.22 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr12_-_104531785 0.22 ENST00000551727.1
NFYB
nuclear transcription factor Y, beta
chr10_-_124768300 0.22 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr22_-_30234218 0.22 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr4_+_128886532 0.22 ENST00000444616.1
ENST00000388795.5
C4orf29
chromosome 4 open reading frame 29
chr1_+_26348259 0.22 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr11_-_84028180 0.21 ENST00000280241.8
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_183273477 0.21 ENST00000341319.3
KLHL6
kelch-like family member 6
chr15_-_43559055 0.21 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr15_-_37391614 0.21 ENST00000219869.9
MEIS2
Meis homeobox 2
chr8_-_144241664 0.20 ENST00000342752.4
LY6H
lymphocyte antigen 6 complex, locus H
chrX_+_101380642 0.20 ENST00000372780.1
ENST00000329035.2
TCEAL2
transcription elongation factor A (SII)-like 2
chr7_-_99332719 0.20 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr2_-_37068530 0.20 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr1_-_33502528 0.20 ENST00000354858.6
AK2
adenylate kinase 2
chr13_+_73302047 0.20 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr5_-_58571935 0.20 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 7.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 1.0 GO:0036398 TCR signalosome(GO:0036398)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 18.8 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 1.3 GO:0045179 apical cortex(GO:0045179)
0.1 1.0 GO:0044326 dendritic spine neck(GO:0044326)
0.1 1.3 GO:0097255 R2TP complex(GO:0097255)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.5 GO:0045120 pronucleus(GO:0045120)
0.1 8.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 3.1 GO:0043204 perikaryon(GO:0043204)
0.0 3.3 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0070069 cytochrome complex(GO:0070069)
0.0 1.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 26.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 4.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 0.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 3.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.3 PID INSULIN PATHWAY Insulin Pathway
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 7.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 19.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 1.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 7.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.3 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 18.5 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
1.0 3.1 GO:0034146 B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.7 3.5 GO:0030070 insulin processing(GO:0030070)
0.7 2.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.6 1.8 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.5 1.5 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4 2.2 GO:0070295 renal water absorption(GO:0070295)
0.4 1.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.4 1.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.3 1.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.3 1.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3 1.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 2.2 GO:0008218 bioluminescence(GO:0008218)
0.3 0.8 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.3 2.8 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 2.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.3 1.0 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2 1.6 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 2.4 GO:0051918 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of fibrinolysis(GO:0051918)
0.2 0.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.8 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 0.7 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.2 1.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 1.6 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 0.9 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 1.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.2 2.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 1.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 2.0 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 2.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 1.9 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.7 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 1.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 7.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 5.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 1.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.3 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 1.0 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 1.3 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.3 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.2 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 0.6 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.9 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.9 GO:0030336 negative regulation of cell migration(GO:0030336) negative regulation of cell motility(GO:2000146)
0.0 0.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 1.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.3 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.3 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.9 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158) regulation of miRNA metabolic process(GO:2000628)
0.0 0.6 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0010666 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0010629 negative regulation of gene expression(GO:0010629)
0.0 0.9 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0021915 neural tube development(GO:0021915)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0070268 cornification(GO:0070268)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.6 1.8 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.5 2.2 GO:0015254 glycerol channel activity(GO:0015254)
0.5 2.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 1.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 1.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 1.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 0.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.3 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.3 1.6 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.3 3.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 2.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 1.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 0.9 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 0.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 0.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 1.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 16.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.9 GO:0043199 sulfate binding(GO:0043199)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.9 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.5 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 0.8 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.7 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 2.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 3.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.6 GO:0016853 isomerase activity(GO:0016853)