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ENCODE cell lines, expression (Ernst 2011)

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Results for POU4F1_POU4F3

Z-value: 0.50

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Transcription factors associated with POU4F1_POU4F3

Gene Symbol Gene ID Gene Info
POU4F1
ENSG00000152192.6 POU4F1
POU4F3
ENSG00000091010.4 POU4F3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F1hg19_v2_chr13_-_79177673_79177701-0.204.5e-01Click!
POU4F3hg19_v2_chr5_+_145718587_145718607-0.009.9e-01Click!

Activity profile of POU4F1_POU4F3 motif

Sorted Z-values of POU4F1_POU4F3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F1_POU4F3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_65409438 1.71 ENST00000557049.1
 GPX2
 glutathione peroxidase 2 (gastrointestinal)
chr4_+_74269956 1.58 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
 ALB
 albumin
chr14_-_65409502 1.50 ENST00000389614.5
 GPX2
 glutathione peroxidase 2 (gastrointestinal)
chr17_-_56492989 0.83 ENST00000583753.1
 RNF43
 ring finger protein 43
chr12_+_49740700 0.78 ENST00000549441.2
ENST00000395069.3
 DNAJC22
 DnaJ (Hsp40) homolog, subfamily C, member 22
chr1_+_66458072 0.77 ENST00000423207.2
 PDE4B
 phosphodiesterase 4B, cAMP-specific
chr4_-_16085314 0.77 ENST00000510224.1
 PROM1
 prominin 1
chr4_-_16085340 0.73 ENST00000508167.1
 PROM1
 prominin 1
chr9_-_123812542 0.71 ENST00000223642.1
 C5
 complement component 5
chr5_+_129083772 0.62 ENST00000564719.1
 KIAA1024L
 KIAA1024-like
chr7_-_22234381 0.57 ENST00000458533.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr19_-_36304201 0.57 ENST00000301175.3
 PRODH2
 proline dehydrogenase (oxidase) 2
chr15_+_58724184 0.56 ENST00000433326.2
 LIPC
 lipase, hepatic
chr15_-_20193370 0.53 ENST00000558565.2
 IGHV3OR15-7
 immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_+_22696314 0.52 ENST00000532398.1
ENST00000433790.1
 GAS2
 growth arrest-specific 2
chr15_-_52587945 0.49 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
 MYO5C
 myosin VC
chr17_-_40540586 0.48 ENST00000264657.5
 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
chr22_+_40322595 0.43 ENST00000420971.1
ENST00000544756.1
 GRAP2
 GRB2-related adaptor protein 2
chr22_+_40322623 0.42 ENST00000399090.2
 GRAP2
 GRB2-related adaptor protein 2
chr10_-_11574274 0.42 ENST00000277575.5
 USP6NL
 USP6 N-terminal like
chr17_-_40540377 0.40 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
chr3_-_149375783 0.40 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
 WWTR1
 WW domain containing transcription regulator 1
chr3_-_194072019 0.38 ENST00000429275.1
ENST00000323830.3
 CPN2
 carboxypeptidase N, polypeptide 2
chrX_-_32173579 0.36 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
 DMD
 dystrophin
chr17_-_40540484 0.34 ENST00000588969.1
 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
chr8_+_11666649 0.33 ENST00000528643.1
ENST00000525777.1
 FDFT1
 farnesyl-diphosphate farnesyltransferase 1
chrX_-_15288154 0.33 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
 ASB9
 ankyrin repeat and SOCS box containing 9
chr2_-_88285309 0.33 ENST00000420840.2
 RGPD2
 RANBP2-like and GRIP domain containing 2
chr12_-_6798616 0.32 ENST00000355772.4
ENST00000417772.3
ENST00000396801.3
ENST00000396799.2
 ZNF384
 zinc finger protein 384
chr17_+_7155819 0.31 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
 ELP5
 elongator acetyltransferase complex subunit 5
chr18_-_31803435 0.30 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
 NOL4
 nucleolar protein 4
chr12_-_6798410 0.29 ENST00000361959.3
ENST00000436774.2
ENST00000544482.1
 ZNF384
 zinc finger protein 384
chr12_-_6798523 0.28 ENST00000319770.3
 ZNF384
 zinc finger protein 384
chr2_+_170590321 0.27 ENST00000392647.2
 KLHL23
 kelch-like family member 23
chr22_-_39268308 0.26 ENST00000407418.3
 CBX6
 chromobox homolog 6
chr1_+_73771844 0.25 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
 RP4-598G3.1
 RP4-598G3.1
chr1_+_50574585 0.24 ENST00000371824.1
ENST00000371823.4
 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
chr7_+_100026406 0.24 ENST00000414441.1
 MEPCE
 methylphosphate capping enzyme
chrX_-_39956656 0.23 ENST00000397354.3
ENST00000378444.4
 BCOR
 BCL6 corepressor
chr14_+_21249200 0.23 ENST00000304677.2
 RNASE6
 ribonuclease, RNase A family, k6
chr1_-_160549235 0.22 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
 CD84
 CD84 molecule
chr4_-_69817481 0.22 ENST00000251566.4
 UGT2A3
 UDP glucuronosyltransferase 2 family, polypeptide A3
chr16_-_51185172 0.21 ENST00000251020.4
 SALL1
 spalt-like transcription factor 1
chr20_+_36405665 0.21 ENST00000373469.1
 CTNNBL1
 catenin, beta like 1
chr4_+_68424434 0.21 ENST00000265404.2
ENST00000396225.1
 STAP1
 signal transducing adaptor family member 1
chrX_+_47053208 0.20 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
 UBA1
 ubiquitin-like modifier activating enzyme 1
chr1_+_198608146 0.20 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
 PTPRC
 protein tyrosine phosphatase, receptor type, C
chrX_-_138724994 0.19 ENST00000536274.1
 MCF2
 MCF.2 cell line derived transforming sequence
chr14_-_107049312 0.19 ENST00000390627.2
 IGHV3-53
 immunoglobulin heavy variable 3-53
chr18_-_31803169 0.19 ENST00000590712.1
 NOL4
 nucleolar protein 4
chr14_-_106668095 0.19 ENST00000390606.2
 IGHV3-20
 immunoglobulin heavy variable 3-20
chr17_-_29641084 0.18 ENST00000544462.1
 EVI2B
 ecotropic viral integration site 2B
chr12_+_861717 0.18 ENST00000535572.1
 WNK1
 WNK lysine deficient protein kinase 1
chr3_-_185826855 0.17 ENST00000306376.5
 ETV5
 ets variant 5
chr2_-_101034070 0.17 ENST00000264249.3
 CHST10
 carbohydrate sulfotransferase 10
chr11_-_35441524 0.17 ENST00000395750.1
ENST00000449068.1
 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_-_183387064 0.16 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr2_-_183106641 0.15 ENST00000346717.4
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr15_+_25068773 0.14 ENST00000400100.1
ENST00000400098.1
 SNRPN
 small nuclear ribonucleoprotein polypeptide N
chr10_+_135207623 0.14 ENST00000317502.6
ENST00000432508.3
 MTG1
 mitochondrial ribosome-associated GTPase 1
chr3_-_149470229 0.14 ENST00000473414.1
 COMMD2
 COMM domain containing 2
chr12_-_42631529 0.14 ENST00000548917.1
 YAF2
 YY1 associated factor 2
chr18_+_47088401 0.14 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
 LIPG
 lipase, endothelial
chr19_+_54466179 0.13 ENST00000270458.2
 CACNG8
 calcium channel, voltage-dependent, gamma subunit 8
chr9_+_35673853 0.13 ENST00000378357.4
 CA9
 carbonic anhydrase IX
chr2_-_183387283 0.13 ENST00000435564.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr10_+_135207598 0.13 ENST00000477902.2
 MTG1
 mitochondrial ribosome-associated GTPase 1
chr4_+_106631966 0.13 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
 GSTCD
 glutathione S-transferase, C-terminal domain containing
chr15_-_65426174 0.13 ENST00000204549.4
 PDCD7
 programmed cell death 7
chr6_-_44281043 0.13 ENST00000244571.4
 AARS2
 alanyl-tRNA synthetase 2, mitochondrial
chr12_-_89746173 0.13 ENST00000308385.6
 DUSP6
 dual specificity phosphatase 6
chr13_-_46756351 0.12 ENST00000323076.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_21270995 0.12 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
 RNASE1
 ribonuclease, RNase A family, 1 (pancreatic)
chr22_-_30970560 0.12 ENST00000402369.1
ENST00000406361.1
 GAL3ST1
 galactose-3-O-sulfotransferase 1
chr1_+_81771806 0.12 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr7_-_20256965 0.12 ENST00000400331.5
ENST00000332878.4
 MACC1
 metastasis associated in colon cancer 1
chr1_+_101003687 0.12 ENST00000315033.4
 GPR88
 G protein-coupled receptor 88
chr3_-_52860850 0.12 ENST00000441637.2
 ITIH4
 inter-alpha-trypsin inhibitor heavy chain family, member 4
chr3_-_58613323 0.12 ENST00000474531.1
ENST00000465970.1
 FAM107A
 family with sequence similarity 107, member A
chr7_-_100026280 0.11 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
 ZCWPW1
 zinc finger, CW type with PWWP domain 1
chrX_-_138724677 0.11 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
 MCF2
 MCF.2 cell line derived transforming sequence
chr14_+_39703084 0.11 ENST00000553728.1
 RP11-407N17.3
 cTAGE family member 5 isoform 4
chr1_-_95538492 0.11 ENST00000370205.5
 ALG14
 ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr12_-_23737534 0.11 ENST00000396007.2
 SOX5
 SRY (sex determining region Y)-box 5
chr11_-_8290263 0.11 ENST00000428101.2
 LMO1
 LIM domain only 1 (rhombotin 1)
chr4_+_102711764 0.10 ENST00000322953.4
ENST00000428908.1
 BANK1
 B-cell scaffold protein with ankyrin repeats 1
chr1_-_154580616 0.10 ENST00000368474.4
 ADAR
 adenosine deaminase, RNA-specific
chr14_-_21270561 0.10 ENST00000412779.2
 RNASE1
 ribonuclease, RNase A family, 1 (pancreatic)
chr3_+_70048881 0.10 ENST00000483525.1
 RP11-460N16.1
 RP11-460N16.1
chr2_+_87135076 0.09 ENST00000409776.2
 RGPD1
 RANBP2-like and GRIP domain containing 1
chr16_+_48278178 0.09 ENST00000285737.4
ENST00000535754.1
 LONP2
 lon peptidase 2, peroxisomal
chr22_+_39101728 0.09 ENST00000216044.5
ENST00000484657.1
 GTPBP1
 GTP binding protein 1
chr7_-_115670792 0.09 ENST00000265440.7
ENST00000393485.1
 TFEC
 transcription factor EC
chr5_-_11588907 0.09 ENST00000513598.1
ENST00000503622.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr14_+_39583427 0.09 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
 GEMIN2
 gem (nuclear organelle) associated protein 2
chr12_-_100486668 0.09 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
 UHRF1BP1L
 UHRF1 binding protein 1-like
chr6_-_76782371 0.09 ENST00000369950.3
ENST00000369963.3
 IMPG1
 interphotoreceptor matrix proteoglycan 1
chr11_-_35441597 0.08 ENST00000395753.1
 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_11589131 0.08 ENST00000511377.1
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr17_+_45728427 0.08 ENST00000540627.1
 KPNB1
 karyopherin (importin) beta 1
chr8_-_125577940 0.08 ENST00000519168.1
ENST00000395508.2
 MTSS1
 metastasis suppressor 1
chr1_+_67773044 0.08 ENST00000262345.1
ENST00000371000.1
 IL12RB2
 interleukin 12 receptor, beta 2
chr16_+_31366536 0.08 ENST00000562522.1
 ITGAX
 integrin, alpha X (complement component 3 receptor 4 subunit)
chr7_-_115670804 0.08 ENST00000320239.7
 TFEC
 transcription factor EC
chr12_+_16109519 0.08 ENST00000526530.1
 DERA
 deoxyribose-phosphate aldolase (putative)
chr2_+_87144738 0.07 ENST00000559485.1
 RGPD1
 RANBP2-like and GRIP domain containing 1
chr14_-_54908043 0.07 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
 CNIH1
 cornichon family AMPA receptor auxiliary protein 1
chr6_+_126102292 0.07 ENST00000368357.3
 NCOA7
 nuclear receptor coactivator 7
chr14_+_31494672 0.07 ENST00000542754.2
ENST00000313566.6
 AP4S1
 adaptor-related protein complex 4, sigma 1 subunit
chr7_-_100425112 0.07 ENST00000358173.3
 EPHB4
 EPH receptor B4
chr9_-_21166659 0.06 ENST00000380225.1
 IFNA21
 interferon, alpha 21
chr19_-_18632861 0.06 ENST00000262809.4
 ELL
 elongation factor RNA polymerase II
chr10_-_115904361 0.06 ENST00000428953.1
ENST00000543782.1
 C10orf118
 chromosome 10 open reading frame 118
chr4_-_122085469 0.06 ENST00000057513.3
 TNIP3
 TNFAIP3 interacting protein 3
chrX_+_41583408 0.06 ENST00000302548.4
 GPR82
 G protein-coupled receptor 82
chr20_+_57875758 0.06 ENST00000395654.3
 EDN3
 endothelin 3
chr1_+_79115503 0.06 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
 IFI44
 interferon-induced protein 44
chr19_-_53696587 0.06 ENST00000396424.3
ENST00000600412.1
 ZNF665
 zinc finger protein 665
chr1_-_54303934 0.06 ENST00000537333.1
 NDC1
 NDC1 transmembrane nucleoporin
chr4_-_122744998 0.06 ENST00000274026.5
 CCNA2
 cyclin A2
chr19_+_16940198 0.05 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
 SIN3B
 SIN3 transcription regulator family member B
chr1_+_160336851 0.05 ENST00000302101.5
 NHLH1
 nescient helix loop helix 1
chr1_-_54303949 0.05 ENST00000234725.8
 NDC1
 NDC1 transmembrane nucleoporin
chr12_-_51611477 0.05 ENST00000389243.4
 POU6F1
 POU class 6 homeobox 1
chr10_+_104613980 0.05 ENST00000339834.5
 C10orf32
 chromosome 10 open reading frame 32
chr18_+_32397918 0.05 ENST00000590727.1
ENST00000601125.1
 DTNA
 dystrobrevin, alpha
chr21_-_37914898 0.05 ENST00000399136.1
 CLDN14
 claudin 14
chr5_-_134871639 0.05 ENST00000314744.4
 NEUROG1
 neurogenin 1
chr17_+_29664830 0.04 ENST00000444181.2
ENST00000417592.2
 NF1
 neurofibromin 1
chr5_+_140501581 0.04 ENST00000194152.1
 PCDHB4
 protocadherin beta 4
chr13_-_70682590 0.04 ENST00000377844.4
 KLHL1
 kelch-like family member 1
chr17_-_50236039 0.04 ENST00000451037.2
 CA10
 carbonic anhydrase X
chr16_+_31366455 0.04 ENST00000268296.4
 ITGAX
 integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_+_158900568 0.04 ENST00000458222.1
 PYHIN1
 pyrin and HIN domain family, member 1
chr11_+_120973375 0.04 ENST00000264037.2
 TECTA
 tectorin alpha
chr5_-_77844974 0.04 ENST00000515007.2
 LHFPL2
 lipoma HMGIC fusion partner-like 2
chr1_-_156470515 0.03 ENST00000340875.5
ENST00000368240.2
ENST00000353795.3
 MEF2D
 myocyte enhancer factor 2D
chr5_-_41261540 0.03 ENST00000263413.3
 C6
 complement component 6
chr16_+_619931 0.03 ENST00000321878.5
ENST00000439574.1
ENST00000026218.5
ENST00000470411.2
 PIGQ
 phosphatidylinositol glycan anchor biosynthesis, class Q
chr12_+_41831485 0.03 ENST00000539469.2
ENST00000298919.7
 PDZRN4
 PDZ domain containing ring finger 4
chr15_+_74422585 0.03 ENST00000561740.1
ENST00000435464.1
ENST00000453268.2
 ISLR2
 immunoglobulin superfamily containing leucine-rich repeat 2
chr14_+_31494841 0.03 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
 AP4S1
 adaptor-related protein complex 4, sigma 1 subunit
chr18_+_61575200 0.03 ENST00000238508.3
 SERPINB10
 serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr4_+_37962018 0.03 ENST00000504686.1
 PTTG2
 pituitary tumor-transforming 2
chr18_+_29027696 0.03 ENST00000257189.4
 DSG3
 desmoglein 3
chr10_-_6104253 0.02 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
 IL2RA
 interleukin 2 receptor, alpha
chr13_+_52586517 0.02 ENST00000523764.1
ENST00000521508.1
 ALG11
 ALG11, alpha-1,2-mannosyltransferase
chrX_-_107975917 0.02 ENST00000563887.1
 RP6-24A23.6
 Uncharacterized protein
chr20_+_30063067 0.02 ENST00000201979.2
 REM1
 RAS (RAD and GEM)-like GTP-binding 1
chr5_-_58295712 0.02 ENST00000317118.8
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr2_-_70475730 0.02 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
 TIA1
 TIA1 cytotoxic granule-associated RNA binding protein
chr1_-_216978709 0.02 ENST00000360012.3
 ESRRG
 estrogen-related receptor gamma
chr10_-_22292613 0.02 ENST00000376980.3
 DNAJC1
 DnaJ (Hsp40) homolog, subfamily C, member 1
chr22_-_43010928 0.02 ENST00000348657.2
ENST00000252115.5
 POLDIP3
 polymerase (DNA-directed), delta interacting protein 3
chr17_+_18759612 0.01 ENST00000432893.2
ENST00000414602.1
ENST00000574522.1
ENST00000570450.1
ENST00000419071.2
 PRPSAP2
 phosphoribosyl pyrophosphate synthetase-associated protein 2
chr9_+_135906076 0.01 ENST00000372097.5
ENST00000440319.1
 GTF3C5
 general transcription factor IIIC, polypeptide 5, 63kDa
chr12_-_102224704 0.01 ENST00000299314.7
 GNPTAB
 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr4_-_68749699 0.01 ENST00000545541.1
 TMPRSS11D
 transmembrane protease, serine 11D
chr2_+_204732487 0.01 ENST00000302823.3
 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
chr1_-_33430286 0.01 ENST00000373456.7
ENST00000356990.5
ENST00000235150.4
 RNF19B
 ring finger protein 19B
chr4_-_25032501 0.01 ENST00000382114.4
 LGI2
 leucine-rich repeat LGI family, member 2
chr9_-_215744 0.01 ENST00000382387.2
 C9orf66
 chromosome 9 open reading frame 66
chr10_+_79793518 0.01 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
 RPS24
 ribosomal protein S24
chr12_-_111926342 0.01 ENST00000389154.3
 ATXN2
 ataxin 2
chr9_+_34458771 0.01 ENST00000437363.1
ENST00000242317.4
 DNAI1
 dynein, axonemal, intermediate chain 1
chr2_+_202047843 0.00 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
 CASP10
 caspase 10, apoptosis-related cysteine peptidase
chr2_+_29320571 0.00 ENST00000401605.1
ENST00000401617.2
 CLIP4
 CAP-GLY domain containing linker protein family, member 4
chr11_+_86085778 0.00 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
 CCDC81
 coiled-coil domain containing 81
chr12_+_10658201 0.00 ENST00000322446.3
 EIF2S3L
 Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chrX_+_65382381 0.00 ENST00000519389.1
 HEPH
 hephaestin
chr17_-_49124230 0.00 ENST00000510283.1
ENST00000510855.1
 SPAG9
 sperm associated antigen 9

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 3.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.6 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.5 GO:0042805 actinin binding(GO:0042805)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.4 1.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.3 1.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 0.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.2 GO:0072092 olfactory bulb mitral cell layer development(GO:0061034) ureteric bud invasion(GO:0072092)
0.1 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.3 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.0 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.0 0.6 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.0 3.0 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.1 GO:0098722 asymmetric neuroblast division(GO:0055059) asymmetric stem cell division(GO:0098722)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade