ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
POU5F1 Links Ensembl NCBI GeneCards UniProt	ENSG00000204531.11	POU5F1
POU2F3 Links Ensembl NCBI GeneCards UniProt	ENSG00000137709.5	POU2F3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
POU2F3	hg19_v2_chr11_+_120107344_120107351	0.21	4.3e-01	Click!
POU5F1	hg19_v2_chr6_-_31138439_31138475	0.06	8.2e-01	Click!

View svg image
View png image

Promoter	Score	Transcript	Gene	Gene Info
chr16_+_32077386	9.17	ENST00000354689.6	IGHV3OR16-9	immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr22_+_23077065	7.43	ENST00000390310.2	IGLV2-18	immunoglobulin lambda variable 2-18
chr10_-_98031310	6.21	ENST00000427367.2 ENST00000413476.2	BLNK	B-cell linker
chr10_-_98031265	6.10	ENST00000224337.5 ENST00000371176.2	BLNK	B-cell linker
chr16_+_23847267	5.97	ENST00000321728.7	PRKCB	protein kinase C, beta
chr22_+_23134974	5.59	ENST00000390314.2	IGLV2-11	immunoglobulin lambda variable 2-11
chr14_-_106573756	5.33	ENST00000390601.2	IGHV3-11	immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr16_+_23847339	4.91	ENST00000303531.7	PRKCB	protein kinase C, beta
chr13_-_99959641	4.58	ENST00000376414.4	GPR183	G protein-coupled receptor 183
chr22_+_22550113	4.47	ENST00000390285.3	IGLV6-57	immunoglobulin lambda variable 6-57
chr14_-_107049312	3.97	ENST00000390627.2	IGHV3-53	immunoglobulin heavy variable 3-53
chr14_-_106552755	3.82	ENST00000390600.2	IGHV3-9	immunoglobulin heavy variable 3-9
chr16_+_33605231	3.79	ENST00000570121.2	IGHV3OR16-12	immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr14_-_106539557	3.71	ENST00000390599.2	IGHV1-8	immunoglobulin heavy variable 1-8
chr3_-_107777208	3.70	ENST00000398258.3	CD47	CD47 molecule
chr22_+_23040274	3.70	ENST00000390306.2	IGLV2-23	immunoglobulin lambda variable 2-23
chr14_-_106733624	3.43	ENST00000390610.2	IGHV1-24	immunoglobulin heavy variable 1-24
chr4_-_71532339	3.37	ENST00000254801.4	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr8_+_56792355	3.19	ENST00000519728.1	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr14_-_106692191	3.15	ENST00000390607.2	IGHV3-21	immunoglobulin heavy variable 3-21
chr3_+_98250743	3.10	ENST00000284311.3	GPR15	G protein-coupled receptor 15
chr16_+_33020496	3.10	ENST00000565407.2	IGHV3OR16-8	immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr19_-_39108568	3.02	ENST00000586296.1	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr14_-_106926724	2.99	ENST00000434710.1	IGHV3-43	immunoglobulin heavy variable 3-43
chr22_+_22930626	2.94	ENST00000390302.2	IGLV2-33	immunoglobulin lambda variable 2-33 (non-functional)
chr19_-_39108552	2.93	ENST00000591517.1	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr8_+_56792377	2.90	ENST00000520220.2	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr18_-_53089723	2.89	ENST00000561992.1 ENST00000562512.2	TCF4	transcription factor 4
chr22_+_23165153	2.88	ENST00000390317.2	IGLV2-8	immunoglobulin lambda variable 2-8
chr16_-_33647696	2.82	ENST00000558425.1 ENST00000569103.2	RP11-812E19.9	Uncharacterized protein
chr22_+_23101182	2.76	ENST00000390312.2	IGLV2-14	immunoglobulin lambda variable 2-14
chr6_-_32784687	2.65	ENST00000447394.1 ENST00000438763.2	HLA-DOB	major histocompatibility complex, class II, DO beta
chr14_-_106845789	2.61	ENST00000390617.2	IGHV3-35	immunoglobulin heavy variable 3-35 (non-functional)
chr6_-_32557610	2.61	ENST00000360004.5	HLA-DRB1	major histocompatibility complex, class II, DR beta 1
chr6_+_32407619	2.59	ENST00000395388.2 ENST00000374982.5	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr14_-_106963409	2.53	ENST00000390621.2	IGHV1-45	immunoglobulin heavy variable 1-45
chr14_-_107078851	2.53	ENST00000390628.2	IGHV1-58	immunoglobulin heavy variable 1-58
chr17_+_67410832	2.39	ENST00000590474.1	MAP2K6	mitogen-activated protein kinase kinase 6
chr15_-_20193370	2.35	ENST00000558565.2	IGHV3OR15-7	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr6_-_27114577	2.24	ENST00000356950.1 ENST00000396891.4	HIST1H2BK	histone cluster 1, H2bk
chr1_-_154832316	2.20	ENST00000361147.4	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr18_-_52989525	2.12	ENST00000457482.3	TCF4	transcription factor 4
chr2_+_90077680	2.07	ENST00000390270.2	IGKV3D-20	immunoglobulin kappa variable 3D-20
chrX_+_154611749	2.07	ENST00000369505.3	F8A2	coagulation factor VIII-associated 2
chr14_-_106994333	2.04	ENST00000390624.2	IGHV3-48	immunoglobulin heavy variable 3-48
chrX_+_154114635	2.04	ENST00000369446.2	F8A1	coagulation factor VIII-associated 1
chr1_+_156119798	2.00	ENST00000355014.2	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr22_+_22764088	2.00	ENST00000390299.2	IGLV1-40	immunoglobulin lambda variable 1-40
chr10_-_64576105	1.98	ENST00000242480.3 ENST00000411732.1	EGR2	early growth response 2
chr19_+_35820064	1.97	ENST00000341773.6 ENST00000600131.1 ENST00000270311.6 ENST00000595780.1 ENST00000597916.1 ENST00000593867.1 ENST00000600424.1 ENST00000599811.1 ENST00000536635.2 ENST00000085219.5 ENST00000544992.2 ENST00000419549.2	CD22	CD22 molecule
chr2_-_89399845	1.97	ENST00000479981.1	IGKV1-16	immunoglobulin kappa variable 1-16
chr4_+_41258786	1.97	ENST00000503431.1 ENST00000284440.4 ENST00000508768.1 ENST00000512788.1	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chrX_+_80457442	1.95	ENST00000373212.5	SH3BGRL	SH3 domain binding glutamic acid-rich protein like
chr5_+_49961727	1.95	ENST00000505697.2 ENST00000503750.2 ENST00000514342.2	PARP8	poly (ADP-ribose) polymerase family, member 8
chr19_-_39108643	1.94	ENST00000396857.2	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr2_+_89184868	1.94	ENST00000390243.2	IGKV4-1	immunoglobulin kappa variable 4-1
chrX_-_80457385	1.93	ENST00000451455.1 ENST00000436386.1 ENST00000358130.2	HMGN5	high mobility group nucleosome binding domain 5
chr12_+_113344755	1.92	ENST00000550883.1	OAS1	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr22_-_24096562	1.92	ENST00000398465.3	VPREB3	pre-B lymphocyte 3
chr4_-_38806404	1.91	ENST00000308979.2 ENST00000505940.1 ENST00000515861.1	TLR1	toll-like receptor 1
chr7_-_37024665	1.90	ENST00000396040.2	ELMO1	engulfment and cell motility 1
chrX_+_12993202	1.86	ENST00000451311.2 ENST00000380636.1	TMSB4X	thymosin beta 4, X-linked
chr3_-_127541194	1.86	ENST00000453507.2	MGLL	monoglyceride lipase
chr13_-_47012325	1.84	ENST00000409879.2	KIAA0226L	KIAA0226-like
chr18_-_52989217	1.82	ENST00000570287.2	TCF4	transcription factor 4
chr5_-_111091948	1.82	ENST00000447165.2	NREP	neuronal regeneration related protein
chr16_+_32063311	1.80	ENST00000426099.1	AC142381.1	AC142381.1
chr3_-_16524357	1.77	ENST00000432519.1	RFTN1	raftlin, lipid raft linker 1
chr2_+_90139056	1.76	ENST00000492446.1	IGKV1D-16	immunoglobulin kappa variable 1D-16
chr14_-_107219365	1.75	ENST00000424969.2	IGHV3-74	immunoglobulin heavy variable 3-74
chr1_-_31230650	1.72	ENST00000294507.3	LAPTM5	lysosomal protein transmembrane 5
chr2_+_68592305	1.71	ENST00000234313.7	PLEK	pleckstrin
chr22_+_22712087	1.71	ENST00000390294.2	IGLV1-47	immunoglobulin lambda variable 1-47
chrX_+_12993336	1.70	ENST00000380635.1	TMSB4X	thymosin beta 4, X-linked
chr21_+_10862622	1.68	ENST00000302092.5 ENST00000559480.1	IGHV1OR21-1	immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr12_+_25205568	1.68	ENST00000548766.1 ENST00000556887.1	LRMP	lymphoid-restricted membrane protein
chrX_-_48776292	1.68	ENST00000376509.4	PIM2	pim-2 oncogene
chr12_+_14518598	1.66	ENST00000261168.4 ENST00000538511.1 ENST00000545723.1 ENST00000543189.1 ENST00000536444.1	ATF7IP	activating transcription factor 7 interacting protein
chr14_-_106518922	1.65	ENST00000390598.2	IGHV3-7	immunoglobulin heavy variable 3-7
chr11_-_73687997	1.65	ENST00000545212.1	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr2_-_175547571	1.65	ENST00000409415.3 ENST00000359761.3 ENST00000272746.5	WIPF1	WAS/WASL interacting protein family, member 1
chr12_+_113344582	1.64	ENST00000202917.5 ENST00000445409.2 ENST00000452357.2	OAS1	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_25205666	1.64	ENST00000547044.1	LRMP	lymphoid-restricted membrane protein
chr13_-_99910673	1.57	ENST00000397473.2 ENST00000397470.2	GPR18	G protein-coupled receptor 18
chr2_-_89521942	1.54	ENST00000482769.1	IGKV2-28	immunoglobulin kappa variable 2-28
chr3_+_186648307	1.54	ENST00000457772.2 ENST00000455441.1 ENST00000427315.1	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr17_-_62009621	1.52	ENST00000349817.2 ENST00000392795.3	CD79B	CD79b molecule, immunoglobulin-associated beta
chr7_+_116660246	1.49	ENST00000434836.1 ENST00000393443.1 ENST00000465133.1 ENST00000477742.1 ENST00000393447.4 ENST00000393444.3	ST7	suppression of tumorigenicity 7
chr3_+_186648274	1.49	ENST00000169298.3	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr18_-_53257027	1.48	ENST00000568740.1 ENST00000564403.2 ENST00000537578.1	TCF4	transcription factor 4
chr14_-_106471723	1.45	ENST00000390595.2	IGHV1-3	immunoglobulin heavy variable 1-3
chr2_-_38303218	1.44	ENST00000407341.1 ENST00000260630.3	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1
chr16_+_33006369	1.43	ENST00000425181.3	IGHV3OR16-10	immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr15_-_22448819	1.42	ENST00000604066.1	IGHV1OR15-1	immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr22_+_22735135	1.41	ENST00000390297.2	IGLV1-44	immunoglobulin lambda variable 1-44
chr18_-_53255766	1.39	ENST00000566286.1 ENST00000564999.1 ENST00000566279.1 ENST00000354452.3 ENST00000356073.4	TCF4	transcription factor 4
chr3_+_141106643	1.38	ENST00000514251.1	ZBTB38	zinc finger and BTB domain containing 38
chr17_-_62009702	1.37	ENST00000006750.3	CD79B	CD79b molecule, immunoglobulin-associated beta
chr5_+_153570285	1.37	ENST00000425427.2 ENST00000297107.6	GALNT10	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr12_+_25205446	1.36	ENST00000557489.1 ENST00000354454.3 ENST00000536173.1	LRMP	lymphoid-restricted membrane protein
chr22_-_24096630	1.35	ENST00000248948.3	VPREB3	pre-B lymphocyte 3
chr1_+_32666188	1.35	ENST00000421922.2	CCDC28B	coiled-coil domain containing 28B
chr11_+_313503	1.33	ENST00000528780.1 ENST00000328221.5	IFITM1	interferon induced transmembrane protein 1
chr5_+_49962772	1.29	ENST00000281631.5 ENST00000513738.1 ENST00000503665.1 ENST00000514067.2 ENST00000503046.1	PARP8	poly (ADP-ribose) polymerase family, member 8
chr12_+_113354341	1.28	ENST00000553152.1	OAS1	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_89998789	1.28	ENST00000453166.2	IGKV2D-28	immunoglobulin kappa variable 2D-28
chr15_-_80263506	1.27	ENST00000335661.6	BCL2A1	BCL2-related protein A1
chr10_+_11206925	1.26	ENST00000354440.2 ENST00000315874.4 ENST00000427450.1	CELF2	CUGBP, Elav-like family member 2
chr2_-_89340242	1.25	ENST00000480492.1	IGKV1-12	immunoglobulin kappa variable 1-12
chr6_-_24877490	1.24	ENST00000540914.1 ENST00000378023.4	FAM65B	family with sequence similarity 65, member B
chr11_+_102188224	1.22	ENST00000263464.3	BIRC3	baculoviral IAP repeat containing 3
chr22_+_22385332	1.22	ENST00000390282.2	IGLV4-69	immunoglobulin lambda variable 4-69
chr3_+_178253993	1.18	ENST00000420517.2 ENST00000452583.1	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr7_-_37488834	1.18	ENST00000310758.4	ELMO1	engulfment and cell motility 1
chr7_+_64363625	1.18	ENST00000476120.1 ENST00000319636.5 ENST00000545510.1	ZNF273	zinc finger protein 273
chr2_+_90153696	1.17	ENST00000417279.2	IGKV3D-15	immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr1_+_192544857	1.17	ENST00000367459.3 ENST00000469578.2	RGS1	regulator of G-protein signaling 1
chr11_+_102188272	1.17	ENST00000532808.1	BIRC3	baculoviral IAP repeat containing 3
chr14_-_107114267	1.16	ENST00000454421.2	IGHV3-64	immunoglobulin heavy variable 3-64
chr14_-_106816253	1.13	ENST00000390615.2	IGHV3-33	immunoglobulin heavy variable 3-33
chr12_-_102874416	1.11	ENST00000392904.1 ENST00000337514.6	IGF1	insulin-like growth factor 1 (somatomedin C)
chr12_-_102874378	1.11	ENST00000456098.1	IGF1	insulin-like growth factor 1 (somatomedin C)
chr16_-_74808710	1.10	ENST00000219368.3 ENST00000544337.1	FA2H	fatty acid 2-hydroxylase
chr12_-_772901	1.09	ENST00000305108.4	NINJ2	ninjurin 2
chr2_+_90198535	1.07	ENST00000390276.2	IGKV1D-12	immunoglobulin kappa variable 1D-12
chr5_+_49962495	1.06	ENST00000515175.1	PARP8	poly (ADP-ribose) polymerase family, member 8
chr7_-_87856280	1.05	ENST00000490437.1 ENST00000431660.1	SRI	sorcin
chr3_-_58200398	1.05	ENST00000318316.3 ENST00000460422.1 ENST00000483681.1	DNASE1L3	deoxyribonuclease I-like 3
chr14_-_106866934	1.05	ENST00000390618.2	IGHV3-38	immunoglobulin heavy variable 3-38 (non-functional)
chr7_-_87856303	1.04	ENST00000394641.3	SRI	sorcin
chr14_+_105952648	1.03	ENST00000330233.7	CRIP1	cysteine-rich protein 1 (intestinal)
chr12_-_91573132	1.00	ENST00000550563.1 ENST00000546370.1	DCN	decorin
chr9_+_2029019	1.00	ENST00000382194.1	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_-_111092930	1.00	ENST00000257435.7	NREP	neuronal regeneration related protein
chr8_-_102803163	0.99	ENST00000523645.1 ENST00000520346.1 ENST00000220931.6 ENST00000522448.1 ENST00000522951.1 ENST00000522252.1 ENST00000519098.1	NCALD	neurocalcin delta
chr1_+_28206150	0.98	ENST00000456990.1	THEMIS2	thymocyte selection associated family member 2
chr12_-_7245125	0.98	ENST00000542285.1 ENST00000540610.1	C1R	complement component 1, r subcomponent
chr15_-_78526855	0.96	ENST00000541759.1 ENST00000558130.1	ACSBG1	acyl-CoA synthetase bubblegum family member 1
chr7_-_144435985	0.96	ENST00000549981.1	TPK1	thiamin pyrophosphokinase 1
chr12_+_113344811	0.95	ENST00000551241.1 ENST00000553185.1 ENST00000550689.1	OAS1	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_89442621	0.95	ENST00000492167.1	IGKV3-20	immunoglobulin kappa variable 3-20
chr16_+_33629600	0.94	ENST00000562905.2	IGHV3OR16-13	immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr4_+_68424434	0.93	ENST00000265404.2 ENST00000396225.1	STAP1	signal transducing adaptor family member 1
chr20_-_7921090	0.92	ENST00000378789.3	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr1_-_149783914	0.90	ENST00000369167.1 ENST00000427880.2 ENST00000545683.1	HIST2H2BF	histone cluster 2, H2bf
chr12_-_7818474	0.90	ENST00000229304.4	APOBEC1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr13_-_41593425	0.88	ENST00000239882.3	ELF1	E74-like factor 1 (ets domain transcription factor)
chr14_-_107170409	0.87	ENST00000390633.2	IGHV1-69	immunoglobulin heavy variable 1-69
chr5_-_142783694	0.85	ENST00000394466.2	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr21_-_35014027	0.84	ENST00000399442.1 ENST00000413017.2 ENST00000445393.1 ENST00000417979.1 ENST00000426935.1 ENST00000381540.3 ENST00000361534.2 ENST00000381554.3	CRYZL1	crystallin, zeta (quinone reductase)-like 1
chr6_-_29527702	0.82	ENST00000377050.4	UBD	ubiquitin D
chr14_-_107131560	0.82	ENST00000390632.2	IGHV3-66	immunoglobulin heavy variable 3-66
chr2_+_58134756	0.82	ENST00000435505.2 ENST00000417641.2	VRK2	vaccinia related kinase 2
chr14_-_107283278	0.81	ENST00000390639.2	IGHV7-81	immunoglobulin heavy variable 7-81 (non-functional)
chr19_+_53030906	0.81	ENST00000359798.4 ENST00000465448.1 ENST00000486474.1 ENST00000461779.1	ZNF808	zinc finger protein 808
chr3_+_5229356	0.80	ENST00000256497.4	EDEM1	ER degradation enhancer, mannosidase alpha-like 1
chr11_-_46142948	0.80	ENST00000257821.4	PHF21A	PHD finger protein 21A
chr19_-_17516449	0.80	ENST00000252593.6	BST2	bone marrow stromal cell antigen 2
chrX_-_154688276	0.79	ENST00000369445.2	F8A3	coagulation factor VIII-associated 3
chr14_-_106586656	0.79	ENST00000390602.2	IGHV3-13	immunoglobulin heavy variable 3-13
chr4_+_75858318	0.79	ENST00000307428.7	PARM1	prostate androgen-regulated mucin-like protein 1
chr1_-_226926864	0.78	ENST00000429204.1 ENST00000366784.1	ITPKB	inositol-trisphosphate 3-kinase B
chr15_-_20170354	0.78	ENST00000338912.5	IGHV1OR15-9	immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr3_+_48264816	0.78	ENST00000296435.2 ENST00000576243.1	CAMP	cathelicidin antimicrobial peptide
chr1_-_23886285	0.78	ENST00000374561.5	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_+_79115503	0.77	ENST00000370747.4 ENST00000438486.1 ENST00000545124.1	IFI44	interferon-induced protein 44
chr7_+_90338712	0.77	ENST00000265741.3 ENST00000406263.1	CDK14	cyclin-dependent kinase 14
chr2_+_189839046	0.76	ENST00000304636.3 ENST00000317840.5	COL3A1	collagen, type III, alpha 1
chr2_-_89597542	0.76	ENST00000465170.1	IGKV1-37	immunoglobulin kappa variable 1-37 (non-functional)
chrX_-_73072534	0.74	ENST00000429829.1	XIST	X inactive specific transcript (non-protein coding)
chr18_-_53069419	0.74	ENST00000570177.2	TCF4	transcription factor 4
chr12_-_102874102	0.73	ENST00000392905.2	IGF1	insulin-like growth factor 1 (somatomedin C)
chr3_+_134514093	0.73	ENST00000398015.3	EPHB1	EPH receptor B1
chr1_+_101702417	0.73	ENST00000305352.6	S1PR1	sphingosine-1-phosphate receptor 1
chr4_+_26322409	0.73	ENST00000514807.1 ENST00000348160.4 ENST00000509158.1 ENST00000355476.3	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr15_+_75080883	0.73	ENST00000567571.1	CSK	c-src tyrosine kinase
chr14_-_106725723	0.72	ENST00000390609.2	IGHV3-23	immunoglobulin heavy variable 3-23
chr19_-_41903161	0.71	ENST00000602129.1 ENST00000593771.1 ENST00000596905.1 ENST00000221233.4	EXOSC5	exosome component 5
chr14_-_106453155	0.71	ENST00000390594.2	IGHV1-2	immunoglobulin heavy variable 1-2
chr3_+_130650738	0.70	ENST00000504612.1	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr5_+_153570319	0.69	ENST00000377661.2	GALNT10	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr4_-_153332886	0.69	ENST00000603841.1	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr6_-_26032288	0.68	ENST00000244661.2	HIST1H3B	histone cluster 1, H3b
chr7_+_64126535	0.68	ENST00000344930.3	ZNF107	zinc finger protein 107
chrX_-_106960285	0.68	ENST00000503515.1 ENST00000372397.2	TSC22D3	TSC22 domain family, member 3
chr6_-_26216872	0.67	ENST00000244601.3	HIST1H2BG	histone cluster 1, H2bg
chr12_+_54447637	0.67	ENST00000609810.1 ENST00000430889.2	HOXC4 HOXC4	homeobox C4 Homeobox protein Hox-C4
chr6_-_143266297	0.67	ENST00000367603.2	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2
chr12_-_91576429	0.67	ENST00000552145.1 ENST00000546745.1	DCN	decorin
chr2_+_61108650	0.67	ENST00000295025.8	REL	v-rel avian reticuloendotheliosis viral oncogene homolog
chr5_-_111092873	0.66	ENST00000509025.1 ENST00000515855.1	NREP	neuronal regeneration related protein
chr10_+_89622870	0.66	ENST00000371953.3	PTEN	phosphatase and tensin homolog
chr17_-_47841485	0.66	ENST00000506156.1 ENST00000240364.2	FAM117A	family with sequence similarity 117, member A
chr12_-_102874330	0.66	ENST00000307046.8	IGF1	insulin-like growth factor 1 (somatomedin C)
chrX_+_108779004	0.65	ENST00000218004.1	NXT2	nuclear transport factor 2-like export factor 2
chr4_+_75858290	0.65	ENST00000513238.1	PARM1	prostate androgen-regulated mucin-like protein 1
chr12_-_91576561	0.64	ENST00000547568.2 ENST00000552962.1	DCN	decorin
chr2_+_97426631	0.64	ENST00000377075.2	CNNM4	cyclin M4
chr14_+_72052983	0.63	ENST00000358550.2	SIPA1L1	signal-induced proliferation-associated 1 like 1
chr14_+_79745746	0.63	ENST00000281127.7	NRXN3	neurexin 3

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.6	10.9	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
1.0	3.0	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.9	48.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.8	5.9	GO:0043208	glycosphingolipid binding(GO:0043208)
0.8	10.4	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7	13.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7	4.6	GO:0008142	oxysterol binding(GO:0008142)
0.6	1.9	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.6	5.8	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.5	2.0	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.4	83.3	GO:0003823	antigen binding(GO:0003823)
0.4	2.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.4	3.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.4	6.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.3	1.0	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.3	0.9	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.3	0.9	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.3	0.8	GO:0072510	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2	1.7	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.2	0.7	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2	0.9	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2	0.5	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	0.7	GO:0046625	sphingolipid binding(GO:0046625)
0.1	1.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.8	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	2.1	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.5	GO:0016160	amylase activity(GO:0016160)
0.1	0.8	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	0.5	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	0.9	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	1.3	GO:0000150	recombinase activity(GO:0000150)
0.1	1.0	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	0.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.5	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.5	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.3	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	2.7	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.3	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.1	3.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.5	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.1	0.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.1	0.4	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1	3.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	1.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	1.7	GO:0005522	profilin binding(GO:0005522)
0.1	0.6	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	0.6	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1	0.5	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	1.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.4	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	1.1	GO:0003680	AT DNA binding(GO:0003680)
0.1	2.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	0.5	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	1.8	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.2	GO:0008431	vitamin E binding(GO:0008431)
0.1	0.7	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.8	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.1	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.1	0.8	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.2	GO:0035276	ethanol binding(GO:0035276)
0.1	0.5	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.1	GO:0032427	GBD domain binding(GO:0032427)
0.1	1.3	GO:0051400	BH domain binding(GO:0051400)
0.1	2.8	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.3	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
0.1	0.4	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	1.0	GO:0070330	aromatase activity(GO:0070330)
0.1	0.2	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	0.3	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	4.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.2	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.4	GO:0031432	titin binding(GO:0031432)
0.1	0.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	2.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	0.9	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	1.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.3	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.5	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.5	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.2	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.3	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.5	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0001093	TFIIB-class transcription factor binding(GO:0001093)
0.0	0.3	GO:0043426	MRF binding(GO:0043426)
0.0	0.8	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.5	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.5	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	1.0	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.2	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.5	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.0	0.1	GO:0004132	dCMP deaminase activity(GO:0004132)
0.0	0.6	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	1.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)
0.0	0.7	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	1.1	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.6	GO:0070628	proteasome binding(GO:0070628)
0.0	0.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.1	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.0	0.1	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.0	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	1.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.5	GO:0019956	chemokine binding(GO:0019956)
0.0	1.0	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.6	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	3.3	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.8	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.5	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.4	GO:0008187	poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0	0.8	GO:0030332	cyclin binding(GO:0030332)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.5	GO:0030553	cGMP binding(GO:0030553)
0.0	0.7	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.7	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.4	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.1	GO:0015250	water channel activity(GO:0015250)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.3	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0	0.2	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.4	GO:0031490	chromatin DNA binding(GO:0031490)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	19.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.5	18.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	1.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	4.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	3.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	7.8	PID BCR 5PATHWAY	BCR signaling pathway
0.1	2.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	4.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	4.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	2.9	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	2.7	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	8.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.7	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	2.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	2.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.0	PID MYC PATHWAY	C-MYC pathway
0.0	0.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.8	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	1.0	PID CXCR4 PATHWAY	CXCR4-mediated signaling events

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.6	10.9	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
2.0	6.1	GO:0070666	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
1.5	4.6	GO:0061470	T follicular helper cell differentiation(GO:0061470)
1.0	5.2	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.9	2.7	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.8	2.4	GO:0072709	cellular response to sorbitol(GO:0072709)
0.7	3.6	GO:0001834	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7	108.1	GO:0006958	complement activation, classical pathway(GO:0006958)
0.7	2.0	GO:0035284	rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.7	2.0	GO:0007412	axon target recognition(GO:0007412)
0.6	3.6	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.5	1.6	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.5	0.9	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.4	1.3	GO:1901189	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4	1.8	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.4	4.3	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4	1.4	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.3	1.0	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.3	0.3	GO:0002312	B cell activation involved in immune response(GO:0002312)
0.3	0.9	GO:0009441	glycolate metabolic process(GO:0009441)
0.3	2.1	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3	3.3	GO:0008228	opsonization(GO:0008228)
0.3	0.9	GO:0046081	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.3	1.7	GO:0070560	protein secretion by platelet(GO:0070560)
0.3	1.9	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.3	0.8	GO:1901253	negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.3	1.8	GO:0032594	protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.2	0.7	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2	0.7	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.2	1.0	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.2	0.7	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2	2.4	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2	2.7	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.2	1.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.2	0.8	GO:0036510	trimming of terminal mannose on C branch(GO:0036510)
0.2	4.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.2	1.2	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.2	0.5	GO:0014807	regulation of somitogenesis(GO:0014807)
0.2	0.7	GO:0019249	lactate biosynthetic process(GO:0019249)
0.2	0.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.2	1.8	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.2	1.7	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2	0.8	GO:0070842	aggresome assembly(GO:0070842)
0.2	0.8	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2	0.5	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2	0.5	GO:2000439	negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.2	0.5	GO:0097052	tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
0.1	0.9	GO:0016554	cytidine to uridine editing(GO:0016554) DNA deamination(GO:0045006) DNA cytosine deamination(GO:0070383)
0.1	0.7	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.7	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.5	GO:0000023	maltose metabolic process(GO:0000023)
0.1	0.5	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.8	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	0.6	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.1	0.4	GO:0048539	bone marrow development(GO:0048539)
0.1	0.6	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1	0.1	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1	0.5	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.2	GO:0097026	dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
0.1	0.8	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.1	0.3	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	0.6	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.1	0.9	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	12.2	GO:0030183	B cell differentiation(GO:0030183)
0.1	0.3	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1	0.4	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1	0.3	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.1	0.2	GO:0016321	female meiosis chromosome segregation(GO:0016321)
0.1	17.5	GO:0002377	immunoglobulin production(GO:0002377)
0.1	0.1	GO:0071902	positive regulation of protein serine/threonine kinase activity(GO:0071902)
0.1	0.3	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.1	0.8	GO:2001223	negative regulation of neuron migration(GO:2001223)
0.1	0.4	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1	0.4	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.1	7.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.3	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	0.7	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	1.0	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	1.1	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.4	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767)
0.1	3.1	GO:0072678	T cell migration(GO:0072678)
0.1	0.4	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.5	GO:0090131	mesenchyme migration(GO:0090131)
0.1	0.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.6	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	3.1	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	1.7	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.1	0.6	GO:0070166	enamel mineralization(GO:0070166)
0.1	0.4	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.2	GO:0002125	maternal aggressive behavior(GO:0002125)
0.1	0.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.1	0.3	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1	0.5	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.1	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1	0.1	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1	0.5	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.2	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1	1.7	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0019860	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.1	0.2	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.3	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	0.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1	0.7	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	1.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.3	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1	0.5	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.6	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	0.4	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.1	0.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.3	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1	0.9	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.6	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.6	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	1.0	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.9	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	1.2	GO:0009615	response to virus(GO:0009615)
0.0	0.4	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.5	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.8	GO:0030903	notochord development(GO:0030903)
0.0	0.2	GO:0036269	swimming behavior(GO:0036269)
0.0	0.1	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.0	0.7	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.5	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0	0.2	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.0	0.1	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0	0.2	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.0	GO:0061325	cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	1.1	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	1.9	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.7	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.6	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process(GO:1903052)
0.0	0.2	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.3	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.4	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	1.2	GO:0007140	male meiosis(GO:0007140)
0.0	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.7	GO:0048536	spleen development(GO:0048536)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	8.6	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.1	GO:0038163	endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0	0.6	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0061386	soft palate development(GO:0060023) closure of optic fissure(GO:0061386)
0.0	1.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:1901355	response to rapamycin(GO:1901355)
0.0	0.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0006226	dUMP biosynthetic process(GO:0006226)
0.0	0.3	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	4.0	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835) actin filament branching(GO:0090135)
0.0	0.3	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.4	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.5	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.1	GO:1902474	regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.0	0.3	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.6	GO:0036035	osteoclast development(GO:0036035)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.3	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0	0.2	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.2	GO:0051026	chiasma assembly(GO:0051026)
0.0	1.0	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0061373	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0	0.1	GO:0006597	spermine biosynthetic process(GO:0006597)
0.0	0.4	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.0	0.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0	0.2	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.1	GO:0048880	sensory system development(GO:0048880)
0.0	0.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.3	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.6	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.2	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.2	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	1.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.8	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.3	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	0.3	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
0.0	0.1	GO:0006196	AMP catabolic process(GO:0006196)
0.0	2.0	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	0.1	GO:2000334	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0	0.1	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0	0.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.7	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.1	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0	0.2	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0060067	cervix development(GO:0060067)
0.0	0.0	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.0	0.4	GO:0030728	ovulation(GO:0030728)
0.0	0.1	GO:0072660	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0	0.0	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.0	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.2	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.0	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.2	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	1.5	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.1	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.1	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.1	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.6	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.4	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.1	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.0	1.4	GO:0006275	regulation of DNA replication(GO:0006275)
0.0	0.0	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.4	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0002879	positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0	0.3	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.4	GO:0044839	G2/M transition of mitotic cell cycle(GO:0000086) cell cycle G2/M phase transition(GO:0044839)
0.0	0.2	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	18.7	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.4	10.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	13.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	2.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	4.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	3.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	3.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	3.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	3.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	2.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	7.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.7	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	2.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.7	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	2.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.0	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	5.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME SIGNALING BY NOTCH	Genes involved in Signaling by NOTCH
0.0	1.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	1.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.8	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.9	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	2.1	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
1.0	49.3	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.5	1.6	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.5	3.6	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.4	2.9	GO:0019814	immunoglobulin complex(GO:0019814)
0.4	7.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.3	4.3	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	2.1	GO:0044326	dendritic spine neck(GO:0044326)
0.3	1.3	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3	3.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.3	0.8	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1	1.1	GO:0036477	somatodendritic compartment(GO:0036477)
0.1	0.5	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.7	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.5	GO:1990031	pinceau fiber(GO:1990031)
0.1	0.1	GO:0097610	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.1	0.8	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	0.5	GO:0036398	TCR signalosome(GO:0036398)
0.1	1.0	GO:0071953	elastic fiber(GO:0071953)
0.1	0.6	GO:1990037	Lewy body core(GO:1990037)
0.1	0.6	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1	0.3	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.2	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	0.4	GO:0097149	centralspindlin complex(GO:0097149)
0.1	0.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.3	GO:0033263	CORVET complex(GO:0033263)
0.1	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.1	5.2	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.0	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	0.7	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.3	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	0.8	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.3	GO:0071546	pi-body(GO:0071546)
0.1	10.2	GO:0072562	blood microparticle(GO:0072562)
0.1	0.3	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.4	GO:0000322	storage vacuole(GO:0000322)
0.1	0.7	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.3	GO:0032009	early phagosome(GO:0032009)
0.1	0.4	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.3	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	4.3	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	1.0	GO:0071564	npBAF complex(GO:0071564)
0.0	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.4	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.6	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	3.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.7	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	7.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	1.5	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.4	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	2.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.4	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.8	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.5	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.7	GO:0005770	late endosome(GO:0005770)
0.0	0.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	1.8	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	1.7	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.6	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.4	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	4.0	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)