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ENCODE cell lines, expression (Ernst 2011)

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Results for PRDM4

Z-value: 0.65

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Transcription factors associated with PRDM4

Gene Symbol Gene ID Gene Info
PRDM4
ENSG00000110851.7 PRDM4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154925_108154945-0.116.8e-01Click!

Activity profile of PRDM4 motif

Sorted Z-values of PRDM4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_105953204 1.21 ENST00000409393.2
 CRIP1
 cysteine-rich protein 1 (intestinal)
chr14_+_105953246 1.15 ENST00000392531.3
 CRIP1
 cysteine-rich protein 1 (intestinal)
chr12_-_58240470 0.90 ENST00000548823.1
ENST00000398073.2
 CTDSP2
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr3_+_16926441 0.82 ENST00000418129.2
ENST00000396755.2
 PLCL2
 phospholipase C-like 2
chr20_+_62697564 0.81 ENST00000458442.1
 TCEA2
 transcription elongation factor A (SII), 2
chr9_-_16727978 0.80 ENST00000418777.1
ENST00000468187.2
 BNC2
 basonuclin 2
chr10_-_105212141 0.76 ENST00000369788.3
 CALHM2
 calcium homeostasis modulator 2
chr4_+_667686 0.68 ENST00000505477.1
 MYL5
 myosin, light chain 5, regulatory
chr17_+_42634844 0.67 ENST00000315323.3
 FZD2
 frizzled family receptor 2
chr22_+_38864041 0.65 ENST00000216014.4
ENST00000409006.3
 KDELR3
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr1_-_43232649 0.59 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
 LEPRE1
 leucine proline-enriched proteoglycan (leprecan) 1
chr12_+_104682496 0.56 ENST00000378070.4
 TXNRD1
 thioredoxin reductase 1
chr4_+_667307 0.55 ENST00000506838.1
 MYL5
 myosin, light chain 5, regulatory
chr3_+_148709128 0.47 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
 GYG1
 glycogenin 1
chr3_+_148709310 0.42 ENST00000484197.1
ENST00000492285.2
ENST00000461191.1
 GYG1
 glycogenin 1
chr20_-_61569296 0.41 ENST00000370371.4
 DIDO1
 death inducer-obliterator 1
chr14_+_24025194 0.35 ENST00000404535.3
ENST00000288014.6
 THTPA
 thiamine triphosphatase
chr19_-_53636125 0.32 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
 ZNF415
 zinc finger protein 415
chr7_+_143079000 0.31 ENST00000392910.2
 ZYX
 zyxin
chr10_+_123923105 0.29 ENST00000368999.1
 TACC2
 transforming, acidic coiled-coil containing protein 2
chr5_-_78281603 0.28 ENST00000264914.4
 ARSB
 arylsulfatase B
chr7_+_90893783 0.24 ENST00000287934.2
 FZD1
 frizzled family receptor 1
chr6_-_32160622 0.20 ENST00000487761.1
ENST00000375040.3
 GPSM3
 G-protein signaling modulator 3
chr1_+_172502336 0.19 ENST00000263688.3
 SUCO
 SUN domain containing ossification factor
chr7_+_143078652 0.17 ENST00000354434.4
ENST00000449423.2
 ZYX
 zyxin
chr9_+_96338647 0.16 ENST00000359246.4
 PHF2
 PHD finger protein 2
chr19_+_42724423 0.15 ENST00000301215.3
ENST00000597945.1
 ZNF526
 zinc finger protein 526
chr17_-_9929581 0.15 ENST00000437099.2
ENST00000396115.2
 GAS7
 growth arrest-specific 7
chr6_+_26045603 0.13 ENST00000540144.1
 HIST1H3C
 histone cluster 1, H3c
chr19_-_49371711 0.12 ENST00000355496.5
ENST00000263265.6
 PLEKHA4
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr1_+_43232913 0.11 ENST00000372525.5
ENST00000536543.1
 C1orf50
 chromosome 1 open reading frame 50
chr17_+_7788104 0.11 ENST00000380358.4
 CHD3
 chromodomain helicase DNA binding protein 3
chr2_+_234296792 0.11 ENST00000409813.3
 DGKD
 diacylglycerol kinase, delta 130kDa
chr19_+_50180317 0.10 ENST00000534465.1
 PRMT1
 protein arginine methyltransferase 1
chr1_+_27114589 0.10 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V
chr6_-_8064567 0.10 ENST00000543936.1
ENST00000397457.2
 BLOC1S5
 biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr2_+_219264466 0.10 ENST00000273062.2
 CTDSP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_-_61569227 0.09 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
 DIDO1
 death inducer-obliterator 1
chr5_+_102455968 0.09 ENST00000358359.3
 PPIP5K2
 diphosphoinositol pentakisphosphate kinase 2
chr1_+_27114418 0.08 ENST00000078527.4
 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V
chr5_-_180688105 0.07 ENST00000327767.4
 TRIM52
 tripartite motif containing 52
chr7_-_23571586 0.06 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
 TRA2A
 transformer 2 alpha homolog (Drosophila)
chrX_+_15808569 0.05 ENST00000380308.3
ENST00000307771.7
 ZRSR2
 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr9_-_127263265 0.05 ENST00000373587.3
 NR5A1
 nuclear receptor subfamily 5, group A, member 1
chr11_+_58910295 0.03 ENST00000420244.1
 FAM111A
 family with sequence similarity 111, member A
chr9_+_17135016 0.02 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
 CNTLN
 centlein, centrosomal protein
chr5_+_102455853 0.01 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
 PPIP5K2
 diphosphoinositol pentakisphosphate kinase 2
chr2_-_8723918 0.01 ENST00000454224.1
 AC011747.4
 AC011747.4
chr16_+_15068955 0.01 ENST00000396410.4
ENST00000569715.1
ENST00000450288.2
 PDXDC1
 pyridoxal-dependent decarboxylase domain containing 1
chr19_-_51471381 0.01 ENST00000594641.1
 KLK6
 kallikrein-related peptidase 6
chr12_+_15475331 0.01 ENST00000281171.4
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr10_+_88728189 0.00 ENST00000416348.1
 ADIRF
 adipogenesis regulatory factor
chr19_-_51471362 0.00 ENST00000376853.4
ENST00000424910.2
 KLK6
 kallikrein-related peptidase 6
chr12_+_15475462 0.00 ENST00000543886.1
ENST00000348962.2
 PTPRO
 protein tyrosine phosphatase, receptor type, O

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.3 0.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 0.9 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.4 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.8 GO:0043586 tongue development(GO:0043586)
0.0 0.3 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.6 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 2.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0089701 U2AF(GO:0089701)