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ENCODE cell lines, expression (Ernst 2011)

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Results for PTF1A

Z-value: 0.75

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
PTF1A
ENSG00000168267.5 PTF1A

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_40198527 1.91 ENST00000381799.5
 RHOH
 ras homolog family member H
chr22_+_23101182 1.74 ENST00000390312.2
 IGLV2-14
 immunoglobulin lambda variable 2-14
chr1_-_9129735 1.63 ENST00000377424.4
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr8_+_11351494 1.53 ENST00000259089.4
 BLK
 B lymphoid tyrosine kinase
chr1_-_9129598 1.40 ENST00000535586.1
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr2_-_160761179 1.24 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
 LY75
LY75-CD302
 lymphocyte antigen 75
LY75-CD302 readthrough
chr8_+_11351876 1.21 ENST00000529894.1
 BLK
 B lymphoid tyrosine kinase
chr1_-_9129895 1.13 ENST00000473209.1
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_+_7597639 1.13 ENST00000533792.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_9129631 1.07 ENST00000377414.3
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_24877490 1.03 ENST00000540914.1
ENST00000378023.4
 FAM65B
 family with sequence similarity 65, member B
chr17_+_67498538 0.98 ENST00000589647.1
 MAP2K6
 mitogen-activated protein kinase kinase 6
chr10_-_74856608 0.93 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
 P4HA1
 prolyl 4-hydroxylase, alpha polypeptide I
chr7_+_7606497 0.54 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
 MIOS
 missing oocyte, meiosis regulator, homolog (Drosophila)
chr1_+_12185949 0.52 ENST00000413146.2
 TNFRSF8
 tumor necrosis factor receptor superfamily, member 8
chr3_+_49027308 0.48 ENST00000383729.4
ENST00000343546.4
 P4HTM
 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr3_+_35721106 0.43 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr3_+_167453493 0.42 ENST00000295777.5
ENST00000472747.2
 SERPINI1
 serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr12_-_90102594 0.41 ENST00000428670.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr1_-_231114542 0.40 ENST00000522821.1
ENST00000366661.4
ENST00000366662.4
ENST00000414259.1
ENST00000522399.1
 TTC13
 tetratricopeptide repeat domain 13
chr12_+_113344755 0.40 ENST00000550883.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr3_+_35681081 0.38 ENST00000428373.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr17_+_12692774 0.38 ENST00000379672.5
ENST00000340825.3
 ARHGAP44
 Rho GTPase activating protein 44
chr11_+_96123158 0.38 ENST00000332349.4
ENST00000458427.1
 JRKL
 jerky homolog-like (mouse)
chr18_-_53177984 0.37 ENST00000543082.1
 TCF4
 transcription factor 4
chr20_+_44441215 0.37 ENST00000356455.4
ENST00000405520.1
 UBE2C
 ubiquitin-conjugating enzyme E2C
chr2_-_89513402 0.36 ENST00000498435.1
 IGKV1-27
 immunoglobulin kappa variable 1-27
chr19_-_48389651 0.35 ENST00000222002.3
 SULT2A1
 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr17_+_53342311 0.34 ENST00000226067.5
 HLF
 hepatic leukemia factor
chr20_+_44441304 0.33 ENST00000352551.5
 UBE2C
 ubiquitin-conjugating enzyme E2C
chrX_-_107019181 0.31 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
 TSC22D3
 TSC22 domain family, member 3
chr7_-_99097863 0.31 ENST00000426306.2
ENST00000337673.6
 ZNF394
 zinc finger protein 394
chr12_+_113344582 0.31 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr13_+_113633620 0.29 ENST00000421756.1
ENST00000375601.3
 MCF2L
 MCF.2 cell line derived transforming sequence-like
chr7_-_29186008 0.28 ENST00000396276.3
ENST00000265394.5
 CPVL
 carboxypeptidase, vitellogenic-like
chr5_-_118324200 0.27 ENST00000515439.3
ENST00000510708.1
 DTWD2
 DTW domain containing 2
chr12_-_48398104 0.27 ENST00000337299.6
ENST00000380518.3
 COL2A1
 collagen, type II, alpha 1
chr7_-_152373216 0.25 ENST00000359321.1
 XRCC2
 X-ray repair complementing defective repair in Chinese hamster cells 2
chr6_+_57182400 0.25 ENST00000607273.1
 PRIM2
 primase, DNA, polypeptide 2 (58kDa)
chr22_+_24999114 0.24 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
 GGT1
 gamma-glutamyltransferase 1
chr10_-_101841588 0.24 ENST00000370418.3
 CPN1
 carboxypeptidase N, polypeptide 1
chr10_-_1779663 0.22 ENST00000381312.1
 ADARB2
 adenosine deaminase, RNA-specific, B2 (non-functional)
chr5_+_169532896 0.22 ENST00000306268.6
ENST00000449804.2
 FOXI1
 forkhead box I1
chr6_-_41715128 0.22 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
 PGC
 progastricsin (pepsinogen C)
chr2_-_27435125 0.21 ENST00000414408.1
ENST00000310574.3
 SLC5A6
 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr2_+_97426631 0.21 ENST00000377075.2
 CNNM4
 cyclin M4
chr17_-_73892992 0.21 ENST00000540128.1
ENST00000269383.3
 TRIM65
 tripartite motif containing 65
chr1_-_45956822 0.20 ENST00000372086.3
ENST00000341771.6
 TESK2
 testis-specific kinase 2
chr7_-_100844193 0.20 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
 MOGAT3
 monoacylglycerol O-acyltransferase 3
chr11_-_111794446 0.20 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr15_-_89764929 0.20 ENST00000268125.5
 RLBP1
 retinaldehyde binding protein 1
chr12_+_53689309 0.19 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
 PFDN5
 prefoldin subunit 5
chr9_+_4985228 0.17 ENST00000381652.3
 JAK2
 Janus kinase 2
chr12_+_113344811 0.17 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
 OAS1
 2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr13_-_79979919 0.15 ENST00000267229.7
 RBM26
 RNA binding motif protein 26
chr2_-_89417335 0.15 ENST00000490686.1
 IGKV1-17
 immunoglobulin kappa variable 1-17
chr1_-_76076759 0.15 ENST00000370855.5
 SLC44A5
 solute carrier family 44, member 5
chr1_-_78149041 0.14 ENST00000414381.1
ENST00000370798.1
 ZZZ3
 zinc finger, ZZ-type containing 3
chrX_+_154299690 0.13 ENST00000340647.4
ENST00000330045.7
 BRCC3
 BRCA1/BRCA2-containing complex, subunit 3
chr19_-_10491234 0.13 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
 TYK2
 tyrosine kinase 2
chr17_-_33416231 0.13 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
 RFFL
 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr16_+_89696692 0.13 ENST00000261615.4
 DPEP1
 dipeptidase 1 (renal)
chr13_-_79979952 0.13 ENST00000438724.1
 RBM26
 RNA binding motif protein 26
chr17_-_3461092 0.13 ENST00000301365.4
ENST00000572519.1
 TRPV3
 transient receptor potential cation channel, subfamily V, member 3
chr16_-_75569068 0.12 ENST00000336257.3
ENST00000565039.1
 CHST5
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr1_-_45956800 0.12 ENST00000538496.1
 TESK2
 testis-specific kinase 2
chr10_-_5855350 0.12 ENST00000456041.1
ENST00000380181.3
ENST00000418688.1
ENST00000380132.4
ENST00000609712.1
ENST00000380191.4
 GDI2
 GDP dissociation inhibitor 2
chr11_-_207221 0.12 ENST00000486280.1
ENST00000332865.6
ENST00000529614.2
ENST00000325147.9
ENST00000410108.1
ENST00000382762.3
 BET1L
 Bet1 golgi vesicular membrane trafficking protein-like
chr10_+_76871454 0.12 ENST00000372687.4
 SAMD8
 sterile alpha motif domain containing 8
chr2_-_89278535 0.11 ENST00000390247.2
 IGKV3-7
 immunoglobulin kappa variable 3-7 (non-functional)
chr6_-_62996066 0.10 ENST00000281156.4
 KHDRBS2
 KH domain containing, RNA binding, signal transduction associated 2
chr17_-_42143963 0.10 ENST00000585388.1
ENST00000293406.3
 LSM12
 LSM12 homolog (S. cerevisiae)
chr2_-_136288113 0.10 ENST00000401392.1
 ZRANB3
 zinc finger, RAN-binding domain containing 3
chrX_+_154299753 0.10 ENST00000369459.2
ENST00000369462.1
ENST00000411985.1
ENST00000399042.1
 BRCC3
 BRCA1/BRCA2-containing complex, subunit 3
chr20_+_30697298 0.09 ENST00000398022.2
 TM9SF4
 transmembrane 9 superfamily protein member 4
chr5_+_140557371 0.08 ENST00000239444.2
 PCDHB8
 protocadherin beta 8
chr12_+_50451331 0.08 ENST00000228468.4
 ASIC1
 acid-sensing (proton-gated) ion channel 1
chr10_+_99332198 0.08 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
chr6_-_56258892 0.08 ENST00000370819.1
 COL21A1
 collagen, type XXI, alpha 1
chr18_+_5238549 0.07 ENST00000580684.1
 LINC00667
 long intergenic non-protein coding RNA 667
chr14_-_77737543 0.07 ENST00000298352.4
 NGB
 neuroglobin
chr12_+_112451120 0.07 ENST00000261735.3
ENST00000455836.1
 ERP29
 endoplasmic reticulum protein 29
chr17_+_40996590 0.07 ENST00000253799.3
ENST00000452774.2
 AOC2
 amine oxidase, copper containing 2 (retina-specific)
chr13_+_113812956 0.06 ENST00000375547.2
ENST00000342783.4
 PROZ
 protein Z, vitamin K-dependent plasma glycoprotein
chr13_+_49794474 0.06 ENST00000218721.1
ENST00000398307.1
 MLNR
 motilin receptor
chrX_+_155110956 0.05 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
 VAMP7
 vesicle-associated membrane protein 7
chr3_+_51663407 0.05 ENST00000432863.1
ENST00000296477.3
 RAD54L2
 RAD54-like 2 (S. cerevisiae)
chr10_+_43572475 0.05 ENST00000355710.3
ENST00000498820.1
ENST00000340058.5
 RET
 ret proto-oncogene
chr16_-_15950868 0.05 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
 MYH11
 myosin, heavy chain 11, smooth muscle
chr16_+_2802316 0.05 ENST00000301740.8
 SRRM2
 serine/arginine repetitive matrix 2
chr3_+_40518599 0.05 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
 ZNF619
 zinc finger protein 619
chrX_+_15808569 0.05 ENST00000380308.3
ENST00000307771.7
 ZRSR2
 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr20_-_48732472 0.04 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
 UBE2V1
 ubiquitin-conjugating enzyme E2 variant 1
chr12_+_75784850 0.04 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
 GLIPR1L2
 GLI pathogenesis-related 1 like 2
chr6_+_27107053 0.04 ENST00000354348.2
 HIST1H4I
 histone cluster 1, H4i
chr18_+_33877654 0.04 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
 FHOD3
 formin homology 2 domain containing 3
chr8_-_22089533 0.04 ENST00000321613.3
 PHYHIP
 phytanoyl-CoA 2-hydroxylase interacting protein
chr15_+_68924327 0.04 ENST00000543950.1
 CORO2B
 coronin, actin binding protein, 2B
chr22_-_17640110 0.04 ENST00000399852.3
ENST00000336737.4
 CECR5
 cat eye syndrome chromosome region, candidate 5
chr4_+_156588115 0.04 ENST00000455639.2
 GUCY1A3
 guanylate cyclase 1, soluble, alpha 3
chr22_-_50523760 0.04 ENST00000395876.2
 MLC1
 megalencephalic leukoencephalopathy with subcortical cysts 1
chr12_+_12966250 0.03 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
 DDX47
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr4_-_83719884 0.03 ENST00000282709.4
ENST00000273908.4
 SCD5
 stearoyl-CoA desaturase 5
chr4_-_89744314 0.03 ENST00000508369.1
 FAM13A
 family with sequence similarity 13, member A
chr19_-_40331345 0.03 ENST00000597224.1
 FBL
 fibrillarin
chr4_-_89744365 0.03 ENST00000513837.1
ENST00000503556.1
 FAM13A
 family with sequence similarity 13, member A
chr12_+_120884222 0.03 ENST00000551765.1
ENST00000229384.5
 GATC
 glutamyl-tRNA(Gln) amidotransferase, subunit C
chr21_+_44073916 0.03 ENST00000349112.3
ENST00000398224.3
 PDE9A
 phosphodiesterase 9A
chr21_+_44073860 0.03 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
 PDE9A
 phosphodiesterase 9A
chr16_-_46723066 0.02 ENST00000299138.7
 VPS35
 vacuolar protein sorting 35 homolog (S. cerevisiae)
chr4_-_175750364 0.02 ENST00000340217.5
ENST00000274093.3
 GLRA3
 glycine receptor, alpha 3
chr11_+_71238313 0.02 ENST00000398536.4
 KRTAP5-7
 keratin associated protein 5-7
chr13_+_49280951 0.01 ENST00000282018.3
 CYSLTR2
 cysteinyl leukotriene receptor 2
chr19_+_45254529 0.00 ENST00000444487.1
 BCL3
 B-cell CLL/lymphoma 3
chr4_-_123843597 0.00 ENST00000510735.1
ENST00000304430.5
 NUDT6
 nudix (nucleoside diphosphate linked moiety X)-type motif 6

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.2 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.3 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.5 GO:0032639 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.7 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 2.7 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 1.9 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0007497 posterior midgut development(GO:0007497)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.9 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.2 0.9 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 3.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 5.1 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 3.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0043596 nuclear replication fork(GO:0043596)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling