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ENCODE cell lines, expression (Ernst 2011)

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Results for RAD21_SMC3

Z-value: 0.90

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Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
RAD21
ENSG00000164754.8 RAD21
SMC3
ENSG00000108055.9 SMC3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMC3hg19_v2_chr10_+_112327425_112327516-0.371.5e-01Click!
RAD21hg19_v2_chr8_-_117886955_117887105-0.039.2e-01Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_+_17272608 3.45 ENST00000421459.2
 VIM
 vimentin
chr19_-_55653259 2.31 ENST00000593194.1
 TNNT1
 troponin T type 1 (skeletal, slow)
chr19_-_55652290 2.29 ENST00000589745.1
 TNNT1
 troponin T type 1 (skeletal, slow)
chr15_-_58358607 2.12 ENST00000249750.4
 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
chr22_-_22901477 2.10 ENST00000420709.1
ENST00000398741.1
ENST00000405655.3
 PRAME
 preferentially expressed antigen in melanoma
chr22_-_22901636 2.07 ENST00000406503.1
ENST00000439106.1
ENST00000402697.1
ENST00000543184.1
ENST00000398743.2
 PRAME
 preferentially expressed antigen in melanoma
chr5_-_136834982 1.99 ENST00000510689.1
ENST00000394945.1
 SPOCK1
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr7_-_22539771 1.55 ENST00000406890.2
ENST00000424363.1
 STEAP1B
 STEAP family member 1B
chr22_-_22292934 1.52 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
 PPM1F
 protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr16_+_2867228 1.27 ENST00000005995.3
ENST00000574813.1
 PRSS21
 protease, serine, 21 (testisin)
chr2_+_69240511 1.24 ENST00000409349.3
 ANTXR1
 anthrax toxin receptor 1
chr10_-_49732281 1.23 ENST00000374170.1
 ARHGAP22
 Rho GTPase activating protein 22
chr16_+_2867164 1.22 ENST00000455114.1
ENST00000450020.3
 PRSS21
 protease, serine, 21 (testisin)
chr1_+_145524891 1.21 ENST00000369304.3
 ITGA10
 integrin, alpha 10
chr2_+_69240415 1.20 ENST00000409829.3
 ANTXR1
 anthrax toxin receptor 1
chr12_-_51663728 1.19 ENST00000603864.1
ENST00000605426.1
 SMAGP
 small cell adhesion glycoprotein
chr15_+_63340734 1.18 ENST00000560959.1
 TPM1
 tropomyosin 1 (alpha)
chr2_+_69240302 1.18 ENST00000303714.4
 ANTXR1
 anthrax toxin receptor 1
chr14_-_75079026 1.16 ENST00000261978.4
 LTBP2
 latent transforming growth factor beta binding protein 2
chr1_-_170043709 1.13 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
 KIFAP3
 kinesin-associated protein 3
chr11_-_407103 1.13 ENST00000526395.1
 SIGIRR
 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr15_+_63340553 1.09 ENST00000334895.5
 TPM1
 tropomyosin 1 (alpha)
chr1_-_6614565 1.09 ENST00000377705.5
 NOL9
 nucleolar protein 9
chr12_-_51663959 1.08 ENST00000604188.1
ENST00000398453.3
 SMAGP
 small cell adhesion glycoprotein
chr11_-_130786400 1.07 ENST00000265909.4
 SNX19
 sorting nexin 19
chr15_+_63340775 1.07 ENST00000559281.1
ENST00000317516.7
 TPM1
 tropomyosin 1 (alpha)
chr1_+_10490779 1.05 ENST00000477755.1
 APITD1
 apoptosis-inducing, TAF9-like domain 1
chr8_-_90996837 1.03 ENST00000519426.1
ENST00000265433.3
 NBN
 nibrin
chr13_-_88323218 1.03 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
 MIR4500HG
 MIR4500 host gene (non-protein coding)
chr3_-_128212016 1.02 ENST00000498200.1
ENST00000341105.2
 GATA2
 GATA binding protein 2
chr22_-_22307199 0.99 ENST00000397495.4
ENST00000263212.5
 PPM1F
 protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr16_-_19897455 0.93 ENST00000568214.1
ENST00000569479.1
 GPRC5B
 G protein-coupled receptor, family C, group 5, member B
chr12_+_111843749 0.91 ENST00000341259.2
 SH2B3
 SH2B adaptor protein 3
chr16_-_2390704 0.90 ENST00000301732.5
ENST00000382381.3
 ABCA3
 ATP-binding cassette, sub-family A (ABC1), member 3
chr7_-_27219849 0.88 ENST00000396344.4
 HOXA10
 homeobox A10
chr1_-_94374946 0.87 ENST00000370238.3
 GCLM
 glutamate-cysteine ligase, modifier subunit
chr16_+_230435 0.85 ENST00000199708.2
 HBQ1
 hemoglobin, theta 1
chr8_-_90996459 0.85 ENST00000517337.1
ENST00000409330.1
 NBN
 nibrin
chr1_-_113249734 0.84 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
 RHOC
 ras homolog family member C
chr22_+_19705928 0.83 ENST00000383045.3
ENST00000438754.2
 SEPT5
 septin 5
chr1_-_113249678 0.83 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
 RHOC
 ras homolog family member C
chr1_+_186344883 0.81 ENST00000367470.3
 C1orf27
 chromosome 1 open reading frame 27
chr11_-_113644491 0.80 ENST00000200135.3
 ZW10
 zw10 kinetochore protein
chr19_+_48216600 0.76 ENST00000263277.3
ENST00000538399.1
 EHD2
 EH-domain containing 2
chr1_+_186344945 0.76 ENST00000419367.3
ENST00000287859.6
 C1orf27
 chromosome 1 open reading frame 27
chr1_+_193091080 0.76 ENST00000367435.3
 CDC73
 cell division cycle 73
chr10_-_76868931 0.75 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
 DUSP13
 dual specificity phosphatase 13
chr1_+_151129135 0.75 ENST00000602841.1
 SCNM1
 sodium channel modifier 1
chr3_+_58291965 0.73 ENST00000445193.3
ENST00000295959.5
ENST00000466547.1
 RPP14
 ribonuclease P/MRP 14kDa subunit
chr19_+_41313017 0.69 ENST00000595621.1
ENST00000595051.1
 EGLN2
 egl-9 family hypoxia-inducible factor 2
chr15_+_63340647 0.69 ENST00000404484.4
 TPM1
 tropomyosin 1 (alpha)
chr8_-_77912431 0.66 ENST00000357039.4
ENST00000522527.1
 PEX2
 peroxisomal biogenesis factor 2
chr1_+_95699704 0.65 ENST00000370202.4
 RWDD3
 RWD domain containing 3
chr10_+_35416223 0.65 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
 CREM
 cAMP responsive element modulator
chr7_-_5569588 0.63 ENST00000417101.1
 ACTB
 actin, beta
chr2_+_231921574 0.62 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
 PSMD1
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr12_+_58176525 0.61 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
 TSFM
 Ts translation elongation factor, mitochondrial
chr11_-_61647935 0.61 ENST00000531956.1
 FADS3
 fatty acid desaturase 3
chr12_+_123237321 0.60 ENST00000280557.6
ENST00000455982.2
 DENR
 density-regulated protein
chr16_-_30032610 0.60 ENST00000574405.1
 DOC2A
 double C2-like domains, alpha
chr6_+_127588020 0.60 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
 RNF146
 ring finger protein 146
chr9_+_91003271 0.60 ENST00000375859.3
ENST00000541629.1
 SPIN1
 spindlin 1
chr9_-_94712434 0.58 ENST00000375708.3
 ROR2
 receptor tyrosine kinase-like orphan receptor 2
chr9_+_130965677 0.54 ENST00000393594.3
ENST00000486160.1
 DNM1
 dynamin 1
chr9_+_130965651 0.54 ENST00000475805.1
ENST00000341179.7
ENST00000372923.3
 DNM1
 dynamin 1
chr10_-_27149792 0.54 ENST00000376140.3
ENST00000376170.4
 ABI1
 abl-interactor 1
chr1_-_36615051 0.54 ENST00000373163.1
 TRAPPC3
 trafficking protein particle complex 3
chrX_+_110924346 0.54 ENST00000371979.3
ENST00000251943.4
ENST00000486353.1
ENST00000394780.3
ENST00000495283.1
 ALG13
 ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr19_+_49496705 0.53 ENST00000595090.1
 RUVBL2
 RuvB-like AAA ATPase 2
chr1_-_36615065 0.53 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
 TRAPPC3
 trafficking protein particle complex 3
chr19_+_49496782 0.52 ENST00000601968.1
ENST00000596837.1
 RUVBL2
 RuvB-like AAA ATPase 2
chr1_+_203830703 0.52 ENST00000414487.2
 SNRPE
 small nuclear ribonucleoprotein polypeptide E
chr3_-_183735731 0.52 ENST00000334444.6
 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr1_+_21835858 0.52 ENST00000539907.1
ENST00000540617.1
ENST00000374840.3
 ALPL
 alkaline phosphatase, liver/bone/kidney
chr16_+_2255841 0.52 ENST00000301725.7
 MLST8
 MTOR associated protein, LST8 homolog (S. cerevisiae)
chr9_-_139940608 0.52 ENST00000371601.4
 NPDC1
 neural proliferation, differentiation and control, 1
chr11_-_36531774 0.51 ENST00000348124.5
ENST00000526995.1
 TRAF6
 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
chr10_-_6622258 0.49 ENST00000263125.5
 PRKCQ
 protein kinase C, theta
chr16_-_30441293 0.48 ENST00000565758.1
ENST00000567983.1
ENST00000319285.4
 DCTPP1
 dCTP pyrophosphatase 1
chrX_+_149009941 0.48 ENST00000535454.1
ENST00000542674.1
ENST00000286482.1
 MAGEA8
 melanoma antigen family A, 8
chrX_+_11776701 0.48 ENST00000476743.1
ENST00000421368.2
ENST00000398527.2
 MSL3
 male-specific lethal 3 homolog (Drosophila)
chr19_+_45842445 0.48 ENST00000598357.1
 L47234.1
 Uncharacterized protein
chr10_-_6622201 0.48 ENST00000539722.1
ENST00000397176.2
 PRKCQ
 protein kinase C, theta
chr11_-_63536113 0.47 ENST00000433688.1
ENST00000546282.2
 C11orf95
RP11-466C23.4
 chromosome 11 open reading frame 95
RP11-466C23.4
chr10_+_13628933 0.47 ENST00000417658.1
ENST00000320054.4
 PRPF18
 pre-mRNA processing factor 18
chr6_+_127587755 0.47 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
 RNF146
 ring finger protein 146
chr16_+_2255710 0.46 ENST00000397124.1
ENST00000565250.1
 MLST8
 MTOR associated protein, LST8 homolog (S. cerevisiae)
chr5_-_146833485 0.46 ENST00000398514.3
 DPYSL3
 dihydropyrimidinase-like 3
chr11_-_64510409 0.45 ENST00000394429.1
ENST00000394428.1
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_22034770 0.44 ENST00000598381.1
 ZNF43
 zinc finger protein 43
chr3_-_64009102 0.44 ENST00000478185.1
ENST00000482510.1
ENST00000497323.1
ENST00000492933.1
ENST00000295901.4
 PSMD6
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr9_+_139560197 0.43 ENST00000371698.3
 EGFL7
 EGF-like-domain, multiple 7
chr10_-_6019984 0.43 ENST00000525219.2
 IL15RA
 interleukin 15 receptor, alpha
chr17_-_79827808 0.42 ENST00000580685.1
 ARHGDIA
 Rho GDP dissociation inhibitor (GDI) alpha
chr10_-_27149851 0.42 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
 ABI1
 abl-interactor 1
chr12_-_56583332 0.42 ENST00000347471.4
ENST00000267064.4
ENST00000394023.3
 SMARCC2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr10_+_13628921 0.41 ENST00000378572.3
 PRPF18
 pre-mRNA processing factor 18
chr19_-_41859814 0.41 ENST00000221930.5
 TGFB1
 transforming growth factor, beta 1
chrX_+_11776410 0.41 ENST00000361672.2
 MSL3
 male-specific lethal 3 homolog (Drosophila)
chr19_-_22034809 0.41 ENST00000594012.1
ENST00000595461.1
ENST00000596899.1
 ZNF43
 zinc finger protein 43
chr15_-_34502278 0.39 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
 KATNBL1
 katanin p80 subunit B-like 1
chr1_+_10270863 0.39 ENST00000377093.4
ENST00000263934.6
 KIF1B
 kinesin family member 1B
chr14_+_100259666 0.39 ENST00000262233.6
ENST00000334192.4
 EML1
 echinoderm microtubule associated protein like 1
chr19_-_14682838 0.39 ENST00000215565.2
 NDUFB7
 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
chr5_+_172571445 0.39 ENST00000231668.9
ENST00000351486.5
ENST00000352523.6
ENST00000393770.4
 BNIP1
 BCL2/adenovirus E1B 19kDa interacting protein 1
chr3_-_64009658 0.38 ENST00000394431.2
 PSMD6
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr9_+_100263912 0.38 ENST00000259365.4
 TMOD1
 tropomodulin 1
chrX_+_77166172 0.37 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr17_-_34890732 0.37 ENST00000268852.9
 MYO19
 myosin XIX
chr1_+_29063119 0.37 ENST00000474884.1
ENST00000542507.1
 YTHDF2
 YTH domain family, member 2
chr17_-_3749515 0.37 ENST00000158149.3
ENST00000389005.4
 C17orf85
 chromosome 17 open reading frame 85
chr2_-_24307162 0.36 ENST00000413037.1
ENST00000407482.1
 TP53I3
 tumor protein p53 inducible protein 3
chr3_+_5163905 0.36 ENST00000256496.3
ENST00000419534.2
 ARL8B
 ADP-ribosylation factor-like 8B
chr1_-_113249948 0.36 ENST00000339083.7
ENST00000369642.3
 RHOC
 ras homolog family member C
chr1_+_10490127 0.36 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
 APITD1
APITD1-CORT
 apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr1_+_95699740 0.36 ENST00000429514.2
ENST00000263893.6
 RWDD3
 RWD domain containing 3
chr1_-_172413226 0.36 ENST00000367728.1
ENST00000258324.1
 PIGC
 phosphatidylinositol glycan anchor biosynthesis, class C
chr1_+_36348790 0.36 ENST00000373204.4
 AGO1
 argonaute RISC catalytic component 1
chr8_+_38758737 0.35 ENST00000521746.1
ENST00000420274.1
 PLEKHA2
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr13_-_37573432 0.35 ENST00000413537.2
ENST00000443765.1
ENST00000239891.3
 ALG5
 ALG5, dolichyl-phosphate beta-glucosyltransferase
chr8_-_74659068 0.35 ENST00000523558.1
ENST00000521210.1
ENST00000355780.5
ENST00000524104.1
ENST00000521736.1
ENST00000521447.1
ENST00000517542.1
ENST00000521451.1
ENST00000521419.1
ENST00000518502.1
ENST00000524300.1
 STAU2
 staufen double-stranded RNA binding protein 2
chr1_-_202129704 0.35 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
 PTPN7
 protein tyrosine phosphatase, non-receptor type 7
chr17_-_33469299 0.35 ENST00000586869.1
ENST00000360831.5
ENST00000442241.4
 NLE1
 notchless homolog 1 (Drosophila)
chr12_-_56583243 0.35 ENST00000550164.1
 SMARCC2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr1_+_10490441 0.34 ENST00000470413.2
ENST00000309048.3
 APITD1-CORT
APITD1
 APITD1-CORT readthrough
apoptosis-inducing, TAF9-like domain 1
chr10_-_27149904 0.34 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
 ABI1
 abl-interactor 1
chr5_+_148521381 0.34 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr19_-_19051927 0.34 ENST00000600077.1
 HOMER3
 homer homolog 3 (Drosophila)
chr16_-_66864806 0.34 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
 NAE1
 NEDD8 activating enzyme E1 subunit 1
chr1_-_172413195 0.34 ENST00000344529.4
 PIGC
 phosphatidylinositol glycan anchor biosynthesis, class C
chr5_-_176889381 0.34 ENST00000393563.4
ENST00000512501.1
 DBN1
 drebrin 1
chr10_+_35416090 0.34 ENST00000354759.3
 CREM
 cAMP responsive element modulator
chr1_-_226595741 0.34 ENST00000366794.5
ENST00000366792.1
ENST00000366791.5
 PARP1
 poly (ADP-ribose) polymerase 1
chr5_+_148521046 0.34 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
 ABLIM3
 actin binding LIM protein family, member 3
chr10_+_13203543 0.33 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
 MCM10
 minichromosome maintenance complex component 10
chr17_-_33446820 0.33 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
 RAD51D
 RAD51 paralog D
chr11_-_117103208 0.33 ENST00000320934.3
ENST00000530269.1
 PCSK7
 proprotein convertase subtilisin/kexin type 7
chr2_-_128399706 0.32 ENST00000426981.1
 LIMS2
 LIM and senescent cell antigen-like domains 2
chr17_-_26220366 0.32 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
 LYRM9
RP1-66C13.4
 LYR motif containing 9
Uncharacterized protein
chr10_+_31610064 0.32 ENST00000446923.2
ENST00000559476.1
 ZEB1
 zinc finger E-box binding homeobox 1
chr5_+_34656569 0.32 ENST00000428746.2
 RAI14
 retinoic acid induced 14
chr16_-_67514982 0.32 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
 ATP6V0D1
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr19_+_24216213 0.32 ENST00000594934.1
ENST00000597683.1
ENST00000342944.6
 CTD-2017D11.1
ZNF254
 CTD-2017D11.1
zinc finger protein 254
chr5_+_34656331 0.32 ENST00000265109.3
 RAI14
 retinoic acid induced 14
chr17_+_16318850 0.32 ENST00000338560.7
 TRPV2
 transient receptor potential cation channel, subfamily V, member 2
chr17_+_16318909 0.31 ENST00000577397.1
 TRPV2
 transient receptor potential cation channel, subfamily V, member 2
chr15_-_35261996 0.31 ENST00000156471.5
 AQR
 aquarius intron-binding spliceosomal factor
chr4_+_71570430 0.30 ENST00000417478.2
 RUFY3
 RUN and FYVE domain containing 3
chr3_-_183602515 0.30 ENST00000449306.1
ENST00000435888.1
ENST00000311101.5
ENST00000317096.4
 PARL
 presenilin associated, rhomboid-like
chr14_-_50319482 0.30 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
 NEMF
 nuclear export mediator factor
chr12_-_96794143 0.30 ENST00000543119.2
 CDK17
 cyclin-dependent kinase 17
chr21_-_34852304 0.30 ENST00000542230.2
 TMEM50B
 transmembrane protein 50B
chr2_-_24307635 0.30 ENST00000313482.4
 TP53I3
 tumor protein p53 inducible protein 3
chr10_+_35415719 0.30 ENST00000474362.1
ENST00000374721.3
 CREM
 cAMP responsive element modulator
chr1_-_40367668 0.29 ENST00000397332.2
ENST00000429311.1
 MYCL
 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chrX_+_153029633 0.29 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
 PLXNB3
 plexin B3
chr17_+_7621045 0.29 ENST00000570791.1
 DNAH2
 dynein, axonemal, heavy chain 2
chr7_-_99679324 0.29 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
 ZNF3
 zinc finger protein 3
chr17_+_61562178 0.28 ENST00000490216.2
 ACE
 angiotensin I converting enzyme
chr5_+_148521136 0.28 ENST00000506113.1
 ABLIM3
 actin binding LIM protein family, member 3
chr12_+_104609550 0.28 ENST00000525566.1
ENST00000429002.2
 TXNRD1
 thioredoxin reductase 1
chr3_-_8811288 0.27 ENST00000316793.3
ENST00000431493.1
 OXTR
 oxytocin receptor
chr10_+_99332529 0.27 ENST00000455090.1
 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
chr10_+_99332198 0.27 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
chr11_-_64511575 0.27 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_61523622 0.27 ENST00000448884.2
ENST00000582297.1
ENST00000582034.1
ENST00000578072.1
ENST00000360793.3
 CYB561
 cytochrome b561
chr12_+_56618102 0.27 ENST00000267023.4
ENST00000380198.2
ENST00000341463.5
 NABP2
 nucleic acid binding protein 2
chr12_+_51985001 0.27 ENST00000354534.6
 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
chr17_-_33446735 0.26 ENST00000460118.2
ENST00000335858.7
 RAD51D
 RAD51 paralog D
chr1_+_154244987 0.26 ENST00000328703.7
ENST00000457918.2
ENST00000483970.2
ENST00000435087.1
ENST00000532105.1
 HAX1
 HCLS1 associated protein X-1
chr10_+_35415978 0.26 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
 CREM
 cAMP responsive element modulator
chr14_+_22446680 0.26 ENST00000390443.3
 TRAV8-6
 T cell receptor alpha variable 8-6
chr1_+_29063271 0.25 ENST00000373812.3
 YTHDF2
 YTH domain family, member 2
chr1_+_28844778 0.25 ENST00000411533.1
 RCC1
 regulator of chromosome condensation 1
chr11_+_107879459 0.25 ENST00000393094.2
 CUL5
 cullin 5
chr22_-_32808194 0.25 ENST00000451746.2
ENST00000216038.5
 RTCB
 RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr12_-_96794330 0.25 ENST00000261211.3
 CDK17
 cyclin-dependent kinase 17
chr3_-_108836977 0.25 ENST00000232603.5
 MORC1
 MORC family CW-type zinc finger 1
chr20_-_30311703 0.25 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
 BCL2L1
 BCL2-like 1
chr5_-_179050066 0.25 ENST00000329433.6
ENST00000510411.1
 HNRNPH1
 heterogeneous nuclear ribonucleoprotein H1 (H)
chr12_-_56709786 0.25 ENST00000547423.1
ENST00000548360.1
ENST00000551475.1
 RP11-977G19.10
CNPY2
 Uncharacterized protein
canopy FGF signaling regulator 2
chr19_-_49496557 0.25 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
 GYS1
 glycogen synthase 1 (muscle)
chr7_-_19748640 0.25 ENST00000222567.5
 TWISTNB
 TWIST neighbor
chr12_-_56709674 0.25 ENST00000551286.1
ENST00000549318.1
 CNPY2
RP11-977G19.10
 canopy FGF signaling regulator 2
Uncharacterized protein
chr16_-_47177874 0.25 ENST00000562435.1
 NETO2
 neuropilin (NRP) and tolloid (TLL)-like 2
chr11_+_20409070 0.24 ENST00000331079.6
 PRMT3
 protein arginine methyltransferase 3
chr5_-_146833222 0.24 ENST00000534907.1
 DPYSL3
 dihydropyrimidinase-like 3
chr11_-_66206260 0.23 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
 MRPL11
 mitochondrial ribosomal protein L11
chr9_-_123239632 0.23 ENST00000416449.1
 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
chr11_+_64948665 0.23 ENST00000533820.1
 CAPN1
 calpain 1, (mu/I) large subunit
chr17_+_61562201 0.23 ENST00000290863.6
ENST00000413513.3
ENST00000421982.2
 ACE
 angiotensin I converting enzyme
chr1_+_29063439 0.23 ENST00000541996.1
ENST00000496288.1
 YTHDF2
 YTH domain family, member 2
chr11_+_46368956 0.23 ENST00000543978.1
 DGKZ
 diacylglycerol kinase, zeta
chr17_+_63133587 0.23 ENST00000449996.3
ENST00000262406.9
 RGS9
 regulator of G-protein signaling 9
chr19_-_49149553 0.23 ENST00000084798.4
 CA11
 carbonic anhydrase XI
chr7_-_38407770 0.22 ENST00000390348.2
 TRGV1
 T cell receptor gamma variable 1 (non-functional)
chr10_-_96122682 0.22 ENST00000371361.3
 NOC3L
 nucleolar complex associated 3 homolog (S. cerevisiae)
chr5_-_139726181 0.22 ENST00000507104.1
ENST00000230990.6
 HBEGF
 heparin-binding EGF-like growth factor
chr17_-_34890759 0.22 ENST00000431794.3
 MYO19
 myosin XIX
chr14_-_102701740 0.22 ENST00000561150.1
ENST00000522867.1
 MOK
 MOK protein kinase

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 2.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.3 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.3 0.9 GO:0071020 post-spliceosomal complex(GO:0071020)
0.3 1.1 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.3 1.9 GO:0030870 Mre11 complex(GO:0030870)
0.3 0.8 GO:0070939 Dsl1p complex(GO:0070939)
0.2 4.0 GO:0032059 bleb(GO:0032059)
0.2 4.6 GO:0005861 troponin complex(GO:0005861)
0.2 1.1 GO:0072487 MSL complex(GO:0072487)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.5 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 3.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.1 GO:0097255 R2TP complex(GO:0097255)
0.1 0.6 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0034455 t-UTP complex(GO:0034455)
0.1 1.1 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 2.1 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 2.2 GO:0032420 stereocilium(GO:0032420)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.7 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 1.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 3.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.0 GO:0097149 centralspindlin complex(GO:0097149)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0000791 euchromatin(GO:0000791)
0.0 1.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0045178 basal part of cell(GO:0045178)
0.0 0.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:1990254 keratin filament binding(GO:1990254)
0.3 4.6 GO:0031014 troponin T binding(GO:0031014)
0.3 1.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.9 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 2.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 2.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 1.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.3 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 4.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 0.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 4.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 3.5 GO:0005518 collagen binding(GO:0005518)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.0 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.3 GO:0098505 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.2 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.9 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.5 4.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5 2.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.5 4.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 1.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.4 1.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.4 1.1 GO:1990502 dense core granule maturation(GO:1990502)
0.4 1.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3 1.0 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.3 2.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 1.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.3 3.6 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.3 4.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 0.9 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.3 2.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.2 1.0 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.2 1.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 2.1 GO:0035799 ureter maturation(GO:0035799)
0.2 0.9 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.2 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.5 GO:0071529 cementum mineralization(GO:0071529)
0.2 1.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.6 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:0052510 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.4 GO:1904647 response to rotenone(GO:1904647)
0.1 0.5 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.9 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.6 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.8 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.5 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 1.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.9 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 1.3 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.7 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 0.8 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 0.3 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.1 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.0 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.4 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 1.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 2.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.7 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 1.1 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.4 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 1.9 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1901889 negative regulation of cell junction assembly(GO:1901889)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.8 GO:0097435 fibril organization(GO:0097435)
0.0 0.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.0 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.7 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.8 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 1.5 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 1.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 3.4 PID AURORA B PATHWAY Aurora B signaling
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 PID EPO PATHWAY EPO signaling pathway
0.0 1.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling