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ENCODE cell lines, expression (Ernst 2011)

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Results for RBPJ

Z-value: 0.59

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Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
RBPJ
ENSG00000168214.16 RBPJ

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RBPJhg19_v2_chr4_+_26321284_26321377,
hg19_v2_chr4_+_26322409_26322479		0.146.2e-01Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_70719925 0.86 ENST00000338779.6
 MTSS1L
 metastasis suppressor 1-like
chr9_+_706842 0.74 ENST00000382293.3
 KANK1
 KN motif and ankyrin repeat domains 1
chr10_+_124320156 0.74 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
 DMBT1
 deleted in malignant brain tumors 1
chr1_-_146644036 0.72 ENST00000425272.2
 PRKAB2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr10_+_124320195 0.72 ENST00000359586.6
 DMBT1
 deleted in malignant brain tumors 1
chr8_-_80680078 0.71 ENST00000337919.5
ENST00000354724.3
 HEY1
 hes-related family bHLH transcription factor with YRPW motif 1
chr7_+_102553430 0.68 ENST00000339431.4
ENST00000249377.4
 LRRC17
 leucine rich repeat containing 17
chrX_+_152907913 0.67 ENST00000370167.4
 DUSP9
 dual specificity phosphatase 9
chr1_-_146644122 0.64 ENST00000254101.3
 PRKAB2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr14_-_53417732 0.54 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
 FERMT2
 fermitin family member 2
chr12_-_90049878 0.52 ENST00000359142.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr16_+_85645007 0.51 ENST00000405402.2
 GSE1
 Gse1 coiled-coil protein
chr15_+_74218787 0.48 ENST00000261921.7
 LOXL1
 lysyl oxidase-like 1
chr12_-_90049828 0.47 ENST00000261173.2
ENST00000348959.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr7_+_55177416 0.47 ENST00000450046.1
ENST00000454757.2
 EGFR
 epidermal growth factor receptor
chr3_+_38017264 0.44 ENST00000436654.1
 CTDSPL
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr11_+_112832202 0.44 ENST00000534015.1
 NCAM1
 neural cell adhesion molecule 1
chr10_+_31608054 0.38 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
 ZEB1
 zinc finger E-box binding homeobox 1
chr17_+_2699697 0.38 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
 RAP1GAP2
 RAP1 GTPase activating protein 2
chr10_-_51371321 0.35 ENST00000602930.1
 AGAP8
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
chr11_+_112832133 0.35 ENST00000524665.1
 NCAM1
 neural cell adhesion molecule 1
chr17_-_36891830 0.33 ENST00000578487.1
 PCGF2
 polycomb group ring finger 2
chr2_+_3642545 0.32 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
 COLEC11
 collectin sub-family member 11
chr17_+_73452545 0.31 ENST00000314256.7
 KIAA0195
 KIAA0195
chr18_+_3451584 0.29 ENST00000551541.1
 TGIF1
 TGFB-induced factor homeobox 1
chrX_+_123094369 0.28 ENST00000455404.1
ENST00000218089.9
 STAG2
 stromal antigen 2
chr3_+_142442841 0.28 ENST00000476941.1
ENST00000273482.6
 TRPC1
 transient receptor potential cation channel, subfamily C, member 1
chr7_-_22259845 0.28 ENST00000420196.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr22_+_20861858 0.27 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
 MED15
 mediator complex subunit 15
chr16_-_53737795 0.26 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
 RPGRIP1L
 RPGRIP1-like
chr16_-_53737722 0.26 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
 RPGRIP1L
 RPGRIP1-like
chr11_+_112832090 0.25 ENST00000533760.1
 NCAM1
 neural cell adhesion molecule 1
chr15_+_40697988 0.23 ENST00000487418.2
ENST00000479013.2
 IVD
 isovaleryl-CoA dehydrogenase
chr17_+_38474489 0.23 ENST00000394089.2
ENST00000425707.3
 RARA
 retinoic acid receptor, alpha
chr1_+_15272271 0.22 ENST00000400797.3
 KAZN
 kazrin, periplakin interacting protein
chr4_-_164534657 0.22 ENST00000339875.5
 MARCH1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_27169801 0.21 ENST00000511914.1
 HOXA4
 homeobox A4
chrX_+_106045891 0.21 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
 TBC1D8B
 TBC1 domain family, member 8B (with GRAM domain)
chr17_+_41322483 0.20 ENST00000341165.6
ENST00000586650.1
ENST00000422280.1
 NBR1
 neighbor of BRCA1 gene 1
chr16_-_57831676 0.20 ENST00000465878.2
ENST00000539578.1
ENST00000561524.1
 KIFC3
 kinesin family member C3
chr19_+_56652556 0.20 ENST00000337080.3
 ZNF444
 zinc finger protein 444
chr19_+_56652686 0.19 ENST00000592949.1
 ZNF444
 zinc finger protein 444
chr12_-_16759711 0.19 ENST00000447609.1
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr16_-_57836321 0.19 ENST00000569112.1
ENST00000562311.1
ENST00000445690.2
ENST00000379655.4
 KIFC3
 kinesin family member C3
chr19_-_39390440 0.17 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2
 sirtuin 2
chr19_-_39390350 0.16 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2
 sirtuin 2
chrX_+_19362011 0.16 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
 PDHA1
 pyruvate dehydrogenase (lipoamide) alpha 1
chr9_-_35665165 0.15 ENST00000343259.3
ENST00000378387.3
 ARHGEF39
 Rho guanine nucleotide exchange factor (GEF) 39
chr6_+_30297306 0.15 ENST00000420746.1
ENST00000513556.1
 TRIM39
TRIM39-RPP21
 tripartite motif containing 39
TRIM39-RPP21 readthrough
chr3_-_183735731 0.15 ENST00000334444.6
 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_+_24701628 0.14 ENST00000355299.4
ENST00000559836.1
 GMPR2
 guanosine monophosphate reductase 2
chr2_-_219134822 0.14 ENST00000444053.1
ENST00000248450.4
 AAMP
 angio-associated, migratory cell protein
chr22_-_38245304 0.13 ENST00000609454.1
 ANKRD54
 ankyrin repeat domain 54
chr2_+_109271481 0.13 ENST00000542845.1
ENST00000393314.2
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr10_+_112836779 0.13 ENST00000280155.2
 ADRA2A
 adrenoceptor alpha 2A
chrX_+_16141667 0.13 ENST00000380289.2
 GRPR
 gastrin-releasing peptide receptor
chr1_-_8000872 0.13 ENST00000377507.3
 TNFRSF9
 tumor necrosis factor receptor superfamily, member 9
chr19_+_50706866 0.12 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
 MYH14
 myosin, heavy chain 14, non-muscle
chr1_+_36690011 0.12 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
 THRAP3
 thyroid hormone receptor associated protein 3
chr8_-_101348408 0.12 ENST00000519527.1
ENST00000522369.1
 RNF19A
 ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr11_-_64512803 0.12 ENST00000377489.1
ENST00000354024.3
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr5_+_137514687 0.11 ENST00000394894.3
 KIF20A
 kinesin family member 20A
chr14_-_24701539 0.11 ENST00000534348.1
ENST00000524927.1
ENST00000250495.5
 NEDD8-MDP1
NEDD8
 NEDD8-MDP1 readthrough
neural precursor cell expressed, developmentally down-regulated 8
chr3_+_171561127 0.11 ENST00000334567.5
ENST00000450693.1
 TMEM212
 transmembrane protein 212
chr11_+_118478313 0.11 ENST00000356063.5
 PHLDB1
 pleckstrin homology-like domain, family B, member 1
chr10_+_115439630 0.11 ENST00000369318.3
 CASP7
 caspase 7, apoptosis-related cysteine peptidase
chr19_+_42746927 0.11 ENST00000378108.1
 AC006486.1
 AC006486.1
chrX_-_40594755 0.11 ENST00000324817.1
 MED14
 mediator complex subunit 14
chr6_+_20403997 0.10 ENST00000535432.1
 E2F3
 E2F transcription factor 3
chr5_+_137514834 0.10 ENST00000508792.1
ENST00000504621.1
 KIF20A
 kinesin family member 20A
chr16_+_28962128 0.10 ENST00000564978.1
ENST00000320805.4
 NFATC2IP
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr10_-_38146510 0.10 ENST00000395867.3
 ZNF248
 zinc finger protein 248
chr2_+_187350973 0.10 ENST00000544130.1
 ZC3H15
 zinc finger CCCH-type containing 15
chrX_-_153236819 0.09 ENST00000354233.3
 HCFC1
 host cell factor C1 (VP16-accessory protein)
chr1_+_174769006 0.09 ENST00000489615.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr19_-_46088068 0.09 ENST00000263275.4
ENST00000323060.3
 OPA3
 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr9_-_35691017 0.09 ENST00000378292.3
 TPM2
 tropomyosin 2 (beta)
chr3_-_87325728 0.09 ENST00000350375.2
 POU1F1
 POU class 1 homeobox 1
chr1_+_150980989 0.09 ENST00000368935.1
 PRUNE
 prune exopolyphosphatase
chr6_+_33176265 0.09 ENST00000374656.4
 RING1
 ring finger protein 1
chr3_+_107241783 0.09 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
 BBX
 bobby sox homolog (Drosophila)
chr5_-_137514288 0.09 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
 BRD8
 bromodomain containing 8
chr2_+_204193101 0.08 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
 ABI2
 abl-interactor 2
chr17_-_39637392 0.08 ENST00000246639.2
ENST00000393989.1
 KRT35
 keratin 35
chr16_-_57831914 0.08 ENST00000421376.2
 KIFC3
 kinesin family member C3
chr11_-_64512469 0.08 ENST00000377485.1
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr8_+_107738240 0.07 ENST00000449762.2
ENST00000297447.6
 OXR1
 oxidation resistance 1
chr3_+_155860751 0.07 ENST00000471742.1
 KCNAB1
 potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr10_+_115439699 0.07 ENST00000369315.1
 CASP7
 caspase 7, apoptosis-related cysteine peptidase
chr2_+_106361333 0.07 ENST00000233154.4
ENST00000451463.2
 NCK2
 NCK adaptor protein 2
chr1_+_150980889 0.07 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
 PRUNE
 prune exopolyphosphatase
chr6_-_31510181 0.07 ENST00000458640.1
ENST00000396172.1
ENST00000417556.2
 DDX39B
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr19_+_39390320 0.07 ENST00000576510.1
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr19_-_36870087 0.06 ENST00000270001.7
 ZFP14
 ZFP14 zinc finger protein
chr11_-_64512273 0.06 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_30075595 0.06 ENST00000563060.2
 ALDOA
 aldolase A, fructose-bisphosphate
chr4_-_73935409 0.06 ENST00000507544.2
ENST00000295890.4
 COX18
 COX18 cytochrome C oxidase assembly factor
chr5_+_178322893 0.06 ENST00000361362.2
ENST00000520660.1
ENST00000520805.1
 ZFP2
 ZFP2 zinc finger protein
chr10_-_33623310 0.06 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
 NRP1
 neuropilin 1
chr16_+_30075463 0.06 ENST00000562168.1
ENST00000569545.1
 ALDOA
 aldolase A, fructose-bisphosphate
chr19_+_39390587 0.06 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr17_-_34257731 0.05 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
 RDM1
 RAD52 motif 1
chr1_+_8021954 0.05 ENST00000377491.1
ENST00000377488.1
 PARK7
 parkinson protein 7
chr4_+_26321284 0.05 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr2_+_183580954 0.05 ENST00000264065.7
 DNAJC10
 DnaJ (Hsp40) homolog, subfamily C, member 10
chr5_-_137514333 0.05 ENST00000411594.2
ENST00000430331.1
 BRD8
 bromodomain containing 8
chr1_-_43855444 0.05 ENST00000372455.4
 MED8
 mediator complex subunit 8
chrX_-_153236620 0.05 ENST00000369984.4
 HCFC1
 host cell factor C1 (VP16-accessory protein)
chrX_+_123095546 0.04 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
 STAG2
 stromal antigen 2
chr1_+_93297582 0.04 ENST00000370321.3
 RPL5
 ribosomal protein L5
chr6_-_76203345 0.04 ENST00000393004.2
 FILIP1
 filamin A interacting protein 1
chr13_-_39612176 0.04 ENST00000352251.3
ENST00000350125.3
 PROSER1
 proline and serine rich 1
chr3_+_32726774 0.03 ENST00000538368.1
 CNOT10
 CCR4-NOT transcription complex, subunit 10
chr14_-_53258180 0.03 ENST00000554230.1
 GNPNAT1
 glucosamine-phosphate N-acetyltransferase 1
chr2_-_79315112 0.03 ENST00000305089.3
 REG1B
 regenerating islet-derived 1 beta
chr14_-_53258314 0.03 ENST00000216410.3
ENST00000557604.1
 GNPNAT1
 glucosamine-phosphate N-acetyltransferase 1
chr5_+_178368186 0.03 ENST00000320129.3
ENST00000519564.1
 ZNF454
 zinc finger protein 454
chr19_+_50528971 0.03 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
 ZNF473
 zinc finger protein 473
chr16_+_21964662 0.03 ENST00000561553.1
ENST00000565331.1
 UQCRC2
 ubiquinol-cytochrome c reductase core protein II
chr15_-_70390191 0.03 ENST00000559191.1
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr3_-_87325612 0.03 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
 POU1F1
 POU class 1 homeobox 1
chr8_-_67974552 0.02 ENST00000357849.4
 COPS5
 COP9 signalosome subunit 5
chr11_-_8959758 0.02 ENST00000531618.1
 ASCL3
 achaete-scute family bHLH transcription factor 3
chr2_+_187350883 0.01 ENST00000337859.6
 ZC3H15
 zinc finger CCCH-type containing 15
chr19_-_17356697 0.01 ENST00000291442.3
 NR2F6
 nuclear receptor subfamily 2, group F, member 6
chr10_+_118305435 0.01 ENST00000369221.2
 PNLIP
 pancreatic lipase
chr5_+_132009675 0.01 ENST00000231449.2
ENST00000350025.2
 IL4
 interleukin 4
chr3_+_193853927 0.01 ENST00000232424.3
 HES1
 hes family bHLH transcription factor 1
chr1_+_93297622 0.01 ENST00000315741.5
 RPL5
 ribosomal protein L5
chr11_-_101454658 0.01 ENST00000344327.3
 TRPC6
 transient receptor potential cation channel, subfamily C, member 6
chr17_-_16118835 0.01 ENST00000582357.1
ENST00000436828.1
ENST00000411510.1
ENST00000268712.3
 NCOR1
 nuclear receptor corepressor 1
chr6_+_42531798 0.01 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr2_+_219824357 0.01 ENST00000302625.4
 CDK5R2
 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr1_+_43855560 0.01 ENST00000562955.1
 SZT2
 seizure threshold 2 homolog (mouse)
chr21_-_31538971 0.01 ENST00000286808.3
 CLDN17
 claudin 17
chr12_+_175930 0.01 ENST00000538872.1
ENST00000326261.4
 IQSEC3
 IQ motif and Sec7 domain 3
chr7_+_76090993 0.01 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
 DTX2
 deltex homolog 2 (Drosophila)
chr15_-_70390213 0.01 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr12_-_4758159 0.00 ENST00000545990.2
 AKAP3
 A kinase (PRKA) anchor protein 3
chr5_-_88119580 0.00 ENST00000539796.1
 MEF2C
 myocyte enhancer factor 2C
chr14_+_22337014 0.00 ENST00000390436.2
 TRAV13-1
 T cell receptor alpha variable 13-1

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005879 axonemal microtubule(GO:0005879)
0.2 0.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 1.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 1.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 0.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 1.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0048539 bone marrow development(GO:0048539)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 1.4 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.5 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.9 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:1902958 peptidyl-cysteine oxidation(GO:0018171) enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 1.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.5 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) cupric ion binding(GO:1903135)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.0 GO:0001618 virus receptor activity(GO:0001618)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions