ISMARA results: REL

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ENCODE cell lines, expression (Ernst 2011)

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Results for REL

Z-value: 1.18

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Transcription factors associated with REL

Gene Symbol	Gene ID	Gene Info
REL Ensembl NCBI GeneCards UniProt	ENSG00000162924.9	REL

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
REL	hg19_v2_chr2_+_61108650_61108687	0.18	5.1e-01	Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr11_-_58345569	4.07	ENST00000528954.1 ENST00000528489.1	LPXN	leupaxin
chr10_+_90750378	3.41	ENST00000355740.2 ENST00000352159.4	FAS	Fas cell surface death receptor
chr10_+_90750493	3.26	ENST00000357339.2 ENST00000355279.2	FAS	Fas cell surface death receptor
chr6_+_138188551	3.19	ENST00000237289.4 ENST00000433680.1	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr6_+_29910301	2.43	ENST00000376809.5 ENST00000376802.2	HLA-A	major histocompatibility complex, class I, A
chr19_-_6591113	2.08	ENST00000423145.3 ENST00000245903.3	CD70	CD70 molecule
chr7_+_69064300	1.85	ENST00000342771.4	AUTS2	autism susceptibility candidate 2
chr11_+_102188272	1.81	ENST00000532808.1	BIRC3	baculoviral IAP repeat containing 3
chr11_+_102188224	1.72	ENST00000263464.3	BIRC3	baculoviral IAP repeat containing 3
chr14_+_75988851	1.67	ENST00000555504.1	BATF	basic leucine zipper transcription factor, ATF-like
chr1_-_93426998	1.64	ENST00000370310.4	FAM69A	family with sequence similarity 69, member A
chr9_-_132805430	1.61	ENST00000446176.2 ENST00000355681.3 ENST00000420781.1	FNBP1	formin binding protein 1
chr9_-_117880477	1.61	ENST00000534839.1 ENST00000340094.3 ENST00000535648.1 ENST00000346706.3 ENST00000345230.3 ENST00000350763.4	TNC	tenascin C
chr5_-_149792295	1.56	ENST00000518797.1 ENST00000524315.1 ENST00000009530.7 ENST00000377795.3	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr20_+_44746885	1.51	ENST00000372285.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr18_+_21529811	1.50	ENST00000588004.1	LAMA3	laminin, alpha 3
chr5_+_49963239	1.48	ENST00000505554.1	PARP8	poly (ADP-ribose) polymerase family, member 8
chr8_-_119964434	1.45	ENST00000297350.4	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
chr5_-_150460914	1.39	ENST00000389378.2	TNIP1	TNFAIP3 interacting protein 1
chr8_-_49834299	1.38	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr18_+_21452804	1.35	ENST00000269217.6	LAMA3	laminin, alpha 3
chr18_+_21452964	1.32	ENST00000587184.1	LAMA3	laminin, alpha 3
chr6_+_32821924	1.31	ENST00000374859.2 ENST00000453265.2	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9
chr4_+_169418195	1.30	ENST00000261509.6 ENST00000335742.7	PALLD	palladin, cytoskeletal associated protein
chr19_+_4229495	1.29	ENST00000221847.5	EBI3	Epstein-Barr virus induced 3
chr12_-_77272765	1.27	ENST00000547435.1 ENST00000552330.1 ENST00000546966.1 ENST00000311083.5	CSRP2	cysteine and glycine-rich protein 2
chr2_-_88355241	1.23	ENST00000347055.3	KRCC1	lysine-rich coiled-coil 1
chr12_-_49318715	1.23	ENST00000444214.2	FKBP11	FK506 binding protein 11, 19 kDa
chr15_-_20193370	1.19	ENST00000558565.2	IGHV3OR15-7	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_-_191885686	1.19	ENST00000432058.1	STAT1	signal transducer and activator of transcription 1, 91kDa
chr20_+_44746939	1.18	ENST00000372276.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr15_+_33010175	1.15	ENST00000300177.4 ENST00000560677.1 ENST00000560830.1	GREM1	gremlin 1, DAN family BMP antagonist
chr10_-_97050777	1.14	ENST00000329399.6	PDLIM1	PDZ and LIM domain 1
chr8_-_49833978	1.14	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr9_-_136344197	1.10	ENST00000414172.1 ENST00000371897.4	SLC2A6	solute carrier family 2 (facilitated glucose transporter), member 6
chr5_-_150466692	1.08	ENST00000315050.7 ENST00000523338.1 ENST00000522100.1	TNIP1	TNFAIP3 interacting protein 1
chr10_+_13141585	1.06	ENST00000378764.2	OPTN	optineurin
chr17_-_7590745	1.05	ENST00000514944.1 ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4	TP53	tumor protein p53
chr15_+_85923797	1.04	ENST00000559362.1	AKAP13	A kinase (PRKA) anchor protein 13
chr12_+_7055631	1.03	ENST00000543115.1 ENST00000399448.1	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr12_+_53491220	1.02	ENST00000548547.1 ENST00000301464.3	IGFBP6	insulin-like growth factor binding protein 6
chr4_+_169418255	1.02	ENST00000505667.1 ENST00000511948.1	PALLD	palladin, cytoskeletal associated protein
chr7_-_47579188	1.01	ENST00000398879.1 ENST00000355730.3 ENST00000442536.2 ENST00000458317.2	TNS3	tensin 3
chr18_+_33877654	1.00	ENST00000257209.4 ENST00000445677.1 ENST00000590592.1 ENST00000359247.4	FHOD3	formin homology 2 domain containing 3
chr8_+_123793633	0.99	ENST00000314393.4	ZHX2	zinc fingers and homeoboxes 2
chr3_-_178789993	0.97	ENST00000432729.1	ZMAT3	zinc finger, matrin-type 3
chr3_+_57261743	0.96	ENST00000288266.3	APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr10_+_13142225	0.94	ENST00000378747.3	OPTN	optineurin
chr19_+_41725088	0.94	ENST00000301178.4	AXL	AXL receptor tyrosine kinase
chr5_+_82767284	0.93	ENST00000265077.3	VCAN	versican
chr10_+_13142075	0.91	ENST00000378757.2 ENST00000430081.1 ENST00000378752.3 ENST00000378748.3	OPTN	optineurin
chr14_+_75988768	0.91	ENST00000286639.6	BATF	basic leucine zipper transcription factor, ATF-like
chr19_-_50143452	0.88	ENST00000246792.3	RRAS	related RAS viral (r-ras) oncogene homolog
chr1_-_209824643	0.88	ENST00000391911.1 ENST00000415782.1	LAMB3	laminin, beta 3
chr11_+_119039414	0.88	ENST00000409991.1 ENST00000292199.2 ENST00000409265.4 ENST00000409109.1	NLRX1	NLR family member X1
chr17_+_34640031	0.83	ENST00000339270.6 ENST00000482104.1	CCL4L2	chemokine (C-C motif) ligand 4-like 2
chr10_-_96122682	0.81	ENST00000371361.3	NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)
chr3_-_178790057	0.79	ENST00000311417.2	ZMAT3	zinc finger, matrin-type 3
chr2_-_113594279	0.78	ENST00000416750.1 ENST00000418817.1 ENST00000263341.2	IL1B	interleukin 1, beta
chr20_-_43977055	0.78	ENST00000372733.3 ENST00000537976.1	SDC4	syndecan 4
chr2_-_163175133	0.78	ENST00000421365.2 ENST00000263642.2	IFIH1	interferon induced with helicase C domain 1
chr17_+_34639793	0.76	ENST00000394465.2 ENST00000394463.2 ENST00000378342.4	CCL4L2	chemokine (C-C motif) ligand 4-like 2
chr12_-_76425368	0.72	ENST00000602540.1	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr12_+_102271129	0.72	ENST00000258534.8	DRAM1	DNA-damage regulated autophagy modulator 1
chr10_+_89419370	0.71	ENST00000361175.4 ENST00000456849.1	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_+_7597639	0.70	ENST00000533792.1	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_-_54955721	0.67	ENST00000554908.1	GMFB	glia maturation factor, beta
chr6_-_32821599	0.66	ENST00000354258.4	TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_+_238600933	0.65	ENST00000420665.1 ENST00000392000.4	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr10_+_104155450	0.63	ENST00000471698.1 ENST00000189444.6	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_+_2476116	0.63	ENST00000215631.4 ENST00000587345.1	GADD45B	growth arrest and DNA-damage-inducible, beta
chr15_+_85923856	0.61	ENST00000560302.1 ENST00000394518.2 ENST00000361243.2 ENST00000560256.1	AKAP13	A kinase (PRKA) anchor protein 13
chr10_+_30722866	0.60	ENST00000263056.1	MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr6_-_31550192	0.60	ENST00000429299.2 ENST00000446745.2	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr2_+_90077680	0.59	ENST00000390270.2	IGKV3D-20	immunoglobulin kappa variable 3D-20
chr22_-_39268308	0.59	ENST00000407418.3	CBX6	chromobox homolog 6
chr2_+_228189941	0.59	ENST00000353339.3 ENST00000354503.6 ENST00000530359.1 ENST00000531278.1 ENST00000409565.1 ENST00000452930.1 ENST00000409616.1 ENST00000337110.7 ENST00000525195.1 ENST00000534203.1 ENST00000524634.1 ENST00000349901.7	MFF	mitochondrial fission factor
chr22_-_39268192	0.58	ENST00000216083.6	CBX6	chromobox homolog 6
chr6_+_292051	0.58	ENST00000344450.5	DUSP22	dual specificity phosphatase 22
chr1_-_204380919	0.57	ENST00000367188.4	PPP1R15B	protein phosphatase 1, regulatory subunit 15B
chr2_+_131975882	0.56	ENST00000356920.5 ENST00000358087.5	POTEE	POTE ankyrin domain family, member E
chr2_+_204193149	0.55	ENST00000422511.2	ABI2	abl-interactor 2
chr8_-_101321584	0.54	ENST00000523167.1	RNF19A	ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr6_-_29527702	0.54	ENST00000377050.4	UBD	ubiquitin D
chr2_+_204193101	0.53	ENST00000430418.1 ENST00000424558.1 ENST00000261016.6	ABI2	abl-interactor 2
chr16_+_50730910	0.53	ENST00000300589.2	NOD2	nucleotide-binding oligomerization domain containing 2
chr22_+_46067678	0.53	ENST00000381061.4 ENST00000252934.5	ATXN10	ataxin 10
chr15_+_71145578	0.53	ENST00000544974.2 ENST00000558546.1	LRRC49	leucine rich repeat containing 49
chr2_+_204193129	0.50	ENST00000417864.1	ABI2	abl-interactor 2
chr1_-_65432171	0.50	ENST00000342505.4	JAK1	Janus kinase 1
chr14_-_53417732	0.48	ENST00000399304.3 ENST00000395631.2 ENST00000341590.3 ENST00000343279.4	FERMT2	fermitin family member 2
chr20_-_44485835	0.48	ENST00000457981.1 ENST00000426915.1 ENST00000217455.4	ACOT8	acyl-CoA thioesterase 8
chr8_+_70404996	0.46	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr15_+_67430339	0.45	ENST00000439724.3	SMAD3	SMAD family member 3
chr16_+_27325202	0.44	ENST00000395762.2 ENST00000562142.1 ENST00000561742.1 ENST00000543915.2 ENST00000449195.1 ENST00000380922.3 ENST00000563002.1	IL4R	interleukin 4 receptor
chr20_+_43803517	0.43	ENST00000243924.3	PI3	peptidase inhibitor 3, skin-derived
chr19_-_41256207	0.41	ENST00000598485.2 ENST00000470681.1 ENST00000339153.3 ENST00000598729.1	C19orf54	chromosome 19 open reading frame 54
chr14_-_106610852	0.40	ENST00000390603.2	IGHV3-15	immunoglobulin heavy variable 3-15
chr4_+_26322185	0.40	ENST00000361572.6	RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr5_-_55290773	0.40	ENST00000502326.3 ENST00000381298.2	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr21_+_34775181	0.40	ENST00000290219.6	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr8_-_23712312	0.40	ENST00000290271.2	STC1	stanniocalcin 1
chr16_+_31044812	0.40	ENST00000313843.3	STX4	syntaxin 4
chr2_+_220094479	0.39	ENST00000323348.5 ENST00000453432.1 ENST00000409849.1 ENST00000416565.1 ENST00000410034.3 ENST00000447157.1	ANKZF1	ankyrin repeat and zinc finger domain containing 1
chr14_-_35873856	0.38	ENST00000553342.1 ENST00000216797.5 ENST00000557140.1	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr19_-_51472031	0.36	ENST00000391808.1	KLK6	kallikrein-related peptidase 6
chr21_+_34775698	0.36	ENST00000381995.1	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr22_+_22712087	0.36	ENST00000390294.2	IGLV1-47	immunoglobulin lambda variable 1-47
chr12_+_56211703	0.36	ENST00000243045.5 ENST00000552672.1 ENST00000550836.1	ORMDL2	ORM1-like 2 (S. cerevisiae)
chr12_-_9913489	0.35	ENST00000228434.3 ENST00000536709.1	CD69	CD69 molecule
chr5_+_14143728	0.34	ENST00000344204.4 ENST00000537187.1	TRIO	trio Rho guanine nucleotide exchange factor
chr21_+_34775772	0.34	ENST00000405436.1	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_41725140	0.33	ENST00000359092.3	AXL	AXL receptor tyrosine kinase
chr16_-_15736953	0.33	ENST00000548025.1 ENST00000551742.1 ENST00000602337.1 ENST00000344181.3 ENST00000396368.3	KIAA0430	KIAA0430
chr16_-_15736881	0.32	ENST00000540441.2	KIAA0430	KIAA0430
chr17_-_8286484	0.32	ENST00000582556.1 ENST00000584164.1 ENST00000293842.5 ENST00000584343.1 ENST00000578812.1 ENST00000583011.1	RPL26	ribosomal protein L26
chr2_+_163175394	0.30	ENST00000446271.1 ENST00000429691.2	GCA	grancalcin, EF-hand calcium binding protein
chr15_+_22892663	0.30	ENST00000313077.7 ENST00000561274.1 ENST00000560848.1	CYFIP1	cytoplasmic FMR1 interacting protein 1
chr22_+_46546494	0.30	ENST00000396000.2 ENST00000262735.5 ENST00000420804.1	PPARA	peroxisome proliferator-activated receptor alpha
chr2_+_162016916	0.29	ENST00000405852.1	TANK	TRAF family member-associated NFKB activator
chr7_+_156742399	0.29	ENST00000275820.3	NOM1	nucleolar protein with MIF4G domain 1
chr1_+_16767195	0.28	ENST00000504551.2 ENST00000457722.2 ENST00000406746.1 ENST00000443980.2	NECAP2	NECAP endocytosis associated 2
chr11_+_10476851	0.28	ENST00000396553.2	AMPD3	adenosine monophosphate deaminase 3
chr20_-_36156293	0.28	ENST00000373537.2 ENST00000414542.2	BLCAP	bladder cancer associated protein
chr5_+_133984462	0.28	ENST00000398844.2 ENST00000322887.4	SEC24A	SEC24 family member A
chr16_-_122619	0.27	ENST00000262316.6	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr19_+_41256764	0.27	ENST00000243563.3 ENST00000601253.1 ENST00000597353.1 ENST00000599362.1	SNRPA	small nuclear ribonucleoprotein polypeptide A
chr2_+_204192942	0.27	ENST00000295851.5 ENST00000261017.5	ABI2	abl-interactor 2
chr3_+_183967409	0.26	ENST00000324557.4 ENST00000402825.3	ECE2	endothelin converting enzyme 2
chr21_+_34638656	0.26	ENST00000290200.2	IL10RB	interleukin 10 receptor, beta
chr13_-_38443860	0.26	ENST00000426868.2 ENST00000379681.3 ENST00000338947.5 ENST00000355779.2 ENST00000358477.2 ENST00000379673.2	TRPC4	transient receptor potential cation channel, subfamily C, member 4
chr10_+_17270214	0.25	ENST00000544301.1	VIM	vimentin
chr19_-_51471362	0.25	ENST00000376853.4 ENST00000424910.2	KLK6	kallikrein-related peptidase 6
chr3_+_197518100	0.24	ENST00000438796.2 ENST00000414675.2 ENST00000441090.2 ENST00000334859.4 ENST00000425562.2	LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3
chr1_-_113249948	0.24	ENST00000339083.7 ENST00000369642.3	RHOC	ras homolog family member C
chr19_-_4831701	0.23	ENST00000248244.5	TICAM1	toll-like receptor adaptor molecule 1
chr11_+_46299199	0.23	ENST00000529193.1 ENST00000288400.3	CREB3L1	cAMP responsive element binding protein 3-like 1
chrX_-_17878827	0.23	ENST00000360011.1	RAI2	retinoic acid induced 2
chr2_+_90153696	0.23	ENST00000417279.2	IGKV3D-15	immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr5_+_150591678	0.22	ENST00000523466.1	GM2A	GM2 ganglioside activator
chr3_+_42201653	0.22	ENST00000341421.3 ENST00000396175.1	TRAK1	trafficking protein, kinesin binding 1
chr17_-_4852332	0.21	ENST00000572383.1	PFN1	profilin 1
chr4_-_185395672	0.21	ENST00000393593.3	IRF2	interferon regulatory factor 2
chr16_+_15737124	0.21	ENST00000396355.1 ENST00000396353.2	NDE1	nudE neurodevelopment protein 1
chr3_-_139108475	0.20	ENST00000515006.1 ENST00000513274.1 ENST00000514508.1 ENST00000507777.1 ENST00000512153.1 ENST00000333188.5	COPB2	coatomer protein complex, subunit beta 2 (beta prime)
chr2_+_208394794	0.20	ENST00000536726.1 ENST00000374397.4 ENST00000452474.1	CREB1	cAMP responsive element binding protein 1
chr9_-_34637806	0.20	ENST00000477726.1	SIGMAR1	sigma non-opioid intracellular receptor 1
chr12_-_40013553	0.20	ENST00000308666.3	ABCD2	ATP-binding cassette, sub-family D (ALD), member 2
chr6_-_44233361	0.20	ENST00000275015.5	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr16_+_53088885	0.20	ENST00000566029.1 ENST00000447540.1	CHD9	chromodomain helicase DNA binding protein 9
chr19_-_39390440	0.20	ENST00000249396.7 ENST00000414941.1 ENST00000392081.2	SIRT2	sirtuin 2
chr6_-_131384373	0.20	ENST00000392427.3 ENST00000525271.1 ENST00000527411.1	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr17_-_1420182	0.20	ENST00000421807.2	INPP5K	inositol polyphosphate-5-phosphatase K
chr19_+_14142535	0.19	ENST00000263379.2	IL27RA	interleukin 27 receptor, alpha
chr4_-_176733897	0.19	ENST00000393658.2	GPM6A	glycoprotein M6A
chr11_-_66313699	0.19	ENST00000526986.1 ENST00000310442.3	ZDHHC24	zinc finger, DHHC-type containing 24
chr10_+_104154229	0.19	ENST00000428099.1 ENST00000369966.3	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_-_51471381	0.18	ENST00000594641.1	KLK6	kallikrein-related peptidase 6
chr3_+_179322573	0.18	ENST00000493866.1 ENST00000472629.1 ENST00000482604.1	NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr2_-_89310012	0.18	ENST00000493819.1	IGKV1-9	immunoglobulin kappa variable 1-9
chr2_+_114647504	0.18	ENST00000263238.2	ACTR3	ARP3 actin-related protein 3 homolog (yeast)
chr11_+_19798964	0.17	ENST00000527559.2	NAV2	neuron navigator 2
chr6_-_131384347	0.17	ENST00000530481.1	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr2_-_18741882	0.17	ENST00000381249.3	RDH14	retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr14_-_30396802	0.16	ENST00000415220.2	PRKD1	protein kinase D1
chr1_-_62190793	0.16	ENST00000371177.2 ENST00000606498.1	TM2D1	TM2 domain containing 1
chr4_+_114214125	0.16	ENST00000509550.1	ANK2	ankyrin 2, neuronal
chr17_-_16118835	0.15	ENST00000582357.1 ENST00000436828.1 ENST00000411510.1 ENST00000268712.3	NCOR1	nuclear receptor corepressor 1
chr7_-_16844611	0.15	ENST00000401412.1 ENST00000419304.2	AGR2	anterior gradient 2
chr11_+_66406149	0.14	ENST00000578778.1 ENST00000483858.1 ENST00000398692.4 ENST00000510173.2 ENST00000506523.2 ENST00000530235.1 ENST00000532968.1	RBM4	RNA binding motif protein 4
chr12_-_56727676	0.14	ENST00000547572.1 ENST00000257931.5 ENST00000440411.3	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr9_-_115480303	0.13	ENST00000374234.1 ENST00000374238.1 ENST00000374236.1 ENST00000374242.4	INIP	INTS3 and NABP interacting protein
chr19_+_18794470	0.13	ENST00000321949.8 ENST00000338797.6	CRTC1	CREB regulated transcription coactivator 1
chr3_+_179322481	0.12	ENST00000259037.3	NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr15_-_89755034	0.12	ENST00000563254.1	RLBP1	retinaldehyde binding protein 1
chr6_+_152126790	0.12	ENST00000456483.2	ESR1	estrogen receptor 1
chr18_+_3252265	0.11	ENST00000580887.1 ENST00000536605.1	MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric
chr1_-_159894319	0.11	ENST00000320307.4	TAGLN2	transgelin 2
chr20_-_36156125	0.11	ENST00000397135.1 ENST00000397137.1	BLCAP	bladder cancer associated protein
chr1_-_6453426	0.11	ENST00000545482.1	ACOT7	acyl-CoA thioesterase 7
chr8_+_39442097	0.10	ENST00000265707.5 ENST00000379866.1 ENST00000520772.1 ENST00000541111.1	ADAM18	ADAM metallopeptidase domain 18
chr19_-_39390350	0.10	ENST00000447739.1 ENST00000358931.5 ENST00000407552.1	SIRT2	sirtuin 2
chr16_+_84209539	0.10	ENST00000569735.1	DNAAF1	dynein, axonemal, assembly factor 1
chr9_+_101705893	0.10	ENST00000375001.3	COL15A1	collagen, type XV, alpha 1
chr14_-_30396948	0.10	ENST00000331968.5	PRKD1	protein kinase D1
chr11_+_19799327	0.09	ENST00000540292.1	NAV2	neuron navigator 2
chr17_+_26662730	0.09	ENST00000226225.2	TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr16_-_75498553	0.08	ENST00000569276.1 ENST00000357613.4 ENST00000561878.1 ENST00000566980.1 ENST00000567194.1	TMEM170A RP11-77K12.1	transmembrane protein 170A Uncharacterized protein
chr22_-_46659219	0.08	ENST00000253255.5	PKDREJ	polycystin (PKD) family receptor for egg jelly
chr6_-_131291572	0.08	ENST00000529208.1	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr6_-_46048116	0.08	ENST00000185206.6	CLIC5	chloride intracellular channel 5
chr10_+_49514698	0.07	ENST00000432379.1 ENST00000429041.1 ENST00000374189.1	MAPK8	mitogen-activated protein kinase 8
chr17_-_1420006	0.06	ENST00000320345.6 ENST00000406424.4	INPP5K	inositol polyphosphate-5-phosphatase K
chr7_-_98741714	0.06	ENST00000361125.1	SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr2_+_162016827	0.06	ENST00000429217.1 ENST00000406287.1 ENST00000402568.1	TANK	TRAF family member-associated NFKB activator
chr16_+_67282853	0.06	ENST00000299798.11	SLC9A5	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr3_+_89156674	0.06	ENST00000336596.2	EPHA3	EPH receptor A3
chr11_-_61734599	0.06	ENST00000532601.1	FTH1	ferritin, heavy polypeptide 1
chr9_+_130547958	0.06	ENST00000421939.1 ENST00000373265.2	CDK9	cyclin-dependent kinase 9
chr22_-_43036607	0.06	ENST00000505920.1	ATP5L2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.4	21.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.4	8.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	3.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	6.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	2.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	5.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.9	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1	3.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	3.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	4.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	5.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	3.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	2.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	2.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	2.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	2.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	4.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	2.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	4.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	2.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	4.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.3	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.3	0.9	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	1.7	GO:0016012	sarcoglycan complex(GO:0016012)
0.2	4.0	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	1.4	GO:0005610	laminin-5 complex(GO:0005610)
0.2	3.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	1.3	GO:0005587	collagen type IV trimer(GO:0005587)
0.2	1.7	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.8	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	1.0	GO:0019815	B cell receptor complex(GO:0019815)
0.1	4.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.8	GO:0042825	TAP complex(GO:0042825)
0.1	0.3	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	0.7	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.3	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.6	GO:0032010	phagolysosome(GO:0032010)
0.1	0.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	4.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.3	GO:1902560	GMP reductase complex(GO:1902560)
0.0	0.6	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.2	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0	0.4	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:0016938	kinesin I complex(GO:0016938)
0.0	1.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.2	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	5.3	GO:0005884	actin filament(GO:0005884)
0.0	0.3	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	1.8	GO:0002102	podosome(GO:0002102)
0.0	1.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	1.6	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.5	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	6.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.7	GO:0032420	stereocilium(GO:0032420)
0.0	3.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0002081	outer acrosomal membrane(GO:0002081)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.3	GO:0097342	ripoptosome(GO:0097342)
0.0	1.8	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	1.1	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.4	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.9	GO:1904724	specific granule lumen(GO:0035580) tertiary granule lumen(GO:1904724)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.4	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)
0.0	0.5	GO:1904115	axon cytoplasm(GO:1904115)
0.0	1.6	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	3.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	3.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	4.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.5	PID RAS PATHWAY	Regulation of Ras family activation
0.0	4.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	1.3	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	1.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	1.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.6	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	3.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	2.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.0	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.7	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.2	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.5	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.7	2.8	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.6	1.9	GO:0044501	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.5	2.2	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5	1.4	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.4	3.5	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.4	1.3	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.4	1.7	GO:0021564	vagus nerve development(GO:0021564)
0.4	0.4	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.4	1.5	GO:2001153	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.4	4.2	GO:0009414	response to water deprivation(GO:0009414)
0.4	1.9	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.4	2.9	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.4	3.6	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.3	1.3	GO:0000103	sulfate assimilation(GO:0000103)
0.3	1.2	GO:0002572	pro-T cell differentiation(GO:0002572)
0.3	0.8	GO:0034146	B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2	0.7	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2	2.0	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.2	0.8	GO:0046967	cytosol to ER transport(GO:0046967)
0.2	0.5	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2	1.7	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.2	0.6	GO:2000697	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.2	1.4	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2	0.5	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2	1.7	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.2	0.5	GO:0036071	N-glycan fucosylation(GO:0036071)
0.1	1.1	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	3.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.4	GO:2000777	positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1	0.5	GO:0052501	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of type B pancreatic cell development(GO:2000078)
0.1	0.6	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1	0.7	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.1	0.6	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1	0.3	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.1	0.1	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1	0.3	GO:0031346	positive regulation of cell projection organization(GO:0031346)
0.1	0.2	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	1.7	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.7	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.9	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.3	GO:1904457	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1	0.8	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1	0.3	GO:2000317	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1	0.3	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.3	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	1.0	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.4	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.1	2.0	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1	0.4	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	4.0	GO:0097435	fibril organization(GO:0097435)
0.1	0.9	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1	0.1	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.1	0.7	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.1	0.2	GO:0007497	posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.1	0.2	GO:0002384	hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1	1.3	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	1.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	1.2	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.0	1.3	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.2	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.1	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.0	0.4	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.9	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.0	GO:0050713	regulation of interleukin-1 beta secretion(GO:0050706) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.2	GO:0090107	regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0	0.8	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.0	0.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.8	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.0	0.7	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.5	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.9	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.3	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.6	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.8	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.8	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.0	2.8	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.9	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.0	0.3	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.3	GO:0043584	nose development(GO:0043584)
0.0	0.2	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.3	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.5	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.3	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.0	0.7	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	1.6	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0	0.2	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0	0.9	GO:0006536	glutamate metabolic process(GO:0006536)
0.0	0.6	GO:0045730	respiratory burst(GO:0045730)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.3	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.3	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.4	GO:0042127	regulation of cell proliferation(GO:0042127)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:2000360	positive regulation of female gonad development(GO:2000196) regulation of ovarian follicle development(GO:2000354) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0	3.0	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.2	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	1.9	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.1	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.2	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.5	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.0	0.0	GO:0090045	positive regulation of deacetylase activity(GO:0090045)
0.0	0.3	GO:0006144	purine nucleobase metabolic process(GO:0006144)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.4	1.3	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4	2.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.4	1.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.3	1.6	GO:0047820	D-glutamate cyclase activity(GO:0047820)
0.3	6.0	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.3	1.5	GO:0042577	lipid phosphatase activity(GO:0042577)
0.2	3.5	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.2	1.6	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.2	2.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.2	0.9	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.2	1.6	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.2	2.5	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	0.6	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.5	GO:0046921	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1	2.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.8	GO:0046979	TAP2 binding(GO:0046979)
0.1	0.4	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1	1.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1	3.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	1.7	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.7	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	1.2	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.3	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.3	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.1	0.3	GO:0004348	glucosylceramidase activity(GO:0004348)
0.1	0.6	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.3	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	1.9	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.4	GO:1903135	cupric ion binding(GO:1903135)
0.1	1.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	0.2	GO:0004962	endothelin receptor activity(GO:0004962)
0.1	0.3	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	1.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	4.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.0	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.0	0.3	GO:0031433	telethonin binding(GO:0031433)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.2	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.5	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	1.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.4	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	1.4	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0016972	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.0	0.2	GO:0043559	insulin binding(GO:0043559)
0.0	3.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.7	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.7	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.9	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.9	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.5	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	3.5	GO:0005178	integrin binding(GO:0005178)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.0	0.4	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.2	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.3	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.6	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	1.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0031435	MAP kinase kinase kinase kinase activity(GO:0008349) mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.0	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	5.9	GO:0042289	MHC class II protein binding(GO:0042289)
1.0	4.1	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.9	9.4	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.9	11.5	GO:0032395	MHC class II receptor activity(GO:0032395)
0.8	4.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.7	4.0	GO:0046979	TAP2 binding(GO:0046979)
0.6	3.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.3	3.6	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3	13.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	3.2	GO:0008199	ferric iron binding(GO:0008199)
0.2	10.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2	1.7	GO:0019863	IgE binding(GO:0019863)
0.2	1.5	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.2	0.5	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2	1.4	GO:1990763	arrestin family protein binding(GO:1990763)
0.2	1.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.2	2.6	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.7	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.1	1.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1	0.4	GO:0097677	STAT family protein binding(GO:0097677)
0.1	1.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	5.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	2.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	1.8	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	1.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	3.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	2.9	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.4	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.1	3.9	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	1.8	GO:0070628	proteasome binding(GO:0070628)
0.1	0.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	2.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.7	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	2.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.9	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.5	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.3	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	2.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.9	GO:0043422	protein kinase B binding(GO:0043422)
0.1	1.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	1.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	1.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.5	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	2.5	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	6.5	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.3	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.6	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	13.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.8	5.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.7	2.0	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.6	11.5	GO:0042613	MHC class II protein complex(GO:0042613)
0.5	5.7	GO:0042612	MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.5	3.6	GO:0019815	B cell receptor complex(GO:0019815)
0.5	3.3	GO:0043196	varicosity(GO:0043196)
0.4	2.5	GO:0032584	growth cone membrane(GO:0032584)
0.2	0.7	GO:0071746	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.2	1.7	GO:0005610	laminin-5 complex(GO:0005610)
0.2	0.6	GO:0031251	PAN complex(GO:0031251)
0.2	1.4	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.2	2.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	0.5	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1	0.5	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1	1.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	4.7	GO:0097542	ciliary tip(GO:0097542)
0.1	0.5	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	4.9	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0	0.9	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	13.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	1.9	GO:0002102	podosome(GO:0002102)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.7	GO:0000145	exocyst(GO:0000145)
0.0	1.9	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	1.4	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	1.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	9.5	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	2.4	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	1.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	1.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.6	GO:0031594	neuromuscular junction(GO:0031594)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.7	GO:1990108	protein linear deubiquitination(GO:1990108)
1.6	4.7	GO:0034146	B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
1.4	1.4	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.3	3.9	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3	3.8	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
1.2	10.7	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
1.2	5.9	GO:0002905	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.8	3.1	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
0.8	3.8	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.8	2.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.8	6.0	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.7	2.8	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.7	4.9	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.7	3.3	GO:0033590	response to cobalamin(GO:0033590)
0.7	2.0	GO:0051300	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.6	3.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.6	2.4	GO:0072183	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.6	5.2	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.6	5.7	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.6	2.8	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.5	2.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.4	6.7	GO:0060263	regulation of respiratory burst(GO:0060263)
0.4	2.6	GO:0016554	cytidine to uridine editing(GO:0016554)
0.4	3.2	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.4	1.2	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.4	1.9	GO:0070842	aggresome assembly(GO:0070842)
0.4	1.1	GO:1904897	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4	7.0	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.4	1.5	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of macrophage apoptotic process(GO:2000110)
0.3	2.6	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.3	3.6	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3	2.4	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3	4.5	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.2	1.2	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.2	0.5	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2	1.4	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.2	0.8	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	0.6	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.2	1.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.2	0.5	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2	0.9	GO:0007296	vitellogenesis(GO:0007296)
0.2	1.4	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.1	1.6	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.1	0.4	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1	0.3	GO:0060584	positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.4	GO:0051685	maintenance of ER location(GO:0051685)
0.1	14.0	GO:0031295	T cell costimulation(GO:0031295)
0.1	0.7	GO:0006196	AMP catabolic process(GO:0006196)
0.1	2.7	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.4	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1	0.5	GO:0050821	protein stabilization(GO:0050821)
0.1	1.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	2.6	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.1	0.7	GO:0051601	exocyst localization(GO:0051601)
0.1	0.3	GO:0021590	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.1	0.5	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	1.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.5	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.3	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.9	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.2	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.3	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	2.7	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.0	3.7	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.4	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.2	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.4	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.0	0.8	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.2	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	2.9	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.7	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.5	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0002295	T-helper cell lineage commitment(GO:0002295)
0.0	0.9	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.3	GO:1904996	PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0	0.8	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.0	0.7	GO:0003094	glomerular filtration(GO:0003094)
0.0	0.6	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	1.5	GO:0090003	regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.7	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.3	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.4	GO:0016180	snRNA processing(GO:0016180)
0.0	0.2	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	1.0	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	3.1	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	1.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.9	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.5	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.6	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.3	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0097190	apoptotic signaling pathway(GO:0097190)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.0	GO:0005610	laminin-5 complex(GO:0005610)
0.4	2.7	GO:0043196	varicosity(GO:0043196)
0.3	6.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.2	1.6	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	2.4	GO:0042612	MHC class I protein complex(GO:0042612)
0.2	0.8	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.2	1.9	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.2	GO:0097342	ripoptosome(GO:0097342)
0.1	1.6	GO:0031209	SCAR complex(GO:0031209)
0.1	0.7	GO:0042825	TAP complex(GO:0042825)
0.1	1.0	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	5.7	GO:0002102	podosome(GO:0002102)
0.1	0.4	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	1.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	1.3	GO:0033643	host cell part(GO:0033643)
0.1	0.4	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.7	GO:0043219	lateral loop(GO:0043219)
0.1	0.5	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.2	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	2.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.4	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	1.0	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	1.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.4	GO:0008091	spectrin(GO:0008091)
0.0	1.0	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	1.1	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	1.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.9	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	0.5	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	1.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0044297	cell body(GO:0044297)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.5	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0098651	basement membrane collagen trimer(GO:0098651)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	26.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	2.8	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.2	1.6	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	3.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	3.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	4.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	6.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	6.8	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	2.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	3.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	2.6	PID EPO PATHWAY	EPO signaling pathway
0.1	3.4	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	3.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	1.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	3.2	PID BCR 5PATHWAY	BCR signaling pathway
0.1	1.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	2.7	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	1.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.4	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.3	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.3	GO:0090291	negative regulation of osteoclast proliferation(GO:0090291)
1.1	6.7	GO:0036337	Fas signaling pathway(GO:0036337)
0.8	2.5	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.8	2.5	GO:0052027	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.6	5.1	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5	1.6	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.5	1.6	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.5	0.5	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.5	1.9	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4	2.7	GO:0033590	response to cobalamin(GO:0033590)
0.4	2.9	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.4	1.4	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.4	1.1	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.3	3.5	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.3	1.6	GO:0002905	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3	1.2	GO:0046725	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.3	0.8	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2	2.4	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2	2.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	1.3	GO:2000669	positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.2	0.8	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.2	0.6	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2	0.8	GO:0034343	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2	0.5	GO:0045210	FasL biosynthetic process(GO:0045210)
0.2	0.7	GO:0000103	sulfate assimilation(GO:0000103)
0.2	5.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	0.7	GO:0046967	cytosol to ER transport(GO:0046967)
0.2	1.3	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2	0.8	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.1	0.4	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1	2.6	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.4	GO:0072554	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1	0.4	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1	0.4	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.4	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1	0.6	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.1	0.2	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.5	GO:0070842	aggresome assembly(GO:0070842)
0.1	2.3	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.4	GO:0048861	oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.3	GO:2000777	positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1	0.7	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	0.5	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	0.9	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	0.4	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1	0.3	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.3	GO:2001151	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1	0.6	GO:1903912	negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1	0.3	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.3	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1	0.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.5	GO:0016559	peroxisome fission(GO:0016559)
0.1	0.2	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1	0.5	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	1.0	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.3	GO:0006196	AMP catabolic process(GO:0006196)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	1.5	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.2	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	1.1	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.3	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.9	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.6	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.4	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.4	GO:0060536	cartilage morphogenesis(GO:0060536)
0.0	0.6	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.2	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	1.0	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:1900535	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0	3.0	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	1.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.3	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.1	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
0.0	0.5	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.2	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	1.6	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.2	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.4	GO:0007620	copulation(GO:0007620)
0.0	0.2	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.3	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.3	GO:0048820	hair follicle maturation(GO:0048820)
0.0	0.3	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.2	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.5	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.5	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.0	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.0	1.0	GO:0090003	regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0	0.3	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	0.1	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.2	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	2.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	6.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	3.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	7.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.8	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	1.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	2.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	5.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	1.7	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	4.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	2.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.1	0.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	3.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	2.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.9	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.4	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	1.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.3	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.8	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.8	PID BMP PATHWAY	BMP receptor signaling
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	6.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.3	3.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.3	1.6	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.7	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2	1.1	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.2	1.1	GO:0016015	morphogen activity(GO:0016015)
0.2	1.6	GO:0045545	syndecan binding(GO:0045545)
0.2	2.9	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	0.3	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	0.4	GO:0004913	interleukin-4 receptor activity(GO:0004913)
0.1	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	2.4	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	3.8	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.4	GO:0019981	interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) interleukin-6 binding(GO:0019981)
0.1	1.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1	0.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.7	GO:0046979	TAP2 binding(GO:0046979)
0.1	1.6	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	2.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	2.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1	1.0	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.5	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	1.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	0.7	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	1.9	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	3.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.2	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1	0.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.5	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	1.0	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.4	GO:0042731	PH domain binding(GO:0042731)
0.0	1.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	1.3	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.3	GO:1990254	keratin filament binding(GO:1990254)
0.0	1.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	1.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.0	1.0	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.3	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.4	GO:0000150	recombinase activity(GO:0000150)
0.0	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	2.9	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.5	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	1.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	3.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.5	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.2	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	2.0	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.9	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)

Results for REL

Z-value: 1.18

Motif logo

Transcription factors associated with REL

Activity-expression correlation:

Activity profile of REL motif

Sorted Z-values of REL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in molecular_function category: