ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
RELA Links Ensembl NCBI GeneCards UniProt	ENSG00000173039.14	RELA

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RELA	hg19_v2_chr11_-_65430251_65430399	0.19	4.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr5_-_149792295	5.93	ENST00000518797.1 ENST00000524315.1 ENST00000009530.7 ENST00000377795.3	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr11_+_102188272	5.47	ENST00000532808.1	BIRC3	baculoviral IAP repeat containing 3
chr11_+_102188224	5.24	ENST00000263464.3	BIRC3	baculoviral IAP repeat containing 3
chr12_-_9913489	5.10	ENST00000228434.3 ENST00000536709.1	CD69	CD69 molecule
chr14_+_75988851	5.09	ENST00000555504.1	BATF	basic leucine zipper transcription factor, ATF-like
chr19_-_6591113	4.89	ENST00000423145.3 ENST00000245903.3	CD70	CD70 molecule
chr6_+_138188551	4.68	ENST00000237289.4 ENST00000433680.1	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr22_-_37545972	4.40	ENST00000216223.5	IL2RB	interleukin 2 receptor, beta
chr6_+_32605134	4.37	ENST00000343139.5 ENST00000395363.1 ENST00000496318.1	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr6_+_32605195	4.34	ENST00000374949.2	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr11_-_58345569	3.97	ENST00000528954.1 ENST00000528489.1	LPXN	leupaxin
chr14_-_35873856	3.76	ENST00000553342.1 ENST00000216797.5 ENST00000557140.1	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr20_+_44746885	3.35	ENST00000372285.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr7_+_69064300	3.08	ENST00000342771.4	AUTS2	autism susceptibility candidate 2
chr4_-_76944621	2.85	ENST00000306602.1	CXCL10	chemokine (C-X-C motif) ligand 10
chr6_-_32636145	2.80	ENST00000399084.1	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr3_-_158390282	2.70	ENST00000264265.3	LXN	latexin
chr19_+_4229495	2.65	ENST00000221847.5	EBI3	Epstein-Barr virus induced 3
chr4_+_103422471	2.61	ENST00000226574.4 ENST00000394820.4	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr22_-_37640277	2.60	ENST00000401529.3 ENST00000249071.6	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_-_31550192	2.57	ENST00000429299.2 ENST00000446745.2	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr4_-_40631859	2.56	ENST00000295971.7 ENST00000319592.4	RBM47	RNA binding motif protein 47
chr10_+_30722866	2.44	ENST00000263056.1	MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr20_-_4795747	2.41	ENST00000379376.2	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr14_+_75988768	2.40	ENST00000286639.6	BATF	basic leucine zipper transcription factor, ATF-like
chr2_-_191885686	2.39	ENST00000432058.1	STAT1	signal transducer and activator of transcription 1, 91kDa
chr22_-_37640456	2.25	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_50776021	2.20	ENST00000566679.2 ENST00000564634.1 ENST00000398568.2	CYLD	cylindromatosis (turban tumor syndrome)
chr14_+_103243813	2.10	ENST00000560371.1 ENST00000347662.4 ENST00000392745.2 ENST00000539721.1 ENST00000560463.1	TRAF3	TNF receptor-associated factor 3
chr6_+_29691198	2.09	ENST00000440587.2 ENST00000434407.2	HLA-F	major histocompatibility complex, class I, F
chr6_+_31540056	2.07	ENST00000418386.2	LTA	lymphotoxin alpha
chr12_+_7055631	2.04	ENST00000543115.1 ENST00000399448.1	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr7_-_24797032	2.03	ENST00000409970.1 ENST00000409775.3	DFNA5	deafness, autosomal dominant 5
chrX_-_73072534	2.00	ENST00000429829.1	XIST	X inactive specific transcript (non-protein coding)
chr14_+_61789382	1.97	ENST00000555082.1	PRKCH	protein kinase C, eta
chr6_-_29527702	1.95	ENST00000377050.4	UBD	ubiquitin D
chr6_+_29691056	1.87	ENST00000414333.1 ENST00000334668.4 ENST00000259951.7	HLA-F	major histocompatibility complex, class I, F
chr10_+_12391481	1.87	ENST00000378847.3	CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr19_+_42381173	1.85	ENST00000221972.3	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr7_-_24797546	1.85	ENST00000414428.1 ENST00000419307.1 ENST00000342947.3	DFNA5	deafness, autosomal dominant 5
chr1_+_111770278	1.80	ENST00000369748.4	CHI3L2	chitinase 3-like 2
chr1_+_111770232	1.78	ENST00000369744.2	CHI3L2	chitinase 3-like 2
chr19_+_42381337	1.77	ENST00000597454.1 ENST00000444740.2	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr6_+_29910301	1.77	ENST00000376809.5 ENST00000376802.2	HLA-A	major histocompatibility complex, class I, A
chr19_+_2476116	1.74	ENST00000215631.4 ENST00000587345.1	GADD45B	growth arrest and DNA-damage-inducible, beta
chr19_-_7766991	1.73	ENST00000597921.1 ENST00000346664.5	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr19_-_11688447	1.72	ENST00000590420.1	ACP5	acid phosphatase 5, tartrate resistant
chr2_+_61108650	1.67	ENST00000295025.8	REL	v-rel avian reticuloendotheliosis viral oncogene homolog
chr2_-_163175133	1.64	ENST00000421365.2 ENST00000263642.2	IFIH1	interferon induced with helicase C domain 1
chr20_+_9494987	1.55	ENST00000427562.2 ENST00000246070.2	LAMP5	lysosomal-associated membrane protein family, member 5
chr10_+_104155450	1.54	ENST00000471698.1 ENST00000189444.6	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_-_76928641	1.53	ENST00000264888.5	CXCL9	chemokine (C-X-C motif) ligand 9
chr16_+_50775971	1.51	ENST00000311559.9 ENST00000564326.1 ENST00000566206.1	CYLD	cylindromatosis (turban tumor syndrome)
chr5_-_150460539	1.48	ENST00000520931.1 ENST00000520695.1 ENST00000521591.1 ENST00000518977.1	TNIP1	TNFAIP3 interacting protein 1
chr19_-_11688500	1.47	ENST00000433365.2	ACP5	acid phosphatase 5, tartrate resistant
chr17_-_34207295	1.45	ENST00000463941.1 ENST00000293272.3	CCL5	chemokine (C-C motif) ligand 5
chr16_+_50730910	1.40	ENST00000300589.2	NOD2	nucleotide-binding oligomerization domain containing 2
chr5_-_150460914	1.35	ENST00000389378.2	TNIP1	TNFAIP3 interacting protein 1
chr15_+_85923797	1.33	ENST00000559362.1	AKAP13	A kinase (PRKA) anchor protein 13
chr1_+_156123359	1.30	ENST00000368284.1 ENST00000368286.2 ENST00000438830.1	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_-_4793274	1.30	ENST00000414938.1	EGOT	eosinophil granule ontogeny transcript (non-protein coding)
chr22_-_39268308	1.28	ENST00000407418.3	CBX6	chromobox homolog 6
chr19_+_45504688	1.28	ENST00000221452.8 ENST00000540120.1 ENST00000505236.1	RELB	v-rel avian reticuloendotheliosis viral oncogene homolog B
chr3_+_53195136	1.28	ENST00000394729.2 ENST00000330452.3	PRKCD	protein kinase C, delta
chr1_+_156123318	1.28	ENST00000368285.3	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_209825674	1.26	ENST00000367030.3 ENST00000356082.4	LAMB3	laminin, beta 3
chr2_+_61108771	1.21	ENST00000394479.3	REL	v-rel avian reticuloendotheliosis viral oncogene homolog
chr17_-_7590745	1.21	ENST00000514944.1 ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4	TP53	tumor protein p53
chr6_+_106534192	1.20	ENST00000369091.2 ENST00000369096.4	PRDM1	PR domain containing 1, with ZNF domain
chr6_+_135502466	1.14	ENST00000367814.4	MYB	v-myb avian myeloblastosis viral oncogene homolog
chr22_-_39268192	1.07	ENST00000216083.6	CBX6	chromobox homolog 6
chr8_+_38758737	1.06	ENST00000521746.1 ENST00000420274.1	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr5_-_150466692	1.05	ENST00000315050.7 ENST00000523338.1 ENST00000522100.1	TNIP1	TNFAIP3 interacting protein 1
chr16_+_50775948	1.02	ENST00000569681.1 ENST00000569418.1 ENST00000540145.1	CYLD	cylindromatosis (turban tumor syndrome)
chr3_+_57261743	0.99	ENST00000288266.3	APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr15_+_85923856	0.94	ENST00000560302.1 ENST00000394518.2 ENST00000361243.2 ENST00000560256.1	AKAP13	A kinase (PRKA) anchor protein 13
chr12_+_11802753	0.93	ENST00000396373.4	ETV6	ets variant 6
chr10_+_104154229	0.91	ENST00000428099.1 ENST00000369966.3	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr9_-_136344197	0.91	ENST00000414172.1 ENST00000371897.4	SLC2A6	solute carrier family 2 (facilitated glucose transporter), member 6
chr6_+_292051	0.88	ENST00000344450.5	DUSP22	dual specificity phosphatase 22
chrX_-_30595959	0.86	ENST00000378962.3	CXorf21	chromosome X open reading frame 21
chr1_-_205744574	0.81	ENST00000367139.3 ENST00000235932.4 ENST00000437324.2 ENST00000414729.1	RAB7L1	RAB7, member RAS oncogene family-like 1
chr1_+_26869597	0.79	ENST00000530003.1	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_-_89442621	0.75	ENST00000492167.1	IGKV3-20	immunoglobulin kappa variable 3-20
chr14_+_103589789	0.72	ENST00000558056.1 ENST00000560869.1	TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr1_-_54304212	0.72	ENST00000540001.1	NDC1	NDC1 transmembrane nucleoporin
chr11_+_10476851	0.68	ENST00000396553.2	AMPD3	adenosine monophosphate deaminase 3
chr1_-_54303949	0.66	ENST00000234725.8	NDC1	NDC1 transmembrane nucleoporin
chr4_-_185395672	0.64	ENST00000393593.3	IRF2	interferon regulatory factor 2
chr19_+_10381769	0.63	ENST00000423829.2 ENST00000588645.1	ICAM1	intercellular adhesion molecule 1
chr6_+_87865262	0.62	ENST00000369577.3 ENST00000518845.1 ENST00000339907.4 ENST00000496806.2	ZNF292	zinc finger protein 292
chr11_-_72853091	0.62	ENST00000311172.7 ENST00000409314.1	FCHSD2	FCH and double SH3 domains 2
chr2_+_97203082	0.60	ENST00000454558.2	ARID5A	AT rich interactive domain 5A (MRF1-like)
chr1_-_202130702	0.60	ENST00000309017.3 ENST00000477554.1 ENST00000492451.1	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr1_-_54303934	0.58	ENST00000537333.1	NDC1	NDC1 transmembrane nucleoporin
chr1_-_236030216	0.58	ENST00000389794.3 ENST00000389793.2	LYST	lysosomal trafficking regulator
chr6_+_144471643	0.57	ENST00000367568.4	STX11	syntaxin 11
chr9_+_19230433	0.55	ENST00000434457.2 ENST00000602925.1	DENND4C	DENN/MADD domain containing 4C
chr1_+_46640750	0.54	ENST00000372003.1	TSPAN1	tetraspanin 1
chr1_+_63833261	0.53	ENST00000371108.4	ALG6	ALG6, alpha-1,3-glucosyltransferase
chr2_+_233925064	0.53	ENST00000359570.5 ENST00000538935.1	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr1_-_205744205	0.52	ENST00000446390.2	RAB7L1	RAB7, member RAS oncogene family-like 1
chr19_+_41281060	0.52	ENST00000594436.1 ENST00000597784.1	MIA	melanoma inhibitory activity
chr2_+_97202480	0.52	ENST00000357485.3	ARID5A	AT rich interactive domain 5A (MRF1-like)
chr17_-_4852332	0.52	ENST00000572383.1	PFN1	profilin 1
chr12_-_54653313	0.51	ENST00000550411.1 ENST00000439541.2	CBX5	chromobox homolog 5
chr17_+_16318909	0.51	ENST00000577397.1	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr2_+_208394616	0.50	ENST00000432329.2 ENST00000353267.3 ENST00000445803.1	CREB1	cAMP responsive element binding protein 1
chr11_-_3862206	0.50	ENST00000351018.4	RHOG	ras homolog family member G
chr1_+_101185290	0.49	ENST00000370119.4 ENST00000347652.2 ENST00000294728.2 ENST00000370115.1	VCAM1	vascular cell adhesion molecule 1
chr17_+_16318850	0.48	ENST00000338560.7	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr19_-_4831701	0.47	ENST00000248244.5	TICAM1	toll-like receptor adaptor molecule 1
chr5_+_150591678	0.47	ENST00000523466.1	GM2A	GM2 ganglioside activator
chr2_+_163175394	0.47	ENST00000446271.1 ENST00000429691.2	GCA	grancalcin, EF-hand calcium binding protein
chr1_-_65432171	0.46	ENST00000342505.4	JAK1	Janus kinase 1
chr12_+_49761273	0.46	ENST00000551540.1 ENST00000552918.1 ENST00000548777.1 ENST00000547865.1 ENST00000552171.1	SPATS2	spermatogenesis associated, serine-rich 2
chr19_-_51472031	0.45	ENST00000391808.1	KLK6	kallikrein-related peptidase 6
chr4_+_114214125	0.44	ENST00000509550.1	ANK2	ankyrin 2, neuronal
chr1_-_151319710	0.43	ENST00000290524.4 ENST00000437327.1 ENST00000452513.2 ENST00000368870.2 ENST00000452671.2	RFX5	regulatory factor X, 5 (influences HLA class II expression)
chr7_-_93520259	0.42	ENST00000222543.5	TFPI2	tissue factor pathway inhibitor 2
chr12_+_49761224	0.42	ENST00000553127.1 ENST00000321898.6	SPATS2	spermatogenesis associated, serine-rich 2
chr1_-_209824643	0.40	ENST00000391911.1 ENST00000415782.1	LAMB3	laminin, beta 3
chr7_-_93520191	0.40	ENST00000545378.1	TFPI2	tissue factor pathway inhibitor 2
chr15_+_57884086	0.39	ENST00000380569.2 ENST00000380561.2 ENST00000574161.1 ENST00000572390.1 ENST00000396180.1 ENST00000380560.2	GCOM1	GRINL1A complex locus 1
chr19_+_45251804	0.38	ENST00000164227.5	BCL3	B-cell CLL/lymphoma 3
chr4_-_174256276	0.37	ENST00000296503.5	HMGB2	high mobility group box 2
chr12_+_5019061	0.37	ENST00000382545.3	KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr22_-_28315115	0.36	ENST00000455418.3 ENST00000436663.1 ENST00000320996.10 ENST00000335272.5	PITPNB	phosphatidylinositol transfer protein, beta
chr20_+_18488528	0.36	ENST00000377465.1	SEC23B	Sec23 homolog B (S. cerevisiae)
chr8_-_70747205	0.36	ENST00000260126.4	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chr15_+_57884199	0.36	ENST00000587652.1 ENST00000380568.3 ENST00000380565.4 ENST00000380563.2	GCOM1 MYZAP POLR2M	GRINL1A complex locus 1 myocardial zonula adherens protein polymerase (RNA) II (DNA directed) polypeptide M
chr18_-_12884259	0.36	ENST00000353319.4 ENST00000327283.3	PTPN2	protein tyrosine phosphatase, non-receptor type 2
chr12_-_56727487	0.35	ENST00000548043.1 ENST00000425394.2	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr12_-_28124903	0.35	ENST00000395872.1 ENST00000354417.3 ENST00000201015.4	PTHLH	parathyroid hormone-like hormone
chr10_+_12391685	0.34	ENST00000378845.1	CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr3_-_49131473	0.34	ENST00000430979.1 ENST00000357496.2 ENST00000437939.1	QRICH1	glutamine-rich 1
chr2_+_208394658	0.33	ENST00000421139.1	CREB1	cAMP responsive element binding protein 1
chr5_+_133984462	0.33	ENST00000398844.2 ENST00000322887.4	SEC24A	SEC24 family member A
chr6_-_30712313	0.32	ENST00000376377.2 ENST00000259874.5	IER3	immediate early response 3
chr11_-_790060	0.32	ENST00000330106.4	CEND1	cell cycle exit and neuronal differentiation 1
chr4_-_151936416	0.31	ENST00000510413.1 ENST00000507224.1	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr1_-_209979375	0.31	ENST00000367021.3	IRF6	interferon regulatory factor 6
chr2_+_208394455	0.30	ENST00000430624.1	CREB1	cAMP responsive element binding protein 1
chr2_+_44396000	0.29	ENST00000409895.4 ENST00000409432.3 ENST00000282412.4 ENST00000378551.2 ENST00000345249.4	PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr13_-_52027134	0.29	ENST00000311234.4 ENST00000425000.1 ENST00000463928.1 ENST00000442263.3 ENST00000398119.2	INTS6	integrator complex subunit 6
chr1_-_41950342	0.29	ENST00000372587.4	EDN2	endothelin 2
chr21_+_34775181	0.27	ENST00000290219.6	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr5_+_140787600	0.27	ENST00000520790.1	PCDHGB6	protocadherin gamma subfamily B, 6
chr12_+_53662073	0.27	ENST00000553219.1 ENST00000257934.4	ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)
chr12_-_49259643	0.27	ENST00000309739.5	RND1	Rho family GTPase 1
chr11_-_128392085	0.25	ENST00000526145.2 ENST00000531611.1 ENST00000319397.6 ENST00000345075.4 ENST00000535549.1	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr1_-_202129105	0.25	ENST00000367279.4	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr10_+_13141585	0.25	ENST00000378764.2	OPTN	optineurin
chr21_+_34775698	0.24	ENST00000381995.1	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_+_82187630	0.24	ENST00000265284.6	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_-_56727676	0.24	ENST00000547572.1 ENST00000257931.5 ENST00000440411.3	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_+_208394794	0.24	ENST00000536726.1 ENST00000374397.4 ENST00000452474.1	CREB1	cAMP responsive element binding protein 1
chr18_+_3252265	0.24	ENST00000580887.1 ENST00000536605.1	MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric
chr4_+_140222609	0.24	ENST00000296543.5 ENST00000398947.1	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr20_+_18488137	0.23	ENST00000450074.1 ENST00000262544.2 ENST00000336714.3 ENST00000377475.3	SEC23B	Sec23 homolog B (S. cerevisiae)
chr9_+_82187487	0.22	ENST00000435650.1 ENST00000414465.1 ENST00000376537.4 ENST00000376534.4	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr5_-_141257954	0.22	ENST00000456271.1 ENST00000394536.3 ENST00000503492.1 ENST00000287008.3	PCDH1	protocadherin 1
chr13_+_47127322	0.21	ENST00000389798.3	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1
chr7_+_143013198	0.21	ENST00000343257.2	CLCN1	chloride channel, voltage-sensitive 1
chr11_-_6633799	0.20	ENST00000299424.4	TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr21_+_34775772	0.20	ENST00000405436.1	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_+_36572851	0.20	ENST00000298048.2 ENST00000538311.1 ENST00000536987.1 ENST00000545008.1 ENST00000536860.1 ENST00000536329.1 ENST00000541717.1 ENST00000543751.1	MELK	maternal embryonic leucine zipper kinase
chr10_+_22605304	0.20	ENST00000475460.2 ENST00000602390.1 ENST00000489125.2 ENST00000456711.1 ENST00000444869.1	COMMD3-BMI1 COMMD3	COMMD3-BMI1 readthrough COMM domain containing 3
chr11_-_66313699	0.19	ENST00000526986.1 ENST00000310442.3	ZDHHC24	zinc finger, DHHC-type containing 24
chr2_+_203776937	0.19	ENST00000402905.3 ENST00000414490.1 ENST00000431787.1 ENST00000444724.1 ENST00000414857.1 ENST00000430899.1 ENST00000445120.1 ENST00000441569.1 ENST00000432024.1 ENST00000443740.1 ENST00000414439.1 ENST00000428585.1 ENST00000545253.1 ENST00000545262.1 ENST00000447539.1 ENST00000456821.2 ENST00000434998.1 ENST00000320443.8	CARF	calcium responsive transcription factor
chr19_-_51471362	0.18	ENST00000376853.4 ENST00000424910.2	KLK6	kallikrein-related peptidase 6
chr10_+_22605374	0.17	ENST00000448361.1	COMMD3	COMM domain containing 3
chr4_+_74735102	0.17	ENST00000395761.3	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr7_-_16844611	0.17	ENST00000401412.1 ENST00000419304.2	AGR2	anterior gradient 2
chr12_+_53662110	0.16	ENST00000552462.1	ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)
chr14_+_22984601	0.15	ENST00000390509.1	TRAJ28	T cell receptor alpha joining 28
chr6_-_136847099	0.15	ENST00000438100.2	MAP7	microtubule-associated protein 7
chr1_-_202129704	0.15	ENST00000476061.1 ENST00000544762.1 ENST00000467283.1 ENST00000464870.1 ENST00000435759.2 ENST00000486116.1 ENST00000543735.1 ENST00000308986.5 ENST00000477625.1	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr2_-_136743039	0.15	ENST00000537273.1	DARS	aspartyl-tRNA synthetase
chr3_+_5163905	0.14	ENST00000256496.3 ENST00000419534.2	ARL8B	ADP-ribosylation factor-like 8B
chr10_+_74870253	0.14	ENST00000544879.1 ENST00000537969.1 ENST00000372997.3	NUDT13	nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr15_-_71055878	0.14	ENST00000322954.6	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr6_-_30710510	0.13	ENST00000376389.3	FLOT1	flotillin 1
chr22_+_41347363	0.13	ENST00000216225.8	RBX1	ring-box 1, E3 ubiquitin protein ligase
chr14_+_24439148	0.12	ENST00000543805.1 ENST00000534993.1	DHRS4L2	dehydrogenase/reductase (SDR family) member 4 like 2
chr10_+_74870206	0.12	ENST00000357321.4 ENST00000349051.5	NUDT13	nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr11_-_44331679	0.12	ENST00000329255.3	ALX4	ALX homeobox 4
chr1_-_1822495	0.12	ENST00000378609.4	GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1
chr1_-_155658085	0.12	ENST00000311573.5 ENST00000438245.2	YY1AP1	YY1 associated protein 1
chr19_-_51471381	0.12	ENST00000594641.1	KLK6	kallikrein-related peptidase 6
chr9_+_82188077	0.11	ENST00000425506.1	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr16_+_67282853	0.11	ENST00000299798.11	SLC9A5	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr12_-_57504069	0.10	ENST00000543873.2 ENST00000554663.1 ENST00000557635.1	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr5_+_112312416	0.09	ENST00000389063.2	DCP2	decapping mRNA 2
chr3_+_141205852	0.09	ENST00000286364.3 ENST00000452898.1	RASA2	RAS p21 protein activator 2
chr1_-_203274418	0.09	ENST00000457348.1	RP11-134P9.1	long intergenic non-protein coding RNA 1136
chr11_+_18287801	0.09	ENST00000532858.1 ENST00000405158.2	SAA1	serum amyloid A1
chr18_-_31802282	0.09	ENST00000535475.1	NOL4	nucleolar protein 4
chr2_+_162016916	0.09	ENST00000405852.1	TANK	TRAF family member-associated NFKB activator
chr11_+_65190245	0.08	ENST00000499732.1 ENST00000501122.2 ENST00000601801.1	NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.4	21.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.4	8.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	3.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	6.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	2.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	5.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.9	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1	3.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	3.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	4.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	5.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	3.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	2.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	2.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	5.9	GO:0042289	MHC class II protein binding(GO:0042289)
1.0	4.1	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.9	9.4	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.9	11.5	GO:0032395	MHC class II receptor activity(GO:0032395)
0.8	4.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.7	4.0	GO:0046979	TAP2 binding(GO:0046979)
0.6	3.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.3	3.6	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.3	13.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	3.2	GO:0008199	ferric iron binding(GO:0008199)
0.2	10.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2	1.7	GO:0019863	IgE binding(GO:0019863)
0.2	1.5	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.2	0.5	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2	1.4	GO:1990763	arrestin family protein binding(GO:1990763)
0.2	1.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.2	2.6	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.7	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.1	1.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1	0.4	GO:0097677	STAT family protein binding(GO:0097677)
0.1	1.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	5.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	2.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	1.8	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	1.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	3.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	2.9	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.4	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.1	3.9	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	1.8	GO:0070628	proteasome binding(GO:0070628)
0.1	0.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	2.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.7	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	2.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.9	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.5	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.3	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	2.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.9	GO:0043422	protein kinase B binding(GO:0043422)
0.1	1.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	1.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	1.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.5	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	2.5	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	6.5	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.3	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.6	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	13.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.8	5.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.7	2.0	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.6	11.5	GO:0042613	MHC class II protein complex(GO:0042613)
0.5	5.7	GO:0042612	MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.5	3.6	GO:0019815	B cell receptor complex(GO:0019815)
0.5	3.3	GO:0043196	varicosity(GO:0043196)
0.4	2.5	GO:0032584	growth cone membrane(GO:0032584)
0.2	0.7	GO:0071746	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.2	1.7	GO:0005610	laminin-5 complex(GO:0005610)
0.2	0.6	GO:0031251	PAN complex(GO:0031251)
0.2	1.4	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.2	2.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	0.5	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1	0.5	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1	1.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	4.7	GO:0097542	ciliary tip(GO:0097542)
0.1	0.5	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	4.9	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0	0.9	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	13.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	1.9	GO:0002102	podosome(GO:0002102)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.7	GO:0000145	exocyst(GO:0000145)
0.0	1.9	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0031415	NatA complex(GO:0031415)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	1.4	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	1.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	9.5	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	2.4	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	1.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	1.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.6	GO:0031594	neuromuscular junction(GO:0031594)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.7	GO:1990108	protein linear deubiquitination(GO:1990108)
1.6	4.7	GO:0034146	B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
1.4	1.4	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.3	3.9	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3	3.8	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
1.2	10.7	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
1.2	5.9	GO:0002905	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.8	3.1	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
0.8	3.8	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.8	2.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.8	6.0	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.7	2.8	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.7	4.9	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.7	3.3	GO:0033590	response to cobalamin(GO:0033590)
0.7	2.0	GO:0051300	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.6	3.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.6	2.4	GO:0072183	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.6	5.2	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.6	5.7	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.6	2.8	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.5	2.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.4	6.7	GO:0060263	regulation of respiratory burst(GO:0060263)
0.4	2.6	GO:0016554	cytidine to uridine editing(GO:0016554)
0.4	3.2	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.4	1.2	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.4	1.9	GO:0070842	aggresome assembly(GO:0070842)
0.4	1.1	GO:1904897	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4	7.0	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.4	1.5	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of macrophage apoptotic process(GO:2000110)
0.3	2.6	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.3	3.6	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3	2.4	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3	4.5	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.2	1.2	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.2	0.5	GO:0045359	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2	1.4	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.2	0.8	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	0.6	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.2	1.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.2	0.5	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2	0.9	GO:0007296	vitellogenesis(GO:0007296)
0.2	1.4	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.1	1.6	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.1	0.4	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1	0.3	GO:0060584	positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.4	GO:0051685	maintenance of ER location(GO:0051685)
0.1	14.0	GO:0031295	T cell costimulation(GO:0031295)
0.1	0.7	GO:0006196	AMP catabolic process(GO:0006196)
0.1	2.7	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.4	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1	0.5	GO:0050821	protein stabilization(GO:0050821)
0.1	1.7	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	2.6	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.1	0.7	GO:0051601	exocyst localization(GO:0051601)
0.1	0.3	GO:0021590	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.1	0.5	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	1.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.5	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.3	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.9	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.2	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.3	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	2.7	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.0	3.7	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.4	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.2	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.4	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.0	0.8	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.2	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	2.9	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.7	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.5	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0002295	T-helper cell lineage commitment(GO:0002295)
0.0	0.9	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.3	GO:1904996	PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0	0.8	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.0	0.7	GO:0003094	glomerular filtration(GO:0003094)
0.0	0.6	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	1.5	GO:0090003	regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.7	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.3	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.4	GO:0016180	snRNA processing(GO:0016180)
0.0	0.2	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	1.0	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	3.1	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	1.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.9	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.5	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.6	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.3	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0097190	apoptotic signaling pathway(GO:0097190)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	26.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	2.8	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.2	1.6	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	3.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	3.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	4.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	6.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	6.8	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	2.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	3.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	2.6	PID EPO PATHWAY	EPO signaling pathway
0.1	3.4	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	3.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	1.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	3.2	PID BCR 5PATHWAY	BCR signaling pathway
0.1	1.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	2.7	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	1.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.4	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.3	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling