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ENCODE cell lines, expression (Ernst 2011)

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Results for RFX3_RFX2

Z-value: 1.59

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Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
RFX3
ENSG00000080298.11 RFX3
RFX2
ENSG00000087903.8 RFX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg19_v2_chr19_-_6110474_61105510.175.3e-01Click!
RFX3hg19_v2_chr9_-_3525968_3526016-0.058.5e-01Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_133938820 6.76 ENST00000299106.4
ENST00000529443.2
 JAM3
 junctional adhesion molecule 3
chr11_+_133938955 6.17 ENST00000534549.1
ENST00000441717.3
 JAM3
 junctional adhesion molecule 3
chr2_-_175870085 4.46 ENST00000409156.3
 CHN1
 chimerin 1
chr2_-_175869936 4.13 ENST00000409900.3
 CHN1
 chimerin 1
chr10_-_126694575 3.35 ENST00000334808.6
 CTBP2
 C-terminal binding protein 2
chrX_+_135251783 3.29 ENST00000394153.2
 FHL1
 four and a half LIM domains 1
chr14_+_105941118 2.83 ENST00000550577.1
ENST00000538259.2
 CRIP2
 cysteine-rich protein 2
chr15_+_43803143 2.72 ENST00000382031.1
 MAP1A
 microtubule-associated protein 1A
chr17_-_64187973 2.62 ENST00000583358.1
ENST00000392769.2
 CEP112
 centrosomal protein 112kDa
chr17_-_64188177 2.57 ENST00000535342.2
 CEP112
 centrosomal protein 112kDa
chr3_-_149688896 2.55 ENST00000239940.7
 PFN2
 profilin 2
chr14_-_74181106 2.55 ENST00000316836.3
 PNMA1
 paraneoplastic Ma antigen 1
chrX_+_135252050 2.45 ENST00000449474.1
ENST00000345434.3
 FHL1
 four and a half LIM domains 1
chr19_-_58609570 2.15 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
 ZSCAN18
 zinc finger and SCAN domain containing 18
chrX_+_135251835 2.12 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr11_+_844406 2.08 ENST00000397404.1
 TSPAN4
 tetraspanin 4
chr17_-_76899275 2.03 ENST00000322630.2
ENST00000586713.1
 DDC8
 Protein DDC8 homolog
chr20_+_43160458 1.89 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
 PKIG
 protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr20_+_43160409 1.87 ENST00000372894.3
ENST00000372892.3
ENST00000372891.3
 PKIG
 protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr14_+_100259666 1.81 ENST00000262233.6
ENST00000334192.4
 EML1
 echinoderm microtubule associated protein like 1
chr6_+_52285131 1.73 ENST00000433625.2
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr15_+_96873921 1.61 ENST00000394166.3
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr6_+_52285046 1.59 ENST00000371068.5
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr15_+_71184931 1.57 ENST00000560369.1
ENST00000260382.5
 LRRC49
 leucine rich repeat containing 49
chr5_-_179780312 1.51 ENST00000253778.8
 GFPT2
 glutamine-fructose-6-phosphate transaminase 2
chrX_+_103173457 1.49 ENST00000419165.1
 TMSB15B
 thymosin beta 15B
chr2_+_170335924 1.48 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
 BBS5
RP11-724O16.1
 Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr16_+_57279248 1.44 ENST00000562023.1
ENST00000563234.1
 ARL2BP
 ADP-ribosylation factor-like 2 binding protein
chr15_+_71185148 1.41 ENST00000443425.2
ENST00000560755.1
 LRRC49
 leucine rich repeat containing 49
chr7_-_35077653 1.38 ENST00000310974.4
 DPY19L1
 dpy-19-like 1 (C. elegans)
chr1_+_84630053 1.38 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr1_-_169337176 1.36 ENST00000472647.1
ENST00000367811.3
 NME7
 NME/NM23 family member 7
chr1_+_84630645 1.35 ENST00000394839.2
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr8_+_59465728 1.34 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
 SDCBP
 syndecan binding protein (syntenin)
chr9_-_130635741 1.33 ENST00000223836.10
 AK1
 adenylate kinase 1
chr5_-_16742330 1.28 ENST00000505695.1
ENST00000427430.2
 MYO10
 myosin X
chr14_-_102771462 1.23 ENST00000522874.1
 MOK
 MOK protein kinase
chr3_-_107941230 1.22 ENST00000264538.3
 IFT57
 intraflagellar transport 57 homolog (Chlamydomonas)
chr22_+_39052632 1.22 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
 CBY1
 chibby homolog 1 (Drosophila)
chr15_-_43802769 1.19 ENST00000263801.3
 TP53BP1
 tumor protein p53 binding protein 1
chr8_-_98290087 1.18 ENST00000322128.3
 TSPYL5
 TSPY-like 5
chr6_-_116575226 1.17 ENST00000420283.1
 TSPYL4
 TSPY-like 4
chr14_-_102771516 1.15 ENST00000524214.1
ENST00000193029.6
ENST00000361847.2
 MOK
 MOK protein kinase
chr6_-_43484718 1.14 ENST00000372422.2
 YIPF3
 Yip1 domain family, member 3
chr22_-_43485381 1.13 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
 TTLL1
 tubulin tyrosine ligase-like family, member 1
chr16_-_88923285 1.11 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
 GALNS
 galactosamine (N-acetyl)-6-sulfate sulfatase
chr16_+_57279004 1.10 ENST00000219204.3
 ARL2BP
 ADP-ribosylation factor-like 2 binding protein
chr17_+_26662730 1.04 ENST00000226225.2
 TNFAIP1
 tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_59249732 1.04 ENST00000371222.2
 JUN
 jun proto-oncogene
chr2_+_232063260 1.01 ENST00000349938.4
 ARMC9
 armadillo repeat containing 9
chr14_-_24664776 0.98 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
 TM9SF1
 transmembrane 9 superfamily member 1
chr11_+_102980126 0.98 ENST00000375735.2
 DYNC2H1
 dynein, cytoplasmic 2, heavy chain 1
chr6_-_43484621 0.98 ENST00000506469.1
ENST00000503972.1
 YIPF3
 Yip1 domain family, member 3
chr19_-_47354082 0.96 ENST00000593442.1
ENST00000263270.6
 AP2S1
 adaptor-related protein complex 2, sigma 1 subunit
chr1_-_114302086 0.96 ENST00000369604.1
ENST00000357783.2
 PHTF1
 putative homeodomain transcription factor 1
chr5_+_148521381 0.94 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr1_+_38022572 0.94 ENST00000541606.1
 DNALI1
 dynein, axonemal, light intermediate chain 1
chr11_-_67276100 0.93 ENST00000301488.3
 CDK2AP2
 cyclin-dependent kinase 2 associated protein 2
chr3_-_49055991 0.93 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
 DALRD3
 DALR anticodon binding domain containing 3
chr1_-_114301755 0.90 ENST00000393357.2
ENST00000369596.2
ENST00000446739.1
 PHTF1
 putative homeodomain transcription factor 1
chr12_-_131323754 0.86 ENST00000261653.6
 STX2
 syntaxin 2
chr5_+_121647764 0.85 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
 SNCAIP
 synuclein, alpha interacting protein
chr5_+_121647924 0.84 ENST00000414317.2
 SNCAIP
 synuclein, alpha interacting protein
chr3_-_58563094 0.84 ENST00000464064.1
 FAM107A
 family with sequence similarity 107, member A
chr14_-_24664540 0.84 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
 TM9SF1
 transmembrane 9 superfamily member 1
chr11_+_66278080 0.83 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
 BBS1
 Bardet-Biedl syndrome 1
chr1_-_114301960 0.83 ENST00000369598.1
ENST00000369600.1
 PHTF1
 putative homeodomain transcription factor 1
chr10_+_70748487 0.83 ENST00000361983.4
 KIAA1279
 KIAA1279
chr3_+_158288999 0.83 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
 MLF1
 myeloid leukemia factor 1
chr11_+_102980251 0.83 ENST00000334267.7
ENST00000398093.3
 DYNC2H1
 dynein, cytoplasmic 2, heavy chain 1
chr11_-_6426635 0.83 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
 APBB1
 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_-_47354023 0.83 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
 AP2S1
 adaptor-related protein complex 2, sigma 1 subunit
chr5_+_121647877 0.82 ENST00000514497.2
ENST00000261367.7
 SNCAIP
 synuclein, alpha interacting protein
chr15_-_55700457 0.82 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
 CCPG1
 cell cycle progression 1
chr14_-_23058063 0.81 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
 DAD1
 defender against cell death 1
chr8_+_120428546 0.80 ENST00000259526.3
 NOV
 nephroblastoma overexpressed
chr5_+_92919043 0.80 ENST00000327111.3
 NR2F1
 nuclear receptor subfamily 2, group F, member 1
chr11_-_64546202 0.77 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
 SF1
 splicing factor 1
chr4_-_186733363 0.76 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2
 sorbin and SH3 domain containing 2
chr17_+_26662597 0.74 ENST00000544907.2
 TNFAIP1
 tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr19_+_3572758 0.73 ENST00000416526.1
 HMG20B
 high mobility group 20B
chr15_-_55700216 0.72 ENST00000569205.1
 CCPG1
 cell cycle progression 1
chr1_-_48937838 0.72 ENST00000371847.3
 SPATA6
 spermatogenesis associated 6
chr1_-_48937821 0.71 ENST00000396199.3
 SPATA6
 spermatogenesis associated 6
chr14_+_74486043 0.71 ENST00000464394.1
ENST00000394009.3
 CCDC176
 coiled-coil domain containing 176
chr1_-_109584768 0.71 ENST00000357672.3
 WDR47
 WD repeat domain 47
chr1_-_109584716 0.71 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
 WDR47
 WD repeat domain 47
chr13_+_37005967 0.69 ENST00000440264.1
ENST00000449823.1
 CCNA1
 cyclin A1
chr19_-_46974741 0.68 ENST00000313683.10
ENST00000602246.1
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr10_-_17659234 0.68 ENST00000466335.1
 PTPLA
 protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr14_+_74416989 0.68 ENST00000334571.2
ENST00000554920.1
 COQ6
 coenzyme Q6 monooxygenase
chr19_-_46974664 0.67 ENST00000438932.2
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr12_-_131323719 0.67 ENST00000392373.2
 STX2
 syntaxin 2
chr12_+_9067123 0.66 ENST00000543824.1
 PHC1
 polyhomeotic homolog 1 (Drosophila)
chr19_-_47353547 0.66 ENST00000601498.1
 AP2S1
 adaptor-related protein complex 2, sigma 1 subunit
chr11_+_17298297 0.66 ENST00000529010.1
 NUCB2
 nucleobindin 2
chr2_-_44588893 0.66 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
 PREPL
 prolyl endopeptidase-like
chr1_-_183604794 0.65 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
 ARPC5
 actin related protein 2/3 complex, subunit 5, 16kDa
chr4_-_156298028 0.64 ENST00000433024.1
ENST00000379248.2
 MAP9
 microtubule-associated protein 9
chr19_+_9945962 0.64 ENST00000587625.1
ENST00000247970.4
ENST00000588695.1
 PIN1
 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
chr7_+_100273736 0.63 ENST00000412215.1
ENST00000393924.1
 GNB2
 guanine nucleotide binding protein (G protein), beta polypeptide 2
chr6_+_31939608 0.63 ENST00000375331.2
ENST00000375333.2
 STK19
 serine/threonine kinase 19
chr5_+_72112470 0.63 ENST00000447967.2
ENST00000523768.1
 TNPO1
 transportin 1
chr14_-_75643296 0.62 ENST00000303575.4
 TMED10
 transmembrane emp24-like trafficking protein 10 (yeast)
chr1_-_109584608 0.62 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
 WDR47
 WD repeat domain 47
chr9_+_132815985 0.61 ENST00000372410.3
 GPR107
 G protein-coupled receptor 107
chr15_-_55700522 0.60 ENST00000564092.1
ENST00000310958.6
 CCPG1
 cell cycle progression 1
chr1_+_169337172 0.60 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
 BLZF1
 basic leucine zipper nuclear factor 1
chr3_-_49761337 0.60 ENST00000535833.1
ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
 AMIGO3
GMPPB
 adhesion molecule with Ig-like domain 3
GDP-mannose pyrophosphorylase B
chr17_-_26662440 0.59 ENST00000578122.1
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr12_+_9067327 0.59 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
 PHC1
 polyhomeotic homolog 1 (Drosophila)
chr19_+_3572925 0.59 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
 HMG20B
 high mobility group 20B
chr19_-_15560730 0.58 ENST00000389282.4
ENST00000263381.7
 WIZ
 widely interspaced zinc finger motifs
chr4_-_156297949 0.57 ENST00000515654.1
 MAP9
 microtubule-associated protein 9
chr2_+_183580954 0.57 ENST00000264065.7
 DNAJC10
 DnaJ (Hsp40) homolog, subfamily C, member 10
chr11_+_17298255 0.57 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
 NUCB2
 nucleobindin 2
chr1_+_38022513 0.56 ENST00000296218.7
 DNALI1
 dynein, axonemal, light intermediate chain 1
chr16_+_19729586 0.56 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
 IQCK
 IQ motif containing K
chr6_+_30035307 0.55 ENST00000376765.2
ENST00000376763.1
 PPP1R11
 protein phosphatase 1, regulatory (inhibitor) subunit 11
chr2_-_44588624 0.54 ENST00000438314.1
ENST00000409936.1
 PREPL
 prolyl endopeptidase-like
chr6_+_30034865 0.53 ENST00000376772.3
 PPP1R11
 protein phosphatase 1, regulatory (inhibitor) subunit 11
chrX_+_129473916 0.52 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_-_48937682 0.52 ENST00000371843.3
 SPATA6
 spermatogenesis associated 6
chr1_+_183605200 0.51 ENST00000304685.4
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr4_+_87515454 0.50 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
 PTPN13
 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr17_+_2240775 0.50 ENST00000268989.3
ENST00000426855.2
 SGSM2
 small G protein signaling modulator 2
chr11_+_111807863 0.50 ENST00000440460.2
 DIXDC1
 DIX domain containing 1
chr12_+_4671352 0.50 ENST00000542744.1
 DYRK4
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr3_+_158288960 0.50 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
 MLF1
 myeloid leukemia factor 1
chr21_-_35014027 0.50 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
 CRYZL1
 crystallin, zeta (quinone reductase)-like 1
chr1_+_203444887 0.50 ENST00000343110.2
 PRELP
 proline/arginine-rich end leucine-rich repeat protein
chr7_-_44229022 0.50 ENST00000403799.3
 GCK
 glucokinase (hexokinase 4)
chr6_+_30034966 0.50 ENST00000376769.2
 PPP1R11
 protein phosphatase 1, regulatory (inhibitor) subunit 11
chr10_-_17243579 0.50 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
 TRDMT1
 tRNA aspartic acid methyltransferase 1
chr5_+_72112418 0.49 ENST00000454282.1
 TNPO1
 transportin 1
chr12_+_120933859 0.49 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
 DYNLL1
 dynein, light chain, LC8-type 1
chr13_+_38923959 0.49 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
 UFM1
 ubiquitin-fold modifier 1
chr14_+_102829300 0.49 ENST00000359520.7
 TECPR2
 tectonin beta-propeller repeat containing 2
chr17_+_41322483 0.48 ENST00000341165.6
ENST00000586650.1
ENST00000422280.1
 NBR1
 neighbor of BRCA1 gene 1
chr2_-_44588679 0.48 ENST00000409411.1
 PREPL
 prolyl endopeptidase-like
chr8_+_22462532 0.48 ENST00000389279.3
 CCAR2
 cell cycle and apoptosis regulator 2
chr14_+_75469606 0.47 ENST00000266126.5
 EIF2B2
 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
chr17_-_56084578 0.47 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
 SRSF1
 serine/arginine-rich splicing factor 1
chr8_-_101964231 0.46 ENST00000521309.1
 YWHAZ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr16_+_57662419 0.45 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
 GPR56
 G protein-coupled receptor 56
chr22_-_36357671 0.45 ENST00000408983.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr17_-_26662464 0.45 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
 IFT20
 intraflagellar transport 20 homolog (Chlamydomonas)
chr4_-_156298087 0.44 ENST00000311277.4
 MAP9
 microtubule-associated protein 9
chr19_-_2783363 0.44 ENST00000221566.2
 SGTA
 small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr1_-_159893507 0.44 ENST00000368096.1
 TAGLN2
 transgelin 2
chrX_+_129473859 0.44 ENST00000424447.1
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_+_99699280 0.43 ENST00000421755.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr3_-_52739762 0.43 ENST00000487642.1
ENST00000464705.1
ENST00000491606.1
ENST00000489119.1
ENST00000478968.2
 GLT8D1
 glycosyltransferase 8 domain containing 1
chr2_-_44588694 0.43 ENST00000409957.1
 PREPL
 prolyl endopeptidase-like
chr9_-_110251836 0.43 ENST00000374672.4
 KLF4
 Kruppel-like factor 4 (gut)
chr3_+_14166440 0.42 ENST00000306077.4
 TMEM43
 transmembrane protein 43
chr12_+_120933904 0.42 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
 DYNLL1
 dynein, light chain, LC8-type 1
chr19_+_13842559 0.42 ENST00000586600.1
 CCDC130
 coiled-coil domain containing 130
chr3_+_49027308 0.42 ENST00000383729.4
ENST00000343546.4
 P4HTM
 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr17_-_61523535 0.42 ENST00000584031.1
ENST00000392976.1
 CYB561
 cytochrome b561
chr13_+_37006421 0.41 ENST00000255465.4
 CCNA1
 cyclin A1
chr16_+_3550924 0.40 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
 CLUAP1
 clusterin associated protein 1
chr1_-_44820880 0.40 ENST00000372257.2
ENST00000457571.1
ENST00000452396.1
 ERI3
 ERI1 exoribonuclease family member 3
chr17_+_66508154 0.40 ENST00000358598.2
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chrX_-_102941596 0.39 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
 MORF4L2
 mortality factor 4 like 2
chr3_-_121468513 0.39 ENST00000494517.1
ENST00000393667.3
 GOLGB1
 golgin B1
chr20_-_20033052 0.39 ENST00000536226.1
 CRNKL1
 crooked neck pre-mRNA splicing factor 1
chr6_-_32145861 0.39 ENST00000336984.6
 AGPAT1
 1-acylglycerol-3-phosphate O-acyltransferase 1
chr15_+_72978539 0.38 ENST00000539603.1
ENST00000569338.1
 BBS4
 Bardet-Biedl syndrome 4
chr1_+_203595903 0.38 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
chr7_+_99699179 0.38 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr6_-_135818844 0.38 ENST00000524469.1
ENST00000367800.4
ENST00000327035.6
ENST00000457866.2
ENST00000265602.6
 AHI1
 Abelson helper integration site 1
chr8_+_22462145 0.38 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
 CCAR2
 cell cycle and apoptosis regulator 2
chr14_+_57046530 0.38 ENST00000536419.1
ENST00000538838.1
 TMEM260
 transmembrane protein 260
chr10_-_119806085 0.38 ENST00000355624.3
 RAB11FIP2
 RAB11 family interacting protein 2 (class I)
chr13_+_37006398 0.37 ENST00000418263.1
 CCNA1
 cyclin A1
chr19_+_36605850 0.37 ENST00000221855.3
 TBCB
 tubulin folding cofactor B
chr20_-_44540686 0.37 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
 PLTP
 phospholipid transfer protein
chr7_-_45128472 0.37 ENST00000490531.2
 NACAD
 NAC alpha domain containing
chr11_-_64545941 0.37 ENST00000377387.1
 SF1
 splicing factor 1
chr11_+_61447845 0.37 ENST00000257215.5
 DAGLA
 diacylglycerol lipase, alpha
chr1_-_217804377 0.36 ENST00000366935.3
ENST00000366934.3
 GPATCH2
 G patch domain containing 2
chr15_+_72978521 0.36 ENST00000542334.1
ENST00000268057.4
 BBS4
 Bardet-Biedl syndrome 4
chr7_+_106685079 0.35 ENST00000265717.4
 PRKAR2B
 protein kinase, cAMP-dependent, regulatory, type II, beta
chr3_-_52740012 0.35 ENST00000407584.3
ENST00000266014.5
 GLT8D1
 glycosyltransferase 8 domain containing 1
chr2_-_47403642 0.35 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
 CALM2
 calmodulin 2 (phosphorylase kinase, delta)
chr2_+_237994519 0.35 ENST00000392008.2
ENST00000409334.1
ENST00000409629.1
 COPS8
 COP9 signalosome subunit 8
chr12_-_49351228 0.35 ENST00000541959.1
ENST00000447318.2
 ARF3
 ADP-ribosylation factor 3
chr15_-_43785303 0.35 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
 TP53BP1
 tumor protein p53 binding protein 1
chr7_+_100797726 0.34 ENST00000429457.1
 AP1S1
 adaptor-related protein complex 1, sigma 1 subunit
chr12_+_53693466 0.33 ENST00000267103.5
ENST00000548632.1
 C12orf10
 chromosome 12 open reading frame 10
chr7_+_150929550 0.33 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
 CHPF2
 chondroitin polymerizing factor 2
chr17_-_4167142 0.33 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
 ANKFY1
 ankyrin repeat and FYVE domain containing 1
chr17_+_66508537 0.33 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_-_114301503 0.33 ENST00000447664.2
 PHTF1
 putative homeodomain transcription factor 1
chr10_-_120101804 0.32 ENST00000369183.4
ENST00000369172.4
 FAM204A
 family with sequence similarity 204, member A
chr1_+_203595689 0.32 ENST00000357681.5
 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
chr19_-_50370509 0.32 ENST00000596014.1
 PNKP
 polynucleotide kinase 3'-phosphatase
chr3_-_121468602 0.32 ENST00000340645.5
 GOLGB1
 golgin B1
chr1_+_203651937 0.32 ENST00000341360.2
 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 12.9 GO:0033010 paranodal junction(GO:0033010)
0.5 1.9 GO:0097224 sperm connecting piece(GO:0097224)
0.4 5.2 GO:0060077 inhibitory synapse(GO:0060077)
0.3 1.0 GO:1902636 kinociliary basal body(GO:1902636)
0.3 3.1 GO:0034464 BBSome(GO:0034464)
0.3 1.5 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.3 0.9 GO:0044609 DBIRD complex(GO:0044609)
0.3 3.5 GO:0097470 ribbon synapse(GO:0097470)
0.2 3.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 4.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.5 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.0 GO:0035976 AP1 complex(GO:0035976)
0.1 2.4 GO:0036020 endolysosome membrane(GO:0036020)
0.1 2.4 GO:0097546 ciliary base(GO:0097546)
0.1 1.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.8 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 2.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 3.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.3 GO:0005869 dynactin complex(GO:0005869)
0.1 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.4 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 3.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.6 GO:0031201 SNARE complex(GO:0031201)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 2.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 14.7 GO:0005925 focal adhesion(GO:0005925)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 3.6 GO:0005874 microtubule(GO:0005874)
0.0 1.4 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 4.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 12.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 8.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 13.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.6 3.1 GO:0097338 response to clozapine(GO:0097338)
0.5 1.4 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 2.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.4 1.6 GO:0009956 radial pattern formation(GO:0009956)
0.4 3.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3 1.0 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 0.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 4.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 0.8 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3 1.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 0.8 GO:1990523 bone regeneration(GO:1990523)
0.3 1.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 8.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 0.7 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 1.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 2.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 2.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 1.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 0.9 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 0.4 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.2 1.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.2 0.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 0.6 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 5.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.4 GO:0071409 negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.1 7.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 2.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.6 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 1.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 1.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.4 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 2.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 1.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 2.8 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 2.0 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 3.8 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.1 0.9 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.5 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 2.1 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.7 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.1 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.2 GO:0070213 negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 1.5 GO:0007141 male meiosis I(GO:0007141)
0.1 0.2 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.6 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 3.0 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.1 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 2.1 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.7 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.0 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.2 GO:1902903 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) regulation of fibril organization(GO:1902903) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 1.7 GO:0006914 autophagy(GO:0006914)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 1.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.5 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:1903305 regulation of calcium ion-dependent exocytosis(GO:0017158) regulation of regulated secretory pathway(GO:1903305)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 1.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 1.6 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.0 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 1.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.3 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.8 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.4 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.0 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0050774 manganese ion transport(GO:0006828) negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 7.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.7 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 4.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 1.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.3 1.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 0.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 1.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.3 1.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 4.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 1.0 GO:0002046 opsin binding(GO:0002046)
0.2 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 0.6 GO:0070984 SET domain binding(GO:0070984)
0.2 2.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 0.7 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 1.9 GO:0032027 myosin light chain binding(GO:0032027)
0.2 8.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.1 0.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.6 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.8 GO:0005119 smoothened binding(GO:0005119)
0.1 2.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 1.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 2.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 1.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 14.9 GO:0005178 integrin binding(GO:0005178)
0.1 0.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 3.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.5 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0043621 protein self-association(GO:0043621)
0.1 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 1.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 6.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)