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ENCODE cell lines, expression (Ernst 2011)

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Results for RFX7_RFX4_RFX1

Z-value: 1.10

Motif logo

Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol Gene ID Gene Info
ENSG00000181827.10 RFX7
ENSG00000111783.8 RFX4
ENSG00000132005.4 RFX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX7hg19_v2_chr15_-_56535464_56535521-0.322.3e-01Click!
RFX1hg19_v2_chr19_-_14117074_141171410.224.2e-01Click!

Activity profile of RFX7_RFX4_RFX1 motif

Sorted Z-values of RFX7_RFX4_RFX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_15397732 4.26 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
TUSC3
tumor suppressor candidate 3
chr4_-_156298028 2.43 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chrX_+_135251783 1.94 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr4_-_156297949 1.84 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr4_-_156298087 1.81 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr14_-_102771516 1.68 ENST00000524214.1
ENST00000193029.6
ENST00000361847.2
MOK
MOK protein kinase
chr14_-_102771462 1.63 ENST00000522874.1
MOK
MOK protein kinase
chrX_+_135252050 1.60 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr19_-_45953983 1.58 ENST00000592083.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chrX_+_135251835 1.40 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr12_+_13349650 1.37 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr4_+_26585686 1.36 ENST00000505206.1
ENST00000511789.1
TBC1D19
TBC1 domain family, member 19
chr4_+_26585538 1.30 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr20_+_17550691 1.18 ENST00000474024.1
DSTN
destrin (actin depolymerizing factor)
chr2_-_190044480 1.16 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr1_+_150480551 1.14 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr11_-_62521614 1.11 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chrX_-_114252193 1.08 ENST00000243213.1
IL13RA2
interleukin 13 receptor, alpha 2
chrX_+_47444613 1.07 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr11_+_69455855 1.06 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr1_+_150480576 1.06 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr20_+_17550489 1.03 ENST00000246069.7
DSTN
destrin (actin depolymerizing factor)
chr10_-_95241951 1.02 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr10_-_95242044 0.99 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr12_-_47473707 0.96 ENST00000429635.1
AMIGO2
adhesion molecule with Ig-like domain 2
chr11_+_113185533 0.96 ENST00000393020.1
TTC12
tetratricopeptide repeat domain 12
chr1_-_85156090 0.92 ENST00000605755.1
ENST00000437941.2
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr16_-_84538218 0.92 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1
TBC/LysM-associated domain containing 1
chr9_-_130635741 0.89 ENST00000223836.10
AK1
adenylate kinase 1
chr1_-_85156216 0.88 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr11_-_108422926 0.88 ENST00000428840.1
ENST00000526312.1
EXPH5
exophilin 5
chr19_-_58609570 0.87 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
ZSCAN18
zinc finger and SCAN domain containing 18
chr11_+_113185251 0.86 ENST00000529221.1
TTC12
tetratricopeptide repeat domain 12
chr8_+_59323823 0.80 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr6_+_116601265 0.78 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr7_+_55177416 0.71 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr15_+_71184931 0.70 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr9_-_110251836 0.67 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr2_-_175869936 0.66 ENST00000409900.3
CHN1
chimerin 1
chr2_-_175870085 0.66 ENST00000409156.3
CHN1
chimerin 1
chr3_-_123339418 0.64 ENST00000583087.1
MYLK
myosin light chain kinase
chr15_+_71185148 0.63 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr3_-_123339343 0.62 ENST00000578202.1
MYLK
myosin light chain kinase
chrX_-_13835147 0.55 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr11_+_113185292 0.53 ENST00000429951.1
ENST00000442859.1
ENST00000531164.1
ENST00000529850.1
ENST00000314756.3
ENST00000525965.1
TTC12
tetratricopeptide repeat domain 12
chr11_-_119991589 0.51 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr2_+_170335924 0.51 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5
RP11-724O16.1
Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr1_+_203595903 0.50 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr5_+_110074685 0.50 ENST00000355943.3
ENST00000447245.2
SLC25A46
solute carrier family 25, member 46
chr11_+_133938820 0.49 ENST00000299106.4
ENST00000529443.2
JAM3
junctional adhesion molecule 3
chr1_+_144220127 0.48 ENST00000369373.5
NBPF8
neuroblastoma breakpoint family, member 8
chr12_-_49582978 0.48 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr11_+_133938955 0.46 ENST00000534549.1
ENST00000441717.3
JAM3
junctional adhesion molecule 3
chr14_-_67826486 0.46 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr11_-_66103867 0.46 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr1_+_203595689 0.45 ENST00000357681.5
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr20_+_48807351 0.44 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr3_+_135741576 0.44 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr11_-_66112555 0.44 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr2_+_242088963 0.44 ENST00000438799.1
ENST00000402734.1
ENST00000423280.1
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr16_+_56691606 0.44 ENST00000334350.6
MT1F
metallothionein 1F
chr5_+_271752 0.42 ENST00000505221.1
ENST00000509581.1
ENST00000507528.1
PDCD6
programmed cell death 6
chr1_-_43638168 0.42 ENST00000431635.2
EBNA1BP2
EBNA1 binding protein 2
chr1_+_206808918 0.40 ENST00000367108.3
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr19_-_39390440 0.40 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr19_+_751122 0.39 ENST00000215582.6
MISP
mitotic spindle positioning
chr1_+_206809113 0.39 ENST00000441486.1
ENST00000367106.1
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr1_+_206808868 0.38 ENST00000367109.2
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr2_+_242089046 0.37 ENST00000407025.1
ENST00000272983.8
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr14_-_24664776 0.37 ENST00000530468.1
ENST00000528010.1
ENST00000396854.4
ENST00000524835.1
ENST00000261789.4
ENST00000525592.1
TM9SF1
transmembrane 9 superfamily member 1
chr14_-_61116168 0.36 ENST00000247182.6
SIX1
SIX homeobox 1
chr5_-_180237445 0.36 ENST00000393340.3
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr18_-_33702078 0.36 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr19_-_39390350 0.35 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr8_-_98290087 0.35 ENST00000322128.3
TSPYL5
TSPY-like 5
chr8_+_10530155 0.35 ENST00000521818.1
C8orf74
chromosome 8 open reading frame 74
chr1_-_159893507 0.35 ENST00000368096.1
TAGLN2
transgelin 2
chr9_+_19049372 0.34 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr2_-_31361543 0.34 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_52285131 0.33 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr14_-_24664540 0.33 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
TM9SF1
transmembrane 9 superfamily member 1
chr3_-_107941230 0.33 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr14_-_88459503 0.33 ENST00000393568.4
ENST00000261304.2
GALC
galactosylceramidase
chr11_+_73882144 0.33 ENST00000328257.8
PPME1
protein phosphatase methylesterase 1
chr11_+_124543694 0.33 ENST00000227135.2
ENST00000532692.1
SPA17
sperm autoantigenic protein 17
chr2_+_220110177 0.33 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
STK16
serine/threonine kinase 16
chr16_+_3550924 0.33 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
CLUAP1
clusterin associated protein 1
chr17_+_17876127 0.33 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr16_+_57673430 0.32 ENST00000540164.2
ENST00000568531.1
GPR56
G protein-coupled receptor 56
chr12_-_105629852 0.32 ENST00000551662.1
ENST00000553097.1
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr11_-_10562710 0.32 ENST00000528665.1
ENST00000265981.2
RNF141
ring finger protein 141
chr11_+_73882311 0.32 ENST00000398427.4
ENST00000544401.1
PPME1
protein phosphatase methylesterase 1
chr2_-_220110111 0.32 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L
galactosidase, beta 1-like
chr19_-_46974741 0.31 ENST00000313683.10
ENST00000602246.1
PNMAL1
paraneoplastic Ma antigen family-like 1
chr9_+_26956371 0.31 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr19_-_46974664 0.31 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr15_+_49913201 0.31 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr17_-_17875688 0.31 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr1_+_211432775 0.30 ENST00000419091.2
RCOR3
REST corepressor 3
chr2_-_9143786 0.29 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr14_-_23388338 0.29 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23
RNA binding motif protein 23
chr14_+_105452094 0.29 ENST00000551606.1
ENST00000547315.1
C14orf79
chromosome 14 open reading frame 79
chr4_+_668348 0.29 ENST00000511290.1
MYL5
myosin, light chain 5, regulatory
chr7_-_137028534 0.29 ENST00000348225.2
PTN
pleiotrophin
chr15_-_85197501 0.29 ENST00000434634.2
WDR73
WD repeat domain 73
chr6_-_43484718 0.29 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr12_-_105630016 0.29 ENST00000258530.3
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr15_+_67430339 0.29 ENST00000439724.3
SMAD3
SMAD family member 3
chr6_+_52285046 0.29 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr15_+_49913175 0.29 ENST00000403028.3
DTWD1
DTW domain containing 1
chr20_-_30311703 0.28 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1
BCL2-like 1
chr18_+_54318566 0.28 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr22_+_31477296 0.28 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
SMTN
smoothelin
chr19_+_52693259 0.28 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr13_+_21141270 0.28 ENST00000319980.6
ENST00000537103.1
ENST00000389373.3
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr17_-_64187973 0.27 ENST00000583358.1
ENST00000392769.2
CEP112
centrosomal protein 112kDa
chr2_-_110371412 0.27 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
SEPT10
septin 10
chr3_-_123304017 0.27 ENST00000383657.5
PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr2_-_110371777 0.27 ENST00000397712.2
SEPT10
septin 10
chr17_-_80656528 0.27 ENST00000538809.2
ENST00000269347.6
ENST00000571995.1
RAB40B
RAB40B, member RAS oncogene family
chr1_-_6420737 0.27 ENST00000541130.1
ENST00000377845.3
ACOT7
acyl-CoA thioesterase 7
chrX_+_154114635 0.27 ENST00000369446.2
F8A1
coagulation factor VIII-associated 1
chr11_-_64546202 0.27 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1
splicing factor 1
chr11_-_118436707 0.26 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr11_-_118436606 0.26 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr2_-_220110187 0.26 ENST00000295759.7
ENST00000392089.2
GLB1L
galactosidase, beta 1-like
chr11_-_3078616 0.26 ENST00000401769.3
ENST00000278224.9
ENST00000397114.3
ENST00000380525.4
CARS
cysteinyl-tRNA synthetase
chrX_-_154688276 0.26 ENST00000369445.2
F8A3
coagulation factor VIII-associated 3
chr6_-_116601044 0.26 ENST00000368608.3
TSPYL1
TSPY-like 1
chr11_+_65779283 0.26 ENST00000312134.2
CST6
cystatin E/M
chr13_+_21141208 0.25 ENST00000351808.5
IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr18_+_54318616 0.25 ENST00000254442.3
WDR7
WD repeat domain 7
chr3_+_111718036 0.25 ENST00000455401.2
TAGLN3
transgelin 3
chr17_-_64188177 0.25 ENST00000535342.2
CEP112
centrosomal protein 112kDa
chr1_+_1447517 0.25 ENST00000378756.3
ENST00000378755.5
ATAD3A
ATPase family, AAA domain containing 3A
chr1_+_181003067 0.25 ENST00000434571.2
ENST00000367579.3
ENST00000282990.6
ENST00000367580.5
MR1
major histocompatibility complex, class I-related
chr12_+_111051902 0.25 ENST00000397655.3
ENST00000471804.2
ENST00000377654.3
ENST00000397659.4
TCTN1
tectonic family member 1
chr16_-_88923285 0.25 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr11_+_63753883 0.25 ENST00000538426.1
ENST00000543004.1
OTUB1
OTU domain, ubiquitin aldehyde binding 1
chr5_-_43313574 0.24 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr14_+_74416989 0.24 ENST00000334571.2
ENST00000554920.1
COQ6
coenzyme Q6 monooxygenase
chr12_-_125401885 0.24 ENST00000542416.1
UBC
ubiquitin C
chr2_-_110371720 0.24 ENST00000356688.4
SEPT10
septin 10
chrX_+_154611749 0.24 ENST00000369505.3
F8A2
coagulation factor VIII-associated 2
chr12_+_111051832 0.24 ENST00000550703.2
ENST00000551590.1
TCTN1
tectonic family member 1
chr7_+_155090271 0.23 ENST00000476756.1
INSIG1
insulin induced gene 1
chr6_-_167275991 0.23 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_43484621 0.23 ENST00000506469.1
ENST00000503972.1
YIPF3
Yip1 domain family, member 3
chr16_+_16429787 0.23 ENST00000331436.4
ENST00000541593.1
AC138969.4
Protein PKD1P1
chr22_+_23487513 0.23 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr2_+_84743562 0.23 ENST00000389394.3
ENST00000398278.2
DNAH6
dynein, axonemal, heavy chain 6
chr1_-_21044489 0.23 ENST00000247986.2
KIF17
kinesin family member 17
chr19_-_40324255 0.22 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr17_-_76899275 0.22 ENST00000322630.2
ENST00000586713.1
DDC8
Protein DDC8 homolog
chr7_+_158649242 0.22 ENST00000407559.3
WDR60
WD repeat domain 60
chr6_-_159065741 0.22 ENST00000367085.3
ENST00000367089.3
DYNLT1
dynein, light chain, Tctex-type 1
chr3_+_111717600 0.22 ENST00000273368.4
TAGLN3
transgelin 3
chr2_+_214149113 0.21 ENST00000331683.5
ENST00000432529.2
ENST00000413312.1
ENST00000272898.7
ENST00000447990.1
SPAG16
sperm associated antigen 16
chr15_+_42066632 0.21 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr1_-_217804377 0.21 ENST00000366935.3
ENST00000366934.3
GPATCH2
G patch domain containing 2
chr2_+_238767517 0.21 ENST00000404910.2
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr22_-_36357671 0.21 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr20_-_49575081 0.20 ENST00000371588.5
ENST00000371582.4
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr1_+_207226574 0.20 ENST00000367080.3
ENST00000367079.2
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr19_+_12848299 0.20 ENST00000357332.3
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr11_-_3078838 0.20 ENST00000397111.5
CARS
cysteinyl-tRNA synthetase
chr20_-_49575058 0.20 ENST00000371584.4
ENST00000371583.5
ENST00000413082.1
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr3_+_111717511 0.20 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr2_-_44588893 0.20 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr19_-_10679697 0.20 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr3_-_121468513 0.20 ENST00000494517.1
ENST00000393667.3
GOLGB1
golgin B1
chr5_-_143550159 0.20 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
YIPF5
Yip1 domain family, member 5
chr19_-_51523412 0.20 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr3_-_37216055 0.20 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr10_-_99161033 0.20 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr5_+_271733 0.20 ENST00000264933.4
PDCD6
programmed cell death 6
chr2_+_27851863 0.19 ENST00000264718.3
ENST00000610189.1
GPN1
GPN-loop GTPase 1
chr21_-_44846999 0.19 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr14_+_61447927 0.19 ENST00000451406.1
SLC38A6
solute carrier family 38, member 6
chr14_-_75643296 0.19 ENST00000303575.4
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr22_+_38453207 0.19 ENST00000404072.3
ENST00000424694.1
PICK1
protein interacting with PRKCA 1
chr17_-_56084578 0.18 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1
serine/arginine-rich splicing factor 1
chr16_+_15031300 0.18 ENST00000328085.6
NPIPA1
nuclear pore complex interacting protein family, member A1
chr5_-_143550241 0.18 ENST00000522203.1
YIPF5
Yip1 domain family, member 5
chr14_+_61447832 0.18 ENST00000354886.2
ENST00000267488.4
SLC38A6
solute carrier family 38, member 6
chr11_+_112832133 0.18 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr1_+_15736359 0.18 ENST00000375980.4
EFHD2
EF-hand domain family, member D2
chr2_+_239229129 0.18 ENST00000391994.2
TRAF3IP1
TNF receptor-associated factor 3 interacting protein 1
chr16_-_11363178 0.18 ENST00000312693.3
TNP2
transition protein 2 (during histone to protamine replacement)
chr5_-_54529415 0.18 ENST00000282572.4
CCNO
cyclin O
chr16_+_14805546 0.18 ENST00000552140.1
NPIPA3
nuclear pore complex interacting protein family, member A3
chr5_+_68530668 0.18 ENST00000506563.1
CDK7
cyclin-dependent kinase 7
chr11_-_507184 0.18 ENST00000533410.1
ENST00000354420.2
ENST00000397604.3
ENST00000531149.1
ENST00000356187.5
RNH1
ribonuclease/angiogenin inhibitor 1
chr5_+_49963239 0.17 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr13_+_38923959 0.17 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr13_-_30881621 0.17 ENST00000380615.3
KATNAL1
katanin p60 subunit A-like 1
chr1_-_45140227 0.17 ENST00000372237.3
TMEM53
transmembrane protein 53
chr22_+_38453378 0.17 ENST00000437453.1
ENST00000356976.3
PICK1
protein interacting with PRKCA 1
chr11_-_506739 0.16 ENST00000529306.1
ENST00000438658.2
ENST00000527485.1
ENST00000397615.2
ENST00000397614.1
RNH1
ribonuclease/angiogenin inhibitor 1
chr1_-_183604794 0.16 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.5 4.3 GO:0015693 magnesium ion transport(GO:0015693)
0.3 1.0 GO:0033241 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 2.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.3 1.2 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.2 0.7 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2 0.7 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 1.2 GO:0035617 stress granule disassembly(GO:0035617)
0.2 2.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 0.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 1.9 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.5 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.2 1.1 GO:0070141 response to UV-A(GO:0070141)
0.1 1.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 1.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.4 GO:0030910 olfactory placode formation(GO:0030910) myotome development(GO:0061055) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.2 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 1.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.6 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.3 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 5.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 2.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 1.4 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.1 GO:0030317 sperm motility(GO:0030317)
0.1 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.3 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.3 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.5 GO:0051610 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.2 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 1.0 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 1.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.2 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.8 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 2.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:0009642 response to light intensity(GO:0009642)
0.0 0.4 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.9 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) positive regulation of beta-amyloid clearance(GO:1900223)
0.0 0.5 GO:0032402 melanosome transport(GO:0032402)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.6 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 2.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.3 1.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 0.8 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.7 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 0.5 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 0.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 4.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.1 0.2 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 4.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0045503 dynein light chain binding(GO:0045503)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 5.3 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.8 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.4 4.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 0.7 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.2 1.6 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.7 GO:0033010 paranodal junction(GO:0033010)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 2.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 2.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.5 GO:0097546 ciliary base(GO:0097546)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:1990130 EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.5 GO:0034464 BBSome(GO:0034464)
0.1 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 1.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0031514 motile cilium(GO:0031514)
0.0 0.5 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)