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ENCODE cell lines, expression (Ernst 2011)

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Results for RORA

Z-value: 0.90

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Transcription factors associated with RORA

Gene Symbol Gene ID Gene Info
RORA
ENSG00000069667.11 RORA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RORAhg19_v2_chr15_-_60884706_60884743,
hg19_v2_chr15_-_61521495_61521518		-0.087.6e-01Click!

Activity profile of RORA motif

Sorted Z-values of RORA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RORA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_93964158 3.33 ENST00000549206.1
 SOCS2
 suppressor of cytokine signaling 2
chr12_+_93963590 2.95 ENST00000340600.2
 SOCS2
 suppressor of cytokine signaling 2
chr16_-_88717423 2.00 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
 CYBA
 cytochrome b-245, alpha polypeptide
chr7_+_112063192 1.36 ENST00000005558.4
 IFRD1
 interferon-related developmental regulator 1
chr1_-_85156216 1.34 ENST00000342203.3
ENST00000370612.4
 SSX2IP
 synovial sarcoma, X breakpoint 2 interacting protein
chr3_-_141747950 1.22 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr6_-_41039567 1.19 ENST00000468811.1
 OARD1
 O-acyl-ADP-ribose deacylase 1
chr9_-_130966497 1.17 ENST00000393608.1
ENST00000372948.3
 CIZ1
 CDKN1A interacting zinc finger protein 1
chrX_-_71526999 1.10 ENST00000453707.2
ENST00000373619.3
 CITED1
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr7_-_45151272 1.07 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
 TBRG4
 transforming growth factor beta regulator 4
chr7_-_123197733 1.00 ENST00000470123.1
ENST00000471770.1
 NDUFA5
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr10_+_81107271 0.98 ENST00000448165.1
 PPIF
 peptidylprolyl isomerase F
chr9_+_134103496 0.87 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
 NUP214
 nucleoporin 214kDa
chr1_-_150207017 0.81 ENST00000369119.3
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_48785216 0.76 ENST00000285243.6
 ANKRD40
 ankyrin repeat domain 40
chr11_-_64511575 0.72 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_55669093 0.71 ENST00000344887.5
 TNNI3
 troponin I type 3 (cardiac)
chr1_+_206858328 0.68 ENST00000367103.3
 MAPKAPK2
 mitogen-activated protein kinase-activated protein kinase 2
chr1_+_229440129 0.65 ENST00000366688.3
 SPHAR
 S-phase response (cyclin related)
chr21_-_43816152 0.58 ENST00000433957.2
ENST00000398397.3
 TMPRSS3
 transmembrane protease, serine 3
chr1_-_32403903 0.57 ENST00000344035.6
ENST00000356536.3
 PTP4A2
 protein tyrosine phosphatase type IVA, member 2
chrX_-_43741594 0.56 ENST00000536181.1
ENST00000378069.4
 MAOB
 monoamine oxidase B
chr1_+_212738676 0.55 ENST00000366981.4
ENST00000366987.2
 ATF3
 activating transcription factor 3
chr21_-_43816052 0.55 ENST00000398405.1
 TMPRSS3
 transmembrane protease, serine 3
chrX_-_129299638 0.55 ENST00000535724.1
ENST00000346424.2
 AIFM1
 apoptosis-inducing factor, mitochondrion-associated, 1
chr18_-_19284724 0.50 ENST00000580981.1
ENST00000289119.2
 ABHD3
 abhydrolase domain containing 3
chr1_-_33502441 0.50 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
 AK2
 adenylate kinase 2
chr11_-_64512273 0.48 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_41132010 0.48 ENST00000409103.1
ENST00000360221.4
 PTGES3L-AARSD1
 PTGES3L-AARSD1 readthrough
chr19_-_39826639 0.48 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
 GMFG
 glia maturation factor, gamma
chr19_-_50311896 0.44 ENST00000529634.2
 FUZ
 fuzzy planar cell polarity protein
chr1_+_206858232 0.44 ENST00000294981.4
 MAPKAPK2
 mitogen-activated protein kinase-activated protein kinase 2
chr11_-_104480019 0.43 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
 RP11-886D15.1
 RP11-886D15.1
chr6_-_41703296 0.43 ENST00000373033.1
 TFEB
 transcription factor EB
chr11_+_64879317 0.42 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
 TM7SF2
 transmembrane 7 superfamily member 2
chr1_-_33502528 0.42 ENST00000354858.6
 AK2
 adenylate kinase 2
chr18_-_12377283 0.42 ENST00000269143.3
 AFG3L2
 AFG3-like AAA ATPase 2
chr11_+_111957497 0.42 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
 SDHD
 succinate dehydrogenase complex, subunit D, integral membrane protein
chr16_-_30457048 0.42 ENST00000500504.2
ENST00000542752.1
 SEPHS2
 selenophosphate synthetase 2
chr1_-_241799232 0.42 ENST00000366553.1
 CHML
 choroideremia-like (Rab escort protein 2)
chr14_-_102552659 0.41 ENST00000441629.2
 HSP90AA1
 heat shock protein 90kDa alpha (cytosolic), class A member 1
chr7_-_140179276 0.40 ENST00000443720.2
ENST00000255977.2
 MKRN1
 makorin ring finger protein 1
chr3_-_24536253 0.40 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
 THRB
 thyroid hormone receptor, beta
chr19_+_46850251 0.40 ENST00000012443.4
 PPP5C
 protein phosphatase 5, catalytic subunit
chr12_+_120875910 0.39 ENST00000551806.1
 AL021546.6
 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr12_-_53320245 0.39 ENST00000552150.1
 KRT8
 keratin 8
chr16_-_30538079 0.38 ENST00000562803.1
 ZNF768
 zinc finger protein 768
chr10_-_52645379 0.37 ENST00000395489.2
 A1CF
 APOBEC1 complementation factor
chr19_+_46850320 0.36 ENST00000391919.1
 PPP5C
 protein phosphatase 5, catalytic subunit
chr17_+_49230897 0.36 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
 NME1
NME1-NME2
NME2
 NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr11_+_66624527 0.35 ENST00000393952.3
 LRFN4
 leucine rich repeat and fibronectin type III domain containing 4
chr16_-_30537839 0.35 ENST00000380412.5
 ZNF768
 zinc finger protein 768
chr7_-_127983877 0.35 ENST00000415472.2
ENST00000478061.1
ENST00000223073.2
ENST00000459726.1
 RBM28
 RNA binding motif protein 28
chr10_-_52645416 0.34 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
 A1CF
 APOBEC1 complementation factor
chr6_-_89673280 0.34 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
 RNGTT
 RNA guanylyltransferase and 5'-phosphatase
chr7_-_25164969 0.34 ENST00000305786.2
 CYCS
 cytochrome c, somatic
chr1_+_32666188 0.33 ENST00000421922.2
 CCDC28B
 coiled-coil domain containing 28B
chr3_+_113465866 0.32 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
 ATP6V1A
 ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr6_-_97345689 0.31 ENST00000316149.7
 NDUFAF4
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr10_-_104178857 0.30 ENST00000020673.5
 PSD
 pleckstrin and Sec7 domain containing
chr6_+_107077435 0.30 ENST00000369046.4
 QRSL1
 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr19_+_16059818 0.30 ENST00000322107.1
 OR10H4
 olfactory receptor, family 10, subfamily H, member 4
chr17_-_42144949 0.30 ENST00000591247.1
 LSM12
 LSM12 homolog (S. cerevisiae)
chr16_+_21964662 0.29 ENST00000561553.1
ENST00000565331.1
 UQCRC2
 ubiquinol-cytochrome c reductase core protein II
chr6_+_167525277 0.28 ENST00000400926.2
 CCR6
 chemokine (C-C motif) receptor 6
chr21_-_46330545 0.28 ENST00000320216.6
ENST00000397852.1
 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr9_+_139717847 0.27 ENST00000436380.1
 RABL6
 RAB, member RAS oncogene family-like 6
chr3_-_183735731 0.27 ENST00000334444.6
 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr15_+_78441663 0.27 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
 IDH3A
 isocitrate dehydrogenase 3 (NAD+) alpha
chr7_+_73868439 0.26 ENST00000424337.2
 GTF2IRD1
 GTF2I repeat domain containing 1
chr9_-_35103105 0.25 ENST00000452248.2
ENST00000356493.5
 STOML2
 stomatin (EPB72)-like 2
chr15_+_43809797 0.25 ENST00000399453.1
ENST00000300231.5
 MAP1A
 microtubule-associated protein 1A
chr5_-_140027357 0.25 ENST00000252102.4
 NDUFA2
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr5_-_140027175 0.24 ENST00000512088.1
 NDUFA2
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr11_-_67271723 0.23 ENST00000533391.1
ENST00000534749.1
ENST00000532703.1
 PITPNM1
 phosphatidylinositol transfer protein, membrane-associated 1
chr16_-_1821496 0.22 ENST00000564628.1
ENST00000563498.1
 NME3
 NME/NM23 nucleoside diphosphate kinase 3
chr5_+_169780485 0.22 ENST00000377360.4
 KCNIP1
 Kv channel interacting protein 1
chr2_+_198365095 0.22 ENST00000409468.1
 HSPE1
 heat shock 10kDa protein 1
chr10_-_94003003 0.22 ENST00000412050.4
 CPEB3
 cytoplasmic polyadenylation element binding protein 3
chr19_-_11689752 0.21 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
 ACP5
 acid phosphatase 5, tartrate resistant
chr1_-_85040090 0.20 ENST00000370630.5
 CTBS
 chitobiase, di-N-acetyl-
chr14_-_101295407 0.20 ENST00000596284.1
 AL117190.2
 AL117190.2
chr3_+_45067659 0.20 ENST00000296130.4
 CLEC3B
 C-type lectin domain family 3, member B
chr11_+_118272328 0.19 ENST00000524422.1
 ATP5L
 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr11_-_111741994 0.19 ENST00000398006.2
 ALG9
 ALG9, alpha-1,2-mannosyltransferase
chr3_-_113465065 0.19 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
 NAA50
 N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr17_+_40996590 0.18 ENST00000253799.3
ENST00000452774.2
 AOC2
 amine oxidase, copper containing 2 (retina-specific)
chr11_-_132813566 0.17 ENST00000331898.7
 OPCML
 opioid binding protein/cell adhesion molecule-like
chr18_+_32073253 0.16 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA
 dystrobrevin, alpha
chr7_-_150777874 0.16 ENST00000540185.1
 FASTK
 Fas-activated serine/threonine kinase
chr19_-_39926268 0.15 ENST00000599705.1
 RPS16
 ribosomal protein S16
chr10_+_104178946 0.15 ENST00000432590.1
 FBXL15
 F-box and leucine-rich repeat protein 15
chr16_+_72088376 0.14 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
 HP
HPR
 haptoglobin
haptoglobin-related protein
chr20_-_3748416 0.14 ENST00000399672.1
 C20orf27
 chromosome 20 open reading frame 27
chr14_-_58893832 0.14 ENST00000556007.2
 TIMM9
 translocase of inner mitochondrial membrane 9 homolog (yeast)
chr19_-_49140609 0.13 ENST00000601104.1
 DBP
 D site of albumin promoter (albumin D-box) binding protein
chr1_+_29213678 0.13 ENST00000347529.3
 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr11_-_790060 0.12 ENST00000330106.4
 CEND1
 cell cycle exit and neuronal differentiation 1
chr16_+_31366536 0.12 ENST00000562522.1
 ITGAX
 integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_-_205719295 0.12 ENST00000367142.4
 NUCKS1
 nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_-_131347501 0.12 ENST00000543479.1
 ACSL6
 acyl-CoA synthetase long-chain family member 6
chr11_-_64511789 0.11 ENST00000419843.1
ENST00000394430.1
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_+_48046538 0.10 ENST00000240306.3
 DLX4
 distal-less homeobox 4
chr3_-_49158312 0.10 ENST00000398892.3
ENST00000453664.1
ENST00000398888.2
 USP19
 ubiquitin specific peptidase 19
chr17_-_49198216 0.10 ENST00000262013.7
ENST00000357122.4
 SPAG9
 sperm associated antigen 9
chr20_+_49126881 0.10 ENST00000371621.3
ENST00000541713.1
 PTPN1
 protein tyrosine phosphatase, non-receptor type 1
chrX_+_18725758 0.10 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
 PPEF1
 protein phosphatase, EF-hand calcium binding domain 1
chr12_+_56414851 0.09 ENST00000547167.1
 IKZF4
 IKAROS family zinc finger 4 (Eos)
chr5_-_131347583 0.07 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
 ACSL6
 acyl-CoA synthetase long-chain family member 6
chr3_-_42845951 0.07 ENST00000418900.2
ENST00000430190.1
 HIGD1A
 HIG1 hypoxia inducible domain family, member 1A
chrX_+_153770421 0.07 ENST00000369609.5
ENST00000369607.1
 IKBKG
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr10_-_65028938 0.07 ENST00000402544.1
 JMJD1C
 jumonji domain containing 1C
chrX_-_108725301 0.07 ENST00000218006.2
 GUCY2F
 guanylate cyclase 2F, retinal
chr2_+_162016827 0.07 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
 TANK
 TRAF family member-associated NFKB activator
chr19_-_42931567 0.07 ENST00000244289.4
 LIPE
 lipase, hormone-sensitive
chr11_-_119599794 0.07 ENST00000264025.3
 PVRL1
 poliovirus receptor-related 1 (herpesvirus entry mediator C)
chrX_+_16737718 0.06 ENST00000380155.3
 SYAP1
 synapse associated protein 1
chr5_+_32788945 0.06 ENST00000326958.1
 AC026703.1
 AC026703.1
chr16_+_82090028 0.05 ENST00000568090.1
 HSD17B2
 hydroxysteroid (17-beta) dehydrogenase 2
chr2_-_86422095 0.05 ENST00000254636.5
 IMMT
 inner membrane protein, mitochondrial
chr16_+_2076869 0.05 ENST00000424542.2
ENST00000432365.2
 SLC9A3R2
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr13_+_22245522 0.04 ENST00000382353.5
 FGF9
 fibroblast growth factor 9
chr20_+_37590942 0.04 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
 DHX35
 DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr12_-_16761007 0.04 ENST00000354662.1
ENST00000441439.2
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr1_-_154164534 0.04 ENST00000271850.7
ENST00000368530.2
 TPM3
 tropomyosin 3
chr1_+_9294822 0.03 ENST00000377403.2
 H6PD
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr1_-_157108266 0.03 ENST00000326786.4
 ETV3
 ets variant 3
chr6_-_43021437 0.03 ENST00000265348.3
 CUL7
 cullin 7
chr10_-_14050522 0.03 ENST00000342409.2
 FRMD4A
 FERM domain containing 4A
chr1_-_157108130 0.02 ENST00000368192.4
 ETV3
 ets variant 3
chr17_-_27503770 0.01 ENST00000533112.1
 MYO18A
 myosin XVIIIA
chr8_-_100905850 0.01 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
 COX6C
 cytochrome c oxidase subunit VIc
chr22_-_32341336 0.01 ENST00000248984.3
 C22orf24
 chromosome 22 open reading frame 24
chr12_-_57039739 0.01 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
 ATP5B
 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.4 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.3 GO:0004040 amidase activity(GO:0004040)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 2.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0030172 troponin C binding(GO:0030172)
0.1 1.1 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.4 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.2 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.2 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 2.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 0.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 2.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.8 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 2.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) apicolateral plasma membrane(GO:0016327) glycoprotein complex(GO:0090665)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0007518 myoblast fate determination(GO:0007518)
0.4 2.0 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3 6.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 1.0 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.3 0.9 GO:0006172 ADP biosynthetic process(GO:0006172)
0.2 1.1 GO:0071105 response to interleukin-11(GO:0071105)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.5 GO:1904044 response to aldosterone(GO:1904044)
0.1 1.1 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.4 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0090301 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 1.0 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 1.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.6 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.6 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.4 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 1.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.8 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions