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ENCODE cell lines, expression (Ernst 2011)

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Results for RUNX3_BCL11A

Z-value: 1.08

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Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
RUNX3
ENSG00000020633.14 RUNX3
BCL11A
ENSG00000119866.16 BCL11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL11Ahg19_v2_chr2_-_60780702_607807420.591.5e-02Click!
RUNX3hg19_v2_chr1_-_25256368_252564760.439.9e-02Click!

Activity profile of RUNX3_BCL11A motif

Sorted Z-values of RUNX3_BCL11A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_158300556 2.27 ENST00000264192.3
 CYTIP
 cytohesin 1 interacting protein
chr22_+_40297079 1.96 ENST00000344138.4
ENST00000543252.1
 GRAP2
 GRB2-related adaptor protein 2
chr17_-_34417479 1.83 ENST00000225245.5
 CCL3
 chemokine (C-C motif) ligand 3
chr1_-_114414316 1.67 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
 PTPN22
 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr1_-_25291475 1.65 ENST00000338888.3
ENST00000399916.1
 RUNX3
 runt-related transcription factor 3
chr12_-_53012343 1.64 ENST00000305748.3
 KRT73
 keratin 73
chr22_+_40297105 1.63 ENST00000540310.1
 GRAP2
 GRB2-related adaptor protein 2
chr12_-_15114492 1.58 ENST00000541546.1
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr11_-_58345569 1.44 ENST00000528954.1
ENST00000528489.1
 LPXN
 leupaxin
chr13_-_46756351 1.37 ENST00000323076.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_36233332 1.26 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
 IGFLR1
 IGF-like family receptor 1
chr3_-_189840223 1.25 ENST00000427335.2
 LEPREL1
 leprecan-like 1
chr12_-_53594227 1.19 ENST00000550743.2
 ITGB7
 integrin, beta 7
chr8_-_102803163 1.19 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
 NCALD
 neurocalcin delta
chr6_+_45296048 1.13 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
 RUNX2
 runt-related transcription factor 2
chr15_-_37393406 1.12 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
 MEIS2
 Meis homeobox 2
chr7_+_18535346 1.08 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
 HDAC9
 histone deacetylase 9
chr15_-_55563072 1.04 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
 RAB27A
 RAB27A, member RAS oncogene family
chr7_+_116660246 0.98 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
 ST7
 suppression of tumorigenicity 7
chr17_-_39674668 0.97 ENST00000393981.3
 KRT15
 keratin 15
chr6_+_45296391 0.92 ENST00000371436.6
ENST00000576263.1
 RUNX2
 runt-related transcription factor 2
chr14_+_75988851 0.92 ENST00000555504.1
 BATF
 basic leucine zipper transcription factor, ATF-like
chr5_-_94417339 0.91 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
 MCTP1
 multiple C2 domains, transmembrane 1
chr5_+_131409476 0.87 ENST00000296871.2
 CSF2
 colony stimulating factor 2 (granulocyte-macrophage)
chr15_-_55562479 0.87 ENST00000564609.1
 RAB27A
 RAB27A, member RAS oncogene family
chr1_+_209929377 0.85 ENST00000400959.3
ENST00000367025.3
 TRAF3IP3
 TRAF3 interacting protein 3
chrX_+_37639264 0.84 ENST00000378588.4
 CYBB
 cytochrome b-245, beta polypeptide
chr10_+_17272608 0.83 ENST00000421459.2
 VIM
 vimentin
chrX_+_48542168 0.80 ENST00000376701.4
 WAS
 Wiskott-Aldrich syndrome
chr11_+_121447469 0.79 ENST00000532694.1
ENST00000534286.1
 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
chr1_+_198608146 0.77 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
 PTPRC
 protein tyrosine phosphatase, receptor type, C
chr3_+_113251143 0.76 ENST00000264852.4
ENST00000393830.3
 SIDT1
 SID1 transmembrane family, member 1
chr11_+_35198118 0.70 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
 CD44
 CD44 molecule (Indian blood group)
chr12_+_25205568 0.70 ENST00000548766.1
ENST00000556887.1
 LRMP
 lymphoid-restricted membrane protein
chr15_-_37392703 0.69 ENST00000382766.2
ENST00000444725.1
 MEIS2
 Meis homeobox 2
chr12_-_54694807 0.68 ENST00000435572.2
 NFE2
 nuclear factor, erythroid 2
chr10_+_17270214 0.68 ENST00000544301.1
 VIM
 vimentin
chrX_+_37639302 0.66 ENST00000545017.1
ENST00000536160.1
 CYBB
 cytochrome b-245, beta polypeptide
chr3_+_98250743 0.66 ENST00000284311.3
 GPR15
 G protein-coupled receptor 15
chr3_-_33686743 0.66 ENST00000333778.6
ENST00000539981.1
 CLASP2
 cytoplasmic linker associated protein 2
chr12_+_25205446 0.65 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
 LRMP
 lymphoid-restricted membrane protein
chrX_-_70838306 0.65 ENST00000373691.4
ENST00000373693.3
 CXCR3
 chemokine (C-X-C motif) receptor 3
chr6_+_116692102 0.64 ENST00000359564.2
 DSE
 dermatan sulfate epimerase
chr19_-_44285401 0.64 ENST00000262888.3
 KCNN4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr13_-_99910673 0.64 ENST00000397473.2
ENST00000397470.2
 GPR18
 G protein-coupled receptor 18
chr1_-_207095324 0.64 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
 FAIM3
 Fas apoptotic inhibitory molecule 3
chr4_-_71532339 0.64 ENST00000254801.4
 IGJ
 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr10_+_5566916 0.63 ENST00000315238.1
 CALML3
 calmodulin-like 3
chr15_-_55562582 0.62 ENST00000396307.2
 RAB27A
 RAB27A, member RAS oncogene family
chr3_+_189507432 0.60 ENST00000354600.5
 TP63
 tumor protein p63
chr1_+_209929494 0.59 ENST00000367026.3
 TRAF3IP3
 TRAF3 interacting protein 3
chr19_+_10197463 0.59 ENST00000590378.1
ENST00000397881.3
 C19orf66
 chromosome 19 open reading frame 66
chr17_-_34524157 0.59 ENST00000378354.4
ENST00000394484.1
 CCL3L3
 chemokine (C-C motif) ligand 3-like 3
chr11_+_35198243 0.59 ENST00000528455.1
 CD44
 CD44 molecule (Indian blood group)
chr1_-_206945830 0.58 ENST00000423557.1
 IL10
 interleukin 10
chr12_-_54694758 0.57 ENST00000553070.1
 NFE2
 nuclear factor, erythroid 2
chr22_+_21996549 0.56 ENST00000248958.4
 SDF2L1
 stromal cell-derived factor 2-like 1
chr16_+_85942594 0.56 ENST00000566369.1
 IRF8
 interferon regulatory factor 8
chr17_+_7239821 0.55 ENST00000158762.3
ENST00000570457.2
 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr21_-_40033618 0.55 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
chr17_-_34625719 0.54 ENST00000422211.2
ENST00000542124.1
 CCL3L1
 chemokine (C-C motif) ligand 3-like 1
chr14_+_64680854 0.54 ENST00000458046.2
 SYNE2
 spectrin repeat containing, nuclear envelope 2
chr1_+_12524965 0.53 ENST00000471923.1
 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr14_+_97263641 0.52 ENST00000216639.3
 VRK1
 vaccinia related kinase 1
chr12_+_93772402 0.52 ENST00000546925.1
 NUDT4
 nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr1_-_207095212 0.51 ENST00000420007.2
 FAIM3
 Fas apoptotic inhibitory molecule 3
chr1_+_32716840 0.49 ENST00000336890.5
 LCK
 lymphocyte-specific protein tyrosine kinase
chr1_+_111772314 0.48 ENST00000466741.1
ENST00000477185.2
 CHI3L2
 chitinase 3-like 2
chr9_+_2015335 0.46 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_-_62457371 0.46 ENST00000317449.4
 LRRN4CL
 LRRN4 C-terminal like
chr17_-_29648761 0.46 ENST00000247270.3
ENST00000462804.2
 EVI2A
 ecotropic viral integration site 2A
chrX_-_49121165 0.45 ENST00000376207.4
ENST00000376199.2
 FOXP3
 forkhead box P3
chr1_+_113161778 0.45 ENST00000263168.3
 CAPZA1
 capping protein (actin filament) muscle Z-line, alpha 1
chr9_-_34048873 0.43 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
 UBAP2
 ubiquitin associated protein 2
chr1_+_32716857 0.43 ENST00000482949.1
ENST00000495610.2
 LCK
 lymphocyte-specific protein tyrosine kinase
chr5_+_133451254 0.43 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
chr1_-_175161890 0.43 ENST00000545251.2
ENST00000423313.1
 KIAA0040
 KIAA0040
chr3_+_189349162 0.43 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
 TP63
 tumor protein p63
chr1_-_217250231 0.42 ENST00000493748.1
ENST00000463665.1
 ESRRG
 estrogen-related receptor gamma
chr19_+_36203830 0.42 ENST00000262630.3
 ZBTB32
 zinc finger and BTB domain containing 32
chr6_+_31543334 0.41 ENST00000449264.2
 TNF
 tumor necrosis factor
chr9_-_138853156 0.41 ENST00000371756.3
 UBAC1
 UBA domain containing 1
chr17_-_56082455 0.40 ENST00000578794.1
 RP11-159D12.5
 Uncharacterized protein
chr1_+_111772435 0.40 ENST00000524472.1
 CHI3L2
 chitinase 3-like 2
chr12_-_51717875 0.39 ENST00000604560.1
 BIN2
 bridging integrator 2
chr7_-_91764108 0.39 ENST00000450723.1
 CYP51A1
 cytochrome P450, family 51, subfamily A, polypeptide 1
chr2_-_172750733 0.39 ENST00000392592.4
ENST00000422440.2
 SLC25A12
 solute carrier family 25 (aspartate/glutamate carrier), member 12
chr2_+_234580525 0.37 ENST00000609637.1
 UGT1A1
 UDP glucuronosyltransferase 1 family, polypeptide A8
chr11_-_128457446 0.37 ENST00000392668.4
 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr12_-_4754339 0.37 ENST00000228850.1
 AKAP3
 A kinase (PRKA) anchor protein 3
chr2_+_74757050 0.36 ENST00000352222.3
ENST00000437202.1
 HTRA2
 HtrA serine peptidase 2
chr2_+_90077680 0.36 ENST00000390270.2
 IGKV3D-20
 immunoglobulin kappa variable 3D-20
chr1_+_152486950 0.36 ENST00000368790.3
 CRCT1
 cysteine-rich C-terminal 1
chr16_+_84801852 0.35 ENST00000569925.1
ENST00000567526.1
 USP10
 ubiquitin specific peptidase 10
chr1_+_179050512 0.35 ENST00000367627.3
 TOR3A
 torsin family 3, member A
chr19_+_49496705 0.35 ENST00000595090.1
 RUVBL2
 RuvB-like AAA ATPase 2
chr12_-_51717948 0.35 ENST00000267012.4
 BIN2
 bridging integrator 2
chr19_+_41882598 0.35 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
 TMEM91
CTC-435M10.3
 transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr12_-_51717922 0.34 ENST00000452142.2
 BIN2
 bridging integrator 2
chr14_+_75988768 0.33 ENST00000286639.6
 BATF
 basic leucine zipper transcription factor, ATF-like
chr17_-_7164410 0.33 ENST00000574070.1
 CLDN7
 claudin 7
chr6_+_63921351 0.32 ENST00000370659.1
 FKBP1C
 FK506 binding protein 1C
chr2_-_214016314 0.32 ENST00000434687.1
ENST00000374319.4
 IKZF2
 IKAROS family zinc finger 2 (Helios)
chr2_+_234545148 0.32 ENST00000373445.1
 UGT1A10
 UDP glucuronosyltransferase 1 family, polypeptide A10
chr4_+_89299885 0.32 ENST00000380265.5
ENST00000273960.3
 HERC6
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_+_89299994 0.31 ENST00000264346.7
 HERC6
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr2_-_175462456 0.31 ENST00000409891.1
ENST00000410117.1
 WIPF1
 WAS/WASL interacting protein family, member 1
chr6_+_143772060 0.31 ENST00000367591.4
 PEX3
 peroxisomal biogenesis factor 3
chr14_-_21493649 0.31 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
 NDRG2
 NDRG family member 2
chr8_+_31497271 0.30 ENST00000520407.1
 NRG1
 neuregulin 1
chr2_-_175462934 0.29 ENST00000392546.2
ENST00000436221.1
 WIPF1
 WAS/WASL interacting protein family, member 1
chr6_+_63921399 0.29 ENST00000356170.3
 FKBP1C
 FK506 binding protein 1C
chr8_-_28747424 0.29 ENST00000523436.1
ENST00000397363.4
ENST00000521777.1
ENST00000520184.1
ENST00000521022.1
 INTS9
 integrator complex subunit 9
chr4_-_57524061 0.28 ENST00000508121.1
 HOPX
 HOP homeobox
chr11_-_45940343 0.28 ENST00000532681.1
 PEX16
 peroxisomal biogenesis factor 16
chr6_+_151042224 0.28 ENST00000358517.2
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_+_33359687 0.28 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr20_+_44637526 0.27 ENST00000372330.3
 MMP9
 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr6_+_27925019 0.27 ENST00000244623.1
 OR2B6
 olfactory receptor, family 2, subfamily B, member 6
chr18_-_53089723 0.27 ENST00000561992.1
ENST00000562512.2
 TCF4
 transcription factor 4
chr8_-_28747717 0.27 ENST00000416984.2
 INTS9
 integrator complex subunit 9
chr6_-_29013017 0.27 ENST00000377175.1
 OR2W1
 olfactory receptor, family 2, subfamily W, member 1
chr12_+_93772326 0.26 ENST00000550056.1
ENST00000549992.1
ENST00000548662.1
ENST00000547014.1
 NUDT4
 nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr11_+_118958689 0.26 ENST00000535253.1
ENST00000392841.1
 HMBS
 hydroxymethylbilane synthase
chr4_-_84035868 0.26 ENST00000426923.2
ENST00000509973.1
 PLAC8
 placenta-specific 8
chr7_+_96634850 0.25 ENST00000518156.2
 DLX6
 distal-less homeobox 6
chr3_+_142342228 0.25 ENST00000337777.3
 PLS1
 plastin 1
chr21_-_31588338 0.25 ENST00000286809.1
 CLDN8
 claudin 8
chr2_+_33359646 0.24 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr9_-_35103105 0.24 ENST00000452248.2
ENST00000356493.5
 STOML2
 stomatin (EPB72)-like 2
chr1_+_45205478 0.24 ENST00000452259.1
ENST00000372224.4
 KIF2C
 kinesin family member 2C
chr19_+_13135386 0.24 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_15125954 0.24 ENST00000266395.2
 PDE6H
 phosphodiesterase 6H, cGMP-specific, cone, gamma
chr7_-_148580563 0.23 ENST00000476773.1
 EZH2
 enhancer of zeste homolog 2 (Drosophila)
chr22_+_19419425 0.23 ENST00000333130.3
 MRPL40
 mitochondrial ribosomal protein L40
chr17_+_7462103 0.23 ENST00000396545.4
 TNFSF13
 tumor necrosis factor (ligand) superfamily, member 13
chrX_-_77225135 0.23 ENST00000458128.1
 PGAM4
 phosphoglycerate mutase family member 4
chr17_-_1532106 0.22 ENST00000301335.5
ENST00000382147.4
 SLC43A2
 solute carrier family 43 (amino acid system L transporter), member 2
chr2_+_37571717 0.22 ENST00000338415.3
ENST00000404976.1
 QPCT
 glutaminyl-peptide cyclotransferase
chr12_-_102591604 0.22 ENST00000329406.4
 PMCH
 pro-melanin-concentrating hormone
chr15_-_64665911 0.22 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
 CTD-2116N17.1
 Uncharacterized protein
chr1_+_155290677 0.22 ENST00000368354.3
ENST00000368352.5
 RUSC1
 RUN and SH3 domain containing 1
chr6_+_42584847 0.22 ENST00000372883.3
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr1_+_45205498 0.22 ENST00000372218.4
 KIF2C
 kinesin family member 2C
chr1_+_50569575 0.22 ENST00000371827.1
 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
chr21_-_31588365 0.22 ENST00000399899.1
 CLDN8
 claudin 8
chr10_-_14372870 0.21 ENST00000357447.2
 FRMD4A
 FERM domain containing 4A
chr3_-_49941042 0.21 ENST00000344206.4
ENST00000296474.3
 MST1R
 macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr5_+_75699149 0.21 ENST00000379730.3
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr13_-_103053946 0.21 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr19_-_51220176 0.21 ENST00000359082.3
ENST00000293441.1
 SHANK1
 SH3 and multiple ankyrin repeat domains 1
chr1_-_113161730 0.21 ENST00000544629.1
ENST00000543570.1
ENST00000360743.4
ENST00000490067.1
ENST00000343210.7
ENST00000369666.1
 ST7L
 suppression of tumorigenicity 7 like
chr6_+_25279651 0.21 ENST00000329474.6
 LRRC16A
 leucine rich repeat containing 16A
chr2_+_37571845 0.21 ENST00000537448.1
 QPCT
 glutaminyl-peptide cyclotransferase
chr2_+_217277466 0.21 ENST00000358207.5
ENST00000434435.1
 SMARCAL1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr8_+_27183033 0.21 ENST00000420218.2
 PTK2B
 protein tyrosine kinase 2 beta
chr8_-_60031762 0.21 ENST00000361421.1
 TOX
 thymocyte selection-associated high mobility group box
chr2_+_217277137 0.20 ENST00000430374.1
ENST00000357276.4
ENST00000444508.1
 SMARCAL1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr12_-_24103954 0.20 ENST00000441133.2
ENST00000545921.1
 SOX5
 SRY (sex determining region Y)-box 5
chr6_-_46048116 0.20 ENST00000185206.6
 CLIC5
 chloride intracellular channel 5
chrX_-_118739835 0.20 ENST00000542113.1
ENST00000304449.5
 NKRF
 NFKB repressing factor
chr1_-_179112173 0.20 ENST00000408940.3
ENST00000504405.1
 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
chr19_-_17375541 0.20 ENST00000252597.3
 USHBP1
 Usher syndrome 1C binding protein 1
chr2_+_44001172 0.20 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
 DYNC2LI1
 dynein, cytoplasmic 2, light intermediate chain 1
chr5_-_137071756 0.20 ENST00000394937.3
ENST00000309755.4
 KLHL3
 kelch-like family member 3
chr15_+_68582544 0.20 ENST00000566008.1
 FEM1B
 fem-1 homolog b (C. elegans)
chr18_+_13611431 0.20 ENST00000587757.1
 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
chr9_-_117853297 0.19 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
 TNC
 tenascin C
chr16_+_29674540 0.19 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
 SPN
QPRT
 sialophorin
quinolinate phosphoribosyltransferase
chr2_+_73461410 0.19 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
 CCT7
 chaperonin containing TCP1, subunit 7 (eta)
chr6_+_131571535 0.19 ENST00000474850.2
 AKAP7
 A kinase (PRKA) anchor protein 7
chr8_+_27182862 0.19 ENST00000521164.1
ENST00000346049.5
 PTK2B
 protein tyrosine kinase 2 beta
chr6_+_111195973 0.19 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
 AMD1
 adenosylmethionine decarboxylase 1
chr17_+_45810594 0.18 ENST00000177694.1
 TBX21
 T-box 21
chr12_-_27090896 0.18 ENST00000539625.1
ENST00000538727.1
 ASUN
 asunder spermatogenesis regulator
chr8_+_27168988 0.18 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
 PTK2B
 protein tyrosine kinase 2 beta
chr7_-_140482926 0.18 ENST00000496384.2
 BRAF
 v-raf murine sarcoma viral oncogene homolog B
chrX_-_49041242 0.18 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
 PRICKLE3
 prickle homolog 3 (Drosophila)
chr20_-_25062767 0.18 ENST00000429762.3
ENST00000444511.2
ENST00000376707.3
 VSX1
 visual system homeobox 1
chr1_+_63788730 0.18 ENST00000371116.2
 FOXD3
 forkhead box D3
chr2_+_79412357 0.17 ENST00000466387.1
 CTNNA2
 catenin (cadherin-associated protein), alpha 2
chr17_-_19281203 0.17 ENST00000487415.2
 B9D1
 B9 protein domain 1
chr1_-_223536679 0.17 ENST00000608996.1
 SUSD4
 sushi domain containing 4
chr12_-_109025849 0.17 ENST00000228463.6
 SELPLG
 selectin P ligand
chrX_+_68048803 0.17 ENST00000204961.4
 EFNB1
 ephrin-B1
chr11_-_67141090 0.17 ENST00000312438.7
 CLCF1
 cardiotrophin-like cytokine factor 1
chr4_-_109087872 0.17 ENST00000510624.1
 LEF1
 lymphoid enhancer-binding factor 1
chr1_-_150979333 0.17 ENST00000312210.5
 FAM63A
 family with sequence similarity 63, member A
chr5_+_75699040 0.17 ENST00000274364.6
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr7_-_115670804 0.17 ENST00000320239.7
 TFEC
 transcription factor EC
chr3_+_51575596 0.16 ENST00000409535.2
 RAD54L2
 RAD54-like 2 (S. cerevisiae)
chr7_-_115670792 0.16 ENST00000265440.7
ENST00000393485.1
 TFEC
 transcription factor EC
chr2_+_73461364 0.16 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
 CCT7
 chaperonin containing TCP1, subunit 7 (eta)
chr3_-_10547192 0.16 ENST00000360273.2
ENST00000343816.4
 ATP2B2
 ATPase, Ca++ transporting, plasma membrane 2
chr16_+_2570340 0.16 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
 AMDHD2
 amidohydrolase domain containing 2
chr12_-_68553512 0.16 ENST00000229135.3
 IFNG
 interferon, gamma
chr1_+_149553003 0.16 ENST00000369222.3
 PPIAL4C
 peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr5_-_39203093 0.16 ENST00000515010.1
 FYB
 FYN binding protein
chr20_+_54987305 0.16 ENST00000371336.3
ENST00000434344.1
 CASS4
 Cas scaffolding protein family member 4
chr3_+_111260954 0.16 ENST00000283285.5
 CD96
 CD96 molecule

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 1.5 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 0.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.8 GO:0052848 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 0.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.5 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 2.5 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.2 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.8 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 2.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0004878 complement component C5a receptor activity(GO:0004878)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 5.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.5 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.4 2.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.4 1.6 GO:0071461 cellular response to redox state(GO:0071461)
0.3 1.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.3 1.5 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3 1.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.3 1.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 0.8 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.3 0.8 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3 2.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 1.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.4 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.2 1.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.6 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 1.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 0.8 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 1.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.8 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.4 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 1.5 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.5 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.7 GO:0072678 T cell migration(GO:0072678)
0.1 0.5 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 1.1 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 1.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.0 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.1 0.2 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.2 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.5 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 0.4 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:0050894 determination of affect(GO:0050894)
0.1 1.3 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296) regulation of mitochondrial DNA metabolic process(GO:1901858)
0.1 0.6 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.1 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 1.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0002884 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.0 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.4 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001) negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 3.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.6 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0043132 NAD transport(GO:0043132)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.4 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.7 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:2001303 cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.4 GO:0090656 t-circle formation(GO:0090656)
0.0 2.5 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.2 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.1 GO:2000232 regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232)
0.0 0.1 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0061767 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 1.9 GO:0007338 single fertilization(GO:0007338)
0.0 0.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0051823 radial glia guided migration of Purkinje cell(GO:0021942) regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 2.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 2.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.7 GO:0045180 basal cortex(GO:0045180)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.6 GO:0032039 integrator complex(GO:0032039)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.5 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 3.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 4.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 3.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 3.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events