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ENCODE cell lines, expression (Ernst 2011)

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Results for SCRT1_SCRT2

Z-value: 1.39

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
SCRT1
ENSG00000170616.9 SCRT1
SCRT2
ENSG00000215397.3 SCRT2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SCRT1hg19_v2_chr8_-_145559943_145559943-0.039.2e-01Click!

Activity profile of SCRT1_SCRT2 motif

Sorted Z-values of SCRT1_SCRT2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_41258786 6.11 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr6_+_121756809 5.26 ENST00000282561.3
 GJA1
 gap junction protein, alpha 1, 43kDa
chr6_-_31697255 4.10 ENST00000436437.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr1_-_95392635 3.66 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
 CNN3
 calponin 3, acidic
chr2_-_175870085 3.61 ENST00000409156.3
 CHN1
 chimerin 1
chr6_-_31697563 3.41 ENST00000375789.2
ENST00000416410.1
 DDAH2
 dimethylarginine dimethylaminohydrolase 2
chr5_+_15500280 2.64 ENST00000504595.1
 FBXL7
 F-box and leucine-rich repeat protein 7
chr1_-_173176452 2.48 ENST00000281834.3
 TNFSF4
 tumor necrosis factor (ligand) superfamily, member 4
chrX_+_51636629 2.21 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
 MAGED1
 melanoma antigen family D, 1
chrX_+_51927919 2.00 ENST00000416960.1
 MAGED4
 melanoma antigen family D, 4
chrX_-_51812268 1.99 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
 MAGED4B
 melanoma antigen family D, 4B
chr7_+_130126165 1.98 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
 MEST
 mesoderm specific transcript
chr7_+_130126012 1.91 ENST00000341441.5
 MEST
 mesoderm specific transcript
chr15_-_30113676 1.73 ENST00000400011.2
 TJP1
 tight junction protein 1
chrX_+_51928002 1.72 ENST00000375626.3
 MAGED4
 melanoma antigen family D, 4
chr11_+_32112431 1.63 ENST00000054950.3
 RCN1
 reticulocalbin 1, EF-hand calcium binding domain
chr4_-_119757239 1.59 ENST00000280551.6
 SEC24D
 SEC24 family member D
chr5_-_111091948 1.52 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr11_+_69455855 1.47 ENST00000227507.2
ENST00000536559.1
 CCND1
 cyclin D1
chr15_-_30114231 1.46 ENST00000356107.6
ENST00000545208.2
 TJP1
 tight junction protein 1
chr4_-_149363662 1.46 ENST00000355292.3
ENST00000358102.3
 NR3C2
 nuclear receptor subfamily 3, group C, member 2
chr3_-_114343768 1.38 ENST00000393785.2
 ZBTB20
 zinc finger and BTB domain containing 20
chr4_-_52904425 1.35 ENST00000535450.1
 SGCB
 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr12_-_13153139 1.34 ENST00000536942.1
ENST00000014930.4
 HEBP1
 heme binding protein 1
chr7_-_122526499 1.23 ENST00000412584.2
 CADPS2
 Ca++-dependent secretion activator 2
chr7_-_122526799 1.17 ENST00000334010.7
ENST00000313070.7
 CADPS2
 Ca++-dependent secretion activator 2
chr1_-_201391149 1.17 ENST00000555948.1
ENST00000556362.1
 TNNI1
 troponin I type 1 (skeletal, slow)
chr19_-_11373128 1.17 ENST00000294618.7
 DOCK6
 dedicator of cytokinesis 6
chr9_+_125703282 1.12 ENST00000373647.4
ENST00000402311.1
 RABGAP1
 RAB GTPase activating protein 1
chr11_+_842928 1.07 ENST00000397408.1
 TSPAN4
 tetraspanin 4
chr19_-_58609570 1.07 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
 ZSCAN18
 zinc finger and SCAN domain containing 18
chr4_-_119757322 1.07 ENST00000379735.5
 SEC24D
 SEC24 family member D
chr1_-_94312706 1.02 ENST00000370244.1
 BCAR3
 breast cancer anti-estrogen resistance 3
chr1_+_150245099 0.99 ENST00000369099.3
 C1orf54
 chromosome 1 open reading frame 54
chr8_+_98881268 0.97 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
 MATN2
 matrilin 2
chr16_+_30383613 0.96 ENST00000568749.1
 MYLPF
 myosin light chain, phosphorylatable, fast skeletal muscle
chr4_-_10118348 0.95 ENST00000502702.1
 WDR1
 WD repeat domain 1
chr20_-_43977055 0.92 ENST00000372733.3
ENST00000537976.1
 SDC4
 syndecan 4
chr12_-_71003568 0.86 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr11_+_842808 0.85 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
 TSPAN4
 tetraspanin 4
chr5_+_72921983 0.84 ENST00000296794.6
ENST00000545377.1
ENST00000513042.2
ENST00000287898.5
ENST00000509848.1
 ARHGEF28
 Rho guanine nucleotide exchange factor (GEF) 28
chr16_-_53537105 0.84 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
 AKTIP
 AKT interacting protein
chr1_-_52456352 0.82 ENST00000371655.3
 RAB3B
 RAB3B, member RAS oncogene family
chr22_-_22090064 0.81 ENST00000339468.3
 YPEL1
 yippee-like 1 (Drosophila)
chr11_-_111794446 0.79 ENST00000527950.1
 CRYAB
 crystallin, alpha B
chr1_+_109289279 0.76 ENST00000370008.3
 STXBP3
 syntaxin binding protein 3
chr11_-_61659006 0.72 ENST00000278829.2
 FADS3
 fatty acid desaturase 3
chrX_+_15518923 0.68 ENST00000348343.6
 BMX
 BMX non-receptor tyrosine kinase
chr10_-_101945771 0.67 ENST00000370408.2
ENST00000407654.3
 ERLIN1
 ER lipid raft associated 1
chr5_+_125758813 0.65 ENST00000285689.3
ENST00000515200.1
 GRAMD3
 GRAM domain containing 3
chr7_+_99699280 0.64 ENST00000421755.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr6_-_83903600 0.63 ENST00000506587.1
ENST00000507554.1
 PGM3
 phosphoglucomutase 3
chr5_+_125758865 0.62 ENST00000542322.1
ENST00000544396.1
 GRAMD3
 GRAM domain containing 3
chr11_+_65779283 0.58 ENST00000312134.2
 CST6
 cystatin E/M
chr11_+_6624955 0.56 ENST00000299421.4
ENST00000537806.1
 ILK
 integrin-linked kinase
chr2_-_24583583 0.56 ENST00000355123.4
 ITSN2
 intersectin 2
chr7_+_99699179 0.56 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr21_-_35987438 0.54 ENST00000313806.4
 RCAN1
 regulator of calcineurin 1
chr1_+_110162448 0.51 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
 AMPD2
 adenosine monophosphate deaminase 2
chr4_+_41540160 0.51 ENST00000503057.1
ENST00000511496.1
 LIMCH1
 LIM and calponin homology domains 1
chr11_+_6624970 0.50 ENST00000420936.2
ENST00000528995.1
 ILK
 integrin-linked kinase
chr13_+_58206655 0.49 ENST00000377918.3
 PCDH17
 protocadherin 17
chr2_-_178753465 0.48 ENST00000389683.3
 PDE11A
 phosphodiesterase 11A
chr17_-_33760164 0.46 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
 SLFN12
 schlafen family member 12
chr5_-_73936451 0.44 ENST00000537006.1
 ENC1
 ectodermal-neural cortex 1 (with BTB domain)
chr14_+_67708137 0.44 ENST00000556345.1
ENST00000555925.1
ENST00000557783.1
 MPP5
 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr14_+_102829300 0.44 ENST00000359520.7
 TECPR2
 tectonin beta-propeller repeat containing 2
chr11_-_117747607 0.43 ENST00000540359.1
ENST00000539526.1
 FXYD6
 FXYD domain containing ion transport regulator 6
chr11_-_117748138 0.42 ENST00000527717.1
 FXYD6
 FXYD domain containing ion transport regulator 6
chr17_-_33760269 0.41 ENST00000452764.3
 SLFN12
 schlafen family member 12
chr5_+_32710736 0.41 ENST00000415685.2
 NPR3
 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr4_-_141348789 0.40 ENST00000414773.1
 CLGN
 calmegin
chr8_-_116681221 0.40 ENST00000395715.3
 TRPS1
 trichorhinophalangeal syndrome I
chrX_+_55744228 0.39 ENST00000262850.7
 RRAGB
 Ras-related GTP binding B
chr19_+_40877583 0.39 ENST00000596470.1
 PLD3
 phospholipase D family, member 3
chr20_+_57427765 0.38 ENST00000371100.4
 GNAS
 GNAS complex locus
chr7_+_12727250 0.38 ENST00000404894.1
 ARL4A
 ADP-ribosylation factor-like 4A
chr9_+_114423615 0.37 ENST00000374293.4
 GNG10
 guanine nucleotide binding protein (G protein), gamma 10
chr4_-_5890145 0.37 ENST00000397890.2
 CRMP1
 collapsin response mediator protein 1
chr9_+_99212403 0.36 ENST00000375251.3
ENST00000375249.4
 HABP4
 hyaluronan binding protein 4
chr5_+_138089100 0.36 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
chr4_-_10117949 0.35 ENST00000508079.1
 WDR1
 WD repeat domain 1
chr11_+_61583721 0.34 ENST00000257261.6
 FADS2
 fatty acid desaturase 2
chr3_-_146187088 0.34 ENST00000497985.1
 PLSCR2
 phospholipid scramblase 2
chr3_-_79816965 0.33 ENST00000464233.1
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr3_+_10857885 0.33 ENST00000254488.2
ENST00000454147.1
 SLC6A11
 solute carrier family 6 (neurotransmitter transporter), member 11
chr14_+_67707826 0.33 ENST00000261681.4
 MPP5
 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr22_-_22090043 0.33 ENST00000403503.1
 YPEL1
 yippee-like 1 (Drosophila)
chr19_-_46974741 0.32 ENST00000313683.10
ENST00000602246.1
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr2_-_24583314 0.31 ENST00000443927.1
ENST00000406921.3
ENST00000412011.1
 ITSN2
 intersectin 2
chr19_-_46974664 0.30 ENST00000438932.2
 PNMAL1
 paraneoplastic Ma antigen family-like 1
chr5_-_59064458 0.30 ENST00000502575.1
ENST00000507116.1
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr5_+_74011328 0.30 ENST00000513336.1
 HEXB
 hexosaminidase B (beta polypeptide)
chr16_-_30022293 0.29 ENST00000565273.1
ENST00000567332.2
ENST00000350119.4
 DOC2A
 double C2-like domains, alpha
chr14_+_23775971 0.28 ENST00000250405.5
 BCL2L2
 BCL2-like 2
chr3_+_133465228 0.25 ENST00000482271.1
ENST00000264998.3
 TF
 transferrin
chr8_+_22429205 0.25 ENST00000520207.1
 SORBS3
 sorbin and SH3 domain containing 3
chr1_-_154928562 0.25 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
 PBXIP1
 pre-B-cell leukemia homeobox interacting protein 1
chr3_+_141144954 0.24 ENST00000441582.2
ENST00000321464.5
 ZBTB38
 zinc finger and BTB domain containing 38
chr11_+_27062272 0.24 ENST00000529202.1
ENST00000533566.1
 BBOX1
 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_-_212588157 0.24 ENST00000261455.4
ENST00000535273.1
 TMEM206
 transmembrane protein 206
chr9_-_116840728 0.22 ENST00000265132.3
 AMBP
 alpha-1-microglobulin/bikunin precursor
chr6_+_28092338 0.22 ENST00000340487.4
 ZSCAN16
 zinc finger and SCAN domain containing 16
chr17_-_79805146 0.21 ENST00000415593.1
 P4HB
 prolyl 4-hydroxylase, beta polypeptide
chr12_+_81471816 0.20 ENST00000261206.3
 ACSS3
 acyl-CoA synthetase short-chain family member 3
chr6_+_71122974 0.20 ENST00000418814.2
 FAM135A
 family with sequence similarity 135, member A
chr2_-_224467093 0.19 ENST00000305409.2
 SCG2
 secretogranin II
chr7_+_114562172 0.19 ENST00000393486.1
ENST00000257724.3
 MDFIC
 MyoD family inhibitor domain containing
chr17_-_32484313 0.18 ENST00000359872.6
 ASIC2
 acid-sensing (proton-gated) ion channel 2
chr19_-_5838768 0.17 ENST00000527106.1
ENST00000531199.1
ENST00000529165.1
 FUT6
 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr4_+_980785 0.17 ENST00000247933.4
ENST00000453894.1
 IDUA
 iduronidase, alpha-L-
chr1_+_44115814 0.16 ENST00000372396.3
 KDM4A
 lysine (K)-specific demethylase 4A
chr8_+_132952112 0.16 ENST00000520362.1
ENST00000519656.1
 EFR3A
 EFR3 homolog A (S. cerevisiae)
chrX_+_118370211 0.16 ENST00000217971.7
 PGRMC1
 progesterone receptor membrane component 1
chr3_-_186080012 0.15 ENST00000544847.1
ENST00000265022.3
 DGKG
 diacylglycerol kinase, gamma 90kDa
chr11_-_117747434 0.15 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
 FXYD6
 FXYD domain containing ion transport regulator 6
chr12_-_57824739 0.14 ENST00000347140.3
ENST00000402412.1
 R3HDM2
 R3H domain containing 2
chr4_-_120133661 0.14 ENST00000503243.1
ENST00000326780.3
 RP11-455G16.1
 Uncharacterized protein
chr9_+_100174344 0.13 ENST00000422139.2
 TDRD7
 tudor domain containing 7
chr1_-_156918806 0.13 ENST00000315174.8
 ARHGEF11
 Rho guanine nucleotide exchange factor (GEF) 11
chr6_+_108977520 0.13 ENST00000540898.1
 FOXO3
 forkhead box O3
chr16_+_25123041 0.12 ENST00000399069.3
ENST00000380966.4
 LCMT1
 leucine carboxyl methyltransferase 1
chr6_-_31080336 0.12 ENST00000259870.3
 C6orf15
 chromosome 6 open reading frame 15
chr22_+_40742512 0.12 ENST00000454266.2
ENST00000342312.6
 ADSL
 adenylosuccinate lyase
chr17_-_2415169 0.11 ENST00000263092.6
ENST00000538844.1
ENST00000576976.1
 METTL16
 methyltransferase like 16
chr19_-_18391708 0.11 ENST00000600972.1
 JUND
 jun D proto-oncogene
chr17_-_40288449 0.11 ENST00000552162.1
ENST00000550504.1
 RAB5C
 RAB5C, member RAS oncogene family
chr3_-_62861012 0.11 ENST00000357948.3
ENST00000383710.4
 CADPS
 Ca++-dependent secretion activator
chr15_+_84904525 0.10 ENST00000510439.2
 GOLGA6L4
 golgin A6 family-like 4
chr2_-_167232484 0.10 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
 SCN9A
 sodium channel, voltage-gated, type IX, alpha subunit
chr16_-_25122785 0.10 ENST00000563962.1
ENST00000569920.1
 RP11-449H11.1
 RP11-449H11.1
chr17_+_63133587 0.10 ENST00000449996.3
ENST00000262406.9
 RGS9
 regulator of G-protein signaling 9
chr10_-_95209 0.10 ENST00000332708.5
ENST00000309812.4
 TUBB8
 tubulin, beta 8 class VIII
chr1_-_224033596 0.09 ENST00000391878.2
ENST00000343537.7
 TP53BP2
 tumor protein p53 binding protein, 2
chr1_+_225965518 0.08 ENST00000304786.7
ENST00000366839.4
ENST00000366838.1
 SRP9
 signal recognition particle 9kDa
chr15_+_80351910 0.08 ENST00000261749.6
ENST00000561060.1
 ZFAND6
 zinc finger, AN1-type domain 6
chr1_-_222885770 0.08 ENST00000355727.2
ENST00000340020.6
 AIDA
 axin interactor, dorsalization associated
chr12_+_103981044 0.07 ENST00000388887.2
 STAB2
 stabilin 2
chr1_+_43148625 0.07 ENST00000436427.1
 YBX1
 Y box binding protein 1
chr7_+_94536898 0.07 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
 PPP1R9A
 protein phosphatase 1, regulatory subunit 9A
chr2_+_173600671 0.06 ENST00000409036.1
 RAPGEF4
 Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_122907091 0.06 ENST00000358808.2
ENST00000361654.4
ENST00000539080.1
ENST00000537178.1
 CLIP1
 CAP-GLY domain containing linker protein 1
chr21_-_34852304 0.06 ENST00000542230.2
 TMEM50B
 transmembrane protein 50B
chr10_-_47222824 0.05 ENST00000355232.3
 AGAP10
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr8_+_145438870 0.05 ENST00000527931.1
 FAM203B
 family with sequence similarity 203, member B
chr4_+_87856191 0.04 ENST00000503477.1
 AFF1
 AF4/FMR2 family, member 1
chr8_-_101718991 0.03 ENST00000517990.1
 PABPC1
 poly(A) binding protein, cytoplasmic 1
chr19_+_30097181 0.03 ENST00000586420.1
ENST00000221770.3
ENST00000392279.3
ENST00000590688.1
 POP4
 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
chr12_-_117318788 0.03 ENST00000550505.1
 HRK
 harakiri, BCL2 interacting protein (contains only BH3 domain)
chr6_-_34113856 0.02 ENST00000538487.2
 GRM4
 glutamate receptor, metabotropic 4
chr1_-_204135450 0.02 ENST00000272190.8
ENST00000367195.2
 REN
 renin
chr19_+_52264104 0.01 ENST00000340023.6
 FPR2
 formyl peptide receptor 2
chr5_+_173763250 0.01 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
 RP11-267A15.1
 RP11-267A15.1
chr6_+_71123107 0.01 ENST00000370479.3
ENST00000505769.1
ENST00000515323.1
ENST00000515280.1
ENST00000507085.1
ENST00000457062.2
ENST00000361499.3
 FAM135A
 family with sequence similarity 135, member A
chr22_-_19466732 0.01 ENST00000263202.10
ENST00000360834.4
 UFD1L
 ubiquitin fusion degradation 1 like (yeast)
chr19_+_12862604 0.00 ENST00000553030.1
 BEST2
 bestrophin 2

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 4.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 5.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 4.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0007412 axon target recognition(GO:0007412)
1.8 5.3 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.1 3.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.8 2.5 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.5 2.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.5 7.5 GO:0006527 arginine catabolic process(GO:0006527)
0.3 1.3 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.3 2.6 GO:0010265 SCF complex assembly(GO:0010265)
0.2 1.1 GO:0007623 circadian rhythm(GO:0007623)
0.2 0.9 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 0.8 GO:0051582 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.2 3.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.5 GO:0070141 response to UV-A(GO:0070141)
0.1 0.7 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.6 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.4 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.1 3.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 2.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.8 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 2.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.8 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1 0.5 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 1.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.7 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:0007619 courtship behavior(GO:0007619)
0.1 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.1 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.6 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 3.9 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.8 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.2 GO:1900113 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 1.0 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.1 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.7 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 2.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 2.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.5 7.5 GO:0016403 dimethylargininase activity(GO:0016403)
1.1 5.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 2.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 3.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.3 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 3.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.6 GO:0000149 SNARE binding(GO:0000149)
0.0 2.2 GO:0005496 steroid binding(GO:0005496)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 3.2 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 GO:0005916 fascia adherens(GO:0005916)
0.3 1.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 0.8 GO:0070695 FHF complex(GO:0070695)
0.2 1.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 5.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 3.2 GO:0005921 gap junction(GO:0005921)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0001533 cornified envelope(GO:0001533)
0.1 0.8 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.2 GO:0005861 troponin complex(GO:0005861)
0.1 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 7.8 GO:0005815 microtubule organizing center(GO:0005815)