ISMARA results: SHOX2

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ENCODE cell lines, expression (Ernst 2011)

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Results for SHOX2_HOXC5

Z-value: 1.20

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Transcription factors associated with SHOX2_HOXC5

Gene Symbol	Gene ID	Gene Info
SHOX2 Ensembl NCBI GeneCards UniProt	ENSG00000168779.15	SHOX2
HOXC5 Ensembl NCBI GeneCards UniProt	ENSG00000172789.3	HOXC5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXC5	hg19_v2_chr12_+_54426637_54426637	-0.33	2.1e-01	Click!
SHOX2	hg19_v2_chr3_-_157824292_157824334	-0.16	5.6e-01	Click!

Activity profile of SHOX2_HOXC5 motif

Sorted Z-values of SHOX2_HOXC5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX2_HOXC5

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr7_-_87856280	5.20	ENST00000490437.1 ENST00000431660.1	SRI	sorcin
chr7_-_87856303	4.98	ENST00000394641.3	SRI	sorcin
chr11_+_5710919	2.90	ENST00000379965.3 ENST00000425490.1	TRIM22	tripartite motif containing 22
chr11_+_2405833	2.87	ENST00000527343.1 ENST00000464784.2	CD81	CD81 molecule
chr21_-_15918618	2.74	ENST00000400564.1 ENST00000400566.1	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_33913708	2.71	ENST00000257818.2	LMO2	LIM domain only 2 (rhombotin-like 1)
chr7_+_102553430	2.47	ENST00000339431.4 ENST00000249377.4	LRRC17	leucine rich repeat containing 17
chr15_-_20193370	2.40	ENST00000558565.2	IGHV3OR15-7	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr12_-_91546926	2.38	ENST00000550758.1	DCN	decorin
chr1_-_153518270	2.34	ENST00000354332.4 ENST00000368716.4	S100A4	S100 calcium binding protein A4
chr2_-_238323007	2.34	ENST00000295550.4	COL6A3	collagen, type VI, alpha 3
chr12_-_10022735	2.26	ENST00000228438.2	CLEC2B	C-type lectin domain family 2, member B
chr11_+_35201826	2.13	ENST00000531873.1	CD44	CD44 molecule (Indian blood group)
chr3_-_141747950	2.05	ENST00000497579.1	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr22_+_21996549	2.05	ENST00000248958.4	SDF2L1	stromal cell-derived factor 2-like 1
chr7_+_107224364	2.03	ENST00000491150.1	BCAP29	B-cell receptor-associated protein 29
chr12_-_91573249	2.01	ENST00000550099.1 ENST00000546391.1 ENST00000551354.1	DCN	decorin
chr6_-_32557610	1.90	ENST00000360004.5	HLA-DRB1	major histocompatibility complex, class II, DR beta 1
chr12_+_48513009	1.84	ENST00000359794.5 ENST00000551339.1 ENST00000395233.2 ENST00000548345.1	PFKM	phosphofructokinase, muscle
chr6_+_116601265	1.71	ENST00000452085.3	DSE	dermatan sulfate epimerase
chr14_-_106668095	1.66	ENST00000390606.2	IGHV3-20	immunoglobulin heavy variable 3-20
chr2_-_225811747	1.63	ENST00000409592.3	DOCK10	dedicator of cytokinesis 10
chr12_+_26348246	1.60	ENST00000422622.2	SSPN	sarcospan
chr14_-_106552755	1.45	ENST00000390600.2	IGHV3-9	immunoglobulin heavy variable 3-9
chr12_+_26348429	1.44	ENST00000242729.2	SSPN	sarcospan
chr1_-_145076186	1.44	ENST00000369348.3	PDE4DIP	phosphodiesterase 4D interacting protein
chr6_-_26235206	1.44	ENST00000244534.5	HIST1H1D	histone cluster 1, H1d
chr7_-_144533074	1.43	ENST00000360057.3 ENST00000378099.3	TPK1	thiamin pyrophosphokinase 1
chr2_-_238322770	1.42	ENST00000472056.1	COL6A3	collagen, type VI, alpha 3
chr7_+_120628731	1.41	ENST00000310396.5	CPED1	cadherin-like and PC-esterase domain containing 1
chr12_-_91573132	1.41	ENST00000550563.1 ENST00000546370.1	DCN	decorin
chr3_+_157154578	1.29	ENST00000295927.3	PTX3	pentraxin 3, long
chr2_+_90077680	1.27	ENST00000390270.2	IGKV3D-20	immunoglobulin kappa variable 3D-20
chr17_+_67498538	1.24	ENST00000589647.1	MAP2K6	mitogen-activated protein kinase kinase 6
chr6_+_13272904	1.19	ENST00000379335.3 ENST00000379329.1	PHACTR1	phosphatase and actin regulator 1
chr2_-_238322800	1.17	ENST00000392004.3 ENST00000433762.1 ENST00000347401.3 ENST00000353578.4 ENST00000346358.4 ENST00000392003.2	COL6A3	collagen, type VI, alpha 3
chr4_-_69536346	1.17	ENST00000338206.5	UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15
chr4_-_47465666	1.16	ENST00000381571.4	COMMD8	COMM domain containing 8
chr7_+_120591170	1.16	ENST00000431467.1	ING3	inhibitor of growth family, member 3
chr11_-_71823715	1.14	ENST00000545944.1 ENST00000502597.2	ANAPC15	anaphase promoting complex subunit 15
chr16_+_12059091	1.12	ENST00000562385.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chrX_-_154033661	1.12	ENST00000393531.1	MPP1	membrane protein, palmitoylated 1, 55kDa
chr2_-_211179883	1.10	ENST00000352451.3	MYL1	myosin, light chain 1, alkali; skeletal, fast
chrX_+_65382433	1.10	ENST00000374727.3	HEPH	hephaestin
chr1_+_51434357	1.09	ENST00000396148.1	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr16_+_12059050	1.07	ENST00000396495.3	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr1_-_54411255	1.05	ENST00000371377.3	HSPB11	heat shock protein family B (small), member 11
chr2_+_189839046	1.05	ENST00000304636.3 ENST00000317840.5	COL3A1	collagen, type III, alpha 1
chr7_-_102184083	1.04	ENST00000379357.5	POLR2J3	polymerase (RNA) II (DNA directed) polypeptide J3
chr1_-_193075180	1.04	ENST00000367440.3	GLRX2	glutaredoxin 2
chr3_-_141719195	1.02	ENST00000397991.4	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr14_-_107049312	1.02	ENST00000390627.2	IGHV3-53	immunoglobulin heavy variable 3-53
chrX_-_100872911	1.02	ENST00000361910.4 ENST00000539247.1 ENST00000538627.1	ARMCX6	armadillo repeat containing, X-linked 6
chr3_-_16524357	1.02	ENST00000432519.1	RFTN1	raftlin, lipid raft linker 1
chr8_-_38008783	1.01	ENST00000276449.4	STAR	steroidogenic acute regulatory protein
chr2_-_87248975	0.99	ENST00000409310.2 ENST00000355705.3	PLGLB1	plasminogen-like B1
chr5_+_53751445	0.98	ENST00000302005.1	HSPB3	heat shock 27kDa protein 3
chr16_+_32077386	0.98	ENST00000354689.6	IGHV3OR16-9	immunoglobulin heavy variable 3/OR16-9 (non-functional)
chrX_+_51486481	0.97	ENST00000340438.4	GSPT2	G1 to S phase transition 2
chr1_-_39339777	0.97	ENST00000397572.2	MYCBP	MYC binding protein
chr15_+_64680003	0.95	ENST00000261884.3	TRIP4	thyroid hormone receptor interactor 4
chr3_+_37035289	0.95	ENST00000455445.2 ENST00000441265.1 ENST00000435176.1 ENST00000429117.1 ENST00000536378.1	MLH1	mutL homolog 1
chr8_-_90996837	0.93	ENST00000519426.1 ENST00000265433.3	NBN	nibrin
chr11_+_114168085	0.92	ENST00000541754.1	NNMT	nicotinamide N-methyltransferase
chr6_-_41909561	0.92	ENST00000372991.4	CCND3	cyclin D3
chr12_-_91573316	0.91	ENST00000393155.1	DCN	decorin
chr12_-_772901	0.91	ENST00000305108.4	NINJ2	ninjurin 2
chr1_-_67266939	0.90	ENST00000304526.2	INSL5	insulin-like 5
chr5_+_89770696	0.89	ENST00000504930.1 ENST00000514483.1	POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr4_+_169418195	0.89	ENST00000261509.6 ENST00000335742.7	PALLD	palladin, cytoskeletal associated protein
chr4_-_76928641	0.87	ENST00000264888.5	CXCL9	chemokine (C-X-C motif) ligand 9
chrX_+_77166172	0.87	ENST00000343533.5 ENST00000350425.4 ENST00000341514.6	ATP7A	ATPase, Cu++ transporting, alpha polypeptide
chr8_-_90996459	0.86	ENST00000517337.1 ENST00000409330.1	NBN	nibrin
chrX_-_92928557	0.85	ENST00000373079.3 ENST00000475430.2	NAP1L3	nucleosome assembly protein 1-like 3
chr1_+_43291220	0.84	ENST00000372514.3	ERMAP	erythroblast membrane-associated protein (Scianna blood group)
chr14_-_100841930	0.84	ENST00000555031.1 ENST00000553395.1 ENST00000553545.1 ENST00000344102.5 ENST00000556338.1 ENST00000392882.2 ENST00000553934.1	WARS	tryptophanyl-tRNA synthetase
chr14_-_106926724	0.83	ENST00000434710.1	IGHV3-43	immunoglobulin heavy variable 3-43
chr11_-_27722021	0.82	ENST00000356660.4 ENST00000418212.1 ENST00000533246.1	BDNF	brain-derived neurotrophic factor
chr6_+_26199737	0.82	ENST00000359985.1	HIST1H2BF	histone cluster 1, H2bf
chr1_+_158801095	0.82	ENST00000368141.4	MNDA	myeloid cell nuclear differentiation antigen
chr12_+_75874984	0.81	ENST00000550491.1	GLIPR1	GLI pathogenesis-related 1
chr18_-_53177984	0.81	ENST00000543082.1	TCF4	transcription factor 4
chr1_-_114414316	0.80	ENST00000528414.1 ENST00000538253.1 ENST00000460620.1 ENST00000420377.2 ENST00000525799.1 ENST00000359785.5	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr12_+_75874580	0.80	ENST00000456650.3	GLIPR1	GLI pathogenesis-related 1
chr7_-_64023441	0.79	ENST00000309683.6	ZNF680	zinc finger protein 680
chr13_-_110438914	0.79	ENST00000375856.3	IRS2	insulin receptor substrate 2
chr14_-_106573756	0.78	ENST00000390601.2	IGHV3-11	immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr3_-_158390282	0.77	ENST00000264265.3	LXN	latexin
chr2_-_158345462	0.77	ENST00000439355.1 ENST00000540637.1	CYTIP	cytohesin 1 interacting protein
chr11_-_63376013	0.76	ENST00000540943.1	PLA2G16	phospholipase A2, group XVI
chr5_+_89770664	0.76	ENST00000503973.1 ENST00000399107.1	POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr11_-_104972158	0.76	ENST00000598974.1 ENST00000593315.1 ENST00000594519.1 ENST00000415981.2 ENST00000525374.1 ENST00000375707.1	CASP1 CARD16 CARD17	caspase 1, apoptosis-related cysteine peptidase caspase recruitment domain family, member 16 caspase recruitment domain family, member 17
chr4_-_72649763	0.76	ENST00000513476.1	GC	group-specific component (vitamin D binding protein)
chr22_-_32766972	0.76	ENST00000382084.4 ENST00000382086.2	RFPL3S	RFPL3 antisense
chr10_+_96522361	0.75	ENST00000371321.3	CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
chr12_-_91572278	0.75	ENST00000425043.1 ENST00000420120.2 ENST00000441303.2 ENST00000456569.2	DCN	decorin
chr1_+_158979792	0.75	ENST00000359709.3 ENST00000430894.2	IFI16	interferon, gamma-inducible protein 16
chrX_+_107334895	0.75	ENST00000372232.3 ENST00000345734.3 ENST00000372254.3	ATG4A	autophagy related 4A, cysteine peptidase
chr12_-_15114603	0.74	ENST00000228945.4	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chrX_+_30261847	0.74	ENST00000378981.3 ENST00000397550.1	MAGEB1	melanoma antigen family B, 1
chr1_+_158979680	0.73	ENST00000368131.4 ENST00000340979.6	IFI16	interferon, gamma-inducible protein 16
chr2_-_175712270	0.72	ENST00000295497.7 ENST00000444394.1	CHN1	chimerin 1
chr1_+_158979686	0.71	ENST00000368132.3 ENST00000295809.7	IFI16	interferon, gamma-inducible protein 16
chr8_-_95487331	0.71	ENST00000336148.5	RAD54B	RAD54 homolog B (S. cerevisiae)
chr5_-_10761206	0.71	ENST00000432074.2 ENST00000230895.6	DAP	death-associated protein
chr6_+_32407619	0.70	ENST00000395388.2 ENST00000374982.5	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr12_+_81110684	0.70	ENST00000228644.3	MYF5	myogenic factor 5
chr11_+_59824127	0.70	ENST00000278865.3	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr5_-_55412774	0.70	ENST00000434982.2	ANKRD55	ankyrin repeat domain 55
chr7_+_93551011	0.70	ENST00000248564.5	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr12_-_8803128	0.70	ENST00000543467.1	MFAP5	microfibrillar associated protein 5
chr2_+_90153696	0.69	ENST00000417279.2	IGKV3D-15	immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr1_+_160709055	0.69	ENST00000368043.3 ENST00000368042.3 ENST00000458602.2 ENST00000458104.2	SLAMF7	SLAM family member 7
chr5_+_119799927	0.69	ENST00000407149.2 ENST00000379551.2	PRR16	proline rich 16
chr15_-_72563585	0.69	ENST00000287196.9 ENST00000260376.7	PARP6	poly (ADP-ribose) polymerase family, member 6
chr2_-_89292422	0.68	ENST00000495489.1	IGKV1-8	immunoglobulin kappa variable 1-8
chr3_+_148709128	0.68	ENST00000345003.4 ENST00000296048.6 ENST00000483267.1	GYG1	glycogenin 1
chr11_-_5255861	0.68	ENST00000380299.3	HBD	hemoglobin, delta
chr2_-_89385283	0.67	ENST00000390252.2	IGKV3-15	immunoglobulin kappa variable 3-15
chr5_+_119867159	0.67	ENST00000505123.1	PRR16	proline rich 16
chrX_-_77225135	0.67	ENST00000458128.1	PGAM4	phosphoglycerate mutase family member 4
chr2_+_88047606	0.67	ENST00000359481.4	PLGLB2	plasminogen-like B2
chr10_-_49860525	0.67	ENST00000435790.2	ARHGAP22	Rho GTPase activating protein 22
chr12_+_75874460	0.66	ENST00000266659.3	GLIPR1	GLI pathogenesis-related 1
chr1_+_78470530	0.66	ENST00000370763.5	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_164796269	0.66	ENST00000264382.3	SI	sucrase-isomaltase (alpha-glucosidase)
chr1_+_160709029	0.66	ENST00000444090.2 ENST00000441662.2	SLAMF7	SLAM family member 7
chr1_-_183559693	0.65	ENST00000367535.3 ENST00000413720.1 ENST00000418089.1	NCF2	neutrophil cytosolic factor 2
chr2_-_136633940	0.65	ENST00000264156.2	MCM6	minichromosome maintenance complex component 6
chr2_-_191115229	0.65	ENST00000409820.2 ENST00000410045.1	HIBCH	3-hydroxyisobutyryl-CoA hydrolase
chr7_-_22862406	0.65	ENST00000372879.4	TOMM7	translocase of outer mitochondrial membrane 7 homolog (yeast)
chrX_-_17879356	0.64	ENST00000331511.1 ENST00000415486.3 ENST00000545871.1 ENST00000451717.1	RAI2	retinoic acid induced 2
chr21_-_35284635	0.64	ENST00000429238.1	AP000304.12	AP000304.12
chr11_+_57480046	0.64	ENST00000378312.4 ENST00000278422.4	TMX2	thioredoxin-related transmembrane protein 2
chr15_+_67418047	0.64	ENST00000540846.2	SMAD3	SMAD family member 3
chr1_-_35450897	0.64	ENST00000373337.3	ZMYM6NB	ZMYM6 neighbor
chr15_-_75248954	0.63	ENST00000499788.2	RPP25	ribonuclease P/MRP 25kDa subunit
chr4_+_113568207	0.63	ENST00000511529.1	LARP7	La ribonucleoprotein domain family, member 7
chr10_-_28571015	0.61	ENST00000375719.3 ENST00000375732.1	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr3_-_156272924	0.61	ENST00000467789.1 ENST00000265044.2	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)
chr10_+_35484793	0.61	ENST00000488741.1 ENST00000474931.1 ENST00000468236.1 ENST00000344351.5 ENST00000490511.1	CREM	cAMP responsive element modulator
chr5_+_140227357	0.60	ENST00000378122.3	PCDHA9	protocadherin alpha 9
chr7_-_37024665	0.60	ENST00000396040.2	ELMO1	engulfment and cell motility 1
chr16_+_1359511	0.60	ENST00000397514.3 ENST00000397515.2 ENST00000567383.1 ENST00000403747.2 ENST00000566587.1	UBE2I	ubiquitin-conjugating enzyme E2I
chr2_-_175547571	0.60	ENST00000409415.3 ENST00000359761.3 ENST00000272746.5	WIPF1	WAS/WASL interacting protein family, member 1
chr4_+_169418255	0.60	ENST00000505667.1 ENST00000511948.1	PALLD	palladin, cytoskeletal associated protein
chr1_-_160681593	0.59	ENST00000368045.3 ENST00000368046.3	CD48	CD48 molecule
chr12_-_9913489	0.59	ENST00000228434.3 ENST00000536709.1	CD69	CD69 molecule
chr9_-_128246769	0.59	ENST00000444226.1	MAPKAP1	mitogen-activated protein kinase associated protein 1
chr2_-_158300556	0.58	ENST00000264192.3	CYTIP	cytohesin 1 interacting protein
chr6_-_144385698	0.58	ENST00000444202.1 ENST00000437412.1	PLAGL1	pleiomorphic adenoma gene-like 1
chr4_+_40198527	0.57	ENST00000381799.5	RHOH	ras homolog family member H
chr7_-_150020578	0.57	ENST00000478393.1	ACTR3C	ARP3 actin-related protein 3 homolog C (yeast)
chr1_+_150480576	0.56	ENST00000346569.6	ECM1	extracellular matrix protein 1
chrX_+_47444613	0.56	ENST00000445623.1	TIMP1	TIMP metallopeptidase inhibitor 1
chr6_+_110501344	0.56	ENST00000368932.1	CDC40	cell division cycle 40
chrX_+_135230712	0.56	ENST00000535737.1	FHL1	four and a half LIM domains 1
chr4_-_120243545	0.56	ENST00000274024.3	FABP2	fatty acid binding protein 2, intestinal
chr19_-_39826639	0.55	ENST00000602185.1 ENST00000598034.1 ENST00000601387.1 ENST00000595636.1 ENST00000253054.8 ENST00000594700.1 ENST00000597595.1	GMFG	glia maturation factor, gamma
chr5_-_143550241	0.55	ENST00000522203.1	YIPF5	Yip1 domain family, member 5
chr5_-_94417339	0.55	ENST00000429576.2 ENST00000508509.1 ENST00000510732.1	MCTP1	multiple C2 domains, transmembrane 1
chr11_+_33061543	0.55	ENST00000432887.1 ENST00000528898.1 ENST00000531632.2	TCP11L1	t-complex 11, testis-specific-like 1
chr8_-_95487272	0.54	ENST00000297592.5	RAD54B	RAD54 homolog B (S. cerevisiae)
chrX_+_7137475	0.54	ENST00000217961.4	STS	steroid sulfatase (microsomal), isozyme S
chr12_+_94071341	0.54	ENST00000542893.2	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain
chr1_-_150738261	0.54	ENST00000448301.2 ENST00000368985.3	CTSS	cathepsin S
chr19_-_43382142	0.54	ENST00000597058.1	PSG1	pregnancy specific beta-1-glycoprotein 1
chr22_+_40297079	0.54	ENST00000344138.4 ENST00000543252.1	GRAP2	GRB2-related adaptor protein 2
chr1_-_197115818	0.54	ENST00000367409.4 ENST00000294732.7	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chrX_+_78200829	0.53	ENST00000544091.1	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr15_-_55657428	0.53	ENST00000568543.1	CCPG1	cell cycle progression 1
chr5_-_143550159	0.53	ENST00000448443.2 ENST00000513112.1 ENST00000519064.1 ENST00000274496.5	YIPF5	Yip1 domain family, member 5
chr17_-_45266542	0.53	ENST00000531206.1 ENST00000527547.1 ENST00000446365.2 ENST00000575483.1 ENST00000066544.3	CDC27	cell division cycle 27
chr1_+_196788887	0.53	ENST00000320493.5 ENST00000367424.4 ENST00000367421.3	CFHR1 CFHR2	complement factor H-related 1 complement factor H-related 2
chr9_+_125132803	0.52	ENST00000540753.1	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr22_+_23134974	0.52	ENST00000390314.2	IGLV2-11	immunoglobulin lambda variable 2-11
chr18_-_67624160	0.52	ENST00000581982.1 ENST00000280200.4	CD226	CD226 molecule
chr12_-_15038779	0.52	ENST00000228938.5 ENST00000539261.1	MGP	matrix Gla protein
chr11_+_59824060	0.51	ENST00000395032.2 ENST00000358152.2	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr16_+_33204156	0.51	ENST00000398667.4	TP53TG3C	TP53 target 3C
chr8_+_98900132	0.51	ENST00000520016.1	MATN2	matrilin 2
chr3_-_160823040	0.50	ENST00000484127.1 ENST00000492353.1 ENST00000473142.1 ENST00000468268.1 ENST00000460353.1 ENST00000320474.4 ENST00000392781.2	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_192544857	0.50	ENST00000367459.3 ENST00000469578.2	RGS1	regulator of G-protein signaling 1
chr2_-_89521942	0.50	ENST00000482769.1	IGKV2-28	immunoglobulin kappa variable 2-28
chr1_-_6420737	0.50	ENST00000541130.1 ENST00000377845.3	ACOT7	acyl-CoA thioesterase 7
chrX_+_49294472	0.50	ENST00000361446.5	GAGE12B	G antigen 12B
chr4_-_164534657	0.50	ENST00000339875.5	MARCH1	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr6_-_161085291	0.50	ENST00000316300.5	LPA	lipoprotein, Lp(a)
chr2_+_90139056	0.50	ENST00000492446.1	IGKV1D-16	immunoglobulin kappa variable 1D-16
chr2_-_90538397	0.49	ENST00000443397.3	RP11-685N3.1	Uncharacterized protein
chr2_+_152214098	0.49	ENST00000243347.3	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr9_+_117373486	0.49	ENST00000288502.4 ENST00000374049.4	C9orf91	chromosome 9 open reading frame 91
chrX_+_78200913	0.48	ENST00000171757.2	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr2_+_87565634	0.48	ENST00000421835.2	IGKV3OR2-268	immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr1_-_197036364	0.48	ENST00000367412.1	F13B	coagulation factor XIII, B polypeptide
chr7_-_123197733	0.48	ENST00000470123.1 ENST00000471770.1	NDUFA5	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr6_-_57086200	0.48	ENST00000468148.1	RAB23	RAB23, member RAS oncogene family
chr1_-_193074504	0.47	ENST00000367439.3	GLRX2	glutaredoxin 2
chr4_+_110736659	0.47	ENST00000394631.3 ENST00000226796.6	GAR1	GAR1 ribonucleoprotein
chr4_-_57547870	0.47	ENST00000381260.3 ENST00000420433.1 ENST00000554144.1 ENST00000557328.1	HOPX	HOP homeobox

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	2.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	6.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	1.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	1.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	4.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	0.7	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	1.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	3.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	2.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.4	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	1.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.7	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.8	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	1.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	1.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.6	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.7	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	1.4	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	10.2	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.7	2.9	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.6	7.5	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6	1.8	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.5	1.6	GO:0051311	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.5	2.6	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.5	2.5	GO:0048539	bone marrow development(GO:0048539)
0.4	1.8	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.4	1.2	GO:0072709	cellular response to sorbitol(GO:0072709)
0.4	1.4	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.3	1.0	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.3	1.0	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.3	0.9	GO:0071284	cellular response to lead ion(GO:0071284)
0.3	0.8	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.3	0.8	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.3	2.1	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3	1.0	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2	0.7	GO:0051697	protein delipidation(GO:0051697)
0.2	1.2	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2	0.9	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	2.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2	1.5	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.2	2.0	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.2	0.7	GO:0071461	cellular response to redox state(GO:0071461)
0.2	0.5	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.2	0.7	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.2	0.8	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2	0.5	GO:0009183	purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) dGDP metabolic process(GO:0046066)
0.1	0.4	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.1	1.0	GO:0032594	protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.1	0.7	GO:0015722	canalicular bile acid transport(GO:0015722)
0.1	0.6	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	1.6	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	0.4	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.1	0.8	GO:1903960	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.1	0.4	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.1	1.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	0.4	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	0.6	GO:0006574	valine catabolic process(GO:0006574)
0.1	1.3	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.1	0.6	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	0.4	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.1	0.8	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.1	0.5	GO:1900533	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1	1.2	GO:0042262	DNA protection(GO:0042262)
0.1	0.7	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.5	GO:0000103	sulfate assimilation(GO:0000103)
0.1	1.7	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.5	GO:0072166	posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1	0.1	GO:1903056	regulation of melanosome organization(GO:1903056)
0.1	0.3	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.1	0.8	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.5	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	0.3	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	0.3	GO:0014016	neuroblast differentiation(GO:0014016)
0.1	15.5	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.6	GO:0051661	maintenance of centrosome location(GO:0051661)
0.1	0.3	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
0.1	0.6	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	2.4	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	0.7	GO:0044245	polysaccharide digestion(GO:0044245)
0.1	3.6	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.1	0.3	GO:1901253	negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.1	0.3	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.1	1.2	GO:0070986	left/right axis specification(GO:0070986)
0.1	0.4	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	0.4	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.1	0.9	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.4	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1	0.6	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	0.4	GO:0060406	positive regulation of penile erection(GO:0060406)
0.1	0.4	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.1	1.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	1.1	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.1	0.5	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.1	0.6	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	0.3	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1	0.3	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	0.5	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.1	0.2	GO:0035377	transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1	0.9	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.4	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	1.1	GO:0015671	oxygen transport(GO:0015671)
0.1	0.2	GO:1903487	regulation of lactation(GO:1903487)
0.1	0.1	GO:1905064	negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1	0.2	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.1	0.5	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.1	5.0	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.2	GO:0030910	olfactory placode formation(GO:0030910) myotome development(GO:0061055) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	2.9	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	1.5	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.2	GO:1903676	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1	1.1	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.7	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.1	0.4	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	0.3	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.4	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.1	0.6	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.1	0.3	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.1	1.7	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1	0.4	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	1.0	GO:0006312	mitotic recombination(GO:0006312)
0.1	0.4	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.3	GO:0072143	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1	0.1	GO:0070301	response to hydrogen peroxide(GO:0042542) cellular response to hydrogen peroxide(GO:0070301)
0.1	2.7	GO:0070206	protein trimerization(GO:0070206)
0.1	0.6	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	0.3	GO:1901096	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1	0.3	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.1	GO:0001810	regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.1	1.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	2.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	2.8	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	0.3	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.3	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.0	0.4	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.2	GO:0061355	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) negative regulation of Wnt protein secretion(GO:0061358)
0.0	0.2	GO:0071874	response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0	0.3	GO:0006226	dUMP biosynthetic process(GO:0006226) dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.0	0.4	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.0	1.2	GO:0006825	copper ion transport(GO:0006825)
0.0	0.9	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.3	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.2	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.4	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.2	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.4	GO:0051095	regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0	0.6	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	1.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:1903179	detoxification of mercury ion(GO:0050787) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.0	0.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	1.1	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
0.0	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.2	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.0	1.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.3	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.7	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.4	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.1	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0	0.1	GO:0060434	bronchus morphogenesis(GO:0060434)
0.0	0.2	GO:0097338	response to clozapine(GO:0097338)
0.0	0.2	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.0	0.7	GO:0045730	respiratory burst(GO:0045730)
0.0	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.8	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	1.5	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.9	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.3	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0	0.2	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.4	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:0071301	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0	0.1	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0	0.8	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.6	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.4	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0	0.4	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.3	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
0.0	0.8	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.4	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.2	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.2	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.2	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836) telomere assembly(GO:0032202)
0.0	0.1	GO:0035897	proteolysis in other organism(GO:0035897)
0.0	0.2	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.2	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.4	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.3	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	0.1	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.7	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.7	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.0	0.2	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0	0.9	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	1.0	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.5	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.2	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.1	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.1	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.0	0.3	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.3	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.6	GO:0030048	actin filament-based movement(GO:0030048)
0.0	1.1	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.4	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.6	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:2000143	negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.3	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.1	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.3	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.4	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.7	GO:0044247	polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	0.0	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.2	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.5	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.3	GO:0006265	DNA topological change(GO:0006265)
0.0	0.8	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	1.2	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.4	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	1.5	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.1	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	0.2	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.3	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.5	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.3	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0	0.2	GO:0014029	neural crest formation(GO:0014029)
0.0	0.0	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.0	0.4	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.7	GO:1901998	toxin transport(GO:1901998)
0.0	0.1	GO:0021784	postganglionic parasympathetic fiber development(GO:0021784)
0.0	0.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.0	GO:0070305	response to cGMP(GO:0070305)
0.0	0.1	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0	0.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.1	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.2	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.6	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.2	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.5	GO:0046039	GTP metabolic process(GO:0046039)
0.0	0.2	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.8	GO:1902403	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.3	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.3	GO:0097435	fibril organization(GO:0097435)
0.0	0.0	GO:0021997	response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:2001023	regulation of response to drug(GO:2001023)
0.0	0.5	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.5	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.2	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.2	GO:0007507	heart development(GO:0007507)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0002580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0	0.2	GO:0046606	negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.4	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.2	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.1	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.3	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.3	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.1	GO:0034334	adherens junction maintenance(GO:0034334)
0.0	0.4	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.2	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.4	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.0	0.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	1.1	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.7	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.4	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.2	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:1902415	regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416) regulation of RNA binding(GO:1905214) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.1	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.0	0.1	GO:0035855	secretory granule organization(GO:0033363) megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	10.2	GO:0044326	dendritic spine neck(GO:0044326)
0.9	12.4	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5	1.6	GO:0005715	late recombination nodule(GO:0005715)
0.4	1.8	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.3	1.0	GO:0018444	translation release factor complex(GO:0018444)
0.3	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.3	2.1	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	1.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3	1.8	GO:0030870	Mre11 complex(GO:0030870)
0.2	1.0	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.1	1.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	7.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	1.0	GO:0030061	mitochondrial crista(GO:0030061)
0.1	2.4	GO:0001726	ruffle(GO:0001726)
0.1	2.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.4	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	0.3	GO:0032437	cuticular plate(GO:0032437)
0.1	0.5	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	3.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.6	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	1.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.6	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	1.0	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	0.4	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1	0.7	GO:0032010	phagolysosome(GO:0032010)
0.1	0.2	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1	0.6	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.5	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1	0.3	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	1.1	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.5	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.3	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.1	0.5	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.2	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.1	0.4	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	0.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.4	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.4	GO:0005927	muscle tendon junction(GO:0005927)
0.1	0.3	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	1.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	1.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	1.0	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	1.6	GO:0030990	intraciliary transport particle(GO:0030990)
0.1	0.7	GO:0042555	MCM complex(GO:0042555)
0.1	0.9	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	3.3	GO:0015030	Cajal body(GO:0015030)
0.1	0.6	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.4	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0	0.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.2	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.0	2.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0061617	MICOS complex(GO:0061617)
0.0	0.4	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.3	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.0	1.1	GO:0032420	stereocilium(GO:0032420)
0.0	1.3	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	1.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.6	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0097449	astrocyte projection(GO:0097449) growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.0	0.1	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.7	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	1.7	GO:0000786	nucleosome(GO:0000786)
0.0	0.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	1.5	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.5	GO:0034709	methylosome(GO:0034709)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.7	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	1.9	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.4	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.3	GO:0030175	filopodium(GO:0030175) actin-based cell projection(GO:0098858)
0.0	0.1	GO:0016235	aggresome(GO:0016235)
0.0	0.9	GO:0072562	blood microparticle(GO:0072562)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.4	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.3	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.1	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.3	GO:0033010	paranodal junction(GO:0033010)
0.0	0.4	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.2	GO:0014802	terminal cisterna(GO:0014802)
0.0	0.2	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.4	GO:0005605	basal lamina(GO:0005605)
0.0	0.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.0	GO:0005873	plus-end kinesin complex(GO:0005873)
0.0	0.4	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.1	GO:0097224	sperm connecting piece(GO:0097224)
0.0	0.5	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.5	GO:0005921	gap junction(GO:0005921)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.3	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.0	GO:0097679	other organism cytoplasm(GO:0097679)
0.0	0.4	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.1	GO:0033063	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	6.8	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.9	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0	0.3	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.9	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	2.0	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	1.2	GO:0005856	cytoskeleton(GO:0005856)
0.0	0.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.4	GO:0008180	COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4	1.3	GO:0015616	DNA translocase activity(GO:0015616)
0.3	2.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3	1.0	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.3	0.3	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.3	1.8	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.3	1.5	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.3	0.9	GO:0032767	copper-dependent protein binding(GO:0032767)
0.3	0.8	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.3	10.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3	1.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	1.0	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2	0.9	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2	0.7	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.2	1.6	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.2	1.2	GO:0005499	vitamin D binding(GO:0005499)
0.2	2.2	GO:1990459	transferrin receptor binding(GO:1990459)
0.2	1.4	GO:0016778	diphosphotransferase activity(GO:0016778)
0.2	0.7	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.2	0.7	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2	0.8	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.2	0.5	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2	1.0	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2	1.3	GO:0001849	complement component C1q binding(GO:0001849)
0.2	0.8	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2	0.5	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1	0.6	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.4	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.1	0.6	GO:0015265	glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.1	0.4	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1	7.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	0.4	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.1	0.6	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	1.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.4	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1	0.4	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	2.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.7	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	8.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.5	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	3.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.4	GO:0008431	vitamin E binding(GO:0008431)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.4	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1	0.3	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.3	GO:0002113	interleukin-33 binding(GO:0002113)
0.1	1.2	GO:0089720	caspase binding(GO:0089720)
0.1	1.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	2.5	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.3	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	0.5	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	0.4	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	1.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0004132	dCMP deaminase activity(GO:0004132)
0.1	0.4	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.1	0.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	0.3	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.1	0.2	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.1	1.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	1.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	1.2	GO:0070513	death domain binding(GO:0070513)
0.1	4.2	GO:0070888	E-box binding(GO:0070888)
0.1	0.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.7	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.6	GO:0015266	protein channel activity(GO:0015266)
0.1	1.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	2.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	8.9	GO:0003823	antigen binding(GO:0003823)
0.1	0.6	GO:0033038	bitter taste receptor activity(GO:0033038)
0.1	0.2	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	0.3	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.4	GO:0004064	arylesterase activity(GO:0004064)
0.0	2.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.3	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0035276	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.0	1.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	2.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	1.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.9	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0004979	beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0	0.2	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	0.6	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.2	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0017130	poly(C) RNA binding(GO:0017130)
0.0	0.1	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0	0.3	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	1.0	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.0	0.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0	0.1	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0	0.3	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.5	GO:0001968	fibronectin binding(GO:0001968)
0.0	1.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.7	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0001861	complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.0	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	1.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.1	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.5	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0001851	complement component C3b binding(GO:0001851)
0.0	0.8	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.6	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.3	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.5	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.1	GO:0019960	C-X3-C chemokine receptor activity(GO:0016495) C-X3-C chemokine binding(GO:0019960)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.4	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0	1.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.3	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.3	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.6	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.2	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0	0.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.6	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.2	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.6	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	1.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	1.0	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.4	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.0	0.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.5	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.1	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.0	0.1	GO:0043142	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.4	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.2	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.4	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.4	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.3	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.2	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.0	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	1.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.2	GO:0032183	SUMO binding(GO:0032183)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.4	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	2.0	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	1.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	0.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0035240	dopamine binding(GO:0035240)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.5	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	0.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.2	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.2	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.0	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	5.2	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	0.8	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	2.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	2.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	0.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	2.7	PID BARD1 PATHWAY	BARD1 signaling events
0.1	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	2.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	2.9	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.6	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	1.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.9	PID E2F PATHWAY	E2F transcription factor network
0.0	1.5	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.8	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.6	PID SHP2 PATHWAY	SHP2 signaling
0.0	2.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway

Results for SHOX2_HOXC5

Z-value: 1.20

Motif logo

Transcription factors associated with SHOX2_HOXC5

Activity-expression correlation:

Activity profile of SHOX2_HOXC5 motif

Sorted Z-values of SHOX2_HOXC5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SHOX2_HOXC5

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category: