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ENCODE cell lines, expression (Ernst 2011)

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Results for SMAD2

Z-value: 0.79

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Transcription factors associated with SMAD2

Gene Symbol Gene ID Gene Info
SMAD2
ENSG00000175387.11 SMAD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD2hg19_v2_chr18_-_45457192_454572780.401.3e-01Click!

Activity profile of SMAD2 motif

Sorted Z-values of SMAD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_7297519 1.25 ENST00000576362.1
ENST00000571078.1
 TMEM256-PLSCR3
 TMEM256-PLSCR3 readthrough (NMD candidate)
chr17_-_15165854 1.23 ENST00000395936.1
ENST00000395938.2
 PMP22
 peripheral myelin protein 22
chr12_-_47473557 1.11 ENST00000321382.3
 AMIGO2
 adhesion molecule with Ig-like domain 2
chr11_-_33913708 1.07 ENST00000257818.2
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr12_-_47473642 1.05 ENST00000266581.4
 AMIGO2
 adhesion molecule with Ig-like domain 2
chr17_-_7297833 1.03 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
 TMEM256-PLSCR3
 TMEM256-PLSCR3 readthrough (NMD candidate)
chr20_-_23066953 1.03 ENST00000246006.4
 CD93
 CD93 molecule
chr17_-_46623441 1.01 ENST00000330070.4
 HOXB2
 homeobox B2
chr12_-_47473425 1.01 ENST00000550413.1
 AMIGO2
 adhesion molecule with Ig-like domain 2
chrX_-_107018969 0.96 ENST00000372383.4
 TSC22D3
 TSC22 domain family, member 3
chr3_-_15374659 0.93 ENST00000426925.1
 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
chr3_+_150321068 0.91 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
 SELT
 Selenoprotein T
chr20_+_43343517 0.87 ENST00000372865.4
 WISP2
 WNT1 inducible signaling pathway protein 2
chr6_+_6588316 0.85 ENST00000379953.2
 LY86
 lymphocyte antigen 86
chr20_+_43343886 0.84 ENST00000190983.4
 WISP2
 WNT1 inducible signaling pathway protein 2
chr20_+_43343476 0.84 ENST00000372868.2
 WISP2
 WNT1 inducible signaling pathway protein 2
chr17_+_68165657 0.76 ENST00000243457.3
 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
chr12_+_93965451 0.74 ENST00000548537.1
 SOCS2
 suppressor of cytokine signaling 2
chr1_-_153508460 0.70 ENST00000462776.2
 S100A6
 S100 calcium binding protein A6
chr6_+_6588902 0.64 ENST00000230568.4
 LY86
 lymphocyte antigen 86
chr17_+_7792101 0.64 ENST00000358181.4
ENST00000330494.7
 CHD3
 chromodomain helicase DNA binding protein 3
chr16_+_31483374 0.62 ENST00000394863.3
 TGFB1I1
 transforming growth factor beta 1 induced transcript 1
chr2_+_5832799 0.58 ENST00000322002.3
 SOX11
 SRY (sex determining region Y)-box 11
chr12_+_93965609 0.57 ENST00000549887.1
ENST00000551556.1
 SOCS2
 suppressor of cytokine signaling 2
chr8_-_95907423 0.57 ENST00000396133.3
ENST00000308108.4
 CCNE2
 cyclin E2
chr3_+_9834179 0.55 ENST00000498623.2
 ARPC4
 actin related protein 2/3 complex, subunit 4, 20kDa
chr9_+_125137565 0.53 ENST00000373698.5
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_3571934 0.52 ENST00000225525.3
 TAX1BP3
 Tax1 (human T-cell leukemia virus type I) binding protein 3
chrX_-_107019181 0.52 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
 TSC22D3
 TSC22 domain family, member 3
chr1_+_100111479 0.52 ENST00000263174.4
 PALMD
 palmdelphin
chr3_+_52529346 0.51 ENST00000321725.6
 STAB1
 stabilin 1
chr5_-_150521192 0.50 ENST00000523714.1
ENST00000521749.1
 ANXA6
 annexin A6
chr1_+_100111580 0.50 ENST00000605497.1
 PALMD
 palmdelphin
chr11_-_108464465 0.49 ENST00000525344.1
 EXPH5
 exophilin 5
chr3_-_88108192 0.48 ENST00000309534.6
 CGGBP1
 CGG triplet repeat binding protein 1
chr22_+_24891210 0.48 ENST00000382760.2
 UPB1
 ureidopropionase, beta
chr3_-_88108212 0.48 ENST00000482016.1
 CGGBP1
 CGG triplet repeat binding protein 1
chr12_+_68042517 0.47 ENST00000393555.3
 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr6_-_152489484 0.47 ENST00000354674.4
ENST00000539504.1
 SYNE1
 spectrin repeat containing, nuclear envelope 1
chr10_-_14372870 0.46 ENST00000357447.2
 FRMD4A
 FERM domain containing 4A
chr6_+_99282570 0.46 ENST00000328345.5
 POU3F2
 POU class 3 homeobox 2
chr6_+_39760129 0.45 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr4_-_41216492 0.44 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
chr4_-_5890145 0.43 ENST00000397890.2
 CRMP1
 collapsin response mediator protein 1
chr4_-_41216473 0.42 ENST00000513140.1
 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
chr22_+_29876197 0.42 ENST00000310624.6
 NEFH
 neurofilament, heavy polypeptide
chr12_-_10251576 0.41 ENST00000315330.4
 CLEC1A
 C-type lectin domain family 1, member A
chr12_-_8765446 0.41 ENST00000537228.1
ENST00000229335.6
 AICDA
 activation-induced cytidine deaminase
chr16_-_17564738 0.40 ENST00000261381.6
 XYLT1
 xylosyltransferase I
chr13_+_114238997 0.40 ENST00000538138.1
ENST00000375370.5
 TFDP1
 transcription factor Dp-1
chr12_-_10251603 0.38 ENST00000457018.2
 CLEC1A
 C-type lectin domain family 1, member A
chr1_+_16693578 0.37 ENST00000401088.4
ENST00000471507.1
ENST00000401089.3
ENST00000375590.3
ENST00000492354.1
 SZRD1
 SUZ RNA binding domain containing 1
chr9_+_101867359 0.37 ENST00000374994.4
 TGFBR1
 transforming growth factor, beta receptor 1
chr1_-_211752073 0.36 ENST00000367001.4
 SLC30A1
 solute carrier family 30 (zinc transporter), member 1
chr8_+_82192501 0.35 ENST00000297258.6
 FABP5
 fatty acid binding protein 5 (psoriasis-associated)
chr6_+_39760783 0.34 ENST00000398904.2
ENST00000538976.1
 DAAM2
 dishevelled associated activator of morphogenesis 2
chr21_-_38639813 0.34 ENST00000309117.6
ENST00000398998.1
 DSCR3
 Down syndrome critical region gene 3
chr3_-_49761337 0.34 ENST00000535833.1
ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
 AMIGO3
GMPPB
 adhesion molecule with Ig-like domain 3
GDP-mannose pyrophosphorylase B
chr12_-_10251539 0.34 ENST00000420265.2
 CLEC1A
 C-type lectin domain family 1, member A
chr3_+_23847394 0.33 ENST00000306627.3
 UBE2E1
 ubiquitin-conjugating enzyme E2E 1
chr20_-_56284816 0.33 ENST00000395819.3
ENST00000341744.3
 PMEPA1
 prostate transmembrane protein, androgen induced 1
chr5_+_140762268 0.33 ENST00000518325.1
 PCDHGA7
 protocadherin gamma subfamily A, 7
chr9_+_34990219 0.33 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
 DNAJB5
 DnaJ (Hsp40) homolog, subfamily B, member 5
chr9_+_101867387 0.33 ENST00000374990.2
ENST00000552516.1
 TGFBR1
 transforming growth factor, beta receptor 1
chr6_+_143772060 0.31 ENST00000367591.4
 PEX3
 peroxisomal biogenesis factor 3
chr3_+_130569592 0.31 ENST00000533801.2
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr7_-_10979750 0.31 ENST00000339600.5
 NDUFA4
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr11_-_107729887 0.31 ENST00000525815.1
 SLC35F2
 solute carrier family 35, member F2
chr4_-_41216619 0.30 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
chr4_-_103749205 0.30 ENST00000508249.1
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr11_+_75273101 0.29 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
 SERPINH1
 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr3_+_130569429 0.29 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
 ATP2C1
 ATPase, Ca++ transporting, type 2C, member 1
chr11_-_107590383 0.28 ENST00000525934.1
ENST00000531293.1
 SLN
 sarcolipin
chr21_+_47401650 0.28 ENST00000361866.3
 COL6A1
 collagen, type VI, alpha 1
chr3_+_23847432 0.27 ENST00000346855.3
 UBE2E1
 ubiquitin-conjugating enzyme E2E 1
chr3_+_123813509 0.26 ENST00000460856.1
ENST00000240874.3
 KALRN
 kalirin, RhoGEF kinase
chr3_-_195163803 0.26 ENST00000326793.6
 ACAP2
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr17_-_46178741 0.26 ENST00000581003.1
ENST00000225603.4
 CBX1
 chromobox homolog 1
chr1_-_149783914 0.23 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
 HIST2H2BF
 histone cluster 2, H2bf
chr12_+_53443963 0.23 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr1_-_149908217 0.22 ENST00000369140.3
 MTMR11
 myotubularin related protein 11
chr4_-_164534657 0.22 ENST00000339875.5
 MARCH1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr12_-_56583243 0.22 ENST00000550164.1
 SMARCC2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr11_+_117857063 0.22 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
 IL10RA
 interleukin 10 receptor, alpha
chr11_-_101454658 0.22 ENST00000344327.3
 TRPC6
 transient receptor potential cation channel, subfamily C, member 6
chr19_-_43383819 0.22 ENST00000312439.6
ENST00000403380.3
 PSG1
 pregnancy specific beta-1-glycoprotein 1
chr11_-_3859089 0.21 ENST00000396979.1
 RHOG
 ras homolog family member G
chr12_+_67663056 0.21 ENST00000545606.1
 CAND1
 cullin-associated and neddylation-dissociated 1
chr4_-_39979576 0.21 ENST00000303538.8
ENST00000503396.1
 PDS5A
 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr12_+_68042495 0.21 ENST00000344096.3
 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr12_-_71003568 0.21 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr19_-_3606838 0.20 ENST00000375190.4
 TBXA2R
 thromboxane A2 receptor
chr2_+_113033164 0.20 ENST00000409871.1
ENST00000343936.4
 ZC3H6
 zinc finger CCCH-type containing 6
chr1_-_201915590 0.20 ENST00000367288.4
 LMOD1
 leiomodin 1 (smooth muscle)
chr12_-_120554534 0.19 ENST00000538903.1
ENST00000534951.1
 RAB35
 RAB35, member RAS oncogene family
chr11_+_71238313 0.19 ENST00000398536.4
 KRTAP5-7
 keratin associated protein 5-7
chr1_+_160085501 0.18 ENST00000361216.3
 ATP1A2
 ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr7_+_155250824 0.18 ENST00000297375.4
 EN2
 engrailed homeobox 2
chr12_-_104531785 0.18 ENST00000551727.1
 NFYB
 nuclear transcription factor Y, beta
chr19_-_44285401 0.17 ENST00000262888.3
 KCNN4
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr16_+_28889801 0.17 ENST00000395503.4
 ATP2A1
 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr7_-_102257139 0.16 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
 RASA4
 RAS p21 protein activator 4
chr4_-_103749179 0.16 ENST00000502690.1
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr16_+_28889703 0.16 ENST00000357084.3
 ATP2A1
 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr15_+_75498739 0.15 ENST00000565074.1
 C15orf39
 chromosome 15 open reading frame 39
chr12_+_122516626 0.15 ENST00000319080.7
 MLXIP
 MLX interacting protein
chr1_-_44482979 0.15 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr9_+_15422702 0.15 ENST00000380821.3
ENST00000421710.1
 SNAPC3
 small nuclear RNA activating complex, polypeptide 3, 50kDa
chr1_-_207119738 0.14 ENST00000356495.4
 PIGR
 polymeric immunoglobulin receptor
chr1_+_160097462 0.14 ENST00000447527.1
 ATP1A2
 ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_-_149908710 0.14 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
 MTMR11
 myotubularin related protein 11
chr22_-_24641027 0.14 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
 GGT5
 gamma-glutamyltransferase 5
chr22_+_22764088 0.13 ENST00000390299.2
 IGLV1-40
 immunoglobulin lambda variable 1-40
chr20_+_1875942 0.13 ENST00000358771.4
 SIRPA
 signal-regulatory protein alpha
chr22_+_31518938 0.13 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
 INPP5J
 inositol polyphosphate-5-phosphatase J
chr5_+_140345820 0.13 ENST00000289269.5
 PCDHAC2
 protocadherin alpha subfamily C, 2
chr6_+_30689401 0.13 ENST00000396389.1
ENST00000396384.1
 TUBB
 tubulin, beta class I
chr19_+_41594377 0.12 ENST00000330436.3
 CYP2A13
 cytochrome P450, family 2, subfamily A, polypeptide 13
chrX_+_153029633 0.12 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
 PLXNB3
 plexin B3
chr20_+_44098385 0.12 ENST00000217425.5
ENST00000339946.3
 WFDC2
 WAP four-disulfide core domain 2
chr12_-_3982511 0.12 ENST00000427057.2
ENST00000228820.4
 PARP11
 poly (ADP-ribose) polymerase family, member 11
chr19_-_11688447 0.11 ENST00000590420.1
 ACP5
 acid phosphatase 5, tartrate resistant
chr4_-_103749313 0.11 ENST00000394803.5
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr22_-_31885514 0.11 ENST00000397525.1
 EIF4ENIF1
 eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_-_49131013 0.10 ENST00000424300.1
 QRICH1
 glutamine-rich 1
chr12_+_53443680 0.10 ENST00000314250.6
ENST00000451358.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr2_+_27237615 0.10 ENST00000458529.1
ENST00000402218.1
 MAPRE3
 microtubule-associated protein, RP/EB family, member 3
chr19_-_42636543 0.10 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
 POU2F2
 POU class 2 homeobox 2
chr8_-_102217796 0.09 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
 ZNF706
 zinc finger protein 706
chr19_+_49128209 0.09 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
 SPHK2
 sphingosine kinase 2
chr5_+_133861339 0.09 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
 PHF15
 jade family PHD finger 2
chr11_-_46142948 0.09 ENST00000257821.4
 PHF21A
 PHD finger protein 21A
chr7_-_102158157 0.09 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
 RASA4B
 RAS p21 protein activator 4B
chr1_-_44497118 0.08 ENST00000537678.1
ENST00000466926.1
 SLC6A9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_-_14224969 0.08 ENST00000589994.1
 PRKACA
 protein kinase, cAMP-dependent, catalytic, alpha
chr20_+_44098346 0.08 ENST00000372676.3
 WFDC2
 WAP four-disulfide core domain 2
chr9_+_133569108 0.08 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
 EXOSC2
 exosome component 2
chr17_-_1389419 0.08 ENST00000575158.1
 MYO1C
 myosin IC
chr11_+_2923423 0.08 ENST00000312221.5
 SLC22A18
 solute carrier family 22, member 18
chr14_+_62162258 0.07 ENST00000337138.4
ENST00000394997.1
 HIF1A
 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr14_+_70078303 0.07 ENST00000342745.4
 KIAA0247
 KIAA0247
chr15_+_68570062 0.07 ENST00000306917.4
 FEM1B
 fem-1 homolog b (C. elegans)
chr10_+_105314881 0.07 ENST00000437579.1
 NEURL
 neuralized E3 ubiquitin protein ligase 1
chr4_-_99851766 0.06 ENST00000450253.2
 EIF4E
 eukaryotic translation initiation factor 4E
chr3_-_195603566 0.06 ENST00000424563.1
ENST00000411741.1
 TNK2
 tyrosine kinase, non-receptor, 2
chr7_-_105516923 0.06 ENST00000478915.1
 ATXN7L1
 ataxin 7-like 1
chr21_-_38338773 0.06 ENST00000399120.1
ENST00000419461.1
 HLCS
 holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr9_-_136006496 0.06 ENST00000372062.3
 RALGDS
 ral guanine nucleotide dissociation stimulator
chr12_-_57410304 0.05 ENST00000441881.1
ENST00000458521.2
 TAC3
 tachykinin 3
chr12_-_57472522 0.05 ENST00000379391.3
ENST00000300128.4
 TMEM194A
 transmembrane protein 194A
chr2_-_73053126 0.05 ENST00000272427.6
ENST00000410104.1
 EXOC6B
 exocyst complex component 6B
chr10_+_72972281 0.05 ENST00000335350.6
 UNC5B
 unc-5 homolog B (C. elegans)
chr19_-_46105411 0.04 ENST00000323040.4
ENST00000544371.1
 GPR4
OPA3
 G protein-coupled receptor 4
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr2_+_168725458 0.04 ENST00000392690.3
 B3GALT1
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr19_+_13106383 0.04 ENST00000397661.2
 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
chr7_+_107384579 0.04 ENST00000222597.2
ENST00000415884.2
 CBLL1
 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chrX_-_47489244 0.04 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
 CFP
 complement factor properdin
chr16_+_53164833 0.04 ENST00000564845.1
 CHD9
 chromodomain helicase DNA binding protein 9
chr19_-_42636617 0.04 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
 POU2F2
 POU class 2 homeobox 2
chr16_-_67997947 0.04 ENST00000537830.2
 SLC12A4
 solute carrier family 12 (potassium/chloride transporter), member 4
chr12_-_89918522 0.04 ENST00000529983.2
 GALNT4
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr1_+_156163880 0.04 ENST00000359511.4
ENST00000423538.2
 SLC25A44
 solute carrier family 25, member 44
chr11_-_34535297 0.04 ENST00000532417.1
 ELF5
 E74-like factor 5 (ets domain transcription factor)
chr2_-_72375167 0.03 ENST00000001146.2
 CYP26B1
 cytochrome P450, family 26, subfamily B, polypeptide 1
chr22_+_22676808 0.03 ENST00000390290.2
 IGLV1-51
 immunoglobulin lambda variable 1-51
chr19_-_54824344 0.03 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
 LILRA5
 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr1_+_2407754 0.03 ENST00000419816.2
ENST00000378486.3
ENST00000378488.3
ENST00000288766.5
 PLCH2
 phospholipase C, eta 2
chr22_-_38851205 0.03 ENST00000303592.3
 KCNJ4
 potassium inwardly-rectifying channel, subfamily J, member 4
chr15_-_88799384 0.02 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
 NTRK3
 neurotrophic tyrosine kinase, receptor, type 3
chr5_-_64064508 0.02 ENST00000513458.4
 SREK1IP1
 SREK1-interacting protein 1
chr1_+_174933899 0.02 ENST00000367688.3
 RABGAP1L
 RAB GTPase activating protein 1-like
chr1_+_159141397 0.02 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
 CADM3
 cell adhesion molecule 3
chr8_+_94241867 0.02 ENST00000598428.1
 AC016885.1
 Uncharacterized protein
chr4_-_103748880 0.02 ENST00000453744.2
ENST00000349311.8
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr19_-_6481776 0.02 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
 DENND1C
 DENN/MADD domain containing 1C
chr19_-_14606900 0.02 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
 GIPC1
 GIPC PDZ domain containing family, member 1
chr3_-_150320937 0.02 ENST00000479209.1
 SERP1
 stress-associated endoplasmic reticulum protein 1
chr19_-_18337240 0.01 ENST00000262805.12
 PDE4C
 phosphodiesterase 4C, cAMP-specific
chr22_+_22735135 0.01 ENST00000390297.2
 IGLV1-44
 immunoglobulin lambda variable 1-44
chr14_-_106478603 0.01 ENST00000390596.2
 IGHV4-4
 immunoglobulin heavy variable 4-4
chr4_-_103749105 0.01 ENST00000394801.4
ENST00000394804.2
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chrX_-_30595959 0.01 ENST00000378962.3
 CXorf21
 chromosome X open reading frame 21
chr16_-_425205 0.01 ENST00000448854.1
 TMEM8A
 transmembrane protein 8A
chr15_-_88799661 0.01 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
 NTRK3
 neurotrophic tyrosine kinase, receptor, type 3
chr13_+_25670268 0.01 ENST00000281589.3
 PABPC3
 poly(A) binding protein, cytoplasmic 3
chr1_-_160040038 0.01 ENST00000368089.3
 KCNJ10
 potassium inwardly-rectifying channel, subfamily J, member 10
chr1_-_94586651 0.00 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr19_+_11466167 0.00 ENST00000591608.1
 DKFZP761J1410
 Lipid phosphate phosphatase-related protein type 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 1.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 1.5 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.7 GO:1905073 proepicardium development(GO:0003342) septum transversum development(GO:0003343) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.2 1.5 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 0.5 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.4 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.4 GO:0048936 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.6 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.3 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.3 GO:0051941 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 3.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 1.1 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.0 0.3 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.5 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0070781 response to biotin(GO:0070781)
0.0 0.5 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.6 GO:0007129 synapsis(GO:0007129)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322) saliva secretion(GO:0046541)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.0 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 1.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.8 GO:0005768 endosome(GO:0005768)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.2 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 2.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.8 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0036374 glutathione hydrolase activity(GO:0036374)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters