ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SOX10 Links Ensembl NCBI GeneCards UniProt	ENSG00000100146.12	SOX10
SOX15 Links Ensembl NCBI GeneCards UniProt	ENSG00000129194.3	SOX15

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SOX15	hg19_v2_chr17_-_7493390_7493488	-0.53	3.5e-02	Click!
SOX10	hg19_v2_chr22_-_38380543_38380569	0.47	6.9e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr1_-_32801825	4.31	ENST00000329421.7	MARCKSL1	MARCKS-like 1
chr8_-_80993010	3.27	ENST00000537855.1 ENST00000520527.1 ENST00000517427.1 ENST00000448733.2 ENST00000379097.3	TPD52	tumor protein D52
chr4_+_154387480	3.26	ENST00000409663.3 ENST00000440693.1 ENST00000409959.3	KIAA0922	KIAA0922
chr7_+_116660246	2.97	ENST00000434836.1 ENST00000393443.1 ENST00000465133.1 ENST00000477742.1 ENST00000393447.4 ENST00000393444.3	ST7	suppression of tumorigenicity 7
chr1_+_200993071	2.88	ENST00000446333.1 ENST00000458003.1	RP11-168O16.1	RP11-168O16.1
chr13_-_41593425	2.72	ENST00000239882.3	ELF1	E74-like factor 1 (ets domain transcription factor)
chr14_-_91884150	2.64	ENST00000553403.1	CCDC88C	coiled-coil domain containing 88C
chr1_-_200992827	2.43	ENST00000332129.2 ENST00000422435.2	KIF21B	kinesin family member 21B
chr17_+_36861735	2.34	ENST00000378137.5 ENST00000325718.7	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_+_133118839	2.32	ENST00000302334.2	BFSP2	beaded filament structural protein 2, phakinin
chr11_+_128563652	2.27	ENST00000527786.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr13_-_99959641	2.12	ENST00000376414.4	GPR183	G protein-coupled receptor 183
chr4_-_109090106	2.08	ENST00000379951.2	LEF1	lymphoid enhancer-binding factor 1
chr5_-_175964366	2.07	ENST00000274811.4	RNF44	ring finger protein 44
chr1_+_11751748	2.01	ENST00000294485.5	DRAXIN	dorsal inhibitory axon guidance protein
chr20_+_60718785	1.94	ENST00000421564.1 ENST00000450482.1 ENST00000331758.3	SS18L1	synovial sarcoma translocation gene on chromosome 18-like 1
chr6_-_29527702	1.90	ENST00000377050.4	UBD	ubiquitin D
chr18_-_74207146	1.72	ENST00000443185.2	ZNF516	zinc finger protein 516
chr20_-_45985172	1.64	ENST00000536340.1	ZMYND8	zinc finger, MYND-type containing 8
chr13_+_111767650	1.63	ENST00000449979.1 ENST00000370623.3	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr3_-_141747950	1.56	ENST00000497579.1	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_151431909	1.56	ENST00000361398.3 ENST00000271715.2	POGZ	pogo transposable element with ZNF domain
chr3_+_151986709	1.55	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1	muscleblind-like splicing regulator 1
chr11_+_125496619	1.53	ENST00000532669.1 ENST00000278916.3	CHEK1	checkpoint kinase 1
chr10_+_11206925	1.50	ENST00000354440.2 ENST00000315874.4 ENST00000427450.1	CELF2	CUGBP, Elav-like family member 2
chr20_-_4804244	1.42	ENST00000379400.3	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr1_+_192544857	1.38	ENST00000367459.3 ENST00000469578.2	RGS1	regulator of G-protein signaling 1
chr2_+_232573208	1.34	ENST00000409115.3	PTMA	prothymosin, alpha
chrX_+_129305623	1.34	ENST00000257017.4	RAB33A	RAB33A, member RAS oncogene family
chr2_+_70056762	1.32	ENST00000282570.3	GMCL1	germ cell-less, spermatogenesis associated 1
chr3_-_124839648	1.29	ENST00000430155.2	SLC12A8	solute carrier family 12, member 8
chr14_-_65409502	1.28	ENST00000389614.5	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr9_-_130712995	1.27	ENST00000373084.4	FAM102A	family with sequence similarity 102, member A
chr10_+_35484793	1.26	ENST00000488741.1 ENST00000474931.1 ENST00000468236.1 ENST00000344351.5 ENST00000490511.1	CREM	cAMP responsive element modulator
chr15_-_70388943	1.24	ENST00000559048.1 ENST00000560939.1 ENST00000440567.3 ENST00000557907.1 ENST00000558379.1 ENST00000451782.2 ENST00000559929.1	TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr7_+_29234028	1.22	ENST00000222792.6	CHN2	chimerin 2
chr6_+_119215308	1.17	ENST00000229595.5	ASF1A	anti-silencing function 1A histone chaperone
chr2_+_232573222	1.14	ENST00000341369.7 ENST00000409683.1	PTMA	prothymosin, alpha
chr18_+_72201829	1.11	ENST00000582365.1	CNDP1	carnosine dipeptidase 1 (metallopeptidase M20 family)
chr4_-_109089573	1.11	ENST00000265165.1	LEF1	lymphoid enhancer-binding factor 1
chr18_-_74728998	1.10	ENST00000359645.3 ENST00000397875.3 ENST00000397869.3 ENST00000578193.1 ENST00000578873.1 ENST00000397866.4 ENST00000528160.1 ENST00000527041.1 ENST00000526111.1 ENST00000397865.5 ENST00000382582.3	MBP	myelin basic protein
chr2_+_32288725	1.09	ENST00000315285.3	SPAST	spastin
chr8_+_21777159	1.08	ENST00000434536.1 ENST00000252512.9	XPO7	exportin 7
chr9_+_137218362	1.06	ENST00000481739.1	RXRA	retinoid X receptor, alpha
chr3_-_148939835	1.05	ENST00000264613.6	CP	ceruloplasmin (ferroxidase)
chr14_-_65409438	1.04	ENST00000557049.1	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr7_+_23146271	1.03	ENST00000545771.1	KLHL7	kelch-like family member 7
chr16_+_71660079	1.00	ENST00000565261.1 ENST00000268485.3 ENST00000299952.4	MARVELD3	MARVEL domain containing 3
chr2_+_27070964	0.96	ENST00000288699.6	DPYSL5	dihydropyrimidinase-like 5
chr14_-_51027838	0.94	ENST00000555216.1	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5
chr17_+_67498538	0.94	ENST00000589647.1	MAP2K6	mitogen-activated protein kinase kinase 6
chr6_+_122720681	0.93	ENST00000368455.4 ENST00000452194.1	HSF2	heat shock transcription factor 2
chr20_-_45984401	0.92	ENST00000311275.7	ZMYND8	zinc finger, MYND-type containing 8
chr4_+_74301880	0.92	ENST00000395792.2 ENST00000226359.2	AFP	alpha-fetoprotein
chr17_+_27071002	0.90	ENST00000262395.5 ENST00000422344.1 ENST00000444415.3 ENST00000262396.6	TRAF4	TNF receptor-associated factor 4
chr2_+_32288657	0.89	ENST00000345662.1	SPAST	spastin
chrX_+_37639264	0.88	ENST00000378588.4	CYBB	cytochrome b-245, beta polypeptide
chr3_+_111260954	0.86	ENST00000283285.5	CD96	CD96 molecule
chr14_-_35344093	0.85	ENST00000382422.2	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr14_-_71107921	0.83	ENST00000553982.1 ENST00000500016.1	CTD-2540L5.5 CTD-2540L5.6	CTD-2540L5.5 CTD-2540L5.6
chr12_-_42631529	0.82	ENST00000548917.1	YAF2	YY1 associated factor 2
chrX_+_70503433	0.81	ENST00000276079.8 ENST00000373856.3 ENST00000373841.1 ENST00000420903.1	NONO	non-POU domain containing, octamer-binding
chr7_+_29234101	0.79	ENST00000435288.2	CHN2	chimerin 2
chr2_+_120517174	0.79	ENST00000263708.2	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr15_+_75074410	0.78	ENST00000439220.2	CSK	c-src tyrosine kinase
chr2_+_89184868	0.77	ENST00000390243.2	IGKV4-1	immunoglobulin kappa variable 4-1
chr12_-_102874416	0.76	ENST00000392904.1 ENST00000337514.6	IGF1	insulin-like growth factor 1 (somatomedin C)
chr4_-_186877502	0.75	ENST00000431902.1 ENST00000284776.7 ENST00000415274.1	SORBS2	sorbin and SH3 domain containing 2
chr7_+_111846643	0.75	ENST00000361822.3	ZNF277	zinc finger protein 277
chr2_-_39348137	0.75	ENST00000426016.1	SOS1	son of sevenless homolog 1 (Drosophila)
chr6_+_64282447	0.74	ENST00000370650.2 ENST00000578299.1	PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr8_-_8751068	0.74	ENST00000276282.6	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr15_-_50647274	0.74	ENST00000543881.1	GABPB1	GA binding protein transcription factor, beta subunit 1
chr11_+_67007518	0.73	ENST00000530342.1 ENST00000308783.5	KDM2A	lysine (K)-specific demethylase 2A
chr5_-_65017921	0.72	ENST00000381007.4	SGTB	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr12_-_102874378	0.72	ENST00000456098.1	IGF1	insulin-like growth factor 1 (somatomedin C)
chr18_+_6729698	0.71	ENST00000383472.4	ARHGAP28	Rho GTPase activating protein 28
chr1_+_183774240	0.70	ENST00000360851.3	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr11_+_63706444	0.70	ENST00000377793.4 ENST00000456907.2 ENST00000539656.1	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr12_-_102872317	0.70	ENST00000424202.2	IGF1	insulin-like growth factor 1 (somatomedin C)
chrX_+_37639302	0.69	ENST00000545017.1 ENST00000536160.1	CYBB	cytochrome b-245, beta polypeptide
chr7_+_50344289	0.69	ENST00000413698.1 ENST00000359197.5 ENST00000331340.3 ENST00000357364.4 ENST00000343574.5 ENST00000349824.4 ENST00000346667.4 ENST00000440768.2	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr3_+_173116225	0.69	ENST00000457714.1	NLGN1	neuroligin 1
chr4_+_113152881	0.68	ENST00000274000.5	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr7_+_20370746	0.68	ENST00000222573.4	ITGB8	integrin, beta 8
chr20_+_61448376	0.67	ENST00000343916.3	COL9A3	collagen, type IX, alpha 3
chrX_-_32173579	0.67	ENST00000359836.1 ENST00000343523.2 ENST00000378707.3 ENST00000541735.1 ENST00000474231.1	DMD	dystrophin
chr6_-_64029879	0.67	ENST00000370658.5 ENST00000485906.2 ENST00000370657.4	LGSN	lengsin, lens protein with glutamine synthetase domain
chr8_+_81397876	0.65	ENST00000430430.1	ZBTB10	zinc finger and BTB domain containing 10
chrX_-_110655306	0.65	ENST00000371993.2	DCX	doublecortin
chr15_-_50647370	0.65	ENST00000558970.1 ENST00000396464.3 ENST00000560825.1	GABPB1	GA binding protein transcription factor, beta subunit 1
chr13_+_111365602	0.64	ENST00000333219.7	ING1	inhibitor of growth family, member 1
chr20_-_30795511	0.63	ENST00000246229.4	PLAGL2	pleiomorphic adenoma gene-like 2
chr16_-_73082274	0.62	ENST00000268489.5	ZFHX3	zinc finger homeobox 3
chr8_+_107738240	0.62	ENST00000449762.2 ENST00000297447.6	OXR1	oxidation resistance 1
chr3_-_167813132	0.61	ENST00000309027.4	GOLIM4	golgi integral membrane protein 4
chr20_+_48884002	0.61	ENST00000425497.1 ENST00000445003.1	RP11-290F20.3	RP11-290F20.3
chr4_+_113152978	0.61	ENST00000309703.6	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr17_+_75447326	0.61	ENST00000591088.1	SEPT9	septin 9
chr8_+_81398444	0.60	ENST00000455036.3 ENST00000426744.2	ZBTB10	zinc finger and BTB domain containing 10
chr2_+_10262857	0.59	ENST00000304567.5	RRM2	ribonucleotide reductase M2
chr1_-_151431647	0.59	ENST00000368863.2 ENST00000409503.1 ENST00000491586.1 ENST00000533351.1 ENST00000540984.1	POGZ	pogo transposable element with ZNF domain
chr7_-_22233442	0.58	ENST00000401957.2	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr1_-_114355083	0.58	ENST00000261441.5	RSBN1	round spermatid basic protein 1
chr6_+_87865262	0.57	ENST00000369577.3 ENST00000518845.1 ENST00000339907.4 ENST00000496806.2	ZNF292	zinc finger protein 292
chr8_-_70745575	0.56	ENST00000524945.1	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chr6_-_27114577	0.56	ENST00000356950.1 ENST00000396891.4	HIST1H2BK	histone cluster 1, H2bk
chr7_-_148581251	0.56	ENST00000478654.1 ENST00000460911.1 ENST00000350995.2	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr1_+_66458072	0.56	ENST00000423207.2	PDE4B	phosphodiesterase 4B, cAMP-specific
chr12_-_12419703	0.55	ENST00000543091.1 ENST00000261349.4	LRP6	low density lipoprotein receptor-related protein 6
chr1_+_244998602	0.55	ENST00000411948.2	COX20	COX20 cytochrome C oxidase assembly factor
chr15_+_57210961	0.54	ENST00000557843.1	TCF12	transcription factor 12
chr6_+_72596604	0.53	ENST00000348717.5 ENST00000517960.1 ENST00000518273.1 ENST00000522291.1 ENST00000521978.1 ENST00000520567.1 ENST00000264839.7	RIMS1	regulating synaptic membrane exocytosis 1
chr17_+_64961026	0.53	ENST00000262138.3	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr11_-_6677018	0.52	ENST00000299441.3	DCHS1	dachsous cadherin-related 1
chr2_-_152955537	0.51	ENST00000201943.5 ENST00000539935.1	CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr7_-_99679324	0.51	ENST00000292393.5 ENST00000413658.2 ENST00000412947.1 ENST00000441298.1 ENST00000449785.1 ENST00000299667.4 ENST00000424697.1	ZNF3	zinc finger protein 3
chr7_-_140178726	0.51	ENST00000480552.1	MKRN1	makorin ring finger protein 1
chr12_-_102874102	0.50	ENST00000392905.2	IGF1	insulin-like growth factor 1 (somatomedin C)
chr3_+_39509163	0.50	ENST00000436143.2 ENST00000441980.2 ENST00000311042.6	MOBP	myelin-associated oligodendrocyte basic protein
chr6_+_108881012	0.50	ENST00000343882.6	FOXO3	forkhead box O3
chrX_-_110655391	0.50	ENST00000356915.2 ENST00000356220.3	DCX	doublecortin
chr17_-_76713100	0.50	ENST00000585509.1	CYTH1	cytohesin 1
chr1_-_46152174	0.49	ENST00000290795.3 ENST00000355105.3	GPBP1L1	GC-rich promoter binding protein 1-like 1
chr7_+_44788430	0.49	ENST00000457123.1 ENST00000309315.4	ZMIZ2	zinc finger, MIZ-type containing 2
chr17_-_73389737	0.48	ENST00000392563.1	GRB2	growth factor receptor-bound protein 2
chr10_+_35415978	0.48	ENST00000429130.3 ENST00000469949.2 ENST00000460270.1	CREM	cAMP responsive element modulator
chr3_-_65583561	0.48	ENST00000460329.2	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chr11_-_102323489	0.47	ENST00000361236.3	TMEM123	transmembrane protein 123
chr11_-_102323740	0.47	ENST00000398136.2	TMEM123	transmembrane protein 123
chr4_+_76649797	0.47	ENST00000538159.1 ENST00000514213.2	USO1	USO1 vesicle transport factor
chr15_-_50647347	0.46	ENST00000220429.8 ENST00000429662.2	GABPB1	GA binding protein transcription factor, beta subunit 1
chr2_+_162272605	0.46	ENST00000389554.3	TBR1	T-box, brain, 1
chr5_+_43603229	0.46	ENST00000344920.4 ENST00000512996.2	NNT	nicotinamide nucleotide transhydrogenase
chrX_-_135962876	0.45	ENST00000431446.3 ENST00000570135.1 ENST00000320676.7 ENST00000562646.1	RBMX	RNA binding motif protein, X-linked
chr2_-_10588630	0.45	ENST00000234111.4	ODC1	ornithine decarboxylase 1
chr5_-_115910091	0.45	ENST00000257414.8	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_+_104359641	0.45	ENST00000537100.1	TDG	thymine-DNA glycosylase
chr12_+_15475462	0.45	ENST00000543886.1 ENST00000348962.2	PTPRO	protein tyrosine phosphatase, receptor type, O
chr17_-_79881408	0.44	ENST00000392366.3	MAFG	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr10_+_35415719	0.44	ENST00000474362.1 ENST00000374721.3	CREM	cAMP responsive element modulator
chr14_-_31495569	0.44	ENST00000357479.5 ENST00000355683.5	STRN3	striatin, calmodulin binding protein 3
chr6_+_114178512	0.44	ENST00000368635.4	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr12_-_109027643	0.43	ENST00000388962.3 ENST00000550948.1	SELPLG	selectin P ligand
chr1_-_234614849	0.43	ENST00000040877.1	TARBP1	TAR (HIV-1) RNA binding protein 1
chr5_+_43602750	0.43	ENST00000505678.2 ENST00000512422.1 ENST00000264663.5	NNT	nicotinamide nucleotide transhydrogenase
chr3_+_39509070	0.43	ENST00000354668.4 ENST00000428261.1 ENST00000420739.1 ENST00000415443.1 ENST00000447324.1 ENST00000383754.3	MOBP	myelin-associated oligodendrocyte basic protein
chr12_-_102874330	0.43	ENST00000307046.8	IGF1	insulin-like growth factor 1 (somatomedin C)
chr19_-_18717627	0.42	ENST00000392386.3	CRLF1	cytokine receptor-like factor 1
chr16_-_4852915	0.42	ENST00000322048.7	ROGDI	rogdi homolog (Drosophila)
chr17_+_7590734	0.42	ENST00000457584.2	WRAP53	WD repeat containing, antisense to TP53
chr7_+_87563557	0.42	ENST00000439864.1 ENST00000412441.1 ENST00000398201.4 ENST00000265727.7 ENST00000315984.7 ENST00000398209.3	ADAM22	ADAM metallopeptidase domain 22
chr11_+_46402744	0.41	ENST00000533952.1	MDK	midkine (neurite growth-promoting factor 2)
chr20_-_23066953	0.41	ENST00000246006.4	CD93	CD93 molecule
chr5_-_115872142	0.41	ENST00000510263.1	SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr15_+_92937144	0.40	ENST00000539113.1 ENST00000555434.1	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr11_+_46402583	0.40	ENST00000359803.3	MDK	midkine (neurite growth-promoting factor 2)
chr4_+_118955500	0.40	ENST00000296499.5	NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr15_+_92937058	0.40	ENST00000268164.3	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr3_-_46904946	0.40	ENST00000292327.4	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr15_+_52311398	0.40	ENST00000261845.5	MAPK6	mitogen-activated protein kinase 6
chr9_-_120177342	0.40	ENST00000361209.2	ASTN2	astrotactin 2
chr3_-_48470838	0.40	ENST00000358459.4 ENST00000358536.4	PLXNB1	plexin B1
chr12_-_102591604	0.40	ENST00000329406.4	PMCH	pro-melanin-concentrating hormone
chr12_+_124997766	0.40	ENST00000543970.1	RP11-83B20.1	RP11-83B20.1
chr2_+_169312725	0.39	ENST00000392687.4	CERS6	ceramide synthase 6
chr12_-_122985494	0.39	ENST00000336229.4	ZCCHC8	zinc finger, CCHC domain containing 8
chr9_-_73483958	0.39	ENST00000377101.1 ENST00000377106.1 ENST00000360823.2 ENST00000377105.1	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr3_-_46904918	0.39	ENST00000395869.1	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr19_+_4007644	0.39	ENST00000262971.2	PIAS4	protein inhibitor of activated STAT, 4
chr7_+_111846741	0.39	ENST00000421043.1 ENST00000425229.1 ENST00000450657.1	ZNF277	zinc finger protein 277
chr4_+_41614720	0.38	ENST00000509277.1	LIMCH1	LIM and calponin homology domains 1
chr1_+_14075865	0.38	ENST00000413440.1	PRDM2	PR domain containing 2, with ZNF domain
chr17_-_49124230	0.38	ENST00000510283.1 ENST00000510855.1	SPAG9	sperm associated antigen 9
chr5_-_150521192	0.38	ENST00000523714.1 ENST00000521749.1	ANXA6	annexin A6
chr18_+_32558208	0.37	ENST00000436190.2	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr17_+_26698677	0.37	ENST00000457710.3	SARM1	sterile alpha and TIR motif containing 1
chr11_+_46402482	0.36	ENST00000441869.1	MDK	midkine (neurite growth-promoting factor 2)
chrX_-_131352152	0.36	ENST00000342983.2	RAP2C	RAP2C, member of RAS oncogene family
chr16_+_84801852	0.36	ENST00000569925.1 ENST00000567526.1	USP10	ubiquitin specific peptidase 10
chr6_-_11232891	0.35	ENST00000379433.5 ENST00000379446.5	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr20_-_62284766	0.35	ENST00000370053.1	STMN3	stathmin-like 3
chr1_-_115053781	0.35	ENST00000358465.2 ENST00000369543.2	TRIM33	tripartite motif containing 33
chr3_+_52719936	0.35	ENST00000418458.1 ENST00000394799.2	GNL3	guanine nucleotide binding protein-like 3 (nucleolar)
chr14_+_22984601	0.34	ENST00000390509.1	TRAJ28	T cell receptor alpha joining 28
chr17_-_73389854	0.34	ENST00000578961.1 ENST00000392564.1 ENST00000582582.1	GRB2	growth factor receptor-bound protein 2
chr2_+_198669365	0.34	ENST00000428675.1	PLCL1	phospholipase C-like 1
chr14_+_97263641	0.33	ENST00000216639.3	VRK1	vaccinia related kinase 1
chr2_-_47572105	0.33	ENST00000419035.1 ENST00000448713.1 ENST00000450550.1 ENST00000413185.2	AC073283.4	AC073283.4
chr7_-_25268104	0.32	ENST00000222674.2	NPVF	neuropeptide VF precursor
chr19_+_47105309	0.32	ENST00000599839.1 ENST00000596362.1	CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr14_-_58618896	0.32	ENST00000267485.7	C14orf37	chromosome 14 open reading frame 37
chrX_-_11284095	0.32	ENST00000303025.6 ENST00000534860.1	ARHGAP6	Rho GTPase activating protein 6
chr3_+_183353356	0.32	ENST00000242810.6 ENST00000493074.1 ENST00000437402.1 ENST00000454495.2 ENST00000473045.1 ENST00000468101.1 ENST00000427201.2 ENST00000482138.1 ENST00000454652.2	KLHL24	kelch-like family member 24
chr12_-_122985067	0.31	ENST00000540586.1 ENST00000543897.1	ZCCHC8	zinc finger, CCHC domain containing 8
chr5_-_111092930	0.31	ENST00000257435.7	NREP	neuronal regeneration related protein
chr1_+_66797687	0.31	ENST00000371045.5 ENST00000531025.1 ENST00000526197.1	PDE4B	phosphodiesterase 4B, cAMP-specific
chr6_+_10556215	0.31	ENST00000316170.3	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_-_128568721	0.31	ENST00000322313.4 ENST00000393006.1 ENST00000409658.3 ENST00000436787.1	WDR33	WD repeat domain 33
chr6_+_83777374	0.31	ENST00000349129.2 ENST00000237163.5 ENST00000536812.1	DOPEY1	dopey family member 1

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	4.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	3.3	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.9	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	2.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.6	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	2.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	3.3	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	3.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	2.2	PID E2F PATHWAY	E2F transcription factor network
0.0	1.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.6	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	1.8	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID EPO PATHWAY	EPO signaling pathway
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	1.3	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	1.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	1.2	PID P73PATHWAY	p73 transcription factor network
0.0	0.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.0	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.4	3.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2	1.6	GO:0000322	storage vacuole(GO:0000322)
0.2	0.6	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2	1.8	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.2	1.1	GO:0033269	internode region of axon(GO:0033269)
0.2	2.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.2	2.0	GO:0000815	ESCRT III complex(GO:0000815)
0.1	0.6	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.4	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.1	0.8	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.7	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.4	GO:0060187	cell pole(GO:0060187)
0.1	0.8	GO:0042382	paraspeckles(GO:0042382)
0.1	0.5	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	1.9	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	0.9	GO:0031010	ISWI-type complex(GO:0031010)
0.1	0.7	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.9	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.7	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	1.0	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.4	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.6	GO:0045120	pronucleus(GO:0045120)
0.0	2.5	GO:0005871	kinesin complex(GO:0005871)
0.0	2.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	2.3	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.5	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	1.9	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.4	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0045177	apical part of cell(GO:0045177)
0.0	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.9	GO:0005859	muscle myosin complex(GO:0005859)
0.0	1.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.7	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.6	GO:0032156	septin cytoskeleton(GO:0032156)
0.0	3.5	GO:0005923	bicellular tight junction(GO:0005923)
0.0	1.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	0.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.4	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.2	GO:0016460	myosin II complex(GO:0016460)
0.0	1.5	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	2.3	GO:0005882	intermediate filament(GO:0005882)
0.0	0.4	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	3.6	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.9	GO:0000786	nucleosome(GO:0000786)
0.0	2.0	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.7	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.2	GO:0097386	glial cell projection(GO:0097386)
0.0	0.3	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	1.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.5	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.5	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.7	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.1	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0001069	regulatory region RNA binding(GO:0001069)
0.3	2.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.3	1.3	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.3	2.1	GO:0008142	oxysterol binding(GO:0008142)
0.3	1.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.3	1.5	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.2	1.0	GO:0016211	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2	0.7	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2	0.6	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2	3.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.2	0.8	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.2	1.0	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.2	2.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.6	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	2.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.4	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.1	0.7	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1	2.6	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	1.4	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	1.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.8	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	0.8	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	2.9	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	0.9	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	1.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.7	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.4	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	1.8	GO:0070628	proteasome binding(GO:0070628)
0.1	0.4	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	0.3	GO:0031493	nucleosomal histone binding(GO:0031493)
0.1	0.2	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1	2.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	3.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	2.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	0.4	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.2	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.1	1.0	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	0.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.2	GO:0030350	iron-responsive element binding(GO:0030350)
0.1	0.8	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.9	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.8	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.7	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.4	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
0.0	0.6	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.8	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.6	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	1.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.2	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	1.0	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.4	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.2	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	4.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	3.5	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.4	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.9	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	1.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0003680	AT DNA binding(GO:0003680)
0.0	2.5	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.7	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	1.0	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	1.4	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.5	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.5	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.3	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.5	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.6	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.9	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.9	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.6	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
0.0	0.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	1.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	2.4	GO:0042393	histone binding(GO:0042393)
0.0	0.4	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.5	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	0.6	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.2	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.5	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	3.8	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	0.4	GO:0002039	p53 binding(GO:0002039)
0.0	0.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.9	GO:0050661	NADP binding(GO:0050661)
0.0	0.4	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.1	GO:0046935	phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.4	GO:0005080	protein kinase C binding(GO:0005080)
0.0	2.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0035374	chondroitin sulfate binding(GO:0035374)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	1.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.8	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	3.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	1.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	1.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.2	GO:0071895	odontoblast differentiation(GO:0071895)
0.7	2.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.6	3.1	GO:0001834	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4	1.3	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.4	2.6	GO:1903758	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.4	1.9	GO:0070842	aggresome assembly(GO:0070842)
0.4	1.1	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.4	1.1	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.3	2.0	GO:0051013	microtubule severing(GO:0051013)
0.3	1.6	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3	0.9	GO:0072709	cellular response to sorbitol(GO:0072709)
0.3	0.8	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.3	1.5	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.3	0.8	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.2	1.0	GO:0006542	glutamine biosynthetic process(GO:0006542)
0.2	1.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.2	1.4	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.2	1.1	GO:1904209	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2	1.2	GO:0030421	defecation(GO:0030421)
0.2	0.6	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2	0.6	GO:0090244	trachea cartilage morphogenesis(GO:0060535) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2	0.9	GO:0006740	NADPH regeneration(GO:0006740)
0.2	0.5	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.2	0.5	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2	0.5	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.2	2.3	GO:0070307	lens fiber cell development(GO:0070307)
0.2	2.1	GO:0051382	kinetochore assembly(GO:0051382)
0.2	0.6	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.2	0.8	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2	0.6	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.1	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.1	0.7	GO:1904693	midbrain morphogenesis(GO:1904693)
0.1	0.4	GO:0036060	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1	0.4	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.1	0.4	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.1	0.4	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	0.8	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.4	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	2.2	GO:0021516	dorsal spinal cord development(GO:0021516)
0.1	1.2	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) negative regulation of chromatin silencing(GO:0031936) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	1.4	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.7	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	1.2	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1	0.8	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	2.7	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.3	GO:1901355	response to rapamycin(GO:1901355)
0.1	1.0	GO:1902414	protein localization to cell junction(GO:1902414)
0.1	0.9	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	1.0	GO:0001573	ganglioside metabolic process(GO:0001573)
0.1	0.4	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.3	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.1	0.2	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1	0.2	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.1	0.4	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1	0.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	1.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	0.5	GO:0021764	amygdala development(GO:0021764)
0.1	0.3	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.4	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	0.9	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.1	0.2	GO:0021571	rhombomere 5 development(GO:0021571)
0.1	0.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.9	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.1	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.1	0.2	GO:0060926	atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.1	1.8	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.1	0.4	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	2.4	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	2.6	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	0.1	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.1	0.6	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.2	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0	0.7	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.9	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.2	GO:0072658	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.4	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0	0.5	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.6	GO:0034378	chylomicron assembly(GO:0034378)
0.0	0.7	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.3	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:1904247	modification by virus of host mRNA processing(GO:0046778) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0	2.5	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	1.1	GO:0006825	copper ion transport(GO:0006825)
0.0	1.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	1.9	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	1.3	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.0	0.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	1.5	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.2	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.0	0.4	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	1.0	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.5	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.5	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	1.1	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.2	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.3	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.6	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.6	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.5	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	1.0	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.0	0.3	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.8	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.4	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.3	GO:0015868	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0	0.3	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.2	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.2	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	3.3	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.7	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.8	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.5	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0039656	modulation by virus of host transcription(GO:0019056) modulation by virus of host gene expression(GO:0039656) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0	0.4	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.4	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.0	0.4	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.4	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.5	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.2	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.2	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.5	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.0	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.4	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0034334	adherens junction maintenance(GO:0034334)
0.0	0.4	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.3	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.2	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.2	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.4	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.2	GO:0003382	epithelial cell morphogenesis(GO:0003382)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.3	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.6	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.2	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.5	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.3	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.3	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.9	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.3	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.0	0.2	GO:0003016	respiratory system process(GO:0003016)
0.0	0.1	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.0	0.0	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	1.2	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.3	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
0.0	0.1	GO:0038092	nodal signaling pathway(GO:0038092)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.7	GO:0030218	erythrocyte differentiation(GO:0030218)