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ENCODE cell lines, expression (Ernst 2011)

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Results for SOX21

Z-value: 0.34

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Transcription factors associated with SOX21

Gene Symbol Gene ID Gene Info
ENSG00000125285.4 SOX21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX21hg19_v2_chr13_-_95364389_953643890.001.0e+00Click!

Activity profile of SOX21 motif

Sorted Z-values of SOX21 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX21

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_5005445 0.75 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr6_-_112575912 0.56 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr12_+_69742121 0.38 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr2_+_102759199 0.35 ENST00000409288.1
ENST00000410023.1
IL1R1
interleukin 1 receptor, type I
chr6_-_112575838 0.35 ENST00000455073.1
LAMA4
laminin, alpha 4
chr8_-_19459993 0.29 ENST00000454498.2
ENST00000520003.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr20_+_43343886 0.29 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr5_-_95158644 0.28 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr12_-_7261772 0.28 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr6_-_112575758 0.26 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chrY_+_16634483 0.23 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr7_+_120702819 0.23 ENST00000423795.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr1_+_221051699 0.22 ENST00000366903.6
HLX
H2.0-like homeobox
chr5_-_95158375 0.21 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
GLRX
glutaredoxin (thioltransferase)
chr15_+_58702742 0.18 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr1_-_169455169 0.16 ENST00000367804.4
ENST00000236137.5
SLC19A2
solute carrier family 19 (thiamine transporter), member 2
chr7_-_86849883 0.15 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr3_-_155524049 0.14 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chr6_+_131894284 0.13 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr3_-_37034702 0.13 ENST00000322716.5
EPM2AIP1
EPM2A (laforin) interacting protein 1
chr12_-_10324716 0.12 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr1_+_146714291 0.12 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr12_+_123011776 0.10 ENST00000450485.2
ENST00000333479.7
KNTC1
kinetochore associated 1
chr5_-_55529115 0.10 ENST00000513241.2
ENST00000341048.4
ANKRD55
ankyrin repeat domain 55
chr17_-_18266660 0.10 ENST00000582653.1
ENST00000352886.6
SHMT1
serine hydroxymethyltransferase 1 (soluble)
chr19_+_42381337 0.10 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr6_-_52926539 0.07 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr6_+_42531798 0.06 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr16_-_15149828 0.05 ENST00000566419.1
ENST00000568320.1
NTAN1
N-terminal asparagine amidase
chr19_+_42381173 0.05 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr8_+_67687413 0.04 ENST00000521960.1
ENST00000522398.1
ENST00000522629.1
ENST00000520976.1
ENST00000396596.1
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr9_+_105757590 0.03 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr3_-_186288097 0.03 ENST00000446782.1
TBCCD1
TBCC domain containing 1
chr10_-_71169031 0.03 ENST00000373307.1
TACR2
tachykinin receptor 2
chr15_-_80263506 0.03 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr1_+_158901329 0.02 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr11_-_8285405 0.02 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr1_+_203764742 0.02 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
ZC3H11A
zinc finger CCCH-type containing 11A
chr12_-_89746173 0.02 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr10_-_17243579 0.02 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
TRDMT1
tRNA aspartic acid methyltransferase 1
chr6_+_31371337 0.02 ENST00000449934.2
ENST00000421350.1
MICA
MHC class I polypeptide-related sequence A
chr3_-_164875850 0.01 ENST00000472120.1
RP11-747D18.1
RP11-747D18.1
chr4_-_122854193 0.01 ENST00000513531.1
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr20_+_56964253 0.01 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr1_+_151171012 0.01 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr4_+_81951957 0.01 ENST00000282701.2
BMP3
bone morphogenetic protein 3
chrX_+_2984874 0.01 ENST00000359361.2
ARSF
arylsulfatase F
chr14_-_107170409 0.01 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr2_+_3705785 0.00 ENST00000252505.3
ALLC
allantoicase
chr1_+_67632083 0.00 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chrX_-_153210107 0.00 ENST00000369997.3
ENST00000393700.3
ENST00000412763.1
RENBP
renin binding protein
chr12_-_1058685 0.00 ENST00000397230.2
ENST00000542785.1
ENST00000544742.1
ENST00000536177.1
ENST00000539046.1
ENST00000541619.1
RAD52
RAD52 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0047023 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 0.3 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.2 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.8 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.2 GO:0015888 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.5 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.1 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.0 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates