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ENCODE cell lines, expression (Ernst 2011)

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Results for SOX7

Z-value: 0.65

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
SOX7
ENSG00000171056.6 SOX7
SOX7
ENSG00000258724.1 SOX7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10588010_105880300.322.3e-01Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_95158644 1.50 ENST00000237858.6
 GLRX
 glutaredoxin (thioltransferase)
chr22_+_23101182 1.32 ENST00000390312.2
 IGLV2-14
 immunoglobulin lambda variable 2-14
chr14_-_106573756 1.17 ENST00000390601.2
 IGHV3-11
 immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr5_-_95158375 0.96 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX
 glutaredoxin (thioltransferase)
chr11_+_7618413 0.87 ENST00000528883.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr21_-_15918618 0.69 ENST00000400564.1
ENST00000400566.1
 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
chr21_+_34144411 0.56 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
 C21orf49
 chromosome 21 open reading frame 49
chr6_-_111804905 0.52 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr8_-_102803163 0.51 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
 NCALD
 neurocalcin delta
chr1_+_100598691 0.50 ENST00000370143.1
ENST00000370141.2
 TRMT13
 tRNA methyltransferase 13 homolog (S. cerevisiae)
chr12_-_90049878 0.46 ENST00000359142.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr12_-_90049828 0.41 ENST00000261173.2
ENST00000348959.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr16_+_33020496 0.40 ENST00000565407.2
 IGHV3OR16-8
 immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr19_-_22379753 0.34 ENST00000397121.2
 ZNF676
 zinc finger protein 676
chr16_-_33647696 0.32 ENST00000558425.1
ENST00000569103.2
 RP11-812E19.9
 Uncharacterized protein
chr8_+_77593448 0.31 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr10_+_5005445 0.29 ENST00000380872.4
 AKR1C1
 aldo-keto reductase family 1, member C1
chr12_-_57443886 0.27 ENST00000300119.3
 MYO1A
 myosin IA
chr6_+_131894284 0.25 ENST00000368087.3
ENST00000356962.2
 ARG1
 arginase 1
chr10_-_5046042 0.25 ENST00000421196.3
ENST00000455190.1
 AKR1C2
 aldo-keto reductase family 1, member C2
chr2_-_166930131 0.18 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A
 sodium channel, voltage-gated, type I, alpha subunit
chrX_+_69353284 0.17 ENST00000342206.6
ENST00000356413.4
 IGBP1
 immunoglobulin (CD79A) binding protein 1
chr6_+_42531798 0.15 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr18_+_32820990 0.15 ENST00000601719.1
ENST00000591206.1
ENST00000330501.7
ENST00000261333.6
ENST00000355632.4
ENST00000585800.1
 ZNF397
 zinc finger protein 397
chr1_+_10509971 0.14 ENST00000320498.4
 CORT
 cortistatin
chr5_+_175511859 0.12 ENST00000503724.2
ENST00000253490.4
 FAM153B
 family with sequence similarity 153, member B
chr12_-_58027138 0.11 ENST00000341156.4
 B4GALNT1
 beta-1,4-N-acetyl-galactosaminyl transferase 1
chr9_-_70465758 0.10 ENST00000489273.1
 CBWD5
 COBW domain containing 5
chr10_+_96162242 0.10 ENST00000225235.4
 TBC1D12
 TBC1 domain family, member 12
chr17_-_66951474 0.10 ENST00000269080.2
 ABCA8
 ATP-binding cassette, sub-family A (ABC1), member 8
chr8_+_12803176 0.09 ENST00000524591.2
 KIAA1456
 KIAA1456
chr4_+_76995855 0.08 ENST00000355810.4
ENST00000349321.3
 ART3
 ADP-ribosyltransferase 3
chr6_+_150690028 0.08 ENST00000229447.5
ENST00000344419.3
 IYD
 iodotyrosine deiodinase
chr6_+_150690133 0.07 ENST00000392255.3
ENST00000500320.3
 IYD
 iodotyrosine deiodinase
chr15_+_59439899 0.07 ENST00000599727.1
 C15ORF31
 C15ORF31
chr6_+_29555683 0.06 ENST00000383640.2
 OR2H2
 olfactory receptor, family 2, subfamily H, member 2
chr9_+_105757590 0.05 ENST00000374798.3
ENST00000487798.1
 CYLC2
 cylicin, basic protein of sperm head cytoskeleton 2
chr8_-_19459993 0.05 ENST00000454498.2
ENST00000520003.1
 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr1_+_11724167 0.05 ENST00000376753.4
 FBXO6
 F-box protein 6
chr1_-_54303934 0.05 ENST00000537333.1
 NDC1
 NDC1 transmembrane nucleoporin
chr4_-_47983519 0.03 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1
 cyclic nucleotide gated channel alpha 1
chr5_+_161494521 0.03 ENST00000356592.3
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_-_88285309 0.02 ENST00000420840.2
 RGPD2
 RANBP2-like and GRIP domain containing 2
chr6_-_46048116 0.02 ENST00000185206.6
 CLIC5
 chloride intracellular channel 5
chr6_-_132910877 0.01 ENST00000258034.2
 TAAR5
 trace amine associated receptor 5
chr14_+_50291993 0.00 ENST00000595378.1
 AL627171.2
 HCG1786899; PRO2610; Uncharacterized protein
chr16_-_20364030 0.00 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
 UMOD
 uromodulin
chr5_+_161494770 0.00 ENST00000414552.2
ENST00000361925.4
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 2.5 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.3 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 2.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.7 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0060632 regulation of microtubule-based movement(GO:0060632)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0033150 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 0.0 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.2 GO:0043194 voltage-gated sodium channel complex(GO:0001518) axon initial segment(GO:0043194)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.5 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 2.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)