ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
SPI1 Links Ensembl NCBI GeneCards UniProt	ENSG00000066336.7	SPI1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SPI1	hg19_v2_chr11_-_47399942_47399961, hg19_v2_chr11_-_47400078_47400127	0.76	5.8e-04	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr13_-_46756351	12.92	ENST00000323076.2	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_198608146	11.93	ENST00000367376.2 ENST00000352140.3 ENST00000594404.1 ENST00000598951.1 ENST00000530727.1 ENST00000442510.2 ENST00000367367.4 ENST00000348564.6 ENST00000367364.1 ENST00000413409.2	PTPRC	protein tyrosine phosphatase, receptor type, C
chr10_-_98031310	10.02	ENST00000427367.2 ENST00000413476.2	BLNK	B-cell linker
chr10_-_98031265	9.70	ENST00000224337.5 ENST00000371176.2	BLNK	B-cell linker
chr3_-_121379739	8.91	ENST00000428394.2 ENST00000314583.3	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr12_-_15114492	8.65	ENST00000541546.1	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr12_-_15114603	8.58	ENST00000228945.4	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr11_+_60223225	8.11	ENST00000524807.1 ENST00000345732.4	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr11_+_60223312	8.10	ENST00000532491.1 ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr1_-_207095324	7.93	ENST00000530505.1 ENST00000367091.3 ENST00000442471.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr2_+_33661382	7.53	ENST00000402538.3	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr17_-_62084241	7.40	ENST00000449662.2	ICAM2	intercellular adhesion molecule 2
chr1_-_183560011	7.20	ENST00000367536.1	NCF2	neutrophil cytosolic factor 2
chr1_+_111415757	6.98	ENST00000429072.2 ENST00000271324.5	CD53	CD53 molecule
chr2_-_175499294	6.74	ENST00000392547.2	WIPF1	WAS/WASL interacting protein family, member 1
chr1_-_207095212	6.74	ENST00000420007.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr21_-_15918618	6.71	ENST00000400564.1 ENST00000400566.1	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr20_+_44746885	6.62	ENST00000372285.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr14_-_23285011	6.29	ENST00000397532.3	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr15_-_80263506	6.16	ENST00000335661.6	BCL2A1	BCL2-related protein A1
chr14_-_23285069	6.10	ENST00000554758.1 ENST00000397528.4	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_-_183559693	5.86	ENST00000367535.3 ENST00000413720.1 ENST00000418089.1	NCF2	neutrophil cytosolic factor 2
chr8_+_56792355	5.81	ENST00000519728.1	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr20_+_44746939	5.79	ENST00000372276.3	CD40	CD40 molecule, TNF receptor superfamily member 5
chr1_-_150738261	5.76	ENST00000448301.2 ENST00000368985.3	CTSS	cathepsin S
chr2_+_143886877	5.70	ENST00000295095.6	ARHGAP15	Rho GTPase activating protein 15
chr6_-_154677900	5.68	ENST00000265198.4 ENST00000520261.1	IPCEF1	interaction protein for cytohesin exchange factors 1
chr11_+_128563652	5.53	ENST00000527786.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr6_-_32160622	5.51	ENST00000487761.1 ENST00000375040.3	GPSM3	G-protein signaling modulator 3
chr4_-_40631859	5.32	ENST00000295971.7 ENST00000319592.4	RBM47	RNA binding motif protein 47
chr5_-_88178964	5.27	ENST00000513252.1 ENST00000508569.1 ENST00000510942.1 ENST00000506554.1	MEF2C	myocyte enhancer factor 2C
chr18_-_53177984	5.27	ENST00000543082.1	TCF4	transcription factor 4
chr5_-_169725231	5.25	ENST00000046794.5	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_+_25205568	5.17	ENST00000548766.1 ENST00000556887.1	LRMP	lymphoid-restricted membrane protein
chr12_+_25205666	5.14	ENST00000547044.1	LRMP	lymphoid-restricted membrane protein
chr8_+_56792377	5.13	ENST00000520220.2	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_-_25256368	5.09	ENST00000308873.6	RUNX3	runt-related transcription factor 3
chr17_-_29641104	5.01	ENST00000577894.1 ENST00000330927.4	EVI2B	ecotropic viral integration site 2B
chr15_+_81589254	5.00	ENST00000394652.2	IL16	interleukin 16
chr19_+_42381173	5.00	ENST00000221972.3	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr12_+_54891495	4.92	ENST00000293373.6	NCKAP1L	NCK-associated protein 1-like
chr12_+_7055767	4.87	ENST00000447931.2	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr12_+_7055631	4.86	ENST00000543115.1 ENST00000399448.1	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chrX_+_128913906	4.76	ENST00000356892.3	SASH3	SAM and SH3 domain containing 3
chr5_-_88179017	4.73	ENST00000514028.1 ENST00000514015.1 ENST00000503075.1 ENST00000437473.2	MEF2C	myocyte enhancer factor 2C
chr2_-_96811170	4.68	ENST00000288943.4	DUSP2	dual specificity phosphatase 2
chr1_-_111743285	4.64	ENST00000357640.4	DENND2D	DENN/MADD domain containing 2D
chr6_+_31543334	4.47	ENST00000449264.2	TNF	tumor necrosis factor
chr5_-_88179302	4.46	ENST00000504921.2	MEF2C	myocyte enhancer factor 2C
chr22_-_37545972	4.43	ENST00000216223.5	IL2RB	interleukin 2 receptor, beta
chr12_+_25205446	4.39	ENST00000557489.1 ENST00000354454.3 ENST00000536173.1	LRMP	lymphoid-restricted membrane protein
chr1_-_31230650	4.39	ENST00000294507.3	LAPTM5	lysosomal protein transmembrane 5
chr16_-_89043377	4.11	ENST00000436887.2 ENST00000448839.1 ENST00000360302.2	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr11_-_3862059	4.10	ENST00000396978.1	RHOG	ras homolog family member G
chr17_-_29641084	4.04	ENST00000544462.1	EVI2B	ecotropic viral integration site 2B
chr3_-_16555150	4.00	ENST00000334133.4	RFTN1	raftlin, lipid raft linker 1
chr17_+_72462525	3.98	ENST00000360141.3	CD300A	CD300a molecule
chr5_+_169064245	3.98	ENST00000256935.8	DOCK2	dedicator of cytokinesis 2
chr17_-_38721711	3.90	ENST00000578085.1 ENST00000246657.2	CCR7	chemokine (C-C motif) receptor 7
chr19_+_42381337	3.77	ENST00000597454.1 ENST00000444740.2	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr16_-_89043605	3.70	ENST00000268679.4	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr17_-_34417479	3.68	ENST00000225245.5	CCL3	chemokine (C-C motif) ligand 3
chr11_-_3862206	3.64	ENST00000351018.4	RHOG	ras homolog family member G
chr19_+_49838653	3.57	ENST00000598095.1 ENST00000426897.2 ENST00000323906.4 ENST00000535669.2 ENST00000597602.1 ENST00000595660.1	CD37	CD37 molecule
chr1_+_32716840	3.53	ENST00000336890.5	LCK	lymphocyte-specific protein tyrosine kinase
chr2_-_64371546	3.51	ENST00000358912.4	PELI1	pellino E3 ubiquitin protein ligase 1
chr4_+_68424434	3.49	ENST00000265404.2 ENST00000396225.1	STAP1	signal transducing adaptor family member 1
chr22_-_37640277	3.49	ENST00000401529.3 ENST00000249071.6	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_6481776	3.49	ENST00000543576.1 ENST00000590173.1 ENST00000381480.2	DENND1C	DENN/MADD domain containing 1C
chr17_+_72462766	3.48	ENST00000392625.3 ENST00000361933.3 ENST00000310828.5	CD300A	CD300a molecule
chrX_-_70331298	3.45	ENST00000456850.2 ENST00000473378.1 ENST00000487883.1 ENST00000374202.2	IL2RG	interleukin 2 receptor, gamma
chr16_+_30483962	3.44	ENST00000356798.6	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_+_32716857	3.30	ENST00000482949.1 ENST00000495610.2	LCK	lymphocyte-specific protein tyrosine kinase
chr22_-_37640456	3.22	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_+_32739733	3.21	ENST00000333070.4	LCK	lymphocyte-specific protein tyrosine kinase
chr18_-_53070913	3.20	ENST00000568186.1 ENST00000564228.1	TCF4	transcription factor 4
chr18_-_53068911	3.17	ENST00000537856.3	TCF4	transcription factor 4
chr11_+_128563948	3.14	ENST00000534087.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr11_+_102188224	3.13	ENST00000263464.3	BIRC3	baculoviral IAP repeat containing 3
chrX_+_78200913	3.07	ENST00000171757.2	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr9_+_2158485	3.04	ENST00000417599.1 ENST00000382185.1 ENST00000382183.1	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_+_102188272	3.04	ENST00000532808.1	BIRC3	baculoviral IAP repeat containing 3
chr9_+_2158443	3.01	ENST00000302401.3 ENST00000324954.5 ENST00000423555.1 ENST00000382186.1	SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_+_78200829	2.99	ENST00000544091.1	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr1_+_236305826	2.98	ENST00000366592.3 ENST00000366591.4	GPR137B	G protein-coupled receptor 137B
chr19_+_6772710	2.89	ENST00000304076.2 ENST00000602142.1 ENST00000596764.1	VAV1	vav 1 guanine nucleotide exchange factor
chr12_-_53601055	2.89	ENST00000552972.1 ENST00000422257.3 ENST00000267082.5	ITGB7	integrin, beta 7
chr12_-_53601000	2.86	ENST00000338737.4 ENST00000549086.2	ITGB7	integrin, beta 7
chr2_-_175462934	2.84	ENST00000392546.2 ENST00000436221.1	WIPF1	WAS/WASL interacting protein family, member 1
chr6_+_32811885	2.83	ENST00000458296.1 ENST00000413039.1 ENST00000429600.1 ENST00000412095.1 ENST00000415067.1 ENST00000395330.1	TAPSAR1 PSMB9	TAP1 and PSMB8 antisense RNA 1 proteasome (prosome, macropain) subunit, beta type, 9
chr18_-_53069419	2.77	ENST00000570177.2	TCF4	transcription factor 4
chr8_-_82395461	2.76	ENST00000256104.4	FABP4	fatty acid binding protein 4, adipocyte
chr11_-_58343319	2.75	ENST00000395074.2	LPXN	leupaxin
chr7_-_5569588	2.72	ENST00000417101.1	ACTB	actin, beta
chr15_+_75074410	2.71	ENST00000439220.2	CSK	c-src tyrosine kinase
chr22_+_37257015	2.65	ENST00000447071.1 ENST00000248899.6 ENST00000397147.4	NCF4	neutrophil cytosolic factor 4, 40kDa
chr3_-_105588231	2.60	ENST00000545639.1 ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr1_+_161632937	2.58	ENST00000236937.9 ENST00000367961.4 ENST00000358671.5	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr3_+_142838091	2.56	ENST00000309575.3	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr2_-_175462456	2.47	ENST00000409891.1 ENST00000410117.1	WIPF1	WAS/WASL interacting protein family, member 1
chr6_-_32811771	2.47	ENST00000395339.3 ENST00000374882.3	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8
chr15_+_75335604	2.46	ENST00000563393.1	PPCDC	phosphopantothenoylcysteine decarboxylase
chr14_-_23451467	2.46	ENST00000555074.1 ENST00000361265.4	RP11-298I3.5 AJUBA	RP11-298I3.5 ajuba LIM protein
chr19_-_10450328	2.41	ENST00000160262.5	ICAM3	intercellular adhesion molecule 3
chr18_-_52989217	2.36	ENST00000570287.2	TCF4	transcription factor 4
chr19_-_10450287	2.36	ENST00000589261.1 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3	intercellular adhesion molecule 3
chr3_+_119316689	2.36	ENST00000273371.4	PLA1A	phospholipase A1 member A
chr15_+_75074385	2.32	ENST00000220003.9	CSK	c-src tyrosine kinase
chr10_+_12391481	2.32	ENST00000378847.3	CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr18_-_52989525	2.31	ENST00000457482.3	TCF4	transcription factor 4
chr19_+_1077393	2.27	ENST00000590577.1	HMHA1	histocompatibility (minor) HA-1
chr4_+_103423055	2.25	ENST00000505458.1	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_+_31582961	2.25	ENST00000376059.3 ENST00000337917.7	AIF1	allograft inflammatory factor 1
chr1_-_184943610	2.24	ENST00000367511.3	FAM129A	family with sequence similarity 129, member A
chr1_-_202129704	2.22	ENST00000476061.1 ENST00000544762.1 ENST00000467283.1 ENST00000464870.1 ENST00000435759.2 ENST00000486116.1 ENST00000543735.1 ENST00000308986.5 ENST00000477625.1	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr4_+_103422471	2.22	ENST00000226574.4 ENST00000394820.4	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr8_+_86089460	2.22	ENST00000418930.2	E2F5	E2F transcription factor 5, p130-binding
chr17_-_20370847	2.21	ENST00000423676.3 ENST00000324290.5	LGALS9B	lectin, galactoside-binding, soluble, 9B
chrX_+_48542168	2.20	ENST00000376701.4	WAS	Wiskott-Aldrich syndrome
chr12_-_92539614	2.15	ENST00000256015.3	BTG1	B-cell translocation gene 1, anti-proliferative
chr6_+_26156551	2.15	ENST00000304218.3	HIST1H1E	histone cluster 1, H1e
chr7_-_37488834	2.12	ENST00000310758.4	ELMO1	engulfment and cell motility 1
chr7_+_74188309	2.07	ENST00000289473.4 ENST00000433458.1	NCF1	neutrophil cytosolic factor 1
chr17_-_16875371	2.03	ENST00000437538.2 ENST00000583789.1 ENST00000261652.2 ENST00000579315.1	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr3_-_98241358	1.98	ENST00000503004.1 ENST00000506575.1 ENST00000513452.1 ENST00000515620.1	CLDND1	claudin domain containing 1
chr2_+_198669365	1.98	ENST00000428675.1	PLCL1	phospholipase C-like 1
chr2_+_182321925	1.93	ENST00000339307.4 ENST00000397033.2	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr7_+_50344289	1.93	ENST00000413698.1 ENST00000359197.5 ENST00000331340.3 ENST00000357364.4 ENST00000343574.5 ENST00000349824.4 ENST00000346667.4 ENST00000440768.2	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr1_-_154909329	1.91	ENST00000368467.3	PMVK	phosphomevalonate kinase
chr2_-_214016314	1.91	ENST00000434687.1 ENST00000374319.4	IKZF2	IKAROS family zinc finger 2 (Helios)
chr7_+_99971129	1.91	ENST00000394000.2 ENST00000350573.2	PILRA	paired immunoglobin-like type 2 receptor alpha
chr2_-_225811747	1.87	ENST00000409592.3	DOCK10	dedicator of cytokinesis 10
chr12_-_6233828	1.83	ENST00000572068.1 ENST00000261405.5	VWF	von Willebrand factor
chr3_+_119316721	1.83	ENST00000488919.1 ENST00000495992.1	PLA1A	phospholipase A1 member A
chr7_-_120498357	1.82	ENST00000415871.1 ENST00000222747.3 ENST00000430985.1	TSPAN12	tetraspanin 12
chr10_-_121302195	1.82	ENST00000369103.2	RGS10	regulator of G-protein signaling 10
chr22_+_40322595	1.80	ENST00000420971.1 ENST00000544756.1	GRAP2	GRB2-related adaptor protein 2
chr22_+_40322623	1.78	ENST00000399090.2	GRAP2	GRB2-related adaptor protein 2
chr11_+_19138670	1.78	ENST00000446113.2 ENST00000399351.3	ZDHHC13	zinc finger, DHHC-type containing 13
chr1_-_226926864	1.77	ENST00000429204.1 ENST00000366784.1	ITPKB	inositol-trisphosphate 3-kinase B
chr8_+_86089619	1.76	ENST00000256117.5 ENST00000416274.2	E2F5	E2F transcription factor 5, p130-binding
chr4_+_106629929	1.75	ENST00000512828.1 ENST00000394730.3 ENST00000507281.1 ENST00000515279.1	GSTCD	glutathione S-transferase, C-terminal domain containing
chr17_-_41738931	1.72	ENST00000329168.3 ENST00000549132.1	MEOX1	mesenchyme homeobox 1
chr8_+_27183033	1.72	ENST00000420218.2	PTK2B	protein tyrosine kinase 2 beta
chr5_-_131826457	1.72	ENST00000437654.1 ENST00000245414.4	IRF1	interferon regulatory factor 1
chr14_+_88471468	1.71	ENST00000267549.3	GPR65	G protein-coupled receptor 65
chr19_-_47220335	1.71	ENST00000601806.1 ENST00000593363.1 ENST00000598633.1 ENST00000595515.1 ENST00000433867.1	PRKD2	protein kinase D2
chr12_+_11802753	1.70	ENST00000396373.4	ETV6	ets variant 6
chr14_-_35344093	1.70	ENST00000382422.2	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr1_+_66797687	1.67	ENST00000371045.5 ENST00000531025.1 ENST00000526197.1	PDE4B	phosphodiesterase 4B, cAMP-specific
chr3_+_151986709	1.67	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1	muscleblind-like splicing regulator 1
chr16_+_67063262	1.66	ENST00000565389.1	CBFB	core-binding factor, beta subunit
chr1_-_150669500	1.64	ENST00000271732.3	GOLPH3L	golgi phosphoprotein 3-like
chr17_+_43299241	1.63	ENST00000328118.3	FMNL1	formin-like 1
chr1_+_43766642	1.63	ENST00000372476.3	TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr3_-_98241760	1.62	ENST00000507874.1 ENST00000502299.1 ENST00000508659.1 ENST00000510545.1 ENST00000511667.1 ENST00000394185.2 ENST00000394181.2 ENST00000508902.1 ENST00000341181.6 ENST00000437922.1 ENST00000394180.2	CLDND1	claudin domain containing 1
chr3_+_48507210	1.61	ENST00000433541.1 ENST00000422277.2 ENST00000436480.2 ENST00000444177.1	TREX1	three prime repair exonuclease 1
chr17_+_43299156	1.57	ENST00000331495.3	FMNL1	formin-like 1
chr19_+_36203830	1.53	ENST00000262630.3	ZBTB32	zinc finger and BTB domain containing 32
chr16_-_88717482	1.53	ENST00000261623.3	CYBA	cytochrome b-245, alpha polypeptide
chr14_+_102276192	1.52	ENST00000557714.1	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr15_-_55611306	1.50	ENST00000563262.1	RAB27A	RAB27A, member RAS oncogene family
chr2_+_231280908	1.50	ENST00000427101.2 ENST00000432979.1	SP100	SP100 nuclear antigen
chr8_+_27182862	1.50	ENST00000521164.1 ENST00000346049.5	PTK2B	protein tyrosine kinase 2 beta
chr19_-_19754404	1.49	ENST00000587205.1 ENST00000445806.2 ENST00000203556.4	GMIP	GEM interacting protein
chr19_-_8642289	1.48	ENST00000596675.1 ENST00000338257.8	MYO1F	myosin IF
chr1_-_202129105	1.47	ENST00000367279.4	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr6_-_42016385	1.47	ENST00000502771.1 ENST00000508143.1 ENST00000514588.1 ENST00000510503.1 ENST00000415497.2 ENST00000372988.4	CCND3	cyclin D3
chr21_-_46340770	1.44	ENST00000397854.3	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_160549235	1.44	ENST00000368054.3 ENST00000368048.3 ENST00000311224.4 ENST00000368051.3 ENST00000534968.1	CD84	CD84 molecule
chrX_+_37639264	1.44	ENST00000378588.4	CYBB	cytochrome b-245, beta polypeptide
chr16_-_88717423	1.43	ENST00000568278.1 ENST00000569359.1 ENST00000567174.1	CYBA	cytochrome b-245, alpha polypeptide
chr16_-_68002456	1.43	ENST00000576616.1 ENST00000572037.1 ENST00000338335.3 ENST00000422611.2 ENST00000316341.3	SLC12A4	solute carrier family 12 (potassium/chloride transporter), member 4
chr11_+_22688150	1.42	ENST00000454584.2	GAS2	growth arrest-specific 2
chr3_+_113465866	1.41	ENST00000273398.3 ENST00000538620.1 ENST00000496747.1 ENST00000475322.1	ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr9_+_77703414	1.40	ENST00000346234.6	OSTF1	osteoclast stimulating factor 1
chr8_+_74903580	1.40	ENST00000284818.2 ENST00000518893.1	LY96	lymphocyte antigen 96
chr12_+_98909260	1.36	ENST00000556029.1	TMPO	thymopoietin
chr1_+_161551101	1.35	ENST00000367962.4 ENST00000367960.5 ENST00000403078.3 ENST00000428605.2	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr2_+_97203082	1.35	ENST00000454558.2	ARID5A	AT rich interactive domain 5A (MRF1-like)
chr12_-_118797475	1.35	ENST00000541786.1 ENST00000419821.2 ENST00000541878.1	TAOK3	TAO kinase 3
chr3_+_20081515	1.35	ENST00000263754.4	KAT2B	K(lysine) acetyltransferase 2B
chr17_-_37934466	1.34	ENST00000583368.1	IKZF3	IKAROS family zinc finger 3 (Aiolos)
chr12_+_94071341	1.34	ENST00000542893.2	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain
chr13_+_111806083	1.31	ENST00000375736.4	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr13_+_111806055	1.30	ENST00000218789.5	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr4_-_10117949	1.30	ENST00000508079.1	WDR1	WD repeat domain 1
chr11_+_65407331	1.30	ENST00000527525.1	SIPA1	signal-induced proliferation-associated 1
chr7_-_26904317	1.29	ENST00000345317.2	SKAP2	src kinase associated phosphoprotein 2
chr8_+_110552337	1.29	ENST00000337573.5	EBAG9	estrogen receptor binding site associated, antigen, 9
chr16_+_29674277	1.29	ENST00000395389.2	SPN	sialophorin
chr3_-_46249878	1.28	ENST00000296140.3	CCR1	chemokine (C-C motif) receptor 1
chr1_-_159894319	1.26	ENST00000320307.4	TAGLN2	transgelin 2
chr16_+_30484021	1.26	ENST00000358164.5	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr8_+_110551925	1.26	ENST00000395785.2	EBAG9	estrogen receptor binding site associated, antigen, 9
chr7_+_101928380	1.25	ENST00000536178.1	SH2B2	SH2B adaptor protein 2
chr11_+_1874200	1.24	ENST00000311604.3	LSP1	lymphocyte-specific protein 1
chr7_+_99971068	1.24	ENST00000198536.2 ENST00000453419.1	PILRA	paired immunoglobin-like type 2 receptor alpha
chr1_+_186798073	1.23	ENST00000367466.3 ENST00000442353.2	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr6_-_6007200	1.22	ENST00000244766.2	NRN1	neuritin 1

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	17.8	GO:0032010	phagolysosome(GO:0032010)
2.2	10.9	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
1.9	7.7	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
1.8	12.4	GO:0043196	varicosity(GO:0043196)
1.4	1.4	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
1.3	8.8	GO:0019815	B cell receptor complex(GO:0019815)
1.0	5.2	GO:0036398	TCR signalosome(GO:0036398)
1.0	6.1	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
1.0	20.1	GO:0001891	phagocytic cup(GO:0001891)
0.8	5.8	GO:0036021	endolysosome lumen(GO:0036021)
0.8	9.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.8	9.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.7	5.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.6	8.7	GO:0031209	SCAR complex(GO:0031209)
0.4	5.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.4	9.2	GO:0000242	pericentriolar material(GO:0000242)
0.4	7.8	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4	1.1	GO:0043291	RAVE complex(GO:0043291)
0.4	2.6	GO:0030870	Mre11 complex(GO:0030870)
0.3	4.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.3	1.0	GO:0072563	endothelial microparticle(GO:0072563)
0.3	2.6	GO:0000322	storage vacuole(GO:0000322)
0.3	1.0	GO:0070195	growth hormone receptor complex(GO:0070195)
0.3	3.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.3	1.4	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.3	1.3	GO:0042643	actomyosin, actin portion(GO:0042643)
0.3	6.0	GO:0071564	npBAF complex(GO:0071564)
0.2	1.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.2	0.7	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2	1.0	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2	3.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	2.7	GO:0097433	dense body(GO:0097433)
0.2	1.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.2	9.8	GO:0001772	immunological synapse(GO:0001772)
0.2	0.8	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.2	0.6	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2	3.2	GO:0032059	bleb(GO:0032059)
0.2	13.8	GO:0035577	azurophil granule membrane(GO:0035577)
0.2	1.4	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.2	1.4	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.2	1.2	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2	1.2	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.2	2.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.2	4.2	GO:0002080	acrosomal membrane(GO:0002080)
0.2	2.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	1.6	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.2	1.7	GO:0031010	ISWI-type complex(GO:0031010)
0.2	0.5	GO:0070939	Dsl1p complex(GO:0070939)
0.1	1.3	GO:0000125	PCAF complex(GO:0000125)
0.1	1.9	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	1.0	GO:0044294	dendritic growth cone(GO:0044294)
0.1	1.2	GO:0032039	integrator complex(GO:0032039)
0.1	0.9	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	4.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.8	GO:0072487	MSL complex(GO:0072487)
0.1	1.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.7	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	18.8	GO:0032993	protein-DNA complex(GO:0032993)
0.1	9.0	GO:0070821	tertiary granule membrane(GO:0070821)
0.1	0.8	GO:0071439	clathrin complex(GO:0071439)
0.1	0.5	GO:0033263	CORVET complex(GO:0033263)
0.1	1.9	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	1.4	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	1.5	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	0.8	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.6	GO:0097427	microtubule bundle(GO:0097427)
0.1	0.7	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	26.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	0.3	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.1	0.5	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	0.4	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1	4.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	0.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.4	GO:0071817	MMXD complex(GO:0071817)
0.1	3.1	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.1	0.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.3	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	1.7	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	0.9	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	2.7	GO:0002102	podosome(GO:0002102)
0.1	0.3	GO:0032584	growth cone membrane(GO:0032584)
0.1	1.4	GO:0000145	exocyst(GO:0000145)
0.1	1.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.1	4.2	GO:0035580	specific granule lumen(GO:0035580)
0.1	0.2	GO:0033011	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.1	0.3	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	1.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.9	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	17.3	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	0.6	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.4	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0	2.0	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	1.1	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.0	18.6	GO:0016607	nuclear speck(GO:0016607)
0.0	3.1	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.0	1.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0032021	NELF complex(GO:0032021)
0.0	0.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.3	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	1.3	GO:0045202	synapse(GO:0045202)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	5.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.4	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	3.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	1.8	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	3.0	GO:0043679	axon terminus(GO:0043679)
0.0	4.2	GO:0030667	secretory granule membrane(GO:0030667)
0.0	1.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	5.2	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.2	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0	0.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.2	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	1.0	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.8	GO:0015030	Cajal body(GO:0015030)
0.0	3.9	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.2	GO:0005871	kinesin complex(GO:0005871)
0.0	0.2	GO:0097255	R2TP complex(GO:0097255)
0.0	0.9	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	3.2	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.8	GO:0000785	chromatin(GO:0000785)
0.0	1.5	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.9	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	1.9	GO:0000793	condensed chromosome(GO:0000793)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	33.6	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.6	51.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.5	9.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5	30.7	PID BCR 5PATHWAY	BCR signaling pathway
0.5	4.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	22.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.5	22.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.4	10.8	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.4	14.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.3	24.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	4.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.3	11.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	11.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	17.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	1.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	18.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	4.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	1.9	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	1.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	3.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	13.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.1	2.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	0.6	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	7.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	2.0	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	1.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	1.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	3.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	3.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	4.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	1.7	PID IFNG PATHWAY	IFN-gamma pathway
0.1	0.4	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	1.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	0.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	0.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	2.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	5.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	2.0	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.3	PID ENDOTHELIN PATHWAY	Endothelins
0.0	1.1	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.6	PID REELIN PATHWAY	Reelin signaling pathway
0.0	1.7	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.6	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.1	PID ATR PATHWAY	ATR signaling pathway
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.4	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	18.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
2.0	7.9	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.7	17.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
1.7	10.0	GO:0042610	CD8 receptor binding(GO:0042610)
1.6	11.5	GO:0043208	glycosphingolipid binding(GO:0043208)
1.6	4.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.5	19.1	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.3	24.8	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.1	12.4	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
1.1	3.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.0	3.9	GO:0019770	IgG receptor activity(GO:0019770)
0.9	6.1	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.9	14.8	GO:0003680	AT DNA binding(GO:0003680)
0.8	15.3	GO:0005522	profilin binding(GO:0005522)
0.7	3.7	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.7	4.7	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.6	1.9	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.6	1.9	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.6	16.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.6	17.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.6	7.5	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.6	1.7	GO:0001069	regulatory region RNA binding(GO:0001069)
0.5	2.7	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.5	2.2	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.5	2.0	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.5	3.3	GO:0042608	T cell receptor binding(GO:0042608)
0.4	5.7	GO:0005344	oxygen transporter activity(GO:0005344)
0.4	5.2	GO:0019957	C-C chemokine binding(GO:0019957)
0.4	7.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.4	1.2	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4	7.9	GO:0051400	BH domain binding(GO:0051400)
0.4	2.3	GO:0070513	death domain binding(GO:0070513)
0.4	1.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.4	2.6	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.4	0.4	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.3	0.3	GO:0035004	phosphatidylinositol 3-kinase activity(GO:0035004)
0.3	5.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.3	2.6	GO:0070087	chromo shadow domain binding(GO:0070087)
0.3	1.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3	4.9	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.3	1.3	GO:0004132	dCMP deaminase activity(GO:0004132)
0.3	5.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.3	6.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3	1.8	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3	1.4	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3	1.3	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3	1.6	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.3	0.8	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.3	0.8	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.3	7.8	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3	11.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.2	1.5	GO:0098821	BMP receptor activity(GO:0098821)
0.2	1.0	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.2	0.7	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2	3.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	1.9	GO:1990405	protein antigen binding(GO:1990405)
0.2	1.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2	3.0	GO:0030957	Tat protein binding(GO:0030957)
0.2	1.2	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.2	0.8	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2	1.0	GO:0097108	hedgehog family protein binding(GO:0097108)
0.2	4.8	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.2	8.1	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	5.3	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2	7.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2	1.4	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2	1.0	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2	3.4	GO:0071837	HMG box domain binding(GO:0071837)
0.2	0.5	GO:0031691	alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) platelet activating factor receptor binding(GO:0031859)
0.2	4.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.2	5.8	GO:0043236	laminin binding(GO:0043236)
0.2	1.4	GO:0015026	coreceptor activity(GO:0015026)
0.2	0.5	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2	0.6	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1	1.8	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	0.6	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.6	GO:0004979	beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1	1.9	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	1.5	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	1.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.5	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.7	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	3.4	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.1	1.0	GO:0005534	galactose binding(GO:0005534)
0.1	0.9	GO:0070064	proline-rich region binding(GO:0070064)
0.1	3.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	2.2	GO:0043274	phospholipase binding(GO:0043274)
0.1	12.4	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	6.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.6	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	1.8	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	2.9	GO:0031489	myosin V binding(GO:0031489)
0.1	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.5	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.9	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.4	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.5	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.1	3.5	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.4	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.5	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.3	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	1.6	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.4	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1	0.8	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.8	GO:1990239	steroid hormone binding(GO:1990239)
0.1	0.7	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1	2.2	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.4	GO:0004974	leukotriene receptor activity(GO:0004974)
0.1	1.4	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.4	GO:0033265	choline binding(GO:0033265)
0.1	0.5	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.1	0.5	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1	0.7	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	9.0	GO:0017124	SH3 domain binding(GO:0017124)
0.1	0.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	1.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	2.9	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.6	GO:0043426	MRF binding(GO:0043426)
0.1	1.1	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.1	1.3	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.4	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	1.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.7	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.9	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	1.7	GO:0005521	lamin binding(GO:0005521)
0.1	3.0	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1	1.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.3	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	5.3	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	2.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	2.6	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	4.0	GO:0030295	protein kinase activator activity(GO:0030295)
0.1	1.1	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.6	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.2	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.1	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.3	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	0.6	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	1.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	1.7	GO:0017091	AU-rich element binding(GO:0017091)
0.1	6.5	GO:0019887	protein kinase regulator activity(GO:0019887)
0.1	1.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	1.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	2.9	GO:0019003	GDP binding(GO:0019003)
0.0	0.6	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	2.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.2	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	1.3	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	1.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	4.3	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.8	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.3	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.4	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.0	0.5	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	1.0	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.4	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	1.2	GO:0005504	fatty acid binding(GO:0005504)
0.0	1.0	GO:0019825	oxygen binding(GO:0019825)
0.0	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.5	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	1.1	GO:0030552	cAMP binding(GO:0030552)
0.0	1.0	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.9	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	3.1	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.6	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	6.3	GO:0003924	GTPase activity(GO:0003924)
0.0	0.2	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	1.2	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.2	GO:0097643	amylin receptor activity(GO:0097643)
0.0	0.3	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.3	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.9	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.6	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	1.1	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0	0.9	GO:0061733	histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.6	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.8	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0030305	heparanase activity(GO:0030305)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	3.2	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	26.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.9	25.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.7	16.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6	31.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.6	5.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	23.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5	39.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4	16.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.4	1.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.4	14.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.4	10.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	8.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.3	6.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.3	3.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	1.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	4.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	4.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	6.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2	3.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	3.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	1.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	2.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	4.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	5.0	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.2	3.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	0.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	4.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	1.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.9	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	13.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	6.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	14.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	2.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	5.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	2.6	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	1.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	4.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	0.6	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	1.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	1.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.9	REACTOME METABOLISM OF MRNA	Genes involved in Metabolism of mRNA
0.1	2.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.9	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	0.9	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	1.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.4	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	2.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.6	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	1.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	1.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	1.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.0	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.3	17.2	GO:0071461	cellular response to redox state(GO:0071461)
3.6	10.9	GO:0070666	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
3.6	14.5	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.5	19.9	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
2.4	11.9	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
2.1	12.4	GO:0000821	regulation of arginine metabolic process(GO:0000821)
1.9	7.7	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.8	12.4	GO:0033590	response to cobalamin(GO:0033590)
1.6	7.9	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
1.6	6.2	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
1.5	9.2	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
1.5	4.4	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.2	3.5	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
1.1	5.3	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.0	5.0	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.0	7.8	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.9	4.5	GO:2000630	positive regulation of hyaluronan biosynthetic process(GO:1900127) positive regulation of miRNA metabolic process(GO:2000630)
0.9	5.3	GO:0016554	cytidine to uridine editing(GO:0016554)
0.9	3.5	GO:0008063	Toll signaling pathway(GO:0008063)
0.9	11.4	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.8	3.2	GO:0010752	regulation of cGMP-mediated signaling(GO:0010752)
0.8	25.3	GO:0045730	respiratory burst(GO:0045730)
0.7	2.1	GO:0060178	regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.7	13.2	GO:0035855	megakaryocyte development(GO:0035855)
0.7	2.6	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.7	13.1	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.6	1.9	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.6	1.2	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6	4.7	GO:0043307	eosinophil activation(GO:0043307)
0.6	5.8	GO:0045059	positive thymic T cell selection(GO:0045059)
0.6	1.7	GO:0061056	sclerotome development(GO:0061056)
0.6	1.7	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.6	4.0	GO:0032596	protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.5	1.6	GO:2000439	positive regulation of monocyte extravasation(GO:2000439)
0.5	7.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.5	2.5	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.5	1.0	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.5	2.3	GO:0042631	cellular response to water deprivation(GO:0042631)
0.5	7.9	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.5	0.5	GO:0072425	signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.4	2.2	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
0.4	1.3	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4	6.7	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.4	1.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.4	1.2	GO:0008355	olfactory learning(GO:0008355)
0.4	0.4	GO:0050880	regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.4	1.9	GO:0046203	spermidine catabolic process(GO:0046203)
0.4	5.0	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.4	0.8	GO:0072683	T cell extravasation(GO:0072683)
0.4	5.7	GO:0015671	oxygen transport(GO:0015671)
0.4	0.4	GO:0035905	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.4	2.6	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4	1.1	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4	1.4	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.3	4.7	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.3	1.0	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.3	1.0	GO:0001300	chronological cell aging(GO:0001300)
0.3	1.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.3	1.3	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.3	8.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.3	1.0	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.3	1.3	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.3	25.6	GO:0042100	B cell proliferation(GO:0042100)
0.3	2.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.3	6.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.3	7.7	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.3	1.7	GO:0007296	vitellogenesis(GO:0007296)
0.3	1.4	GO:0034127	detection of lipopolysaccharide(GO:0032497) regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.3	0.8	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.3	1.1	GO:0030242	pexophagy(GO:0030242)
0.3	2.2	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.3	2.2	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.3	0.5	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3	1.9	GO:0001782	B cell homeostasis(GO:0001782)
0.3	3.1	GO:0048296	regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3	21.4	GO:0030183	B cell differentiation(GO:0030183)
0.3	2.0	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3	1.5	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.3	5.8	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.2	0.7	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.2	2.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	5.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2	1.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.2	1.0	GO:0021997	response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.2	2.4	GO:1904424	regulation of GTP binding(GO:1904424)
0.2	1.2	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2	1.2	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2	0.9	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.2	1.9	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.2	3.5	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2	0.7	GO:1990502	dense core granule maturation(GO:1990502)
0.2	5.0	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.2	1.1	GO:0035912	dorsal aorta morphogenesis(GO:0035912)
0.2	0.9	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2	4.8	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.2	0.9	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.2	0.6	GO:1903676	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2	0.6	GO:1904744	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
0.2	4.0	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2	0.6	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.2	7.0	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.2	1.1	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.2	1.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.2	1.3	GO:0006226	dUMP biosynthetic process(GO:0006226)
0.2	0.4	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.2	2.3	GO:0071285	cellular response to lithium ion(GO:0071285)
0.2	1.4	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.2	3.2	GO:0051014	actin filament severing(GO:0051014)
0.2	3.2	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.2	0.7	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.2	0.8	GO:1901029	adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2	1.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.2	1.4	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.2	0.6	GO:2000568	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2	1.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.1	3.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.6	GO:0072299	visceral serous pericardium development(GO:0061032) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1	0.6	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
0.1	7.9	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.1	0.6	GO:0061358	adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) negative regulation of Wnt protein secretion(GO:0061358)
0.1	0.6	GO:0019230	proprioception(GO:0019230)
0.1	1.1	GO:1903358	regulation of Golgi organization(GO:1903358)
0.1	0.5	GO:2000137	negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.1	0.9	GO:0072711	cellular response to hydroxyurea(GO:0072711)
0.1	0.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.4	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	1.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	1.5	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.8	GO:0031947	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.1	0.5	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	14.6	GO:0006903	vesicle targeting(GO:0006903)
0.1	0.7	GO:0060613	fat pad development(GO:0060613)
0.1	0.5	GO:1903896	positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1	0.3	GO:0009826	unidimensional cell growth(GO:0009826)
0.1	2.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.2	GO:1990262	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1	0.9	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1	0.6	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1	1.9	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	1.5	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.1	0.7	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	0.8	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.1	2.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	1.1	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.5	GO:0021759	globus pallidus development(GO:0021759)
0.1	15.4	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1	0.5	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1	0.7	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.4	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1	14.2	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1	0.3	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1	1.5	GO:0001780	neutrophil homeostasis(GO:0001780)
0.1	1.5	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	0.3	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1	0.3	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	1.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.1	0.4	GO:0071800	podosome assembly(GO:0071800)
0.1	0.7	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1	0.3	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1	0.7	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	1.7	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.6	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.1	0.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	3.0	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714)
0.1	1.9	GO:0010842	retina layer formation(GO:0010842)
0.1	1.0	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	1.1	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.2	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	0.4	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.1	0.9	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	1.0	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	1.4	GO:0071404	cellular response to lipoprotein particle stimulus(GO:0071402) cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.1	0.9	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.1	16.2	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.1	0.8	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.8	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1	1.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	1.9	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.1	0.9	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.1	0.6	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	1.9	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.4	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.1	1.2	GO:0016180	snRNA processing(GO:0016180)
0.1	1.0	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1	2.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	1.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	1.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.1	0.7	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.1	0.6	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.1	0.3	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.2	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1	5.6	GO:0007286	spermatid development(GO:0007286)
0.1	0.8	GO:0098751	bone cell development(GO:0098751)
0.1	0.8	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.1	1.6	GO:0045026	plasma membrane fusion(GO:0045026)
0.1	0.4	GO:1990592	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	0.3	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.6	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.3	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0	0.2	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.5	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.5	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	1.7	GO:0008542	visual learning(GO:0008542)
0.0	0.1	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.2	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.4	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
0.0	0.2	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.8	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.2	GO:2001138	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0	0.3	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.7	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.2	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.2	GO:0070170	regulation of tooth mineralization(GO:0070170)
0.0	0.3	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.3	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.0	0.9	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	1.1	GO:0006298	mismatch repair(GO:0006298)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.0	0.1	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.0	0.1	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.0	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.6	GO:0001502	cartilage condensation(GO:0001502)
0.0	1.4	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.8	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.9	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.4	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.7	GO:0090383	phagosome acidification(GO:0090383)
0.0	1.7	GO:0072431	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	0.1	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	0.5	GO:0060065	uterus development(GO:0060065)
0.0	0.9	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	1.2	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	3.0	GO:1990823	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.8	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.5	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.1	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.3	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.4	GO:0044849	estrous cycle(GO:0044849)
0.0	0.3	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0050729	positive regulation of inflammatory response(GO:0050729)
0.0	0.2	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.4	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.4	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.4	GO:0007173	epidermal growth factor receptor signaling pathway(GO:0007173)
0.0	0.5	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	2.0	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.3	GO:0060177	regulation of angiotensin levels in blood(GO:0002002) angiotensin maturation(GO:0002003) regulation of angiotensin metabolic process(GO:0060177)
0.0	1.0	GO:0006378	mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0	1.9	GO:0030218	erythrocyte differentiation(GO:0030218)
0.0	0.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.2	GO:0032754	positive regulation of interleukin-5 production(GO:0032754)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.4	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.2	GO:0035196	production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0	1.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.7	GO:0046039	GTP metabolic process(GO:0046039)
0.0	0.2	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.6	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.2	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.1	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.8	GO:0048477	oogenesis(GO:0048477)
0.0	0.5	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.5	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.0	GO:0007549	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.4	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.2	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
0.0	0.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.2	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.4	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.3	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	1.0	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.6	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.2	GO:0070997	neuron death(GO:0070997)
0.0	0.5	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.1	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.5	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.7	GO:0042113	B cell activation(GO:0042113)
0.0	0.2	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	1.0	GO:0060041	retina development in camera-type eye(GO:0060041)