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ENCODE cell lines, expression (Ernst 2011)

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Results for SPIC

Z-value: 2.33

Motif logo

Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
ENSG00000166211.6 SPIC

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_98031310 10.72 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr10_-_98031265 10.07 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr16_+_81812863 7.03 ENST00000359376.3
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_-_160681593 6.53 ENST00000368045.3
ENST00000368046.3
CD48
CD48 molecule
chr13_-_46756351 6.38 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_25205666 6.03 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr22_+_23247030 6.02 ENST00000390324.2
IGLJ3
immunoglobulin lambda joining 3
chr12_+_25205568 5.94 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr6_-_32557610 5.83 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr3_-_121379739 5.56 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr16_+_30194916 5.55 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr14_-_23285011 5.41 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr10_+_97471508 4.99 ENST00000453258.2
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr19_+_42381337 4.93 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr17_-_29641104 4.90 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr14_-_23285069 4.84 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr3_+_16926441 4.84 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr1_+_111415757 4.84 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr1_-_25256368 4.66 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr12_-_15114492 4.50 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_-_15114603 4.47 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr19_-_39108568 4.41 ENST00000586296.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr12_+_54892550 4.36 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr2_+_33701286 4.34 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_31230650 4.31 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr2_+_143886877 4.25 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15
chr15_-_80263506 4.21 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chrX_+_78200913 4.21 ENST00000171757.2
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chrX_+_78200829 4.12 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr17_-_29641084 4.11 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr17_+_72462525 4.06 ENST00000360141.3
CD300A
CD300a molecule
chr21_-_15918618 4.01 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_-_183560011 3.90 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr12_+_7055767 3.75 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_-_9129735 3.69 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_+_49838653 3.66 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr12_+_7055631 3.53 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_+_72462766 3.41 ENST00000392625.3
ENST00000361933.3
ENST00000310828.5
CD300A
CD300a molecule
chr14_+_88471468 3.41 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr7_-_150329421 3.36 ENST00000493969.1
ENST00000328902.5
GIMAP6
GTPase, IMAP family member 6
chr6_+_14117872 3.29 ENST00000379153.3
CD83
CD83 molecule
chr22_+_37309662 3.28 ENST00000403662.3
ENST00000262825.5
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_9129598 3.26 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_+_161632937 3.20 ENST00000236937.9
ENST00000367961.4
ENST00000358671.5
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr17_-_20370847 3.16 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr6_+_391739 3.14 ENST00000380956.4
IRF4
interferon regulatory factor 4
chr19_-_39108552 3.12 ENST00000591517.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr13_+_31309645 3.09 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr6_-_154677900 3.08 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr17_+_34431212 3.02 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr22_+_37257015 2.96 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
NCF4
neutrophil cytosolic factor 4, 40kDa
chr1_-_9129895 2.92 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_150738261 2.90 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr19_-_39108643 2.84 ENST00000396857.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr6_-_90121789 2.81 ENST00000359203.3
RRAGD
Ras-related GTP binding D
chr17_-_34524157 2.77 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr18_-_53253323 2.76 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr1_-_9129631 2.75 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_+_25205446 2.72 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr11_+_102188272 2.70 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr1_-_183559693 2.65 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr19_-_10446449 2.63 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr19_-_39826639 2.57 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr7_+_74188309 2.57 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr10_-_121302195 2.54 ENST00000369103.2
RGS10
regulator of G-protein signaling 10
chr12_+_54891495 2.53 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr19_-_7766991 2.52 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr17_-_34625719 2.51 ENST00000422211.2
ENST00000542124.1
CCL3L1
chemokine (C-C motif) ligand 3-like 1
chr18_-_53253112 2.49 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr8_+_11351494 2.42 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr22_+_18593446 2.36 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr1_+_150245177 2.35 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr1_+_192544857 2.26 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chr2_+_182321925 2.24 ENST00000339307.4
ENST00000397033.2
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_+_158985457 2.23 ENST00000567661.1
ENST00000474473.1
IFI16
interferon, gamma-inducible protein 16
chr19_-_10450328 2.23 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr2_+_68592305 2.20 ENST00000234313.7
PLEK
pleckstrin
chr3_+_121796697 2.17 ENST00000482356.1
ENST00000393627.2
CD86
CD86 molecule
chr11_-_615570 2.16 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr11_+_22688150 2.15 ENST00000454584.2
GAS2
growth arrest-specific 2
chr19_+_6772710 2.13 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1
vav 1 guanine nucleotide exchange factor
chr20_-_4795747 2.12 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr4_+_68424434 2.11 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr12_+_7060432 2.06 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_-_10450287 2.04 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr6_+_106534192 2.02 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr11_-_60719213 2.00 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chrX_-_70838306 1.99 ENST00000373691.4
ENST00000373693.3
CXCR3
chemokine (C-X-C motif) receptor 3
chr6_+_31582961 1.98 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr17_-_34417479 1.95 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr19_-_36233332 1.90 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr19_-_6481776 1.87 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr14_-_106518922 1.86 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr11_+_1874200 1.85 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr14_+_65878565 1.85 ENST00000556518.1
ENST00000557164.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr17_+_67498538 1.84 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr19_-_9731872 1.83 ENST00000424629.1
ENST00000326044.5
ENST00000354661.4
ENST00000435550.1
ENST00000444611.1
ENST00000421525.1
ZNF561
zinc finger protein 561
chr11_-_615942 1.83 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr21_-_46340884 1.78 ENST00000302347.5
ENST00000517819.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr16_-_88717482 1.77 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr10_+_35416090 1.76 ENST00000354759.3
CREM
cAMP responsive element modulator
chr3_+_178525080 1.75 ENST00000358316.3
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr1_+_241695424 1.72 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr11_+_7618413 1.70 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_+_161551101 1.67 ENST00000367962.4
ENST00000367960.5
ENST00000403078.3
ENST00000428605.2
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr21_-_46340770 1.65 ENST00000397854.3
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chrX_+_24072833 1.65 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_150245099 1.60 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr2_+_102972363 1.57 ENST00000409599.1
IL18R1
interleukin 18 receptor 1
chr5_-_150603679 1.57 ENST00000355417.2
CCDC69
coiled-coil domain containing 69
chr2_-_163175133 1.56 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr11_-_57194550 1.56 ENST00000528187.1
ENST00000524863.1
ENST00000533051.1
ENST00000529494.1
ENST00000395124.1
ENST00000533524.1
ENST00000533245.1
ENST00000530316.1
SLC43A3
solute carrier family 43, member 3
chr6_-_133079022 1.55 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr17_+_18380051 1.52 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr15_+_75335604 1.50 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr2_-_152146385 1.50 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr7_+_150264365 1.47 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr2_+_201981527 1.45 ENST00000441224.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr16_-_88717423 1.44 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr2_-_231084820 1.42 ENST00000258382.5
ENST00000338556.3
SP110
SP110 nuclear body protein
chr19_+_41903709 1.37 ENST00000542943.1
ENST00000457836.2
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr11_+_5710919 1.36 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr2_-_231084617 1.34 ENST00000409815.2
SP110
SP110 nuclear body protein
chr1_-_160549235 1.34 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr8_-_79717750 1.33 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr19_-_8642289 1.33 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr11_+_7626950 1.29 ENST00000530181.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr6_+_116601265 1.29 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr14_-_89883412 1.27 ENST00000557258.1
FOXN3
forkhead box N3
chr6_+_46097711 1.27 ENST00000321037.4
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr3_+_5229356 1.27 ENST00000256497.4
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chrX_-_107018969 1.24 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr2_+_64751433 1.23 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH
aftiphilin
chr19_-_51875894 1.23 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr2_-_231084659 1.22 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr12_+_12878829 1.19 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr12_+_53693466 1.18 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr13_+_43148281 1.16 ENST00000239849.6
ENST00000398795.2
ENST00000544862.1
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr2_+_62423242 1.13 ENST00000301998.4
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr3_-_4793274 1.13 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr9_-_5304432 1.12 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr19_-_19754404 1.10 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chr10_-_27149904 1.07 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
ABI1
abl-interactor 1
chr6_-_27114577 1.05 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr12_+_10658489 1.05 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr18_+_21033239 1.05 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chr3_+_151986709 1.04 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr16_+_31271274 1.03 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr1_-_22109682 1.02 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chrX_-_100604184 1.02 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr21_+_34638656 1.00 ENST00000290200.2
IL10RB
interleukin 10 receptor, beta
chr10_+_112257596 0.99 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr17_-_37934466 0.99 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr5_-_142780280 0.98 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_+_149230680 0.96 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr18_-_52989525 0.95 ENST00000457482.3
TCF4
transcription factor 4
chr1_+_212208919 0.92 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_+_201981119 0.92 ENST00000395148.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_-_17783990 0.91 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5
TBC1 domain family, member 5
chr12_+_120105558 0.91 ENST00000229328.5
ENST00000541640.1
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr19_-_41903161 0.89 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr12_+_6602517 0.89 ENST00000315579.5
ENST00000539714.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr2_+_89998789 0.86 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr12_+_111843749 0.86 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr19_+_55128576 0.85 ENST00000396331.1
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr16_-_87799505 0.85 ENST00000353170.5
ENST00000561825.1
ENST00000270583.5
ENST00000562261.1
ENST00000347925.5
KLHDC4
kelch domain containing 4
chr20_+_43595115 0.85 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
STK4
serine/threonine kinase 4
chr16_+_23652773 0.84 ENST00000563998.1
ENST00000568589.1
ENST00000568272.1
DCTN5
dynactin 5 (p25)
chr2_+_61108771 0.84 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_+_181057638 0.84 ENST00000367577.4
IER5
immediate early response 5
chr18_-_52989217 0.83 ENST00000570287.2
TCF4
transcription factor 4
chr5_+_102455853 0.82 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr8_-_77912431 0.81 ENST00000357039.4
ENST00000522527.1
PEX2
peroxisomal biogenesis factor 2
chrX_+_55478538 0.81 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr7_-_99698338 0.81 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr15_+_89787180 0.80 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI
Fanconi anemia, complementation group I
chr1_+_14075865 0.79 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr14_+_57735614 0.79 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr14_+_76618242 0.79 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
GPATCH2L
G patch domain containing 2-like
chr19_+_55141861 0.78 ENST00000396327.3
ENST00000324602.7
ENST00000434867.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr11_-_67120974 0.77 ENST00000539074.1
ENST00000312419.3
POLD4
polymerase (DNA-directed), delta 4, accessory subunit
chr11_-_22647350 0.77 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr2_+_89999259 0.77 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr3_+_23847394 0.76 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr5_-_142782862 0.76 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_73668692 0.74 ENST00000352131.3
ENST00000055077.3
RFC2
replication factor C (activator 1) 2, 40kDa
chr10_-_27149851 0.73 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
ABI1
abl-interactor 1
chr1_-_211848899 0.73 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr12_-_44152551 0.73 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chrX_-_47489244 0.71 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr7_+_108210012 0.71 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr19_+_55141948 0.70 ENST00000396332.4
ENST00000427581.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr8_-_42623747 0.70 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr5_-_130970723 0.70 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr17_+_42422662 0.69 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr19_+_7069426 0.68 ENST00000252840.6
ENST00000414706.1
ZNF557
zinc finger protein 557
chr10_-_27149792 0.68 ENST00000376140.3
ENST00000376170.4
ABI1
abl-interactor 1
chr5_+_162864575 0.68 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr12_-_49351228 0.67 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr3_-_176914238 0.66 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.4 37.7 PID BCR 5PATHWAY BCR signaling pathway
0.3 3.3 PID IL5 PATHWAY IL5-mediated signaling events
0.2 9.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 16.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 3.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 10.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 9.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 4.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 4.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 11.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 3.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.3 PID EPO PATHWAY EPO signaling pathway
0.1 1.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 7.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 4.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 12.6 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
1.7 12.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.2 4.9 GO:0019770 IgG receptor activity(GO:0019770)
1.2 3.6 GO:0004914 interleukin-5 receptor activity(GO:0004914)
1.1 21.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
1.0 2.9 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.9 10.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.9 9.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 4.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.7 2.0 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.6 1.9 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.6 2.3 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.6 10.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 7.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.6 1.7 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.5 7.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 3.4 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.5 1.4 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.5 2.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 1.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 22.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 7.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.4 1.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.4 5.0 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.3 5.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 1.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 2.5 GO:0019863 IgE binding(GO:0019863)
0.3 1.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 2.2 GO:1990405 protein antigen binding(GO:1990405)
0.3 1.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 0.7 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.2 4.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 4.8 GO:0051400 BH domain binding(GO:0051400)
0.2 1.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 2.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 4.4 GO:0050811 GABA receptor binding(GO:0050811)
0.2 6.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 1.8 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 4.9 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.2 2.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 1.0 GO:0001851 complement component C3b binding(GO:0001851)
0.2 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.6 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 1.2 GO:0043426 MRF binding(GO:0043426)
0.1 4.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.8 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 1.3 GO:0089720 caspase binding(GO:0089720)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 2.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 2.9 GO:0043236 laminin binding(GO:0043236)
0.1 9.0 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 4.5 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 2.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.1 1.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.6 GO:0005123 death receptor binding(GO:0005123)
0.1 0.3 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.1 2.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.3 GO:0042166 acetylcholine binding(GO:0042166)
0.1 0.6 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 3.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 3.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 4.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0001047 core promoter binding(GO:0001047)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 2.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.0 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.4 GO:0032010 phagolysosome(GO:0032010)
0.9 4.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.8 9.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.7 4.9 GO:0019815 B cell receptor complex(GO:0019815)
0.7 9.6 GO:0031209 SCAR complex(GO:0031209)
0.7 13.7 GO:0001891 phagocytic cup(GO:0001891)
0.6 1.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.6 2.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.5 2.8 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 4.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 0.3 GO:0034709 methylosome(GO:0034709)
0.3 5.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 1.0 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.2 1.7 GO:0036021 endolysosome lumen(GO:0036021)
0.2 3.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.9 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 3.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.9 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 0.9 GO:0031673 H zone(GO:0031673)
0.2 0.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.5 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 1.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 12.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.2 1.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 8.1 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 0.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 7.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 10.4 GO:0035579 specific granule membrane(GO:0035579)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.6 GO:0097342 ripoptosome(GO:0097342)
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.1 0.5 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.1 1.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 1.2 GO:0051233 spindle midzone(GO:0051233)
0.1 0.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 8.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 5.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 7.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.5 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 9.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 8.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 2.9 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0005797 Golgi trans cisterna(GO:0000138) Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.5 GO:0043679 axon terminus(GO:0043679)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 6.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.0 GO:1990393 3M complex(GO:1990393)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0070069 cytochrome complex(GO:0070069)
0.0 3.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.0 GO:0005874 microtubule(GO:0005874)
0.0 1.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 14.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.4 GO:0035578 azurophil granule lumen(GO:0035578)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 35.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6 12.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.6 7.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.4 7.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.3 5.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 2.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 5.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 12.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 9.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 16.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 2.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 1.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 8.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 8.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 3.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.9 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 2.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 13.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 2.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 1.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 4.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 2.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 11.9 GO:0002316 follicular B cell differentiation(GO:0002316)
2.7 21.7 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
2.2 9.0 GO:0071461 cellular response to redox state(GO:0071461)
1.8 12.6 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.8 5.3 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
1.7 6.9 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
1.7 10.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
1.4 5.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
1.3 4.0 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.2 3.6 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
1.2 5.8 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.7 5.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.7 2.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.6 3.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.6 1.9 GO:0036071 N-glycan fucosylation(GO:0036071)
0.6 1.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.6 2.3 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.6 2.2 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5 2.5 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.5 1.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.5 10.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 5.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.5 2.8 GO:0071233 cellular response to leucine(GO:0071233)
0.4 3.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.4 2.0 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.4 2.0 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.4 2.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 1.6 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.4 7.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.4 1.2 GO:0100009 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.4 1.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.4 2.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.4 6.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 1.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 1.3 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.3 1.7 GO:0046203 spermidine catabolic process(GO:0046203)
0.3 10.6 GO:0045730 respiratory burst(GO:0045730)
0.3 2.9 GO:2001300 lipoxin metabolic process(GO:2001300)
0.3 1.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.3 5.0 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.3 0.9 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 2.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.3 1.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.3 1.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 0.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 2.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 5.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 1.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.7 GO:0006404 RNA import into nucleus(GO:0006404)
0.2 1.3 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 4.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 2.9 GO:0015671 oxygen transport(GO:0015671)
0.2 27.3 GO:0030183 B cell differentiation(GO:0030183)
0.2 2.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 2.0 GO:0010818 T cell chemotaxis(GO:0010818)
0.2 0.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 0.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 1.2 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.6 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.2 3.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 0.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 1.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 2.7 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.2 1.0 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2 1.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 3.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 0.6 GO:0019086 late viral transcription(GO:0019086)
0.1 0.6 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.7 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 2.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 2.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.4 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 4.1 GO:0010447 response to acidic pH(GO:0010447)
0.1 1.2 GO:0006477 protein sulfation(GO:0006477)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1 1.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 2.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.6 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 1.0 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 14.4 GO:0007338 single fertilization(GO:0007338)
0.1 1.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 2.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1 0.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.7 GO:0097242 beta-amyloid clearance(GO:0097242)
0.1 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.8 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.7 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.8 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) regulation of receptor catabolic process(GO:2000644)
0.1 0.3 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.2 GO:0090155 glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 1.3 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.2 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.7 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 0.5 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.2 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 2.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0051601 exocyst localization(GO:0051601)
0.1 1.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 1.3 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 0.2 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.3 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.2 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 2.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.7 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 1.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.6 GO:0019985 translesion synthesis(GO:0019985)
0.0 4.8 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.1 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.0 0.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 1.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.4 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.9 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.5 GO:0032098 regulation of appetite(GO:0032098)
0.0 1.5 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.3 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.8 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.0 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.5 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0097421 liver regeneration(GO:0097421)
0.0 2.5 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 2.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.0 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.5 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)