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ENCODE cell lines, expression (Ernst 2011)

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Results for STAT1_STAT3_BCL6

Z-value: 2.17

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
STAT1
ENSG00000115415.14 STAT1
STAT3
ENSG00000168610.10 STAT3
BCL6
ENSG00000113916.13 BCL6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT1hg19_v2_chr2_-_191885686_191885750-0.683.9e-03Click!
STAT3hg19_v2_chr17_-_40540484_40540537-0.449.1e-02Click!
BCL6hg19_v2_chr3_-_187454281_1874543570.224.2e-01Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_102668879 8.42 ENST00000315274.6
 MMP1
 matrix metallopeptidase 1 (interstitial collagenase)
chr8_-_27469196 7.30 ENST00000546343.1
ENST00000560566.1
 CLU
 clusterin
chr7_+_134464414 7.11 ENST00000361901.2
 CALD1
 caldesmon 1
chr1_-_68299130 6.87 ENST00000370982.3
 GNG12
 guanine nucleotide binding protein (G protein), gamma 12
chr3_-_93692781 6.34 ENST00000394236.3
 PROS1
 protein S (alpha)
chr17_+_32582293 6.25 ENST00000580907.1
ENST00000225831.4
 CCL2
 chemokine (C-C motif) ligand 2
chr9_-_117880477 6.13 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
 TNC
 tenascin C
chr8_-_27468842 6.08 ENST00000523500.1
 CLU
 clusterin
chr7_+_134464376 5.68 ENST00000454108.1
ENST00000361675.2
 CALD1
 caldesmon 1
chr8_-_27468945 5.38 ENST00000405140.3
 CLU
 clusterin
chr2_-_190044480 5.21 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr3_-_149095652 4.74 ENST00000305366.3
 TM4SF1
 transmembrane 4 L six family member 1
chr14_-_30396948 4.42 ENST00000331968.5
 PRKD1
 protein kinase D1
chr10_-_33625154 3.48 ENST00000265371.4
 NRP1
 neuropilin 1
chr12_+_53443963 3.27 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chrX_-_48931648 3.14 ENST00000376386.3
ENST00000376390.4
 PRAF2
 PRA1 domain family, member 2
chr12_-_91539918 3.09 ENST00000548218.1
 DCN
 decorin
chr15_-_60690932 3.06 ENST00000559818.1
 ANXA2
 annexin A2
chr12_+_53443680 3.05 ENST00000314250.6
ENST00000451358.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chrX_-_10544942 3.02 ENST00000380779.1
 MID1
 midline 1 (Opitz/BBB syndrome)
chr2_-_106013400 2.77 ENST00000409807.1
 FHL2
 four and a half LIM domains 2
chr1_+_163038565 2.67 ENST00000421743.2
 RGS4
 regulator of G-protein signaling 4
chr9_-_117853297 2.52 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
 TNC
 tenascin C
chr11_+_844067 2.50 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
 TSPAN4
 tetraspanin 4
chr10_-_90751038 2.48 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
 ACTA2
 actin, alpha 2, smooth muscle, aorta
chr16_-_10652993 2.44 ENST00000536829.1
 EMP2
 epithelial membrane protein 2
chr1_+_163039143 2.42 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
 RGS4
 regulator of G-protein signaling 4
chr6_+_151561085 2.34 ENST00000402676.2
 AKAP12
 A kinase (PRKA) anchor protein 12
chr1_-_150780757 2.29 ENST00000271651.3
 CTSK
 cathepsin K
chr3_-_123512688 2.27 ENST00000475616.1
 MYLK
 myosin light chain kinase
chr15_+_63340647 2.25 ENST00000404484.4
 TPM1
 tropomyosin 1 (alpha)
chr12_+_93964746 2.16 ENST00000536696.2
 SOCS2
 suppressor of cytokine signaling 2
chr19_+_15218180 2.09 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
 SYDE1
 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_-_146781153 2.00 ENST00000520473.1
 DPYSL3
 dihydropyrimidinase-like 3
chr11_+_123986069 1.99 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
 VWA5A
 von Willebrand factor A domain containing 5A
chr12_+_102271129 1.99 ENST00000258534.8
 DRAM1
 DNA-damage regulated autophagy modulator 1
chr5_-_42812143 1.89 ENST00000514985.1
 SEPP1
 selenoprotein P, plasma, 1
chr9_-_75567962 1.81 ENST00000297785.3
ENST00000376939.1
 ALDH1A1
 aldehyde dehydrogenase 1 family, member A1
chr8_+_30300119 1.77 ENST00000520191.1
 RBPMS
 RNA binding protein with multiple splicing
chr1_-_154946825 1.76 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
 SHC1
 SHC (Src homology 2 domain containing) transforming protein 1
chr15_+_63340734 1.64 ENST00000560959.1
 TPM1
 tropomyosin 1 (alpha)
chr1_-_230850043 1.63 ENST00000366667.4
 AGT
 angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_45067659 1.62 ENST00000296130.4
 CLEC3B
 C-type lectin domain family 3, member B
chr3_+_62304712 1.62 ENST00000494481.1
 C3orf14
 chromosome 3 open reading frame 14
chr8_-_18666360 1.59 ENST00000286485.8
 PSD3
 pleckstrin and Sec7 domain containing 3
chr17_-_1619535 1.58 ENST00000573075.1
ENST00000574306.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chr5_-_111092873 1.57 ENST00000509025.1
ENST00000515855.1
 NREP
 neuronal regeneration related protein
chr3_+_62304648 1.54 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
 C3orf14
 chromosome 3 open reading frame 14
chr8_-_11710979 1.54 ENST00000415599.2
 CTSB
 cathepsin B
chr2_-_128399706 1.52 ENST00000426981.1
 LIMS2
 LIM and senescent cell antigen-like domains 2
chr5_-_122372354 1.52 ENST00000306442.4
 PPIC
 peptidylprolyl isomerase C (cyclophilin C)
chr3_-_185538849 1.52 ENST00000421047.2
 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
chr12_-_133050726 1.45 ENST00000595994.1
 MUC8
 mucin 8
chr17_-_1619491 1.44 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
 MIR22HG
 MIR22 host gene (non-protein coding)
chr1_-_144994909 1.42 ENST00000369347.4
ENST00000369354.3
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr6_-_52859046 1.41 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
 GSTA4
 glutathione S-transferase alpha 4
chr15_+_63340775 1.39 ENST00000559281.1
ENST00000317516.7
 TPM1
 tropomyosin 1 (alpha)
chr12_-_7261772 1.36 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
 C1RL
 complement component 1, r subcomponent-like
chr1_+_221051699 1.36 ENST00000366903.6
 HLX
 H2.0-like homeobox
chr22_+_33197683 1.35 ENST00000266085.6
 TIMP3
 TIMP metallopeptidase inhibitor 3
chr2_-_167232484 1.35 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
 SCN9A
 sodium channel, voltage-gated, type IX, alpha subunit
chr1_-_144995002 1.34 ENST00000369356.4
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr11_+_844406 1.33 ENST00000397404.1
 TSPAN4
 tetraspanin 4
chr4_+_169418195 1.31 ENST00000261509.6
ENST00000335742.7
 PALLD
 palladin, cytoskeletal associated protein
chr3_+_136537911 1.30 ENST00000393079.3
 SLC35G2
 solute carrier family 35, member G2
chr15_-_60690163 1.28 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
 ANXA2
 annexin A2
chr1_+_223900034 1.28 ENST00000295006.5
 CAPN2
 calpain 2, (m/II) large subunit
chr1_-_31845914 1.26 ENST00000373713.2
 FABP3
 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr14_-_92414055 1.26 ENST00000342058.4
 FBLN5
 fibulin 5
chr16_+_69221028 1.24 ENST00000336278.4
 SNTB2
 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr11_+_57365150 1.24 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
 SERPING1
 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr3_+_136537816 1.23 ENST00000446465.2
 SLC35G2
 solute carrier family 35, member G2
chr4_-_140005341 1.17 ENST00000379549.2
ENST00000512627.1
 ELF2
 E74-like factor 2 (ets domain transcription factor)
chr5_-_121413974 1.17 ENST00000231004.4
 LOX
 lysyl oxidase
chr6_+_30130969 1.15 ENST00000376694.4
 TRIM15
 tripartite motif containing 15
chr12_-_56120838 1.15 ENST00000548160.1
 CD63
 CD63 molecule
chr22_+_38609538 1.13 ENST00000407965.1
 MAFF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr4_-_140005443 1.13 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
 ELF2
 E74-like factor 2 (ets domain transcription factor)
chr12_-_120687948 1.11 ENST00000458477.2
 PXN
 paxillin
chr8_+_71485681 1.11 ENST00000391684.1
 AC120194.1
 AC120194.1
chr12_-_56120865 1.09 ENST00000548898.1
ENST00000552067.1
 CD63
 CD63 molecule
chr1_-_94374946 1.09 ENST00000370238.3
 GCLM
 glutamate-cysteine ligase, modifier subunit
chr14_-_21270995 1.07 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
 RNASE1
 ribonuclease, RNase A family, 1 (pancreatic)
chr1_+_154300217 1.07 ENST00000368489.3
 ATP8B2
 ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr22_-_36357671 1.05 ENST00000408983.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_+_102631248 1.03 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr14_+_94577074 1.01 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
 IFI27
 interferon, alpha-inducible protein 27
chr17_-_76975925 1.00 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
 LGALS3BP
 lectin, galactoside-binding, soluble, 3 binding protein
chr1_-_144994840 1.00 ENST00000369351.3
ENST00000369349.3
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr14_+_22458631 0.99 ENST00000390444.1
 TRAV16
 T cell receptor alpha variable 16
chr17_+_6347729 0.98 ENST00000572447.1
 FAM64A
 family with sequence similarity 64, member A
chr3_+_46283916 0.98 ENST00000395940.2
 CCR3
 chemokine (C-C motif) receptor 3
chr1_-_203155868 0.98 ENST00000255409.3
 CHI3L1
 chitinase 3-like 1 (cartilage glycoprotein-39)
chr5_-_111093081 0.97 ENST00000453526.2
ENST00000509427.1
 NREP
 neuronal regeneration related protein
chr1_-_201476274 0.96 ENST00000340006.2
 CSRP1
 cysteine and glycine-rich protein 1
chrX_+_106045891 0.95 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
 TBC1D8B
 TBC1 domain family, member 8B (with GRAM domain)
chr3_+_46283863 0.94 ENST00000545097.1
ENST00000541018.1
 CCR3
 chemokine (C-C motif) receptor 3
chr9_+_124088860 0.94 ENST00000373806.1
 GSN
 gelsolin
chr14_-_21270561 0.93 ENST00000412779.2
 RNASE1
 ribonuclease, RNase A family, 1 (pancreatic)
chr5_-_111092930 0.92 ENST00000257435.7
 NREP
 neuronal regeneration related protein
chr4_+_166300084 0.91 ENST00000402744.4
 CPE
 carboxypeptidase E
chr9_-_89562104 0.90 ENST00000298743.7
 GAS1
 growth arrest-specific 1
chr19_-_40324255 0.89 ENST00000593685.1
ENST00000600611.1
 DYRK1B
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr5_+_148521381 0.89 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr1_-_144995074 0.89 ENST00000534536.1
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr17_+_35851570 0.88 ENST00000394386.1
 DUSP14
 dual specificity phosphatase 14
chr6_+_108977520 0.88 ENST00000540898.1
 FOXO3
 forkhead box O3
chr1_+_162602244 0.87 ENST00000367922.3
ENST00000367921.3
 DDR2
 discoidin domain receptor tyrosine kinase 2
chr4_+_126237554 0.86 ENST00000394329.3
 FAT4
 FAT atypical cadherin 4
chr8_-_120651020 0.86 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_+_86396265 0.86 ENST00000395184.1
 ARHGAP24
 Rho GTPase activating protein 24
chr22_+_38597889 0.84 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
 MAFF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr17_-_1359443 0.82 ENST00000574295.1
ENST00000398970.5
ENST00000300574.2
 CRK
 v-crk avian sarcoma virus CT10 oncogene homolog
chr17_+_6347761 0.82 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
 FAM64A
 family with sequence similarity 64, member A
chr5_-_111093167 0.82 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr11_+_46740730 0.82 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
 F2
 coagulation factor II (thrombin)
chr22_-_27620603 0.81 ENST00000418271.1
ENST00000444114.1
 RP5-1172A22.1
 RP5-1172A22.1
chr6_-_131321863 0.80 ENST00000528282.1
 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
chr4_+_41258786 0.78 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr7_+_128399002 0.77 ENST00000493278.1
 CALU
 calumenin
chr5_-_111093406 0.75 ENST00000379671.3
 NREP
 neuronal regeneration related protein
chr4_+_169418255 0.75 ENST00000505667.1
ENST00000511948.1
 PALLD
 palladin, cytoskeletal associated protein
chr11_-_111782696 0.74 ENST00000227251.3
ENST00000526180.1
 CRYAB
 crystallin, alpha B
chr2_+_17935119 0.74 ENST00000317402.7
 GEN1
 GEN1 Holliday junction 5' flap endonuclease
chr7_+_98923505 0.74 ENST00000432884.2
ENST00000262942.5
 ARPC1A
 actin related protein 2/3 complex, subunit 1A, 41kDa
chr1_+_207262881 0.74 ENST00000451804.2
 C4BPB
 complement component 4 binding protein, beta
chr12_-_56121580 0.73 ENST00000550776.1
 CD63
 CD63 molecule
chr4_-_110723134 0.73 ENST00000510800.1
ENST00000512148.1
 CFI
 complement factor I
chr12_-_56121612 0.73 ENST00000546939.1
 CD63
 CD63 molecule
chr4_+_8594477 0.73 ENST00000315782.6
 CPZ
 carboxypeptidase Z
chr1_+_207262578 0.71 ENST00000243611.5
ENST00000367076.3
 C4BPB
 complement component 4 binding protein, beta
chr5_-_111093340 0.71 ENST00000508870.1
 NREP
 neuronal regeneration related protein
chr6_-_46889694 0.71 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
 GPR116
 G protein-coupled receptor 116
chr3_+_135741576 0.71 ENST00000334546.2
 PPP2R3A
 protein phosphatase 2, regulatory subunit B'', alpha
chr1_+_207262627 0.70 ENST00000391923.1
 C4BPB
 complement component 4 binding protein, beta
chr1_+_155099927 0.70 ENST00000368407.3
 EFNA1
 ephrin-A1
chr1_+_17906970 0.70 ENST00000375415.1
 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
chr20_+_44036900 0.68 ENST00000443296.1
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_110723335 0.67 ENST00000394634.2
 CFI
 complement factor I
chr2_-_183291741 0.67 ENST00000351439.5
ENST00000409365.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr5_-_179499108 0.66 ENST00000521389.1
 RNF130
 ring finger protein 130
chr2_+_17935383 0.66 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
 GEN1
 GEN1 Holliday junction 5' flap endonuclease
chr4_-_110723194 0.66 ENST00000394635.3
 CFI
 complement factor I
chr4_-_155533787 0.66 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
 FGG
 fibrinogen gamma chain
chrY_+_16634483 0.66 ENST00000382872.1
 NLGN4Y
 neuroligin 4, Y-linked
chr16_-_89785777 0.64 ENST00000561976.1
 VPS9D1
 VPS9 domain containing 1
chr3_-_148939835 0.64 ENST00000264613.6
 CP
 ceruloplasmin (ferroxidase)
chr17_+_48624450 0.63 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
 SPATA20
 spermatogenesis associated 20
chr1_+_6845384 0.62 ENST00000303635.7
 CAMTA1
 calmodulin binding transcription activator 1
chr7_+_76026832 0.62 ENST00000336517.4
 ZP3
 zona pellucida glycoprotein 3 (sperm receptor)
chr6_-_43484718 0.61 ENST00000372422.2
 YIPF3
 Yip1 domain family, member 3
chr7_-_74267836 0.61 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
 GTF2IRD2
 GTF2I repeat domain containing 2
chr1_-_8000872 0.60 ENST00000377507.3
 TNFRSF9
 tumor necrosis factor receptor superfamily, member 9
chrX_+_129473916 0.60 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
 SLC25A14
 solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_+_207262540 0.59 ENST00000452902.2
 C4BPB
 complement component 4 binding protein, beta
chrX_-_102941596 0.59 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
 MORF4L2
 mortality factor 4 like 2
chr6_-_83903600 0.59 ENST00000506587.1
ENST00000507554.1
 PGM3
 phosphoglucomutase 3
chr1_+_84609944 0.58 ENST00000370685.3
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr5_-_132113083 0.58 ENST00000296873.7
 SEPT8
 septin 8
chr5_-_140013275 0.58 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
 CD14
 CD14 molecule
chr1_-_173020056 0.57 ENST00000239468.2
ENST00000404377.3
 TNFSF18
 tumor necrosis factor (ligand) superfamily, member 18
chr3_-_114866084 0.57 ENST00000357258.3
 ZBTB20
 zinc finger and BTB domain containing 20
chr2_+_242255297 0.57 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
 SEPT2
 septin 2
chr5_-_132113036 0.56 ENST00000378706.1
 SEPT8
 septin 8
chr17_+_77021702 0.56 ENST00000392445.2
ENST00000354124.3
 C1QTNF1
 C1q and tumor necrosis factor related protein 1
chr3_+_183894566 0.55 ENST00000439647.1
 AP2M1
 adaptor-related protein complex 2, mu 1 subunit
chr6_-_122792919 0.54 ENST00000339697.4
 SERINC1
 serine incorporator 1
chr7_-_38671098 0.54 ENST00000356264.2
 AMPH
 amphiphysin
chr5_-_132112907 0.54 ENST00000458488.2
 SEPT8
 septin 8
chr5_-_132112921 0.53 ENST00000378721.4
ENST00000378701.1
 SEPT8
 septin 8
chr6_-_43484621 0.53 ENST00000506469.1
ENST00000503972.1
 YIPF3
 Yip1 domain family, member 3
chr12_+_13197218 0.53 ENST00000197268.8
 KIAA1467
 KIAA1467
chr22_+_20748405 0.52 ENST00000400451.2
ENST00000403682.3
ENST00000357502.5
 ZNF74
 zinc finger protein 74
chr7_+_74508372 0.52 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
 GTF2IRD2B
 GTF2I repeat domain containing 2B
chr14_+_62229075 0.51 ENST00000216294.4
 SNAPC1
 small nuclear RNA activating complex, polypeptide 1, 43kDa
chr7_-_38670957 0.49 ENST00000325590.5
ENST00000428293.2
 AMPH
 amphiphysin
chr2_+_242254679 0.48 ENST00000428282.1
ENST00000360051.3
 SEPT2
 septin 2
chr11_-_111782484 0.48 ENST00000533971.1
 CRYAB
 crystallin, alpha B
chr1_+_207262170 0.48 ENST00000367078.3
 C4BPB
 complement component 4 binding protein, beta
chr8_-_6420930 0.48 ENST00000325203.5
 ANGPT2
 angiopoietin 2
chr7_-_108096765 0.48 ENST00000379024.4
ENST00000351718.4
 NRCAM
 neuronal cell adhesion molecule
chr15_+_58702742 0.48 ENST00000356113.6
ENST00000414170.3
 LIPC
 lipase, hepatic
chr15_-_56209306 0.47 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr19_+_35168633 0.47 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr16_+_29471210 0.47 ENST00000360423.7
 SULT1A4
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr12_-_10007448 0.47 ENST00000538152.1
 CLEC2B
 C-type lectin domain family 2, member B
chr1_+_155290677 0.47 ENST00000368354.3
ENST00000368352.5
 RUSC1
 RUN and SH3 domain containing 1
chr14_+_45431379 0.46 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
 FAM179B
 family with sequence similarity 179, member B
chr12_+_56211703 0.46 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
 ORMDL2
 ORM1-like 2 (S. cerevisiae)
chr10_+_93558069 0.45 ENST00000371627.4
 TNKS2
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr6_+_3068606 0.45 ENST00000259808.4
 RIPK1
 receptor (TNFRSF)-interacting serine-threonine kinase 1
chr9_-_99145957 0.44 ENST00000375257.1
ENST00000253270.7
ENST00000375259.4
 SLC35D2
 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr12_-_88974236 0.44 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
 KITLG
 KIT ligand
chr8_-_6420777 0.44 ENST00000415216.1
 ANGPT2
 angiopoietin 2
chr14_-_25519095 0.43 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr19_-_45927622 0.43 ENST00000300853.3
ENST00000589165.1
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr11_-_104817919 0.43 ENST00000533252.1
 CASP4
 caspase 4, apoptosis-related cysteine peptidase
chr12_-_10151773 0.43 ENST00000298527.6
ENST00000348658.4
 CLEC1B
 C-type lectin domain family 1, member B
chr11_-_62323702 0.42 ENST00000530285.1
 AHNAK
 AHNAK nucleoprotein
chr11_-_65363259 0.42 ENST00000342202.4
 KCNK7
 potassium channel, subfamily K, member 7

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.9 18.8 GO:0051787 misfolded protein binding(GO:0051787)
0.9 8.6 GO:0045545 syndecan binding(GO:0045545)
0.7 4.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.6 6.8 GO:0042301 phosphate ion binding(GO:0042301)
0.5 2.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 12.5 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.3 GO:0070538 oleic acid binding(GO:0070538)
0.4 3.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.4 1.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 2.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 2.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 2.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 0.9 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.3 1.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3 1.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 1.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 0.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 1.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 2.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 4.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.8 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 3.1 GO:0004697 protein kinase C activity(GO:0004697)
0.1 3.8 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 1.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.3 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.8 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 1.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.8 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 1.1 GO:0017166 vinculin binding(GO:0017166)
0.1 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.6 GO:0032190 acrosin binding(GO:0032190)
0.1 7.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.4 GO:0030492 hemoglobin binding(GO:0030492)
0.1 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 5.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 3.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 5.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 1.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 6.3 GO:0005178 integrin binding(GO:0005178)
0.0 1.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.0 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 5.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 3.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 18.8 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.9 8.6 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
2.1 6.2 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
1.4 4.3 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.3 5.2 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.7 3.5 GO:1905040 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.7 5.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.6 4.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.6 1.8 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.6 2.8 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.5 1.6 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.5 2.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.5 1.5 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.5 1.4 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.5 2.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 7.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 1.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.4 2.5 GO:0090131 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.4 7.7 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.4 1.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.4 3.2 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.3 1.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 8.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.3 1.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.3 0.9 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.3 0.9 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 2.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 0.8 GO:0007412 axon target recognition(GO:0007412)
0.3 3.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.2 3.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 1.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 1.1 GO:0030070 insulin processing(GO:0030070)
0.2 0.6 GO:2000360 positive regulation of female gonad development(GO:2000196) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2 2.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.9 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 1.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 0.7 GO:0014028 notochord formation(GO:0014028)
0.2 0.6 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2 0.5 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.2 0.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 0.4 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.6 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.6 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 2.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.8 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1 0.6 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 7.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.5 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 2.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 5.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 1.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.6 GO:0006041 glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.1 3.4 GO:0015813 L-glutamate transport(GO:0015813)
0.1 0.8 GO:0001878 response to yeast(GO:0001878)
0.1 0.6 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 1.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 2.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.7 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:0090135 B-1 B cell homeostasis(GO:0001922) actin filament branching(GO:0090135)
0.1 1.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.8 GO:0007567 parturition(GO:0007567)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.6 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.9 GO:0090091 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 1.5 GO:0046697 decidualization(GO:0046697)
0.1 0.2 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.5 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 1.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.3 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.5 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.8 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0060620 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.1 0.9 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 0.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.1 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.9 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.5 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0007538 primary sex determination(GO:0007538)
0.0 1.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 1.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0071504 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0 0.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.3 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0035799 ureter maturation(GO:0035799)
0.0 0.9 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 2.4 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:2001234 negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 3.0 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.1 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 1.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.2 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 1.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.1 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.0 0.2 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.2 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.7 GO:0061053 somite development(GO:0061053)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 17.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 9.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 18.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 5.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 7.0 PID IGF1 PATHWAY IGF1 pathway
0.1 2.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 9.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 7.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0005588 collagen type V trimer(GO:0005588)
1.2 18.8 GO:0097418 neurofibrillary tangle(GO:0097418)
0.9 13.7 GO:0030478 actin cap(GO:0030478)
0.9 4.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.8 8.7 GO:0005614 interstitial matrix(GO:0005614)
0.6 2.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.6 1.8 GO:0070435 Shc-EGFR complex(GO:0070435)
0.5 3.8 GO:0036021 endolysosome lumen(GO:0036021)
0.3 3.7 GO:0097443 sorting endosome(GO:0097443)
0.3 1.6 GO:0001652 granular component(GO:0001652)
0.3 5.3 GO:0032059 bleb(GO:0032059)
0.3 3.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 3.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.6 GO:0002081 outer acrosomal membrane(GO:0002081)
0.2 2.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.9 GO:0097227 sperm annulus(GO:0097227)
0.1 1.3 GO:0071953 elastic fiber(GO:0071953)
0.1 6.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1 4.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1 1.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 3.7 GO:0031430 M band(GO:0031430)
0.1 8.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.3 GO:0031143 pseudopodium(GO:0031143)
0.1 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.4 GO:0005602 complement component C1 complex(GO:0005602)
0.1 0.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.7 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.7 GO:0043194 axon initial segment(GO:0043194)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 2.4 GO:0031941 filamentous actin(GO:0031941)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 1.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 1.2 GO:0030133 transport vesicle(GO:0030133)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 3.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 10.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.8 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 1.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.1 GO:0005901 caveola(GO:0005901)
0.0 4.3 GO:0030016 myofibril(GO:0030016)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 23.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 8.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 6.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 4.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 1.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 5.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 5.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 5.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.2 24.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 4.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 3.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 5.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 7.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 4.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.5 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions