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ENCODE cell lines, expression (Ernst 2011)

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Results for STAT4

Z-value: 0.95

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Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
STAT4
ENSG00000138378.13 STAT4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT4hg19_v2_chr2_-_192016316_1920163250.058.6e-01Click!

Activity profile of STAT4 motif

Sorted Z-values of STAT4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_190044480 3.57 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr1_-_68299130 3.52 ENST00000370982.3
 GNG12
 guanine nucleotide binding protein (G protein), gamma 12
chr10_-_95241951 3.17 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
 MYOF
 myoferlin
chr10_-_95242044 2.94 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
 MYOF
 myoferlin
chr4_+_41258786 2.42 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr15_+_63340858 2.23 ENST00000560615.1
 TPM1
 tropomyosin 1 (alpha)
chr15_+_63340734 2.16 ENST00000560959.1
 TPM1
 tropomyosin 1 (alpha)
chr15_+_63340775 2.05 ENST00000559281.1
ENST00000317516.7
 TPM1
 tropomyosin 1 (alpha)
chr15_+_63340647 2.03 ENST00000404484.4
 TPM1
 tropomyosin 1 (alpha)
chr19_+_35168567 1.99 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
 ZNF302
 zinc finger protein 302
chr10_-_126847276 1.96 ENST00000531469.1
 CTBP2
 C-terminal binding protein 2
chr19_+_35168633 1.93 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr6_+_36646435 1.92 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
 CDKN1A
 cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr5_+_140753444 1.85 ENST00000517434.1
 PCDHGA6
 protocadherin gamma subfamily A, 6
chr17_-_46682321 1.80 ENST00000225648.3
ENST00000484302.2
 HOXB6
 homeobox B6
chr7_-_41740181 1.80 ENST00000442711.1
 INHBA
 inhibin, beta A
chr19_+_35225060 1.76 ENST00000599244.1
ENST00000392232.3
 ZNF181
 zinc finger protein 181
chr3_+_159570722 1.68 ENST00000482804.1
 SCHIP1
 schwannomin interacting protein 1
chr5_-_121413974 1.52 ENST00000231004.4
 LOX
 lysyl oxidase
chr5_-_111093406 1.42 ENST00000379671.3
 NREP
 neuronal regeneration related protein
chr5_-_111092873 1.38 ENST00000509025.1
ENST00000515855.1
 NREP
 neuronal regeneration related protein
chr5_-_111093167 1.38 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr5_-_111092930 1.37 ENST00000257435.7
 NREP
 neuronal regeneration related protein
chr14_-_30396948 1.33 ENST00000331968.5
 PRKD1
 protein kinase D1
chr15_-_60690932 1.05 ENST00000559818.1
 ANXA2
 annexin A2
chr5_-_111093081 1.05 ENST00000453526.2
ENST00000509427.1
 NREP
 neuronal regeneration related protein
chr10_+_102790980 1.04 ENST00000393459.1
ENST00000224807.5
 SFXN3
 sideroflexin 3
chr3_-_114866084 1.03 ENST00000357258.3
 ZBTB20
 zinc finger and BTB domain containing 20
chr8_-_120685608 1.02 ENST00000427067.2
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr5_-_111093340 1.00 ENST00000508870.1
 NREP
 neuronal regeneration related protein
chr15_+_67458357 0.90 ENST00000537194.2
 SMAD3
 SMAD family member 3
chr6_-_32811771 0.85 ENST00000395339.3
ENST00000374882.3
 PSMB8
 proteasome (prosome, macropain) subunit, beta type, 8
chr12_+_14518598 0.83 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
 ATF7IP
 activating transcription factor 7 interacting protein
chr19_+_44669221 0.83 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
 ZNF226
 zinc finger protein 226
chr11_-_89224139 0.79 ENST00000413594.2
 NOX4
 NADPH oxidase 4
chrX_+_54834159 0.74 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
 MAGED2
 melanoma antigen family D, 2
chr14_+_24630465 0.74 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
 IRF9
 interferon regulatory factor 9
chr2_-_160473114 0.70 ENST00000392783.2
 BAZ2B
 bromodomain adjacent to zinc finger domain, 2B
chr11_-_89223883 0.69 ENST00000528341.1
 NOX4
 NADPH oxidase 4
chr19_+_10197463 0.68 ENST00000590378.1
ENST00000397881.3
 C19orf66
 chromosome 19 open reading frame 66
chr14_-_21270561 0.66 ENST00000412779.2
 RNASE1
 ribonuclease, RNase A family, 1 (pancreatic)
chr14_-_100841930 0.62 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
 WARS
 tryptophanyl-tRNA synthetase
chr12_+_58138800 0.60 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
 TSPAN31
 tetraspanin 31
chr12_+_58138664 0.59 ENST00000257910.3
 TSPAN31
 tetraspanin 31
chr8_-_27469196 0.59 ENST00000546343.1
ENST00000560566.1
 CLU
 clusterin
chr15_-_60690163 0.59 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
 ANXA2
 annexin A2
chrX_+_106045891 0.58 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
 TBC1D8B
 TBC1 domain family, member 8B (with GRAM domain)
chr11_+_123986069 0.54 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
 VWA5A
 von Willebrand factor A domain containing 5A
chr11_+_33563821 0.54 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
 KIAA1549L
 KIAA1549-like
chr14_-_100841670 0.51 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
 WARS
 tryptophanyl-tRNA synthetase
chr8_-_95274536 0.46 ENST00000297596.2
ENST00000396194.2
 GEM
 GTP binding protein overexpressed in skeletal muscle
chr6_+_134210243 0.46 ENST00000367882.4
 TCF21
 transcription factor 21
chr6_+_32821924 0.46 ENST00000374859.2
ENST00000453265.2
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr11_+_65657875 0.45 ENST00000312579.2
 CCDC85B
 coiled-coil domain containing 85B
chr8_-_27468842 0.42 ENST00000523500.1
 CLU
 clusterin
chr15_+_64680003 0.42 ENST00000261884.3
 TRIP4
 thyroid hormone receptor interactor 4
chr2_-_160472952 0.42 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
 BAZ2B
 bromodomain adjacent to zinc finger domain, 2B
chr12_+_56324756 0.36 ENST00000331886.5
ENST00000555090.1
 DGKA
 diacylglycerol kinase, alpha 80kDa
chr2_-_175547571 0.33 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
 WIPF1
 WAS/WASL interacting protein family, member 1
chr17_-_77924627 0.32 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
 TBC1D16
 TBC1 domain family, member 16
chr14_+_55034599 0.32 ENST00000392067.3
ENST00000357634.3
 SAMD4A
 sterile alpha motif domain containing 4A
chr19_-_39881777 0.32 ENST00000595564.1
ENST00000221265.3
 PAF1
 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr12_+_5541267 0.31 ENST00000423158.3
 NTF3
 neurotrophin 3
chr12_+_27396901 0.31 ENST00000541191.1
ENST00000389032.3
 STK38L
 serine/threonine kinase 38 like
chr10_-_103578182 0.31 ENST00000439817.1
 MGEA5
 meningioma expressed antigen 5 (hyaluronidase)
chrX_-_107334790 0.30 ENST00000217958.3
 PSMD10
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chrX_-_107334750 0.29 ENST00000340200.5
ENST00000372296.1
ENST00000372295.1
ENST00000361815.5
 PSMD10
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr19_-_39881669 0.28 ENST00000221266.7
 PAF1
 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr11_+_6411670 0.28 ENST00000530395.1
ENST00000527275.1
 SMPD1
 sphingomyelin phosphodiesterase 1, acid lysosomal
chr12_+_60083118 0.28 ENST00000261187.4
ENST00000543448.1
 SLC16A7
 solute carrier family 16 (monocarboxylate transporter), member 7
chr12_+_26164645 0.28 ENST00000542004.1
 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr5_+_140227048 0.27 ENST00000532602.1
 PCDHA9
 protocadherin alpha 9
chr11_-_118436707 0.26 ENST00000264020.2
ENST00000264021.3
 IFT46
 intraflagellar transport 46 homolog (Chlamydomonas)
chr1_-_9811600 0.26 ENST00000435891.1
 CLSTN1
 calsyntenin 1
chr14_+_96722539 0.26 ENST00000553356.1
 BDKRB1
 bradykinin receptor B1
chr14_+_56127989 0.25 ENST00000555573.1
 KTN1
 kinectin 1 (kinesin receptor)
chr17_-_5323480 0.25 ENST00000573584.1
 NUP88
 nucleoporin 88kDa
chr13_-_26795840 0.24 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
 RNF6
 ring finger protein (C3H2C3 type) 6
chr7_-_115670804 0.24 ENST00000320239.7
 TFEC
 transcription factor EC
chr12_+_53443963 0.24 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
 TENC1
 tensin like C1 domain containing phosphatase (tensin 2)
chr13_+_100153665 0.23 ENST00000376387.4
 TM9SF2
 transmembrane 9 superfamily member 2
chr7_-_115670792 0.23 ENST00000265440.7
ENST00000393485.1
 TFEC
 transcription factor EC
chr5_+_179921344 0.22 ENST00000261951.4
 CNOT6
 CCR4-NOT transcription complex, subunit 6
chr1_+_17906970 0.22 ENST00000375415.1
 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
chr2_+_210444748 0.21 ENST00000392194.1
 MAP2
 microtubule-associated protein 2
chr12_+_56435637 0.20 ENST00000356464.5
ENST00000552361.1
 RPS26
 ribosomal protein S26
chrX_+_138612889 0.19 ENST00000218099.2
ENST00000394090.2
 F9
 coagulation factor IX
chr13_-_41240717 0.19 ENST00000379561.5
 FOXO1
 forkhead box O1
chr3_-_126327398 0.18 ENST00000383572.2
 TXNRD3NB
 thioredoxin reductase 3 neighbor
chr17_-_58603568 0.17 ENST00000083182.3
 APPBP2
 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chrX_-_65253506 0.15 ENST00000427538.1
 VSIG4
 V-set and immunoglobulin domain containing 4
chr10_-_116444371 0.14 ENST00000533213.2
ENST00000369252.4
 ABLIM1
 actin binding LIM protein 1
chr6_+_25754927 0.14 ENST00000377905.4
ENST00000439485.2
 SLC17A4
 solute carrier family 17, member 4
chr7_-_82792215 0.13 ENST00000333891.9
ENST00000423517.2
 PCLO
 piccolo presynaptic cytomatrix protein
chr6_-_49712123 0.11 ENST00000263045.4
 CRISP3
 cysteine-rich secretory protein 3
chr1_-_211752073 0.11 ENST00000367001.4
 SLC30A1
 solute carrier family 30 (zinc transporter), member 1
chr11_-_64490634 0.10 ENST00000377559.3
ENST00000265459.6
 NRXN2
 neurexin 2
chr22_-_50699701 0.09 ENST00000395780.1
 MAPK12
 mitogen-activated protein kinase 12
chr16_+_4674787 0.08 ENST00000262370.7
 MGRN1
 mahogunin ring finger 1, E3 ubiquitin protein ligase
chr3_-_57678772 0.08 ENST00000311128.5
 DENND6A
 DENN/MADD domain containing 6A
chr3_-_194119995 0.08 ENST00000323007.3
 GP5
 glycoprotein V (platelet)
chr15_-_75660919 0.06 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
 MAN2C1
 mannosidase, alpha, class 2C, member 1
chr22_-_31536480 0.06 ENST00000215885.3
 PLA2G3
 phospholipase A2, group III
chr5_-_64777733 0.06 ENST00000381055.3
 ADAMTS6
 ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr11_+_128563652 0.05 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr1_-_143767881 0.05 ENST00000419275.1
 PPIAL4G
 peptidylprolyl isomerase A (cyclophilin A)-like 4G
chr7_-_42971759 0.05 ENST00000538645.1
ENST00000445517.1
ENST00000223321.4
 PSMA2
 proteasome (prosome, macropain) subunit, alpha type, 2
chr3_+_122296465 0.05 ENST00000483793.1
 PARP15
 poly (ADP-ribose) polymerase family, member 15
chr12_+_20848282 0.04 ENST00000545604.1
 SLCO1C1
 solute carrier organic anion transporter family, member 1C1
chr11_+_118175132 0.04 ENST00000361763.4
 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
chr1_+_9299895 0.03 ENST00000602477.1
 H6PD
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr5_-_140013275 0.03 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
 CD14
 CD14 molecule
chr1_-_144364246 0.02 ENST00000540273.1
 PPIAL4B
 peptidylprolyl isomerase A (cyclophilin A)-like 4B
chr15_+_57998923 0.01 ENST00000380557.4
 POLR2M
 polymerase (RNA) II (DNA directed) polypeptide M
chr3_-_164875850 0.01 ENST00000472120.1
 RP11-747D18.1
 RP11-747D18.1
chr9_-_116163400 0.01 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
 ALAD
 aminolevulinate dehydratase
chr17_+_7358889 0.01 ENST00000575379.1
 CHRNB1
 cholinergic receptor, nicotinic, beta 1 (muscle)
chr2_+_231921574 0.01 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
 PSMD1
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr9_-_95166884 0.01 ENST00000375561.5
 OGN
 osteoglycin
chr1_-_161519682 0.01 ENST00000367969.3
ENST00000443193.1
 FCGR3A
 Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr12_+_56324933 0.01 ENST00000549629.1
ENST00000555218.1
 DGKA
 diacylglycerol kinase, alpha 80kDa
chr16_+_58283814 0.00 ENST00000443128.2
ENST00000219299.4
 CCDC113
 coiled-coil domain containing 113
chr6_-_32821599 0.00 ENST00000354258.4
 TAP1
 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6 2.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.6 1.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 3.5 GO:0042301 phosphate ion binding(GO:0042301)
0.3 2.0 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3 1.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 1.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 8.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 3.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 5.9 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.9 3.6 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.8 2.4 GO:0007412 axon target recognition(GO:0007412)
0.6 1.8 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5 1.6 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.5 6.1 GO:0001778 plasma membrane repair(GO:0001778)
0.4 1.9 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 1.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 2.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 1.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 0.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 1.0 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.5 GO:0072275 branchiomeric skeletal muscle development(GO:0014707) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 1.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 3.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0 1.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.3 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.8 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 8.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 4.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0005588 collagen type V trimer(GO:0005588)
0.6 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 1.8 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 8.5 GO:0032059 bleb(GO:0032059)
0.3 1.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 2.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 3.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 2.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 5.8 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)