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ENCODE cell lines, expression (Ernst 2011)

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Results for STAT5A

Z-value: 1.22

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
STAT5A
ENSG00000126561.12 STAT5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_40440561-0.126.6e-01Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_159046617 3.32 ENST00000368130.4
 AIM2
 absent in melanoma 2
chr6_+_32605195 2.37 ENST00000374949.2
 HLA-DQA1
 major histocompatibility complex, class II, DQ alpha 1
chr22_+_23241661 2.36 ENST00000390322.2
 IGLJ2
 immunoglobulin lambda joining 2
chr21_+_42792442 2.16 ENST00000398600.2
 MX1
 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr14_+_75988851 2.15 ENST00000555504.1
 BATF
 basic leucine zipper transcription factor, ATF-like
chr3_+_50649302 2.08 ENST00000446044.1
 MAPKAPK3
 mitogen-activated protein kinase-activated protein kinase 3
chr6_+_32407619 2.05 ENST00000395388.2
ENST00000374982.5
 HLA-DRA
 major histocompatibility complex, class II, DR alpha
chr4_-_71532339 1.87 ENST00000254801.4
 IGJ
 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr13_-_99959641 1.83 ENST00000376414.4
 GPR183
 G protein-coupled receptor 183
chr13_-_46964177 1.75 ENST00000389908.3
 KIAA0226L
 KIAA0226-like
chr22_+_23247030 1.73 ENST00000390324.2
 IGLJ3
 immunoglobulin lambda joining 3
chr1_+_158975744 1.61 ENST00000426592.2
 IFI16
 interferon, gamma-inducible protein 16
chr2_-_38303218 1.56 ENST00000407341.1
ENST00000260630.3
 CYP1B1
 cytochrome P450, family 1, subfamily B, polypeptide 1
chr11_+_121461097 1.55 ENST00000527934.1
 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
chr15_-_38856836 1.54 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr7_-_37026108 1.51 ENST00000396045.3
 ELMO1
 engulfment and cell motility 1
chr6_+_32605134 1.51 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
 HLA-DQA1
 major histocompatibility complex, class II, DQ alpha 1
chr18_-_67624160 1.50 ENST00000581982.1
ENST00000280200.4
 CD226
 CD226 molecule
chr5_-_138725594 1.38 ENST00000302125.8
 MZB1
 marginal zone B and B1 cell-specific protein
chr5_-_138725560 1.38 ENST00000412103.2
ENST00000457570.2
 MZB1
 marginal zone B and B1 cell-specific protein
chr1_+_111415757 1.36 ENST00000429072.2
ENST00000271324.5
 CD53
 CD53 molecule
chr20_-_43280361 1.31 ENST00000372874.4
 ADA
 adenosine deaminase
chr6_+_33048222 1.31 ENST00000428835.1
 HLA-DPB1
 major histocompatibility complex, class II, DP beta 1
chr14_+_21249200 1.29 ENST00000304677.2
 RNASE6
 ribonuclease, RNase A family, k6
chr2_+_163200848 1.25 ENST00000233612.4
 GCA
 grancalcin, EF-hand calcium binding protein
chr1_+_158801095 1.24 ENST00000368141.4
 MNDA
 myeloid cell nuclear differentiation antigen
chr6_-_32820529 1.24 ENST00000425148.2
 TAP1
 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_32634425 1.18 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
 HLA-DQB1
 major histocompatibility complex, class II, DQ beta 1
chr4_-_40517984 1.15 ENST00000381795.6
 RBM47
 RNA binding motif protein 47
chr16_+_27413483 1.15 ENST00000337929.3
ENST00000564089.1
 IL21R
 interleukin 21 receptor
chr6_+_116692102 1.14 ENST00000359564.2
 DSE
 dermatan sulfate epimerase
chr19_+_18284477 1.14 ENST00000407280.3
 IFI30
 interferon, gamma-inducible protein 30
chr6_-_137539651 1.13 ENST00000543628.1
 IFNGR1
 interferon gamma receptor 1
chr11_+_7618413 1.07 ENST00000528883.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_+_74188309 1.04 ENST00000289473.4
ENST00000433458.1
 NCF1
 neutrophil cytosolic factor 1
chr2_-_89292422 1.03 ENST00000495489.1
 IGKV1-8
 immunoglobulin kappa variable 1-8
chr2_-_175547571 1.03 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
 WIPF1
 WAS/WASL interacting protein family, member 1
chr10_+_90750378 1.02 ENST00000355740.2
ENST00000352159.4
 FAS
 Fas cell surface death receptor
chr17_-_29641104 1.01 ENST00000577894.1
ENST00000330927.4
 EVI2B
 ecotropic viral integration site 2B
chr4_-_40631859 1.01 ENST00000295971.7
ENST00000319592.4
 RBM47
 RNA binding motif protein 47
chr7_+_7606497 0.96 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
 MIOS
 missing oocyte, meiosis regulator, homolog (Drosophila)
chr6_+_31540056 0.95 ENST00000418386.2
 LTA
 lymphotoxin alpha
chr17_+_41158742 0.94 ENST00000415816.2
ENST00000438323.2
 IFI35
 interferon-induced protein 35
chr17_-_29641084 0.88 ENST00000544462.1
 EVI2B
 ecotropic viral integration site 2B
chr2_-_191878162 0.88 ENST00000540176.1
 STAT1
 signal transducer and activator of transcription 1, 91kDa
chr20_-_43280325 0.86 ENST00000537820.1
 ADA
 adenosine deaminase
chr17_-_34207295 0.85 ENST00000463941.1
ENST00000293272.3
 CCL5
 chemokine (C-C motif) ligand 5
chr1_+_158979792 0.85 ENST00000359709.3
ENST00000430894.2
 IFI16
 interferon, gamma-inducible protein 16
chr4_+_15779901 0.84 ENST00000226279.3
 CD38
 CD38 molecule
chr22_+_37257015 0.81 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
 NCF4
 neutrophil cytosolic factor 4, 40kDa
chr4_-_38806404 0.80 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
 TLR1
 toll-like receptor 1
chr10_+_90750493 0.79 ENST00000357339.2
ENST00000355279.2
 FAS
 Fas cell surface death receptor
chr14_-_106963409 0.78 ENST00000390621.2
 IGHV1-45
 immunoglobulin heavy variable 1-45
chr12_-_15103621 0.78 ENST00000536592.1
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr1_+_158979680 0.78 ENST00000368131.4
ENST00000340979.6
 IFI16
 interferon, gamma-inducible protein 16
chr1_+_158979686 0.77 ENST00000368132.3
ENST00000295809.7
 IFI16
 interferon, gamma-inducible protein 16
chrX_+_107288197 0.76 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr16_-_11681316 0.76 ENST00000571688.1
 LITAF
 lipopolysaccharide-induced TNF factor
chr19_+_10197463 0.75 ENST00000590378.1
ENST00000397881.3
 C19orf66
 chromosome 19 open reading frame 66
chr12_+_21207503 0.75 ENST00000545916.1
 SLCO1B7
 solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_+_7541808 0.74 ENST00000379802.3
 DSP
 desmoplakin
chr1_+_158969752 0.74 ENST00000566111.1
 IFI16
 interferon, gamma-inducible protein 16
chrX_+_107288239 0.73 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr22_-_24096562 0.73 ENST00000398465.3
 VPREB3
 pre-B lymphocyte 3
chr1_+_213123976 0.73 ENST00000366965.2
ENST00000366967.2
 VASH2
 vasohibin 2
chr1_+_35247859 0.72 ENST00000373362.3
 GJB3
 gap junction protein, beta 3, 31kDa
chr3_-_79816965 0.72 ENST00000464233.1
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_-_41703952 0.72 ENST00000358871.2
ENST00000403298.4
 TFEB
 transcription factor EB
chr2_+_90198535 0.71 ENST00000390276.2
 IGKV1D-12
 immunoglobulin kappa variable 1D-12
chr22_-_45636650 0.71 ENST00000336156.5
 KIAA0930
 KIAA0930
chr11_-_615570 0.71 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
 IRF7
 interferon regulatory factor 7
chr19_-_6604094 0.70 ENST00000597430.2
 CD70
 CD70 molecule
chr22_-_37640456 0.68 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_+_112051994 0.67 ENST00000473539.1
ENST00000315711.8
ENST00000383681.3
 CD200
 CD200 molecule
chr14_+_64680854 0.66 ENST00000458046.2
 SYNE2
 spectrin repeat containing, nuclear envelope 2
chr16_-_67517716 0.66 ENST00000290953.2
 AGRP
 agouti related protein homolog (mouse)
chr6_-_22297730 0.66 ENST00000306482.1
 PRL
 prolactin
chr11_-_87908600 0.65 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
 RAB38
 RAB38, member RAS oncogene family
chr4_+_47487285 0.65 ENST00000273859.3
ENST00000504445.1
 ATP10D
 ATPase, class V, type 10D
chr1_+_213123915 0.64 ENST00000366968.4
ENST00000490792.1
 VASH2
 vasohibin 2
chr17_+_12692774 0.64 ENST00000379672.5
ENST00000340825.3
 ARHGAP44
 Rho GTPase activating protein 44
chr4_+_142558078 0.64 ENST00000529613.1
 IL15
 interleukin 15
chr2_-_89399845 0.64 ENST00000479981.1
 IGKV1-16
 immunoglobulin kappa variable 1-16
chr2_+_102972363 0.63 ENST00000409599.1
 IL18R1
 interleukin 18 receptor 1
chr16_+_50730910 0.63 ENST00000300589.2
 NOD2
 nucleotide-binding oligomerization domain containing 2
chr9_-_88356733 0.62 ENST00000376083.3
 AGTPBP1
 ATP/GTP binding protein 1
chr7_+_55980331 0.62 ENST00000429591.2
 ZNF713
 zinc finger protein 713
chr12_+_113416191 0.62 ENST00000342315.4
ENST00000392583.2
 OAS2
 2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr14_-_25519095 0.60 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr4_+_75858290 0.60 ENST00000513238.1
 PARM1
 prostate androgen-regulated mucin-like protein 1
chr4_+_142557771 0.60 ENST00000514653.1
 IL15
 interleukin 15
chr20_+_34203794 0.60 ENST00000374273.3
 SPAG4
 sperm associated antigen 4
chr14_-_25479811 0.60 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr10_-_116444371 0.60 ENST00000533213.2
ENST00000369252.4
 ABLIM1
 actin binding LIM protein 1
chr21_+_34602680 0.59 ENST00000447980.1
 IFNAR2
 interferon (alpha, beta and omega) receptor 2
chr19_+_36203830 0.59 ENST00000262630.3
 ZBTB32
 zinc finger and BTB domain containing 32
chr19_-_10446449 0.58 ENST00000592439.1
 ICAM3
 intercellular adhesion molecule 3
chr12_+_58138664 0.58 ENST00000257910.3
 TSPAN31
 tetraspanin 31
chr17_-_9929581 0.57 ENST00000437099.2
ENST00000396115.2
 GAS7
 growth arrest-specific 7
chr19_+_10381769 0.57 ENST00000423829.2
ENST00000588645.1
 ICAM1
 intercellular adhesion molecule 1
chr10_+_26727125 0.56 ENST00000376236.4
 APBB1IP
 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr12_+_103351444 0.56 ENST00000266744.3
 ASCL1
 achaete-scute family bHLH transcription factor 1
chr8_-_120651020 0.55 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr9_+_112542591 0.54 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
 PALM2
PALM2-AKAP2
AKAP2
 paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr9_-_88356789 0.54 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
 AGTPBP1
 ATP/GTP binding protein 1
chr6_+_20534672 0.54 ENST00000274695.4
ENST00000378624.4
 CDKAL1
 CDK5 regulatory subunit associated protein 1-like 1
chr20_-_18774614 0.53 ENST00000412553.1
 LINC00652
 long intergenic non-protein coding RNA 652
chr8_-_61880248 0.53 ENST00000525556.1
 AC022182.3
 AC022182.3
chr13_+_111767650 0.53 ENST00000449979.1
ENST00000370623.3
 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
chr21_+_34602377 0.53 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
 IFNAR2
 interferon (alpha, beta and omega) receptor 2
chr6_+_31582961 0.53 ENST00000376059.3
ENST00000337917.7
 AIF1
 allograft inflammatory factor 1
chrX_+_1455478 0.53 ENST00000331035.4
 IL3RA
 interleukin 3 receptor, alpha (low affinity)
chr14_+_61789382 0.53 ENST00000555082.1
 PRKCH
 protein kinase C, eta
chr22_-_24096630 0.52 ENST00000248948.3
 VPREB3
 pre-B lymphocyte 3
chr17_-_39928106 0.52 ENST00000540235.1
 JUP
 junction plakoglobin
chr8_-_102803163 0.52 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
 NCALD
 neurocalcin delta
chr12_+_133657461 0.52 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
 ZNF140
 zinc finger protein 140
chr19_-_51875894 0.52 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
 NKG7
 natural killer cell group 7 sequence
chr14_-_20801427 0.51 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
 CCNB1IP1
 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr12_+_58138800 0.51 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
 TSPAN31
 tetraspanin 31
chr19_+_44507091 0.51 ENST00000429154.2
ENST00000585632.1
 ZNF230
 zinc finger protein 230
chr10_+_30722866 0.50 ENST00000263056.1
 MAP3K8
 mitogen-activated protein kinase kinase kinase 8
chr21_+_34602200 0.49 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
 IFNAR2
 interferon (alpha, beta and omega) receptor 2
chr1_+_12123414 0.49 ENST00000263932.2
 TNFRSF8
 tumor necrosis factor receptor superfamily, member 8
chr15_+_91643442 0.49 ENST00000394232.1
 SV2B
 synaptic vesicle glycoprotein 2B
chr11_+_5617952 0.49 ENST00000354852.5
 TRIM6-TRIM34
 TRIM6-TRIM34 readthrough
chr2_+_65216462 0.48 ENST00000234256.3
 SLC1A4
 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr22_-_37640277 0.48 ENST00000401529.3
ENST00000249071.6
 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_-_152955213 0.47 ENST00000427385.1
 CACNB4
 calcium channel, voltage-dependent, beta 4 subunit
chr13_-_41706864 0.47 ENST00000379485.1
ENST00000499385.2
 KBTBD6
 kelch repeat and BTB (POZ) domain containing 6
chr18_+_61442629 0.47 ENST00000398019.2
ENST00000540675.1
 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_-_68647281 0.47 ENST00000328087.4
ENST00000538666.1
 IL22
 interleukin 22
chr12_-_15114492 0.46 ENST00000541546.1
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr1_-_17216143 0.46 ENST00000457075.1
 RP11-108M9.4
 RP11-108M9.4
chr12_+_56324756 0.46 ENST00000331886.5
ENST00000555090.1
 DGKA
 diacylglycerol kinase, alpha 80kDa
chr14_+_88471468 0.46 ENST00000267549.3
 GPR65
 G protein-coupled receptor 65
chr18_+_20513782 0.45 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
 RBBP8
 retinoblastoma binding protein 8
chr6_-_32731299 0.45 ENST00000435145.2
ENST00000437316.2
 HLA-DQB2
 major histocompatibility complex, class II, DQ beta 2
chrX_-_30595959 0.45 ENST00000378962.3
 CXorf21
 chromosome X open reading frame 21
chrX_-_148571884 0.44 ENST00000537071.1
 IDS
 iduronate 2-sulfatase
chr19_+_55128576 0.44 ENST00000396331.1
 LILRB1
 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr10_-_103815874 0.44 ENST00000370033.4
ENST00000311122.5
 C10orf76
 chromosome 10 open reading frame 76
chr2_-_152955537 0.44 ENST00000201943.5
ENST00000539935.1
 CACNB4
 calcium channel, voltage-dependent, beta 4 subunit
chr5_-_169725231 0.44 ENST00000046794.5
 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr2_+_85804614 0.44 ENST00000263864.5
ENST00000409760.1
 VAMP8
 vesicle-associated membrane protein 8
chr12_-_8815299 0.43 ENST00000535336.1
 MFAP5
 microfibrillar associated protein 5
chr19_-_51522955 0.43 ENST00000358789.3
 KLK10
 kallikrein-related peptidase 10
chr15_+_75335604 0.43 ENST00000563393.1
 PPCDC
 phosphopantothenoylcysteine decarboxylase
chr12_+_10658201 0.43 ENST00000322446.3
 EIF2S3L
 Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr17_-_76356148 0.42 ENST00000587578.1
ENST00000330871.2
 SOCS3
 suppressor of cytokine signaling 3
chr11_-_104827425 0.42 ENST00000393150.3
 CASP4
 caspase 4, apoptosis-related cysteine peptidase
chr17_+_2699697 0.42 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
 RAP1GAP2
 RAP1 GTPase activating protein 2
chr12_-_117537240 0.42 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
 TESC
 tescalcin
chr3_+_141144954 0.42 ENST00000441582.2
ENST00000321464.5
 ZBTB38
 zinc finger and BTB domain containing 38
chr19_+_44081344 0.42 ENST00000599207.1
 PINLYP
 phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr12_-_15114603 0.42 ENST00000228945.4
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr2_+_90139056 0.41 ENST00000492446.1
 IGKV1D-16
 immunoglobulin kappa variable 1D-16
chr1_-_17215868 0.41 ENST00000422124.1
 RP11-108M9.4
 RP11-108M9.4
chr19_+_35168567 0.41 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
 ZNF302
 zinc finger protein 302
chr1_-_230850043 0.41 ENST00000366667.4
 AGT
 angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr20_-_18447667 0.41 ENST00000262547.5
ENST00000329494.5
ENST00000357236.4
 DZANK1
 double zinc ribbon and ankyrin repeat domains 1
chr12_-_8815215 0.41 ENST00000544889.1
ENST00000543369.1
 MFAP5
 microfibrillar associated protein 5
chr18_-_7117813 0.41 ENST00000389658.3
 LAMA1
 laminin, alpha 1
chr1_+_46640750 0.41 ENST00000372003.1
 TSPAN1
 tetraspanin 1
chr16_-_58585513 0.41 ENST00000245138.4
ENST00000567285.1
 CNOT1
 CCR4-NOT transcription complex, subunit 1
chr14_-_106866934 0.40 ENST00000390618.2
 IGHV3-38
 immunoglobulin heavy variable 3-38 (non-functional)
chr6_-_26189304 0.40 ENST00000340756.2
 HIST1H4D
 histone cluster 1, H4d
chr2_-_264024 0.40 ENST00000403712.2
ENST00000356150.5
ENST00000405430.1
 SH3YL1
 SH3 and SYLF domain containing 1
chr3_-_4793274 0.40 ENST00000414938.1
 EGOT
 eosinophil granule ontogeny transcript (non-protein coding)
chr2_-_113594279 0.40 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B
 interleukin 1, beta
chr2_+_74056066 0.40 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
 STAMBP
 STAM binding protein
chr11_+_58912240 0.40 ENST00000527629.1
ENST00000361723.3
ENST00000531408.1
 FAM111A
 family with sequence similarity 111, member A
chr3_+_178525080 0.39 ENST00000358316.3
 KCNMB2
 potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr2_-_89340242 0.39 ENST00000480492.1
 IGKV1-12
 immunoglobulin kappa variable 1-12
chr11_+_85955787 0.38 ENST00000528180.1
 EED
 embryonic ectoderm development
chr11_-_104905840 0.38 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
 CASP1
 caspase 1, apoptosis-related cysteine peptidase
chr12_-_52967600 0.38 ENST00000549343.1
ENST00000305620.2
 KRT74
 keratin 74
chr12_+_56324933 0.38 ENST00000549629.1
ENST00000555218.1
 DGKA
 diacylglycerol kinase, alpha 80kDa
chr1_-_17216109 0.38 ENST00000416869.1
 RP11-108M9.4
 RP11-108M9.4
chr9_-_15510989 0.38 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
 PSIP1
 PC4 and SFRS1 interacting protein 1
chr1_-_45140074 0.38 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
 TMEM53
 transmembrane protein 53
chr1_+_181003067 0.37 ENST00000434571.2
ENST00000367579.3
ENST00000282990.6
ENST00000367580.5
 MR1
 major histocompatibility complex, class I-related
chr1_+_26503894 0.37 ENST00000361530.6
ENST00000374253.5
 CNKSR1
 connector enhancer of kinase suppressor of Ras 1
chr12_-_8814669 0.37 ENST00000535411.1
ENST00000540087.1
 MFAP5
 microfibrillar associated protein 5
chr5_-_169694286 0.37 ENST00000521416.1
ENST00000520344.1
 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_+_35168633 0.37 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr19_+_42724423 0.37 ENST00000301215.3
ENST00000597945.1
 ZNF526
 zinc finger protein 526
chr11_+_9685604 0.36 ENST00000447399.2
ENST00000318950.6
 SWAP70
 SWAP switching B-cell complex 70kDa subunit
chr22_+_25003626 0.36 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
 GGT1
 gamma-glutamyltransferase 1
chr12_+_20968608 0.36 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
 LST3
SLCO1B3
SLCO1B7
 Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr4_-_38858428 0.36 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
 TLR6
TLR1
 toll-like receptor 6
toll-like receptor 1
chr14_-_107078851 0.35 ENST00000390628.2
 IGHV1-58
 immunoglobulin heavy variable 1-58
chr19_+_16186903 0.35 ENST00000588507.1
 TPM4
 tropomyosin 4
chr7_+_117120017 0.35 ENST00000003084.6
ENST00000454343.1
 CFTR
 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr20_+_35973080 0.35 ENST00000445403.1
 SRC
 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr17_+_76356516 0.35 ENST00000592569.1
 RP11-806H10.4
 RP11-806H10.4
chr3_-_148939835 0.35 ENST00000264613.6
 CP
 ceruloplasmin (ferroxidase)
chr8_+_27168988 0.35 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
 PTK2B
 protein tyrosine kinase 2 beta
chr5_+_32585605 0.35 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
 SUB1
 SUB1 homolog (S. cerevisiae)
chr4_-_185395672 0.34 ENST00000393593.3
 IRF2
 interferon regulatory factor 2

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.9 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.4 9.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 1.2 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 1.9 GO:0032010 phagolysosome(GO:0032010)
0.2 1.1 GO:0036398 TCR signalosome(GO:0036398)
0.2 1.2 GO:0042825 TAP complex(GO:0042825)
0.2 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 2.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.7 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.1 1.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.5 GO:0000322 storage vacuole(GO:0000322)
0.1 1.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 3.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0046102 hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102)
0.6 1.8 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.6 1.8 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.6 2.8 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.5 1.5 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.5 2.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5 3.5 GO:0070269 pyroptosis(GO:0070269)
0.4 2.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.4 2.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.4 1.7 GO:0071461 cellular response to redox state(GO:0071461)
0.4 1.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.4 2.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.4 1.2 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4 1.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 0.9 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.3 1.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 1.8 GO:0036337 Fas signaling pathway(GO:0036337)
0.3 2.1 GO:0044351 macropinocytosis(GO:0044351)
0.3 1.5 GO:0032252 secretory granule localization(GO:0032252)
0.2 2.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 0.7 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 0.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.9 GO:0072183 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.2 0.4 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) negative regulation of response to DNA damage stimulus(GO:2001021)
0.2 0.7 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.5 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.5 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 0.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.4 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 1.5 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.4 GO:0061461 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 1.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.4 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.7 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.3 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.3 GO:1990641 cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1 0.5 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 1.8 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.1 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
0.1 0.7 GO:1903232 melanosome assembly(GO:1903232)
0.1 4.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.6 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.5 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.3 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 1.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 9.6 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.7 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.1 0.5 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.6 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.6 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.9 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.2 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 1.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.4 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.1 1.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.5 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.3 GO:0072141 renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1 0.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 1.0 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 0.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.0 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.0 1.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.4 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:1902994 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0097254 renal tubular secretion(GO:0097254)
0.0 0.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.8 GO:0045730 respiratory burst(GO:0045730)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.3 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.3 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.0 0.0 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252) regulation of forebrain neuron differentiation(GO:2000977)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.6 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 1.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.7 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.5 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:1904597 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0 2.8 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.0 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.0 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 1.1 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.7 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0060068 vagina development(GO:0060068)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.0 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.8 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.5 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.8 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:1901538 DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.6 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.0 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.5 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.6 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.0 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.5 GO:0046427 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.0 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 1.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 1.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.4 1.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 1.8 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 1.6 GO:0004905 type I interferon receptor activity(GO:0004905)
0.3 0.8 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.3 2.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 1.8 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 0.7 GO:0005148 prolactin receptor binding(GO:0005148)
0.2 1.2 GO:0046979 TAP2 binding(GO:0046979)
0.2 0.6 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 0.5 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 1.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.7 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.5 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.4 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.8 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.1 0.5 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 2.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 1.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.1 1.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.2 GO:0051765 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 2.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.2 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 1.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.6 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.3 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 5.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 1.2 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 1.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 3.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0001047 core promoter binding(GO:0001047)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 3.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 6.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 2.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling