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ENCODE cell lines, expression (Ernst 2011)

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Results for STAT5B

Z-value: 0.88

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Transcription factors associated with STAT5B

Gene Symbol Gene ID Gene Info
STAT5B
ENSG00000173757.5 STAT5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Bhg19_v2_chr17_-_40428359_40428462-0.214.3e-01Click!

Activity profile of STAT5B motif

Sorted Z-values of STAT5B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5B

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrY_+_2709527 2.18 ENST00000250784.8
 RPS4Y1
 ribosomal protein S4, Y-linked 1
chrY_+_2709906 2.13 ENST00000430575.1
 RPS4Y1
 ribosomal protein S4, Y-linked 1
chr5_-_111092930 1.88 ENST00000257435.7
 NREP
 neuronal regeneration related protein
chr19_+_35168567 1.53 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
 ZNF302
 zinc finger protein 302
chr5_-_111093167 1.50 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr19_+_35168633 1.42 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr19_+_54024251 1.38 ENST00000253144.9
 ZNF331
 zinc finger protein 331
chr9_+_112542591 1.34 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
 PALM2
PALM2-AKAP2
AKAP2
 paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr5_-_111092873 1.31 ENST00000509025.1
ENST00000515855.1
 NREP
 neuronal regeneration related protein
chr5_-_111093081 1.24 ENST00000453526.2
ENST00000509427.1
 NREP
 neuronal regeneration related protein
chr5_-_95158644 1.17 ENST00000237858.6
 GLRX
 glutaredoxin (thioltransferase)
chr5_-_111093340 1.06 ENST00000508870.1
 NREP
 neuronal regeneration related protein
chr19_+_44669221 1.00 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
 ZNF226
 zinc finger protein 226
chr12_+_102271129 0.94 ENST00000258534.8
 DRAM1
 DNA-damage regulated autophagy modulator 1
chr5_-_95158375 0.84 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX
 glutaredoxin (thioltransferase)
chr19_-_44860820 0.83 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
 ZNF112
 zinc finger protein 112
chr19_+_44556158 0.78 ENST00000434772.3
ENST00000585552.1
 ZNF223
 zinc finger protein 223
chr18_-_53253323 0.76 ENST00000540999.1
ENST00000563888.2
 TCF4
 transcription factor 4
chr19_+_54041333 0.75 ENST00000411977.2
ENST00000511154.1
 ZNF331
 zinc finger protein 331
chr17_+_32582293 0.74 ENST00000580907.1
ENST00000225831.4
 CCL2
 chemokine (C-C motif) ligand 2
chr12_+_133657461 0.72 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
 ZNF140
 zinc finger protein 140
chr17_+_48624450 0.72 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
 SPATA20
 spermatogenesis associated 20
chr5_-_42812143 0.70 ENST00000514985.1
 SEPP1
 selenoprotein P, plasma, 1
chr1_+_149871135 0.66 ENST00000369152.5
 BOLA1
 bolA family member 1
chr19_+_56652556 0.60 ENST00000337080.3
 ZNF444
 zinc finger protein 444
chr19_+_56652686 0.55 ENST00000592949.1
 ZNF444
 zinc finger protein 444
chr19_-_46366392 0.53 ENST00000598059.1
ENST00000594293.1
ENST00000245934.7
 SYMPK
 symplekin
chr4_-_155511887 0.52 ENST00000302053.3
ENST00000403106.3
 FGA
 fibrinogen alpha chain
chr14_-_70883708 0.52 ENST00000256366.4
 SYNJ2BP
 synaptojanin 2 binding protein
chrX_-_154250989 0.51 ENST00000360256.4
 F8
 coagulation factor VIII, procoagulant component
chr1_+_220921582 0.51 ENST00000359316.2
 MARC2
 mitochondrial amidoxime reducing component 2
chr19_+_44507091 0.51 ENST00000429154.2
ENST00000585632.1
 ZNF230
 zinc finger protein 230
chr11_-_82997013 0.46 ENST00000529073.1
ENST00000529611.1
 CCDC90B
 coiled-coil domain containing 90B
chrX_+_106045891 0.46 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
 TBC1D8B
 TBC1 domain family, member 8B (with GRAM domain)
chr5_+_178450753 0.46 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
 ZNF879
 zinc finger protein 879
chr9_+_104161123 0.41 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
 ZNF189
 zinc finger protein 189
chr19_+_42746927 0.40 ENST00000378108.1
 AC006486.1
 AC006486.1
chr1_+_220921640 0.40 ENST00000366913.3
 MARC2
 mitochondrial amidoxime reducing component 2
chr4_-_89080003 0.39 ENST00000237612.3
 ABCG2
 ATP-binding cassette, sub-family G (WHITE), member 2
chr16_-_89785777 0.39 ENST00000561976.1
 VPS9D1
 VPS9 domain containing 1
chr19_+_44598534 0.39 ENST00000336976.6
 ZNF224
 zinc finger protein 224
chr19_+_58038683 0.38 ENST00000240719.3
ENST00000376233.3
ENST00000594943.1
ENST00000602149.1
 ZNF549
 zinc finger protein 549
chr17_-_80291818 0.38 ENST00000269389.3
ENST00000581691.1
 SECTM1
 secreted and transmembrane 1
chr17_-_26697304 0.38 ENST00000536498.1
 VTN
 vitronectin
chr11_-_82997420 0.38 ENST00000455220.2
ENST00000529689.1
 CCDC90B
 coiled-coil domain containing 90B
chr14_-_82000140 0.37 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
 SEL1L
 sel-1 suppressor of lin-12-like (C. elegans)
chr6_+_139094657 0.37 ENST00000332797.6
 CCDC28A
 coiled-coil domain containing 28A
chr17_-_34308524 0.36 ENST00000293275.3
 CCL16
 chemokine (C-C motif) ligand 16
chr16_-_18462221 0.35 ENST00000528301.1
 RP11-1212A22.4
 LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr4_+_155484155 0.35 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr3_+_14166440 0.35 ENST00000306077.4
 TMEM43
 transmembrane protein 43
chr14_+_23235886 0.33 ENST00000604262.1
ENST00000431881.2
ENST00000412791.1
ENST00000358043.5
 OXA1L
 oxidase (cytochrome c) assembly 1-like
chr19_+_35225060 0.33 ENST00000599244.1
ENST00000392232.3
 ZNF181
 zinc finger protein 181
chr20_-_43280325 0.33 ENST00000537820.1
 ADA
 adenosine deaminase
chr19_-_57988871 0.32 ENST00000596831.1
ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
 AC004076.9
ZNF772
 Uncharacterized protein
zinc finger protein 772
chr8_+_17780483 0.31 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
 PCM1
 pericentriolar material 1
chrX_+_107288239 0.31 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr15_+_67420441 0.30 ENST00000558894.1
 SMAD3
 SMAD family member 3
chr7_-_93633684 0.30 ENST00000222547.3
ENST00000425626.1
 BET1
 Bet1 golgi vesicular membrane trafficking protein
chr11_-_82997371 0.30 ENST00000525503.1
 CCDC90B
 coiled-coil domain containing 90B
chr1_+_54519242 0.30 ENST00000234827.1
 TCEANC2
 transcription elongation factor A (SII) N-terminal and central domain containing 2
chr10_+_93558069 0.30 ENST00000371627.4
 TNKS2
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chrX_+_107288197 0.30 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr20_+_35973080 0.29 ENST00000445403.1
 SRC
 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr2_+_70121075 0.29 ENST00000409116.1
 SNRNP27
 small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr9_+_130186653 0.28 ENST00000342483.5
ENST00000543471.1
 ZNF79
 zinc finger protein 79
chr7_-_93633658 0.28 ENST00000433727.1
 BET1
 Bet1 golgi vesicular membrane trafficking protein
chr4_+_86396265 0.28 ENST00000395184.1
 ARHGAP24
 Rho GTPase activating protein 24
chr2_-_27886676 0.27 ENST00000337768.5
 SUPT7L
 suppressor of Ty 7 (S. cerevisiae)-like
chr19_+_10197463 0.27 ENST00000590378.1
ENST00000397881.3
 C19orf66
 chromosome 19 open reading frame 66
chr19_-_44809121 0.26 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
 ZNF235
 zinc finger protein 235
chr1_+_149871171 0.26 ENST00000369150.1
 BOLA1
 bolA family member 1
chr5_-_137514288 0.25 ENST00000454473.1
ENST00000418329.1
ENST00000455658.2
ENST00000230901.5
ENST00000402931.1
 BRD8
 bromodomain containing 8
chr4_+_155484103 0.25 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr19_+_37341260 0.25 ENST00000589046.1
 ZNF345
 zinc finger protein 345
chr19_+_45445491 0.24 ENST00000592954.1
ENST00000419266.2
ENST00000589057.1
 APOC4
APOC4-APOC2
 apolipoprotein C-IV
APOC4-APOC2 readthrough (NMD candidate)
chr19_+_44488330 0.24 ENST00000591532.1
ENST00000407951.2
ENST00000270014.2
ENST00000590615.1
ENST00000586454.1
 ZNF155
 zinc finger protein 155
chr7_-_26904317 0.24 ENST00000345317.2
 SKAP2
 src kinase associated phosphoprotein 2
chr5_-_137514333 0.23 ENST00000411594.2
ENST00000430331.1
 BRD8
 bromodomain containing 8
chr17_+_57784826 0.23 ENST00000262291.4
 VMP1
 vacuole membrane protein 1
chr12_-_10324716 0.23 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
 OLR1
 oxidized low density lipoprotein (lectin-like) receptor 1
chr2_-_63815628 0.22 ENST00000409562.3
 WDPCP
 WD repeat containing planar cell polarity effector
chr6_+_88182643 0.22 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
 SLC35A1
 solute carrier family 35 (CMP-sialic acid transporter), member A1
chr19_+_37341752 0.21 ENST00000586933.1
ENST00000532141.1
ENST00000420450.1
ENST00000526123.1
 ZNF345
 zinc finger protein 345
chr6_+_30130969 0.21 ENST00000376694.4
 TRIM15
 tripartite motif containing 15
chr20_-_25677465 0.21 ENST00000252979.5
 ZNF337
 zinc finger protein 337
chr5_+_178286925 0.20 ENST00000322434.3
 ZNF354B
 zinc finger protein 354B
chr8_-_146012660 0.19 ENST00000343459.4
ENST00000429371.2
ENST00000534445.1
 ZNF34
 zinc finger protein 34
chr5_-_178157700 0.19 ENST00000335815.2
 ZNF354A
 zinc finger protein 354A
chr3_-_160823158 0.19 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_-_54519134 0.19 ENST00000371341.1
 TMEM59
 transmembrane protein 59
chr3_-_160823040 0.18 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr2_-_27886460 0.18 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
 SUPT7L
 suppressor of Ty 7 (S. cerevisiae)-like
chr19_-_58220517 0.18 ENST00000512439.2
ENST00000426889.1
 ZNF154
 zinc finger protein 154
chr19_+_39881951 0.18 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
 MED29
 mediator complex subunit 29
chr19_-_36980337 0.17 ENST00000434377.2
ENST00000424129.2
ENST00000452939.1
ENST00000427002.1
 ZNF566
 zinc finger protein 566
chr19_-_50529193 0.17 ENST00000596445.1
ENST00000599538.1
 VRK3
 vaccinia related kinase 3
chr19_-_36980455 0.17 ENST00000454319.1
ENST00000392170.2
 ZNF566
 zinc finger protein 566
chr19_-_56826157 0.16 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
 ZSCAN5A
 zinc finger and SCAN domain containing 5A
chr20_-_18774614 0.16 ENST00000412553.1
 LINC00652
 long intergenic non-protein coding RNA 652
chr19_-_58427944 0.15 ENST00000312026.5
ENST00000536263.1
ENST00000598629.1
ENST00000595559.1
ENST00000597515.1
ENST00000599251.1
ENST00000598526.1
 ZNF417
 zinc finger protein 417
chr19_+_44617511 0.15 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
 ZNF225
 zinc finger protein 225
chr2_+_240684554 0.15 ENST00000407524.1
 AC093802.1
 Uncharacterized protein
chr19_+_36208877 0.14 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
 KMT2B
 Histone-lysine N-methyltransferase 2B
chr9_+_15422702 0.14 ENST00000380821.3
ENST00000421710.1
 SNAPC3
 small nuclear RNA activating complex, polypeptide 3, 50kDa
chr1_-_155112883 0.14 ENST00000368399.1
ENST00000368400.4
ENST00000341298.3
 DPM3
 dolichyl-phosphate mannosyltransferase polypeptide 3
chr11_+_2920951 0.14 ENST00000347936.2
 SLC22A18
 solute carrier family 22, member 18
chr19_+_57946684 0.14 ENST00000334181.4
ENST00000415248.1
 ZNF749
 zinc finger protein 749
chr3_-_160822858 0.14 ENST00000488170.1
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_+_67673297 0.13 ENST00000425614.1
ENST00000395227.1
 IL23R
 interleukin 23 receptor
chr1_-_54519067 0.13 ENST00000452421.1
ENST00000420738.1
ENST00000234831.5
ENST00000440019.1
 TMEM59
 transmembrane protein 59
chr1_-_16763911 0.13 ENST00000375577.1
ENST00000335496.1
 SPATA21
 spermatogenesis associated 21
chr1_+_119957554 0.13 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
 HSD3B2
 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr19_+_49404041 0.13 ENST00000263273.5
ENST00000424608.1
 NUCB1
 nucleobindin 1
chr20_+_388935 0.12 ENST00000382181.2
ENST00000400247.3
 RBCK1
 RanBP-type and C3HC4-type zinc finger containing 1
chr7_+_47834908 0.12 ENST00000418326.2
 C7orf69
 chromosome 7 open reading frame 69
chr1_-_146054494 0.12 ENST00000401009.2
 NBPF11
 neuroblastoma breakpoint family, member 11
chr1_+_53392901 0.11 ENST00000371514.3
ENST00000528311.1
ENST00000371509.4
ENST00000407246.2
ENST00000371513.5
 SCP2
 sterol carrier protein 2
chr19_-_57183114 0.11 ENST00000537055.2
ENST00000601659.1
 ZNF835
 zinc finger protein 835
chr16_-_53737795 0.11 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
 RPGRIP1L
 RPGRIP1-like
chr16_+_16434185 0.11 ENST00000524823.2
 AC138969.4
 Protein PKD1P1
chr6_-_27440837 0.11 ENST00000211936.6
 ZNF184
 zinc finger protein 184
chr8_+_27631903 0.10 ENST00000305188.8
 ESCO2
 establishment of sister chromatid cohesion N-acetyltransferase 2
chr19_+_40502938 0.10 ENST00000599504.1
ENST00000596894.1
ENST00000601138.1
ENST00000600094.1
ENST00000347077.4
 ZNF546
 zinc finger protein 546
chr19_+_58361185 0.10 ENST00000339656.5
ENST00000423137.1
 ZNF587
 zinc finger protein 587
chr5_+_178368186 0.10 ENST00000320129.3
ENST00000519564.1
 ZNF454
 zinc finger protein 454
chr11_-_71639670 0.09 ENST00000533047.1
ENST00000529844.1
 RP11-849H4.2
 Putative short transient receptor potential channel 2-like protein
chr11_-_67374177 0.09 ENST00000333139.3
 C11orf72
 chromosome 11 open reading frame 72
chr16_-_53737722 0.08 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
 RPGRIP1L
 RPGRIP1-like
chr19_+_44455368 0.08 ENST00000591168.1
ENST00000587682.1
ENST00000251269.5
 ZNF221
 zinc finger protein 221
chr8_-_109260897 0.08 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
 EIF3E
 eukaryotic translation initiation factor 3, subunit E
chr19_+_44529479 0.08 ENST00000587846.1
ENST00000187879.8
ENST00000391960.3
 ZNF222
 zinc finger protein 222
chr11_-_71639480 0.08 ENST00000529513.1
 RP11-849H4.2
 Putative short transient receptor potential channel 2-like protein
chr2_-_75426826 0.08 ENST00000305249.5
 TACR1
 tachykinin receptor 1
chr19_-_39881777 0.07 ENST00000595564.1
ENST00000221265.3
 PAF1
 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr12_+_120740119 0.07 ENST00000536460.1
ENST00000202967.4
 SIRT4
 sirtuin 4
chr19_+_44716678 0.07 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
 ZNF227
 zinc finger protein 227
chr19_+_45445524 0.06 ENST00000591600.1
 APOC4
 apolipoprotein C-IV
chr19_-_38085633 0.06 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
 ZNF571
 zinc finger protein 571
chr19_-_36980756 0.06 ENST00000493391.1
 ZNF566
 zinc finger protein 566
chr3_+_130745688 0.06 ENST00000510769.1
ENST00000429253.2
ENST00000356918.4
ENST00000510688.1
ENST00000511262.1
ENST00000383366.4
 NEK11
 NIMA-related kinase 11
chr3_-_150920979 0.06 ENST00000309180.5
ENST00000480322.1
 GPR171
 G protein-coupled receptor 171
chr20_+_34824355 0.06 ENST00000397286.3
ENST00000320849.4
ENST00000373932.3
 AAR2
 AAR2 splicing factor homolog (S. cerevisiae)
chr11_+_71640112 0.05 ENST00000530137.1
 RNF121
 ring finger protein 121
chr6_-_27440460 0.05 ENST00000377419.1
 ZNF184
 zinc finger protein 184
chr3_+_130745769 0.04 ENST00000412440.2
 NEK11
 NIMA-related kinase 11
chr14_-_20881579 0.04 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
 TEP1
 telomerase-associated protein 1
chr8_-_56685859 0.04 ENST00000523423.1
ENST00000523073.1
ENST00000519784.1
ENST00000434581.2
ENST00000519780.1
ENST00000521229.1
ENST00000522576.1
ENST00000523180.1
ENST00000522090.1
 TMEM68
 transmembrane protein 68
chr11_+_71640071 0.04 ENST00000533380.1
ENST00000393713.3
ENST00000545854.1
 RNF121
 ring finger protein 121
chr3_+_151531810 0.04 ENST00000232892.7
 AADAC
 arylacetamide deacetylase
chr6_+_30131318 0.03 ENST00000376688.1
 TRIM15
 tripartite motif containing 15
chr20_+_39657454 0.03 ENST00000361337.2
 TOP1
 topoisomerase (DNA) I
chr19_-_44439387 0.03 ENST00000269973.5
 ZNF45
 zinc finger protein 45
chr12_-_110883346 0.03 ENST00000547365.1
 ARPC3
 actin related protein 2/3 complex, subunit 3, 21kDa
chr3_-_130745571 0.03 ENST00000514044.1
ENST00000264992.3
 ASTE1
 asteroid homolog 1 (Drosophila)
chrX_-_70474910 0.02 ENST00000373988.1
ENST00000373998.1
 ZMYM3
 zinc finger, MYM-type 3
chr4_+_40194609 0.02 ENST00000508513.1
 RHOH
 ras homolog family member H
chr7_-_108096822 0.01 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
 NRCAM
 neuronal cell adhesion molecule
chr7_+_47834880 0.01 ENST00000258776.4
 C7orf69
 chromosome 7 open reading frame 69
chr19_-_40023450 0.01 ENST00000326282.4
 EID2B
 EP300 interacting inhibitor of differentiation 2B
chr8_-_56685966 0.01 ENST00000334667.2
 TMEM68
 transmembrane protein 68
chr2_+_27886330 0.01 ENST00000326019.6
 SLC4A1AP
 solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr2_+_17721230 0.00 ENST00000457525.1
 VSNL1
 visinin-like 1

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.9 GO:0008940 nitrate reductase activity(GO:0008940)
0.2 2.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.2 0.5 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 4.3 GO:0019843 rRNA binding(GO:0019843)
0.1 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004769 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1 0.9 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 1.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.3 GO:0046102 hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102)
0.1 2.0 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.3 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.4 GO:0015886 heme transport(GO:0015886) xenobiotic transport(GO:0042908)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 4.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.7 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 4.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 6.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 4.3 GO:0005844 polysome(GO:0005844)
0.1 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0044447 axoneme part(GO:0044447)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)