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ENCODE cell lines, expression (Ernst 2011)

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Results for STAT6

Z-value: 1.17

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
STAT6
ENSG00000166888.6 STAT6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg19_v2_chr12_-_57505121_575052160.656.2e-03Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_158991025 4.05 ENST00000337808.6
 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
chr21_+_42539701 4.02 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
 BACE2
 beta-site APP-cleaving enzyme 2
chr5_+_102201722 3.95 ENST00000274392.9
ENST00000455264.2
 PAM
 peptidylglycine alpha-amidating monooxygenase
chr3_+_158787041 3.94 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
chr1_-_68299130 3.21 ENST00000370982.3
 GNG12
 guanine nucleotide binding protein (G protein), gamma 12
chrX_+_135251783 2.87 ENST00000394153.2
 FHL1
 four and a half LIM domains 1
chr2_-_190044480 2.85 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr5_+_102201687 2.30 ENST00000304400.7
 PAM
 peptidylglycine alpha-amidating monooxygenase
chrX_+_135252050 2.06 ENST00000449474.1
ENST00000345434.3
 FHL1
 four and a half LIM domains 1
chr1_+_150245177 1.84 ENST00000369098.3
 C1orf54
 chromosome 1 open reading frame 54
chr11_-_14379997 1.75 ENST00000526063.1
ENST00000532814.1
 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
chr13_+_73629107 1.67 ENST00000539231.1
 KLF5
 Kruppel-like factor 5 (intestinal)
chrX_+_135251835 1.62 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr17_+_32582293 1.56 ENST00000580907.1
ENST00000225831.4
 CCL2
 chemokine (C-C motif) ligand 2
chr14_-_23285011 1.55 ENST00000397532.3
 SLC7A7
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr15_+_25200074 1.55 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
 SNRPN
 small nuclear ribonucleoprotein polypeptide N
chr14_-_23285069 1.53 ENST00000554758.1
ENST00000397528.4
 SLC7A7
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_150245099 1.51 ENST00000369099.3
 C1orf54
 chromosome 1 open reading frame 54
chr15_+_25200108 1.48 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
 SNURF
SNRPN
 SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr7_-_15726296 1.44 ENST00000262041.5
 MEOX2
 mesenchyme homeobox 2
chr15_-_23932437 1.30 ENST00000331837.4
 NDN
 necdin, melanoma antigen (MAGE) family member
chr20_-_23066953 1.26 ENST00000246006.4
 CD93
 CD93 molecule
chrX_-_106960285 1.25 ENST00000503515.1
ENST00000372397.2
 TSC22D3
 TSC22 domain family, member 3
chr14_-_69446034 1.20 ENST00000193403.6
 ACTN1
 actinin, alpha 1
chr22_+_44464923 1.17 ENST00000404989.1
 PARVB
 parvin, beta
chr8_+_104311059 1.14 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
 FZD6
 frizzled family receptor 6
chr3_-_73673991 1.12 ENST00000308537.4
ENST00000263666.4
 PDZRN3
 PDZ domain containing ring finger 3
chr4_-_186877806 1.11 ENST00000355634.5
 SORBS2
 sorbin and SH3 domain containing 2
chrX_+_100878079 1.11 ENST00000471229.2
 ARMCX3
 armadillo repeat containing, X-linked 3
chr11_+_77532233 1.07 ENST00000525409.1
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr5_+_35856951 1.06 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
 IL7R
 interleukin 7 receptor
chr4_+_30721968 1.02 ENST00000361762.2
 PCDH7
 protocadherin 7
chr6_-_11232891 0.99 ENST00000379433.5
ENST00000379446.5
 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
chr2_-_16804320 0.97 ENST00000355549.2
 FAM49A
 family with sequence similarity 49, member A
chr2_+_120124497 0.97 ENST00000355857.3
ENST00000535617.1
ENST00000535757.1
ENST00000409094.1
ENST00000311521.4
 DBI
 diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr2_-_133427767 0.96 ENST00000397463.2
 LYPD1
 LY6/PLAUR domain containing 1
chr8_+_9953061 0.90 ENST00000522907.1
ENST00000528246.1
 MSRA
 methionine sulfoxide reductase A
chr8_+_9953214 0.85 ENST00000382490.5
 MSRA
 methionine sulfoxide reductase A
chr10_-_101769617 0.84 ENST00000324109.4
ENST00000342239.3
 DNMBP
 dynamin binding protein
chr2_+_191792376 0.84 ENST00000409428.1
ENST00000409215.1
 GLS
 glutaminase
chr19_+_15218180 0.79 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
 SYDE1
 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr9_-_13175823 0.77 ENST00000545857.1
 MPDZ
 multiple PDZ domain protein
chr11_+_77532155 0.76 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr11_+_65082289 0.75 ENST00000279249.2
 CDC42EP2
 CDC42 effector protein (Rho GTPase binding) 2
chr12_-_71031185 0.73 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr14_+_55034599 0.69 ENST00000392067.3
ENST00000357634.3
 SAMD4A
 sterile alpha motif domain containing 4A
chr2_-_202316260 0.68 ENST00000332624.3
 TRAK2
 trafficking protein, kinesin binding 2
chr3_+_179370517 0.62 ENST00000263966.3
 USP13
 ubiquitin specific peptidase 13 (isopeptidase T-3)
chr8_+_97506033 0.61 ENST00000518385.1
 SDC2
 syndecan 2
chr6_-_24877490 0.54 ENST00000540914.1
ENST00000378023.4
 FAM65B
 family with sequence similarity 65, member B
chr12_+_12764773 0.49 ENST00000228865.2
 CREBL2
 cAMP responsive element binding protein-like 2
chr17_+_40912764 0.49 ENST00000589683.1
ENST00000588928.1
 RAMP2
 receptor (G protein-coupled) activity modifying protein 2
chr12_-_71031220 0.44 ENST00000334414.6
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr2_-_230786619 0.44 ENST00000389045.3
ENST00000409677.1
 TRIP12
 thyroid hormone receptor interactor 12
chr1_-_108735440 0.42 ENST00000370041.4
 SLC25A24
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr11_+_118230287 0.42 ENST00000252108.3
ENST00000431736.2
 UBE4A
 ubiquitination factor E4A
chr12_-_111358372 0.40 ENST00000548438.1
ENST00000228841.8
 MYL2
 myosin, light chain 2, regulatory, cardiac, slow
chr11_+_112832202 0.37 ENST00000534015.1
 NCAM1
 neural cell adhesion molecule 1
chr12_-_6451235 0.36 ENST00000440083.2
ENST00000162749.2
 TNFRSF1A
 tumor necrosis factor receptor superfamily, member 1A
chr17_+_68071389 0.35 ENST00000283936.1
ENST00000392671.1
 KCNJ16
 potassium inwardly-rectifying channel, subfamily J, member 16
chr9_+_90112741 0.33 ENST00000469640.2
 DAPK1
 death-associated protein kinase 1
chr22_-_42342733 0.33 ENST00000402420.1
 CENPM
 centromere protein M
chr11_+_112832133 0.33 ENST00000524665.1
 NCAM1
 neural cell adhesion molecule 1
chr9_+_90112767 0.32 ENST00000408954.3
 DAPK1
 death-associated protein kinase 1
chr17_+_44588877 0.31 ENST00000576629.1
 LRRC37A2
 leucine rich repeat containing 37, member A2
chr11_-_67980744 0.31 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
 SUV420H1
 suppressor of variegation 4-20 homolog 1 (Drosophila)
chr14_+_56127989 0.27 ENST00000555573.1
 KTN1
 kinectin 1 (kinesin receptor)
chr9_+_90112590 0.26 ENST00000472284.1
 DAPK1
 death-associated protein kinase 1
chr22_+_38201114 0.26 ENST00000340857.2
 H1F0
 H1 histone family, member 0
chr12_+_26164645 0.25 ENST00000542004.1
 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr10_-_65028817 0.24 ENST00000542921.1
 JMJD1C
 jumonji domain containing 1C
chr20_-_18477862 0.24 ENST00000337227.4
 RBBP9
 retinoblastoma binding protein 9
chr1_+_89246647 0.23 ENST00000544045.1
 PKN2
 protein kinase N2
chr6_+_26440700 0.23 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
 BTN3A3
 butyrophilin, subfamily 3, member A3
chr2_-_175462456 0.22 ENST00000409891.1
ENST00000410117.1
 WIPF1
 WAS/WASL interacting protein family, member 1
chr11_+_112832090 0.22 ENST00000533760.1
 NCAM1
 neural cell adhesion molecule 1
chr2_+_182756615 0.20 ENST00000431877.2
ENST00000320370.7
 SSFA2
 sperm specific antigen 2
chr1_-_94586651 0.19 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr1_-_241803679 0.18 ENST00000331838.5
 OPN3
 opsin 3
chr9_+_90112117 0.17 ENST00000358077.5
 DAPK1
 death-associated protein kinase 1
chr4_-_10686475 0.17 ENST00000226951.6
 CLNK
 cytokine-dependent hematopoietic cell linker
chr6_-_32821599 0.17 ENST00000354258.4
 TAP1
 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chrX_-_72434628 0.16 ENST00000536638.1
ENST00000373517.3
 NAP1L2
 nucleosome assembly protein 1-like 2
chr1_-_201915590 0.15 ENST00000367288.4
 LMOD1
 leiomodin 1 (smooth muscle)
chr12_+_123949053 0.14 ENST00000350887.5
 SNRNP35
 small nuclear ribonucleoprotein 35kDa (U11/U12)
chr2_-_26700900 0.14 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
 OTOF
 otoferlin
chr8_-_82359662 0.14 ENST00000519260.1
ENST00000256103.2
 PMP2
 peripheral myelin protein 2
chr5_+_112227311 0.13 ENST00000391338.1
 ZRSR1
 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
chr12_+_6493199 0.13 ENST00000228918.4
 LTBR
 lymphotoxin beta receptor (TNFR superfamily, member 3)
chr22_-_29457832 0.13 ENST00000216071.4
 C22orf31
 chromosome 22 open reading frame 31
chr11_-_10828892 0.13 ENST00000525681.1
 EIF4G2
 eukaryotic translation initiation factor 4 gamma, 2
chr5_+_74011328 0.12 ENST00000513336.1
 HEXB
 hexosaminidase B (beta polypeptide)
chr7_-_122840015 0.12 ENST00000194130.2
 SLC13A1
 solute carrier family 13 (sodium/sulfate symporter), member 1
chr15_+_96869165 0.12 ENST00000421109.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr12_+_56435637 0.12 ENST00000356464.5
ENST00000552361.1
 RPS26
 ribosomal protein S26
chr15_+_27111510 0.11 ENST00000335625.5
 GABRA5
 gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr6_-_27880174 0.11 ENST00000303324.2
 OR2B2
 olfactory receptor, family 2, subfamily B, member 2
chr9_+_36572851 0.10 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
 MELK
 maternal embryonic leucine zipper kinase
chr7_-_76829125 0.09 ENST00000248598.5
 FGL2
 fibrinogen-like 2
chr8_+_123793633 0.09 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr20_+_57209828 0.08 ENST00000598340.1
 MGC4294
 HCG1785561; MGC4294 protein; Uncharacterized protein
chr7_-_150777920 0.08 ENST00000353841.2
ENST00000297532.6
 FASTK
 Fas-activated serine/threonine kinase
chr6_+_32821924 0.08 ENST00000374859.2
ENST00000453265.2
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr14_+_22386325 0.07 ENST00000390439.2
 TRAV13-2
 T cell receptor alpha variable 13-2
chr11_-_60719213 0.07 ENST00000227880.3
 SLC15A3
 solute carrier family 15 (oligopeptide transporter), member 3
chr4_+_95972822 0.07 ENST00000509540.1
ENST00000440890.2
 BMPR1B
 bone morphogenetic protein receptor, type IB
chr19_+_15052301 0.07 ENST00000248072.3
 OR7C2
 olfactory receptor, family 7, subfamily C, member 2
chr13_-_45915221 0.06 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
 TPT1
 tumor protein, translationally-controlled 1
chr19_+_38924316 0.06 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
 RYR1
 ryanodine receptor 1 (skeletal)
chr12_-_10151773 0.06 ENST00000298527.6
ENST00000348658.4
 CLEC1B
 C-type lectin domain family 1, member B
chr22_+_32439019 0.06 ENST00000266088.4
 SLC5A1
 solute carrier family 5 (sodium/glucose cotransporter), member 1
chr7_-_150777949 0.05 ENST00000482571.1
 FASTK
 Fas-activated serine/threonine kinase
chr11_+_118175132 0.05 ENST00000361763.4
 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
chr3_-_49851313 0.04 ENST00000333486.3
 UBA7
 ubiquitin-like modifier activating enzyme 7
chr17_+_7461781 0.04 ENST00000349228.4
 TNFSF13
 tumor necrosis factor (ligand) superfamily, member 13
chr11_-_77531858 0.03 ENST00000360355.2
 RSF1
 remodeling and spacing factor 1
chr12_+_9144626 0.03 ENST00000543895.1
 KLRG1
 killer cell lectin-like receptor subfamily G, member 1
chr16_+_67694849 0.03 ENST00000602551.1
ENST00000458121.2
ENST00000219255.3
 PARD6A
 par-6 family cell polarity regulator alpha
chr3_+_121311966 0.02 ENST00000338040.4
 FBXO40
 F-box protein 40
chr5_+_140602904 0.02 ENST00000515856.2
ENST00000239449.4
 PCDHB14
 protocadherin beta 14
chr15_+_89402148 0.01 ENST00000560601.1
 ACAN
 aggrecan
chr14_+_38677123 0.01 ENST00000267377.2
 SSTR1
 somatostatin receptor 1
chr1_-_116383738 0.00 ENST00000320238.3
 NHLH2
 nescient helix loop helix 2
chr1_+_152691998 0.00 ENST00000368775.2
 C1orf68
 chromosome 1 open reading frame 68
chr1_+_174417095 0.00 ENST00000367685.2
 GPR52
 G protein-coupled receptor 52

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.0 GO:0005687 U4 snRNP(GO:0005687)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 3.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 7.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 2.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 11.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.7 2.8 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.5 1.6 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.5 3.1 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.5 4.0 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.4 1.4 GO:0001757 somite specification(GO:0001757)
0.3 1.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.7 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 0.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.7 GO:0030091 protein repair(GO:0030091)
0.2 1.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 0.8 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 1.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.6 GO:0035523 protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 6.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 1.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.2 GO:0002456 T cell mediated immunity(GO:0002456)
0.1 0.4 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1 3.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.5 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 1.3 GO:0003016 respiratory system process(GO:0003016)
0.0 1.0 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.4 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 2.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.3 GO:0042116 macrophage activation(GO:0042116)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5 1.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 1.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.3 1.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 3.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.3 3.2 GO:0042301 phosphate ion binding(GO:0042301)
0.2 0.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 4.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 1.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.3 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.5 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.4 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.0 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 1.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 6.6 GO:0044325 ion channel binding(GO:0044325)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)