ISMARA results: T

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ENCODE cell lines, expression (Ernst 2011)

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Results for T

Z-value: 0.71

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Transcription factors associated with T

Gene Symbol	Gene ID	Gene Info
T Ensembl NCBI GeneCards UniProt	ENSG00000164458.5	T

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
T	hg19_v2_chr6_-_166582107_166582188	-0.39	1.3e-01	Click!

Activity profile of T motif

Sorted Z-values of T motif

Network of associatons between targets according to the STRING database.

First level regulatory network of T

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr12_-_52845910	2.29	ENST00000252252.3	KRT6B	keratin 6B
chr10_-_5060201	1.61	ENST00000407674.1	AKR1C2	aldo-keto reductase family 1, member C2
chr12_-_52867569	1.48	ENST00000252250.6	KRT6C	keratin 6C
chr10_-_5060147	1.39	ENST00000604507.1	AKR1C2	aldo-keto reductase family 1, member C2
chr19_-_6690723	1.34	ENST00000601008.1	C3	complement component 3
chr3_+_142315225	1.08	ENST00000457734.2 ENST00000483373.1 ENST00000475296.1 ENST00000495744.1 ENST00000476044.1 ENST00000461644.1	PLS1	plastin 1
chr12_+_19358228	0.95	ENST00000424268.1 ENST00000543806.1	PLEKHA5	pleckstrin homology domain containing, family A member 5
chr2_+_234601512	0.91	ENST00000305139.6	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6
chr10_+_5488564	0.83	ENST00000449083.1 ENST00000380359.3	NET1	neuroepithelial cell transforming 1
chr1_-_24126023	0.82	ENST00000429356.1	GALE	UDP-galactose-4-epimerase
chr12_-_53074182	0.82	ENST00000252244.3	KRT1	keratin 1
chr1_-_153029980	0.60	ENST00000392653.2	SPRR2A	small proline-rich protein 2A
chr5_+_50678921	0.59	ENST00000230658.7	ISL1	ISL LIM homeobox 1
chr6_+_83073334	0.58	ENST00000369750.3	TPBG	trophoblast glycoprotein
chr2_-_200322723	0.48	ENST00000417098.1	SATB2	SATB homeobox 2
chr14_+_95078714	0.48	ENST00000393078.3 ENST00000393080.4 ENST00000467132.1	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr4_-_73434498	0.48	ENST00000286657.4	ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr20_-_60942361	0.46	ENST00000252999.3	LAMA5	laminin, alpha 5
chr1_-_153066998	0.46	ENST00000368750.3	SPRR2E	small proline-rich protein 2E
chr2_-_219031709	0.43	ENST00000295683.2	CXCR1	chemokine (C-X-C motif) receptor 1
chr7_-_76255444	0.43	ENST00000454397.1	POMZP3	POM121 and ZP3 fusion
chr6_-_26124138	0.43	ENST00000314332.5 ENST00000396984.1	HIST1H2BC	histone cluster 1, H2bc
chr17_+_72427477	0.40	ENST00000342648.5 ENST00000481232.1	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr2_-_85636928	0.37	ENST00000449030.1	CAPG	capping protein (actin filament), gelsolin-like
chr21_-_45078019	0.37	ENST00000542962.1	HSF2BP	heat shock transcription factor 2 binding protein
chr2_+_120687335	0.35	ENST00000544261.1	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr14_+_75746781	0.35	ENST00000555347.1	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr3_-_126373929	0.33	ENST00000523403.1 ENST00000524230.2	TXNRD3	thioredoxin reductase 3
chr19_-_36297348	0.33	ENST00000589835.1	PRODH2	proline dehydrogenase (oxidase) 2
chr11_-_66112555	0.32	ENST00000425825.2 ENST00000359957.3	BRMS1	breast cancer metastasis suppressor 1
chrX_+_16804544	0.32	ENST00000380122.5 ENST00000398155.4	TXLNG	taxilin gamma
chr15_+_40861487	0.30	ENST00000315616.7 ENST00000559271.1	RPUSD2	RNA pseudouridylate synthase domain containing 2
chr20_+_32951041	0.29	ENST00000374864.4	ITCH	itchy E3 ubiquitin protein ligase
chr4_-_140005443	0.28	ENST00000510408.1 ENST00000420916.2 ENST00000358635.3	ELF2	E74-like factor 2 (ets domain transcription factor)
chr20_+_32951070	0.28	ENST00000535650.1 ENST00000262650.6	ITCH	itchy E3 ubiquitin protein ligase
chrX_-_48216101	0.26	ENST00000298396.2 ENST00000376893.3	SSX3	synovial sarcoma, X breakpoint 3
chr2_+_108905325	0.26	ENST00000438339.1 ENST00000409880.1 ENST00000437390.2	SULT1C2	sulfotransferase family, cytosolic, 1C, member 2
chr6_+_26158343	0.26	ENST00000377777.4 ENST00000289316.2	HIST1H2BD	histone cluster 1, H2bd
chr2_-_152118352	0.25	ENST00000331426.5	RBM43	RNA binding motif protein 43
chr1_+_15272271	0.25	ENST00000400797.3	KAZN	kazrin, periplakin interacting protein
chr3_-_52443799	0.25	ENST00000470173.1 ENST00000296288.5	BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr16_+_69458537	0.25	ENST00000515314.1 ENST00000561792.1 ENST00000568237.1	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)
chr1_+_39456895	0.23	ENST00000432648.3 ENST00000446189.2 ENST00000372984.4	AKIRIN1	akirin 1
chr15_-_34502278	0.23	ENST00000559515.1 ENST00000256544.3 ENST00000560108.1 ENST00000559462.1	KATNBL1	katanin p80 subunit B-like 1
chr3_+_167453493	0.22	ENST00000295777.5 ENST00000472747.2	SERPINI1	serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_108905095	0.22	ENST00000251481.6 ENST00000326853.5	SULT1C2	sulfotransferase family, cytosolic, 1C, member 2
chr17_-_19281203	0.22	ENST00000487415.2	B9D1	B9 protein domain 1
chrX_+_109245863	0.22	ENST00000372072.3	TMEM164	transmembrane protein 164
chr8_-_99954788	0.21	ENST00000523601.1	STK3	serine/threonine kinase 3
chr7_+_134576317	0.21	ENST00000424922.1 ENST00000495522.1	CALD1	caldesmon 1
chr12_+_54378923	0.21	ENST00000303460.4	HOXC10	homeobox C10
chr7_+_107110488	0.20	ENST00000304402.4	GPR22	G protein-coupled receptor 22
chr8_-_141810634	0.20	ENST00000521986.1 ENST00000523539.1 ENST00000538769.1	PTK2	protein tyrosine kinase 2
chr2_-_39664405	0.19	ENST00000341681.5 ENST00000263881.3	MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3
chr6_+_43149903	0.19	ENST00000252050.4 ENST00000354495.3 ENST00000372647.2	CUL9	cullin 9
chr1_-_205290865	0.19	ENST00000367157.3	NUAK2	NUAK family, SNF1-like kinase, 2
chr17_+_17942594	0.18	ENST00000268719.4	GID4	GID complex subunit 4
chr3_+_38307293	0.17	ENST00000311856.4	SLC22A13	solute carrier family 22 (organic anion/urate transporter), member 13
chr7_+_110731062	0.17	ENST00000308478.5 ENST00000451085.1 ENST00000422987.3 ENST00000421101.1	LRRN3	leucine rich repeat neuronal 3
chr11_-_85779971	0.16	ENST00000393346.3	PICALM	phosphatidylinositol binding clathrin assembly protein
chr10_-_115423792	0.16	ENST00000369360.3 ENST00000360478.3 ENST00000359988.3 ENST00000369358.4	NRAP	nebulin-related anchoring protein
chr17_-_40306934	0.16	ENST00000592574.1 ENST00000550406.1 ENST00000547517.1 ENST00000393860.3 ENST00000346213.4	CTD-2132N18.3 RAB5C	Uncharacterized protein RAB5C, member RAS oncogene family
chr9_-_14722715	0.16	ENST00000380911.3	CER1	cerberus 1, DAN family BMP antagonist
chr15_-_83621435	0.15	ENST00000450735.2 ENST00000426485.1 ENST00000399166.2 ENST00000304231.8	HOMER2	homer homolog 2 (Drosophila)
chr4_-_69817481	0.15	ENST00000251566.4	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr19_-_1021113	0.15	ENST00000333175.5 ENST00000356663.3	TMEM259	transmembrane protein 259
chr20_+_1115821	0.14	ENST00000435720.1	PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr14_-_107211459	0.13	ENST00000390636.2	IGHV3-73	immunoglobulin heavy variable 3-73
chr11_+_64073699	0.13	ENST00000405666.1 ENST00000468670.1	ESRRA	estrogen-related receptor alpha
chr1_+_89150245	0.13	ENST00000370513.5	PKN2	protein kinase N2
chr20_+_44637526	0.12	ENST00000372330.3	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr17_-_61523622	0.12	ENST00000448884.2 ENST00000582297.1 ENST00000582034.1 ENST00000578072.1 ENST00000360793.3	CYB561	cytochrome b561
chr16_-_2314222	0.12	ENST00000566397.1	RNPS1	RNA binding protein S1, serine-rich domain
chr11_-_236326	0.11	ENST00000525237.1 ENST00000532956.1 ENST00000525319.1 ENST00000524564.1 ENST00000382743.4	SIRT3	sirtuin 3
chr17_-_56084578	0.11	ENST00000582730.2 ENST00000584773.1 ENST00000585096.1 ENST00000258962.4	SRSF1	serine/arginine-rich splicing factor 1
chr6_-_106773291	0.11	ENST00000343245.3	ATG5	autophagy related 5
chr1_-_45452240	0.10	ENST00000372183.3 ENST00000372182.4 ENST00000360403.2	EIF2B3	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
chr2_-_208030647	0.10	ENST00000309446.6	KLF7	Kruppel-like factor 7 (ubiquitous)
chr6_-_106773610	0.10	ENST00000369076.3 ENST00000369070.1	ATG5	autophagy related 5
chr5_-_131330272	0.10	ENST00000379240.1	ACSL6	acyl-CoA synthetase long-chain family member 6
chr17_+_17942684	0.10	ENST00000376345.3	GID4	GID complex subunit 4
chr6_+_29079668	0.09	ENST00000377169.1	OR2J3	olfactory receptor, family 2, subfamily J, member 3
chr5_-_137610300	0.09	ENST00000274721.3	GFRA3	GDNF family receptor alpha 3
chr13_+_53602894	0.09	ENST00000219022.2	OLFM4	olfactomedin 4
chr1_+_27648648	0.09	ENST00000374076.4	TMEM222	transmembrane protein 222
chr2_-_241737128	0.09	ENST00000404283.3	KIF1A	kinesin family member 1A
chr1_+_27648709	0.09	ENST00000608611.1 ENST00000466759.1 ENST00000464813.1 ENST00000498220.1	TMEM222	transmembrane protein 222
chr1_+_89149905	0.08	ENST00000316005.7 ENST00000370521.3 ENST00000370505.3	PKN2	protein kinase N2
chr22_-_36031181	0.08	ENST00000594060.1	AL049747.1	AL049747.1
chr5_-_137610254	0.08	ENST00000378362.3	GFRA3	GDNF family receptor alpha 3
chr20_+_1093891	0.08	ENST00000333082.3 ENST00000381898.4 ENST00000381899.4	PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr14_+_96722539	0.08	ENST00000553356.1	BDKRB1	bradykinin receptor B1
chr2_-_103353277	0.07	ENST00000258436.5	MFSD9	major facilitator superfamily domain containing 9
chr5_-_131329918	0.07	ENST00000357096.1 ENST00000431707.1 ENST00000434099.1	ACSL6	acyl-CoA synthetase long-chain family member 6
chr19_+_3721719	0.07	ENST00000589378.1 ENST00000382008.3	TJP3	tight junction protein 3
chr12_-_69326940	0.07	ENST00000549781.1 ENST00000548262.1 ENST00000551568.1 ENST00000548954.1	CPM	carboxypeptidase M
chr10_+_51565188	0.07	ENST00000430396.2 ENST00000374087.4 ENST00000414907.2	NCOA4	nuclear receptor coactivator 4
chr19_-_17958832	0.07	ENST00000458235.1	JAK3	Janus kinase 3
chr2_+_233320827	0.07	ENST00000295463.3	ALPI	alkaline phosphatase, intestinal
chr1_-_13052998	0.07	ENST00000436041.1	WI2-3308P17.2	Uncharacterized protein
chr12_+_14572070	0.06	ENST00000545769.1 ENST00000428217.2 ENST00000396279.2 ENST00000542514.1 ENST00000536279.1	ATF7IP	activating transcription factor 7 interacting protein
chr1_-_211752073	0.06	ENST00000367001.4	SLC30A1	solute carrier family 30 (zinc transporter), member 1
chr10_-_79789291	0.06	ENST00000372371.3	POLR3A	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr2_+_102759199	0.05	ENST00000409288.1 ENST00000410023.1	IL1R1	interleukin 1 receptor, type I
chr19_-_17958771	0.05	ENST00000534444.1	JAK3	Janus kinase 3
chr3_-_52002403	0.05	ENST00000490063.1 ENST00000468324.1 ENST00000497653.1 ENST00000484633.1	PCBP4	poly(rC) binding protein 4
chr2_-_27341966	0.05	ENST00000402394.1 ENST00000402550.1 ENST00000260595.5	CGREF1	cell growth regulator with EF-hand domain 1
chr3_+_133502877	0.04	ENST00000466490.2	SRPRB	signal recognition particle receptor, B subunit
chr9_+_131452239	0.04	ENST00000372688.4 ENST00000372686.5	SET	SET nuclear oncogene
chr1_-_204135450	0.04	ENST00000272190.8 ENST00000367195.2	REN	renin
chr1_+_114471809	0.04	ENST00000426820.2	HIPK1	homeodomain interacting protein kinase 1
chr12_-_56709674	0.04	ENST00000551286.1 ENST00000549318.1	CNPY2 RP11-977G19.10	canopy FGF signaling regulator 2 Uncharacterized protein
chr2_-_216003127	0.04	ENST00000412081.1 ENST00000272895.7	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr2_+_122494676	0.04	ENST00000455432.1	TSN	translin
chr1_+_158325684	0.03	ENST00000368162.2	CD1E	CD1e molecule
chr3_-_57678772	0.03	ENST00000311128.5	DENND6A	DENN/MADD domain containing 6A
chr22_-_41215291	0.03	ENST00000542412.1 ENST00000544408.1	SLC25A17	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr12_-_49351303	0.03	ENST00000256682.4	ARF3	ADP-ribosylation factor 3
chrX_+_100663243	0.03	ENST00000316594.5	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr1_-_115124257	0.03	ENST00000369541.3	BCAS2	breast carcinoma amplified sequence 2
chr1_+_114472481	0.03	ENST00000369555.2	HIPK1	homeodomain interacting protein kinase 1
chr21_-_27107283	0.03	ENST00000284971.3 ENST00000400099.1	ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr21_-_27107344	0.03	ENST00000457143.2	ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr17_+_57970469	0.03	ENST00000443572.2 ENST00000406116.3 ENST00000225577.4 ENST00000393021.3	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr7_-_142176790	0.03	ENST00000390369.2	TRBV7-4	T cell receptor beta variable 7-4 (gene/pseudogene)
chr17_-_17942473	0.03	ENST00000585101.1 ENST00000474627.3 ENST00000444058.1	ATPAF2	ATP synthase mitochondrial F1 complex assembly factor 2
chr22_+_19929130	0.03	ENST00000361682.6 ENST00000403184.1 ENST00000403710.1 ENST00000407537.1	COMT	catechol-O-methyltransferase
chr19_+_55235969	0.03	ENST00000402254.2 ENST00000538269.1 ENST00000541392.1 ENST00000291860.1 ENST00000396284.2	KIR3DL1 KIR3DL3 KIR2DL4	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr21_+_27107672	0.02	ENST00000400075.3	GABPA	GA binding protein transcription factor, alpha subunit 60kDa
chr2_+_176972000	0.02	ENST00000249504.5	HOXD11	homeobox D11
chr5_+_54320078	0.02	ENST00000231009.2	GZMK	granzyme K (granzyme 3; tryptase II)
chr21_-_27107198	0.02	ENST00000400094.1	ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr2_+_166152283	0.02	ENST00000375427.2	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr9_+_36572851	0.02	ENST00000298048.2 ENST00000538311.1 ENST00000536987.1 ENST00000545008.1 ENST00000536860.1 ENST00000536329.1 ENST00000541717.1 ENST00000543751.1	MELK	maternal embryonic leucine zipper kinase
chr11_-_64889252	0.02	ENST00000525297.1 ENST00000529259.1	FAU	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr7_-_752577	0.02	ENST00000544935.1 ENST00000430040.1 ENST00000456696.2 ENST00000406797.1	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr4_+_128554081	0.02	ENST00000335251.6 ENST00000296461.5	INTU	inturned planar cell polarity protein
chr2_-_85895295	0.01	ENST00000428225.1 ENST00000519937.2	SFTPB	surfactant protein B
chr1_-_224517823	0.01	ENST00000469968.1 ENST00000436927.1 ENST00000469075.1 ENST00000488718.1 ENST00000482491.1 ENST00000340871.4 ENST00000492281.1 ENST00000361463.3 ENST00000391875.2 ENST00000461546.1	NVL	nuclear VCP-like
chr20_+_3190006	0.01	ENST00000380113.3 ENST00000455664.2 ENST00000399838.3	ITPA	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr15_-_83474806	0.01	ENST00000541889.1 ENST00000334574.8 ENST00000561368.1	FSD2	fibronectin type III and SPRY domain containing 2
chr1_+_114472222	0.01	ENST00000369558.1 ENST00000369561.4	HIPK1	homeodomain interacting protein kinase 1
chr12_-_56710118	0.01	ENST00000273308.4	CNPY2	canopy FGF signaling regulator 2
chr17_+_26662597	0.00	ENST00000544907.2	TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr6_-_29013017	0.00	ENST00000377175.1	OR2W1	olfactory receptor, family 2, subfamily W, member 1
chr3_-_66551351	0.00	ENST00000273261.3	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
chr3_+_137728842	0.00	ENST00000183605.5	CLDN18	claudin 18

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	6.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.7	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.7	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	1.5	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	1.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	3.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	3.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.6	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	0.6	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	1.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	6.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	1.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	1.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	2.0	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.0	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.6	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	2.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	3.0	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	1.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	1.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	5.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.6	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.6	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	1.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.1	1.7	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	1.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.4	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	1.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.8	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	1.7	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	2.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.9	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	2.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.9	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	4.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	4.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	3.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	2.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	6.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	2.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	3.6	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	2.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	5.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	1.0	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	1.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.9	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	2.2	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	2.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	0.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	1.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	2.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	3.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	2.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	1.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.3	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	1.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	1.6	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	3.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.8	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	6.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	4.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.7	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.8	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	3.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	0.8	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.8	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.8	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	5.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.8	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	1.5	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	1.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	2.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	1.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	3.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	1.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	1.4	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	1.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.4	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.2	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.5	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	24.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.6	6.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	28.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.4	25.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	4.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	2.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	4.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	1.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	2.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	2.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	1.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	1.5	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	2.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	2.7	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.1	11.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	5.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	2.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	0.7	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	1.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	4.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	1.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	1.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.0	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	1.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.4	11.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4	1.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.4	27.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.4	10.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.4	4.0	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.4	1.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.3	3.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.3	5.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	6.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	17.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	4.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	1.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	6.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	3.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2	9.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.2	5.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	7.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	8.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	3.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	2.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	2.9	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.2	4.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	5.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	2.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	7.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	2.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.2	5.1	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.2	5.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	0.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.2	1.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	2.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	2.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	3.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.3	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.1	1.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.1	1.0	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	1.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	3.8	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	6.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	1.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	3.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	2.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	1.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	2.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	12.4	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.1	1.8	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	2.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	3.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	2.9	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	3.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	0.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.1	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	1.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.1	0.9	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	1.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	0.9	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	2.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	8.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.9	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	2.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	1.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	1.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.8	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	1.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	1.5	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	0.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	3.7	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	0.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	3.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	1.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	3.2	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.9	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	2.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.4	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.5	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.4	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	3.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	3.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	3.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.3	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.5	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.1	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.7	2.0	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4	1.4	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.3	2.3	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	8.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3	1.6	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.3	3.5	GO:0008517	folic acid transporter activity(GO:0008517)
0.3	1.3	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.2	3.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	0.7	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.2	1.3	GO:0045569	TRAIL binding(GO:0045569)
0.2	0.6	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.2	1.8	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	5.8	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.5	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	0.7	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	0.2	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.5	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.9	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1	0.9	GO:0034452	dynactin binding(GO:0034452)
0.1	0.8	GO:0051434	BH3 domain binding(GO:0051434)
0.1	1.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	0.3	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.8	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	1.3	GO:0031005	filamin binding(GO:0031005)
0.1	2.1	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1	0.5	GO:0043426	MRF binding(GO:0043426)
0.1	0.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	0.3	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.4	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.8	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.8	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	2.2	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.1	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.0	0.5	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.0	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	8.7	GO:0051015	actin filament binding(GO:0051015)
0.0	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.7	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.6	GO:0000339	RNA cap binding(GO:0000339)
0.0	1.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.6	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.6	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.4	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.4	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.8	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	4.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.2	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	1.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.7	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.4	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	1.4	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	2.0	GO:0019838	growth factor binding(GO:0019838)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	1.7	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.5	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.9	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	0.8	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.6	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.7	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	12.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.6	8.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.6	19.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.6	21.9	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.6	16.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.6	35.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	8.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5	23.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.5	10.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.5	0.9	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.5	13.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.4	11.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4	7.0	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4	13.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	4.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.3	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	10.8	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	12.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.3	19.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	4.3	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.3	1.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3	5.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	5.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.3	7.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	2.8	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.3	2.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.2	0.7	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.2	4.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	6.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	4.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	8.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	7.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	1.5	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.2	2.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	3.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	3.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	2.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	3.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	5.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	3.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	1.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	4.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	2.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	2.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	4.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	3.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.5	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1	16.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	3.2	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	5.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	3.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	5.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.2	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	1.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	3.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	5.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	8.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	0.7	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.5	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	1.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	0.9	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	4.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	1.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	1.6	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.2	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	0.8	REACTOME OPSINS	Genes involved in Opsins
0.1	1.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	1.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.9	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.1	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.7	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	4.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	3.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.7	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	1.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.7	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	1.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	0.9	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.4	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	3.0	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.5	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	2.6	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.8	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.4	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.8	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	1.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	6.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.8	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.6	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	2.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	1.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	5.2	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.6	3.0	GO:1990425	ryanodine receptor complex(GO:1990425)
0.4	2.6	GO:0043196	varicosity(GO:0043196)
0.3	2.8	GO:0097208	alveolar lamellar body(GO:0097208)
0.3	2.4	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	1.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.3	0.9	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	4.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	1.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	0.6	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	1.5	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.6	GO:0014802	terminal cisterna(GO:0014802)
0.1	0.9	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.6	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.1	2.5	GO:0030057	desmosome(GO:0030057)
0.1	0.4	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.4	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.3	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	0.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.6	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	1.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.7	GO:0002116	semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443)
0.1	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.9	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	1.2	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.7	GO:0000815	ESCRT III complex(GO:0000815)
0.1	0.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.6	GO:0005642	annulate lamellae(GO:0005642)
0.1	1.5	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0031673	H zone(GO:0031673)
0.0	1.3	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.9	GO:0000242	pericentriolar material(GO:0000242)
0.0	1.5	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.2	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.0	0.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	1.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.3	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.8	GO:0005902	microvillus(GO:0005902)
0.0	0.8	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.8	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	6.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.5	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.5	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	2.1	GO:0005903	brush border(GO:0005903)
0.0	2.0	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.4	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.3	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	2.0	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	1.0	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	1.1	GO:0031410	cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0055087	Ski complex(GO:0055087)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.3	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	1.4	GO:0005923	bicellular tight junction(GO:0005923)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	12.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.1	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.1	1.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	1.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.5	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	1.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	2.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.9	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	2.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.5	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	1.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	1.3	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	3.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	2.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	1.9	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	5.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.8	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	2.8	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	1.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	2.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.7	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.2	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.8	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.9	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	2.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	3.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	0.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	1.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	1.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	4.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	4.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	5.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	4.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	1.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	2.2	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.9	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.8	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.3	PID EPHB FWD PATHWAY	EPHB forward signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.2	0.8	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.0	0.5	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	5.6	GO:0043209	myelin sheath(GO:0043209)
0.0	0.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.7	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.8	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.3	3.8	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.2	3.7	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.9	3.5	GO:0061289	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.8	3.3	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.7	2.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.7	5.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.7	3.4	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6	1.9	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.6	1.8	GO:0060621	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.6	3.6	GO:0030421	defecation(GO:0030421)
0.6	1.7	GO:0061010	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.5	2.1	GO:0014028	notochord formation(GO:0014028)
0.5	2.3	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.4	2.1	GO:1902896	terminal web assembly(GO:1902896)
0.4	1.5	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.4	1.4	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.3	1.4	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.3	2.0	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3	1.0	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.3	0.9	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.3	0.9	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.3	3.0	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.3	0.8	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3	1.0	GO:1903288	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.2	0.7	GO:0010652	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2	2.0	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.2	1.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	4.8	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.2	0.9	GO:0099542	retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2	0.5	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2	1.1	GO:0032571	response to vitamin K(GO:0032571)
0.2	0.6	GO:2000777	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2	2.3	GO:0035437	maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2	0.6	GO:1904479	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.2	2.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2	1.5	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2	0.3	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.2	0.5	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.2	1.5	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1	0.7	GO:0044855	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1	1.9	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	0.4	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	3.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.4	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1	0.7	GO:0003070	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1	0.4	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1	0.8	GO:0035803	egg coat formation(GO:0035803)
0.1	0.4	GO:1903570	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1	0.4	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	2.7	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1	0.7	GO:0046208	spermine catabolic process(GO:0046208)
0.1	0.6	GO:0048478	replication fork protection(GO:0048478)
0.1	0.5	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	2.5	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	1.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.8	GO:0001767	establishment of lymphocyte polarity(GO:0001767)
0.1	0.3	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.1	0.5	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1	0.1	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1	0.2	GO:0060300	regulation of cytokine activity(GO:0060300)
0.1	0.6	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1	0.2	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	1.1	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.3	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	1.8	GO:0006907	pinocytosis(GO:0006907)
0.1	1.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.8	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.1	0.6	GO:0051414	response to cortisol(GO:0051414)
0.1	0.2	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1	0.3	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	1.3	GO:0016264	gap junction assembly(GO:0016264)
0.1	2.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.2	GO:0061386	closure of optic fissure(GO:0061386)
0.1	0.8	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1	3.7	GO:0021545	cranial nerve development(GO:0021545)
0.1	0.8	GO:2000194	regulation of female gonad development(GO:2000194)
0.1	0.3	GO:0051582	peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.6	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.4	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.2	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.1	2.0	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.9	GO:0002021	response to dietary excess(GO:0002021)
0.0	1.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.2	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.3	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.0	0.7	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.5	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.7	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0	0.2	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.1	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0	0.1	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0	0.4	GO:0002911	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.3	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	1.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0	1.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	2.1	GO:0007566	embryo implantation(GO:0007566)
0.0	2.6	GO:0007602	phototransduction(GO:0007602)
0.0	0.5	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	1.3	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	1.4	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.9	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.2	GO:0090131	mesenchyme migration(GO:0090131)
0.0	0.2	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.4	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0	0.2	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0	0.6	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0060969	negative regulation of gene silencing(GO:0060969)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:0060579	ventral spinal cord interneuron specification(GO:0021521) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.1	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0	0.4	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.1	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.1	GO:0039003	pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) metanephric nephron tubule formation(GO:0072289) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0	0.8	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.4	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.5	GO:0032967	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0	0.2	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.0	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.1	GO:1903433	regulation of constitutive secretory pathway(GO:1903433)
0.0	0.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.9	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	1.0	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.4	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.0	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0	0.1	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.1	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0043383	negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0	0.1	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3	1.3	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3	1.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	2.2	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2	1.0	GO:0097527	Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.1	1.8	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.9	GO:0035803	egg coat formation(GO:0035803)
0.1	0.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1	0.9	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1	0.3	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	0.5	GO:0051414	response to cortisol(GO:0051414)
0.1	0.7	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.1	1.8	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0	0.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.0	0.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
0.0	0.1	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.2	GO:0009441	glycolate metabolic process(GO:0009441)
0.0	0.2	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0	0.1	GO:1905068	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0	0.1	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.7	GO:0010107	potassium ion import(GO:0010107)
0.0	0.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.3	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	2.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	5.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	2.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	2.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	1.5	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.3	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
2.5	22.9	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
2.5	10.1	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
2.3	9.3	GO:1902613	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
1.8	5.3	GO:0019858	cytosine metabolic process(GO:0019858)
1.6	3.2	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
1.5	10.4	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
1.5	4.4	GO:0032773	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
1.5	8.8	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.4	4.1	GO:0003064	regulation of heart rate by hormone(GO:0003064)
1.4	1.4	GO:1905232	cellular response to L-glutamate(GO:1905232)
1.4	5.4	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.3	1.3	GO:1904036	negative regulation of epithelial cell apoptotic process(GO:1904036)
1.1	4.6	GO:0033484	nitric oxide homeostasis(GO:0033484)
1.1	5.6	GO:0002159	desmosome assembly(GO:0002159)
1.1	7.7	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
1.1	4.4	GO:1900535	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
1.0	4.9	GO:1902904	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.9	2.8	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.9	2.7	GO:0060166	olfactory pit development(GO:0060166)
0.9	2.6	GO:0046066	dGDP metabolic process(GO:0046066)
0.9	1.7	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
0.8	24.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.8	4.1	GO:0035617	stress granule disassembly(GO:0035617)
0.8	0.8	GO:0060018	astrocyte fate commitment(GO:0060018)
0.8	4.0	GO:2001074	regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.8	4.8	GO:0022614	membrane to membrane docking(GO:0022614)
0.8	2.4	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.8	2.4	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.8	4.0	GO:0035900	response to isolation stress(GO:0035900)
0.8	0.8	GO:0072023	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.8	2.3	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.8	2.3	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.7	2.2	GO:0006550	isoleucine catabolic process(GO:0006550)
0.7	5.9	GO:0044351	macropinocytosis(GO:0044351)
0.7	1.4	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
0.7	3.6	GO:1990834	response to odorant(GO:1990834)
0.7	2.1	GO:0048627	myoblast development(GO:0048627)
0.7	2.1	GO:0042938	dipeptide transport(GO:0042938)
0.7	2.1	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.7	5.7	GO:0031642	negative regulation of myelination(GO:0031642)
0.7	9.2	GO:0015671	oxygen transport(GO:0015671)
0.7	2.1	GO:2001162	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.7	2.8	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.7	7.7	GO:0060056	mammary gland involution(GO:0060056)
0.7	2.1	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.7	3.4	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.7	2.7	GO:1903781	positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.7	2.0	GO:0014740	negative regulation of muscle hyperplasia(GO:0014740)
0.7	1.3	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.7	0.7	GO:0045921	positive regulation of exocytosis(GO:0045921)
0.6	3.8	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.6	1.3	GO:0031133	regulation of axon diameter(GO:0031133)
0.6	0.6	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.6	0.6	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.6	1.8	GO:0002317	plasma cell differentiation(GO:0002317)
0.6	2.4	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.6	3.6	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.6	1.8	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.6	2.3	GO:1905073	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.6	4.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.6	1.7	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.6	1.7	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.6	1.7	GO:0006597	spermine biosynthetic process(GO:0006597)
0.6	2.8	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.6	1.7	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.6	3.4	GO:0006177	GMP biosynthetic process(GO:0006177)
0.6	1.7	GO:0001928	regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.6	0.6	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.6	5.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6	0.6	GO:1902307	positive regulation of sodium ion transmembrane transport(GO:1902307)
0.6	0.6	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.5	6.0	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.5	1.6	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.5	2.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.5	1.6	GO:0042418	epinephrine biosynthetic process(GO:0042418)
0.5	2.6	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.5	0.5	GO:0009106	lipoate metabolic process(GO:0009106)
0.5	1.6	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.5	3.6	GO:0000710	meiotic mismatch repair(GO:0000710)
0.5	0.5	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.5	2.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5	3.1	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.5	1.5	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.5	1.5	GO:1904897	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.5	5.0	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.5	0.5	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.5	7.9	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.5	1.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.5	1.0	GO:0070933	histone H4 deacetylation(GO:0070933)
0.5	1.5	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.5	1.5	GO:0046102	inosine metabolic process(GO:0046102)
0.5	2.9	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.5	1.0	GO:0097212	lysosomal membrane organization(GO:0097212)
0.5	3.4	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.5	6.3	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.5	1.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.5	2.3	GO:0015862	uridine transport(GO:0015862)
0.5	4.7	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5	4.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.5	1.8	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.5	1.4	GO:0009258	10-formyltetrahydrofolate catabolic process(GO:0009258)
0.5	1.4	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.5	1.8	GO:0090579	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.5	1.8	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.4	0.9	GO:0051054	positive regulation of DNA metabolic process(GO:0051054)
0.4	0.9	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.4	2.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.4	3.6	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.4	2.7	GO:0035709	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.4	0.4	GO:1903423	positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.4	1.3	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4	1.3	GO:0044209	AMP salvage(GO:0044209)
0.4	6.6	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4	2.2	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4	3.5	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.4	2.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.4	2.6	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.4	1.3	GO:0009447	putrescine catabolic process(GO:0009447)
0.4	3.0	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4	4.7	GO:0090168	Golgi reassembly(GO:0090168)
0.4	1.7	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.4	1.7	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.4	1.3	GO:0035350	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.4	3.8	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.4	2.5	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.4	2.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4	1.3	GO:0046081	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.4	2.1	GO:0035063	nuclear speck organization(GO:0035063)
0.4	1.2	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4	1.6	GO:0019322	pentose biosynthetic process(GO:0019322)
0.4	1.2	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.4	1.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.4	0.8	GO:2000374	regulation of oxygen metabolic process(GO:2000374)
0.4	2.8	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4	1.6	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.4	1.6	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.4	0.8	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.4	0.4	GO:2000591	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.4	0.4	GO:0031627	telomeric loop formation(GO:0031627)
0.4	0.4	GO:0035904	aorta development(GO:0035904)
0.4	3.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.4	1.2	GO:0007113	endomitotic cell cycle(GO:0007113)
0.4	3.2	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.4	0.8	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4	1.2	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.4	2.7	GO:1900086	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.4	1.2	GO:0031938	regulation of chromatin silencing at telomere(GO:0031938)
0.4	0.4	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.4	1.5	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.4	1.2	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4	1.5	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.4	1.9	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.4	1.5	GO:0042247	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.4	1.1	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.4	2.6	GO:0030043	actin filament fragmentation(GO:0030043)
0.4	0.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.4	0.4	GO:0060455	negative regulation of gastric acid secretion(GO:0060455)
0.4	2.6	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.4	0.4	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.4	1.8	GO:0051622	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.4	1.1	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.4	1.5	GO:0042335	cuticle development(GO:0042335)
0.4	2.9	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.4	0.4	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
0.4	0.7	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.4	2.2	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.4	0.4	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.4	1.8	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4	1.1	GO:1902534	single-organism membrane invagination(GO:1902534)
0.4	1.8	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4	0.4	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.3	0.3	GO:0060613	fat pad development(GO:0060613)
0.3	3.8	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.3	2.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.3	0.7	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3	1.7	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3	0.3	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.3	1.0	GO:0002188	translation reinitiation(GO:0002188)
0.3	3.4	GO:0010265	SCF complex assembly(GO:0010265)
0.3	0.3	GO:0071035	nuclear ncRNA surveillance(GO:0071029) CUT catabolic process(GO:0071034) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) CUT metabolic process(GO:0071043) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.3	1.3	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.3	1.0	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3	0.7	GO:0032486	Rap protein signal transduction(GO:0032486)
0.3	0.3	GO:0072221	distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.3	1.0	GO:0008355	olfactory learning(GO:0008355)
0.3	0.7	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3	0.3	GO:0021764	amygdala development(GO:0021764)
0.3	0.3	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.3	3.3	GO:0032808	lacrimal gland development(GO:0032808)
0.3	1.6	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.3	1.3	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3	2.3	GO:0051414	response to cortisol(GO:0051414)
0.3	1.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.3	1.3	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.3	2.6	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3	1.9	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.3	0.3	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.3	1.0	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3	0.3	GO:0043634	polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.3	1.6	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.3	2.2	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.3	1.9	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.3	2.8	GO:0034214	protein hexamerization(GO:0034214)
0.3	0.6	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3	1.6	GO:0098502	DNA dephosphorylation(GO:0098502)
0.3	0.9	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.3	2.5	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3	6.0	GO:0032060	bleb assembly(GO:0032060)
0.3	0.6	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.3	0.6	GO:2000196	positive regulation of female gonad development(GO:2000196)
0.3	2.8	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.3	0.9	GO:2000173	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.3	0.9	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.3	0.6	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.3	0.3	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.3	1.2	GO:0001806	type IV hypersensitivity(GO:0001806)
0.3	1.2	GO:0003409	optic cup structural organization(GO:0003409)
0.3	3.0	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.3	2.4	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.3	2.4	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.3	0.9	GO:0060152	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.3	0.9	GO:1901656	glycoside transport(GO:1901656)
0.3	1.2	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3	2.1	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.3	2.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.3	0.6	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.3	0.9	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3	1.5	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.3	0.6	GO:0033127	regulation of histone phosphorylation(GO:0033127)
0.3	4.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.3	0.9	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.3	3.9	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3	2.4	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.3	0.3	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.3	1.8	GO:0015820	leucine transport(GO:0015820)
0.3	1.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3	0.6	GO:0035733	hepatic stellate cell activation(GO:0035733)
0.3	3.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.3	3.2	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.3	15.6	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.3	0.3	GO:0070527	platelet aggregation(GO:0070527)
0.3	0.6	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.3	3.5	GO:0070986	left/right axis specification(GO:0070986)
0.3	3.8	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.3	0.9	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.3	0.9	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.3	1.7	GO:0051661	maintenance of centrosome location(GO:0051661)
0.3	1.2	GO:0031077	post-embryonic camera-type eye development(GO:0031077)
0.3	0.6	GO:0002582	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3	0.9	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3	0.6	GO:0070487	monocyte aggregation(GO:0070487)
0.3	0.9	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
0.3	0.9	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3	0.3	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990)
0.3	2.3	GO:0015705	iodide transport(GO:0015705)
0.3	0.3	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.3	0.3	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3	1.1	GO:0006226	dUMP biosynthetic process(GO:0006226)
0.3	2.0	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3	0.3	GO:0015801	aromatic amino acid transport(GO:0015801)
0.3	2.5	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3	2.5	GO:0048853	forebrain morphogenesis(GO:0048853)
0.3	0.3	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.3	0.8	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3	1.4	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.3	0.6	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.3	4.5	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.3	1.4	GO:1904579	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.3	1.9	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.3	2.8	GO:0038203	TORC2 signaling(GO:0038203)
0.3	2.2	GO:0034465	response to carbon monoxide(GO:0034465)
0.3	1.1	GO:0072719	cellular response to cisplatin(GO:0072719)
0.3	3.9	GO:0006089	lactate metabolic process(GO:0006089)
0.3	0.8	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
0.3	0.5	GO:0097435	fibril organization(GO:0097435)
0.3	1.6	GO:0006741	NADP biosynthetic process(GO:0006741)
0.3	0.3	GO:0001927	exocyst assembly(GO:0001927)
0.3	0.8	GO:0019417	sulfur oxidation(GO:0019417)
0.3	0.3	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3	5.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.3	0.8	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.3	0.8	GO:0060323	head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.3	3.2	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.3	0.3	GO:0061000	negative regulation of dendritic spine development(GO:0061000) negative regulation of dendritic spine morphogenesis(GO:0061002)
0.3	0.5	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3	2.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.3	0.3	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.3	0.5	GO:0036337	Fas signaling pathway(GO:0036337)
0.3	1.1	GO:0051013	microtubule severing(GO:0051013)
0.3	1.6	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.3	0.5	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.3	0.8	GO:0045073	regulation of chemokine biosynthetic process(GO:0045073) positive regulation of chemokine biosynthetic process(GO:0045080)
0.3	2.9	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.3	0.3	GO:0072053	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.3	0.8	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.3	0.5	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.3	2.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.3	0.3	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.3	0.3	GO:1990910	response to hypobaric hypoxia(GO:1990910)
0.3	1.3	GO:0090649	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3	0.3	GO:0009397	folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.3	0.8	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.3	0.3	GO:0021539	subthalamus development(GO:0021539)
0.3	2.3	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.3	4.1	GO:0043248	proteasome assembly(GO:0043248)
0.3	2.3	GO:0060717	chorion development(GO:0060717)
0.3	0.8	GO:1904528	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.3	1.3	GO:0060992	response to fungicide(GO:0060992)
0.3	1.0	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.3	2.8	GO:0035095	behavioral response to nicotine(GO:0035095)
0.3	0.8	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.3	9.3	GO:0032456	endocytic recycling(GO:0032456)
0.3	0.3	GO:0030321	transepithelial chloride transport(GO:0030321)
0.3	1.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.2	1.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	1.0	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.2	1.5	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.2	0.2	GO:1990502	dense core granule maturation(GO:1990502)
0.2	0.2	GO:1904868	establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2	1.7	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2	1.2	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.2	0.2	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.2	1.2	GO:0060022	hard palate development(GO:0060022)
0.2	1.2	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2	0.2	GO:0071283	cellular response to iron(III) ion(GO:0071283)
0.2	0.5	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.2	1.4	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.2	0.5	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.2	1.2	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2	0.2	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560)
0.2	0.2	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.2	1.7	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.2	0.7	GO:0042700	luteinizing hormone signaling pathway(GO:0042700)
0.2	0.9	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.2	0.7	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.2	0.2	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2	0.2	GO:0002339	response to molecule of fungal origin(GO:0002238) B cell selection(GO:0002339) cellular response to molecule of fungal origin(GO:0071226)
0.2	0.9	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2	0.5	GO:0050819	negative regulation of coagulation(GO:0050819)
0.2	0.2	GO:0035087	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.2	0.7	GO:0044848	biological phase(GO:0044848)
0.2	0.2	GO:0003139	secondary heart field specification(GO:0003139)
0.2	0.9	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.2	0.5	GO:0051014	actin filament severing(GO:0051014)
0.2	1.6	GO:0042692	muscle cell differentiation(GO:0042692)
0.2	0.7	GO:0061450	trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
0.2	1.4	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.2	0.5	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2	0.7	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
0.2	0.5	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2	0.5	GO:0010842	retina layer formation(GO:0010842)
0.2	1.1	GO:0051601	exocyst localization(GO:0051601)
0.2	0.7	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.2	0.4	GO:0009386	translational attenuation(GO:0009386)
0.2	0.2	GO:0003404	optic vesicle morphogenesis(GO:0003404)
0.2	0.7	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2	2.9	GO:0007220	Notch receptor processing(GO:0007220)
0.2	0.7	GO:0048687	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2	0.4	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.2	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.2	0.4	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2	1.1	GO:0002084	protein depalmitoylation(GO:0002084)
0.2	0.7	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.2	0.2	GO:0016078	tRNA catabolic process(GO:0016078)
0.2	0.4	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.2	1.3	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.2	0.7	GO:0050894	determination of affect(GO:0050894)
0.2	0.9	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2	1.3	GO:0006196	AMP catabolic process(GO:0006196)
0.2	0.4	GO:0015866	ADP transport(GO:0015866)
0.2	1.3	GO:0015853	adenine transport(GO:0015853)
0.2	0.6	GO:0051300	spindle pole body duplication(GO:0030474) nuclear pore distribution(GO:0031081) spindle pole body organization(GO:0051300) nuclear pore localization(GO:0051664) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2	0.9	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.2	5.6	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.2	1.3	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.2	0.9	GO:0042256	mature ribosome assembly(GO:0042256)
0.2	0.8	GO:2001169	regulation of ATP biosynthetic process(GO:2001169)
0.2	0.2	GO:0031365	N-terminal protein amino acid modification(GO:0031365)
0.2	1.3	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	3.8	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2	0.6	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2	0.4	GO:0043697	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2	0.4	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.2	7.8	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2	0.4	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.2	0.8	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.2	0.4	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.2	3.3	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.2	0.8	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.2	1.2	GO:0051643	endoplasmic reticulum localization(GO:0051643)
0.2	0.2	GO:0036065	fucosylation(GO:0036065)
0.2	4.4	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.2	0.8	GO:0046952	ketone body catabolic process(GO:0046952)
0.2	0.2	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.2	0.2	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.2	2.9	GO:0006105	succinate metabolic process(GO:0006105)
0.2	0.8	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2	0.6	GO:0097264	self proteolysis(GO:0097264)
0.2	1.0	GO:0030047	actin modification(GO:0030047)
0.2	0.2	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.2	1.4	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2	1.4	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2	2.0	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.2	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.2	1.0	GO:0032096	negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.2	0.8	GO:0006542	glutamine biosynthetic process(GO:0006542)
0.2	0.4	GO:0006997	nucleus organization(GO:0006997)
0.2	1.2	GO:0043542	endothelial cell migration(GO:0043542)
0.2	2.6	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.2	0.8	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.2	0.6	GO:0046060	dATP metabolic process(GO:0046060)
0.2	2.4	GO:0001778	plasma membrane repair(GO:0001778)
0.2	7.4	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2	1.2	GO:1903573	negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.2	1.0	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.2	2.2	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.2	0.6	GO:2000681	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2	0.4	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.2	0.8	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.2	0.8	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.2	0.6	GO:0035995	detection of muscle stretch(GO:0035995)
0.2	0.2	GO:0036090	cleavage furrow ingression(GO:0036090)
0.2	0.4	GO:0006738	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.2	2.0	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.2	1.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2	1.8	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2	2.5	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.2	1.4	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2	0.8	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2	4.9	GO:0006337	nucleosome disassembly(GO:0006337)
0.2	1.4	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.2	2.9	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2	1.9	GO:0030322	stabilization of membrane potential(GO:0030322)
0.2	0.6	GO:0070193	synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.2	1.9	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2	1.7	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.2	1.0	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.2	1.5	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.2	6.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.2	1.0	GO:0070987	error-free translesion synthesis(GO:0070987)
0.2	1.0	GO:0060847	blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101)
0.2	1.9	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.2	0.8	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.2	0.9	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.2	2.8	GO:0000338	protein deneddylation(GO:0000338)
0.2	1.5	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.2	0.6	GO:0016071	mRNA metabolic process(GO:0016071)
0.2	1.3	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.2	0.6	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.2	0.6	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2	0.2	GO:2000366	regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.2	0.2	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.2	1.1	GO:0009597	detection of virus(GO:0009597)
0.2	0.4	GO:0060017	parathyroid gland development(GO:0060017)
0.2	0.4	GO:0070781	response to biotin(GO:0070781)
0.2	3.3	GO:0016540	protein autoprocessing(GO:0016540)
0.2	0.9	GO:0032119	sequestering of zinc ion(GO:0032119)
0.2	5.7	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.2	0.6	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.2	1.5	GO:0006600	creatine metabolic process(GO:0006600)
0.2	2.6	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.2	0.4	GO:0003350	pulmonary myocardium development(GO:0003350)
0.2	0.2	GO:0002839	positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839)
0.2	0.4	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2	1.1	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.2	1.8	GO:0009249	protein lipoylation(GO:0009249)
0.2	1.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2	1.1	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2	0.4	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.2	0.5	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2	0.7	GO:2000618	regulation of histone H4-K16 acetylation(GO:2000618)
0.2	0.4	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.2	1.1	GO:0070383	DNA cytosine deamination(GO:0070383)
0.2	0.2	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2	0.4	GO:0045807	positive regulation of endocytosis(GO:0045807)
0.2	0.7	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.2	2.7	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.2	0.2	GO:1990089	response to nerve growth factor(GO:1990089)
0.2	5.1	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.2	0.9	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.2	0.4	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.2	2.6	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2	0.2	GO:0000154	rRNA modification(GO:0000154)
0.2	0.5	GO:0042823	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.2	0.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	3.0	GO:0006999	nuclear pore organization(GO:0006999)
0.2	0.5	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.2	0.5	GO:0070142	synaptic vesicle budding(GO:0070142)
0.2	9.0	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2	0.9	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.2	0.9	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.2	0.9	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.2	1.0	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.2	1.7	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.2	0.7	GO:0006366	transcription from RNA polymerase II promoter(GO:0006366)
0.2	0.5	GO:0006404	RNA import into nucleus(GO:0006404)
0.2	1.0	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.2	0.3	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.2	0.7	GO:0000729	DNA double-strand break processing(GO:0000729)
0.2	0.8	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2	0.2	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.2	0.5	GO:0043587	tongue morphogenesis(GO:0043587)
0.2	1.2	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.2	1.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.2	0.5	GO:1990764	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2	2.8	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.2	0.2	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.2	0.5	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.2	0.2	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.2	1.0	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.2	0.8	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.2	1.1	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.2	0.2	GO:0048754	branching morphogenesis of an epithelial tube(GO:0048754)
0.2	0.5	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.2	0.2	GO:0035803	egg coat formation(GO:0035803)
0.2	0.2	GO:0060061	Spemann organizer formation(GO:0060061)
0.2	1.6	GO:0000076	DNA replication checkpoint(GO:0000076)
0.2	0.6	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.2	0.8	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.2	0.6	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.2	0.5	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.2	0.5	GO:0014807	regulation of somitogenesis(GO:0014807)
0.2	0.3	GO:0033135	regulation of peptidyl-serine phosphorylation(GO:0033135)
0.2	0.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.2	0.3	GO:1905166	negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.2	0.3	GO:0031507	heterochromatin assembly(GO:0031507)
0.2	0.2	GO:0006816	calcium ion transport(GO:0006816)
0.2	0.2	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451)
0.2	0.2	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.2	1.2	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.2	0.8	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.2	0.5	GO:0001880	Mullerian duct regression(GO:0001880)
0.2	0.3	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.2	0.5	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2	0.3	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.2	4.0	GO:0043968	histone H2A acetylation(GO:0043968)
0.2	13.0	GO:0006415	translational termination(GO:0006415)
0.2	0.2	GO:0070918	dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.2	0.8	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.2	0.6	GO:0001842	neural fold formation(GO:0001842)
0.2	0.3	GO:2000109	regulation of macrophage apoptotic process(GO:2000109)
0.1	1.0	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	1.9	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	2.4	GO:0031268	pseudopodium organization(GO:0031268)
0.1	1.0	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.4	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1	1.0	GO:0046618	drug export(GO:0046618)
0.1	0.6	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.4	GO:0061218	negative regulation of mesonephros development(GO:0061218) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1	0.3	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.1	GO:0009060	aerobic respiration(GO:0009060)
0.1	0.4	GO:0010912	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.1	0.1	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.1	4.6	GO:0071378	cellular response to growth hormone stimulus(GO:0071378)
0.1	0.4	GO:0061198	fungiform papilla formation(GO:0061198)
0.1	0.4	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.1	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1	0.7	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	1.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.1	1.5	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.4	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.4	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.1	0.7	GO:0052428	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) modification by host of symbiont molecular function(GO:0052428)
0.1	1.6	GO:0030913	paranodal junction assembly(GO:0030913)
0.1	0.1	GO:0002934	desmosome organization(GO:0002934)
0.1	0.4	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.1	0.4	GO:1904529	regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.1	0.6	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.1	0.4	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.4	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
0.1	1.0	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.3	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.1	0.1	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
0.1	13.0	GO:0070268	cornification(GO:0070268)
0.1	2.3	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	1.6	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.4	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1	0.6	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.3	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	1.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	0.8	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
0.1	0.3	GO:0072553	terminal button organization(GO:0072553)
0.1	0.6	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	1.1	GO:0015858	nucleoside transport(GO:0015858)
0.1	0.6	GO:0002880	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1	0.4	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.1	0.8	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.3	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.1	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0015872	dopamine transport(GO:0015872)
0.1	0.3	GO:0072205	metanephric collecting duct development(GO:0072205)
0.1	0.1	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.1	1.0	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.1	0.7	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.1	1.2	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.3	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.1	1.7	GO:0034349	glial cell apoptotic process(GO:0034349)
0.1	0.3	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1	0.3	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.3	GO:0071109	superior temporal gyrus development(GO:0071109)
0.1	0.7	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	3.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.1	1.0	GO:0043482	pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482)
0.1	1.2	GO:0060674	placenta blood vessel development(GO:0060674)
0.1	1.4	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.1	0.5	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.1	0.9	GO:0021511	spinal cord patterning(GO:0021511)
0.1	0.3	GO:1903722	regulation of centriole elongation(GO:1903722)
0.1	0.4	GO:0048511	rhythmic process(GO:0048511)
0.1	1.5	GO:0045686	negative regulation of glial cell differentiation(GO:0045686)
0.1	0.5	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1	0.1	GO:0044108	cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.1	0.5	GO:0021759	globus pallidus development(GO:0021759)
0.1	0.1	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.1	0.7	GO:0097338	response to clozapine(GO:0097338)
0.1	2.9	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.7	GO:0070269	pyroptosis(GO:0070269)
0.1	2.7	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.1	1.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.1	1.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.1	GO:0002644	negative regulation of tolerance induction(GO:0002644)
0.1	3.4	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
0.1	1.0	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.3	GO:0046958	nonassociative learning(GO:0046958)
0.1	0.9	GO:0033233	regulation of protein sumoylation(GO:0033233)
0.1	1.8	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.1	0.3	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.3	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1	1.4	GO:1901070	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) guanosine-containing compound biosynthetic process(GO:1901070)
0.1	0.3	GO:0045006	DNA deamination(GO:0045006)
0.1	1.3	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1	2.9	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1	0.3	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.1	0.5	GO:0071888	macrophage apoptotic process(GO:0071888)
0.1	0.8	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.1	1.9	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.8	GO:0006970	response to osmotic stress(GO:0006970)
0.1	0.4	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.9	GO:0021960	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) anterior commissure morphogenesis(GO:0021960) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1	0.1	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.1	0.4	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.1	0.5	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1	0.6	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	3.9	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1	6.4	GO:0015701	bicarbonate transport(GO:0015701)
0.1	0.5	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	0.4	GO:0071344	diphosphate metabolic process(GO:0071344)
0.1	0.4	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	0.5	GO:0030259	lipid glycosylation(GO:0030259)
0.1	0.4	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	0.1	GO:1900223	positive regulation of beta-amyloid clearance(GO:1900223)
0.1	0.1	GO:1904796	regulation of core promoter binding(GO:1904796)
0.1	0.7	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
0.1	0.8	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1	2.6	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.4	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.1	0.2	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1	0.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.1	1.4	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.1	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.1	0.4	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.1	0.2	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.1	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	1.3	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.1	1.1	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1	0.2	GO:0046351	disaccharide biosynthetic process(GO:0046351)
0.1	0.5	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.1	0.1	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.1	GO:1990791	regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866) dorsal root ganglion development(GO:1990791)
0.1	0.1	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.1	0.5	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	0.2	GO:0018210	peptidyl-threonine modification(GO:0018210)
0.1	0.2	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.1	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.1	0.1	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.1	0.8	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.1	0.2	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1	0.2	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1	2.1	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1	0.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	3.7	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.1	0.9	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	1.0	GO:0072319	vesicle uncoating(GO:0072319)
0.1	0.3	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.5	GO:0016240	autophagosome docking(GO:0016240)
0.1	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	4.2	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.1	0.8	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	1.6	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.2	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.1	0.2	GO:0030825	positive regulation of cGMP metabolic process(GO:0030825)
0.1	0.3	GO:0010332	response to gamma radiation(GO:0010332)
0.1	3.0	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	0.1	GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1	0.3	GO:0033341	regulation of collagen binding(GO:0033341)
0.1	0.1	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.1	0.1	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1	1.2	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	0.4	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.1	1.2	GO:0014029	neural crest formation(GO:0014029)
0.1	0.3	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1	0.3	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1	0.9	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.2	GO:1901563	response to camptothecin(GO:1901563)
0.1	0.4	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.1	0.8	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.1	1.2	GO:0002003	angiotensin maturation(GO:0002003)
0.1	0.2	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1	1.1	GO:0090161	Golgi ribbon formation(GO:0090161)
0.1	0.2	GO:1904861	excitatory synapse assembly(GO:1904861)
0.1	0.3	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.1	0.2	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	2.8	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1	0.6	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.9	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.1	0.3	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1	0.3	GO:0099542	trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1	0.6	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.1	0.2	GO:0060454	positive regulation of gastric acid secretion(GO:0060454)
0.1	0.4	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.8	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.6	GO:0045338	farnesyl diphosphate metabolic process(GO:0045338)
0.1	0.2	GO:0046110	xanthine metabolic process(GO:0046110)
0.1	3.5	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.7	GO:0015698	inorganic anion transport(GO:0015698)
0.1	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.2	GO:0043379	memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380)
0.1	0.4	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.1	0.2	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.1	3.5	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.1	0.8	GO:0008340	determination of adult lifespan(GO:0008340)
0.1	0.5	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.1	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.1	0.9	GO:1900120	regulation of receptor binding(GO:1900120)
0.1	0.4	GO:0098838	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1	0.5	GO:0035799	ureter maturation(GO:0035799)
0.1	0.5	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.1	1.9	GO:0046039	GTP metabolic process(GO:0046039)
0.1	1.6	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.1	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.1	0.1	GO:0034982	protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.1	0.4	GO:0007619	courtship behavior(GO:0007619)
0.1	0.1	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.1	0.2	GO:0051784	negative regulation of nuclear division(GO:0051784)
0.1	0.1	GO:0048733	sebaceous gland development(GO:0048733)
0.1	2.0	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	0.2	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.1	0.3	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.6	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.8	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.1	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.1	0.1	GO:0006338	chromatin remodeling(GO:0006338)
0.1	0.3	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	1.3	GO:0045116	protein neddylation(GO:0045116)
0.1	0.4	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	4.0	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.2	GO:0002215	defense response to nematode(GO:0002215)
0.1	0.7	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.1	0.7	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	0.3	GO:0016129	phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.1	0.2	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	0.4	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.1	0.9	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.5	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.1	0.4	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.7	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.2	GO:0003358	noradrenergic neuron development(GO:0003358)
0.1	0.1	GO:0014005	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1	0.6	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	4.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	0.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.5	GO:0048102	autophagic cell death(GO:0048102)
0.1	0.1	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.1	0.4	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.5	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1	5.0	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.2	GO:0031126	snoRNA 3'-end processing(GO:0031126)
0.1	0.4	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.8	GO:0045345	positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1	1.7	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1	0.9	GO:0006108	malate metabolic process(GO:0006108)
0.1	2.3	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.1	0.9	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	1.5	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.6	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.1	0.5	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	0.3	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1	0.1	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1	0.8	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.1	0.3	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1	0.4	GO:0034334	adherens junction maintenance(GO:0034334)
0.1	0.4	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	0.8	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.6	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1	0.3	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.1	0.2	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1	0.2	GO:0051138	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1	0.3	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	2.4	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	0.1	GO:2000047	cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1	0.5	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.3	GO:0051452	intracellular pH reduction(GO:0051452)
0.1	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.3	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1	1.0	GO:0042559	pteridine-containing compound biosynthetic process(GO:0042559)
0.1	1.0	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.8	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	0.3	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	0.1	GO:2000757	negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1	0.3	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.1	0.5	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.4	GO:0021603	cranial nerve formation(GO:0021603)
0.1	0.3	GO:1900453	negative regulation of long term synaptic depression(GO:1900453) regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) regulation of connective tissue replacement(GO:1905203) negative regulation of connective tissue replacement(GO:1905204)
0.1	0.3	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.1	0.4	GO:0032218	riboflavin transport(GO:0032218)
0.1	0.6	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.6	GO:0021984	adenohypophysis development(GO:0021984)
0.1	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.1	0.3	GO:0072507	divalent inorganic cation homeostasis(GO:0072507)
0.1	0.3	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	0.3	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1	0.2	GO:0003341	cilium movement(GO:0003341)
0.1	0.4	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.3	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.1	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	0.4	GO:0035404	histone-serine phosphorylation(GO:0035404)
0.1	0.2	GO:0021854	hypothalamus development(GO:0021854)
0.1	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.6	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1	0.7	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	0.2	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.1	0.1	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.1	0.2	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.1	0.4	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.1	0.3	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.2	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.2	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1	0.1	GO:2000410	regulation of thymocyte migration(GO:2000410)
0.1	0.3	GO:0090335	regulation of brown fat cell differentiation(GO:0090335)
0.1	0.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.9	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.1	0.2	GO:0031017	exocrine pancreas development(GO:0031017)
0.1	0.1	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.1	0.2	GO:0007144	female meiosis I(GO:0007144)
0.1	0.1	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1	0.3	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1	0.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.1	0.1	GO:0060594	frontal suture morphogenesis(GO:0060364) mammary gland specification(GO:0060594)
0.1	0.3	GO:0050891	renal water homeostasis(GO:0003091) multicellular organismal water homeostasis(GO:0050891)
0.1	0.2	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.1	0.1	GO:0042048	olfactory behavior(GO:0042048)
0.1	0.2	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.4	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.1	0.6	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.1	GO:0021767	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.1	0.3	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.2	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1	0.3	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	0.6	GO:0006611	protein export from nucleus(GO:0006611)
0.1	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.5	GO:0032472	Golgi calcium ion transport(GO:0032472)
0.1	0.2	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.2	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	0.1	GO:0060290	transdifferentiation(GO:0060290)
0.1	0.2	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1	0.9	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	1.5	GO:1902603	carnitine transmembrane transport(GO:1902603)
0.1	0.1	GO:0090344	negative regulation of cell aging(GO:0090344)
0.1	0.3	GO:0032392	DNA geometric change(GO:0032392)
0.1	0.1	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.1	0.1	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.1	2.6	GO:0042407	cristae formation(GO:0042407)
0.1	0.1	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.1	2.4	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.1	0.2	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.1	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.1	0.2	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	0.2	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.1	0.1	GO:0001554	luteolysis(GO:0001554)
0.1	0.2	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1	0.4	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.1	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.1	0.3	GO:0043489	RNA stabilization(GO:0043489)
0.1	0.3	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.3	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1	0.2	GO:2001225	regulation of chloride transport(GO:2001225)
0.1	0.1	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.1	0.4	GO:0060416	response to growth hormone(GO:0060416)
0.1	0.8	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1	1.5	GO:0031114	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1	0.7	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.1	0.1	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.1	0.1	GO:0046325	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.1	1.1	GO:0019054	modulation by virus of host process(GO:0019054)
0.1	2.2	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	0.3	GO:0042756	drinking behavior(GO:0042756)
0.1	0.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1	0.2	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	0.1	GO:1902617	response to fluoride(GO:1902617)
0.1	2.7	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1	0.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	4.4	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.1	0.3	GO:0000012	single strand break repair(GO:0000012)
0.1	0.5	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.3	GO:2000825	regulation of androgen receptor activity(GO:2000823) positive regulation of androgen receptor activity(GO:2000825)
0.1	0.1	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.1	0.3	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.1	0.5	GO:1904871	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1	0.1	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.1	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.3	GO:0080009	mRNA methylation(GO:0080009)
0.1	0.4	GO:0010155	regulation of proton transport(GO:0010155)
0.1	0.1	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell(GO:1904994)
0.1	0.4	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.1	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	0.2	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.1	0.5	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.5	GO:0043966	histone H3 acetylation(GO:0043966)
0.1	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.1	1.5	GO:0032508	DNA duplex unwinding(GO:0032508)
0.1	0.1	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1	0.2	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.1	0.1	GO:0050803	regulation of synapse structure or activity(GO:0050803)
0.1	0.1	GO:0036490	regulation of translational initiation by eIF2 alpha phosphorylation(GO:0010998) regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1	0.2	GO:0006875	cellular metal ion homeostasis(GO:0006875)
0.1	0.3	GO:0015870	acetylcholine transport(GO:0015870)
0.1	0.6	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	0.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.3	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.3	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	2.5	GO:0008033	tRNA processing(GO:0008033)
0.1	0.3	GO:1904779	regulation of protein localization to centrosome(GO:1904779)
0.1	1.2	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.1	0.3	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.1	0.2	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1	0.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	4.7	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	0.5	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.1	0.1	GO:0007569	cell aging(GO:0007569)
0.1	0.1	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.1	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.1	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.1	0.6	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.1	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	0.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.2	GO:0001878	response to yeast(GO:0001878)
0.1	0.2	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1	0.2	GO:2001300	lipoxin metabolic process(GO:2001300)
0.1	0.2	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.1	0.1	GO:1903333	negative regulation of protein folding(GO:1903333)
0.1	0.1	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1	0.1	GO:0006533	aspartate catabolic process(GO:0006533)
0.1	0.5	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.1	0.3	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.1	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581)
0.1	0.2	GO:0071353	response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.1	0.1	GO:0036215	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	0.1	GO:1901800	positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.2	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.1	0.7	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.1	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.1	0.2	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.1	0.1	GO:0048593	camera-type eye morphogenesis(GO:0048593)
0.1	0.4	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.1	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.1	2.8	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	0.3	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.5	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.1	0.1	GO:0014824	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	0.3	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	0.1	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.1	0.6	GO:0048333	mesodermal cell differentiation(GO:0048333)
0.1	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.9	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.3	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.1	0.3	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.1	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	0.3	GO:0015791	polyol transport(GO:0015791)
0.1	0.1	GO:1903147	negative regulation of mitophagy(GO:1903147)
0.1	0.1	GO:0070141	response to UV-A(GO:0070141)
0.1	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.1	0.2	GO:0090260	negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1	0.3	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.1	0.2	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.1	0.2	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.1	0.2	GO:0090656	t-circle formation(GO:0090656)
0.1	0.4	GO:2000727	positive regulation of cardiac muscle cell differentiation(GO:2000727)
0.1	0.4	GO:0009642	response to light intensity(GO:0009642)
0.1	0.4	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.4	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	0.3	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
0.1	0.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	0.2	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.1	0.2	GO:0006835	dicarboxylic acid transport(GO:0006835)
0.1	0.2	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.2	GO:0072075	metanephric mesenchyme development(GO:0072075)
0.1	0.2	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1	0.1	GO:0060437	lung growth(GO:0060437)
0.1	0.6	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1	0.1	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.1	0.5	GO:0016180	snRNA processing(GO:0016180)
0.1	0.1	GO:0070828	heterochromatin organization(GO:0070828)
0.1	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.1	0.5	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.1	0.1	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.1	0.3	GO:0007638	mechanosensory behavior(GO:0007638)
0.1	0.5	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.1	0.2	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.9	GO:0006270	DNA replication initiation(GO:0006270)
0.1	0.3	GO:0070475	rRNA base methylation(GO:0070475)
0.1	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.2	GO:0035810	positive regulation of urine volume(GO:0035810)
0.1	0.3	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.6	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.4	GO:0098787	mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.4	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.0	GO:0035634	response to stilbenoid(GO:0035634)
0.0	0.1	GO:0009953	dorsal/ventral pattern formation(GO:0009953)
0.0	0.0	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.5	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.2	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.2	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.0	0.5	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.3	GO:0002692	negative regulation of cellular extravasation(GO:0002692)
0.0	0.1	GO:0036269	swimming behavior(GO:0036269)
0.0	0.0	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.2	GO:1904685	positive regulation of metalloendopeptidase activity(GO:1904685)
0.0	0.7	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.1	GO:1904647	response to rotenone(GO:1904647)
0.0	0.1	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.0	0.2	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.7	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.0	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0006110	regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811)
0.0	0.8	GO:0006825	copper ion transport(GO:0006825)
0.0	0.2	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.7	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0075713	establishment of integrated proviral latency(GO:0075713)
0.0	0.5	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.0	0.2	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.0	0.0	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.1	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0	0.0	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0	2.9	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.6	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0	0.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.5	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.8	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.3	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.2	GO:1903826	arginine transmembrane transport(GO:1903826)
0.0	0.5	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.5	GO:0007098	centrosome cycle(GO:0007098)
0.0	0.0	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0032526	response to retinoic acid(GO:0032526)
0.0	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.1	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.2	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.9	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.1	GO:1904353	regulation of telomere capping(GO:1904353)
0.0	0.6	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.4	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.8	GO:0051031	tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.0	GO:0008354	germ cell migration(GO:0008354)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.3	GO:0001510	RNA methylation(GO:0001510)
0.0	0.0	GO:0032466	negative regulation of cytokinesis(GO:0032466)
0.0	0.0	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.3	GO:0070861	regulation of protein exit from endoplasmic reticulum(GO:0070861)
0.0	0.0	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.2	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.8	GO:0031109	microtubule polymerization or depolymerization(GO:0031109)
0.0	0.0	GO:1902074	response to salt(GO:1902074)
0.0	0.1	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.6	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.6	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.6	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:2000765	regulation of cytoplasmic translation(GO:2000765)
0.0	0.2	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0	0.4	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244)
0.0	0.2	GO:0033692	cellular polysaccharide biosynthetic process(GO:0033692)
0.0	0.5	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.0	GO:0071373	cellular response to luteinizing hormone stimulus(GO:0071373)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.0	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.4	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.4	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.1	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:0045927	positive regulation of growth(GO:0045927)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.1	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	0.0	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.5	GO:0035588	G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.0	GO:0045347	regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0046521	sphingoid catabolic process(GO:0046521)
0.0	0.1	GO:1904031	positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0045210	FasL biosynthetic process(GO:0045210)
0.0	0.2	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.0	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.0	0.0	GO:0060767	epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
0.0	0.2	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.2	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.0	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.0	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.0	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.3	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.1	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0	0.0	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.2	GO:2000322	regulation of glucocorticoid receptor signaling pathway(GO:2000322)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.7	GO:0010107	potassium ion import(GO:0010107)
0.0	0.6	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.0	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.0	GO:0000187	activation of MAPK activity(GO:0000187)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.2	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.1	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.3	GO:0032402	melanosome transport(GO:0032402)
0.0	0.5	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0	0.0	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.0	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.0	0.1	GO:0002861	regulation of inflammatory response to antigenic stimulus(GO:0002861)
0.0	0.1	GO:0060482	lobar bronchus development(GO:0060482)
0.0	1.5	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.3	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.3	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:1904742	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
0.0	0.2	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.1	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.3	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
0.0	0.1	GO:0016045	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0	0.1	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
0.0	0.2	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.0	0.6	GO:0090382	phagosome maturation(GO:0090382)
0.0	0.1	GO:0044117	growth of symbiont in host(GO:0044117)
0.0	0.0	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0	1.3	GO:0006968	cellular defense response(GO:0006968)
0.0	0.2	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.0	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.2	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
0.0	0.1	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.1	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.0	0.1	GO:0033278	cell proliferation in midbrain(GO:0033278)
0.0	0.3	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0002580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.2	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.2	GO:0045187	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.2	GO:0038202	TORC1 signaling(GO:0038202)
0.0	0.1	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.0	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.4	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.2	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.1	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.4	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:1904814	regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.0	GO:0055119	relaxation of cardiac muscle(GO:0055119)
0.0	0.7	GO:0022900	electron transport chain(GO:0022900)
0.0	0.0	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.0	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.2	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.0	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0	0.0	GO:0045823	positive regulation of heart contraction(GO:0045823)
0.0	0.1	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.0	0.0	GO:0035561	regulation of chromatin binding(GO:0035561)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.0	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.2	GO:1900225	regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.0	0.1	GO:0048749	compound eye development(GO:0048749)
0.0	0.1	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.0	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.0	0.1	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.0	GO:0061314	Notch signaling involved in heart development(GO:0061314)
0.0	0.2	GO:0042761	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	4.6	GO:0000086	G2/M transition of mitotic cell cycle(GO:0000086)
0.0	0.0	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.4	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.6	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.0	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.0	GO:0022615	protein to membrane docking(GO:0022615)
0.0	0.3	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.2	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.1	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.5	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
0.0	0.0	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.0	0.1	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	1.0	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
0.0	0.1	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.1	GO:0003322	pancreatic A cell development(GO:0003322)
0.0	0.0	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.2	GO:0044030	regulation of DNA methylation(GO:0044030)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.2	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.1	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.4	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.5	GO:0070507	regulation of microtubule cytoskeleton organization(GO:0070507)
0.0	0.0	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0051057	positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0	0.4	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.1	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.1	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.0	0.2	GO:0006625	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0	1.0	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.2	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0050821	protein stabilization(GO:0050821)
0.0	0.1	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.0	0.0	GO:2001023	regulation of response to drug(GO:2001023)
0.0	0.5	GO:0032465	regulation of cytokinesis(GO:0032465)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.1	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.0	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0042351	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0	0.2	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.1	GO:0052565	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0	0.1	GO:0030451	regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.0	0.1	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.0	0.1	GO:0002001	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0	0.0	GO:0032414	positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0	0.0	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.0	0.2	GO:0001909	leukocyte mediated cytotoxicity(GO:0001909)
0.0	0.2	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.0	GO:0031023	microtubule organizing center organization(GO:0031023)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0061760	antifungal innate immune response(GO:0061760)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.1	GO:0006836	neurotransmitter transport(GO:0006836)
0.0	0.0	GO:0072641	type I interferon secretion(GO:0072641)
0.0	0.1	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.2	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:1905225	response to thyrotropin-releasing hormone(GO:1905225)
0.0	0.0	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.0	GO:0008272	sulfate transport(GO:0008272)
0.0	0.2	GO:0045727	positive regulation of translation(GO:0045727)
0.0	0.0	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.0	0.0	GO:0070231	T cell apoptotic process(GO:0070231)
0.0	0.1	GO:0086091	regulation of heart rate by cardiac conduction(GO:0086091)
0.0	0.0	GO:0060631	regulation of reciprocal meiotic recombination(GO:0010520) regulation of meiosis I(GO:0060631)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.0	0.1	GO:0032418	lysosome localization(GO:0032418)
0.0	0.4	GO:0035036	sperm-egg recognition(GO:0035036)
0.0	0.3	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.1	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	0.2	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.0	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.0	GO:1902713	regulation of interferon-gamma secretion(GO:1902713)
0.0	0.2	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.0	GO:0023058	adaptation of signaling pathway(GO:0023058)
0.0	0.1	GO:1900116	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.3	GO:1901998	toxin transport(GO:1901998)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.0	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.0	0.0	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	0.0	GO:1902573	positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0	0.3	GO:0061053	somite development(GO:0061053)
0.0	0.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.2	GO:0034776	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0	0.0	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.2	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.1	GO:0001504	neurotransmitter uptake(GO:0001504)
0.0	0.0	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0006568	tryptophan metabolic process(GO:0006568)
0.0	0.4	GO:0008306	associative learning(GO:0008306)
0.0	0.0	GO:0042755	eating behavior(GO:0042755)
0.0	0.0	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0	0.0	GO:0071897	DNA biosynthetic process(GO:0071897)
0.0	0.0	GO:0032400	melanosome localization(GO:0032400)
0.0	0.0	GO:0051966	regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0	0.0	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
0.0	0.0	GO:0007320	insemination(GO:0007320)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.0	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.0	0.0	GO:0043406	positive regulation of MAP kinase activity(GO:0043406)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	1.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.6	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	14.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.3	29.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	3.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	2.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	3.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	1.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	1.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	1.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	0.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	2.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.9	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	1.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	1.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	1.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.7	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	2.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.1	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	1.2	REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.2	8.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	2.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.9	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	3.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	2.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	1.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.2	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.1	0.7	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	0.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	3.8	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.0	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	1.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	1.1	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	4.7	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	2.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.6	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.8	4.5	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4	2.0	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2	1.2	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.2	1.6	GO:0016015	morphogen activity(GO:0016015)
0.2	1.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2	1.4	GO:0046923	ER retention sequence binding(GO:0046923)
0.2	1.2	GO:0036122	BMP binding(GO:0036122)
0.1	0.6	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.1	0.7	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1	1.0	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1	0.5	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.7	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	1.3	GO:0051434	BH3 domain binding(GO:0051434)
0.1	1.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.9	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.6	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	1.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	1.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.3	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	4.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	1.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.8	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.8	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.8	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.8	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.1	GO:0098770	FBXO family protein binding(GO:0098770)
0.0	0.5	GO:0017166	vinculin binding(GO:0017166)
0.0	0.4	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.2	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	1.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.9	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	1.2	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.2	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.4	GO:0030276	clathrin binding(GO:0030276)
0.0	0.3	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.2	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0	0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.8	GO:0043394	proteoglycan binding(GO:0043394)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.0	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.8	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.9	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	1.5	GO:0000149	SNARE binding(GO:0000149)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	8.7	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.3	0.9	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.3	1.7	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.2	1.0	GO:0031905	early endosome lumen(GO:0031905)
0.2	0.6	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.2	0.8	GO:0044530	supraspliceosomal complex(GO:0044530)
0.2	0.6	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.7	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.1	0.9	GO:0001939	female pronucleus(GO:0001939)
0.1	0.8	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.9	GO:0031010	ISWI-type complex(GO:0031010)
0.1	1.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.2	GO:0044094	host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1	0.6	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	0.5	GO:0005638	lamin filament(GO:0005638)
0.0	0.7	GO:0001741	XY body(GO:0001741)
0.0	0.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.5	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0	0.8	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	7.2	GO:0072562	blood microparticle(GO:0072562)
0.0	1.5	GO:0016235	aggresome(GO:0016235)
0.0	1.0	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.2	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	1.0	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.5	GO:0031105	septin complex(GO:0031105)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0045120	pronucleus(GO:0045120)
0.0	0.2	GO:1990909	catenin complex(GO:0016342) Wnt signalosome(GO:1990909)
0.0	0.6	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0035976	AP1 complex(GO:0035976)
0.0	0.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	2.9	GO:0005875	microtubule associated complex(GO:0005875)
0.0	1.6	GO:0005882	intermediate filament(GO:0005882)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.3	GO:0071565	nBAF complex(GO:0071565)
0.0	0.4	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.4	GO:0097542	ciliary tip(GO:0097542)
0.0	0.1	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.3	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	1.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	3.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	9.6	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
1.8	14.3	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.9	2.7	GO:0035501	MH1 domain binding(GO:0035501)
0.7	2.1	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.6	13.6	GO:0015929	hexosaminidase activity(GO:0015929)
0.6	2.6	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.6	2.6	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.5	1.6	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.5	8.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.5	4.5	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.5	2.8	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5	1.4	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.5	1.4	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.4	4.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.4	1.8	GO:0032145	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.4	4.8	GO:0051434	BH3 domain binding(GO:0051434)
0.4	1.7	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.4	1.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4	1.6	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.4	1.1	GO:0035500	MH2 domain binding(GO:0035500)
0.4	1.5	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.4	0.4	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.4	1.5	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3	1.0	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3	1.3	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.3	7.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.3	1.6	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.3	1.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3	0.9	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3	0.9	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.3	1.5	GO:0034046	poly(G) binding(GO:0034046)
0.3	4.9	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.3	1.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.3	0.8	GO:0070538	oleic acid binding(GO:0070538)
0.3	3.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.2	2.7	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.2	4.4	GO:0048185	activin binding(GO:0048185)
0.2	0.7	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2	1.0	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2	1.9	GO:0051425	PTB domain binding(GO:0051425)
0.2	0.9	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2	1.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.2	3.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2	1.5	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	1.4	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.2	0.8	GO:0019828	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2	0.6	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2	0.5	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.2	0.7	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.2	0.7	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.2	5.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	1.9	GO:0030274	LIM domain binding(GO:0030274)
0.2	2.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.2	1.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2	1.4	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.2	0.5	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2	0.9	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.1	1.6	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.4	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	3.4	GO:0017166	vinculin binding(GO:0017166)
0.1	0.8	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	1.1	GO:0001849	complement component C1q binding(GO:0001849)
0.1	1.1	GO:0034235	GPI anchor binding(GO:0034235)
0.1	0.8	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.5	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.9	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1	0.5	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1	0.8	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	4.6	GO:0005109	frizzled binding(GO:0005109)
0.1	0.6	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1	0.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	1.6	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	1.3	GO:0039706	co-receptor binding(GO:0039706)
0.1	2.5	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	2.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.3	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1	2.3	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.7	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	1.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	1.8	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.3	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	5.0	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.3	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.1	0.5	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	1.1	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.1	1.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	9.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.4	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.1	0.5	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	1.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.5	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.9	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.7	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	1.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.9	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.9	GO:0070569	uridylyltransferase activity(GO:0070569)
0.1	0.2	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.1	0.3	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1	1.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	1.5	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	2.9	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	4.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.4	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1	0.2	GO:0043398	HLH domain binding(GO:0043398)
0.1	2.0	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	1.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.5	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	1.9	GO:0001848	complement binding(GO:0001848)
0.1	1.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.3	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.2	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	0.4	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	0.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.1	1.7	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.6	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	1.9	GO:0015248	sterol transporter activity(GO:0015248)
0.1	0.6	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.7	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.2	GO:0047708	biotinidase activity(GO:0047708)
0.1	4.0	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	4.0	GO:0005507	copper ion binding(GO:0005507)
0.1	0.8	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.2	GO:0070026	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitric oxide binding(GO:0070026) nitrite reductase activity(GO:0098809)
0.1	0.6	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	3.0	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	5.2	GO:0008013	beta-catenin binding(GO:0008013)
0.1	0.3	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.1	0.9	GO:0031005	filamin binding(GO:0031005)
0.1	3.7	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	0.5	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.3	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.4	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.8	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.9	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.6	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	4.2	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.9	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	1.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	1.5	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.6	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	3.5	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.5	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	1.2	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	0.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	2.7	GO:0016879	ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0	0.9	GO:0030276	clathrin binding(GO:0030276)
0.0	1.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.5	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.8	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.5	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	1.0	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	1.9	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.1	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	2.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.6	GO:0003924	GTPase activity(GO:0003924)
0.0	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.5	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.0	2.0	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	2.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	2.0	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	1.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	1.4	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0070362	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.5	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.0	0.9	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0035240	dopamine binding(GO:0035240)
0.0	0.4	GO:0015485	cholesterol binding(GO:0015485)
0.0	2.6	GO:0051082	unfolded protein binding(GO:0051082)
0.0	1.6	GO:0046332	SMAD binding(GO:0046332)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0016160	amylase activity(GO:0016160)
0.0	0.4	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.3	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.6	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.4	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	2.4	GO:0001047	core promoter binding(GO:0001047)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.9	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	2.2	GO:0005125	cytokine activity(GO:0005125)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215) phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.9	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	2.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	3.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.6	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	2.6	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	4.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	3.8	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.9	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.7	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	1.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.6	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.8	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	3.0	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	2.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.0	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	3.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	3.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	1.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.5	32.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.5	6.8	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.4	6.0	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.4	0.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.4	1.6	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.4	2.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.4	0.4	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.4	15.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.4	0.4	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.4	11.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3	11.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.3	7.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3	8.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	5.0	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.3	17.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.3	6.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.3	0.5	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.3	4.4	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3	2.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.3	2.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.3	0.8	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.2	3.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	3.9	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	3.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	2.0	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2	3.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	9.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	25.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	3.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	4.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.2	3.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.2	4.9	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.2	1.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.2	4.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	2.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	2.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	8.0	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.2	0.9	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	3.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2	4.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	6.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.2	5.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	4.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.2	5.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	1.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2	1.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	3.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	1.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2	0.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	5.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	3.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.2	2.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2	5.8	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.2	3.7	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.2	2.9	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	7.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	2.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	3.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	1.4	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.1	0.6	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	1.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	2.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	2.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	0.5	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	7.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	1.8	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	2.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	5.2	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1	4.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	4.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	3.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	2.2	REACTOME TRANSCRIPTION COUPLED NER TC NER	Genes involved in Transcription-coupled NER (TC-NER)
0.1	1.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	2.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	1.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.0	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	1.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	1.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.6	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	4.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	3.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.7	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	2.5	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	4.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	3.6	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	4.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	2.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.8	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	0.5	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.1	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	7.5	REACTOME G1 S TRANSITION	Genes involved in G1/S Transition
0.1	1.0	REACTOME OPSINS	Genes involved in Opsins
0.1	1.8	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.0	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	1.0	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	0.7	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.7	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	3.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	2.0	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	0.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	2.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	0.4	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.1	0.4	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.6	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.2	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1	1.0	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	7.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.5	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	0.5	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1	0.3	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1	0.7	REACTOME GPCR LIGAND BINDING	Genes involved in GPCR ligand binding
0.1	0.5	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.1	3.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	1.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	4.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1	2.1	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1	2.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	1.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	1.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	1.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	0.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	1.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	8.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.8	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	3.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.8	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.6	REACTOME CELL CELL COMMUNICATION	Genes involved in Cell-Cell communication
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	4.7	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	3.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.6	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.2	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	5.6	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	2.0	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	4.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.2	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME S PHASE	Genes involved in S Phase
0.0	0.2	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.0	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.1	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.7	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.8	REACTOME DNA REPLICATION	Genes involved in DNA Replication
0.0	0.1	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	9.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.6	1.8	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.4	2.1	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2	1.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2	2.4	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2	0.9	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.2	0.9	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.2	6.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	0.6	GO:0019981	interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) interleukin-6 binding(GO:0019981)
0.2	1.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	1.5	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.2	7.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.2	0.5	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	1.6	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.5	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1	2.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.8	GO:0043426	MRF binding(GO:0043426)
0.1	0.3	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1	1.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.4	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1	0.2	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.1	2.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	1.9	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	2.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.5	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	0.9	GO:0015250	water channel activity(GO:0015250)
0.1	1.0	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.2	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.1	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.4	GO:0032190	acrosin binding(GO:0032190)
0.0	1.0	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.3	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	3.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.4	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.6	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0	0.9	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.8	GO:0005109	frizzled binding(GO:0005109)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	1.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0005113	patched binding(GO:0005113)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.5	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.6	GO:0070888	E-box binding(GO:0070888)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.3	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	1.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0	0.1	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.9	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.4	9.0	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	1.2	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2	1.9	GO:0032010	phagolysosome(GO:0032010)
0.2	1.1	GO:0036398	TCR signalosome(GO:0036398)
0.2	1.2	GO:0042825	TAP complex(GO:0042825)
0.2	0.5	GO:0031251	PAN complex(GO:0031251)
0.1	2.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	1.0	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.7	GO:0031905	early endosome lumen(GO:0031905)
0.1	0.8	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.1	1.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.4	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.5	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.7	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.1	0.3	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	1.3	GO:0005916	fascia adherens(GO:0005916)
0.1	1.5	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	0.3	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1	0.5	GO:0000322	storage vacuole(GO:0000322)
0.1	1.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.9	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.9	GO:0005922	connexon complex(GO:0005922)
0.1	0.2	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0	0.5	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.0	0.3	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	0.1	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	0.2	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.0	0.2	GO:0032584	growth cone membrane(GO:0032584)
0.0	1.3	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.4	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.9	GO:0000145	exocyst(GO:0000145)
0.0	0.2	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.3	GO:0045179	apical cortex(GO:0045179)
0.0	0.5	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.4	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.5	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0045298	tubulin complex(GO:0045298)
0.0	0.5	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.0	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	1.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.1	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.1	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	0.3	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.7	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	1.2	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.6	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.4	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.3	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	1.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.7	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.6	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.6	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.2	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	1.7	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.0	GO:0034455	t-UTP complex(GO:0034455)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.6	GO:0031904	endosome lumen(GO:0031904)
0.0	0.2	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.9	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	1.5	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	2.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	0.5	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	2.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	2.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	2.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	1.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	2.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.4	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.7	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	7.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	2.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	3.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.5	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
0.3	1.6	GO:2000468	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.3	1.0	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.3	2.9	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.3	0.9	GO:0060620	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.3	0.9	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.3	1.8	GO:1902847	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3	0.9	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3	1.2	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.3	0.9	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3	2.5	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3	0.8	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2	0.9	GO:0044861	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.2	0.8	GO:0001757	somite specification(GO:0001757)
0.2	0.4	GO:0048145	fibroblast proliferation(GO:0048144) regulation of fibroblast proliferation(GO:0048145)
0.2	0.9	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2	1.6	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2	0.5	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.2	1.5	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.2	0.2	GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2	0.3	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.2	0.5	GO:0003383	apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
0.2	0.6	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.2	0.8	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.2	0.9	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.6	GO:0009956	radial pattern formation(GO:0009956)
0.1	0.6	GO:0034959	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1	1.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	1.5	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.4	GO:0016095	polyprenol catabolic process(GO:0016095)
0.1	2.6	GO:0001765	membrane raft assembly(GO:0001765)
0.1	0.6	GO:0061107	seminal vesicle development(GO:0061107)
0.1	1.8	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.4	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.1	0.3	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.1	1.4	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.4	GO:2000426	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1	0.2	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.1	0.5	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	0.6	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.5	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.7	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.4	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.3	GO:0019836	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1	0.3	GO:0070428	negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1	0.9	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1	0.9	GO:0001887	selenium compound metabolic process(GO:0001887)
0.1	0.9	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.9	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	0.5	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.1	0.4	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.1	0.3	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1	0.1	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.1	0.1	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	1.2	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	0.2	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1	0.4	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.2	GO:0021558	midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558)
0.1	0.2	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.1	0.1	GO:1900244	positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.1	0.2	GO:0097359	UDP-glucosylation(GO:0097359)
0.1	0.7	GO:1902416	positive regulation of mRNA binding(GO:1902416)
0.1	0.9	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.3	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	0.3	GO:0060356	leucine import(GO:0060356)
0.1	0.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.7	GO:0007498	mesoderm development(GO:0007498)
0.1	0.1	GO:0032242	regulation of nucleoside transport(GO:0032242)
0.1	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	0.3	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	2.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.2	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.1	0.6	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.1	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.1	0.2	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.1	0.1	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1	0.2	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1	0.2	GO:1900158	positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1	0.1	GO:0050918	positive chemotaxis(GO:0050918)
0.1	1.2	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.2	GO:0061760	antifungal innate immune response(GO:0061760)
0.1	0.4	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.2	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.1	0.2	GO:1990637	response to prolactin(GO:1990637)
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.9	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.1	0.2	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	0.4	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.5	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.1	1.7	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.1	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.0	1.1	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.3	GO:0030035	microspike assembly(GO:0030035)
0.0	0.1	GO:0075044	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0	0.3	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0	0.2	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0	0.3	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.4	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	1.2	GO:0007567	parturition(GO:0007567)
0.0	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:1904579	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0	0.3	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0	0.2	GO:1903566	ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0	0.2	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.1	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
0.0	0.2	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	1.2	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.2	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.2	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.0	0.6	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.0	0.2	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0	0.2	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
0.0	0.1	GO:1903365	regulation of fear response(GO:1903365) regulation of behavioral fear response(GO:2000822)
0.0	0.2	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0	0.5	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.5	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.0	0.0	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.5	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	1.0	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.6	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.5	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.2	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.0	0.1	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
0.0	0.1	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0	0.1	GO:0032571	response to vitamin K(GO:0032571) response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0	0.1	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	0.8	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	0.1	GO:0018874	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.1	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0	0.1	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.2	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.2	GO:0033384	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0	0.1	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.0	0.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.2	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.0	0.4	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0	0.1	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
0.0	0.4	GO:0002002	regulation of angiotensin levels in blood(GO:0002002) angiotensin maturation(GO:0002003) regulation of angiotensin metabolic process(GO:0060177)
0.0	1.8	GO:0006953	acute-phase response(GO:0006953)
0.0	0.4	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	0.2	GO:2000609	regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.1	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0051344	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0038098	sequestering of BMP in extracellular matrix(GO:0035582) sequestering of BMP from receptor via BMP binding(GO:0038098) negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.1	GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0	0.2	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.2	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.2	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.8	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.1	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0	0.7	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.5	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.0	0.1	GO:2000395	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0	0.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.3	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	0.1	GO:0090024	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0	0.1	GO:0015862	uridine transport(GO:0015862)
0.0	0.1	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.0	0.1	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0	0.2	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.6	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.2	GO:0048477	oogenesis(GO:0048477)
0.0	0.3	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.5	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.1	GO:0042700	luteinizing hormone signaling pathway(GO:0042700)
0.0	0.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.3	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.7	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.5	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
0.0	0.0	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:1902023	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0	0.3	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.4	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.1	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.2	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.2	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.0	GO:0007356	thorax and anterior abdomen determination(GO:0007356)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621)
0.0	0.1	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.0	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.0	0.1	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.1	GO:0045829	negative regulation of isotype switching(GO:0045829)
0.0	0.1	GO:0019348	dolichol metabolic process(GO:0019348)
0.0	0.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:2000254	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.2	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.2	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.7	GO:1903169	regulation of calcium ion transmembrane transport(GO:1903169)
0.0	0.6	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.2	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.0	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.0	0.1	GO:0014038	regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
0.0	0.1	GO:0051410	detoxification of nitrogen compound(GO:0051410)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0051510	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0	0.1	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
0.0	0.0	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.0	0.1	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.1	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.1	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.0	0.4	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.0	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	0.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.0	GO:1901628	positive regulation of postsynaptic membrane organization(GO:1901628)
0.0	0.1	GO:0007619	courtship behavior(GO:0007619)
0.0	0.2	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.6	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.0	GO:0018307	enzyme active site formation(GO:0018307) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.4	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:1904351	negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0	0.0	GO:0051459	regulation of corticotropin secretion(GO:0051459)
0.0	0.7	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.6	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.4	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.6	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.0	0.4	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.3	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.4	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.1	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.0	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.1	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.1	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.0	0.2	GO:0042423	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.7	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.1	GO:0014029	neural crest formation(GO:0014029)
0.0	0.1	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.1	GO:0090208	positive regulation of triglyceride biosynthetic process(GO:0010867) positive regulation of triglyceride metabolic process(GO:0090208)
0.0	0.3	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.0	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.0	0.2	GO:0090190	positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.0	0.1	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0071267	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0015692	lead ion transport(GO:0015692)
0.0	0.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.1	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.2	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.0	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.0	0.0	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0009181	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0	0.2	GO:0048265	response to pain(GO:0048265)
0.0	0.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.0	GO:0071301	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0	0.0	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	13.9	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
3.1	9.3	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.2	4.7	GO:0007525	somatic muscle development(GO:0007525)
1.1	4.3	GO:0035995	detection of muscle stretch(GO:0035995)
1.0	8.3	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.7	3.0	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.6	2.3	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.5	2.6	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.5	1.4	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.4	1.6	GO:0002317	plasma cell differentiation(GO:0002317)
0.4	1.6	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.4	0.4	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.3	2.5	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.3	0.9	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.3	1.2	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.3	1.4	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.3	3.8	GO:0006527	arginine catabolic process(GO:0006527)
0.2	3.1	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.2	1.9	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.2	1.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.2	0.8	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.2	0.6	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2	1.8	GO:0042373	vitamin K metabolic process(GO:0042373)
0.2	0.2	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2	0.5	GO:0048627	myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.2	6.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.2	2.8	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.5	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	1.7	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.3	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.1	0.4	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1	0.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	0.3	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	3.2	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.7	GO:0090131	mesenchyme migration(GO:0090131)
0.1	1.0	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.3	GO:0097056	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	0.3	GO:0060437	lung growth(GO:0060437)
0.1	1.1	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.1	0.3	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.1	0.5	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.1	0.3	GO:0045062	extrathymic T cell selection(GO:0045062)
0.1	0.3	GO:0036466	synaptic vesicle recycling via endosome(GO:0036466)
0.1	0.7	GO:1902915	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	1.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	2.4	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.4	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.7	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.1	0.6	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.1	0.6	GO:0031642	negative regulation of myelination(GO:0031642)
0.1	0.2	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.4	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	1.2	GO:0048535	lymph node development(GO:0048535)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.4	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.6	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1	0.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.9	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.1	0.7	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	3.4	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	0.6	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.4	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	1.0	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1	0.3	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.1	0.2	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1	0.3	GO:0035524	proline transmembrane transport(GO:0035524)
0.1	0.4	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0	0.2	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.0	0.3	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.4	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	1.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.9	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0060796	regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0	0.2	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.2	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0	2.5	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.6	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	1.8	GO:0031529	ruffle organization(GO:0031529)
0.0	1.1	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.3	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.9	GO:0035994	response to muscle stretch(GO:0035994)
0.0	0.5	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.2	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	1.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.6	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	1.7	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.6	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	1.3	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.2	GO:0014901	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.7	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.5	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.3	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.3	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0071415	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	0.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.8	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.7	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.3	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.6	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	1.4	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.3	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.4	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.4	GO:0072431	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	1.6	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.4	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.2	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.5	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	1.5	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.1	GO:0070543	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0	0.0	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.1	GO:0001554	luteolysis(GO:0001554)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0070495	negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.6	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.8	GO:0042643	actomyosin, actin portion(GO:0042643)
0.7	3.4	GO:1990425	ryanodine receptor complex(GO:1990425)
0.5	4.2	GO:0005610	laminin-5 complex(GO:0005610)
0.4	2.0	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.4	5.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4	3.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.3	9.4	GO:0030057	desmosome(GO:0030057)
0.2	2.3	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.6	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.5	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	1.4	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.7	GO:0005638	lamin filament(GO:0005638)
0.1	0.9	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.8	GO:0097443	sorting endosome(GO:0097443)
0.1	0.6	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.4	GO:0031415	NatA complex(GO:0031415)
0.1	0.8	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	7.5	GO:0031902	late endosome membrane(GO:0031902)
0.1	0.4	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	0.3	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.1	GO:0070557	PCNA-p21 complex(GO:0070557)
0.0	1.7	GO:0032420	stereocilium(GO:0032420)
0.0	0.5	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	1.9	GO:0031941	filamentous actin(GO:0031941)
0.0	2.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.6	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	0.4	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	1.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	3.2	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0	0.4	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.6	GO:0097542	ciliary tip(GO:0097542)
0.0	0.4	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	1.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.8	GO:0018995	host(GO:0018995) host cell(GO:0043657)
0.0	0.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	1.1	GO:0005768	endosome(GO:0005768)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.9	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.8	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.4	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.5	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	1.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	11.5	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	2.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	19.6	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.2	16.9	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	5.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	12.4	PID BCR 5PATHWAY	BCR signaling pathway
0.1	5.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	3.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	4.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	4.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	4.9	PID AURORA A PATHWAY	Aurora A signaling
0.1	0.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	3.3	PID ATM PATHWAY	ATM pathway
0.1	1.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	2.9	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.8	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.8	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	3.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.8	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	2.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.9	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	2.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	2.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.1	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.7	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	2.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.8	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	2.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	5.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	2.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	2.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.1	3.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	6.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	4.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	2.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.8	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	1.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	2.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	3.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	2.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	3.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	1.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	2.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.2	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.0	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.7	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	5.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	2.0	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.9	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.8	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.9	PID IL23 PATHWAY	IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	0.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.6	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.3	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	2.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5	5.9	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.5	1.4	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.5	2.3	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.5	1.4	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.4	1.6	GO:0035026	leading edge cell differentiation(GO:0035026)
0.4	1.9	GO:0048539	bone marrow development(GO:0048539)
0.3	1.0	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.3	0.9	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.3	2.0	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3	0.8	GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.3	2.5	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3	1.5	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.2	1.0	GO:0000103	sulfate assimilation(GO:0000103)
0.2	1.7	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.2	0.7	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2	1.0	GO:0009956	radial pattern formation(GO:0009956)
0.2	0.6	GO:0071529	cementum mineralization(GO:0071529)
0.2	0.6	GO:0010645	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2	0.6	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.2	0.2	GO:0003289	septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
0.2	0.8	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.2	1.3	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.2	1.8	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2	0.9	GO:0021649	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2	0.7	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	1.0	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2	0.8	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	0.5	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
0.2	0.6	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2	0.9	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.2	0.9	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	3.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.2	1.5	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2	0.8	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.1	1.3	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.7	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	0.5	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1	0.4	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1	0.5	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	0.4	GO:1904647	response to rotenone(GO:1904647)
0.1	0.9	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	0.7	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.6	GO:1900127	renal water absorption(GO:0070295) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.1	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1	0.5	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.7	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.7	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1	0.9	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.1	0.8	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.5	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.1	1.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.5	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1	0.3	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	0.2	GO:0014734	skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	0.4	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.8	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.3	GO:1900158	negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1	0.3	GO:1901535	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1	3.3	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.3	GO:0021569	rhombomere 3 development(GO:0021569)
0.1	1.1	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.5	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.6	GO:0032596	protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.1	0.5	GO:1902617	response to fluoride(GO:1902617)
0.1	0.1	GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1	0.5	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.2	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	0.4	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.8	GO:0015889	cobalamin transport(GO:0015889)
0.1	1.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.1	0.3	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.1	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	0.5	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	0.3	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1	0.3	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.1	0.6	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	1.3	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.2	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.3	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.1	0.4	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.6	GO:0006528	asparagine metabolic process(GO:0006528)
0.1	0.2	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1	0.3	GO:0006710	androgen catabolic process(GO:0006710)
0.1	0.2	GO:0061055	myotome development(GO:0061055)
0.1	0.3	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	0.7	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.1	0.5	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.5	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	1.2	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.4	GO:0015862	uridine transport(GO:0015862)
0.1	1.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	1.9	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.4	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.1	0.2	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1	0.3	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.4	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1	0.9	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.4	GO:0001765	membrane raft assembly(GO:0001765)
0.1	0.5	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.5	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1	1.6	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.7	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	0.2	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.2	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.7	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.2	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.4	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.2	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	0.4	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.2	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1	0.3	GO:0021814	cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.1	0.8	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.1	0.2	GO:0016925	protein sumoylation(GO:0016925)
0.1	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.2	GO:0090135	actin filament branching(GO:0090135) protein localization to cell leading edge(GO:1902463)
0.1	0.3	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1	0.2	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.1	2.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.7	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.2	GO:1902462	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1	0.2	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.2	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1	0.4	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1	0.2	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.5	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	0.3	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.4	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.1	GO:1900157	iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) regulation of bone mineralization involved in bone maturation(GO:1900157) positive regulation of bone mineralization involved in bone maturation(GO:1900159) positive regulation of bone development(GO:1903012) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0	1.1	GO:0043586	tongue development(GO:0043586)
0.0	0.3	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.7	GO:0070307	lens fiber cell development(GO:0070307)
0.0	1.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.5	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.2	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.2	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.0	0.3	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0	0.2	GO:0042713	sperm ejaculation(GO:0042713)
0.0	0.3	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	2.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.1	GO:0001897	cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.2	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.0	0.4	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.4	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.0	0.4	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.0	0.3	GO:1904550	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0	0.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.0	0.2	GO:2001153	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0	0.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.2	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0	1.2	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.7	GO:0001780	neutrophil homeostasis(GO:0001780)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.2	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0	0.1	GO:0007497	posterior midgut development(GO:0007497) positive regulation of penile erection(GO:0060406) endothelin receptor signaling pathway(GO:0086100)
0.0	0.4	GO:0051451	myoblast migration(GO:0051451)
0.0	1.3	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.5	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.2	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.0	0.3	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.8	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	1.0	GO:0097503	sialylation(GO:0097503)
0.0	1.0	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.4	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:1903487	regulation of lactation(GO:1903487)
0.0	0.2	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
0.0	8.6	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	1.0	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.3	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.1	GO:1902856	negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	6.1	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.1	GO:2001162	histone H3-K79 methylation(GO:0034729) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0	0.2	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.1	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.0	0.1	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.0	0.2	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0	0.2	GO:0006311	meiotic gene conversion(GO:0006311)
0.0	0.1	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.0	0.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.4	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.3	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.5	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.1	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0	0.4	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	0.3	GO:0051315	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.2	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.1	GO:1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	4.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.2	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.6	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.4	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.1	GO:0036363	transforming growth factor beta activation(GO:0036363)
0.0	0.4	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.9	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.5	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0010909	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:0018874	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.2	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.2	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.4	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.0	0.0	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.1	GO:0009189	dTTP biosynthetic process(GO:0006235) deoxyribonucleoside diphosphate metabolic process(GO:0009186) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0	0.4	GO:0002003	angiotensin maturation(GO:0002003)
0.0	0.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	0.6	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.1	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.0	GO:0072019	proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.3	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0	0.4	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.2	GO:1904646	cellular response to beta-amyloid(GO:1904646)
0.0	0.0	GO:0061739	protein lipidation involved in autophagosome assembly(GO:0061739)
0.0	0.1	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.2	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.2	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.1	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.1	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.0	0.4	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0002643	regulation of tolerance induction(GO:0002643)
0.0	0.1	GO:0050668	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0	0.1	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0	0.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.2	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.2	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.8	GO:0045026	plasma membrane fusion(GO:0045026)
0.0	0.1	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.0	0.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0043323	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0	0.3	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0032621	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0003183	mitral valve development(GO:0003174) mitral valve morphogenesis(GO:0003183)
0.0	0.3	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:0045324	late endosome to vacuole transport(GO:0045324)
0.0	0.0	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0019732	antifungal humoral response(GO:0019732)
0.0	0.0	GO:0021766	hippocampus development(GO:0021766)
0.0	0.1	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.3	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.2	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.1	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.0	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.1	GO:0042428	serotonin metabolic process(GO:0042428)
0.0	0.1	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.0	0.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.1	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.2	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.0	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	2.0	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.1	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0	0.3	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.0	0.1	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.4	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.1	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.2	GO:0043243	positive regulation of protein complex disassembly(GO:0043243)
0.0	0.1	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.0	0.0	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.1	GO:0044275	cellular carbohydrate catabolic process(GO:0044275)
0.0	0.0	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.4	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.2	GO:0030593	neutrophil chemotaxis(GO:0030593)
0.0	0.3	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.4	GO:0060411	cardiac septum morphogenesis(GO:0060411)
0.0	0.1	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.1	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	0.1	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.0	0.0	GO:1990641	response to iron ion starvation(GO:1990641)
0.0	0.9	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.0	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.4	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.5	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.2	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.0	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.0	0.1	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.0	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0	0.0	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	1.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	2.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	1.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	5.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.0	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	2.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	4.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.1	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	1.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.7	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.7	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	4.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.6	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	1.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.1	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.5	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	8.4	GO:0097208	alveolar lamellar body(GO:0097208)
0.5	4.6	GO:0097413	Lewy body(GO:0097413)
0.5	1.8	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3	6.3	GO:0031083	BLOC-1 complex(GO:0031083)
0.3	2.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.3	1.6	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.3	1.3	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.3	1.8	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3	1.4	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.2	2.0	GO:0000322	storage vacuole(GO:0000322)
0.2	2.0	GO:0000439	core TFIIH complex(GO:0000439)
0.2	1.0	GO:0033263	CORVET complex(GO:0033263)
0.2	0.7	GO:0070695	FHF complex(GO:0070695)
0.2	2.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.7	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.5	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	1.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.1	0.4	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.1	0.9	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	0.4	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	0.6	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.3	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.1	1.1	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.1	1.8	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.3	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	1.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	2.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	1.0	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.1	GO:0005916	fascia adherens(GO:0005916)
0.1	0.5	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.5	GO:0097452	GAIT complex(GO:0097452)
0.1	0.4	GO:0005901	caveola(GO:0005901)
0.1	0.2	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1	0.9	GO:0097227	sperm annulus(GO:0097227)
0.1	0.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.7	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1	0.4	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.3	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	0.4	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.3	GO:0033503	HULC complex(GO:0033503)
0.1	0.9	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.6	GO:0030478	actin cap(GO:0030478)
0.0	7.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.7	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.6	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.0	0.8	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.4	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.4	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.1	GO:0035838	growing cell tip(GO:0035838)
0.0	0.4	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.3	GO:0071203	WASH complex(GO:0071203)
0.0	0.3	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	0.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.9	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.6	GO:0031143	pseudopodium(GO:0031143)
0.0	1.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.4	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	2.0	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.4	GO:0032155	cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0	0.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	0.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	8.1	GO:0005938	cell cortex(GO:0005938)
0.0	1.8	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.3	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	0.6	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.3	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	1.4	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.3	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.6	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.2	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	0.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.0	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.1	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.3	GO:0008021	synaptic vesicle(GO:0008021)
0.0	0.4	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.5	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.2	GO:0097342	ripoptosome(GO:0097342)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.0	GO:0031082	BLOC complex(GO:0031082)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.9	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.1	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2	10.7	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.2	10.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	5.2	REACTOME KINESINS	Genes involved in Kinesins
0.2	3.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	3.8	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.2	4.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	4.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	2.7	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	6.2	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	2.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	6.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	5.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	2.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	2.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	2.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	2.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	3.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	2.7	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	2.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	1.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	1.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	5.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.7	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	1.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	0.8	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	3.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	1.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.3	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	1.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.7	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.9	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.8	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	1.2	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	1.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	1.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.6	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	2.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	6.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	1.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	1.6	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1	1.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	2.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	1.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	1.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	1.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	3.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	1.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	1.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.5	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	1.2	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	9.6	GO:0002086	maltose metabolic process(GO:0000023) diaphragm contraction(GO:0002086)
1.9	5.6	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
1.6	4.9	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.6	4.8	GO:1902445	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.5	6.0	GO:0043323	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.4	12.9	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
1.2	5.8	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
1.1	1.1	GO:0050787	detoxification of mercury ion(GO:0050787)
1.1	7.7	GO:0018158	protein oxidation(GO:0018158)
1.0	6.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.9	9.0	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.9	2.7	GO:0035978	mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.7	2.1	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.6	2.6	GO:0015808	L-alanine transport(GO:0015808)
0.6	1.7	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.6	2.3	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.6	8.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.5	4.4	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.5	4.2	GO:0006526	arginine biosynthetic process(GO:0006526)
0.5	1.5	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.5	1.5	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.5	1.4	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.4	1.8	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.4	4.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.4	1.8	GO:0061528	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.4	2.6	GO:0071873	response to norepinephrine(GO:0071873)
0.4	1.3	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.4	1.3	GO:0061227	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.4	1.7	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.4	2.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.4	1.7	GO:0015811	L-cystine transport(GO:0015811)
0.4	2.0	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.4	7.3	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.4	2.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.4	1.5	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4	1.1	GO:0060535	trachea cartilage morphogenesis(GO:0060535)
0.4	2.2	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3	1.0	GO:0061055	myotome development(GO:0061055)
0.3	1.4	GO:0019087	transformation of host cell by virus(GO:0019087)
0.3	1.6	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.3	3.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.3	0.9	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.3	1.2	GO:1905123	regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.3	1.2	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.3	0.9	GO:0003285	septum secundum development(GO:0003285)
0.3	3.5	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.3	8.4	GO:0006884	cell volume homeostasis(GO:0006884)
0.3	0.9	GO:0006258	UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.3	1.7	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.3	2.0	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.3	1.1	GO:1901804	glucosylceramide catabolic process(GO:0006680) termination of signal transduction(GO:0023021) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.3	0.8	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3	0.8	GO:0043317	regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318) insulin catabolic process(GO:1901143)
0.3	3.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.3	0.5	GO:1903936	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.3	0.8	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.3	0.5	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3	0.8	GO:0035606	induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.3	3.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.3	2.0	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.2	0.7	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2	0.7	GO:0097359	UDP-glucosylation(GO:0097359)
0.2	1.2	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.2	0.9	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.2	2.4	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.2	1.5	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.2	1.0	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.2	1.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.2	1.9	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	1.3	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.2	0.6	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.2	1.5	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2	1.1	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
0.2	0.2	GO:1903056	regulation of melanosome organization(GO:1903056)
0.2	1.8	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2	0.7	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	1.4	GO:1903874	ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.2	1.6	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.2	1.2	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.2	1.2	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.2	1.7	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.2	0.9	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.2	0.5	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2	0.5	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2	2.6	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.2	0.5	GO:0060592	mammary gland formation(GO:0060592)
0.2	0.5	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.2	0.8	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2	0.5	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2	2.8	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.2	0.6	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2	0.8	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.2	0.8	GO:0090650	rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2	2.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0051031	tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1	0.9	GO:0070560	protein secretion by platelet(GO:0070560)
0.1	0.4	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	1.3	GO:0009414	response to water deprivation(GO:0009414)
0.1	1.0	GO:0042415	norepinephrine metabolic process(GO:0042415) surfactant homeostasis(GO:0043129)
0.1	1.0	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.1	0.6	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.1	1.6	GO:0015886	heme transport(GO:0015886)
0.1	0.1	GO:0002188	translation reinitiation(GO:0002188)
0.1	1.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.7	GO:0036369	transcription factor catabolic process(GO:0036369)
0.1	0.4	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.8	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
0.1	1.1	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.1	0.3	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.1	0.9	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1	0.3	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	3.4	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.6	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.5	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	0.6	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	3.1	GO:0030220	platelet formation(GO:0030220)
0.1	0.5	GO:0042360	vitamin E metabolic process(GO:0042360)
0.1	0.3	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1	0.6	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.1	0.5	GO:0043335	protein unfolding(GO:0043335)
0.1	2.8	GO:0007567	parturition(GO:0007567)
0.1	0.4	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	0.7	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	2.5	GO:0003334	keratinocyte development(GO:0003334)
0.1	1.6	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1	1.2	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	0.3	GO:0001207	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1	1.8	GO:0043485	endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1	0.8	GO:0030043	actin filament fragmentation(GO:0030043)
0.1	1.6	GO:0016042	lipid catabolic process(GO:0016042)
0.1	0.3	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.1	1.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.1	0.3	GO:0002752	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1	2.6	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1	0.6	GO:0006824	cobalt ion transport(GO:0006824)
0.1	0.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	1.5	GO:0006558	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.3	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.1	0.7	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	1.0	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	0.6	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	0.3	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.5	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.8	GO:0006069	ethanol oxidation(GO:0006069)
0.1	0.4	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.1	0.9	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.4	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	2.4	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.1	0.8	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.5	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1	2.1	GO:0051447	negative regulation of meiotic cell cycle(GO:0051447)
0.1	0.9	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1	4.8	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	4.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	3.4	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.1	0.7	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	1.6	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.1	1.3	GO:0000338	protein deneddylation(GO:0000338)
0.1	0.6	GO:0000724	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1	1.6	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.6	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.1	0.5	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	0.2	GO:1901526	positive regulation of macromitophagy(GO:1901526) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1	0.6	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.1	0.5	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	1.4	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.1	1.6	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.1	2.5	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.7	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.1	5.9	GO:0046324	regulation of glucose import(GO:0046324)
0.1	0.8	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	0.5	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.2	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.5	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	2.1	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	0.6	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	3.9	GO:0006953	acute-phase response(GO:0006953)
0.1	0.3	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.1	1.3	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.1	0.3	GO:2000254	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.1	0.3	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.1	0.5	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.2	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1	0.2	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.2	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.1	0.3	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	0.3	GO:0046618	drug export(GO:0046618)
0.1	0.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.9	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	1.1	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1	1.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.3	GO:0016240	autophagosome docking(GO:0016240)
0.1	0.8	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	0.3	GO:0021546	rhombomere development(GO:0021546)
0.1	0.2	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0	0.1	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0	1.1	GO:0010669	epithelial structure maintenance(GO:0010669)
0.0	0.2	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.2	GO:1902430	negative regulation of beta-amyloid formation(GO:1902430)
0.0	0.2	GO:1904327	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0	0.2	GO:0032898	nerve growth factor processing(GO:0032455) neurotrophin production(GO:0032898)
0.0	0.3	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.0	0.2	GO:0046203	spermidine catabolic process(GO:0046203)
0.0	0.4	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.0	0.6	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.4	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.5	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.5	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.3	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.4	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.0	0.6	GO:0043586	tongue development(GO:0043586)
0.0	1.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.4	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.2	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.1	GO:1904578	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.0	0.5	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.2	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.0	0.2	GO:0060539	diaphragm development(GO:0060539)
0.0	0.5	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0	2.5	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.3	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.6	GO:0016264	gap junction assembly(GO:0016264)
0.0	2.9	GO:0042795	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	1.6	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	1.1	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0	1.2	GO:0097178	ruffle assembly(GO:0097178)
0.0	1.1	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.3	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.3	GO:0043401	steroid hormone mediated signaling pathway(GO:0043401)
0.0	0.5	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.5	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.1	GO:0015677	copper ion import(GO:0015677)
0.0	0.2	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.4	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.4	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.1	GO:0007270	neuron-neuron synaptic transmission(GO:0007270)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.1	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.0	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.3	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.5	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.2	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	2.1	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.8	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.2	GO:0031647	regulation of protein stability(GO:0031647)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.6	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	1.1	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.1	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.0	0.1	GO:1904616	regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0	0.7	GO:0071625	vocalization behavior(GO:0071625)
0.0	1.4	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.1	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.2	GO:0021603	cranial nerve formation(GO:0021603)
0.0	1.3	GO:0019915	lipid storage(GO:0019915)
0.0	0.3	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.3	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.7	GO:0097421	liver regeneration(GO:0097421)
0.0	0.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.4	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.4	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.0	0.9	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.0	0.3	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:0032679	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0	0.1	GO:0007538	primary sex determination(GO:0007538)
0.0	0.5	GO:1904376	negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	2.2	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.4	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514)
0.0	0.2	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.6	GO:0006921	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0009386	translational attenuation(GO:0009386)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.3	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.3	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.0	0.2	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.8	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.2	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.6	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.4	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.0	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.0	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.1	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.2	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.6	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.2	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.3	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) spongiotrophoblast differentiation(GO:0060708)
0.0	0.4	GO:0009268	response to pH(GO:0009268)
0.0	0.1	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.7	GO:0048477	oogenesis(GO:0048477)
0.0	0.6	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	0.3	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.6	GO:0030818	negative regulation of cAMP biosynthetic process(GO:0030818)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.3	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.3	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	2.6	GO:0006457	protein folding(GO:0006457)
0.0	0.0	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.7	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.4	GO:0050909	sensory perception of taste(GO:0050909)
0.0	0.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.3	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.6	1.8	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.6	1.7	GO:0033341	regulation of collagen binding(GO:0033341)
0.5	2.6	GO:0002159	desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.5	2.0	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.4	1.7	GO:0044375	regulation of peroxisome size(GO:0044375)
0.4	2.0	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.4	1.1	GO:0019482	purine nucleobase catabolic process(GO:0006145) beta-alanine metabolic process(GO:0019482)
0.3	1.2	GO:0032972	diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.3	2.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3	1.6	GO:0010734	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3	4.1	GO:0051639	actin filament network formation(GO:0051639)
0.3	1.3	GO:0072244	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2	0.7	GO:0071698	olfactory placode formation(GO:0030910) myotome development(GO:0061055) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2	1.2	GO:0030047	actin modification(GO:0030047)
0.2	1.2	GO:0015961	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2	0.7	GO:0032474	otolith morphogenesis(GO:0032474)
0.2	1.8	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.2	1.1	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.2	1.7	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.2	1.0	GO:1900107	embryonic hindgut morphogenesis(GO:0048619) regulation of nodal signaling pathway(GO:1900107)
0.1	0.6	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.1	1.6	GO:0000733	DNA strand renaturation(GO:0000733)
0.1	1.0	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	1.5	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1	1.2	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	0.4	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1	0.7	GO:0031017	exocrine pancreas development(GO:0031017)
0.1	0.5	GO:0060356	leucine import(GO:0060356)
0.1	0.3	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1	0.5	GO:1903412	response to bile acid(GO:1903412)
0.1	0.4	GO:0002545	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1	0.5	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.1	0.3	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	1.8	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1	0.5	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
0.1	2.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.1	0.3	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.8	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	0.6	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.3	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1	1.4	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	0.8	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	1.4	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.6	GO:0060174	limb bud formation(GO:0060174)
0.0	1.8	GO:0016577	histone demethylation(GO:0016577)
0.0	0.1	GO:0042938	dipeptide transport(GO:0042938)
0.0	0.3	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0042369	vitamin D catabolic process(GO:0042369)
0.0	0.5	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.3	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.3	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.0	0.3	GO:0030308	negative regulation of cell growth(GO:0030308)
0.0	0.5	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	8.6	GO:0043542	endothelial cell migration(GO:0043542)
0.0	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.3	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.5	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.2	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	1.5	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.5	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.9	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.4	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	1.5	GO:0035904	aorta development(GO:0035904)
0.0	2.3	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.5	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.3	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.6	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	1.0	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.3	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.7	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.1	GO:0097350	neutrophil clearance(GO:0097350)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.4	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.4	GO:0043473	pigmentation(GO:0043473)
0.0	0.4	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	1.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.9	GO:0030282	bone mineralization(GO:0030282)
0.0	0.0	GO:0031627	telomeric loop formation(GO:0031627) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0	0.7	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.0	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0	0.1	GO:0042982	amyloid precursor protein metabolic process(GO:0042982)
0.0	0.9	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0	0.5	GO:0010824	regulation of centrosome duplication(GO:0010824)
0.0	0.0	GO:0007538	primary sex determination(GO:0007538)
0.0	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.3	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.2	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.3	GO:0010762	regulation of fibroblast migration(GO:0010762)
0.0	0.8	GO:0061045	negative regulation of wound healing(GO:0061045)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	17.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.4	10.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.3	4.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	7.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	1.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	0.4	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.1	2.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.0	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	2.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	2.8	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	1.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	1.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	3.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	1.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	2.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.7	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.9	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.6	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.3	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	1.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.8	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.6	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.0	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.1	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.4	1.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3	2.7	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.3	1.0	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.3	2.1	GO:0008142	oxysterol binding(GO:0008142)
0.3	3.3	GO:0030274	LIM domain binding(GO:0030274)
0.3	1.1	GO:0035473	lipase binding(GO:0035473)
0.2	0.9	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.2	0.7	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.2	1.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.2	1.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	3.6	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.2	0.6	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2	1.8	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	1.9	GO:0039706	co-receptor binding(GO:0039706)
0.2	0.7	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.2	1.3	GO:0034711	inhibin binding(GO:0034711)
0.2	0.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	1.5	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1	0.7	GO:0050436	microfibril binding(GO:0050436)
0.1	0.9	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.5	GO:0036033	mediator complex binding(GO:0036033)
0.1	1.3	GO:0042731	PH domain binding(GO:0042731)
0.1	0.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.1	1.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	1.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.4	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.1	0.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.8	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1	0.6	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	0.6	GO:0050692	DBD domain binding(GO:0050692)
0.1	1.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.3	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.1	1.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.3	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	1.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	0.3	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.3	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.3	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.4	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.3	GO:0032145	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1	0.3	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.3	GO:0034046	poly(G) binding(GO:0034046)
0.1	0.3	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	0.4	GO:0039552	RIG-I binding(GO:0039552)
0.1	0.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	0.4	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	1.2	GO:0051400	BH domain binding(GO:0051400)
0.1	1.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.2	GO:0005046	KDEL sequence binding(GO:0005046)
0.1	0.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.7	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.2	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.8	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.3	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.3	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.2	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1	0.3	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	2.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.3	GO:0052847	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0	0.3	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.4	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.8	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0	0.1	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.1	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.5	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.8	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.2	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.0	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.7	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.3	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.1	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0	0.6	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0	1.9	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.4	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.8	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0004324	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0	0.6	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.3	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.3	GO:1990380	Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.4	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.2	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.0	0.2	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0	0.2	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0043199	sulfate binding(GO:0043199)
0.0	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0097677	STAT family protein binding(GO:0097677)
0.0	0.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.9	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.5	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	0.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.2	GO:0048185	activin binding(GO:0048185)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.3	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.5	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.2	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	1.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.4	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.2	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.1	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.0	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.1	GO:0000988	transcription factor activity, protein binding(GO:0000988)
0.0	0.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.9	GO:0016209	antioxidant activity(GO:0016209)
0.0	0.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.7	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.2	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.0	1.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.3	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	1.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0	0.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.4	GO:0004888	transmembrane signaling receptor activity(GO:0004888)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.6	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	4.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	4.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	12.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	6.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	5.3	NABA COLLAGENS	Genes encoding collagen proteins
0.1	6.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	2.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	2.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	3.8	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	5.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	0.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	19.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	3.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	4.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	10.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	2.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.7	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	1.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	0.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.9	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	3.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.0	3.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.9	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	1.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	2.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	1.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.7	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	2.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	3.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.3	PID BMP PATHWAY	BMP receptor signaling
0.0	1.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	1.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	1.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	2.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.9	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.2	ST ADRENERGIC	Adrenergic Pathway
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.6	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.8	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	2.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	1.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	2.8	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	3.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.8	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	1.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	3.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	2.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.6	PID ILK PATHWAY	Integrin-linked kinase signaling

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
2.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.6	REACTOME G1 PHASE	Genes involved in G1 Phase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	3.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	3.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	4.7	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	3.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	2.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	2.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	0.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.6	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	1.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	3.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	7.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	4.8	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	1.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.8	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.7	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	1.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	3.8	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	5.7	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	4.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.5	PID REELIN PATHWAY	Reelin signaling pathway
0.0	1.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	5.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	1.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.6	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.9	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.5	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.4	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.5	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	3.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	3.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.0	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.9	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.6	PID CDC42 PATHWAY	CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	1.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.8	11.3	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.5	2.9	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.4	23.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3	12.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3	6.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.3	2.8	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3	6.9	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.3	10.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.3	0.8	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.2	5.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	2.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	3.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2	2.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.2	2.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.2	3.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	1.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2	2.8	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.2	1.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.2	4.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	1.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	4.4	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	1.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	2.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	2.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	2.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	3.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	2.6	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	6.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	3.3	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	7.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.0	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1	3.8	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	1.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	1.4	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.5	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1	2.9	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	1.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	2.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	2.0	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.1	1.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.7	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	12.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	2.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	5.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	6.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	3.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	1.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	0.8	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.9	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.1	0.8	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	2.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	1.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.0	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	0.8	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	1.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	0.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.1	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.9	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.9	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	3.5	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	2.4	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.9	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	3.6	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.3	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.4	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.5	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.6	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.6	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.9	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	2.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	2.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.6	PID MYC PATHWAY	C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	1.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	1.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	2.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	0.9	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.1	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	2.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	3.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	1.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.6	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	2.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	1.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	3.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	15.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	3.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	2.4	PID BMP PATHWAY	BMP receptor signaling
0.0	2.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.5	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	3.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	8.4	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5	11.6	GO:0017166	vinculin binding(GO:0017166)
0.3	8.0	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	1.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3	2.3	GO:0048408	epidermal growth factor binding(GO:0048408)
0.3	4.4	GO:0045499	chemorepellent activity(GO:0045499)
0.3	2.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.2	2.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.2	1.7	GO:0005347	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.2	1.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2	0.5	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.2	1.0	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2	1.4	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	3.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.9	GO:0001515	opioid peptide activity(GO:0001515)
0.1	2.3	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.5	GO:0052833	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.3	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.9	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	3.6	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.1	0.3	GO:0099609	microtubule lateral binding(GO:0099609)
0.1	0.4	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1	0.5	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	1.2	GO:0031402	sodium ion binding(GO:0031402)
0.0	1.2	GO:0071949	FAD binding(GO:0071949)
0.0	0.4	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.4	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.2	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	1.1	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.6	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.2	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	1.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.4	GO:0070628	proteasome binding(GO:0070628)
0.0	6.1	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.5	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0	0.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	1.0	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.7	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	0.0	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	2.9	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.2	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.3	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	3.1	GO:0008017	microtubule binding(GO:0008017)
0.0	0.6	GO:0030971	receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.5	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
4.8	PID IL2 1PATHWAY	IL2-mediated signaling events
0.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.4	PID IL1 PATHWAY	IL1-mediated signaling events
1.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	PID MYC PATHWAY	C-MYC pathway
0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
1.2	PID ARF6 PATHWAY	Arf6 signaling events
1.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.6	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.9	PID AURORA B PATHWAY	Aurora B signaling
0.5	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
1.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
2.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4	PID INSULIN PATHWAY	Insulin Pathway
0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.5	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.9	2.8	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.8	2.5	GO:0048627	myoblast development(GO:0048627)
0.5	2.5	GO:0003164	His-Purkinje system development(GO:0003164)
0.5	1.4	GO:1990108	protein linear deubiquitination(GO:1990108)
0.4	1.3	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.4	2.6	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.3	0.6	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.3	0.8	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2	0.2	GO:2000291	myoblast proliferation(GO:0051450) regulation of myoblast proliferation(GO:2000291)
0.2	0.7	GO:1903348	cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.2	0.7	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.2	0.7	GO:0070631	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2	1.9	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2	0.8	GO:0002545	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.2	0.7	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2	1.8	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2	0.4	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.2	0.5	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.2	0.5	GO:1902534	single-organism membrane invagination(GO:1902534)
0.2	0.8	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.2	0.2	GO:1903525	regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.2	4.9	GO:0007398	ectoderm development(GO:0007398)
0.2	0.5	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2	0.6	GO:0042335	cuticle development(GO:0042335)
0.1	0.7	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.1	0.1	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1	0.4	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.4	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1	0.6	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.1	0.4	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1	0.6	GO:0061143	alveolar primary septum development(GO:0061143)
0.1	0.3	GO:0006939	smooth muscle contraction(GO:0006939)
0.1	0.6	GO:2001076	regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1	0.8	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405)
0.1	0.4	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1	0.3	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1	0.3	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.1	0.3	GO:0006258	UDP-glucose catabolic process(GO:0006258)
0.1	0.3	GO:0071109	superior temporal gyrus development(GO:0071109)
0.1	0.3	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1	0.7	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	0.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	1.5	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.8	GO:0006477	protein sulfation(GO:0006477)
0.1	0.6	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.1	0.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.3	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.2	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1	0.4	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.1	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.2	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.1	0.2	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.1	0.2	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.6	GO:1903912	negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1	0.2	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1	0.2	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.1	0.4	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	7.1	GO:0070268	cornification(GO:0070268)
0.1	0.2	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1	0.8	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.2	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1	0.2	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.1	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	1.0	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.1	0.2	GO:0006106	fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) L-kynurenine metabolic process(GO:0097052)
0.1	0.2	GO:0071895	odontoblast differentiation(GO:0071895)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714)
0.1	0.5	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.7	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	1.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.3	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	0.3	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1	0.2	GO:1902990	leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1	2.8	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1	0.1	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.1	0.9	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.4	GO:0007506	gonadal mesoderm development(GO:0007506)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0	0.5	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.2	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.8	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.4	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.2	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.4	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.5	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0099553	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0	0.5	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.6	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.3	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.7	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.4	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0036018	cellular response to erythropoietin(GO:0036018)
0.0	0.1	GO:0019230	proprioception(GO:0019230)
0.0	0.2	GO:0090649	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0	0.4	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	2.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.0	0.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.3	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.4	GO:0015884	folic acid transport(GO:0015884)
0.0	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0014056	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056)
0.0	0.1	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0	0.2	GO:0051935	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0	0.4	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.1	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.0	0.2	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.4	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.1	GO:0034971	regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971)
0.0	0.2	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.2	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055) protein localization to nucleolus(GO:1902570)
0.0	0.3	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.2	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:2000973	midbrain morphogenesis(GO:1904693) regulation of pro-B cell differentiation(GO:2000973)
0.0	0.1	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0	0.1	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0	0.2	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.0	0.9	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.1	GO:0071233	cellular response to leucine(GO:0071233)
0.0	0.1	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:1990502	dense core granule maturation(GO:1990502)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.4	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.3	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.0	0.3	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.1	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.2	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.4	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.0	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0	0.1	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	1.0	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.3	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0015672	monovalent inorganic cation transport(GO:0015672)
0.0	0.2	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.5	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.1	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.2	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.2	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	1.2	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.0	0.2	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	1.0	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0	1.8	GO:0006023	aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.5	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	2.7	GO:0043542	endothelial cell migration(GO:0043542)
0.0	0.3	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	1.0	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	1.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
0.0	0.3	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.4	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.0	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:0072553	terminal button organization(GO:0072553)
0.0	0.5	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.3	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.2	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6	2.4	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.6	1.8	GO:0070699	type II activin receptor binding(GO:0070699)
0.3	3.5	GO:0042301	phosphate ion binding(GO:0042301)
0.3	2.0	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	1.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.3	1.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2	1.1	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.2	0.9	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	1.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.7	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	1.5	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.3	GO:0004947	bradykinin receptor activity(GO:0004947)
0.1	8.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.3	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	1.0	GO:0051787	misfolded protein binding(GO:0051787)
0.0	1.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	3.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.5	GO:0005522	profilin binding(GO:0005522)
0.0	0.6	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	5.9	GO:0005543	phospholipid binding(GO:0005543)
0.0	0.7	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.5	GO:0019894	kinesin binding(GO:0019894)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	3.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	2.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.8	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	2.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	7.1	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	1.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	1.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	5.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.2	PID ENDOTHELIN PATHWAY	Endothelins
0.0	1.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.7	PID MYC PATHWAY	C-MYC pathway
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.8	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.5	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.6	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.5	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.2	20.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.2	30.0	PID E2F PATHWAY	E2F transcription factor network
0.2	5.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	3.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	12.6	PID AURORA B PATHWAY	Aurora B signaling
0.2	4.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	6.9	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	1.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	8.3	PID PLK1 PATHWAY	PLK1 signaling events
0.1	2.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	0.7	PID MYC PATHWAY	C-MYC pathway
0.1	6.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	8.8	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	2.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	9.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	2.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	2.6	PID ATM PATHWAY	ATM pathway
0.1	1.7	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	6.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	2.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	7.1	PID NOTCH PATHWAY	Notch signaling pathway
0.1	0.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	0.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	1.8	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	2.2	PID AURORA A PATHWAY	Aurora A signaling
0.1	2.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	1.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	2.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	1.8	PID BARD1 PATHWAY	BARD1 signaling events
0.1	1.9	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	0.7	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	3.5	PID IFNG PATHWAY	IFN-gamma pathway
0.1	6.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	2.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	0.7	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	2.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	0.7	PID ALK1 PATHWAY	ALK1 signaling events
0.1	4.9	PID P73PATHWAY	p73 transcription factor network
0.1	1.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	2.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	2.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	2.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	3.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	4.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	3.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	0.9	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	4.1	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.3	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.5	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	3.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.6	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.9	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.6	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	1.6	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.5	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.2	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.6	2.3	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5	1.5	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4	1.2	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.3	0.8	GO:0021592	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.2	0.9	GO:0044861	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.2	0.6	GO:0061055	myotome development(GO:0061055)
0.2	1.8	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.1	0.5	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1	0.5	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.1	1.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.4	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.1	0.3	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.1	0.4	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	2.9	GO:0060325	face morphogenesis(GO:0060325)
0.1	3.9	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.2	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.4	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.1	0.8	GO:1905146	protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) lysosomal protein catabolic process(GO:1905146)
0.1	0.8	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.9	GO:0051546	keratinocyte migration(GO:0051546)
0.1	0.2	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.0	0.4	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	1.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.6	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.3	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.2	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.3	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.2	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.6	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0	0.4	GO:0015825	L-serine transport(GO:0015825)
0.0	0.2	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.3	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0010816	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0	0.2	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.9	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.6	GO:0097503	sialylation(GO:0097503)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.0	0.1	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0	0.3	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.2	GO:0035112	genitalia morphogenesis(GO:0035112)
0.0	0.3	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
0.0	4.1	GO:0007160	cell-matrix adhesion(GO:0007160)
0.0	1.2	GO:0070268	cornification(GO:0070268)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.5	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.0	0.0	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.0	2.2	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0090168	Golgi reassembly(GO:0090168)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	12.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.8	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	5.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	2.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.6	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	4.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	1.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	2.3	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	2.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	1.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.9	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.4	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	3.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
1.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.6	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.9	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	ST GA12 PATHWAY	G alpha 12 Pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.5	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.4	3.5	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.4	1.4	GO:0009386	translational attenuation(GO:0009386)
0.2	0.7	GO:0071314	cellular response to cocaine(GO:0071314)
0.2	1.4	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.2	0.8	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2	1.0	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.1	0.8	GO:0030035	microspike assembly(GO:0030035)
0.1	0.9	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.1	1.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055) negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1	0.3	GO:0043400	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.1	0.5	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1	0.3	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.1	0.6	GO:0048539	bone marrow development(GO:0048539)
0.1	1.3	GO:0000050	urea cycle(GO:0000050)
0.1	1.6	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.1	0.7	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.1	0.3	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1	0.5	GO:0046601	positive regulation of centriole replication(GO:0046601)
0.1	0.3	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	0.5	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.3	GO:1901535	convergent extension involved in axis elongation(GO:0060028) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.1	0.5	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.3	GO:1990519	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1	0.5	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.9	GO:0051096	telomere assembly(GO:0032202) positive regulation of helicase activity(GO:0051096)
0.1	0.3	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1	0.6	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.7	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.3	GO:0043335	protein unfolding(GO:0043335)
0.1	0.6	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1	0.5	GO:1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1	0.4	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.4	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.1	1.2	GO:0031268	pseudopodium organization(GO:0031268)
0.1	0.2	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.1	0.2	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1	0.3	GO:0080009	mRNA methylation(GO:0080009)
0.1	0.2	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.5	GO:0000012	single strand break repair(GO:0000012)
0.1	0.3	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.2	GO:0031860	regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.0	0.7	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.9	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.0	0.3	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.3	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.0	0.8	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0043605	cellular amide catabolic process(GO:0043605)
0.0	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.8	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.5	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.0	0.1	GO:0090309	maintenance of DNA methylation(GO:0010216) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.1	GO:0009183	purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.0	0.2	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.3	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.7	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0072019	carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0	0.6	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.4	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.1	GO:0002879	positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0	0.4	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	1.0	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.1	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.8	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.1	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.0	0.2	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.1	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.0	0.0	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	1.5	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0	0.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.3	GO:0014029	neural crest formation(GO:0014029)
0.0	0.1	GO:0003322	pancreatic A cell development(GO:0003322)
0.0	0.1	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.7	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.5	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.3	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.2	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.6	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.5	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	1.0	GO:0021762	substantia nigra development(GO:0021762)
0.0	0.9	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.3	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.3	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.5	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.6	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	3.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	4.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.8	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	2.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	0.3	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	0.7	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	2.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	1.9	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.8	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.6	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	1.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.5	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.0	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.7	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	1.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.4	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.9	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.4	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	5.5	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.0	4.9	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.8	9.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.7	5.2	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.6	0.6	GO:1903973	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.6	1.7	GO:0072709	cellular response to sorbitol(GO:0072709)
0.6	2.2	GO:2000520	regulation of immunological synapse formation(GO:2000520)
0.5	4.4	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5	2.6	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.5	1.5	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.5	1.9	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5	1.9	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.5	1.9	GO:0072183	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.5	3.2	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.5	1.4	GO:2000173	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.4	0.4	GO:0034340	response to type I interferon(GO:0034340)
0.4	1.3	GO:1902771	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4	0.4	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.4	2.0	GO:0001834	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4	1.1	GO:1904395	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.4	2.3	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.4	3.7	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.4	1.5	GO:0071461	cellular response to redox state(GO:0071461)
0.4	2.5	GO:1990539	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.4	1.1	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.4	2.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.3	2.4	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3	2.8	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.3	1.0	GO:1990523	bone regeneration(GO:1990523)
0.3	0.3	GO:0051255	spindle midzone assembly(GO:0051255)
0.3	1.6	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.3	2.2	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.3	0.9	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.3	0.9	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.3	1.5	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.3	0.6	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.3	0.9	GO:0072275	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3	0.8	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.3	1.1	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3	0.6	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.3	0.6	GO:0002027	regulation of heart rate(GO:0002027)
0.3	2.5	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3	0.8	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3	0.5	GO:0002605	negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.3	0.8	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3	30.7	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.3	1.0	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.2	1.2	GO:0046952	ketone body catabolic process(GO:0046952)
0.2	0.7	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2	1.5	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	0.5	GO:0006550	isoleucine catabolic process(GO:0006550)
0.2	1.2	GO:0014900	muscle hyperplasia(GO:0014900)
0.2	0.9	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.2	0.7	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2	0.2	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.2	1.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2	0.8	GO:0016554	cytidine to uridine editing(GO:0016554)
0.2	0.6	GO:0090291	negative regulation of osteoclast proliferation(GO:0090291)
0.2	1.0	GO:0070269	pyroptosis(GO:0070269)
0.2	0.8	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.2	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.2	0.2	GO:0045636	regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) regulation of pigment cell differentiation(GO:0050932) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.2	2.2	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2	0.2	GO:0035376	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2	0.4	GO:0043132	NAD transport(GO:0043132)
0.2	0.8	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.2	0.2	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.2	0.7	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.2	0.2	GO:1903487	regulation of lactation(GO:1903487)
0.2	0.2	GO:0009118	regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.2	1.5	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2	0.5	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.2	0.4	GO:0070383	DNA cytosine deamination(GO:0070383)
0.2	0.7	GO:0035627	ceramide transport(GO:0035627)
0.2	1.2	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.2	1.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.2	1.2	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2	0.5	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2	0.3	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.2	1.5	GO:0033227	dsRNA transport(GO:0033227)
0.2	1.0	GO:2000334	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2	19.0	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.2	0.5	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586)
0.2	1.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.2	0.5	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.2	0.7	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.2	3.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.2	1.0	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2	1.5	GO:2001300	lipoxin metabolic process(GO:2001300)
0.2	0.2	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2	0.8	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.2	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.2	0.3	GO:0048880	sensory system development(GO:0048880)
0.2	0.3	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.2	0.5	GO:1990922	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2	0.6	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2	1.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.1	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.1	0.4	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.1	0.7	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.1	0.4	GO:0014016	neuroblast differentiation(GO:0014016)
0.1	0.4	GO:0090149	synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.1	0.4	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.1	1.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	0.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	0.4	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.5	GO:0046967	cytosol to ER transport(GO:0046967)
0.1	0.8	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.1	0.4	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	1.3	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.5	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.4	GO:0002580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1	0.1	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.1	0.5	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.1	2.2	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.6	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.5	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.5	GO:0030242	pexophagy(GO:0030242)
0.1	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1	1.0	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1	0.4	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1	0.4	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.1	0.5	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.4	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1	0.4	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.1	0.4	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1	0.2	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.1	0.4	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1	0.5	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.2	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1	0.6	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1	0.3	GO:0046061	dATP catabolic process(GO:0046061)
0.1	0.1	GO:0100009	regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1	0.2	GO:1903413	cellular response to bile acid(GO:1903413)
0.1	1.0	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1	0.6	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	0.1	GO:0009441	glycolate metabolic process(GO:0009441)
0.1	0.3	GO:1904868	telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1	0.1	GO:0006517	protein deglycosylation(GO:0006517)
0.1	0.4	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1	4.9	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.1	GO:0032425	regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.1	1.9	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.3	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1	0.3	GO:0008355	olfactory learning(GO:0008355)
0.1	0.4	GO:1904566	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1	0.1	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1	0.1	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1	0.3	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.1	0.2	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	0.2	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1	0.1	GO:0021761	limbic system development(GO:0021761) hippocampus development(GO:0021766)
0.1	0.7	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.1	0.1	GO:0044266	angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.1	0.6	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.1	0.3	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1	0.1	GO:0072520	seminiferous tubule development(GO:0072520)
0.1	0.4	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1	0.9	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.3	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1	0.7	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.1	0.2	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.1	0.5	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.2	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1	0.3	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.1	0.4	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.5	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.5	GO:0070091	glucagon secretion(GO:0070091)
0.1	0.3	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	0.1	GO:0051715	cytolysis in other organism(GO:0051715)
0.1	0.2	GO:0002727	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1	0.4	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1	0.1	GO:0071353	response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.1	0.4	GO:0046836	glycolipid transport(GO:0046836)
0.1	0.4	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.1	0.4	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.5	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.1	0.1	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.1	0.5	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	1.8	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.1	GO:2000670	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.7	GO:0010818	T cell chemotaxis(GO:0010818)
0.1	0.8	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.1	GO:0044265	cellular macromolecule catabolic process(GO:0044265)
0.1	0.8	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.1	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.1	0.2	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.1	0.3	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	0.2	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1	0.3	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.3	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.1	0.2	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1	0.2	GO:0035723	interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1	0.3	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.3	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.1	0.2	GO:0045345	positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1	0.3	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.4	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.2	GO:1902966	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1	0.9	GO:0045176	apical protein localization(GO:0045176)
0.1	0.6	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.1	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1	0.9	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	1.4	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1	0.4	GO:0072143	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1	0.1	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1	0.4	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	0.3	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.5	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.3	GO:0060455	negative regulation of gastric acid secretion(GO:0060455)
0.1	0.2	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.1	0.3	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1	0.3	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.1	0.5	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.2	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1	0.4	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.1	0.1	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.1	0.8	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.1	0.1	GO:0023016	signal transduction by trans-phosphorylation(GO:0023016)
0.1	0.4	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1	0.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.1	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1	0.2	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.1	0.4	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.1	0.2	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1	0.1	GO:0072019	proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.1	0.1	GO:0032679	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1	0.1	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.1	0.1	GO:1905064	negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1	0.8	GO:0048535	lymph node development(GO:0048535)
0.1	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.7	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.1	0.1	GO:0034250	positive regulation of cellular amide metabolic process(GO:0034250)
0.1	0.3	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	0.4	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.1	0.1	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.1	0.5	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.2	GO:0048254	snoRNA localization(GO:0048254)
0.1	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.1	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.2	GO:2000395	ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1	0.1	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.1	0.2	GO:0051311	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1	1.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.3	GO:0048749	compound eye development(GO:0048749)
0.1	10.5	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1	0.5	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.1	0.9	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	0.5	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.5	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1	0.2	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.1	0.5	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.3	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1	2.5	GO:0033198	response to ATP(GO:0033198)
0.1	0.2	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.2	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1	1.4	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.3	GO:0042908	xenobiotic transport(GO:0042908)
0.1	0.2	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1	0.1	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.1	0.6	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.1	0.2	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
0.1	0.2	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.1	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.2	GO:0006272	leading strand elongation(GO:0006272)
0.1	0.1	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1	0.1	GO:0046874	quinolinate metabolic process(GO:0046874)
0.1	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1	0.1	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
0.1	0.4	GO:0007144	female meiosis I(GO:0007144)
0.1	0.2	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1	0.1	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1	0.2	GO:0038178	complement component C5a signaling pathway(GO:0038178)
0.1	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	0.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.3	GO:0099518	vesicle cytoskeletal trafficking(GO:0099518)
0.1	0.2	GO:0033590	response to cobalamin(GO:0033590)
0.1	0.2	GO:0070638	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) pyridine-containing compound catabolic process(GO:0072526)
0.1	0.2	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.7	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.2	GO:0036336	dendritic cell migration(GO:0036336)
0.1	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.1	1.2	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	0.4	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.1	0.8	GO:1902745	positive regulation of lamellipodium organization(GO:1902745)
0.1	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.0	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.8	GO:0022401	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.1	0.1	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.1	0.4	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	0.5	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	0.8	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.2	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1	0.3	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.1	1.3	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.1	0.2	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.1	0.6	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.1	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.1	0.4	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.6	GO:0051601	exocyst localization(GO:0051601)
0.1	0.3	GO:0035624	receptor transactivation(GO:0035624)
0.1	0.1	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.1	0.1	GO:2001236	regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1	0.3	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.3	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.1	GO:0045006	DNA deamination(GO:0045006)
0.1	0.4	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1	0.2	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1	0.4	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.1	GO:0030431	sleep(GO:0030431)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.6	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
0.1	0.1	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1	0.3	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.1	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.1	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.1	0.3	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	0.2	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1	0.2	GO:0009106	lipoate metabolic process(GO:0009106)
0.1	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.1	0.1	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.1	0.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.1	0.4	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	2.4	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.1	0.1	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.1	0.3	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.1	0.1	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.1	1.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	0.2	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	0.4	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	1.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.6	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.1	0.6	GO:0045794	negative regulation of cell volume(GO:0045794)
0.1	0.2	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.1	0.1	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.1	0.3	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.3	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.1	0.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.9	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.1	0.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.1	0.2	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.1	0.2	GO:1904044	response to aldosterone(GO:1904044)
0.0	0.4	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.0	0.3	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.3	GO:0046782	regulation of viral transcription(GO:0046782)
0.0	0.3	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0048627	myoblast development(GO:0048627)
0.0	0.3	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.2	GO:0050433	regulation of catecholamine secretion(GO:0050433)
0.0	0.2	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.0	GO:0007159	leukocyte cell-cell adhesion(GO:0007159)
0.0	1.5	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0	0.5	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.3	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.3	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.3	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.4	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.0	0.2	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0	0.1	GO:0046601	positive regulation of centriole replication(GO:0046601)
0.0	0.1	GO:1900369	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.0	0.5	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.8	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0007418	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.7	GO:0090168	Golgi reassembly(GO:0090168)
0.0	1.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0071301	transcription factor catabolic process(GO:0036369) cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0	0.1	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.0	0.4	GO:0097341	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0	0.1	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0	0.1	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0	0.1	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0	0.1	GO:0036269	swimming behavior(GO:0036269)
0.0	0.7	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:0061056	sclerotome development(GO:0061056)
0.0	0.1	GO:0046081	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0070640	calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.0	0.0	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.4	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:1901656	glycoside transport(GO:1901656)
0.0	1.2	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.2	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.2	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.0	0.4	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	0.2	GO:0048478	replication fork protection(GO:0048478)
0.0	0.4	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0030073	insulin secretion(GO:0030073)
0.0	0.2	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	0.2	GO:2001076	regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.0	0.3	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:0034163	regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0	0.2	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.3	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.0	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.1	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0	0.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.2	GO:0015811	L-cystine transport(GO:0015811)
0.0	0.7	GO:0007160	cell-matrix adhesion(GO:0007160)
0.0	0.2	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.0	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
0.0	0.1	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.4	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.0	0.2	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.2	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	1.4	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.3	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.0	0.0	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0007060	male meiosis chromosome segregation(GO:0007060)
0.0	0.1	GO:1903410	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0	0.2	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.2	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.5	GO:0044818	mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.1	GO:0097325	melanocyte proliferation(GO:0097325)
0.0	0.2	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.1	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	1.4	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.3	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.2	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0	0.0	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0	0.0	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0044381	glucose import in response to insulin stimulus(GO:0044381)
0.0	0.4	GO:0060737	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.3	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.3	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.3	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.0	0.1	GO:0006597	spermine biosynthetic process(GO:0006597)
0.0	0.2	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.1	GO:0031622	positive regulation of fever generation(GO:0031622) trans-synaptic signalling, modulating synaptic transmission(GO:0099550) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0	0.2	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.1	GO:0060467	negative regulation of fertilization(GO:0060467)
0.0	0.3	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.2	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	0.2	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.3	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.2	GO:1903039	positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0	0.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.2	GO:0072643	interferon-gamma secretion(GO:0072643)
0.0	0.2	GO:0006051	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.1	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.2	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.2	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.2	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	1.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	1.0	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.5	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
0.0	0.0	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.0	0.1	GO:0060920	cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.0	0.8	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0036071	N-glycan fucosylation(GO:0036071)
0.0	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.7	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.0	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.3	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.0	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.1	GO:0032099	negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0	0.2	GO:0006021	inositol biosynthetic process(GO:0006021)
0.0	0.5	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0090301	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0046833	positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.5	GO:0044030	regulation of DNA methylation(GO:0044030)
0.0	0.1	GO:0090656	t-circle formation(GO:0090656)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.2	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.0	GO:0043954	cellular component maintenance(GO:0043954)
0.0	0.1	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.9	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.3	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.3	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.2	GO:0060536	cartilage morphogenesis(GO:0060536)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0031342	negative regulation of cell killing(GO:0031342)
0.0	0.2	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0	0.0	GO:0060993	kidney morphogenesis(GO:0060993)
0.0	0.0	GO:0090487	toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.2	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.4	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.0	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.0	0.2	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.1	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.1	GO:2000484	positive regulation of interleukin-8 secretion(GO:2000484)
0.0	0.2	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.1	GO:0044771	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	0.1	GO:0042297	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.0	0.0	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.0	0.1	GO:0071105	response to interleukin-11(GO:0071105)
0.0	0.5	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.2	GO:1901526	positive regulation of macromitophagy(GO:1901526) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0	0.2	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.3	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0071306	cellular response to vitamin E(GO:0071306)
0.0	3.2	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.0	0.0	GO:0006542	glutamine biosynthetic process(GO:0006542)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.0	0.1	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.1	GO:0021510	spinal cord development(GO:0021510)
0.0	0.1	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.2	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.0	GO:0043931	ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.0	0.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	1.0	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.0	GO:0033206	meiotic cytokinesis(GO:0033206)
0.0	0.1	GO:2000722	nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) mineralocorticoid receptor signaling pathway(GO:0031959) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0	0.1	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0019417	sulfur oxidation(GO:0019417)
0.0	0.1	GO:0060901	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	1.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0031179	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0	0.0	GO:0016068	regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.0	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.1	GO:2001023	regulation of response to drug(GO:2001023)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.2	GO:0099563	modification of synaptic structure(GO:0099563)
0.0	0.2	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.1	GO:0008204	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0	0.1	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.0	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.0	0.1	GO:0071033	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of pre-mRNA at the site of transcription(GO:0071033) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0	0.1	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.1	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.0	0.1	GO:0034121	regulation of toll-like receptor signaling pathway(GO:0034121)
0.0	0.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0006835	dicarboxylic acid transport(GO:0006835)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.0	GO:1905073	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0	0.2	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
0.0	0.1	GO:0060352	cell adhesion molecule production(GO:0060352)
0.0	0.5	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.3	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.1	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0	0.1	GO:0050848	regulation of calcium-mediated signaling(GO:0050848)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0032847	regulation of cellular pH reduction(GO:0032847)
0.0	0.1	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.1	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.0	GO:0045076	regulation of interleukin-2 biosynthetic process(GO:0045076)
0.0	0.1	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.7	GO:0006298	mismatch repair(GO:0006298)
0.0	0.4	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0086018	SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018)
0.0	0.3	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0021764	amygdala development(GO:0021764)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.1	GO:0061739	protein lipidation involved in autophagosome assembly(GO:0061739)
0.0	0.0	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.0	0.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0	0.2	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0	0.1	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.1	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.8	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.1	GO:0006404	RNA import into nucleus(GO:0006404)
0.0	0.2	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.2	GO:0006285	base-excision repair, AP site formation(GO:0006285) depyrimidination(GO:0045008)
0.0	0.4	GO:0043486	histone exchange(GO:0043486)
0.0	0.2	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.2	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0046066	dGDP metabolic process(GO:0046066)
0.0	0.1	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.4	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0071910	determination of liver left/right asymmetry(GO:0071910)
0.0	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.0	GO:0019230	proprioception(GO:0019230)
0.0	0.0	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.3	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.1	GO:0036111	very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0	0.0	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.0	0.1	GO:0046113	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) nucleobase catabolic process(GO:0046113)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.2	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.0	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0	0.1	GO:0009988	cell-cell recognition(GO:0009988)
0.0	0.0	GO:0060938	cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
0.0	0.0	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0	0.9	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.1	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.0	GO:0052251	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.3	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.2	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.1	GO:0014029	neural crest formation(GO:0014029)
0.0	0.1	GO:0014062	regulation of serotonin secretion(GO:0014062)
0.0	0.1	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.2	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.1	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0097052	L-kynurenine metabolic process(GO:0097052)
0.0	0.6	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0048867	stem cell fate determination(GO:0048867)
0.0	0.0	GO:0002644	negative regulation of tolerance induction(GO:0002644)
0.0	1.0	GO:0008542	visual learning(GO:0008542)
0.0	0.1	GO:2000679	positive regulation of transcription regulatory region DNA binding(GO:2000679)
0.0	0.0	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.0	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:0043105	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0	0.1	GO:0035377	transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.2	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.3	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.3	GO:0032945	negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0	0.2	GO:0048538	thymus development(GO:0048538)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.3	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.0	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.2	GO:0071476	cellular hypotonic response(GO:0071476)
0.0	0.0	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176)
0.0	0.2	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.3	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.3	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.1	GO:0035898	parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.0	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928) positive regulation of superoxide anion generation(GO:0032930)
0.0	0.4	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0	1.5	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.1	GO:0007113	endomitotic cell cycle(GO:0007113)
0.0	0.5	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.0	GO:0018283	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0	0.0	GO:0006090	pyruvate metabolic process(GO:0006090)
0.0	0.0	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.0	0.3	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.0	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.0	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.1	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0	0.5	GO:2001259	positive regulation of cation channel activity(GO:2001259)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.2	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.1	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:1904721	regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0	0.1	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.0	0.1	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0007292	female gamete generation(GO:0007292)
0.0	0.1	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	0.0	GO:0043696	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0	0.4	GO:0030728	ovulation(GO:0030728)
0.0	0.3	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.1	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.0	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.3	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	1.7	GO:0007286	spermatid development(GO:0007286)
0.0	0.1	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.0	0.1	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.0	0.3	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.7	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.0	0.0	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.0	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.0	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:1904415	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.2	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.3	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.3	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0	0.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.0	1.6	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.0	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.2	GO:0006188	IMP biosynthetic process(GO:0006188)
0.0	0.1	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.0	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.1	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.4	GO:0006301	postreplication repair(GO:0006301)
0.0	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.0	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0035307	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.1	GO:0032053	ciliary basal body organization(GO:0032053)
0.0	0.0	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.0	GO:0060180	negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050) regulation of female receptivity(GO:0045924) female mating behavior(GO:0060180)
0.0	0.1	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.1	GO:1904528	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.0	0.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.2	GO:0042454	ribonucleoside catabolic process(GO:0042454)
0.0	0.3	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.0	0.0	GO:0046449	creatinine metabolic process(GO:0046449)
0.0	0.1	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.0	0.0	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.0	GO:1990668	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.5	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0042407	cristae formation(GO:0042407)
0.0	0.1	GO:0048263	determination of dorsal identity(GO:0048263)
0.0	0.0	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.1	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.0	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	0.0	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0072017	distal tubule development(GO:0072017)
0.0	0.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.0	GO:0043144	snoRNA processing(GO:0043144)
0.0	0.0	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.2	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0002118	aggressive behavior(GO:0002118)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.2	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	0.0	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.0	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.0	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.1	GO:0044144	modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0	0.0	GO:0035087	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.0	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.0	0.0	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.1	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.0	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.0	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.0	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.2	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.6	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.2	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.3	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.0	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0046203	spermidine catabolic process(GO:0046203)
0.0	0.1	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.0	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.0	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.0	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.2	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.3	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.2	GO:0009083	branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0033341	regulation of collagen binding(GO:0033341)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.3	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.0	GO:1900449	regulation of glutamate receptor signaling pathway(GO:1900449)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	1.2	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.4	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.0	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.0	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.0	GO:0015846	polyamine transport(GO:0015846)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.0	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.2	GO:0009615	response to virus(GO:0009615)
0.0	0.0	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.0	GO:0007272	ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0003018	vascular process in circulatory system(GO:0003018)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.0	GO:0015800	acidic amino acid transport(GO:0015800)
0.0	0.0	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.0	GO:0090183	regulation of kidney development(GO:0090183)
0.0	0.0	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0	0.0	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0	0.1	GO:0000732	strand displacement(GO:0000732)
0.0	0.0	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0	0.0	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.0	GO:0009566	fertilization(GO:0009566)
0.0	0.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.1	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0070255	regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.0	0.1	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.0	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.2	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.0	GO:0009224	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0	0.2	GO:0046839	phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.0	GO:0051754	meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.0	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.1	GO:0010608	posttranscriptional regulation of gene expression(GO:0010608)
0.0	0.0	GO:0048515	spermatid differentiation(GO:0048515)
0.0	0.5	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0030168	platelet activation(GO:0030168)
0.0	0.1	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.1	GO:0006284	base-excision repair(GO:0006284)
0.0	0.4	GO:0070671	response to interleukin-12(GO:0070671)
0.0	0.0	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.1	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.3	GO:0072676	lymphocyte migration(GO:0072676)
0.0	0.1	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
0.0	0.1	GO:0045005	DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0	0.0	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.0	GO:0034113	heterotypic cell-cell adhesion(GO:0034113)
0.0	0.1	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.1	GO:0030091	protein repair(GO:0030091)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.2	2.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	4.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	4.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	4.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	3.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	5.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	2.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	2.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	3.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	2.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.8	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	2.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	1.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.8	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	0.9	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	2.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.8	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	1.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.8	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.7	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	2.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.8	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	1.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	3.6	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	3.4	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.4	7.5	GO:0031089	platelet dense granule lumen(GO:0031089)
0.2	1.0	GO:0036398	TCR signalosome(GO:0036398)
0.2	1.6	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.2	18.8	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2	1.3	GO:0045179	apical cortex(GO:0045179)
0.1	1.0	GO:0044326	dendritic spine neck(GO:0044326)
0.1	1.3	GO:0097255	R2TP complex(GO:0097255)
0.1	1.7	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.7	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	1.5	GO:0045120	pronucleus(GO:0045120)
0.1	8.5	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	0.3	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.5	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	0.6	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.8	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	1.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.5	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.8	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.8	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.5	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.9	GO:0016580	Sin3 complex(GO:0016580)
0.0	1.8	GO:0000786	nucleosome(GO:0000786)
0.0	0.9	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	1.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0044754	autolysosome(GO:0044754)
0.0	3.1	GO:0043204	perikaryon(GO:0043204)
0.0	3.3	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	1.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0043235	receptor complex(GO:0043235)
0.0	0.3	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	2.1	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.3	GO:0070069	cytochrome complex(GO:0070069)
0.0	1.6	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.2	5.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.2	10.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.2	4.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	4.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	2.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	1.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	5.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	11.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.9	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	5.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.3	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
1.6	4.8	GO:0009996	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.2	4.7	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.1	6.6	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.7	6.5	GO:0070141	response to UV-A(GO:0070141)
0.6	2.3	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.6	2.8	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.5	1.5	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5	6.0	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4	5.8	GO:0035372	protein localization to microtubule(GO:0035372)
0.4	0.8	GO:1904833	positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.3	2.2	GO:0070294	renal sodium ion absorption(GO:0070294)
0.3	0.9	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3	1.8	GO:2000334	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3	0.8	GO:0050787	antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) response to antineoplastic agent(GO:0097327)
0.2	0.7	GO:0061055	myotome development(GO:0061055) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2	0.7	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.2	5.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2	10.0	GO:0035329	hippo signaling(GO:0035329)
0.2	0.7	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1	10.2	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	1.0	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1	0.7	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.5	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	1.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	1.0	GO:1904424	regulation of GTP binding(GO:1904424)
0.1	1.4	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.3	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	2.1	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	1.6	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	1.0	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.3	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	3.8	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	0.6	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0	0.2	GO:0042631	cellular response to water deprivation(GO:0042631)
0.0	0.2	GO:0016036	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.0	0.6	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	5.8	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	1.4	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.8	GO:0016574	histone ubiquitination(GO:0016574)
0.0	10.0	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	0.7	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.5	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	3.0	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.1	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	3.8	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.3	GO:0032196	transposition(GO:0032196)
0.0	1.3	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.6	GO:0001885	endothelial cell development(GO:0001885)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	14.6	GO:0061689	tricellular tight junction(GO:0061689)
1.2	3.7	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.0	8.0	GO:0045179	apical cortex(GO:0045179)
1.0	4.9	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.9	4.7	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.9	6.2	GO:0019815	B cell receptor complex(GO:0019815)
0.8	3.1	GO:0001772	immunological synapse(GO:0001772)
0.8	3.1	GO:0070695	FHF complex(GO:0070695)
0.8	6.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.6	20.2	GO:0030057	desmosome(GO:0030057)
0.6	3.0	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.6	1.8	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.6	29.4	GO:0042571	immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.5	1.5	GO:0005960	glycine cleavage complex(GO:0005960)
0.5	2.0	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.5	1.8	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.4	1.3	GO:0042584	chromaffin granule membrane(GO:0042584)
0.4	4.4	GO:0042627	chylomicron(GO:0042627)
0.4	1.9	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.4	2.3	GO:1990357	terminal web(GO:1990357)
0.4	1.1	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3	2.4	GO:0033269	internode region of axon(GO:0033269)
0.3	0.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.3	4.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	1.9	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.3	0.6	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3	4.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.3	0.6	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3	1.6	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.3	1.9	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3	0.8	GO:0031262	Ndc80 complex(GO:0031262)
0.3	0.8	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3	5.3	GO:0042613	MHC class II protein complex(GO:0042613)
0.3	0.5	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.3	1.3	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2	1.7	GO:0097209	epidermal lamellar body(GO:0097209)
0.2	2.1	GO:0016013	syntrophin complex(GO:0016013)
0.2	0.9	GO:0071001	U4/U6 snRNP(GO:0071001)
0.2	2.5	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.2	0.9	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	0.9	GO:0000811	GINS complex(GO:0000811)
0.2	9.9	GO:0045095	keratin filament(GO:0045095)
0.2	2.0	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2	0.6	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.2	0.6	GO:0031417	NatC complex(GO:0031417)
0.2	0.2	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.2	15.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.2	0.8	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.2	2.6	GO:0005577	fibrinogen complex(GO:0005577)
0.2	1.6	GO:0005587	collagen type IV trimer(GO:0005587)
0.2	5.0	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2	1.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.2	3.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.2	3.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.2	0.8	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2	0.2	GO:0033503	HULC complex(GO:0033503)
0.2	4.5	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.2	2.9	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	1.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	2.5	GO:0045120	pronucleus(GO:0045120)
0.2	1.3	GO:0051233	spindle midzone(GO:0051233)
0.2	1.4	GO:0070652	HAUS complex(GO:0070652)
0.2	2.7	GO:0043020	NADPH oxidase complex(GO:0043020)
0.2	1.1	GO:1990635	proximal dendrite(GO:1990635)
0.2	1.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	0.9	GO:0042825	TAP complex(GO:0042825)
0.2	0.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	0.8	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2	1.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	0.9	GO:0008537	proteasome activator complex(GO:0008537)
0.2	0.6	GO:0032420	stereocilium(GO:0032420)
0.2	1.7	GO:0042555	MCM complex(GO:0042555)
0.1	0.6	GO:1990031	pinceau fiber(GO:1990031)
0.1	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	0.4	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	2.8	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	3.4	GO:0034706	sodium channel complex(GO:0034706)
0.1	0.4	GO:0036398	TCR signalosome(GO:0036398)
0.1	1.5	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.1	1.4	GO:0070187	telosome(GO:0070187)
0.1	0.3	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	0.4	GO:0030689	Noc complex(GO:0030689)
0.1	2.4	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.3	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.1	1.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	1.9	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	0.6	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.5	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.5	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.1	0.4	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.1	0.1	GO:0000502	proteasome complex(GO:0000502)
0.1	0.4	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1	0.1	GO:0097228	sperm principal piece(GO:0097228)
0.1	0.7	GO:0030673	axolemma(GO:0030673)
0.1	0.5	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	0.5	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	0.5	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.1	0.6	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	0.1	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	1.2	GO:0005642	annulate lamellae(GO:0005642)
0.1	1.4	GO:0000800	lateral element(GO:0000800)
0.1	1.6	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.3	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.1	0.3	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.2	GO:0035976	AP1 complex(GO:0035976)
0.1	0.3	GO:0002139	stereocilia coupling link(GO:0002139)
0.1	0.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	2.1	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.8	GO:0000322	storage vacuole(GO:0000322)
0.1	0.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.5	GO:0031970	organelle envelope lumen(GO:0031970)
0.1	0.9	GO:0005833	hemoglobin complex(GO:0005833)
0.1	1.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	0.5	GO:0034457	Mpp10 complex(GO:0034457)
0.1	0.6	GO:0070470	plasma membrane respiratory chain(GO:0070470)
0.1	1.0	GO:0097440	apical dendrite(GO:0097440)
0.1	0.8	GO:0005610	laminin-5 complex(GO:0005610)
0.1	1.5	GO:0032433	filopodium tip(GO:0032433)
0.1	5.9	GO:0015030	Cajal body(GO:0015030)
0.1	5.3	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	0.5	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.4	GO:0030314	junctional membrane complex(GO:0030314)
0.1	1.7	GO:0032156	septin cytoskeleton(GO:0032156)
0.1	1.4	GO:0001741	XY body(GO:0001741)
0.1	2.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	2.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	4.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	0.5	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	1.5	GO:0045277	respiratory chain complex IV(GO:0045277)
0.1	5.7	GO:0031526	brush border membrane(GO:0031526)
0.1	0.3	GO:0098559	cytoplasmic side of endosome membrane(GO:0010009) cytoplasmic side of early endosome membrane(GO:0098559)
0.1	2.4	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.1	GO:0005801	cis-Golgi network(GO:0005801)
0.1	1.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	1.1	GO:0097433	dense body(GO:0097433)
0.1	0.5	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	11.4	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.1	0.3	GO:0034455	t-UTP complex(GO:0034455)
0.1	1.5	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1	0.2	GO:0044423	virion(GO:0019012) virion part(GO:0044423)
0.1	0.7	GO:0005827	polar microtubule(GO:0005827)
0.1	0.2	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.1	0.5	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1	0.6	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	1.6	GO:0044447	axoneme part(GO:0044447)
0.1	0.4	GO:0005899	insulin receptor complex(GO:0005899)
0.1	4.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	1.2	GO:0030686	90S preribosome(GO:0030686)
0.1	0.4	GO:0030905	retromer, tubulation complex(GO:0030905)
0.1	0.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.1	0.3	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.2	GO:0031523	Myb complex(GO:0031523)
0.1	0.2	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1	0.8	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	1.6	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.4	GO:0032021	NELF complex(GO:0032021)
0.1	0.4	GO:0033391	chromatoid body(GO:0033391)
0.1	0.6	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1	1.0	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.5	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1	2.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	0.2	GO:0001652	granular component(GO:0001652)
0.1	0.4	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.7	GO:0042587	glycogen granule(GO:0042587)
0.1	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	0.3	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.4	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.1	GO:0031967	organelle envelope(GO:0031967) envelope(GO:0031975)
0.1	0.3	GO:0043293	apoptosome(GO:0043293)
0.1	0.3	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.1	2.2	GO:1902710	GABA receptor complex(GO:1902710)
0.1	0.3	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0097452	GAIT complex(GO:0097452)
0.1	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.7	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	2.4	GO:0005902	microvillus(GO:0005902)
0.1	0.3	GO:0032280	symmetric synapse(GO:0032280)
0.1	0.2	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.6	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.1	1.0	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	19.4	GO:0031965	nuclear membrane(GO:0031965)
0.1	2.8	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	0.4	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.8	GO:0031089	platelet dense granule lumen(GO:0031089)
0.1	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	5.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	0.3	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	0.4	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.2	GO:0005873	plus-end kinesin complex(GO:0005873)
0.1	0.6	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.1	0.5	GO:0000796	condensin complex(GO:0000796)
0.1	1.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	2.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	1.0	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	1.2	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0032449	CBM complex(GO:0032449)
0.0	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0031201	SNARE complex(GO:0031201)
0.0	0.4	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.1	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	1.7	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.4	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.2	GO:1990393	3M complex(GO:1990393)
0.0	1.6	GO:0031672	A band(GO:0031672)
0.0	0.3	GO:0005686	U2 snRNP(GO:0005686)
0.0	3.1	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.0	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	6.4	GO:0000922	spindle pole(GO:0000922)
0.0	7.6	GO:0031968	organelle outer membrane(GO:0031968)
0.0	2.2	GO:0005871	kinesin complex(GO:0005871)
0.0	2.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.2	GO:0005657	replication fork(GO:0005657)
0.0	0.7	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.4	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	1.0	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.7	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	1.9	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	1.4	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.3	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.4	GO:0097486	multivesicular body lumen(GO:0097486)
0.0	0.8	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	1.8	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0043203	axon hillock(GO:0043203)
0.0	0.1	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.2	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.1	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	1.3	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0044305	calyx of Held(GO:0044305)
0.0	0.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	3.5	GO:0016605	PML body(GO:0016605)
0.0	1.7	GO:0044815	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0	0.0	GO:0060201	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.4	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	0.2	GO:0097361	CIA complex(GO:0097361)
0.0	0.8	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.2	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.2	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0	0.2	GO:1904115	cell projection cytoplasm(GO:0032838) axon cytoplasm(GO:1904115)
0.0	0.4	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.2	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0	0.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.8	GO:0044454	nuclear chromosome part(GO:0044454)
0.0	0.1	GO:0019867	outer membrane(GO:0019867)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	2.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.6	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	0.2	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.5	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.1	GO:0032302	MutSbeta complex(GO:0032302)
0.0	0.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	1.1	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	2.0	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	3.5	GO:0072562	blood microparticle(GO:0072562)
0.0	0.5	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.2	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	0.5	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.5	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	1.8	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	2.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.2	GO:0098839	postsynaptic density membrane(GO:0098839)
0.0	0.1	GO:0060198	clathrin-sculpted vesicle(GO:0060198)
0.0	0.3	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.0	GO:0033565	ESCRT-0 complex(GO:0033565)
0.0	0.1	GO:1990745	EARP complex(GO:1990745)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.0	GO:0035838	growing cell tip(GO:0035838) cell tip(GO:0051286)
0.0	1.4	GO:0043204	perikaryon(GO:0043204)
0.0	0.2	GO:0000439	core TFIIH complex(GO:0000439)
0.0	7.1	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.0	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.2	GO:0044754	autolysosome(GO:0044754)
0.0	1.5	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0035370	UBC13-UEV1A complex(GO:0035370)
0.0	0.1	GO:0034657	GID complex(GO:0034657)
0.0	14.0	GO:0005730	nucleolus(GO:0005730)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	1.0	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.6	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.0	1.6	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.0	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.4	GO:0001533	cornified envelope(GO:0001533)
0.0	0.0	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.4	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.3	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.7	GO:0005814	centriole(GO:0005814)
0.0	0.0	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.0	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.0	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	1.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.8	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	3.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	0.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.8	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.9	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.5	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	4.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	2.6	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.6	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.8	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	2.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	2.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	3.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.4	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	1.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	2.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.7	REACTOME KINESINS	Genes involved in Kinesins
0.1	3.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.9	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	3.0	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	1.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	1.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.1	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	1.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	2.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	1.5	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0	0.9	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	1.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	2.0	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.0	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.7	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	3.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	1.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	7.7	GO:0030369	ICAM-3 receptor activity(GO:0030369)
1.0	6.0	GO:0042610	CD8 receptor binding(GO:0042610)
1.0	3.9	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.8	5.5	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6	1.7	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.5	1.9	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.4	7.8	GO:0005522	profilin binding(GO:0005522)
0.4	0.4	GO:0035325	Toll-like receptor binding(GO:0035325)
0.4	1.3	GO:0032767	copper-dependent protein binding(GO:0032767)
0.4	1.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.4	0.4	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.3	3.7	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.3	1.0	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.3	1.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3	1.4	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3	0.8	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.3	0.8	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.3	2.0	GO:1990405	protein antigen binding(GO:1990405)
0.2	4.1	GO:0003680	AT DNA binding(GO:0003680)
0.2	0.8	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2	0.4	GO:0032427	GBD domain binding(GO:0032427)
0.2	3.5	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	1.2	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.2	0.6	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.2	5.7	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.2	1.2	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2	3.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.2	0.2	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
0.2	3.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.2	2.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.2	0.5	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2	0.5	GO:0015235	cobalamin transporter activity(GO:0015235)
0.2	0.8	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1	3.7	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	2.3	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	4.3	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	3.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	1.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.7	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	1.0	GO:0005534	galactose binding(GO:0005534)
0.1	1.7	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	1.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	1.1	GO:0043426	MRF binding(GO:0043426)
0.1	1.0	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	0.4	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.1	0.8	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1	5.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.5	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.6	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1	0.6	GO:0070566	adenylyltransferase activity(GO:0070566)
0.1	1.0	GO:0042731	PH domain binding(GO:0042731)
0.1	0.7	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.1	0.6	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.4	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	2.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.9	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.4	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.6	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	0.4	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	0.3	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.9	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.3	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.3	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.3	GO:0097677	STAT family protein binding(GO:0097677)
0.1	0.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.4	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	1.6	GO:0051400	BH domain binding(GO:0051400)
0.1	1.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	1.1	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.4	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	0.8	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.1	0.2	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.4	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.1	1.1	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	1.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	0.8	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.3	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.1	0.3	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.1	1.7	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1	0.8	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.3	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	0.6	GO:0089720	caspase binding(GO:0089720)
0.1	2.7	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.4	GO:0070513	death domain binding(GO:0070513)
0.1	1.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	2.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.4	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.5	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.2	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1	0.4	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.3	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	0.3	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.9	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.2	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0	0.2	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0	0.4	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	1.0	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	1.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.0	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.2	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	0.9	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.1	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.5	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.0	0.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	1.6	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	1.2	GO:0043236	laminin binding(GO:0043236)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	1.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.8	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.8	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.3	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.9	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.6	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.4	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	3.9	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.5	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	1.1	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.4	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.8	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.3	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.5	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.8	GO:0004180	carboxypeptidase activity(GO:0004180)
0.0	0.1	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.4	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	2.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.7	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.0	0.2	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	1.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	1.8	GO:0003682	chromatin binding(GO:0003682)
0.0	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.4	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	2.3	GO:0005178	integrin binding(GO:0005178)
0.0	0.4	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.4	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	1.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.2	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.7	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	1.4	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	2.7	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.1	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0	0.8	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.0	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.4	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	0.3	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.4	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	15.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3	4.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	3.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	9.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	0.9	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	4.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	3.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	3.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.9	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	2.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	3.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	4.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	2.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	10.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	0.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	3.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	2.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.0	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.6	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	1.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:0007412	axon target recognition(GO:0007412)
0.8	3.4	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.8	3.9	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.7	4.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.6	3.9	GO:0089700	protein kinase D signaling(GO:0089700)
0.5	1.6	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.5	2.0	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4	1.7	GO:1902612	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.4	1.3	GO:1905066	arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4	1.2	GO:2000777	positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.3	1.0	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3	1.3	GO:0021564	vagus nerve development(GO:0021564)
0.3	1.6	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3	1.6	GO:1902378	vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.3	1.2	GO:0071492	cellular response to UV-A(GO:0071492)
0.3	1.5	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.3	1.5	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.3	2.4	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.3	2.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2	1.5	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	0.7	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2	1.4	GO:0022614	membrane to membrane docking(GO:0022614)
0.2	0.9	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2	1.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.2	1.9	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.2	2.7	GO:0032060	bleb assembly(GO:0032060)
0.2	0.6	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.2	0.5	GO:0060127	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2	1.1	GO:0052565	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.2	1.6	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.2	2.4	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2	0.8	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.5	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.1	0.7	GO:0010269	response to selenium ion(GO:0010269)
0.1	1.3	GO:0010265	SCF complex assembly(GO:0010265)
0.1	1.3	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.8	GO:0007386	compartment pattern specification(GO:0007386)
0.1	1.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	1.4	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.2	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.1	0.5	GO:0006382	adenosine to inosine editing(GO:0006382)
0.1	0.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.6	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256)
0.1	0.4	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	0.3	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.9	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.1	0.7	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1	0.1	GO:0032752	regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
0.1	1.3	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.7	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	2.7	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	1.8	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.7	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	5.9	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.5	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.1	4.3	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.1	1.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	1.2	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1	0.8	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.4	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.5	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.1	0.5	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	1.1	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1	0.4	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.2	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0	0.5	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	1.6	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.2	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.0	0.8	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	1.0	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.3	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.0	0.2	GO:0046785	microtubule polymerization(GO:0046785)
0.0	0.4	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0	0.3	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.4	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:1904647	response to rotenone(GO:1904647)
0.0	0.0	GO:2000229	pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0	0.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.1	GO:0060796	regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0	0.1	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087)
0.0	0.2	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	1.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.3	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.4	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0	0.1	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.1	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.3	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.7	GO:0097503	sialylation(GO:0097503)
0.0	0.2	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.9	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.6	GO:0030728	ovulation(GO:0030728)
0.0	0.8	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.2	GO:0060346	bone trabecula formation(GO:0060346)
0.0	0.9	GO:0008347	glial cell migration(GO:0008347)
0.0	0.5	GO:0010842	retina layer formation(GO:0010842)
0.0	1.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	1.5	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	1.8	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.4	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.5	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.3	GO:0060004	reflex(GO:0060004)
0.0	0.8	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0014040	positive regulation of Schwann cell differentiation(GO:0014040) cellular response to peptidoglycan(GO:0071224)
0.0	0.1	GO:0071105	response to interleukin-11(GO:0071105)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	1.5	GO:0042476	odontogenesis(GO:0042476)
0.0	0.1	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.4	GO:0050821	protein stabilization(GO:0050821)
0.0	0.2	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.7	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.7	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.6	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2	8.2	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.2	4.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	1.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.9	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	1.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	7.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	3.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	1.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	4.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.9	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	1.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	1.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.7	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.8	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.7	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	1.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.7	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	3.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	2.9	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	1.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	1.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	3.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.9	REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION	Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.1	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	1.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	3.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.8	3.4	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.8	3.3	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.8	3.9	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6	5.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5	1.5	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.5	2.5	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.4	1.8	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.4	1.8	GO:0005046	KDEL sequence binding(GO:0005046)
0.4	1.3	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4	2.3	GO:0003796	lysozyme activity(GO:0003796)
0.3	0.6	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.2	0.7	GO:0052895	norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.2	0.7	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2	3.0	GO:0038132	neuregulin binding(GO:0038132)
0.2	3.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.2	4.1	GO:0051787	misfolded protein binding(GO:0051787)
0.2	3.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.2	1.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.2	1.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	0.5	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.2	0.9	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1	0.7	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1	0.4	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	1.3	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.4	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	1.9	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	1.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	1.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	0.3	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1	0.6	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	5.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.6	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	1.9	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.8	GO:0032190	acrosin binding(GO:0032190)
0.1	0.3	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.8	GO:0046790	virion binding(GO:0046790)
0.1	0.4	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	0.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.7	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.3	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.1	1.3	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	1.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.6	GO:0036310	annealing helicase activity(GO:0036310)
0.1	1.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.4	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	1.5	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.7	GO:0045159	myosin II binding(GO:0045159)
0.1	1.7	GO:0030371	translation repressor activity(GO:0030371)
0.1	5.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.8	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.6	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	1.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.8	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.1	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.7	GO:0001968	fibronectin binding(GO:0001968)
0.0	1.3	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	0.8	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	1.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	4.9	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.3	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	1.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	2.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	2.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.0	1.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.3	GO:0070628	proteasome binding(GO:0070628)
0.0	0.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.2	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.3	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.7	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.4	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.9	GO:0005507	copper ion binding(GO:0005507)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.9	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.8	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	1.1	GO:0016209	antioxidant activity(GO:0016209)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.9	GO:0031625	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)
0.0	1.6	GO:0020037	heme binding(GO:0020037)
0.0	0.0	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	0.1	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	0.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	0.4	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	4.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.8	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	3.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	2.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	2.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.9	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	3.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	2.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	5.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	4.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	0.6	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.1	1.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	1.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	1.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	2.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	4.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	1.8	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	3.0	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.5	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
1.1	4.3	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.5	3.3	GO:1902560	GMP reductase complex(GO:1902560)
0.3	1.6	GO:1990393	3M complex(GO:1990393)
0.3	0.9	GO:0005607	laminin-2 complex(GO:0005607)
0.2	0.7	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.2	0.6	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2	0.8	GO:0070985	TFIIK complex(GO:0070985)
0.2	0.6	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.2	0.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	1.1	GO:0061689	tricellular tight junction(GO:0061689)
0.1	0.4	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	1.6	GO:0097443	sorting endosome(GO:0097443)
0.1	0.4	GO:0034685	integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.1	1.7	GO:0043203	axon hillock(GO:0043203)
0.1	0.4	GO:0061673	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.1	1.4	GO:0005883	neurofilament(GO:0005883)
0.1	0.4	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	1.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.4	GO:0071020	post-spliceosomal complex(GO:0071020)
0.1	0.5	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.7	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	0.3	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.4	GO:0032044	DSIF complex(GO:0032044)
0.1	0.5	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.1	0.4	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.5	GO:0071797	LUBAC complex(GO:0071797)
0.1	0.7	GO:0097427	microtubule bundle(GO:0097427)
0.1	0.4	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	0.4	GO:1990745	EARP complex(GO:1990745)
0.1	0.6	GO:0071817	MMXD complex(GO:0071817)
0.1	0.6	GO:0016589	NURF complex(GO:0016589)
0.1	1.4	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.1	0.5	GO:0070435	Shc-EGFR complex(GO:0070435)
0.1	1.0	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.4	GO:0097422	tubular endosome(GO:0097422)
0.1	0.4	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.1	0.3	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.7	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0071159	NF-kappaB complex(GO:0071159)
0.1	0.6	GO:0031209	SCAR complex(GO:0031209)
0.1	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.3	GO:1990357	terminal web(GO:1990357)
0.1	0.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	0.3	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.4	GO:0000813	ESCRT I complex(GO:0000813)
0.1	0.2	GO:0030689	Noc complex(GO:0030689)
0.1	0.3	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.7	GO:0030478	actin cap(GO:0030478)
0.0	0.1	GO:0019034	viral replication complex(GO:0019034)
0.0	0.8	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.2	GO:1990037	Lewy body core(GO:1990037)
0.0	0.4	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	1.9	GO:0031941	filamentous actin(GO:0031941)
0.0	0.3	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0	0.3	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	1.2	GO:0030057	desmosome(GO:0030057)
0.0	0.4	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.3	GO:0061574	ASAP complex(GO:0061574)
0.0	0.4	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.3	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.5	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.4	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.4	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.4	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.6	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.9	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.0	0.1	GO:1902636	kinociliary basal body(GO:1902636)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.4	GO:0030914	STAGA complex(GO:0030914)
0.0	3.1	GO:0005901	caveola(GO:0005901)
0.0	0.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0070938	dystroglycan complex(GO:0016011) contractile ring(GO:0070938)
0.0	0.2	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	2.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.6	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726) pre-snoRNP complex(GO:0070761)
0.0	0.3	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.3	GO:0000346	transcription export complex(GO:0000346)
0.0	0.3	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.8	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	1.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.6	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.1	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.0	0.6	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	0.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.3	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.4	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.8	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.1	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	1.0	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	2.1	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.3	GO:0031105	septin complex(GO:0031105)
0.0	0.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.2	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	1.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.8	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.0	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0035061	Smc5-Smc6 complex(GO:0030915) interchromatin granule(GO:0035061)
0.0	0.8	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	1.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.3	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0097346	INO80-type complex(GO:0097346)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.3	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.0	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.0	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.2	GO:0035371	microtubule plus-end(GO:0035371)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	10.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	4.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	3.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	10.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	5.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	1.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	2.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.8	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	2.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.9	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.8	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.5	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.7	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	3.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.7	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	3.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	4.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	10.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	6.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	5.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	2.0	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	2.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	2.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	4.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	9.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	3.7	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	2.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	6.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	2.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	0.9	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	3.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.0	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	1.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.6	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.1	1.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	2.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	5.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	1.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	1.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	2.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	5.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	2.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	1.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	0.8	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	1.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	1.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	4.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	2.4	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.9	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	1.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	2.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.8	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.8	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.6	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.4	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	1.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	2.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	4.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	2.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	4.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	1.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	4.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.3	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.8	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	2.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.3	0.8	GO:0034680	integrin alpha10-beta1 complex(GO:0034680)
0.2	0.7	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.2	1.4	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.2	4.6	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	0.5	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	1.6	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	2.0	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	1.0	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.2	0.2	GO:0072563	endothelial microparticle(GO:0072563)
0.1	2.2	GO:0030478	actin cap(GO:0030478)
0.1	0.8	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	0.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.4	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1	0.4	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	1.3	GO:0033270	paranode region of axon(GO:0033270)
0.1	2.3	GO:0032433	filopodium tip(GO:0032433)
0.1	0.9	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	1.3	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	1.6	GO:0042583	chromaffin granule(GO:0042583)
0.1	7.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	2.4	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	0.7	GO:0000813	ESCRT I complex(GO:0000813)
0.1	1.5	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	1.8	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.1	0.9	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.6	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.5	GO:1990812	growth cone filopodium(GO:1990812)
0.1	0.1	GO:0031523	Myb complex(GO:0031523)
0.1	0.6	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	0.2	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.1	0.2	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1	1.2	GO:0097342	ripoptosome(GO:0097342)
0.1	1.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	0.2	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1	0.2	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.1	0.9	GO:0005916	fascia adherens(GO:0005916)
0.1	0.2	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.3	GO:0033263	CORVET complex(GO:0033263)
0.1	0.8	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.4	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:1990423	RZZ complex(GO:1990423)
0.1	0.9	GO:0032059	bleb(GO:0032059)
0.1	1.0	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.2	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.2	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0032302	MutSbeta complex(GO:0032302)
0.0	0.3	GO:1902560	GMP reductase complex(GO:1902560)
0.0	0.1	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	1.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.2	GO:0001940	male pronucleus(GO:0001940)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.6	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	1.0	GO:0042641	actomyosin(GO:0042641)
0.0	0.2	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.5	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.1	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.3	GO:0014802	terminal cisterna(GO:0014802)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.8	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	3.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.0	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0005873	plus-end kinesin complex(GO:0005873)
0.0	0.2	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.3	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.0	0.3	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.5	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	6.9	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.0	0.3	GO:0034464	BBSome(GO:0034464)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	2.0	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.2	GO:0071546	pi-body(GO:0071546)
0.0	1.7	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.7	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	4.7	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0098839	postsynaptic density membrane(GO:0098839)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.1	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.2	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0	0.2	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.5	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.3	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0097224	sperm connecting piece(GO:0097224)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	1.8	GO:0035580	specific granule lumen(GO:0035580)
0.0	1.7	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.3	GO:0036038	MKS complex(GO:0036038)
0.0	1.3	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.3	GO:0005687	U4 snRNP(GO:0005687)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.4	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.3	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.5	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0097447	dendritic tree(GO:0097447)
0.0	0.4	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.1	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0070195	growth hormone receptor complex(GO:0070195)
0.0	0.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	1.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.2	GO:0036452	ESCRT complex(GO:0036452)
0.0	0.3	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.6	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.5	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.5	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	1.0	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.4	GO:0098791	trans-Golgi network(GO:0005802) Golgi subcompartment(GO:0098791)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.0	GO:0097361	CIA complex(GO:0097361)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.4	GO:0097346	INO80-type complex(GO:0097346)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.3	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.0	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0030662	coated vesicle membrane(GO:0030662)
0.0	0.6	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	1.6	GO:0070382	exocytic vesicle(GO:0070382)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.1	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	2.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	2.2	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	0.4	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	0.7	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.3	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
0.1	0.3	GO:0005715	late recombination nodule(GO:0005715)
0.1	0.6	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.4	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.5	GO:0072487	MSL complex(GO:0072487)
0.1	0.2	GO:0031523	Myb complex(GO:0031523)
0.1	0.3	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.1	0.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.5	GO:0005638	lamin filament(GO:0005638)
0.1	0.2	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.0	1.1	GO:0071564	npBAF complex(GO:0071564)
0.0	1.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.4	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.4	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.2	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.0	0.5	GO:0031209	SCAR complex(GO:0031209)
0.0	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.4	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:1990037	Lewy body core(GO:1990037)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.5	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.4	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.6	GO:0042629	mast cell granule(GO:0042629)
0.0	0.5	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0	0.2	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.7	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.4	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.0	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.6	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.7	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.4	GO:0000792	heterochromatin(GO:0000792)
0.0	0.0	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.0	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.0	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.0	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.5	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.3	1.0	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.3	0.8	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2	3.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.2	0.9	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.2	0.6	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	0.8	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.4	GO:0004730	pseudouridylate synthase activity(GO:0004730)
0.1	1.5	GO:0031386	protein tag(GO:0031386)
0.1	0.4	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	2.9	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.7	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.4	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.1	1.9	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.6	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1	2.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.4	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.8	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.4	GO:0016936	galactoside binding(GO:0016936)
0.1	0.3	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	0.3	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.6	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.6	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	1.0	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.1	0.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.3	GO:0033149	FFAT motif binding(GO:0033149)
0.1	1.9	GO:0046961	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.4	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.5	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.3	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.3	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.3	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	1.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	2.4	GO:0030332	cyclin binding(GO:0030332)
0.1	0.2	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.2	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	0.2	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	0.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.2	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1	1.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.2	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.1	1.0	GO:0008603	cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	0.3	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	0.2	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.1	0.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	0.8	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.5	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0	0.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.8	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.2	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.0	0.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.2	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.2	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.3	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.3	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.0	0.2	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	0.2	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.2	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.5	GO:0010857	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0	0.6	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0	0.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.0	2.1	GO:0005507	copper ion binding(GO:0005507)
0.0	0.4	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	1.2	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.3	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	1.9	GO:0019003	GDP binding(GO:0019003)
0.0	0.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.0	0.6	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.4	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.5	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)
0.0	0.4	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.6	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.7	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	1.7	GO:0019905	syntaxin binding(GO:0019905)
0.0	1.2	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.2	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.0	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.0	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.0	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.0	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.4	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.8	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.8	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.3	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0043142	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	1.6	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.0	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.3	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0015250	water channel activity(GO:0015250)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.5	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0003678	DNA helicase activity(GO:0003678)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.3	4.5	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2	2.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	3.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	2.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	3.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.7	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	1.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	2.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.7	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	3.0	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	2.0	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	4.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	1.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	5.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	1.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	0.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.9	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	1.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	1.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	2.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.8	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	2.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.5	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.9	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.3	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	4.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	2.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	2.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	6.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	2.9	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	11.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.9	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	3.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	0.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	6.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	1.8	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.6	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	1.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.9	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	1.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.9	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	1.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	1.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.9	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.6	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.6	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0071953	elastic fiber(GO:0071953)
0.0	0.9	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.7	GO:0030478	actin cap(GO:0030478)
0.0	3.9	GO:0043195	terminal bouton(GO:0043195)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.3	GO:0032982	myosin filament(GO:0032982)
0.0	0.8	GO:0055038	recycling endosome membrane(GO:0055038)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.3	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.9	3.6	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.5	3.3	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.5	2.2	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5	1.6	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.5	1.9	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5	1.4	GO:0021569	rhombomere 3 development(GO:0021569)
0.4	2.0	GO:0070980	biphenyl catabolic process(GO:0070980)
0.4	2.4	GO:0003350	pulmonary myocardium development(GO:0003350)
0.3	3.3	GO:0009414	response to water deprivation(GO:0009414)
0.3	0.8	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.2	3.7	GO:0043589	skin morphogenesis(GO:0043589)
0.2	1.1	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2	1.3	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.2	0.6	GO:0032771	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.2	1.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2	0.9	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2	0.7	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2	1.8	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.2	0.9	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	0.7	GO:1900244	positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.1	0.8	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	1.4	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.1	0.3	GO:0031627	telomeric loop formation(GO:0031627) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1	0.5	GO:2000782	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1	1.7	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.3	GO:1900229	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1	2.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.3	GO:0031337	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1	0.3	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971) fasciculation of sensory neuron axon(GO:0097155)
0.1	0.2	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1	0.2	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1	0.4	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.2	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1	0.6	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.8	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.4	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.1	2.4	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.1	0.2	GO:0033076	isoquinoline alkaloid metabolic process(GO:0033076)
0.1	0.4	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.3	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.5	GO:0015846	polyamine transport(GO:0015846)
0.0	0.2	GO:0072717	cellular response to actinomycin D(GO:0072717)
0.0	0.2	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.4	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.3	GO:2000332	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0	2.7	GO:0035904	aorta development(GO:0035904)
0.0	0.6	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	1.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:0033133	fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.4	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	2.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.2	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	2.4	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	4.1	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.1	GO:1904616	regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0	0.5	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.0	0.3	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.4	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.3	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	1.2	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.7	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.0	0.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	2.2	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.3	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.3	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	1.4	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:1903960	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.0	0.3	GO:0030220	platelet formation(GO:0030220)
0.0	0.2	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.2	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.4	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.3	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.8	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	1.1	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	1.0	GO:0050918	positive chemotaxis(GO:0050918)
0.0	0.4	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.1	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.8	GO:0055007	cardiac muscle cell differentiation(GO:0055007)
0.0	0.6	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.9	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	1.6	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.3	1.0	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3	2.1	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3	1.1	GO:1990736	positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.2	4.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.2	1.4	GO:2000391	positive regulation of neutrophil extravasation(GO:2000391)
0.2	0.5	GO:0044209	AMP salvage(GO:0044209)
0.2	0.5	GO:0070632	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2	0.6	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.6	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.1	1.1	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1	0.7	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.1	GO:0031081	nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.1	1.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.4	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.1	0.6	GO:0060356	leucine import(GO:0060356)
0.1	0.4	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.4	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.4	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.1	1.1	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.7	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.5	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.1	0.5	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.2	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.1	2.3	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1	0.6	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.8	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	1.1	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	0.2	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1	0.4	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0060406	positive regulation of penile erection(GO:0060406)
0.1	0.7	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.2	GO:0051311	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1	0.3	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.1	0.4	GO:1901029	adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	0.5	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.1	0.5	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.2	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
0.1	0.1	GO:1990523	bone regeneration(GO:1990523)
0.1	0.3	GO:0015692	lead ion transport(GO:0015692)
0.1	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	1.2	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	1.3	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.2	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.8	GO:0090343	positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0	0.3	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.2	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.6	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.1	GO:0015920	leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.0	0.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:1904884	telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0	0.2	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.3	GO:0060453	regulation of gastric acid secretion(GO:0060453)
0.0	0.5	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.3	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.2	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.0	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.2	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.2	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.0	1.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.2	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.1	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	0.4	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.2	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:0043366	beta selection(GO:0043366)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0	0.5	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.4	GO:0007140	male meiosis(GO:0007140)
0.0	1.4	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.1	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.0	GO:0002434	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) T cell extravasation(GO:0072683) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.2	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.3	GO:1903432	regulation of TORC1 signaling(GO:1903432)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.2	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.2	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	1.3	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.1	GO:0042659	regulation of cell fate specification(GO:0042659)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	7.9	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	8.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	5.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	6.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	6.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	4.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	5.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	3.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	4.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	1.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2	5.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	7.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	3.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	2.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	4.0	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2	1.6	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.2	0.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.2	2.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	3.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	3.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	4.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	4.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	3.8	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	4.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	11.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	2.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	5.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	4.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	1.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	2.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	1.7	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	1.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	6.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	2.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	7.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	5.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	7.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.7	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	1.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	1.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	2.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	1.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	0.2	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	1.9	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	1.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.4	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	2.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	0.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	0.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	2.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	1.3	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	1.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	5.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.3	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1	0.9	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	1.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.9	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.5	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	1.0	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	1.2	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.2	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	4.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.8	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	2.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.9	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.8	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	1.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	1.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS	Genes involved in Metabolism of lipids and lipoproteins
0.0	0.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	1.5	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.0	0.8	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	2.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.6	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.6	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	3.0	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	8.3	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	1.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.4	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.2	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	2.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.0	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	1.2	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
16.6	66.4	GO:0035026	leading edge cell differentiation(GO:0035026)
16.3	48.9	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
7.2	21.7	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
7.1	21.4	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
5.5	16.6	GO:0002605	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
4.6	13.7	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
3.6	21.3	GO:0090131	mesenchyme migration(GO:0090131)
3.3	13.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
3.1	12.4	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
2.9	5.8	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
2.4	7.2	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
2.3	6.8	GO:1900158	negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
2.2	17.9	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
2.0	17.7	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278) chondroblast differentiation(GO:0060591)
1.9	34.3	GO:0007021	tubulin complex assembly(GO:0007021)
1.8	7.3	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
1.7	3.3	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
1.6	4.7	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
1.5	21.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.5	4.4	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.3	16.8	GO:0035372	protein localization to microtubule(GO:0035372)
1.3	7.7	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
1.1	4.6	GO:0009956	radial pattern formation(GO:0009956)
1.1	7.7	GO:0035331	negative regulation of hippo signaling(GO:0035331)
1.0	3.9	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.9	4.7	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.9	2.6	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.9	7.8	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.9	5.2	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.8	5.4	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8	3.8	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.8	16.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.7	0.7	GO:0072190	ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
0.7	30.4	GO:0035329	hippo signaling(GO:0035329)
0.7	3.6	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.7	8.5	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.7	2.7	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.6	0.6	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.6	5.3	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.6	12.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.6	10.1	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.6	3.9	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.6	18.8	GO:0060216	definitive hemopoiesis(GO:0060216)
0.6	2.2	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.5	5.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.5	2.7	GO:0021649	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.5	1.6	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5	1.5	GO:1903412	response to bile acid(GO:1903412)
0.5	17.2	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.5	4.8	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.5	1.9	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.5	10.4	GO:0003334	keratinocyte development(GO:0003334)
0.4	2.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.4	2.6	GO:0030035	microspike assembly(GO:0030035)
0.4	3.0	GO:0008218	bioluminescence(GO:0008218)
0.4	3.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.4	2.7	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.4	1.9	GO:0048014	Tie signaling pathway(GO:0048014)
0.4	1.1	GO:0007037	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.3	1.7	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3	1.4	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3	1.0	GO:0072275	branchiomeric skeletal muscle development(GO:0014707) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3	2.6	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.3	1.6	GO:0030070	insulin processing(GO:0030070)
0.3	1.2	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.3	2.7	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3	0.3	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.3	1.0	GO:1904457	glucosylceramide catabolic process(GO:0006680) termination of signal transduction(GO:0023021) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.2	1.0	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2	0.7	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2	1.8	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.2	2.0	GO:0000226	microtubule cytoskeleton organization(GO:0000226)
0.2	0.4	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.2	0.4	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
0.2	6.5	GO:0048747	muscle fiber development(GO:0048747)
0.2	3.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.2	4.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.2	1.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.2	0.7	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.2	2.7	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.2	0.2	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.2	4.2	GO:0007628	adult walking behavior(GO:0007628)
0.2	1.7	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.2	2.7	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2	1.5	GO:0060973	cell migration involved in heart development(GO:0060973)
0.2	0.5	GO:1904386	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.2	2.3	GO:0043586	tongue development(GO:0043586)
0.2	2.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.2	4.0	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2	75.7	GO:0006936	muscle contraction(GO:0006936)
0.1	1.4	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	1.3	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	1.4	GO:0007017	microtubule-based process(GO:0007017)
0.1	6.6	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.2	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.1	2.4	GO:0010842	retina layer formation(GO:0010842)
0.1	0.4	GO:0007266	Rho protein signal transduction(GO:0007266)
0.1	8.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	0.3	GO:0007538	primary sex determination(GO:0007538)
0.1	16.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	0.5	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.1	2.5	GO:0060325	face morphogenesis(GO:0060325)
0.1	0.9	GO:0007050	cell cycle arrest(GO:0007050)
0.1	3.4	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	1.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	0.4	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.3	GO:0045112	integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1	0.4	GO:0007097	nuclear migration(GO:0007097)
0.1	0.3	GO:0060536	cartilage morphogenesis(GO:0060536)
0.1	0.6	GO:0031642	negative regulation of myelination(GO:0031642)
0.1	0.3	GO:0098743	cell aggregation(GO:0098743)
0.1	1.4	GO:0016540	protein autoprocessing(GO:0016540)
0.1	0.3	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1	0.5	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.1	0.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	9.9	GO:0021987	cerebral cortex development(GO:0021987)
0.1	0.2	GO:0006738	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1	0.8	GO:1905247	positive regulation of beta-amyloid clearance(GO:1900223) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1	0.2	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1	0.7	GO:0030091	protein repair(GO:0030091)
0.1	0.8	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.1	3.2	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.1	0.5	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1	4.2	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.1	1.5	GO:0060065	uterus development(GO:0060065)
0.1	1.1	GO:0006751	glutathione catabolic process(GO:0006751)
0.1	0.2	GO:0039650	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1	7.0	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.1	6.8	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1	0.4	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.1	1.3	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.1	1.0	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	0.8	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1	1.0	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.6	GO:0030220	platelet formation(GO:0030220)
0.1	0.7	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.1	0.1	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.1	0.6	GO:0006702	androgen biosynthetic process(GO:0006702)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	2.8	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.5	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	5.9	GO:0000187	activation of MAPK activity(GO:0000187)
0.1	5.9	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.5	GO:0051764	actin crosslink formation(GO:0051764)
0.0	2.2	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0	5.6	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	3.5	GO:0045087	innate immune response(GO:0045087)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0	2.0	GO:0051693	actin filament capping(GO:0051693)
0.0	0.2	GO:0060467	negative regulation of fertilization(GO:0060467)
0.0	0.1	GO:0071934	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0	2.3	GO:0021549	cerebellum development(GO:0021549)
0.0	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	3.4	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	2.1	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	1.4	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	1.3	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.0	1.7	GO:0016032	viral process(GO:0016032) multi-organism cellular process(GO:0044764)
0.0	0.2	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.4	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0	0.8	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.2	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.3	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	7.0	GO:0006260	DNA replication(GO:0006260)
0.0	1.3	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.3	GO:0051931	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0	0.0	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.3	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0	0.0	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.9	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.0	0.3	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.6	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
1.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
1.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	1.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	2.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	3.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	1.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.9	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.3	9.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	7.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.3	5.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.3	1.8	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	13.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	8.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	4.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	4.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	1.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	3.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	4.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	3.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	3.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.3	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	7.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.0	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	2.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	0.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	2.4	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	1.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	0.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	3.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	2.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	2.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	2.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.6	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	2.7	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	1.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	2.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.7	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	1.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	2.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.8	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	1.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	3.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	2.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	2.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	6.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.3	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.9	18.8	GO:0051787	misfolded protein binding(GO:0051787)
0.9	8.6	GO:0045545	syndecan binding(GO:0045545)
0.7	4.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.6	6.8	GO:0042301	phosphate ion binding(GO:0042301)
0.5	2.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.4	12.5	GO:0005523	tropomyosin binding(GO:0005523)
0.4	1.3	GO:0070538	oleic acid binding(GO:0070538)
0.4	3.5	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.4	1.8	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4	2.2	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.3	2.0	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.3	2.0	GO:0004522	ribonuclease A activity(GO:0004522)
0.3	0.9	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.3	1.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3	1.8	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.3	1.8	GO:0048408	epidermal growth factor binding(GO:0048408)
0.2	0.8	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.2	0.6	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.2	1.4	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2	0.9	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	2.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.4	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	4.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	1.8	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	1.5	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.8	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	3.1	GO:0004697	protein kinase C activity(GO:0004697)
0.1	3.8	GO:0043394	proteoglycan binding(GO:0043394)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	1.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.9	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.4	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	1.6	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.1	0.7	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.3	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.4	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	0.7	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.1	0.3	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.8	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	1.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.8	GO:0042731	PH domain binding(GO:0042731)
0.1	1.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	1.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.9	GO:0045159	myosin II binding(GO:0045159)
0.1	0.8	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	1.1	GO:0017166	vinculin binding(GO:0017166)
0.1	1.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.6	GO:0032190	acrosin binding(GO:0032190)
0.1	7.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.8	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	0.3	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	0.3	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.1	0.4	GO:0030492	hemoglobin binding(GO:0030492)
0.1	3.1	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	5.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.9	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.8	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.9	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.2	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.1	3.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.2	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.1	5.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.3	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.4	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.8	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	1.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.2	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.2	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	1.1	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	6.3	GO:0005178	integrin binding(GO:0005178)
0.0	1.7	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.0	0.3	GO:0097643	amylin receptor activity(GO:0097643)
0.0	1.3	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.2	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	1.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	1.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	1.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0004797	thymidine kinase activity(GO:0004797)
0.0	0.6	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.7	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.5	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.6	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.1	GO:0001632	leukotriene B4 receptor activity(GO:0001632)
0.0	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.0	5.4	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	0.3	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.5	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.4	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.3	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	1.7	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	0.4	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.2	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.6	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0	0.1	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.0	0.9	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	0.3	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.1	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.6	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0052658	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.2	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0031005	filamin binding(GO:0031005)
0.0	0.0	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	3.9	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.3	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.6	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.8	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.5	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.5	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.4	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.8	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID ARF 3PATHWAY	Arf1 pathway
0.1	2.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	2.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	2.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	2.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	5.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	4.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	1.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	3.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	2.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.5	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	2.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	2.0	PID BMP PATHWAY	BMP receptor signaling
0.0	4.1	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.4	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.3	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	1.9	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.9	PID FOXO PATHWAY	FoxO family signaling
0.0	1.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	2.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	4.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID MYC PATHWAY	C-MYC pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.6	1.7	GO:0043132	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.4	1.2	GO:0061010	gall bladder development(GO:0061010)
0.3	2.2	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.3	1.3	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2	0.7	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2	1.5	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2	0.7	GO:2000525	dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2	0.6	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.2	0.6	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2	0.5	GO:0055073	cadmium ion homeostasis(GO:0055073)
0.2	0.5	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2	1.1	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2	0.5	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.1	0.7	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.4	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.1	0.8	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.9	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	1.3	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.6	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.6	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.5	GO:0000255	allantoin metabolic process(GO:0000255)
0.1	0.5	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1	0.6	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	0.8	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.6	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.1	0.3	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.3	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.6	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.9	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1	0.3	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1	0.5	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	0.3	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.1	0.8	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.5	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.2	GO:0045082	interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1	0.4	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1	0.8	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.4	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.2	GO:0071284	cellular response to lead ion(GO:0071284)
0.1	0.2	GO:1901189	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1	1.1	GO:0043248	proteasome assembly(GO:0043248)
0.1	0.8	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	0.2	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.1	0.2	GO:0021938	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.1	0.5	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.1	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	0.7	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	0.3	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1	0.2	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1	0.2	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.1	0.9	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.2	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	1.3	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.1	0.2	GO:0061030	axon target recognition(GO:0007412) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.3	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	0.3	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.5	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.1	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.0	0.4	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.6	GO:0008228	opsonization(GO:0008228)
0.0	0.3	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.4	GO:0097646	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0	0.2	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	1.9	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:1903464	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0	0.3	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.2	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0	0.2	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.1	GO:0002155	thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0	2.1	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.3	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.4	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.6	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.1	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	0.1	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.0	0.1	GO:0043449	olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0	0.1	GO:0072023	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0	0.1	GO:0035962	response to interleukin-13(GO:0035962)
0.0	0.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.2	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.2	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.7	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.4	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.2	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.4	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.6	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.0	0.1	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.2	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.0	0.1	GO:1990502	dense core granule maturation(GO:1990502)
0.0	1.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.2	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.1	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.3	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.3	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.0	GO:1905071	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0	0.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.2	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.0	GO:0015965	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0	0.2	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.0	GO:0018874	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.1	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.3	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.4	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.1	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0032006	regulation of TOR signaling(GO:0032006)
0.0	0.1	GO:0045794	negative regulation of cell volume(GO:0045794)
0.0	0.1	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.4	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.2	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	1.2	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.4	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	4.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	2.9	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	2.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	2.4	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	2.0	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	2.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	1.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.3	ST GAQ PATHWAY	G alpha q Pathway
0.0	4.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.2	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	1.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	2.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	0.8	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	3.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	1.9	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	2.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	2.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.9	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	1.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	1.5	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	1.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.9	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	2.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.6	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	2.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	0.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	2.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	0.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	2.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	6.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.9	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	2.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	3.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	2.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	2.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.0	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.9	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	2.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.1	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.8	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.6	1.7	GO:0051300	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.5	1.6	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4	1.3	GO:0005988	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.4	1.4	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.3	1.5	GO:0070842	aggresome assembly(GO:0070842)
0.3	1.7	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3	0.8	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.3	0.8	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2	1.2	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2	0.9	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.2	1.0	GO:0044336	embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.2	0.8	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.2	0.6	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2	0.6	GO:0048597	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2	0.9	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2	1.3	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.2	0.9	GO:1904693	midbrain morphogenesis(GO:1904693)
0.2	0.5	GO:1902356	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2	0.6	GO:0071895	odontoblast differentiation(GO:0071895)
0.2	1.7	GO:0006600	creatine metabolic process(GO:0006600)
0.2	0.6	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	1.0	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.6	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.1	0.7	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.1	1.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	2.6	GO:0006825	copper ion transport(GO:0006825)
0.1	0.3	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	0.5	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.4	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.3	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.1	0.2	GO:1905064	epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1	0.5	GO:0051013	microtubule severing(GO:0051013)
0.1	4.5	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	0.8	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	0.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1	0.3	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.5	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.1	0.3	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	0.7	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	0.7	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.1	0.3	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.2	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1	0.2	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1	0.3	GO:0007070	negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0	0.7	GO:0000165	MAPK cascade(GO:0000165)
0.0	0.2	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.2	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.7	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.1	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.0	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0	0.4	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.6	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.6	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.0	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0	0.8	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.7	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.6	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.7	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.2	GO:0060339	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.3	GO:0051005	endosome transport via multivesicular body sorting pathway(GO:0032509) negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.5	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.3	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0090625	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	1.4	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.2	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
0.0	1.0	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.5	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.4	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0072560	glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.0	0.2	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.0	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.0	0.1	GO:1902530	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0	0.5	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.5	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.3	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	0.7	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.4	GO:0098780	response to mitochondrial depolarisation(GO:0098780)
0.0	0.4	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.4	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	1.8	GO:0070268	cornification(GO:0070268)
0.0	0.5	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	0.2	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.3	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.2	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.7	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.7	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.3	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.4	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.7	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.0	GO:0031417	NatC complex(GO:0031417)
0.6	6.4	GO:0044666	MLL3/4 complex(GO:0044666)
0.6	2.3	GO:1990423	RZZ complex(GO:1990423)
0.6	5.7	GO:0000796	condensin complex(GO:0000796)
0.5	3.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.5	2.9	GO:0030893	meiotic cohesin complex(GO:0030893)
0.4	1.1	GO:0030689	Noc complex(GO:0030689)
0.4	1.1	GO:0034455	t-UTP complex(GO:0034455)
0.3	1.7	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.3	0.9	GO:0043291	RAVE complex(GO:0043291)
0.3	2.0	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.3	1.7	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.3	1.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2	1.7	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2	0.9	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.2	0.6	GO:1990130	Iml1 complex(GO:1990130)
0.2	3.5	GO:0034709	methylosome(GO:0034709)
0.2	0.9	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.2	0.9	GO:0033553	rDNA heterochromatin(GO:0033553)
0.2	0.5	GO:0031213	RSF complex(GO:0031213)
0.2	0.7	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	1.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.7	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.6	GO:0032021	NELF complex(GO:0032021)
0.1	2.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	0.8	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	0.4	GO:0033186	CAF-1 complex(GO:0033186)
0.1	1.0	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.3	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	2.7	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	1.4	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	0.5	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.4	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.1	1.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	1.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	2.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	2.8	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.4	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	1.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.2	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.5	GO:0019815	B cell receptor complex(GO:0019815)
0.1	12.5	GO:0000922	spindle pole(GO:0000922)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.5	GO:0097452	GAIT complex(GO:0097452)
0.1	0.7	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.1	0.4	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	1.5	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	0.3	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.5	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.1	0.3	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.2	GO:0060187	cell pole(GO:0060187)
0.1	0.4	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	0.3	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	0.8	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.7	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	0.3	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1	1.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	0.3	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.1	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	1.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.7	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.7	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.5	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	1.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.2	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.4	GO:0005840	ribosome(GO:0005840)
0.0	0.8	GO:0046930	pore complex(GO:0046930)
0.0	1.6	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.8	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	1.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.3	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.2	GO:0031201	SNARE complex(GO:0031201)
0.0	1.0	GO:0016592	mediator complex(GO:0016592)
0.0	0.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	1.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.5	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	1.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.7	GO:0030686	90S preribosome(GO:0030686)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	2.3	GO:0016234	inclusion body(GO:0016234)
0.0	1.0	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	8.1	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.5	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	6.7	GO:0031965	nuclear membrane(GO:0031965)
0.0	1.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.5	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.9	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.6	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	1.2	GO:0005814	centriole(GO:0005814)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.2	GO:0097440	apical dendrite(GO:0097440)
0.0	2.3	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.5	GO:0043679	axon terminus(GO:0043679)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	1.0	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.7	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.2	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.3	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	1.1	GO:0016605	PML body(GO:0016605)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.1	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.7	2.9	GO:0010159	specification of organ position(GO:0010159)
0.6	1.9	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.6	3.5	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.5	4.1	GO:1903273	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.4	1.3	GO:0001300	chronological cell aging(GO:0001300)
0.3	1.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.3	0.9	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.3	0.8	GO:0007037	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.2	0.9	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.2	0.9	GO:0034445	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2	0.9	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2	0.6	GO:2000591	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.2	1.5	GO:0008218	bioluminescence(GO:0008218)
0.2	0.8	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.2	1.0	GO:1903412	response to bile acid(GO:1903412)
0.2	0.6	GO:1903572	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2	0.6	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.2	0.2	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.2	0.7	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.2	0.5	GO:0061010	gall bladder development(GO:0061010)
0.2	0.4	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2	1.2	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.2	0.7	GO:0042412	taurine biosynthetic process(GO:0042412)
0.2	0.9	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.2	0.6	GO:0048749	compound eye development(GO:0048749)
0.2	0.6	GO:0035426	extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304)
0.2	1.1	GO:0010269	response to selenium ion(GO:0010269)
0.1	0.6	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.9	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.9	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.7	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.1	0.1	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1	0.4	GO:0050923	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.1	0.3	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1	0.4	GO:1904647	response to rotenone(GO:1904647)
0.1	0.4	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1	0.2	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1	0.2	GO:0036216	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	2.2	GO:0021930	cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1	0.7	GO:1903758	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1	0.1	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1	1.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	1.0	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.1	0.3	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1	3.2	GO:0010669	epithelial structure maintenance(GO:0010669)
0.1	0.3	GO:0021571	rhombomere 5 development(GO:0021571)
0.1	0.4	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.4	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1	1.2	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.6	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	1.3	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.3	GO:0052251	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1	0.3	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1	0.5	GO:0070560	protein secretion by platelet(GO:0070560)
0.1	0.3	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.1	0.3	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.1	0.1	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1	0.4	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.3	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	1.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.4	GO:0003408	optic cup formation involved in camera-type eye development(GO:0003408)
0.1	0.8	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1	0.3	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.1	0.6	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.5	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.6	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1	0.2	GO:0065001	specification of axis polarity(GO:0065001) negative regulation of tooth mineralization(GO:0070171)
0.1	0.3	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.1	3.3	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	0.7	GO:0060591	chondroblast differentiation(GO:0060591)
0.1	0.4	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.1	0.3	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	1.5	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.1	0.6	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.2	GO:0061188	negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1	0.5	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.3	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1	0.4	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.1	0.4	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.5	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.1	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.6	GO:0000050	urea cycle(GO:0000050)
0.1	0.3	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	0.2	GO:1904379	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1	0.4	GO:0030516	regulation of axon extension(GO:0030516)
0.1	0.1	GO:2001038	regulation of cellular response to drug(GO:2001038)
0.1	0.3	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.3	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.1	GO:0032423	regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.1	0.2	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1	0.3	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.1	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.1	0.2	GO:0031291	Ran protein signal transduction(GO:0031291)
0.1	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.3	GO:0044857	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1	0.3	GO:0071543	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1	0.9	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.1	0.3	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.1	0.1	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.1	0.8	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	0.8	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.1	GO:1903224	regulation of endodermal cell differentiation(GO:1903224) negative regulation of gastrulation(GO:2000542)
0.1	0.3	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0	0.4	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.0	0.3	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.6	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.2	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0	0.2	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
0.0	0.2	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.4	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.6	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.3	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.2	GO:0090131	mesenchyme migration(GO:0090131)
0.0	0.1	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.0	0.1	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0	1.0	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0060926	cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.0	0.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.2	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.1	GO:1902227	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.0	0.2	GO:0099538	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0	0.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.5	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.3	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.2	GO:1904693	midbrain morphogenesis(GO:1904693)
0.0	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0060179	male mating behavior(GO:0060179)
0.0	0.4	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.2	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.3	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	0.3	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0035905	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.1	GO:0033386	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0	0.2	GO:1904636	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0	0.1	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.0	0.8	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.3	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:1901899	positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0	0.3	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.6	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.1	GO:1904238	mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0034091	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.2	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.1	GO:0035811	negative regulation of urine volume(GO:0035811)
0.0	0.2	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.7	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.3	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.2	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.1	GO:2000254	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	1.6	GO:0008542	visual learning(GO:0008542)
0.0	0.2	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.1	GO:0019240	proline biosynthetic process(GO:0006561) citrulline biosynthetic process(GO:0019240) L-proline biosynthetic process(GO:0055129)
0.0	0.0	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593) negative regulation of lamellipodium organization(GO:1902744)
0.0	0.3	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.3	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.3	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.2	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.3	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.1	GO:0048075	positive regulation of eye pigmentation(GO:0048075)
0.0	0.1	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.2	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0	0.0	GO:1901204	regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.2	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.2	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.2	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.1	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	0.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.3	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.1	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.0	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.1	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.2	GO:0043087	regulation of GTPase activity(GO:0043087)
0.0	0.3	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.6	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.3	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	0.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0016129	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.4	GO:0048846	axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.1	GO:0099563	modification of synaptic structure(GO:0099563)
0.0	0.2	GO:0007569	cell aging(GO:0007569)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.3	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.2	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.0	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	0.0	GO:0019046	release from viral latency(GO:0019046)
0.0	0.2	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.2	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0	0.1	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0	0.1	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.0	0.2	GO:0002158	osteoclast proliferation(GO:0002158)
0.0	0.0	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0	0.5	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.4	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.0	0.1	GO:0021794	thalamus development(GO:0021794)
0.0	0.2	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	0.1	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0	0.0	GO:0003095	pressure natriuresis(GO:0003095)
0.0	0.1	GO:0046349	UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0	0.3	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.0	0.3	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0090280	positive regulation of calcium ion import(GO:0090280)
0.0	0.1	GO:1990668	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.0	0.2	GO:0006558	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.2	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.0	GO:0007538	primary sex determination(GO:0007538)
0.0	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.1	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.0	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.0	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.4	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.5	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0	0.0	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.4	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.0	0.1	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.0	0.2	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.3	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.0	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.2	GO:0051567	histone H3-K9 methylation(GO:0051567)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.0	GO:1902530	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.1	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.7	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.0	GO:0061358	negative regulation of Wnt protein secretion(GO:0061358)
0.0	0.4	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0039529	RIG-I signaling pathway(GO:0039529)
0.0	0.4	GO:0032570	response to progesterone(GO:0032570)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.4	REACTOME KINESINS	Genes involved in Kinesins
0.3	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	1.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.4	21.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.4	8.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	3.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	6.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	2.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	5.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.9	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1	3.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	3.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	4.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	5.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	3.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	2.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	2.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	13.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.9	35.0	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.7	6.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.7	9.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.6	23.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.6	24.9	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.5	1.1	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.5	5.2	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.5	10.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.5	6.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.5	6.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.5	13.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.4	7.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.4	10.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.4	0.9	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.4	7.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4	11.1	REACTOME KINESINS	Genes involved in Kinesins
0.4	11.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4	2.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.4	2.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4	1.9	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.4	14.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.4	6.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3	6.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.3	1.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.3	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.3	3.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.3	3.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.3	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	6.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3	5.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3	7.2	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.3	16.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	4.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	2.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.2	19.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.2	0.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	6.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.2	13.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.2	2.8	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.2	0.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	2.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	6.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2	0.5	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.2	7.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	0.2	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
0.2	6.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.2	6.7	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.2	2.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	2.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	2.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.2	1.1	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
0.2	15.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2	16.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	5.8	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.2	7.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.2	3.9	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2	3.3	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.2	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.2	2.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	11.3	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.2	4.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	2.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.2	1.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.2	12.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.2	4.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	5.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.7	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	2.7	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	3.9	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	2.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	3.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	3.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.0	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	4.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	4.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.9	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1	3.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	1.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	2.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	4.2	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.1	5.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	37.0	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.1	1.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	1.6	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.1	0.5	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	1.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	2.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	3.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.1	REACTOME DNA REPLICATION	Genes involved in DNA Replication
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	1.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	0.2	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.1	0.9	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	0.5	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	0.7	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	1.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	1.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	1.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	2.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	1.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	0.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	3.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.9	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	2.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.8	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	2.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	1.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	4.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	1.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.7	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.7	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.5	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.3	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.6	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.7	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.9	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	8.2	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.0	4.9	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.8	3.4	GO:1904457	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.8	6.3	GO:0060155	platelet dense granule organization(GO:0060155)
0.7	2.2	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.7	2.2	GO:1902445	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.7	2.0	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.4	1.1	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.4	1.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.4	5.5	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.3	1.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3	3.3	GO:0015889	cobalamin transport(GO:0015889)
0.3	1.8	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.3	2.1	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3	1.4	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3	0.3	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.3	0.8	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3	0.8	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.2	1.2	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2	0.6	GO:0061055	myotome development(GO:0061055)
0.2	0.9	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.2	0.8	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2	1.4	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.2	0.6	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.2	2.1	GO:0042118	endothelial cell activation(GO:0042118)
0.2	1.8	GO:0021769	orbitofrontal cortex development(GO:0021769)
0.2	0.5	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2	1.0	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
0.2	1.7	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.2	1.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.2	2.5	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	0.9	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.6	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.1	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.1	0.7	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.1	0.4	GO:0060535	trachea cartilage morphogenesis(GO:0060535)
0.1	0.4	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.1	0.4	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1	0.4	GO:2000777	positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1	0.9	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	0.6	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.1	0.2	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.1	0.6	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.1	GO:0006623	protein targeting to vacuole(GO:0006623)
0.1	1.3	GO:0051601	exocyst localization(GO:0051601)
0.1	0.3	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1	0.4	GO:0015808	L-alanine transport(GO:0015808)
0.1	0.4	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	4.4	GO:0090382	phagosome maturation(GO:0090382)
0.1	0.4	GO:1902908	regulation of melanosome transport(GO:1902908)
0.1	0.3	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.6	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.6	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	0.6	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.9	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.1	0.7	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.3	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	0.4	GO:1905123	regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1	0.4	GO:0000189	MAPK import into nucleus(GO:0000189)
0.1	0.7	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.3	GO:0010845	positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1	1.3	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.6	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1	0.5	GO:0030043	actin filament fragmentation(GO:0030043)
0.1	0.2	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.1	0.4	GO:0090649	rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1	0.8	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	1.0	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	0.2	GO:0018197	peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0009386	translational attenuation(GO:0009386)
0.1	0.4	GO:1902957	negative regulation of cellular respiration(GO:1901856) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1	0.3	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.2	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.1	0.8	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.1	0.3	GO:0090269	fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.1	0.8	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1	0.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.1	2.0	GO:0006295	nucleotide-excision repair, preincision complex stabilization(GO:0006293) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.7	GO:0070459	prolactin secretion(GO:0070459)
0.1	0.2	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.1	1.0	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.1	1.8	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.6	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.3	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	0.8	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.8	GO:0071285	cellular response to lithium ion(GO:0071285)
0.1	0.4	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.1	0.8	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.1	0.5	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	1.8	GO:0006491	N-glycan processing(GO:0006491)
0.1	1.5	GO:0070987	error-free translesion synthesis(GO:0070987)
0.1	0.3	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1	0.3	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.2	GO:0072683	T cell extravasation(GO:0072683)
0.1	0.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	0.4	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.2	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1	0.2	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1	0.2	GO:0035606	induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1	0.4	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.1	0.1	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1	0.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	0.3	GO:1902904	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.4	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0060592	mammary gland formation(GO:0060592)
0.0	0.4	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.9	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.2	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.7	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.0	0.4	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.7	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.3	GO:0051036	regulation of endosome size(GO:0051036)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.2	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0	0.7	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.4	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0002429	immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0	0.2	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.2	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.4	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.0	0.2	GO:2001137	positive regulation of actin filament depolymerization(GO:0030836) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) positive regulation of endocytic recycling(GO:2001137)
0.0	0.2	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.0	0.2	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.1	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.0	0.3	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.2	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0	0.1	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.1	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0	0.2	GO:0006740	NADPH regeneration(GO:0006740)
0.0	0.2	GO:0098502	DNA dephosphorylation(GO:0098502)
0.0	0.1	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0	0.9	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.3	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.0	GO:0048073	regulation of eye pigmentation(GO:0048073)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.4	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:1903935	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0	0.3	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0036369	transcription factor catabolic process(GO:0036369)
0.0	0.1	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0	0.4	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.2	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.4	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.6	GO:0098926	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.5	GO:0034030	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.1	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0	0.1	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.6	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0009181	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0	0.4	GO:1903432	regulation of TORC1 signaling(GO:1903432)
0.0	0.2	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	1.1	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.2	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.6	GO:0007565	female pregnancy(GO:0007565)
0.0	0.8	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.3	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.4	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.6	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	1.1	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.1	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.3	GO:0007097	nuclear migration(GO:0007097)
0.0	2.1	GO:0015992	proton transport(GO:0015992)
0.0	0.0	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.0	0.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	1.1	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.8	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.0	0.8	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.4	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.6	GO:0010761	fibroblast migration(GO:0010761)
0.0	2.1	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.7	GO:0048512	circadian behavior(GO:0048512)
0.0	0.1	GO:0001865	NK T cell differentiation(GO:0001865)
0.0	0.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.4	GO:1904031	positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0071344	diphosphate metabolic process(GO:0071344)
0.0	0.1	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.0	0.2	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.2	GO:0000715	protein deneddylation(GO:0000338) nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.0	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.3	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:0071468	cellular response to acidic pH(GO:0071468)
0.0	0.5	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.2	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.0	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.1	GO:0006068	ethanol metabolic process(GO:0006067) ethanol catabolic process(GO:0006068)
0.0	0.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	0.1	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0	0.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.4	GO:1904636	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.4	2.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4	2.5	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3	0.8	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2	0.7	GO:0019858	cytosine metabolic process(GO:0019858)
0.2	1.2	GO:0097338	response to clozapine(GO:0097338)
0.2	0.9	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.2	0.6	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	1.0	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2	0.8	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.2	0.5	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2	0.9	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.2	0.5	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	1.7	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.1	2.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.8	GO:0051036	regulation of endosome size(GO:0051036)
0.1	0.4	GO:0044209	AMP salvage(GO:0044209)
0.1	0.5	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.5	GO:0000255	allantoin metabolic process(GO:0000255)
0.1	0.4	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1	0.3	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.1	0.5	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.4	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.1	0.6	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.1	0.4	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.1	0.3	GO:1901355	response to rapamycin(GO:1901355)
0.1	0.9	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.6	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.1	0.5	GO:0006740	NADPH regeneration(GO:0006740)
0.1	0.6	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	0.3	GO:0031938	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1	0.3	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1	0.7	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1	0.3	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.1	0.3	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	3.8	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1	2.0	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	1.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.5	GO:0042256	mature ribosome assembly(GO:0042256)
0.1	1.6	GO:0090382	phagosome maturation(GO:0090382)
0.1	0.2	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	0.4	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.2	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.3	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.1	0.3	GO:0001906	cell killing(GO:0001906) killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1	0.3	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
0.1	0.4	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.2	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.1	0.3	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	0.5	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1	0.3	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.1	1.0	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1	0.2	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	0.6	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.4	GO:2000323	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1	0.5	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.5	GO:0016139	glycoside catabolic process(GO:0016139)
0.1	0.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.1	0.3	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.2	GO:0010845	positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1	0.2	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1	0.2	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1	0.2	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.1	0.7	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.5	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.4	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.1	0.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.2	GO:1903093	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1	0.2	GO:0043622	cortical microtubule organization(GO:0043622)
0.1	0.4	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.1	0.2	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.1	0.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.2	GO:0071409	negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.1	0.3	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.1	0.4	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.4	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	0.5	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1	0.5	GO:0021769	orbitofrontal cortex development(GO:0021769)
0.1	0.6	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	0.2	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.2	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	0.3	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0	0.3	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.4	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.2	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.4	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.6	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.0	0.2	GO:0031291	Ran protein signal transduction(GO:0031291)
0.0	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.1	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0	0.4	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.3	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:1903059	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0	0.3	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0	0.7	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.2	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0	0.2	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.3	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.1	GO:0061198	fungiform papilla formation(GO:0061198)
0.0	0.2	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0	0.5	GO:0051451	myoblast migration(GO:0051451)
0.0	0.6	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	1.8	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.2	GO:0072396	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.6	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.2	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0021718	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0	0.0	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.2	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.8	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.2	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	0.3	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.2	GO:0072553	terminal button organization(GO:0072553)
0.0	0.1	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.6	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.4	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.6	GO:1903432	regulation of TORC1 signaling(GO:1903432)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.6	GO:0000154	rRNA modification(GO:0000154)
0.0	0.7	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.0	0.4	GO:0014029	neural crest formation(GO:0014029)
0.0	0.3	GO:0051601	exocyst localization(GO:0051601)
0.0	0.3	GO:0033572	transferrin transport(GO:0033572)
0.0	0.3	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0036090	cleavage furrow ingression(GO:0036090)
0.0	0.7	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0	0.2	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.1	GO:1903674	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0	0.1	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.0	0.1	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.2	GO:2001169	regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171)
0.0	0.1	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.5	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	1.8	GO:0010038	response to metal ion(GO:0010038)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.0	0.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0070384	Harderian gland development(GO:0070384)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.0	0.2	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.0	GO:1901859	negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.1	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.0	0.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.1	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.3	GO:0007097	nuclear migration(GO:0007097)
0.0	0.2	GO:0006069	ethanol oxidation(GO:0006069)
0.0	1.0	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.1	GO:1902915	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.0	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0	0.1	GO:0015866	adenine transport(GO:0015853) ADP transport(GO:0015866) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0048691	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:0072023	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0	0.2	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.0	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.0	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.2	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	0.3	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.6	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.2	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.0	0.1	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.1	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0	0.0	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.0	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	1.1	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	1.0	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.1	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0	0.3	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.0	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.0	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.2	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0	0.3	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.3	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.6	GO:0002209	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.1	GO:0035247	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.0	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.7	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.2	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.4	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.2	GO:0031960	response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.0	0.1	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0030043	actin filament fragmentation(GO:0030043)
0.0	0.1	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.0	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.0	0.0	GO:0006294	nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0	0.0	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.3	0.9	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.9	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2	1.5	GO:0034235	GPI anchor binding(GO:0034235)
0.2	1.8	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.4	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.6	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1	0.3	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.5	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.1	0.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.6	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.5	GO:0098821	BMP receptor activity(GO:0098821)
0.1	0.4	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	0.2	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	7.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.5	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	1.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.1	0.3	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.3	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.3	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1	0.2	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.1	0.4	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.2	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1	0.4	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.4	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0098770	FBXO family protein binding(GO:0098770)
0.0	0.6	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	1.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0032810	sterol response element binding(GO:0032810)
0.0	0.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.0	0.9	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.7	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.2	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.4	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.2	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.1	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.6	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.5	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0043028	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.4	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.4	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.3	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.8	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.7	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.9	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0000406	heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0	0.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0	0.5	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0035500	MH2 domain binding(GO:0035500)
0.0	0.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.1	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.1	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0	0.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.0	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.8	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.8	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	1.3	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.2	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	1.3	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.3	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	0.4	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.2	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	1.3	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.5	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.7	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.1	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.3	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.0	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	0.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
1.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
1.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	18.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.3	6.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	5.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	0.9	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	12.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	7.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	3.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	5.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2	3.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	2.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	1.6	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	4.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	6.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.9	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	3.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	0.8	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	1.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.6	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	3.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	2.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	3.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	6.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.9	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	3.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	2.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.9	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	2.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.3	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.7	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	1.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.2	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	2.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	3.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
6.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
2.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
1.5	PID IL2 1PATHWAY	IL2-mediated signaling events
1.9	PID ATF2 PATHWAY	ATF-2 transcription factor network
1.1	PID PLK1 PATHWAY	PLK1 signaling events
1.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	6.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.9	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	2.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	4.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.8	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.6	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	17.4	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
3.6	25.4	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
3.3	9.8	GO:0004157	dihydropyrimidinase activity(GO:0004157)
3.1	18.7	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
2.7	13.4	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
2.5	17.6	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
2.3	16.2	GO:0035614	snRNA stem-loop binding(GO:0035614)
2.2	13.0	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
2.1	2.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
2.1	10.6	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
2.0	7.8	GO:0043398	HLH domain binding(GO:0043398)
2.0	33.2	GO:0017154	semaphorin receptor activity(GO:0017154)
1.9	1.9	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
1.9	5.7	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.9	13.0	GO:0047134	protein-disulfide reductase activity(GO:0047134)
1.8	20.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
1.8	14.6	GO:0045159	myosin II binding(GO:0045159)
1.8	10.8	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.8	16.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.8	23.1	GO:0046870	cadmium ion binding(GO:0046870)
1.7	1.7	GO:0016866	intramolecular transferase activity(GO:0016866)
1.6	6.5	GO:0070051	fibrinogen binding(GO:0070051)
1.6	8.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
1.6	4.9	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
1.6	8.1	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
1.6	6.5	GO:0019770	IgG receptor activity(GO:0019770)
1.6	11.0	GO:0016015	morphogen activity(GO:0016015)
1.6	6.2	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
1.5	6.2	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
1.5	6.1	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.5	56.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
1.5	24.2	GO:0008179	adenylate cyclase binding(GO:0008179)
1.4	7.1	GO:0016403	dimethylargininase activity(GO:0016403)
1.4	31.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
1.3	4.0	GO:0032184	SUMO polymer binding(GO:0032184)
1.3	4.0	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
1.3	3.9	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.3	3.9	GO:0035501	MH1 domain binding(GO:0035501)
1.3	23.0	GO:0048185	activin binding(GO:0048185)
1.3	12.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
1.3	7.6	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3	6.3	GO:0043237	laminin-1 binding(GO:0043237)
1.2	3.7	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
1.2	3.7	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.2	3.6	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.2	4.8	GO:0004850	uridine phosphorylase activity(GO:0004850)
1.2	52.5	GO:0003785	actin monomer binding(GO:0003785)
1.2	4.8	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.2	7.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
1.2	9.3	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
1.1	26.4	GO:0017166	vinculin binding(GO:0017166)
1.1	3.4	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
1.1	5.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
1.1	3.4	GO:0098634	protein binding involved in cell-matrix adhesion(GO:0098634)
1.1	3.4	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
1.1	27.9	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
1.1	11.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.1	5.5	GO:0015307	drug:proton antiporter activity(GO:0015307)
1.1	3.2	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
1.0	5.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
1.0	4.1	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
1.0	18.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.0	3.1	GO:0033823	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
1.0	4.0	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
1.0	1.0	GO:0017002	activin-activated receptor activity(GO:0017002)
1.0	3.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
1.0	3.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
1.0	8.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
1.0	5.8	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
1.0	8.6	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
1.0	23.9	GO:0043394	proteoglycan binding(GO:0043394)
1.0	22.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.0	1.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.9	0.9	GO:0050693	LBD domain binding(GO:0050693)
0.9	9.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.9	4.6	GO:0004771	sterol esterase activity(GO:0004771)
0.9	5.5	GO:0039552	RIG-I binding(GO:0039552)
0.9	2.7	GO:0030984	kininogen binding(GO:0030984)
0.9	4.5	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.9	2.7	GO:0052894	norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.9	13.9	GO:0070411	I-SMAD binding(GO:0070411)
0.9	40.9	GO:0030546	receptor activator activity(GO:0030546)
0.9	6.9	GO:0050692	DBD domain binding(GO:0050692)
0.9	6.9	GO:0045499	chemorepellent activity(GO:0045499)
0.9	2.6	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.8	4.2	GO:0051022	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.8	10.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.8	3.3	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.8	2.5	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.8	3.3	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.8	3.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8	3.3	GO:0038132	neuregulin binding(GO:0038132)
0.8	4.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.8	3.2	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.8	28.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.8	0.8	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.8	2.4	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.8	2.3	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.8	3.9	GO:0052833	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.8	3.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.8	7.6	GO:0042731	PH domain binding(GO:0042731)
0.8	21.9	GO:0070064	proline-rich region binding(GO:0070064)
0.7	4.5	GO:0003998	acylphosphatase activity(GO:0003998)
0.7	2.2	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.7	5.8	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.7	4.3	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7	3.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.7	2.9	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.7	2.1	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.7	8.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.7	7.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.7	10.6	GO:0043236	laminin binding(GO:0043236)
0.7	2.8	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.7	2.1	GO:0032093	SAM domain binding(GO:0032093)
0.7	2.7	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.7	6.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.7	15.6	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.7	3.4	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.7	3.4	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.7	55.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.7	9.8	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.7	3.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.7	6.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.7	3.3	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.7	8.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.6	2.6	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.6	0.6	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.6	0.6	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.6	5.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.6	1.3	GO:0097001	ceramide binding(GO:0097001)
0.6	15.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.6	2.5	GO:0048408	epidermal growth factor binding(GO:0048408)
0.6	6.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.6	1.8	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.6	5.5	GO:0001968	fibronectin binding(GO:0001968)
0.6	2.4	GO:0047298	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.6	50.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.6	12.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.6	1.8	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.6	1.8	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.6	3.5	GO:0046979	TAP2 binding(GO:0046979)
0.6	4.6	GO:0008131	primary amine oxidase activity(GO:0008131)
0.6	1.7	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.6	15.7	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6	1.7	GO:0070984	SET domain binding(GO:0070984)
0.6	3.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.6	0.6	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.6	0.6	GO:0016623	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.6	2.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.5	6.0	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.5	1.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.5	2.7	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.5	2.2	GO:0004803	transposase activity(GO:0004803)
0.5	2.2	GO:0086077	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.5	1.6	GO:1904288	BAT3 complex binding(GO:1904288)
0.5	1.6	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.5	11.7	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.5	11.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.5	1.6	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.5	0.5	GO:0070697	activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)
0.5	7.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.5	0.5	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.5	5.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.5	0.5	GO:0042910	xenobiotic transporter activity(GO:0042910)
0.5	2.6	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.5	2.0	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.5	1.5	GO:0017018	myosin phosphatase activity(GO:0017018)
0.5	2.0	GO:0031716	calcitonin receptor binding(GO:0031716)
0.5	2.0	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.5	7.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.5	1.5	GO:0035473	lipase binding(GO:0035473)
0.5	1.5	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.5	3.5	GO:0046923	ER retention sequence binding(GO:0046923)
0.5	2.5	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.5	2.0	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.5	1.5	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.5	2.0	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.5	3.5	GO:0004532	exoribonuclease activity(GO:0004532)
0.5	7.9	GO:0043495	protein anchor(GO:0043495)
0.5	3.4	GO:0003680	AT DNA binding(GO:0003680)
0.5	1.5	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.5	2.0	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.5	1.0	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.5	1.4	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.5	1.4	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.5	2.4	GO:0004359	glutaminase activity(GO:0004359)
0.5	2.4	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.5	2.8	GO:0004630	phospholipase D activity(GO:0004630)
0.5	1.9	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5	1.4	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.5	0.5	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.5	3.7	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.5	2.8	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.5	1.4	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.4	1.8	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.4	3.6	GO:0034235	GPI anchor binding(GO:0034235)
0.4	44.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.4	1.3	GO:0030350	iron-responsive element binding(GO:0030350)
0.4	1.8	GO:0004461	lactose synthase activity(GO:0004461)
0.4	1.3	GO:0071209	U7 snRNA binding(GO:0071209)
0.4	3.9	GO:0004985	opioid receptor activity(GO:0004985)
0.4	20.5	GO:0015485	cholesterol binding(GO:0015485)
0.4	4.8	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.4	3.5	GO:0034452	dynactin binding(GO:0034452)
0.4	2.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.4	5.6	GO:0001223	transcription coactivator binding(GO:0001223)
0.4	15.9	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.4	7.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.4	0.9	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.4	10.2	GO:0016805	dipeptidase activity(GO:0016805)
0.4	6.8	GO:0019841	retinol binding(GO:0019841)
0.4	0.4	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.4	1.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.4	1.2	GO:0050135	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.4	2.5	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.4	1.6	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4	1.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.4	2.9	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.4	2.4	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.4	2.4	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4	1.6	GO:0017089	glycolipid transporter activity(GO:0017089)
0.4	47.7	GO:0005178	integrin binding(GO:0005178)
0.4	2.4	GO:0034711	inhibin binding(GO:0034711)
0.4	0.8	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.4	6.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.4	2.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.4	3.9	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.4	5.8	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.4	8.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.4	0.8	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.4	1.5	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.4	8.0	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.4	4.2	GO:0046790	virion binding(GO:0046790)
0.4	1.1	GO:0004913	interleukin-4 receptor activity(GO:0004913)
0.4	1.9	GO:0097016	L27 domain binding(GO:0097016)
0.4	5.9	GO:0070410	co-SMAD binding(GO:0070410)
0.4	1.5	GO:0047708	biotinidase activity(GO:0047708)
0.4	26.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.4	5.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.4	2.9	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.4	8.0	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.4	3.7	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.4	1.1	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.4	4.0	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.4	3.6	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4	0.7	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.4	4.3	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4	3.9	GO:0039706	co-receptor binding(GO:0039706)
0.4	0.4	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4	0.4	GO:0035613	RNA stem-loop binding(GO:0035613)
0.4	1.1	GO:0035500	MH2 domain binding(GO:0035500)
0.4	2.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.3	2.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.3	20.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.3	0.7	GO:0070905	serine binding(GO:0070905)
0.3	7.9	GO:0004383	guanylate cyclase activity(GO:0004383)
0.3	12.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3	2.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.3	3.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3	1.4	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.3	1.7	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3	1.0	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.3	1.7	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.3	5.3	GO:0008432	JUN kinase binding(GO:0008432)
0.3	5.3	GO:0031005	filamin binding(GO:0031005)
0.3	6.9	GO:0017081	chloride channel regulator activity(GO:0017081)
0.3	1.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.3	2.0	GO:0017022	myosin binding(GO:0017022)
0.3	5.2	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.3	23.2	GO:0017048	Rho GTPase binding(GO:0017048)
0.3	1.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	1.6	GO:0016405	CoA-ligase activity(GO:0016405)
0.3	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.3	1.0	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.3	10.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.3	1.3	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.3	2.9	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.3	0.9	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.3	2.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3	1.9	GO:0004522	ribonuclease A activity(GO:0004522)
0.3	1.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3	0.9	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.3	4.6	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3	1.8	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.3	7.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.3	6.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.3	1.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.3	9.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.3	0.9	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3	8.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.3	1.8	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.3	0.9	GO:0030366	molybdopterin synthase activity(GO:0030366)
0.3	4.7	GO:0008494	translation activator activity(GO:0008494)
0.3	1.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3	0.9	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.3	0.3	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.3	0.8	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.3	2.5	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.3	0.6	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.3	7.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.3	8.1	GO:0070412	R-SMAD binding(GO:0070412)
0.3	0.8	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.3	0.6	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.3	0.8	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.3	2.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.3	1.1	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.3	1.6	GO:0070182	DNA polymerase binding(GO:0070182)
0.3	7.1	GO:0042056	chemoattractant activity(GO:0042056)
0.3	0.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.3	1.9	GO:0032051	clathrin light chain binding(GO:0032051)
0.3	1.9	GO:0004017	adenylate kinase activity(GO:0004017)
0.3	0.8	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.3	0.3	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.3	7.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.3	0.5	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3	0.3	GO:0090079	translation repressor activity, nucleic acid binding(GO:0000900) translation regulator activity, nucleic acid binding(GO:0090079)
0.3	3.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.3	0.8	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3	12.1	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.3	0.8	GO:0004802	transketolase activity(GO:0004802)
0.3	1.5	GO:0051011	microtubule minus-end binding(GO:0051011)
0.3	0.8	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3	0.5	GO:0004064	arylesterase activity(GO:0004064)
0.3	1.3	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.3	1.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.3	1.0	GO:0044548	S100 protein binding(GO:0044548)
0.3	0.8	GO:0031685	adenosine receptor binding(GO:0031685)
0.3	3.5	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.3	1.0	GO:0004743	pyruvate kinase activity(GO:0004743)
0.2	1.0	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.2	1.2	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.2	2.5	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2	7.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.2	1.9	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	7.0	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.2	0.5	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2	3.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	0.7	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2	0.7	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.2	0.9	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.2	1.6	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2	0.7	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.2	0.7	GO:0016297	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.2	0.9	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.2	5.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.2	1.3	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2	2.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2	33.6	GO:0017137	Rab GTPase binding(GO:0017137)
0.2	0.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	0.9	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2	0.6	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2	4.0	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	0.4	GO:0098821	BMP receptor activity(GO:0098821)
0.2	2.5	GO:0017080	sodium channel regulator activity(GO:0017080)
0.2	2.0	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.2	2.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	0.4	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.2	1.4	GO:0001727	lipid kinase activity(GO:0001727)
0.2	1.8	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.2	0.4	GO:0031402	sodium ion binding(GO:0031402)
0.2	2.2	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
0.2	1.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2	5.7	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2	0.4	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2	2.5	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.2	2.9	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.2	0.6	GO:0019961	interferon binding(GO:0019961)
0.2	0.6	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2	1.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.2	1.0	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.2	3.8	GO:0045504	dynein heavy chain binding(GO:0045504)
0.2	0.6	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2	4.9	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2	0.9	GO:0008172	S-methyltransferase activity(GO:0008172)
0.2	0.8	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.2	0.6	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2	0.6	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2	1.3	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.2	0.2	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.2	0.4	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.2	3.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.2	0.7	GO:0038181	bile acid receptor activity(GO:0038181)
0.2	0.5	GO:0034584	piRNA binding(GO:0034584)
0.2	0.4	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2	0.5	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.2	0.4	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
0.2	4.2	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2	0.9	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.2	1.4	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.2	1.8	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2	4.8	GO:0017075	syntaxin-1 binding(GO:0017075)
0.2	0.5	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.2	1.4	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.2	0.4	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.2	0.7	GO:0017040	ceramidase activity(GO:0017040)
0.2	7.3	GO:0032947	protein complex scaffold(GO:0032947)
0.2	19.0	GO:0044325	ion channel binding(GO:0044325)
0.2	1.6	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.2	1.6	GO:0015248	sterol transporter activity(GO:0015248)
0.2	0.7	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.2	0.2	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2	3.6	GO:0050811	GABA receptor binding(GO:0050811)
0.2	0.2	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.2	1.5	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.2	3.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2	0.8	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2	0.2	GO:0032810	sterol response element binding(GO:0032810)
0.2	1.5	GO:0043426	MRF binding(GO:0043426)
0.2	1.0	GO:0004882	androgen receptor activity(GO:0004882)
0.2	2.3	GO:0005522	profilin binding(GO:0005522)
0.2	1.6	GO:0015929	hexosaminidase activity(GO:0015929)
0.2	5.7	GO:0050699	WW domain binding(GO:0050699)
0.2	5.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.2	2.8	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.2	0.8	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.2	31.8	GO:0005096	GTPase activator activity(GO:0005096)
0.2	1.0	GO:0008142	oxysterol binding(GO:0008142)
0.2	0.5	GO:0051748	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2	0.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.2	1.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.2	1.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	0.6	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	0.5	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2	0.9	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2	0.6	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.2	0.8	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.2	0.5	GO:0098625	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2	0.5	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.9	GO:0000146	microfilament motor activity(GO:0000146)
0.1	2.4	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.4	GO:0019534	toxin transporter activity(GO:0019534)
0.1	0.4	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	0.6	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
0.1	1.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.4	GO:0036122	BMP binding(GO:0036122)
0.1	0.3	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	0.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	3.9	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	3.8	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.6	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	1.8	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.3	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.1	3.7	GO:0005518	collagen binding(GO:0005518)
0.1	0.5	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.4	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.1	0.1	GO:0070728	leucine binding(GO:0070728)
0.1	1.2	GO:0019215	intermediate filament binding(GO:0019215)
0.1	1.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	2.1	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1	2.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.5	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.4	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.1	0.4	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.8	GO:0050294	steroid sulfotransferase activity(GO:0050294)
0.1	0.5	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	1.2	GO:0032027	myosin light chain binding(GO:0032027)
0.1	0.2	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.1	0.6	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	41.3	GO:0045296	cadherin binding(GO:0045296)
0.1	0.7	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.7	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1	1.0	GO:0015923	mannosidase activity(GO:0015923)
0.1	1.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	3.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1	2.0	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	0.5	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.6	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	0.1	GO:0042806	fucose binding(GO:0042806)
0.1	0.8	GO:0004645	phosphorylase activity(GO:0004645)
0.1	1.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	0.8	GO:1990405	protein antigen binding(GO:1990405)
0.1	0.7	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.3	GO:0033592	RNA strand annealing activity(GO:0033592)
0.1	0.2	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	3.8	GO:0019905	syntaxin binding(GO:0019905)
0.1	0.3	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1	1.5	GO:0070403	NAD+ binding(GO:0070403)
0.1	0.2	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	1.2	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.6	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1	0.6	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	1.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	2.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.8	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.3	GO:0032089	NACHT domain binding(GO:0032089)
0.1	0.4	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	0.9	GO:0043422	protein kinase B binding(GO:0043422)
0.1	1.5	GO:0017091	AU-rich element binding(GO:0017091)
0.1	2.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	1.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.2	GO:0070402	NADPH binding(GO:0070402)
0.1	0.3	GO:0031711	angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.1	0.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.3	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1	0.9	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.5	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	8.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.5	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.9	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.1	0.6	GO:0033989	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1	0.4	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.7	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.3	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.3	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	0.9	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	0.6	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	2.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.3	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.5	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	2.8	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	0.3	GO:0004608	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	0.1	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	0.3	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.1	0.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	13.8	GO:0008022	protein C-terminus binding(GO:0008022)
0.1	0.5	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	0.4	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	2.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	1.0	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.1	2.1	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.1	2.8	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	2.0	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.3	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.7	GO:0035877	death effector domain binding(GO:0035877)
0.1	0.5	GO:0032190	acrosin binding(GO:0032190)
0.1	0.2	GO:0004947	bradykinin receptor activity(GO:0004947)
0.1	2.2	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	1.1	GO:0005112	Notch binding(GO:0005112)
0.1	0.2	GO:0030507	spectrin binding(GO:0030507)
0.1	1.8	GO:0001972	retinoic acid binding(GO:0001972)
0.1	0.9	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.6	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.3	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.3	GO:0052796	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	0.3	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	0.7	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.6	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	3.4	GO:0019838	growth factor binding(GO:0019838)
0.1	0.7	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.3	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.1	0.2	GO:0035671	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	1.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	5.0	GO:0017124	SH3 domain binding(GO:0017124)
0.1	0.3	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1	2.1	GO:0043621	protein self-association(GO:0043621)
0.1	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.2	GO:0008431	vitamin E binding(GO:0008431)
0.1	1.2	GO:0004629	phospholipase C activity(GO:0004629)
0.1	0.7	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	0.5	GO:0008097	5S rRNA binding(GO:0008097)
0.1	0.2	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	1.4	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	14.3	GO:0003779	actin binding(GO:0003779)
0.1	0.2	GO:0015616	DNA translocase activity(GO:0015616)
0.1	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.2	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.9	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	0.9	GO:0003924	GTPase activity(GO:0003924)
0.1	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	0.2	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.7	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.1	0.7	GO:0048038	quinone binding(GO:0048038)
0.1	0.4	GO:1990932	5.8S rRNA binding(GO:1990932)
0.1	1.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.1	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	0.2	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1	26.1	GO:0005509	calcium ion binding(GO:0005509)
0.1	1.0	GO:0008171	O-methyltransferase activity(GO:0008171)
0.1	1.2	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.1	0.2	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	3.1	GO:0008013	beta-catenin binding(GO:0008013)
0.1	0.3	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	0.1	GO:0001083	transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.1	4.4	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.1	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.2	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1	1.7	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	0.3	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1	0.5	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	0.5	GO:0005537	mannose binding(GO:0005537)
0.1	1.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	0.2	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	0.5	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.2	GO:0016429	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.7	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	1.3	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.8	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	1.4	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0	0.8	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.9	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	0.1	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.0	0.3	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.3	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	1.7	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.2	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.0	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	1.0	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.1	GO:0001163	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.3	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.0	0.0	GO:0015295	solute:proton symporter activity(GO:0015295)
0.0	0.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.3	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0002046	opsin binding(GO:0002046)
0.0	0.7	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.4	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.5	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	3.1	GO:0005179	hormone activity(GO:0005179)
0.0	0.1	GO:0004797	thymidine kinase activity(GO:0004797)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	2.6	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.3	GO:0019956	chemokine binding(GO:0019956)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.2	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.0	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.6	GO:0051213	dioxygenase activity(GO:0051213)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.9	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.2	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.2	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0042805	actinin binding(GO:0042805)
0.0	0.0	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.0	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.1	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.0	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.8	2.5	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5	3.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.4	1.9	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.4	1.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.3	0.9	GO:0002113	interleukin-33 binding(GO:0002113)
0.3	0.9	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3	2.4	GO:0004064	arylesterase activity(GO:0004064)
0.3	1.0	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.3	0.8	GO:0032767	copper-dependent protein binding(GO:0032767)
0.2	1.2	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.2	0.7	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.2	3.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	1.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.2	0.8	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	2.5	GO:0004875	complement receptor activity(GO:0004875)
0.2	4.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	0.9	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2	5.2	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.2	2.6	GO:0045499	chemorepellent activity(GO:0045499)
0.2	2.1	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.2	0.9	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	1.8	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.4	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1	1.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	1.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	5.2	GO:0050699	WW domain binding(GO:0050699)
0.1	1.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	3.1	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.4	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	0.6	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	4.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.3	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	0.8	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	2.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.5	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	0.4	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.6	GO:0005497	androgen binding(GO:0005497)
0.1	0.7	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	0.4	GO:0034046	poly(G) binding(GO:0034046)
0.1	2.1	GO:0042605	peptide antigen binding(GO:0042605)
0.1	1.7	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.8	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	3.2	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	0.6	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	1.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.8	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	0.4	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0	0.1	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.8	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	1.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	1.0	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.6	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.8	GO:0001848	complement binding(GO:0001848)
0.0	0.8	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	1.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.4	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.5	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	2.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.2	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.9	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.8	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.5	GO:0042169	SH2 domain binding(GO:0042169)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	10.7	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	3.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	3.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	5.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	2.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.9	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	3.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	4.4	PID AURORA A PATHWAY	Aurora A signaling
0.1	4.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	1.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	3.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	1.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	3.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	3.2	PID FOXO PATHWAY	FoxO family signaling
0.0	3.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	2.2	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.8	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	1.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.0	PID ATM PATHWAY	ATM pathway
0.0	2.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.8	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.4	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.5	PID E2F PATHWAY	E2F transcription factor network
0.0	0.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.5	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.9	PID ATR PATHWAY	ATR signaling pathway
0.0	2.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.6	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.5	PID FGF PATHWAY	FGF signaling pathway
0.0	0.4	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.2	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.2	3.2	GO:0005577	fibrinogen complex(GO:0005577)
0.2	1.2	GO:1990037	Lewy body core(GO:1990037)
0.1	0.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.3	GO:0071953	elastic fiber(GO:0071953)
0.0	2.9	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.6	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.9	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	1.4	GO:0016459	myosin complex(GO:0016459)
0.0	1.0	GO:0045095	keratin filament(GO:0045095)
0.0	1.7	GO:0001650	fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.8	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.4	1.3	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3	1.7	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2	1.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2	1.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.1	0.6	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1	0.7	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.1	0.7	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.4	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.4	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	0.5	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	1.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.1	0.4	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.9	GO:0004526	ribonuclease P activity(GO:0004526)
0.1	0.2	GO:0016749	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0	0.3	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.0	0.8	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.6	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.4	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.6	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	1.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.8	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.7	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	1.6	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.9	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.6	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	2.7	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.0	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.9	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.8	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	4.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.5	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	1.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	2.3	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	1.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	4.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.7	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.2	0.9	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2	0.5	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.6	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	1.5	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.8	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	1.4	GO:0030957	Tat protein binding(GO:0030957)
0.1	1.7	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1	0.4	GO:0039552	RIG-I binding(GO:0039552)
0.1	0.8	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1	0.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.2	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.4	GO:0052656	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1	0.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	1.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.2	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.1	0.2	GO:0097677	STAT family protein binding(GO:0097677)
0.1	0.5	GO:0043426	MRF binding(GO:0043426)
0.1	0.3	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.3	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	0.2	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	0.4	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.2	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.9	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.0	0.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.4	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.1	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.0	0.2	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0	0.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0	0.5	GO:0031386	protein tag(GO:0031386)
0.0	0.3	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0008940	nitrate reductase activity(GO:0008940)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	1.4	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.3	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.3	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	0.4	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	0.4	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.2	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.1	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0	0.3	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.0	0.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.0	0.1	GO:0004137	deoxycytidine kinase activity(GO:0004137)
0.0	0.2	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.0	0.1	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.4	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.0	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.5	GO:0031489	myosin V binding(GO:0031489)
0.0	0.1	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.8	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.2	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.7	GO:0070888	E-box binding(GO:0070888)
0.0	0.3	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0032093	SAM domain binding(GO:0032093)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.3	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.3	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.4	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	22.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.7	13.0	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	3.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	2.8	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	1.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	2.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	3.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	4.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	3.3	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	17.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	4.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	3.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	2.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	4.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	4.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	7.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	1.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	4.2	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	2.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.8	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	2.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.6	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.6	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	2.6	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.8	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	12.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	26.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	11.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3	6.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	5.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	12.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	4.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	1.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	4.4	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.4	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	1.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	2.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.3	GO:0004998	transferrin receptor activity(GO:0004998)
0.1	0.6	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.2	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1	0.4	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0	0.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	0.4	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.1	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.0	GO:0018685	alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0	0.0	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.6	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.4	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	13.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.5	6.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	3.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	5.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	2.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	0.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.6	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	1.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	2.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	1.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.6	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	1.0	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.0	1.1	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.1	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0	0.8	GO:0031143	pseudopodium(GO:0031143)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.5	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.3	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.2	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.0	11.9	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
2.5	15.1	GO:0061518	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.2	6.5	GO:0001300	chronological cell aging(GO:0001300)
1.5	9.1	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
1.5	4.5	GO:2000685	mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
1.4	6.9	GO:0048539	bone marrow development(GO:0048539)
1.3	3.8	GO:0033241	regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.1	3.2	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
1.0	2.9	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.0	2.9	GO:2000364	response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.8	3.9	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.8	2.3	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.7	7.7	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.7	4.2	GO:0090131	mesenchyme migration(GO:0090131)
0.7	5.5	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6	16.9	GO:0031639	plasminogen activation(GO:0031639)
0.6	2.5	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.6	1.8	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.5	9.9	GO:0007021	tubulin complex assembly(GO:0007021)
0.5	2.7	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.5	3.7	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.5	10.5	GO:0032060	bleb assembly(GO:0032060)
0.5	2.1	GO:0032972	diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.5	6.5	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.5	2.4	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.5	5.0	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.4	2.8	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4	1.2	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.4	1.1	GO:0097359	UDP-glucosylation(GO:0097359)
0.4	1.1	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4	4.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.3	1.0	GO:1905064	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) phenotypic switching(GO:0036166) negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of phenotypic switching(GO:1900239) negative regulation of vascular smooth muscle cell differentiation(GO:1905064) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.3	1.3	GO:0035995	detection of muscle stretch(GO:0035995)
0.3	1.5	GO:1904141	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.3	0.8	GO:1990523	bone regeneration(GO:1990523)
0.3	2.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3	0.8	GO:0006258	UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.2	1.0	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.2	3.4	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	3.6	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.2	0.8	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.2	2.8	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.2	1.3	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2	1.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2	2.2	GO:0015074	DNA integration(GO:0015074)
0.2	3.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	0.5	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2	0.7	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.2	0.5	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2	0.5	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2	0.6	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.2	3.1	GO:0006853	carnitine shuttle(GO:0006853)
0.1	2.8	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	2.4	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1	1.4	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	3.5	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.1	2.6	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1	1.2	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.3	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1	0.8	GO:0045007	depurination(GO:0045007)
0.1	7.9	GO:0030574	collagen catabolic process(GO:0030574)
0.1	14.9	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	0.6	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.1	1.4	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.4	GO:0099640	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) axo-dendritic protein transport(GO:0099640)
0.1	0.5	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.7	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	0.4	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.9	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.6	GO:0099563	modification of synaptic structure(GO:0099563)
0.1	1.0	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.4	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.2	GO:0009407	toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1	0.4	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.3	GO:2000320	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1	0.7	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.1	0.3	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1	0.7	GO:0019388	galactose catabolic process(GO:0019388)
0.1	1.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	2.1	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.1	0.6	GO:0007160	cell-matrix adhesion(GO:0007160)
0.1	6.4	GO:0030282	bone mineralization(GO:0030282)
0.1	2.6	GO:0050819	negative regulation of coagulation(GO:0050819)
0.1	0.5	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.3	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.4	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	1.1	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.9	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.6	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.5	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	1.9	GO:0048512	circadian behavior(GO:0048512)
0.0	0.5	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	2.0	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.2	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	1.5	GO:0048747	muscle fiber development(GO:0048747)
0.0	1.3	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.3	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	1.2	GO:0060548	negative regulation of cell death(GO:0060548)
0.0	3.5	GO:0043542	endothelial cell migration(GO:0043542)
0.0	1.9	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.6	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.2	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.7	GO:0043276	anoikis(GO:0043276)
0.0	0.3	GO:0001711	endodermal cell fate commitment(GO:0001711)
0.0	0.6	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.1	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.9	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.3	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0	0.6	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	2.2	GO:0010977	negative regulation of neuron projection development(GO:0010977)
0.0	2.2	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	1.5	GO:1900034	regulation of cellular response to heat(GO:1900034)
0.0	0.6	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.3	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.6	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.3	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	1.3	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.0	GO:0048009	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	1.2	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	1.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	2.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	4.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	8.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2	2.7	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2	15.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	7.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	7.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	3.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	0.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	0.9	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.0	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	0.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.8	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.1	1.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	2.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	1.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.6	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	3.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	2.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.9	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.6	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.8	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.4	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.6	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	1.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	2.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.4	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.5	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	5.9	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	1.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.1	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.8	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.0	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.5	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.7	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	3.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	0.8	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	1.8	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	1.2	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	1.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.6	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	3.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.8	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.6	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.7	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.7	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.5	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.9	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	15.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7	7.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5	10.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	1.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	7.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	7.8	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3	5.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.3	4.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	4.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	5.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	5.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	5.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	9.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	4.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	4.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.2	5.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	3.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	4.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	3.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	3.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	1.6	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	1.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	1.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	4.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2	1.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	0.5	REACTOME LAGGING STRAND SYNTHESIS	Genes involved in Lagging Strand Synthesis
0.1	2.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	3.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	0.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	0.2	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	1.3	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	2.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	4.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	5.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	5.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	0.3	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	1.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	3.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	1.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.8	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	5.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	1.4	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	1.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	1.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.7	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.1	2.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	2.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	7.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	3.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	4.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	5.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	1.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	1.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	2.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	2.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	2.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	2.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	2.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	1.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	2.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	0.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	2.9	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	0.9	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.8	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.1	0.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	0.3	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	1.6	REACTOME SHC MEDIATED CASCADE	Genes involved in SHC-mediated cascade
0.1	1.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	1.0	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	1.7	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.1	0.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	4.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.9	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.0	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.7	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	1.5	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	1.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.5	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	3.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.8	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	3.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.6	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.8	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	4.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	1.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.8	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.6	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	2.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.3	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.8	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	3.5	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	6.5	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.9	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.1	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	1.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.0	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	13.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	3.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	3.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	5.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.8	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	3.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	2.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	1.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	11.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	4.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.6	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	1.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	0.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	5.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	0.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	1.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	1.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.8	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.5	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.8	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	1.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
2.1	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	3.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	0.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	5.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	1.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	5.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	0.7	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	0.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	0.4	ST GAQ PATHWAY	G alpha q Pathway
0.1	3.4	PID AURORA B PATHWAY	Aurora B signaling
0.1	1.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	1.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	6.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	3.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.9	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	1.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	1.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	2.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	1.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	2.8	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.9	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.9	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.5	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	4.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.2	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	1.0	PID E2F PATHWAY	E2F transcription factor network
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.0	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.3	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	14.6	GO:1904274	tricellular tight junction assembly(GO:1904274)
2.2	6.6	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
2.2	19.5	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
1.8	5.3	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.4	5.8	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
1.2	3.7	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.2	6.2	GO:0042100	B cell proliferation(GO:0042100)
1.2	7.4	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
1.2	4.9	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.2	3.5	GO:2000909	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.1	3.4	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.1	3.2	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.0	5.2	GO:1902896	terminal web assembly(GO:1902896)
1.0	5.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.0	5.9	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.9	4.3	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.9	5.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.8	2.5	GO:0030264	nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.8	3.3	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.8	3.3	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.8	2.4	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.8	6.2	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.8	2.3	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7	3.7	GO:0009440	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.7	1.4	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.7	1.3	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.6	2.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.6	1.9	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.6	3.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.6	1.8	GO:0071934	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.6	1.7	GO:0097026	dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
0.6	2.3	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.5	1.6	GO:1904897	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.5	4.3	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.5	0.5	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.5	1.6	GO:0009107	lipoate biosynthetic process(GO:0009107)
0.5	1.6	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.5	1.6	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.5	1.0	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.5	2.6	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.5	1.5	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5	1.5	GO:0060381	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
0.5	3.5	GO:0008218	bioluminescence(GO:0008218)
0.5	1.5	GO:0043105	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.5	0.5	GO:0002159	desmosome assembly(GO:0002159)
0.5	2.5	GO:0050957	equilibrioception(GO:0050957)
0.5	2.0	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5	2.4	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.5	1.5	GO:0046210	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.5	1.9	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.5	1.9	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.5	1.9	GO:0015808	L-alanine transport(GO:0015808)
0.5	0.5	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.5	1.4	GO:1902994	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.5	2.8	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.5	0.5	GO:0034250	positive regulation of cellular amide metabolic process(GO:0034250)
0.5	2.7	GO:0006021	inositol biosynthetic process(GO:0006021)
0.5	1.8	GO:0045399	response to molecule of fungal origin(GO:0002238) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.4	1.8	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.4	1.3	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.4	0.4	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115)
0.4	1.3	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4	1.3	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4	0.4	GO:0001302	replicative cell aging(GO:0001302)
0.4	1.3	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4	1.7	GO:0050712	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.4	1.3	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.4	2.9	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.4	3.8	GO:0051547	regulation of keratinocyte migration(GO:0051547)
0.4	1.3	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.4	2.1	GO:0003069	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.4	3.7	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4	2.1	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.4	2.0	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.4	1.2	GO:1902809	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.4	28.5	GO:0006910	phagocytosis, recognition(GO:0006910)
0.4	0.8	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.4	1.1	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.4	1.9	GO:0010587	miRNA catabolic process(GO:0010587)
0.4	5.3	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.4	1.5	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.4	1.1	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4	1.9	GO:1904073	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4	0.4	GO:0060697	positive regulation of phospholipid catabolic process(GO:0060697)
0.4	2.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.4	3.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.4	1.1	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.4	1.1	GO:1903413	cellular response to bile acid(GO:1903413)
0.4	3.6	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.4	1.1	GO:0044179	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.3	2.4	GO:1904044	response to aldosterone(GO:1904044)
0.3	2.1	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
0.3	3.1	GO:0006552	leucine catabolic process(GO:0006552)
0.3	0.7	GO:1902001	carnitine shuttle(GO:0006853) fatty acid transmembrane transport(GO:1902001) carnitine transmembrane transport(GO:1902603)
0.3	3.0	GO:0036376	sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3	1.7	GO:0042816	vitamin B6 metabolic process(GO:0042816)
0.3	1.3	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.3	1.0	GO:1904386	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.3	3.3	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.3	2.0	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.3	1.6	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3	1.6	GO:0048478	replication fork protection(GO:0048478)
0.3	1.3	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.3	2.5	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.3	1.9	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.3	0.3	GO:1904591	positive regulation of protein import into nucleus(GO:0042307) positive regulation of protein import(GO:1904591)
0.3	4.0	GO:0070327	thyroid hormone transport(GO:0070327)
0.3	1.2	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.3	1.2	GO:0003335	corneocyte development(GO:0003335)
0.3	1.2	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.3	0.9	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.3	0.9	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3	3.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.3	1.2	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3	3.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.3	1.2	GO:2000609	regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611)
0.3	1.2	GO:0015942	formate metabolic process(GO:0015942)
0.3	1.1	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3	3.2	GO:0035747	natural killer cell chemotaxis(GO:0035747)
0.3	5.7	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.3	0.9	GO:2000861	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.3	2.0	GO:1903764	regulation of potassium ion export(GO:1902302) regulation of potassium ion export across plasma membrane(GO:1903764)
0.3	0.8	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
0.3	0.8	GO:2000173	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.3	1.1	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.3	1.6	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.3	3.5	GO:0019388	galactose catabolic process(GO:0019388)
0.3	1.9	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.3	0.8	GO:1904351	negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.3	0.8	GO:0048627	myoblast development(GO:0048627)
0.3	1.1	GO:0006670	sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.3	0.3	GO:0032423	regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.3	1.1	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) negative regulation of sodium:proton antiporter activity(GO:0032416)
0.3	0.5	GO:0072709	cellular response to sorbitol(GO:0072709)
0.3	0.8	GO:0007260	tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509)
0.3	1.0	GO:1903719	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.3	1.3	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3	1.8	GO:0032445	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.3	0.5	GO:0043615	astrocyte cell migration(GO:0043615)
0.3	0.8	GO:0032474	otolith morphogenesis(GO:0032474)
0.3	0.8	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.3	1.3	GO:0061143	alveolar primary septum development(GO:0061143)
0.3	1.0	GO:0014028	notochord formation(GO:0014028)
0.3	1.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.3	0.8	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
0.3	1.0	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.3	0.5	GO:0098727	stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.2	0.2	GO:0046730	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.2	0.5	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2	1.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2	0.7	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.2	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.2	0.2	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
0.2	2.6	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.2	1.0	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.2	0.7	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.2	1.9	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.2	1.2	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2	2.3	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2	0.9	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.2	0.5	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.2	0.7	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.2	0.9	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
0.2	0.5	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.2	1.4	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.2	0.5	GO:2000417	negative regulation of eosinophil migration(GO:2000417)
0.2	2.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.2	0.7	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.2	0.7	GO:2000538	regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2	0.9	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.2	0.9	GO:1903436	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2	2.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.7	GO:0031133	regulation of axon diameter(GO:0031133)
0.2	1.3	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.2	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.2	4.6	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2	0.2	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2	2.4	GO:0000050	urea cycle(GO:0000050)
0.2	0.7	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.2	0.6	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2	0.9	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.2	1.1	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2	0.8	GO:0042126	nitrate metabolic process(GO:0042126)
0.2	0.4	GO:0071812	regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.2	0.6	GO:1904482	response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.2	0.4	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2	0.2	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2	0.2	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2	0.6	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.2	0.6	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.2	1.0	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.2	1.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2	0.8	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2	1.4	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.2	1.4	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.2	0.4	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.2	1.2	GO:0070560	protein secretion by platelet(GO:0070560)
0.2	1.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	1.0	GO:0048733	sebaceous gland development(GO:0048733)
0.2	0.6	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.2	1.4	GO:0034378	chylomicron assembly(GO:0034378)
0.2	0.6	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2	0.6	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2	1.6	GO:0006116	NADH oxidation(GO:0006116)
0.2	0.8	GO:0097021	lymphocyte migration into lymphoid organs(GO:0097021)
0.2	1.8	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.2	0.4	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.2	3.2	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2	0.4	GO:0016999	antibiotic metabolic process(GO:0016999)
0.2	0.2	GO:0061032	visceral serous pericardium development(GO:0061032)
0.2	0.6	GO:0044501	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2	1.4	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.2	1.4	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
0.2	1.0	GO:0030070	insulin processing(GO:0030070)
0.2	0.2	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2	1.0	GO:0044351	macropinocytosis(GO:0044351)
0.2	1.0	GO:1990834	response to odorant(GO:1990834)
0.2	1.2	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.2	1.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.2	1.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.2	0.4	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.2	1.1	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.2	0.7	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2	2.0	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2	1.3	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.2	0.6	GO:1902499	positive regulation of protein autoubiquitination(GO:1902499)
0.2	0.7	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.2	0.4	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.2	1.5	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.2	0.2	GO:0035821	modification of morphology or physiology of other organism(GO:0035821)
0.2	0.5	GO:0046680	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.2	1.1	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.2	1.8	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.2	0.7	GO:0003011	diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
0.2	0.2	GO:0060482	lobar bronchus development(GO:0060482)
0.2	0.7	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2	0.2	GO:0035963	cellular response to interleukin-13(GO:0035963)
0.2	0.2	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533)
0.2	0.9	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.2	1.4	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.2	0.3	GO:0014040	positive regulation of Schwann cell differentiation(GO:0014040)
0.2	1.4	GO:1900004	negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.2	1.9	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2	0.7	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.2	0.5	GO:0009750	response to fructose(GO:0009750)
0.2	6.6	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.2	0.5	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2	0.9	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.2	0.7	GO:0006408	snRNA export from nucleus(GO:0006408)
0.2	0.3	GO:1903896	positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.2	1.5	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	0.5	GO:1904404	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2	0.3	GO:0014805	smooth muscle adaptation(GO:0014805)
0.2	2.2	GO:0040016	embryonic cleavage(GO:0040016)
0.2	2.8	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.2	1.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.2	4.0	GO:0072539	T-helper 17 cell differentiation(GO:0072539)
0.2	1.3	GO:0055069	cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.2	0.7	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2	4.0	GO:0006337	nucleosome disassembly(GO:0006337)
0.2	0.5	GO:0043103	hypoxanthine salvage(GO:0043103)
0.2	1.8	GO:0033623	regulation of integrin activation(GO:0033623)
0.2	2.9	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.2	0.2	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.2	0.3	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.2	0.5	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2	0.5	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.2	0.3	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.2	0.6	GO:0002034	regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.2	2.1	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.2	0.2	GO:0044146	negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.2	0.8	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.6	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2	2.4	GO:0061436	establishment of skin barrier(GO:0061436)
0.2	2.4	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2	0.5	GO:0045976	negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2	0.5	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2	0.5	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.2	1.2	GO:0007140	male meiosis(GO:0007140)
0.2	0.8	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.2	0.3	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.2	0.9	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2	0.6	GO:0016240	autophagosome docking(GO:0016240)
0.2	2.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	3.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2	0.3	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.2	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.2	0.5	GO:2000489	regulation of hepatic stellate cell activation(GO:2000489) positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	0.9	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2	1.1	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.2	0.3	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.2	0.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.7	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	1.6	GO:0006020	inositol metabolic process(GO:0006020)
0.1	2.1	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.1	0.7	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.1	GO:0006165	nucleoside diphosphate phosphorylation(GO:0006165)
0.1	1.6	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.9	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.1	0.3	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.1	0.9	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.3	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.6	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	1.2	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	0.4	GO:0071422	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	1.4	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	1.6	GO:1902222	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.6	GO:0009386	translational attenuation(GO:0009386)
0.1	1.3	GO:0002360	T cell lineage commitment(GO:0002360)
0.1	0.9	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	0.4	GO:0031126	snoRNA 3'-end processing(GO:0031126)
0.1	0.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.9	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1	0.3	GO:0060017	parathyroid gland development(GO:0060017)
0.1	0.4	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.4	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1	0.1	GO:0018393	internal peptidyl-lysine acetylation(GO:0018393) peptidyl-lysine acetylation(GO:0018394)
0.1	0.7	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.4	GO:0002316	follicular B cell differentiation(GO:0002316)
0.1	0.4	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.1	0.4	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
0.1	0.4	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.1	0.8	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1	1.4	GO:0070673	response to interleukin-18(GO:0070673)
0.1	0.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.1	2.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.1	0.8	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	1.5	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	0.1	GO:0048296	regulation of isotype switching to IgA isotypes(GO:0048296)
0.1	0.5	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.1	0.3	GO:0044036	cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.1	0.1	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1	0.4	GO:0032223	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1	0.1	GO:1904798	regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.1	0.5	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1	0.9	GO:0070269	pyroptosis(GO:0070269)
0.1	0.5	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.1	0.7	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	0.5	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.4	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1	1.2	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1	0.1	GO:0051231	mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.1	0.3	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1	0.1	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.1	0.5	GO:0001757	somite specification(GO:0001757)
0.1	0.3	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	1.0	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	1.7	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.1	0.4	GO:1901998	toxin transport(GO:1901998)
0.1	0.1	GO:0010644	cell communication by electrical coupling(GO:0010644)
0.1	2.0	GO:0034063	stress granule assembly(GO:0034063)
0.1	2.0	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.1	0.4	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1	1.1	GO:0015868	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1	1.5	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.3	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.1	0.1	GO:0072366	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1	0.5	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.1	0.9	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	0.6	GO:0071233	cellular response to leucine(GO:0071233)
0.1	0.5	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.2	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	0.2	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.1	0.4	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.4	GO:0006591	ornithine metabolic process(GO:0006591)
0.1	4.8	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	0.5	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.5	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1	0.4	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	2.0	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.8	GO:0006102	isocitrate metabolic process(GO:0006102)
0.1	14.0	GO:0030183	B cell differentiation(GO:0030183)
0.1	0.4	GO:1902943	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.1	0.2	GO:1990418	response to insulin-like growth factor stimulus(GO:1990418)
0.1	2.2	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	0.9	GO:1990668	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.1	0.6	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1	0.8	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.1	GO:0009217	purine deoxyribonucleotide catabolic process(GO:0009155) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dATP catabolic process(GO:0046061)
0.1	1.5	GO:0045008	depyrimidination(GO:0045008)
0.1	2.5	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.1	6.7	GO:0045576	mast cell activation(GO:0045576)
0.1	0.3	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1	0.3	GO:0006041	glucosamine metabolic process(GO:0006041)
0.1	0.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.1	0.2	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.1	0.5	GO:1904448	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) positive regulation of prolactin secretion(GO:1902722) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1	0.9	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.1	0.4	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	2.1	GO:0051255	spindle midzone assembly(GO:0051255)
0.1	0.9	GO:0042908	xenobiotic transport(GO:0042908)
0.1	0.7	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.2	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.1	0.9	GO:0015886	heme transport(GO:0015886)
0.1	0.2	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	1.0	GO:0010663	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1	1.0	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.1	0.6	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.3	GO:0007518	myoblast fate determination(GO:0007518)
0.1	1.0	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.6	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1	1.5	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1	1.2	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1	0.4	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1	1.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.5	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.7	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	0.9	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.3	GO:1901994	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1	0.7	GO:0042426	choline catabolic process(GO:0042426)
0.1	0.4	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.6	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.6	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.8	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.2	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1	0.3	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1	0.5	GO:0035799	ureter maturation(GO:0035799)
0.1	0.7	GO:0015840	urea transport(GO:0015840)
0.1	1.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.7	GO:0040032	post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1	1.0	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.3	GO:0048539	bone marrow development(GO:0048539)
0.1	0.4	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.8	GO:0006449	regulation of translational termination(GO:0006449)
0.1	0.4	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.8	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1	0.1	GO:0051085	'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1	1.5	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.1	0.5	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	0.4	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.3	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	1.0	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	0.7	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	0.6	GO:0044211	CTP salvage(GO:0044211)
0.1	0.4	GO:0048817	negative regulation of hair follicle maturation(GO:0048817)
0.1	0.3	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	2.3	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.1	2.0	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	0.3	GO:0042256	mature ribosome assembly(GO:0042256)
0.1	1.2	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1	0.2	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.1	0.4	GO:0019086	late viral transcription(GO:0019086)
0.1	0.3	GO:0030101	natural killer cell activation(GO:0030101)
0.1	0.2	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.1	0.3	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1	0.8	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.1	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.1	0.2	GO:1903412	response to bile acid(GO:1903412)
0.1	0.8	GO:0015705	iodide transport(GO:0015705)
0.1	0.3	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1	0.7	GO:0042473	outer ear morphogenesis(GO:0042473)
0.1	0.3	GO:0072535	tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307)
0.1	0.3	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1	0.5	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.1	0.1	GO:0072174	metanephric tubule formation(GO:0072174)
0.1	0.4	GO:0090164	asymmetric Golgi ribbon formation(GO:0090164)
0.1	0.5	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.4	GO:0019346	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.1	0.9	GO:0006265	DNA topological change(GO:0006265)
0.1	0.5	GO:0019640	glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.1	1.7	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.3	GO:0034115	negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1	0.3	GO:2000822	regulation of fear response(GO:1903365) positive regulation of fear response(GO:1903367) regulation of behavioral fear response(GO:2000822) positive regulation of behavioral fear response(GO:2000987)
0.1	0.2	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	0.2	GO:1904526	regulation of microtubule binding(GO:1904526)
0.1	5.9	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	1.7	GO:0006379	mRNA cleavage(GO:0006379)
0.1	0.5	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.6	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.2	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1	0.2	GO:1901859	base-excision repair, DNA ligation(GO:0006288) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.1	0.2	GO:0032782	bile acid secretion(GO:0032782)
0.1	1.8	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1	0.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.3	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.3	GO:1990502	dense core granule maturation(GO:1990502)
0.1	1.1	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.1	0.3	GO:0009258	10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1	0.4	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	1.1	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.1	0.2	GO:0019230	proprioception(GO:0019230)
0.1	0.4	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	0.5	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.1	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.1	3.2	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	0.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	1.9	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.1	0.9	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	1.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	0.1	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.1	0.7	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.3	GO:0043335	protein unfolding(GO:0043335)
0.1	0.3	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.1	4.1	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	1.2	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.1	0.2	GO:0045006	DNA deamination(GO:0045006) DNA cytosine deamination(GO:0070383)
0.1	0.3	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	0.7	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.1	0.1	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.1	1.6	GO:0006968	cellular defense response(GO:0006968)
0.1	0.8	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.3	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514)
0.1	0.1	GO:1902159	regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1	0.7	GO:0048853	forebrain morphogenesis(GO:0048853)
0.1	0.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.1	0.2	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	0.2	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	1.3	GO:0031167	rRNA methylation(GO:0031167)
0.1	0.2	GO:0006086	acetyl-CoA biosynthetic process(GO:0006085) acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	1.4	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.3	GO:1903236	regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1	0.2	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1	3.1	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1	0.2	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
0.1	0.6	GO:2001225	regulation of chloride transport(GO:2001225)
0.1	0.6	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	0.3	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.1	0.5	GO:0043316	cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
0.1	0.2	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1	0.2	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1	0.1	GO:0003220	left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.1	0.6	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	1.7	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1	2.6	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	1.1	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	1.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	1.1	GO:0045730	respiratory burst(GO:0045730)
0.1	1.0	GO:0005513	detection of calcium ion(GO:0005513)
0.1	0.5	GO:0009409	response to cold(GO:0009409)
0.1	0.9	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.1	2.5	GO:0051932	synaptic transmission, GABAergic(GO:0051932)
0.1	2.6	GO:0006270	DNA replication initiation(GO:0006270)
0.1	0.5	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.2	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.3	GO:0098838	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1	0.2	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.1	0.2	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.1	1.1	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1	0.3	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.1	0.2	GO:0003016	respiratory system process(GO:0003016)
0.1	0.1	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.1	0.3	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.4	GO:0021759	globus pallidus development(GO:0021759)
0.1	0.4	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.8	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.4	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.1	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.1	0.1	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.1	0.4	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.3	GO:0018377	protein myristoylation(GO:0018377)
0.1	0.7	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.1	0.1	GO:0060525	prostate glandular acinus development(GO:0060525)
0.1	0.2	GO:0097056	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	0.1	GO:0006711	estrogen catabolic process(GO:0006711)
0.1	0.4	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	0.7	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1	0.4	GO:0072643	interferon-gamma secretion(GO:0072643)
0.1	1.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.6	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.8	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.4	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.1	1.2	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1	0.4	GO:0042026	protein refolding(GO:0042026)
0.1	0.5	GO:0036438	maintenance of lens transparency(GO:0036438)
0.1	0.3	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.1	0.3	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1	0.6	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.8	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.1	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.1	0.7	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	1.0	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.1	0.4	GO:1903027	regulation of opsonization(GO:1903027)
0.1	0.1	GO:0002467	germinal center formation(GO:0002467)
0.1	0.3	GO:0010818	T cell chemotaxis(GO:0010818)
0.1	0.2	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1	1.3	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	0.4	GO:0030032	lamellipodium assembly(GO:0030032)
0.1	0.7	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.3	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1	0.7	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.1	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1	0.4	GO:0018065	protein-cofactor linkage(GO:0018065)
0.1	0.4	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1	0.5	GO:0070375	ERK5 cascade(GO:0070375)
0.1	1.9	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.2	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.3	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1	0.1	GO:0035864	response to potassium ion(GO:0035864)
0.1	0.3	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	0.4	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) regulation of locomotion involved in locomotory behavior(GO:0090325)
0.1	1.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.6	GO:1904872	regulation of telomerase RNA localization to Cajal body(GO:1904872)
0.1	0.2	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	4.6	GO:0070126	mitochondrial translational termination(GO:0070126)
0.1	0.2	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1	9.0	GO:0002431	Fc receptor mediated stimulatory signaling pathway(GO:0002431)
0.1	0.6	GO:0035082	axoneme assembly(GO:0035082)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.3	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.1	0.4	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.6	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.1	0.1	GO:0060019	radial glial cell differentiation(GO:0060019)
0.1	0.5	GO:0035092	sperm chromatin condensation(GO:0035092)
0.1	0.1	GO:0035935	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.1	0.8	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	0.7	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.1	1.9	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.1	0.1	GO:1901656	glycoside transport(GO:1901656)
0.1	0.6	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.2	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.1	0.2	GO:0042789	mRNA transcription(GO:0009299) mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	0.4	GO:0051026	chiasma assembly(GO:0051026)
0.1	0.2	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	0.2	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.2	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.1	0.2	GO:0048241	epinephrine transport(GO:0048241)
0.1	0.6	GO:0008340	determination of adult lifespan(GO:0008340)
0.1	0.8	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	0.1	GO:0042369	vitamin D catabolic process(GO:0042369)
0.1	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.1	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.2	GO:1902723	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1	0.2	GO:0000154	rRNA modification(GO:0000154)
0.1	0.1	GO:0034163	regulation of toll-like receptor 9 signaling pathway(GO:0034163) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.1	0.2	GO:0035865	cellular response to potassium ion(GO:0035865)
0.1	1.5	GO:0031055	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	4.8	GO:0042742	defense response to bacterium(GO:0042742)
0.1	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.2	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1	0.1	GO:1901317	regulation of sperm motility(GO:1901317)
0.1	0.2	GO:0060541	respiratory system development(GO:0060541)
0.1	0.8	GO:0046324	regulation of glucose import(GO:0046324)
0.1	0.5	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.1	2.4	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.1	0.3	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1	0.1	GO:0034502	protein localization to chromosome(GO:0034502)
0.1	0.2	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.1	0.2	GO:0031349	positive regulation of defense response(GO:0031349)
0.1	0.7	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	1.0	GO:0055078	sodium ion homeostasis(GO:0055078)
0.1	0.4	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.1	0.5	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.2	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.1	0.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.1	1.0	GO:0097186	amelogenesis(GO:0097186)
0.1	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.1	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	0.3	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.1	0.1	GO:0099525	presynaptic dense core granule exocytosis(GO:0099525)
0.1	0.3	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.1	0.9	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.1	0.2	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.1	0.4	GO:0031643	positive regulation of myelination(GO:0031643)
0.1	0.2	GO:0046629	gamma-delta T cell differentiation(GO:0042492) gamma-delta T cell activation(GO:0046629)
0.1	1.2	GO:0009648	photoperiodism(GO:0009648)
0.1	0.3	GO:0016128	phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.1	0.5	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.1	GO:0001522	pseudouridine synthesis(GO:0001522)
0.1	0.3	GO:1990035	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1	0.2	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1	0.4	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.2	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.1	0.7	GO:0015671	oxygen transport(GO:0015671)
0.1	0.2	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.2	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	0.6	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.1	0.2	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.1	0.1	GO:1903818	positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1	0.1	GO:0006581	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1	4.8	GO:1902476	chloride transmembrane transport(GO:1902476)
0.1	1.6	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.1	0.1	GO:0035811	negative regulation of urine volume(GO:0035811)
0.1	2.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	0.2	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1	0.6	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.1	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	0.2	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.1	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.6	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.3	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.1	0.2	GO:0035278	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1	1.0	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.1	0.7	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.1	0.5	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	0.4	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1	0.2	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1	0.3	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.1	0.4	GO:0007631	feeding behavior(GO:0007631)
0.1	0.8	GO:0071800	podosome assembly(GO:0071800)
0.1	0.3	GO:1901523	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1	0.7	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1	0.2	GO:1903298	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.1	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.2	GO:0018206	peptidyl-methionine modification(GO:0018206) N-terminal protein amino acid modification(GO:0031365)
0.0	0.2	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	3.7	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0051693	actin filament capping(GO:0051693)
0.0	0.1	GO:0009595	detection of biotic stimulus(GO:0009595)
0.0	0.2	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
0.0	0.1	GO:1990089	response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0	1.1	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.6	GO:0033875	nucleoside bisphosphate metabolic process(GO:0033865) ribonucleoside bisphosphate metabolic process(GO:0033875) purine nucleoside bisphosphate metabolic process(GO:0034032)
0.0	0.1	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.0	0.1	GO:0003430	growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.7	GO:1990118	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.2	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.3	GO:0060539	diaphragm development(GO:0060539)
0.0	0.4	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.4	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.2	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.2	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
0.0	0.9	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.3	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.3	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	1.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	1.2	GO:0032024	positive regulation of insulin secretion(GO:0032024)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.3	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.0	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.1	GO:1901355	response to rapamycin(GO:1901355)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.0	GO:0010266	response to vitamin B1(GO:0010266)
0.0	0.4	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.1	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.0	0.5	GO:0038092	nodal signaling pathway(GO:0038092)
0.0	0.4	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	0.8	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	4.1	GO:0070268	cornification(GO:0070268)
0.0	0.7	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.4	GO:0032264	IMP salvage(GO:0032264)
0.0	0.3	GO:0060430	lung saccule development(GO:0060430)
0.0	1.1	GO:0033198	response to ATP(GO:0033198)
0.0	0.1	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.0	0.2	GO:0015961	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0	0.4	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.9	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.3	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.2	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0	1.6	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0071105	response to interleukin-11(GO:0071105)
0.0	0.7	GO:0036499	PERK-mediated unfolded protein response(GO:0036499)
0.0	1.1	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.2	GO:0044380	protein localization to cytoskeleton(GO:0044380)
0.0	0.2	GO:0030220	platelet formation(GO:0030220)
0.0	0.2	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.3	GO:0001502	cartilage condensation(GO:0001502)
0.0	1.5	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	1.2	GO:0071346	cellular response to interferon-gamma(GO:0071346)
0.0	0.6	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:1902866	regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0	0.3	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.1	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.0	0.3	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	1.1	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.2	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.6	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.1	GO:0019056	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0	0.7	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0	1.0	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	3.3	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.3	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.3	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.6	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.0	0.3	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.0	0.3	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.3	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.3	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.9	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.1	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.1	GO:0050894	determination of affect(GO:0050894)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151) regulation of G0 to G1 transition(GO:0070316)
0.0	0.8	GO:0050715	positive regulation of cytokine secretion(GO:0050715)
0.0	0.6	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.2	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892) cerebral cortex GABAergic interneuron development(GO:0021894) GABAergic neuron differentiation(GO:0097154)
0.0	0.2	GO:0015874	norepinephrine transport(GO:0015874)
0.0	0.1	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.2	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.1	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.0	0.3	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0	0.3	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0	0.9	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.3	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.9	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.9	GO:1903859	regulation of dendrite extension(GO:1903859)
0.0	1.3	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0	2.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.3	GO:0010498	proteasomal protein catabolic process(GO:0010498)
0.0	0.1	GO:0072017	distal tubule development(GO:0072017)
0.0	0.3	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.4	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.3	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.6	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	1.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.2	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.0	0.5	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.6	GO:0002076	osteoblast development(GO:0002076)
0.0	0.4	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0	0.1	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.2	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.6	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0016259	selenocysteine metabolic process(GO:0016259) selenocysteine biosynthetic process(GO:0016260)
0.0	0.2	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.1	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.3	GO:0044784	metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
0.0	0.0	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.0	0.2	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.3	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.1	GO:0071548	response to dexamethasone(GO:0071548)
0.0	0.2	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.2	GO:0060260	regulation of transcription initiation from RNA polymerase II promoter(GO:0060260)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.4	GO:0070932	histone H3 deacetylation(GO:0070932)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0060179	male mating behavior(GO:0060179)
0.0	0.4	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.6	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:0048484	enteric nervous system development(GO:0048484)
0.0	0.1	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.4	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.3	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.0	0.6	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0	0.0	GO:0014041	regulation of neuron maturation(GO:0014041) negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:0042262	DNA protection(GO:0042262)
0.0	0.2	GO:1901796	regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.5	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.1	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.1	GO:0014904	myotube cell development(GO:0014904)
0.0	0.6	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.7	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	2.2	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.6	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	0.5	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.6	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.2	GO:0051962	positive regulation of nervous system development(GO:0051962)
0.0	0.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	1.1	GO:0061245	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	0.1	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.0	0.4	GO:0098760	interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.0	0.9	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.3	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0010840	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0	0.4	GO:0046686	response to cadmium ion(GO:0046686)
0.0	0.2	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.1	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	1.1	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.0	0.2	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0046368	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351) GDP-L-fucose metabolic process(GO:0046368)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.1	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	0.1	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.1	GO:0071315	cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0	0.1	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.3	GO:0043486	histone exchange(GO:0043486)
0.0	0.1	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.4	GO:0060292	long term synaptic depression(GO:0060292)
0.0	2.3	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.2	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.0	GO:0071971	extracellular exosome assembly(GO:0071971) regulation of extracellular exosome assembly(GO:1903551)
0.0	0.2	GO:0070193	synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.3	GO:1903363	negative regulation of cellular protein catabolic process(GO:1903363)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.6	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.0	GO:0051181	cofactor transport(GO:0051181)
0.0	0.0	GO:0006370	7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.1	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.1	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.2	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.0	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.2	GO:0032608	interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648)
0.0	0.8	GO:0007050	cell cycle arrest(GO:0007050)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.4	GO:0006094	gluconeogenesis(GO:0006094)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:1904589	regulation of protein import(GO:1904589)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.3	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0001906	cell killing(GO:0001906)
0.0	0.4	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.3	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.7	GO:0007602	phototransduction(GO:0007602)
0.0	0.0	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation(GO:0010998) evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.3	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.6	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.3	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.1	GO:0010771	negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.3	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0002088	lens development in camera-type eye(GO:0002088)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.2	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.0	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.0	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.0	GO:1901739	regulation of myoblast fusion(GO:1901739)
0.0	0.1	GO:0070875	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.1	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.0	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.0	0.4	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0070781	response to biotin(GO:0070781)
0.0	0.3	GO:0051782	negative regulation of cell division(GO:0051782)
0.0	0.1	GO:0044364	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0032479	regulation of type I interferon production(GO:0032479)
0.0	0.1	GO:0051806	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0032218	riboflavin transport(GO:0032218)
0.0	0.1	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0014898	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0	0.1	GO:0002429	immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.0	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0	0.0	GO:0002024	diet induced thermogenesis(GO:0002024)
0.0	0.3	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.1	GO:1901679	nucleotide transmembrane transport(GO:1901679)
0.0	0.1	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.0	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.0	GO:0002724	regulation of T cell cytokine production(GO:0002724)
0.0	0.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.1	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.0	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.0	GO:0046541	carbon dioxide transport(GO:0015670) saliva secretion(GO:0046541)
0.0	0.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0051769	nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.2	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.0	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.0	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.0	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.0	GO:0046463	triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0	0.1	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0048305	immunoglobulin secretion(GO:0048305)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.0	GO:0006183	GTP biosynthetic process(GO:0006183)
0.0	1.9	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.0	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.0	GO:0035315	hair cell differentiation(GO:0035315)
0.0	0.1	GO:0010606	regulation of cytoplasmic mRNA processing body assembly(GO:0010603) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	8.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2	3.0	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	9.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	3.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	0.6	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.6	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	2.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	2.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.6	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	0.8	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	2.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.3	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.9	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.8	2.5	GO:0090291	negative regulation of osteoclast proliferation(GO:0090291)
0.8	2.4	GO:0002894	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.7	4.5	GO:0090131	mesenchyme migration(GO:0090131)
0.7	2.2	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
0.7	2.9	GO:0031179	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.7	3.6	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.7	4.1	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7	2.0	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.6	2.6	GO:0072139	glomerular parietal epithelial cell differentiation(GO:0072139)
0.6	4.4	GO:0010269	response to selenium ion(GO:0010269)
0.6	1.9	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.6	2.4	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.6	1.7	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.6	3.4	GO:0001692	histamine metabolic process(GO:0001692)
0.6	1.7	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.6	1.7	GO:0006059	hexitol metabolic process(GO:0006059)
0.6	3.9	GO:0008218	bioluminescence(GO:0008218)
0.5	2.6	GO:0061107	seminal vesicle development(GO:0061107)
0.5	1.5	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.5	1.5	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.5	1.5	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.5	2.5	GO:0032571	response to vitamin K(GO:0032571)
0.4	1.3	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.4	1.2	GO:1904395	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.4	1.2	GO:0036071	N-glycan fucosylation(GO:0036071)
0.4	1.2	GO:0050923	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.4	3.4	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4	1.1	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.4	0.4	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.4	1.1	GO:0034255	nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.4	1.8	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.4	1.5	GO:1903288	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.4	3.6	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.4	0.7	GO:1903413	cellular response to bile acid(GO:1903413)
0.3	0.7	GO:0021966	corticospinal neuron axon guidance(GO:0021966)
0.3	1.4	GO:0061528	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3	1.0	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3	0.3	GO:1902994	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.3	3.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.3	0.3	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.3	0.3	GO:0030167	proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3	2.5	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3	0.9	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.3	1.8	GO:0006526	arginine biosynthetic process(GO:0006526)
0.3	0.9	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.3	0.3	GO:0097435	fibril organization(GO:0097435)
0.3	0.9	GO:2000864	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.3	1.4	GO:0035723	interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.3	1.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.3	1.1	GO:0002086	diaphragm contraction(GO:0002086)
0.3	0.5	GO:0000050	urea cycle(GO:0000050)
0.3	3.0	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.3	1.1	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.3	1.6	GO:0046113	nucleobase catabolic process(GO:0046113)
0.3	0.8	GO:0061461	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.3	3.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.3	1.6	GO:0034201	response to oleic acid(GO:0034201)
0.3	0.8	GO:0003285	septum secundum development(GO:0003285)
0.3	2.8	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.3	1.8	GO:0035624	receptor transactivation(GO:0035624)
0.3	2.8	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.2	1.5	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2	1.2	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2	0.7	GO:2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2	1.6	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.2	1.2	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2	0.2	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115)
0.2	0.7	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2	1.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	0.7	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.2	4.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.2	3.1	GO:0036376	sodium ion export from cell(GO:0036376)
0.2	0.7	GO:0043318	regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.2	1.1	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.2	0.4	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2	0.2	GO:0046688	response to copper ion(GO:0046688)
0.2	0.6	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2	0.6	GO:0006711	estrogen catabolic process(GO:0006711)
0.2	0.2	GO:0016139	glycoside catabolic process(GO:0016139)
0.2	0.6	GO:1900920	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.2	0.6	GO:0060437	lung growth(GO:0060437)
0.2	0.6	GO:2000724	nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.2	1.3	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.2	0.6	GO:1900073	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.2	0.6	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.2	0.8	GO:0030047	actin modification(GO:0030047)
0.2	0.6	GO:0006097	glyoxylate cycle(GO:0006097)
0.2	1.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.2	0.4	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
0.2	0.2	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.2	0.4	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.2	0.4	GO:1903978	regulation of microglial cell activation(GO:1903978)
0.2	0.6	GO:0072249	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2	0.8	GO:2001202	negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.2	0.6	GO:0003277	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2	2.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2	0.6	GO:0052027	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2	0.4	GO:0007412	axon target recognition(GO:0007412)
0.2	0.6	GO:0061760	antifungal innate immune response(GO:0061760)
0.2	0.6	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2	0.6	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.2	0.7	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.2	2.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2	1.8	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.2	0.6	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.2	0.4	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.2	0.5	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.2	0.5	GO:1903465	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.2	0.4	GO:0097646	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	3.9	GO:0006895	Golgi to endosome transport(GO:0006895)
0.2	0.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	1.6	GO:0051410	detoxification of nitrogen compound(GO:0051410)
0.2	0.7	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2	0.9	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.2	0.7	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.2	0.2	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.2	0.5	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.2	0.8	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.2	0.2	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.2	0.8	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.2	0.5	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.2	0.2	GO:0003162	atrioventricular node development(GO:0003162)
0.2	0.2	GO:0048371	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.2	0.8	GO:0061143	alveolar primary septum development(GO:0061143)
0.2	1.1	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2	2.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.2	0.5	GO:0043602	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.2	0.8	GO:0046952	ketone body catabolic process(GO:0046952)
0.2	0.6	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	0.6	GO:0036100	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.2	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.2	1.4	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.2	0.6	GO:0090107	regulation of high-density lipoprotein particle assembly(GO:0090107)
0.2	10.6	GO:0006910	phagocytosis, recognition(GO:0006910)
0.2	0.5	GO:0052314	serotonin biosynthetic process(GO:0042427) phytoalexin metabolic process(GO:0052314)
0.2	1.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.2	2.6	GO:0097242	beta-amyloid clearance(GO:0097242)
0.2	1.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.2	0.8	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	0.5	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	1.2	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	1.0	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.4	GO:0097359	UDP-glucosylation(GO:0097359)
0.1	0.1	GO:0060947	cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.1	0.4	GO:0099531	neurotransmitter secretion(GO:0007269) presynaptic process involved in chemical synaptic transmission(GO:0099531) signal release from synapse(GO:0099643)
0.1	0.3	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	1.9	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	1.1	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
0.1	1.3	GO:1903027	regulation of opsonization(GO:1903027)
0.1	0.8	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.3	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1	0.4	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	0.3	GO:0006710	androgen catabolic process(GO:0006710)
0.1	0.8	GO:1990504	dense core granule exocytosis(GO:1990504)
0.1	0.3	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1	0.1	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.1	1.4	GO:0070141	response to UV-A(GO:0070141)
0.1	0.7	GO:0046950	cellular ketone body metabolic process(GO:0046950)
0.1	0.4	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.1	0.5	GO:2000611	regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611)
0.1	0.5	GO:0035026	leading edge cell differentiation(GO:0035026)
0.1	0.1	GO:2000564	CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1	0.5	GO:0035900	plasma cell differentiation(GO:0002317) response to isolation stress(GO:0035900)
0.1	0.4	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.1	0.4	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.8	GO:0007386	compartment pattern specification(GO:0007386)
0.1	2.5	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.3	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	0.5	GO:0042361	menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1	0.9	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1	0.4	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1	0.4	GO:0019401	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1	0.4	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1	0.6	GO:0010952	positive regulation of peptidase activity(GO:0010952)
0.1	0.1	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.1	1.0	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.4	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1	0.4	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.1	0.2	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1	0.4	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1	1.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	1.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	1.6	GO:0009629	response to gravity(GO:0009629)
0.1	0.6	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.7	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	1.9	GO:0052695	cellular glucuronidation(GO:0052695)
0.1	0.4	GO:0003383	apical constriction(GO:0003383)
0.1	0.4	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.1	0.5	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1	0.6	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	0.6	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	0.3	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.3	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.1	0.1	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1	1.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.7	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.5	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	0.3	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1	0.4	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.6	GO:1905049	negative regulation of metallopeptidase activity(GO:1905049)
0.1	2.7	GO:0051923	sulfation(GO:0051923)
0.1	0.6	GO:0050955	thermoception(GO:0050955)
0.1	1.0	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.9	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	0.4	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1	0.2	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	0.5	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.1	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1	0.3	GO:0036512	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1	1.1	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	1.1	GO:0007144	female meiosis I(GO:0007144)
0.1	1.7	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.9	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.1	GO:0060197	cloacal septation(GO:0060197)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.3	GO:0006172	ADP biosynthetic process(GO:0006172)
0.1	0.1	GO:0072678	T cell migration(GO:0072678)
0.1	1.5	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.5	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	0.8	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.1	1.0	GO:0071493	cellular response to UV-B(GO:0071493)
0.1	0.3	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	0.3	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	1.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	2.6	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	1.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.4	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.3	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1	2.4	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1	0.3	GO:0014016	neuroblast differentiation(GO:0014016)
0.1	0.6	GO:0032328	alanine transport(GO:0032328)
0.1	1.5	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.1	0.2	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.1	0.5	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1	0.9	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.4	GO:0002155	thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1	0.1	GO:1904815	negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1	0.6	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.5	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.5	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	1.1	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	0.3	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	1.3	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	2.3	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.6	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.1	0.7	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1	0.5	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.3	GO:0014040	positive regulation of Schwann cell differentiation(GO:0014040)
0.1	0.4	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.1	1.9	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.1	0.1	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.1	1.0	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.1	0.6	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.1	0.1	GO:0018199	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.1	0.3	GO:0010876	lipid localization(GO:0010876)
0.1	0.5	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.1	0.3	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1	0.2	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.1	1.3	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	0.2	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	0.2	GO:0055072	iron ion homeostasis(GO:0055072)
0.1	0.2	GO:0035623	regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1	0.4	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.1	0.5	GO:0070417	cellular response to cold(GO:0070417)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.2	GO:0009812	flavonoid metabolic process(GO:0009812)
0.1	0.3	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	0.2	GO:1902564	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of neutrophil activation(GO:1902564)
0.1	0.8	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	0.2	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1	0.6	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1	0.6	GO:0048266	behavioral response to pain(GO:0048266)
0.1	0.7	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.1	0.5	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.1	0.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246) peptidyl-arginine omega-N-methylation(GO:0035247)
0.1	1.8	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	4.6	GO:0006953	acute-phase response(GO:0006953)
0.1	0.1	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.1	0.2	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1	4.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.4	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.2	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.1	1.0	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.1	0.4	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.1	0.4	GO:0071105	response to interleukin-11(GO:0071105)
0.1	0.1	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
0.1	0.4	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
0.1	0.8	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.4	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1	0.4	GO:0048793	pronephros development(GO:0048793)
0.1	0.4	GO:0070560	protein secretion by platelet(GO:0070560)
0.1	0.1	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.1	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.1	1.1	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1	0.5	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1	5.5	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.1	GO:0071287	cellular response to manganese ion(GO:0071287)
0.1	0.3	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.1	1.0	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	0.5	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.1	0.5	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.1	0.6	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.9	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.1	0.2	GO:0060157	urinary bladder development(GO:0060157)
0.1	0.2	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1	0.7	GO:0060174	limb bud formation(GO:0060174)
0.1	0.2	GO:1901899	positive regulation of relaxation of cardiac muscle(GO:1901899)
0.1	0.1	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.1	GO:0043385	mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1	0.6	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.1	GO:0006258	UDP-glucose catabolic process(GO:0006258)
0.1	2.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1	0.2	GO:0071529	cementum mineralization(GO:0071529)
0.1	0.2	GO:0070370	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1	0.3	GO:0002265	astrocyte activation involved in immune response(GO:0002265) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.1	0.5	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
0.1	0.5	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.3	GO:2000501	regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.3	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.1	1.4	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1	0.6	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.6	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.1	0.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.4	GO:0046208	spermine catabolic process(GO:0046208)
0.1	0.3	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1	0.1	GO:0050912	detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.1	0.2	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.1	0.2	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.1	0.9	GO:0099515	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1	0.4	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.1	0.1	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1	1.5	GO:0006855	drug transmembrane transport(GO:0006855)
0.1	0.1	GO:0071902	positive regulation of protein serine/threonine kinase activity(GO:0071902)
0.1	0.2	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	0.2	GO:0044375	regulation of peroxisome size(GO:0044375)
0.1	0.2	GO:0007518	myoblast fate determination(GO:0007518)
0.1	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.1	GO:0006382	adenosine to inosine editing(GO:0006382)
0.1	0.2	GO:1902806	regulation of cell cycle G1/S phase transition(GO:1902806)
0.1	0.1	GO:0016999	antibiotic metabolic process(GO:0016999)
0.1	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.1	0.4	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1	0.8	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.2	GO:0070874	negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.2	GO:0086098	angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.1	0.1	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1	1.0	GO:0035641	locomotory exploration behavior(GO:0035641)
0.1	0.2	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
0.1	1.3	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1	0.4	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.1	0.2	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.5	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.1	0.2	GO:1900368	transcription, RNA-templated(GO:0001172) regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369) positive regulation of protein localization to nucleolus(GO:1904751)
0.1	0.2	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.1	1.0	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	0.2	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1	0.3	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	1.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.1	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	1.6	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.1	0.3	GO:0051586	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.3	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.6	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.1	0.8	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.1	GO:0035456	response to interferon-beta(GO:0035456)
0.1	1.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1	0.1	GO:0051255	spindle midzone assembly(GO:0051255)
0.1	0.2	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.1	0.7	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.1	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.1	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	0.2	GO:2001023	regulation of response to drug(GO:2001023)
0.1	0.1	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.1	0.1	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.1	1.2	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.7	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.1	0.4	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.0	0.0	GO:1902022	lysine transport(GO:0015819) L-lysine transport(GO:1902022)
0.0	0.2	GO:0021699	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0	1.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.0	GO:0042742	defense response to bacterium(GO:0042742)
0.0	0.1	GO:0002692	negative regulation of cellular extravasation(GO:0002692)
0.0	0.1	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.2	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.0	0.3	GO:0008344	adult locomotory behavior(GO:0008344)
0.0	1.4	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0035089	establishment of apical/basal cell polarity(GO:0035089)
0.0	0.7	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.0	2.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.3	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.3	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	2.8	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.2	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.1	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.5	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.1	GO:0051917	regulation of fibrinolysis(GO:0051917)
0.0	0.3	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0	0.8	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.5	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0071233	cellular response to leucine(GO:0071233)
0.0	0.2	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.2	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0	0.3	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.7	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.3	GO:0097049	motor neuron apoptotic process(GO:0097049)
0.0	0.5	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.1	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.2	GO:0001501	skeletal system development(GO:0001501)
0.0	0.0	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.2	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.3	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0	0.1	GO:1904647	response to rotenone(GO:1904647)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.0	0.1	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) relaxation of skeletal muscle(GO:0090076)
0.0	0.1	GO:1901053	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0	0.0	GO:0034394	protein localization to cell surface(GO:0034394)
0.0	0.0	GO:0035803	egg coat formation(GO:0035803)
0.0	0.1	GO:0046100	hypoxanthine salvage(GO:0043103) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.4	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.6	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	0.1	GO:1990637	response to prolactin(GO:1990637)
0.0	0.2	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0	0.1	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0	0.2	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.2	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	1.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.5	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.2	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.6	GO:0051639	actin filament network formation(GO:0051639)
0.0	2.3	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.0	0.8	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.4	GO:1901071	glucosamine-containing compound metabolic process(GO:1901071)
0.0	1.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:1901224	positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.5	GO:0021534	cell proliferation in hindbrain(GO:0021534)
0.0	0.2	GO:1901096	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.0	0.2	GO:0048738	cardiac muscle tissue development(GO:0048738)
0.0	0.7	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.3	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.0	0.1	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.2	GO:0003190	atrioventricular valve formation(GO:0003190)
0.0	0.8	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.2	GO:0015811	L-cystine transport(GO:0015811)
0.0	1.4	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.3	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.8	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.0	GO:0034433	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0	0.2	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.4	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	1.0	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.3	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.2	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.2	GO:0003094	glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0	0.3	GO:1902416	positive regulation of mRNA binding(GO:1902416)
0.0	0.3	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.2	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.3	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.1	GO:0046717	glutamate secretion(GO:0014047) acid secretion(GO:0046717)
0.0	1.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0001825	blastocyst formation(GO:0001825)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.0	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.0	0.2	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0	0.3	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.1	GO:0010637	regulation of mitochondrial fusion(GO:0010635) negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.2	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.1	GO:0042426	choline catabolic process(GO:0042426)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:2001300	lipoxin metabolic process(GO:2001300)
0.0	0.1	GO:0071554	cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.1	GO:1902415	regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) regulation of mRNA binding(GO:1902415)
0.0	0.2	GO:0019323	pentose catabolic process(GO:0019323)
0.0	0.0	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.3	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.9	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.2	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	0.0	GO:0070432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.0	0.2	GO:1904180	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.0	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.6	GO:0033622	integrin activation(GO:0033622)
0.0	1.5	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.2	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:1904046	negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0	0.5	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.1	GO:0051037	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.5	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.4	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.8	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
0.0	0.5	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0035587	purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.2	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) regulation of oocyte maturation(GO:1900193) negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.1	GO:0061008	hepaticobiliary system development(GO:0061008)
0.0	0.2	GO:0009597	detection of virus(GO:0009597)
0.0	0.6	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.2	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.2	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.5	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.4	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	0.2	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.6	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.6	GO:0045730	respiratory burst(GO:0045730)
0.0	0.5	GO:0065005	protein-lipid complex assembly(GO:0065005)
0.0	0.1	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.6	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.2	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.3	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.2	GO:0086068	Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0	0.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0010044	response to aluminum ion(GO:0010044)
0.0	0.2	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.1	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.5	GO:0097186	amelogenesis(GO:0097186)
0.0	0.1	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0	0.1	GO:2000535	regulation of entry of bacterium into host cell(GO:2000535)
0.0	0.1	GO:0008204	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0	0.4	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0	0.2	GO:0036507	protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0006864	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0	1.4	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.5	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.1	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	2.3	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.1	GO:0090042	tubulin deacetylation(GO:0090042)
0.0	0.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	2.3	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.0	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.2	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0090260	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0	0.0	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258) neurofibrillary tangle assembly(GO:1902988)
0.0	0.2	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.0	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.4	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.4	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.4	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.0	GO:0014745	negative regulation of muscle adaptation(GO:0014745)
0.0	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.2	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.0	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.0	GO:0042713	sperm ejaculation(GO:0042713)
0.0	0.1	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.1	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0	0.3	GO:0051642	centrosome localization(GO:0051642)
0.0	0.6	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.0	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705) positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0	0.1	GO:0060149	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by RNA(GO:0060967)
0.0	0.1	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0	3.5	GO:0007565	female pregnancy(GO:0007565)
0.0	0.0	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell(GO:1904994)
0.0	0.1	GO:0060439	trachea morphogenesis(GO:0060439)
0.0	0.2	GO:0097499	protein localization to nonmotile primary cilium(GO:0097499)
0.0	0.1	GO:0019240	citrulline biosynthetic process(GO:0019240)
0.0	0.1	GO:0010634	positive regulation of epithelial cell migration(GO:0010634)
0.0	0.1	GO:0010665	regulation of cardiac muscle cell apoptotic process(GO:0010665)
0.0	0.0	GO:0035418	protein localization to synapse(GO:0035418)
0.0	0.3	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.1	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0	0.7	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	0.2	GO:1904896	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0	0.1	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0035549	positive regulation of interferon-beta secretion(GO:0035549) positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.1	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.1	GO:0001757	somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0	0.0	GO:1902622	regulation of neutrophil migration(GO:1902622)
0.0	2.9	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.4	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0031497	chromatin assembly(GO:0031497)
0.0	0.1	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.2	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.0	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0	0.0	GO:0036269	swimming behavior(GO:0036269)
0.0	0.1	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.0	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.3	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.0	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.2	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0	0.1	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
0.0	0.3	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.2	GO:0098743	cell aggregation(GO:0098743)
0.0	0.3	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.2	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0003147	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.0	0.0	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.0	0.1	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0	0.0	GO:0007618	mating(GO:0007618)
0.0	0.1	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.1	GO:0019563	alditol catabolic process(GO:0019405) glycerol catabolic process(GO:0019563)
0.0	0.3	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.3	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.4	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.5	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.2	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.6	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.2	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0002329	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.0	0.7	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	0.1	GO:0015893	drug transport(GO:0015893)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
0.0	0.5	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.1	GO:0070723	response to cholesterol(GO:0070723)
0.0	0.1	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:1904640	response to methionine(GO:1904640)
0.0	0.0	GO:0060142	regulation of syncytium formation by plasma membrane fusion(GO:0060142) positive regulation of syncytium formation by plasma membrane fusion(GO:0060143)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0042816	vitamin B6 metabolic process(GO:0042816)
0.0	0.6	GO:0046324	regulation of glucose import(GO:0046324)
0.0	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0	0.1	GO:0009582	detection of external stimulus(GO:0009581) detection of abiotic stimulus(GO:0009582)
0.0	0.1	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	0.2	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0042493	response to drug(GO:0042493)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.0	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.2	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0	0.0	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.2	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0006913	nucleocytoplasmic transport(GO:0006913)
0.0	0.2	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.2	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.0	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.0	0.2	GO:0040014	regulation of multicellular organism growth(GO:0040014)
0.0	0.1	GO:1900426	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) positive regulation of defense response to bacterium(GO:1900426)
0.0	0.1	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:1902001	fatty acid transmembrane transport(GO:1902001)
0.0	0.0	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.0	GO:0015960	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0	0.1	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.0	0.0	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.2	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.0	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0	0.4	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.2	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.1	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.1	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.1	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.3	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.0	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.1	GO:0046685	response to arsenic-containing substance(GO:0046685)
0.0	0.0	GO:0044805	late nucleophagy(GO:0044805)
0.0	0.0	GO:1903818	positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.0	GO:0030238	male sex determination(GO:0030238)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.2	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	1.4	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.2	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0098930	axonal transport(GO:0098930)
0.0	0.2	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.0	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.0	GO:2000192	negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0001771	immunological synapse formation(GO:0001771)
0.0	0.1	GO:0039694	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.2	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.1	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:2000177	regulation of neural precursor cell proliferation(GO:2000177)
0.0	0.1	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	1.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0	0.0	GO:0090235	regulation of metaphase plate congression(GO:0090235)
0.0	0.2	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	2.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	2.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	4.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	2.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	4.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	2.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	4.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.3	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	3.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.0	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.6	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	1.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.7	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	1.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	2.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	1.4	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.6	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	9.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.3	5.9	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.2	3.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	19.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	2.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.6	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.9	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	1.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	1.2	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	1.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.5	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	3.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	1.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.7	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	3.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	4.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.2	11.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	6.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	8.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	4.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	2.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	0.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	1.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	1.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	1.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	5.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	2.5	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	4.6	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.5	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	1.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	4.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	2.5	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	1.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	4.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	3.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	4.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	6.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	3.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	0.9	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.0	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	1.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	2.0	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	2.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	1.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.5	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.4	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	3.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	7.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	1.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	1.5	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.7	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.5	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.6	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	2.6	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	2.2	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	2.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.0	0.9	PID ATR PATHWAY	ATR signaling pathway
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.5	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	1.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	2.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.7	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.4	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	1.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	1.4	PID E2F PATHWAY	E2F transcription factor network
0.0	0.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.9	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
1.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.6	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.5	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.2	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.7	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	0.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.3	4.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	5.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	1.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	2.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	1.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.9	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	1.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	2.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.8	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0	1.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.0	0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.5	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	2.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	4.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	4.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	2.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	1.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	1.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.7	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.9	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.6	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	13.7	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.7	50.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	2.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	3.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	4.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	2.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	2.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	3.9	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	1.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	5.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.8	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	2.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.8	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	1.3	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.5	1.6	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.5	2.0	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5	1.4	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.3	1.0	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3	1.0	GO:0021763	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3	5.1	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.3	1.2	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.3	1.2	GO:0035720	signal transduction downstream of smoothened(GO:0007227) intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3	0.8	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.2	1.2	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.2	1.2	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.2	0.6	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.2	2.3	GO:0045176	apical protein localization(GO:0045176)
0.2	0.8	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.2	1.8	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
0.2	0.8	GO:0002572	pro-T cell differentiation(GO:0002572)
0.2	0.9	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2	0.9	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.2	0.5	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2	0.8	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2	1.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.2	1.4	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	3.6	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	2.0	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	0.7	GO:0006021	inositol biosynthetic process(GO:0006021)
0.1	0.8	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1	1.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	1.0	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.3	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	0.5	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1	0.5	GO:0006102	isocitrate metabolic process(GO:0006102)
0.1	1.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.1	0.1	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1	0.1	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1	0.6	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.6	GO:0042908	xenobiotic transport(GO:0042908)
0.1	1.1	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0	0.3	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.0	0.2	GO:0009386	translational attenuation(GO:0009386)
0.0	0.5	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.6	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	3.6	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.4	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.3	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:1901994	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	0.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.5	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.4	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.5	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.1	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860) specification of axis polarity(GO:0065001)
0.0	0.8	GO:0034329	cell junction assembly(GO:0034329)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	1.0	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.7	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.7	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.5	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.7	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.7	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.2	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0	0.7	GO:0033622	integrin activation(GO:0033622)
0.0	0.4	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	1.3	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.4	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.2	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0045007	DNA dealkylation involved in DNA repair(GO:0006307) depurination(GO:0045007)
0.0	0.2	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.3	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.3	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.7	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.0	GO:0007418	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0	0.1	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.0	0.2	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.7	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.3	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.0	0.3	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	0.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.1	GO:0035655	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) interleukin-18-mediated signaling pathway(GO:0035655)
0.0	0.6	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.1	GO:0060849	radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0	1.2	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.2	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	1.6	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	0.4	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.3	GO:0003016	respiratory system process(GO:0003016)
0.0	0.6	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.7	GO:0030818	negative regulation of cAMP biosynthetic process(GO:0030818)
0.0	0.1	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0	0.1	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
0.0	0.1	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.3	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.4	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.3	GO:0097178	ruffle assembly(GO:0097178)
0.0	0.5	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.4	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.6	2.5	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5	6.0	GO:0051525	NFAT protein binding(GO:0051525)
0.5	1.6	GO:0030350	iron-responsive element binding(GO:0030350)
0.5	2.6	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.5	2.6	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.4	3.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4	3.2	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.4	6.3	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3	1.7	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.3	0.7	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.3	1.2	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.3	0.9	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.3	2.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.3	1.7	GO:0030492	hemoglobin binding(GO:0030492)
0.3	1.1	GO:0043515	kinetochore binding(GO:0043515)
0.3	1.6	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.3	0.8	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3	1.0	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3	0.8	GO:0050421	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2	1.2	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.2	2.5	GO:0033592	RNA strand annealing activity(GO:0033592)
0.2	0.7	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.2	0.9	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.2	0.9	GO:0004074	biliverdin reductase activity(GO:0004074)
0.2	0.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.2	3.0	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2	0.5	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.2	0.5	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2	0.5	GO:0072510	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2	0.5	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.2	0.7	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.2	0.5	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2	0.5	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.4	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1	1.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.3	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.1	0.4	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1	0.8	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.4	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.4	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.5	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	0.4	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1	0.4	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	1.4	GO:0089720	caspase binding(GO:0089720)
0.1	1.7	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	0.7	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	1.4	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	0.4	GO:0030375	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.8	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	0.9	GO:0015288	porin activity(GO:0015288)
0.1	3.1	GO:0070034	telomerase RNA binding(GO:0070034)
0.1	0.4	GO:0031208	POZ domain binding(GO:0031208)
0.1	0.3	GO:0016731	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1	0.6	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	0.7	GO:0050733	RS domain binding(GO:0050733)
0.1	0.5	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.6	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.1	0.5	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.4	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.3	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.3	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	0.3	GO:0032427	GBD domain binding(GO:0032427)
0.1	0.4	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.1	0.5	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.1	1.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.3	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.9	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	1.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.4	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.4	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	1.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	1.3	GO:0030515	snoRNA binding(GO:0030515)
0.1	0.5	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.7	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.9	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	0.3	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.1	1.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.9	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.2	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.1	1.3	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	0.3	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.8	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.8	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.2	GO:0017089	glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.1	0.3	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.3	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	0.2	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0	1.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.3	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.7	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.4	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.3	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.2	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.5	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.4	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	1.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.4	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.5	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	1.0	GO:0005521	lamin binding(GO:0005521)
0.0	0.9	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	2.2	GO:0031491	nucleosome binding(GO:0031491)
0.0	1.0	GO:0005123	death receptor binding(GO:0005123)
0.0	0.4	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.9	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.7	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.6	GO:0070628	proteasome binding(GO:0070628)
0.0	0.5	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.1	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.0	0.8	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	1.6	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	1.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.4	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.4	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.6	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.5	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	1.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	3.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	1.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.6	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	1.1	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.1	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0	0.5	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.3	GO:0010181	FMN binding(GO:0010181)
0.0	0.3	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.8	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	1.5	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.9	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.8	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.1	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0043199	sulfate binding(GO:0043199)
0.0	0.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.7	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.6	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	2.8	GO:0061630	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.3	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.3	GO:0000149	SNARE binding(GO:0000149)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.0	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.0	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.8	5.6	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.5	1.5	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.4	2.1	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.4	1.2	GO:0036512	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.3	1.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.2	1.6	GO:0046485	ether lipid metabolic process(GO:0046485)
0.2	0.9	GO:0048539	bone marrow development(GO:0048539)
0.2	1.1	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.2	0.6	GO:2000230	negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2	0.8	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.6	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1	0.5	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1	0.9	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1	2.9	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	1.3	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.1	1.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.9	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.4	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.3	GO:1990523	bone regeneration(GO:1990523)
0.1	1.0	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.2	GO:0050787	antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) response to antineoplastic agent(GO:0097327)
0.1	1.0	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.2	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	0.3	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	0.2	GO:0043323	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0	0.2	GO:0006114	glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.0	0.2	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	2.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.2	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:1904383	response to sodium phosphate(GO:1904383)
0.0	0.2	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.0	0.4	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.6	GO:0030728	ovulation(GO:0030728)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.5	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.1	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.1	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.0	GO:0072642	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0	0.2	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.8	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.3	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.2	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.5	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.2	2.1	GO:0005577	fibrinogen complex(GO:0005577)
0.2	2.5	GO:0043073	germ cell nucleus(GO:0043073)
0.1	0.9	GO:0016013	syntrophin complex(GO:0016013)
0.1	8.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	0.4	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.8	GO:0030897	HOPS complex(GO:0030897)
0.1	1.2	GO:0071564	npBAF complex(GO:0071564)
0.0	3.8	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.5	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	1.3	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.0	0.5	GO:0010369	chromocenter(GO:0010369)
0.0	0.6	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.1	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	1.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.2	3.3	GO:0005833	hemoglobin complex(GO:0005833)
0.2	1.4	GO:0030061	mitochondrial crista(GO:0030061)
0.2	4.0	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	1.2	GO:0032437	cuticular plate(GO:0032437)
0.2	2.0	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	1.6	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	1.0	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	1.4	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.2	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0	0.3	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.9	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	1.1	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.3	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	3.0	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.5	GO:0005921	gap junction(GO:0005921)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	3.5	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.3	0.9	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.3	0.8	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.3	1.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	4.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2	1.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.2	2.2	GO:0008091	spectrin(GO:0008091)
0.1	4.1	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	0.7	GO:0061689	tricellular tight junction(GO:0061689)
0.1	1.4	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.0	GO:0042627	chylomicron(GO:0042627)
0.1	1.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.3	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	0.3	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.1	0.3	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.2	GO:0045160	myosin I complex(GO:0045160)
0.1	0.2	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	1.3	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.4	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.5	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:1903349	omegasome membrane(GO:1903349)
0.0	1.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	1.3	GO:0005605	basal lamina(GO:0005605)
0.0	0.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.6	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.8	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.4	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.3	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.4	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	4.0	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
0.0	0.4	GO:0033010	paranodal junction(GO:0033010)
0.0	0.1	GO:0072563	endothelial microparticle(GO:0072563)
0.0	0.1	GO:0031673	H zone(GO:0031673)
0.0	0.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.4	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.0	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.4	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.4	GO:0005883	neurofilament(GO:0005883)
0.0	0.7	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	1.8	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.6	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.5	GO:0031105	septin complex(GO:0031105)
0.0	2.2	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.6	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	1.0	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.8	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0032044	DSIF complex(GO:0032044)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.4	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.2	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.9	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.0	GO:0034680	integrin alpha1-beta1 complex(GO:0034665) integrin alpha8-beta1 complex(GO:0034678) integrin alpha10-beta1 complex(GO:0034680)
0.0	0.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.4	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.0	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	1.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.6	GO:0005604	basement membrane(GO:0005604)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	2.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.0	GO:0014802	terminal cisterna(GO:0014802)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.0	GO:0098827	endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0	0.0	GO:1990425	ryanodine receptor complex(GO:1990425)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.8	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.0	GO:0036398	TCR signalosome(GO:0036398)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	2.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	4.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	1.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	5.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.8	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.5	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.8	PID RHOA REG PATHWAY	Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	2.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	2.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	2.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	3.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.7	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.6	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	2.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.1	1.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0061617	MICOS complex(GO:0061617)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	0.1	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.0	1.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.8	GO:0005901	caveola(GO:0005901)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8	2.4	GO:0070699	type II activin receptor binding(GO:0070699)
0.7	2.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.6	3.9	GO:0034235	GPI anchor binding(GO:0034235)
0.6	1.9	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.6	6.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.5	2.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.5	10.7	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.5	35.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.5	1.4	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.4	1.5	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.4	1.1	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.4	2.9	GO:0048495	Roundabout binding(GO:0048495)
0.4	4.8	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.4	7.0	GO:0050786	RAGE receptor binding(GO:0050786)
0.3	1.6	GO:0017161	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3	3.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	1.6	GO:0038064	protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.3	5.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.3	1.2	GO:0097001	ceramide binding(GO:0097001)
0.3	1.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	3.4	GO:0045159	myosin II binding(GO:0045159)
0.3	1.3	GO:0030348	syntaxin-3 binding(GO:0030348)
0.2	1.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2	3.1	GO:0001968	fibronectin binding(GO:0001968)
0.2	19.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	1.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	1.2	GO:0005534	galactose binding(GO:0005534)
0.2	0.6	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.2	1.9	GO:0042731	PH domain binding(GO:0042731)
0.2	4.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.2	3.7	GO:0045504	dynein heavy chain binding(GO:0045504)
0.2	1.3	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2	0.5	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.2	1.8	GO:0046870	cadmium ion binding(GO:0046870)
0.2	4.6	GO:0070064	proline-rich region binding(GO:0070064)
0.2	0.8	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.2	1.9	GO:0036122	BMP binding(GO:0036122)
0.2	8.5	GO:0042169	SH2 domain binding(GO:0042169)
0.2	6.1	GO:0003785	actin monomer binding(GO:0003785)
0.2	8.5	GO:0005518	collagen binding(GO:0005518)
0.2	11.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	1.8	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	1.5	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	3.8	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.7	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.8	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	13.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.2	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.8	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1	1.9	GO:0016918	retinal binding(GO:0016918)
0.1	3.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.5	GO:0033906	protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.1	0.9	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	1.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.3	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	0.3	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	0.7	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	0.6	GO:1990254	keratin filament binding(GO:1990254)
0.1	2.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	0.6	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	1.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	0.5	GO:0031628	opioid receptor binding(GO:0031628)
0.1	11.1	GO:0005178	integrin binding(GO:0005178)
0.1	1.1	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.8	GO:0000150	recombinase activity(GO:0000150)
0.1	1.0	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	1.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	2.0	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.6	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.5	GO:0045499	chemorepellent activity(GO:0045499)
0.1	4.9	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1	0.5	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.4	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.2	GO:0000035	acyl binding(GO:0000035)
0.1	1.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.3	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.4	GO:0004955	prostaglandin receptor activity(GO:0004955) DBD domain binding(GO:0050692)
0.1	0.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.7	GO:0070679	store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1	2.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.3	GO:0004882	androgen receptor activity(GO:0004882)
0.0	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.5	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.6	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	2.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.3	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0	0.9	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	1.0	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.4	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	1.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	1.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.1	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0	0.5	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.0	3.7	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.9	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.5	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	1.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	1.4	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.0	4.3	GO:0004386	helicase activity(GO:0004386)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.3	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.4	GO:0016864	protein disulfide isomerase activity(GO:0003756) peptide disulfide oxidoreductase activity(GO:0015037) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.4	GO:0019956	chemokine binding(GO:0019956)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	4.6	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.0	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	5.2	GO:0003924	GTPase activity(GO:0003924)
0.0	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.9	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.0	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	1.0	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	1.4	GO:0005179	hormone activity(GO:0005179)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.2	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	1.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.4	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:1990357	terminal web(GO:1990357)
0.1	1.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	1.2	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	12.6	GO:0032038	myosin II heavy chain binding(GO:0032038)
1.1	3.3	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.5	1.6	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5	2.6	GO:0016403	dimethylargininase activity(GO:0016403)
0.5	5.6	GO:0031013	troponin I binding(GO:0031013)
0.4	1.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3	6.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.3	2.3	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.3	1.6	GO:0030348	syntaxin-3 binding(GO:0030348)
0.3	3.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	1.4	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.3	2.4	GO:0043426	MRF binding(GO:0043426)
0.3	1.0	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.3	2.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.2	1.9	GO:0004111	creatine kinase activity(GO:0004111)
0.2	1.7	GO:0070492	oligosaccharide binding(GO:0070492)
0.2	0.9	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2	1.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	1.6	GO:0071253	connexin binding(GO:0071253)
0.2	0.9	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	21.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	2.6	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.2	0.6	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.2	0.6	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.2	1.0	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.2	0.9	GO:0050436	microfibril binding(GO:0050436)
0.2	3.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.2	1.3	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.2	2.9	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	2.9	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.2	0.5	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2	1.0	GO:0005057	receptor signaling protein activity(GO:0005057)
0.2	0.5	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.2	0.6	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1	1.4	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1	1.0	GO:0050815	phosphoserine binding(GO:0050815)
0.1	4.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.4	GO:0051373	FATZ binding(GO:0051373)
0.1	0.5	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.6	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	1.4	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.5	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.5	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.4	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.3	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	0.8	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.3	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	1.2	GO:0031014	troponin T binding(GO:0031014)
0.1	0.3	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.1	0.5	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.3	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	0.4	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1	1.8	GO:0030506	ankyrin binding(GO:0030506)
0.1	1.0	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.3	GO:0047708	biotinidase activity(GO:0047708)
0.1	0.4	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.4	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	0.9	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.3	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.3	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.1	0.7	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	1.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.4	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	2.8	GO:0070888	E-box binding(GO:0070888)
0.1	0.3	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	0.1	GO:0015250	water channel activity(GO:0015250)
0.1	1.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1	0.6	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.1	1.3	GO:0070628	proteasome binding(GO:0070628)
0.1	0.3	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	0.4	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	0.2	GO:0070052	collagen V binding(GO:0070052)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	2.5	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	0.2	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	1.5	GO:0043236	laminin binding(GO:0043236)
0.1	0.2	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	2.2	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	0.2	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	1.0	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.1	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	2.8	GO:0030276	clathrin binding(GO:0030276)
0.0	1.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.5	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.8	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.5	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	1.0	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	1.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	2.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.4	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	5.5	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.0	1.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	2.3	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	6.2	GO:0044325	ion channel binding(GO:0044325)
0.0	0.2	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.0	0.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	2.8	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.7	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.6	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.4	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	1.5	GO:0030332	cyclin binding(GO:0030332)
0.0	2.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.3	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0070984	SET domain binding(GO:0070984)
0.0	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.6	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.2	GO:0043532	angiostatin binding(GO:0043532)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.7	GO:0043394	proteoglycan binding(GO:0043394)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.5	GO:0090079	translation repressor activity, nucleic acid binding(GO:0000900) translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.7	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.4	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.2	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.3	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.4	GO:0031005	filamin binding(GO:0031005)
0.0	0.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.9	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.3	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.7	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:1901474	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) azole transmembrane transporter activity(GO:1901474)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	1.5	GO:0030246	carbohydrate binding(GO:0030246)
0.0	1.2	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	1.0	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.7	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.3	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.3	GO:0008603	cAMP-dependent protein kinase inhibitor activity(GO:0004862) cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	2.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	2.2	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.9	GO:0017022	myosin binding(GO:0017022)
0.0	1.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.3	GO:0003924	GTPase activity(GO:0003924)
0.0	0.2	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.4	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.8	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.4	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.1	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	5.5	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.5	2.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.5	3.1	GO:0038064	collagen receptor activity(GO:0038064)
0.5	1.5	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.5	4.3	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5	1.4	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4	1.3	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.4	2.4	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4	1.5	GO:0002060	purine nucleobase binding(GO:0002060)
0.3	2.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	0.6	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	2.2	GO:0016015	morphogen activity(GO:0016015)
0.3	1.8	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3	0.9	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3	0.8	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3	2.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.7	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2	1.4	GO:1990254	keratin filament binding(GO:1990254)
0.2	1.4	GO:0043236	laminin binding(GO:0043236)
0.2	0.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.2	1.9	GO:0048495	Roundabout binding(GO:0048495)
0.2	3.2	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.6	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2	0.6	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	1.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2	0.7	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
0.2	1.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.2	0.9	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.2	0.5	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2	0.7	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.2	1.5	GO:0032051	clathrin light chain binding(GO:0032051)
0.2	0.6	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2	0.8	GO:0046870	cadmium ion binding(GO:0046870)
0.2	0.8	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.2	1.8	GO:0039706	co-receptor binding(GO:0039706)
0.2	1.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.4	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	0.6	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1	0.4	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	3.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	2.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	1.4	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.8	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.4	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	0.4	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.1	0.8	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.7	GO:0046979	TAP2 binding(GO:0046979)
0.1	0.6	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.5	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1	0.4	GO:0032093	SAM domain binding(GO:0032093)
0.1	2.5	GO:0005112	Notch binding(GO:0005112)
0.1	1.0	GO:0004064	arylesterase activity(GO:0004064)
0.1	1.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	0.3	GO:0070404	NADH binding(GO:0070404)
0.1	5.2	GO:0050699	WW domain binding(GO:0050699)
0.1	4.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.8	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	1.5	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.5	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1	1.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	0.7	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.1	0.4	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.4	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.3	GO:0004802	transketolase activity(GO:0004802)
0.1	0.2	GO:0034452	dynactin binding(GO:0034452)
0.1	0.4	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	0.3	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.1	0.6	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.3	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	1.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.4	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	1.0	GO:0042301	phosphate ion binding(GO:0042301)
0.1	0.4	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.1	0.7	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.1	1.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.7	GO:0005497	androgen binding(GO:0005497)
0.1	0.2	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	0.8	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.6	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.2	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	2.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	0.9	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.5	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	1.7	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	2.2	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	2.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.2	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1	0.4	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.3	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.1	0.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.5	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	1.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	3.4	GO:0019894	kinesin binding(GO:0019894)
0.1	0.7	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	0.2	GO:0047325	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1	0.5	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.2	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	0.9	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	1.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.4	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.2	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	0.5	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	1.2	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.8	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	0.4	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.7	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.6	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	0.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	5.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.3	GO:0017166	vinculin binding(GO:0017166)
0.1	0.2	GO:0042731	PH domain binding(GO:0042731)
0.1	0.5	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	2.8	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0004074	biliverdin reductase activity(GO:0004074)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.4	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.0	1.4	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.3	GO:0023025	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0080130	L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.2	GO:0016499	orexin receptor activity(GO:0016499)
0.0	1.2	GO:0031489	myosin V binding(GO:0031489)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.3	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.4	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.4	GO:0050544	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.4	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.4	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0052833	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.4	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.2	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.0	0.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	1.4	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.1	GO:0016672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	1.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.4	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.2	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	5.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.0	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	10.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.0	0.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.0	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.7	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0009975	adenylate cyclase activity(GO:0004016) guanylate cyclase activity(GO:0004383) cyclase activity(GO:0009975) phosphorus-oxygen lyase activity(GO:0016849)
0.0	0.2	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	0.3	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.0	0.2	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.5	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.2	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.0	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0	0.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	1.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.5	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.4	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	1.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.3	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.2	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	4.3	GO:0005178	integrin binding(GO:0005178)
0.0	1.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.5	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.6	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.2	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.7	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.7	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.1	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.2	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	1.0	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.1	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.2	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.0	1.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.0	1.1	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.7	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.0	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	1.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.4	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	1.0	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.8	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.0	GO:0004488	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0	0.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.9	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.4	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.0	0.3	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.0	0.2	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	1.0	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.2	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0047820	D-glutamate cyclase activity(GO:0047820)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.3	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:1904493	Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.3	GO:1902936	phosphatidylinositol bisphosphate binding(GO:1902936)
0.0	0.0	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.0	0.3	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.8	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	3.0	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.2	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.0	GO:0017129	triglyceride binding(GO:0017129)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.3	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.0	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.0	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.3	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.0	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0035240	dopamine binding(GO:0035240)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	2.4	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.0	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.0	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	12.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	3.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	2.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	3.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.8	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	1.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	2.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	3.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	2.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	1.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.4	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.5	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	2.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.6	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.7	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.7	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	42.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	8.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.4	7.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.4	13.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.4	35.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.4	2.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.3	9.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	21.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	8.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	5.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3	5.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	5.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	3.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	5.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3	5.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	4.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	5.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	4.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	7.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	4.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	11.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	1.6	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	4.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	3.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	0.6	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.2	3.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	5.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	2.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	5.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	4.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	4.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	3.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	2.9	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	7.0	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2	0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	3.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	4.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	2.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	3.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.7	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.3	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1	17.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	2.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	0.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	2.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	2.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	1.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	9.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	1.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	2.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	2.9	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	0.7	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	2.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	4.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	4.0	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.1	2.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	0.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	2.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	5.3	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	2.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	1.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	2.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1	0.3	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	2.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	8.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	0.7	REACTOME OPSINS	Genes involved in Opsins
0.1	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	0.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	3.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	1.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.6	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	2.0	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	1.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	3.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.9	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.5	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	2.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.5	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.6	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.4	2.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	2.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3	1.6	GO:1990254	keratin filament binding(GO:1990254)
0.2	1.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.2	0.7	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2	0.8	GO:0038025	reelin receptor activity(GO:0038025)
0.2	0.9	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2	1.0	GO:0046979	TAP2 binding(GO:0046979)
0.2	0.5	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	1.3	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.1	2.1	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.4	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1	0.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.4	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.4	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.7	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	4.9	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.5	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.4	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.1	1.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.1	13.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.7	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.2	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1	1.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.2	GO:0031177	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) phosphopantetheine binding(GO:0031177)
0.1	0.2	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.1	0.2	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.7	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.4	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	2.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.6	GO:0031419	cobalamin binding(GO:0031419)
0.1	1.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.2	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	0.3	GO:0008443	phosphofructokinase activity(GO:0008443)
0.1	0.2	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1	0.2	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.1	0.3	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.4	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.9	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.5	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.3	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0	2.5	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.6	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	1.5	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.6	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.3	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.4	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.0	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.4	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.5	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.0	0.6	GO:0051400	BH domain binding(GO:0051400)
0.0	0.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.5	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.6	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.4	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.8	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.7	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.2	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.1	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.5	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.4	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0070728	leucine binding(GO:0070728)
0.0	0.4	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.8	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.4	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.1	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.2	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0	0.4	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.4	GO:0035198	miRNA binding(GO:0035198)
0.0	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.1	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.0	0.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.8	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0	0.2	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.6	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.2	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.4	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.3	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0000992	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.0	0.1	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0	0.4	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.0	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.0	0.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.0	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	1.8	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.3	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.4	7.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	0.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	1.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.3	3.8	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.2	1.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	0.6	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.2	3.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	3.8	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.2	1.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2	2.5	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.2	4.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	5.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	3.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	2.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	5.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.6	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	0.1	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	1.8	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	2.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	3.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	5.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	2.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.0	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	0.2	REACTOME TRIF MEDIATED TLR3 SIGNALING	Genes involved in TRIF mediated TLR3 signaling
0.1	1.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	0.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	0.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	3.8	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	3.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	4.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	3.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	1.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.9	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	0.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	1.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	3.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	1.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	5.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.6	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.8	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	1.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	0.7	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	1.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.8	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.5	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1	0.2	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1	1.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	0.8	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	2.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	2.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.7	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.1	7.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.9	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.9	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	2.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	2.4	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	0.6	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.1	2.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	2.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	0.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	7.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.7	REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM	Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1	1.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	1.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	3.9	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	1.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	2.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.6	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.4	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.9	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.5	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.2	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	1.8	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	3.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	2.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.8	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	1.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	4.7	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.6	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.0	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	1.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	2.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.6	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
0.0	4.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.7	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.8	REACTOME TRANSCRIPTION COUPLED NER TC NER	Genes involved in Transcription-coupled NER (TC-NER)
0.0	1.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME NUCLEOTIDE EXCISION REPAIR	Genes involved in Nucleotide Excision Repair
0.0	0.8	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	1.3	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.5	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.5	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	1.5	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.1	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.1	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	0.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.0	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	3.9	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	0.9	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.9	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	0.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	1.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	1.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	1.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.7	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	1.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	2.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.2	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.6	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.8	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.7	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	2.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.5	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.0	0.2	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	4.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	6.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.4	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.6	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	0.9	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.3	6.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.3	1.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.2	3.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	0.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.2	0.6	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.2	5.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	3.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.2	2.6	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	3.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	0.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.2	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.2	4.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	3.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	2.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	3.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	5.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	2.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	2.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	1.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	1.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	3.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	3.3	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.1	5.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	1.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	0.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	0.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.8	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.8	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	1.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	4.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	2.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	2.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	1.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	2.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	2.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.5	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	1.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.9	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	4.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	0.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.6	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	0.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.1	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.1	1.5	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1	1.6	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	4.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	1.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.9	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.1	3.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	2.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	1.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.5	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1	0.6	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.0	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.2	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	1.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	0.9	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	1.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	2.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	1.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.7	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	1.0	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	4.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	4.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	12.9	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	2.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.6	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	1.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.0	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.8	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.6	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.2	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	2.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.9	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.7	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	1.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.5	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.4	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.6	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.5	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	1.0	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.0	0.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	1.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	2.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	3.2	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.3	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.1	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.0	0.1	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	1.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	1.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	2.9	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME PI 3K CASCADE	Genes involved in PI-3K cascade
0.0	0.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.3	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	1.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.4	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	1.7	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	2.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	2.6	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	2.8	PID ATM PATHWAY	ATM pathway
0.0	1.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	2.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.4	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	1.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	2.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	2.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	2.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	2.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.5	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.6	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.6	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.6	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID ATR PATHWAY	ATR signaling pathway
0.0	0.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.4	ST STAT3 PATHWAY	STAT3 Pathway
2.3	PID IL4 2PATHWAY	IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.8	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.9	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.7	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	1.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	1.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.7	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	3.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	6.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.8	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	5.8	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	2.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	1.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	3.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	7.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	5.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	0.7	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	5.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	0.7	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	1.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	2.6	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	0.3	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	1.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	7.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	1.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.5	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	2.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	1.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.4	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	3.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	1.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	1.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	1.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	5.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	4.6	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.5	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.3	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.8	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	7.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	2.5	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	2.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	2.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.1	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	10.2	GO:1990745	EARP complex(GO:1990745)
1.6	4.7	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
1.3	7.6	GO:0070435	Shc-EGFR complex(GO:0070435)
1.1	18.8	GO:0032059	bleb(GO:0032059)
1.0	6.9	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
1.0	3.9	GO:0070985	TFIIK complex(GO:0070985)
0.9	10.4	GO:0031595	nuclear proteasome complex(GO:0031595)
0.8	5.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.8	3.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.7	2.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.7	2.0	GO:0097441	basilar dendrite(GO:0097441)
0.7	2.0	GO:0071020	post-spliceosomal complex(GO:0071020)
0.6	6.9	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.6	6.7	GO:0097443	sorting endosome(GO:0097443)
0.6	2.2	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.6	5.0	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.5	4.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.5	0.5	GO:1990111	spermatoproteasome complex(GO:1990111)
0.5	2.0	GO:0032044	DSIF complex(GO:0032044)
0.5	4.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5	3.4	GO:0016272	prefoldin complex(GO:0016272)
0.5	4.3	GO:0034464	BBSome(GO:0034464)
0.5	1.4	GO:0030689	Noc complex(GO:0030689)
0.5	1.9	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.5	1.9	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.5	2.8	GO:0008537	proteasome activator complex(GO:0008537)
0.5	2.3	GO:0070847	core mediator complex(GO:0070847)
0.4	2.7	GO:0005688	U6 snRNP(GO:0005688)
0.4	2.1	GO:0071817	MMXD complex(GO:0071817)
0.4	4.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.4	4.0	GO:0000439	core TFIIH complex(GO:0000439)
0.4	2.8	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.4	2.0	GO:0032021	NELF complex(GO:0032021)
0.4	1.5	GO:0042587	glycogen granule(GO:0042587)
0.3	10.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.3	2.0	GO:0061689	tricellular tight junction(GO:0061689)
0.3	1.9	GO:0072589	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.3	3.7	GO:0030008	TRAPP complex(GO:0030008)
0.3	1.8	GO:1990130	Iml1 complex(GO:1990130)
0.3	3.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.3	0.9	GO:0018444	translation release factor complex(GO:0018444)
0.3	4.8	GO:0030914	STAGA complex(GO:0030914)
0.3	1.8	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3	0.9	GO:0005608	laminin-3 complex(GO:0005608)
0.3	6.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.3	0.8	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.3	0.8	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.3	2.4	GO:0072546	ER membrane protein complex(GO:0072546)
0.3	7.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.2	2.0	GO:0005683	U7 snRNP(GO:0005683)
0.2	2.7	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.2	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.2	1.7	GO:0000813	ESCRT I complex(GO:0000813)
0.2	1.7	GO:0005787	signal peptidase complex(GO:0005787)
0.2	5.9	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.2	1.2	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.2	1.6	GO:0031415	NatA complex(GO:0031415)
0.2	6.9	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2	3.0	GO:1990023	mitotic spindle midzone(GO:1990023)
0.2	0.9	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	0.2	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.2	0.9	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2	1.1	GO:0071986	Ragulator complex(GO:0071986)
0.2	2.5	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.2	0.6	GO:0034685	integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.2	0.6	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2	0.8	GO:0045160	myosin I complex(GO:0045160)
0.2	1.0	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2	1.6	GO:0071439	clathrin complex(GO:0071439)
0.2	0.6	GO:1902636	kinociliary basal body(GO:1902636)
0.2	0.6	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2	2.2	GO:0005642	annulate lamellae(GO:0005642)
0.2	3.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.2	0.6	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.2	3.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.2	2.0	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2	0.9	GO:0005602	complement component C1 complex(GO:0005602)
0.2	2.9	GO:0036452	ESCRT complex(GO:0036452)
0.2	2.8	GO:0042588	zymogen granule(GO:0042588)
0.2	0.7	GO:0055087	Ski complex(GO:0055087)
0.2	1.4	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2	1.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.2	0.6	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.2	3.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	0.5	GO:0070939	Dsl1p complex(GO:0070939)
0.2	2.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2	3.8	GO:0005685	U1 snRNP(GO:0005685)
0.1	0.4	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	4.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	0.6	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	1.6	GO:0022624	proteasome accessory complex(GO:0022624)
0.1	1.3	GO:0061574	ASAP complex(GO:0061574)
0.1	9.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.4	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1	1.6	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	1.7	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	4.5	GO:0016592	mediator complex(GO:0016592)
0.1	0.4	GO:0071159	NF-kappaB complex(GO:0071159)
0.1	2.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	0.8	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	2.1	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.1	0.8	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	0.9	GO:0097427	microtubule bundle(GO:0097427)
0.1	1.0	GO:0070552	BRISC complex(GO:0070552)
0.1	0.4	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.1	0.6	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	0.4	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	3.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.5	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	1.0	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.5	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	0.6	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	1.7	GO:0036020	endolysosome membrane(GO:0036020)
0.1	2.6	GO:0032040	small-subunit processome(GO:0032040)
0.1	0.6	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.1	1.8	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.1	1.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	1.2	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.5	GO:0000801	central element(GO:0000801)
0.1	1.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	1.2	GO:0000346	transcription export complex(GO:0000346)
0.1	2.0	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.4	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.9	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	0.5	GO:0097149	centralspindlin complex(GO:0097149)
0.1	2.8	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.4	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.5	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.1	0.6	GO:0000124	SAGA complex(GO:0000124)
0.1	1.8	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.1	1.3	GO:0031901	early endosome membrane(GO:0031901)
0.1	3.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	1.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.7	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.7	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1	0.3	GO:0036449	microtubule minus-end(GO:0036449)
0.1	1.4	GO:0005815	microtubule organizing center(GO:0005815)
0.1	0.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	1.2	GO:0036038	MKS complex(GO:0036038)
0.1	0.7	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.6	GO:0097165	nuclear stress granule(GO:0097165)
0.1	0.3	GO:0060091	kinocilium(GO:0060091)
0.1	3.2	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	1.7	GO:0030904	retromer complex(GO:0030904)
0.1	0.1	GO:0019034	viral replication complex(GO:0019034)
0.1	2.6	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	1.7	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1	0.2	GO:0097679	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1	0.3	GO:0070695	FHF complex(GO:0070695)
0.1	1.5	GO:0000812	Swr1 complex(GO:0000812)
0.1	0.5	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	0.7	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	0.3	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1	6.6	GO:0031227	intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1	0.2	GO:0016938	kinesin I complex(GO:0016938)
0.1	2.2	GO:0002102	podosome(GO:0002102)
0.1	4.0	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	3.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.3	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	3.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	6.1	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	0.5	GO:0097431	mitotic spindle pole(GO:0097431)
0.1	0.5	GO:0032797	SMN complex(GO:0032797)
0.1	7.4	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	1.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	1.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.1	0.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	3.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.2	GO:0000145	exocyst(GO:0000145)
0.1	4.9	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.3	GO:0042643	actomyosin, actin portion(GO:0042643)
0.1	0.2	GO:0044609	DBIRD complex(GO:0044609)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.2	GO:0014802	terminal cisterna(GO:0014802)
0.1	0.3	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.7	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.7	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	1.2	GO:0005861	troponin complex(GO:0005861)
0.1	1.7	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	1.0	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.4	GO:0090543	Flemming body(GO:0090543)
0.0	0.0	GO:0005687	U4 snRNP(GO:0005687)
0.0	1.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	1.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	1.9	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.6	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.9	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	6.8	GO:0030018	Z disc(GO:0030018)
0.0	7.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.2	GO:0001940	male pronucleus(GO:0001940)
0.0	1.7	GO:0016235	aggresome(GO:0016235)
0.0	4.8	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.4	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	1.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.4	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.8	GO:0030529	intracellular ribonucleoprotein complex(GO:0030529)
0.0	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.6	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.2	GO:0097651	phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0	0.1	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	1.0	GO:0015630	microtubule cytoskeleton(GO:0015630)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	4.4	GO:0001650	fibrillar center(GO:0001650)
0.0	0.7	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	2.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	8.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	3.5	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.8	GO:0005769	early endosome(GO:0005769)
0.0	0.4	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	10.5	GO:0005874	microtubule(GO:0005874)
0.0	0.4	GO:0031082	BLOC complex(GO:0031082)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.6	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.2	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.2	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.5	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.5	GO:0005859	muscle myosin complex(GO:0005859)
0.0	1.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.7	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	1.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	1.4	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.1	GO:0044427	chromosomal part(GO:0044427)
0.0	0.2	GO:0042583	chromaffin granule(GO:0042583)
0.0	2.6	GO:0005840	ribosome(GO:0005840)
0.0	1.1	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.6	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.5	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.3	GO:0005844	polysome(GO:0005844)
0.0	0.0	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0044438	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	0.2	GO:0045495	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	2.0	GO:0005794	Golgi apparatus(GO:0005794)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)
0.0	0.6	GO:0045095	keratin filament(GO:0045095)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.7	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.6	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.0	GO:0072563	endothelial microparticle(GO:0072563)
0.0	0.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	1.4	GO:0016605	PML body(GO:0016605)
0.0	10.4	GO:0005730	nucleolus(GO:0005730)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.7	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0045178	basal part of cell(GO:0045178)
0.0	1.4	GO:0043197	dendritic spine(GO:0043197)
0.0	1.5	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.5	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.8	GO:0005901	caveola(GO:0005901)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.7	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	2.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.3	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.0	GO:0005652	nuclear lamina(GO:0005652)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	0.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	2.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.9	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.7	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	2.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	1.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	2.1	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	2.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	2.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.6	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
1.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.4	GO:0005955	calcineurin complex(GO:0005955)
0.2	1.4	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	1.9	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.1	0.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	2.1	GO:0005916	fascia adherens(GO:0005916)
0.1	0.4	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	0.5	GO:1990745	EARP complex(GO:1990745)
0.1	0.5	GO:0070695	FHF complex(GO:0070695)
0.1	0.5	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	0.6	GO:0071203	WASH complex(GO:0071203)
0.1	0.9	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	1.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	0.2	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1	0.5	GO:0061617	MICOS complex(GO:0061617)
0.1	0.4	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	1.5	GO:0030673	axolemma(GO:0030673)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.9	GO:0005861	troponin complex(GO:0005861)
0.0	5.0	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.4	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.9	GO:0043218	compact myelin(GO:0043218)
0.0	0.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	1.0	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.5	GO:0031527	filopodium membrane(GO:0031527)
0.0	1.0	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	5.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	8.7	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.2	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	3.7	GO:0030018	Z disc(GO:0030018)
0.0	1.0	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0098793	presynapse(GO:0098793)
0.0	0.5	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.3	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.5	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0072589	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0	1.1	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0035976	AP1 complex(GO:0035976)
0.0	0.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	7.7	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
1.2	4.8	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.7	5.5	GO:0032010	phagolysosome(GO:0032010)
0.6	4.3	GO:0019815	B cell receptor complex(GO:0019815)
0.5	1.4	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.4	3.3	GO:0000322	storage vacuole(GO:0000322)
0.4	5.7	GO:0031209	SCAR complex(GO:0031209)
0.4	4.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.4	4.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.3	1.0	GO:0072563	endothelial microparticle(GO:0072563)
0.3	6.2	GO:0001891	phagocytic cup(GO:0001891)
0.3	3.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.3	0.8	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3	1.3	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.3	0.8	GO:0043291	RAVE complex(GO:0043291)
0.3	1.8	GO:0032584	growth cone membrane(GO:0032584)
0.2	5.6	GO:0000242	pericentriolar material(GO:0000242)
0.2	0.9	GO:0071001	U4/U6 snRNP(GO:0071001)
0.2	2.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	1.3	GO:0043196	varicosity(GO:0043196)
0.2	2.0	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.2	1.2	GO:0036021	endolysosome lumen(GO:0036021)
0.2	0.3	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.2	1.6	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.2	2.8	GO:0042101	T cell receptor complex(GO:0042101)
0.2	0.8	GO:0036398	TCR signalosome(GO:0036398)
0.1	0.4	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.1	0.4	GO:0061673	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.1	9.9	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	0.9	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.1	0.4	GO:0030125	clathrin vesicle coat(GO:0030125)
0.1	0.5	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.7	GO:0032807	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1	0.5	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	0.5	GO:0032044	DSIF complex(GO:0032044)
0.1	0.9	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	0.4	GO:0032449	CBM complex(GO:0032449)
0.1	1.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	1.2	GO:0097433	dense body(GO:0097433)
0.1	0.4	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	0.3	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	0.3	GO:0034455	t-UTP complex(GO:0034455)
0.1	0.3	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1	0.7	GO:0030870	Mre11 complex(GO:0030870)
0.1	1.2	GO:0030897	HOPS complex(GO:0030897)
0.1	1.3	GO:0008091	spectrin(GO:0008091)
0.1	0.3	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.4	GO:0089701	U2AF(GO:0089701)
0.1	0.4	GO:0032009	early phagosome(GO:0032009)
0.1	1.6	GO:0034709	methylosome(GO:0034709)
0.1	1.5	GO:0032059	bleb(GO:0032059)
0.1	0.8	GO:0097255	R2TP complex(GO:0097255)
0.1	0.4	GO:0031095	platelet dense tubular network(GO:0031094) platelet dense tubular network membrane(GO:0031095)
0.1	0.8	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.6	GO:0097361	CIA complex(GO:0097361)
0.1	0.6	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.5	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.1	0.5	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.3	GO:0033263	CORVET complex(GO:0033263)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.7	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	1.0	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	2.8	GO:0001772	immunological synapse(GO:0001772)
0.1	0.2	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	0.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	1.0	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.1	0.2	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	0.2	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.1	0.2	GO:1990031	pinceau fiber(GO:1990031)
0.1	0.5	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1	0.2	GO:0044609	DBIRD complex(GO:0044609)
0.1	1.9	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.3	GO:0042643	actomyosin, actin portion(GO:0042643)
0.1	0.5	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.8	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	2.4	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.3	GO:1902560	GMP reductase complex(GO:1902560)
0.0	0.6	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.3	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	0.7	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	6.0	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:1990393	3M complex(GO:1990393)
0.0	0.9	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.3	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.0	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	0.9	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.3	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	11.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.4	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.3	GO:0000502	proteasome complex(GO:0000502)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.6	GO:0000145	exocyst(GO:0000145)
0.0	0.8	GO:0035861	site of double-strand break(GO:0035861)
0.0	1.0	GO:0099738	cell cortex region(GO:0099738)
0.0	0.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0033391	chromatoid body(GO:0033391)
0.0	0.8	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.5	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.4	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	2.1	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.3	GO:0005686	U2 snRNP(GO:0005686)
0.0	4.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.6	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	2.4	GO:0005814	centriole(GO:0005814)
0.0	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.6	GO:0030673	axolemma(GO:0030673)
0.0	0.5	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	1.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.7	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.0	0.5	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0	0.9	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	2.1	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.1	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.2	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.4	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.6	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.6	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.6	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	1.0	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.3	GO:0016324	apical plasma membrane(GO:0016324)
0.0	2.4	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.5	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.3	GO:0005859	muscle myosin complex(GO:0005859)
0.0	1.3	GO:0030496	midbody(GO:0030496)
0.0	0.6	GO:0005871	kinesin complex(GO:0005871)
0.0	1.9	GO:0005741	mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	3.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.5	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1	1.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	1.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	1.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	21.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	7.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	6.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	7.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	10.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	2.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	3.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	2.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.7	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	9.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	1.9	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	1.2	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	2.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.8	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	3.1	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	2.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	2.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	13.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	2.9	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	2.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	3.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	3.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	0.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	0.6	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	2.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	3.8	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	1.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	1.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.7	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.5	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	1.8	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	0.6	GO:0019770	IgG receptor activity(GO:0019770)
0.1	1.0	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	4.5	GO:0070888	E-box binding(GO:0070888)
0.1	0.5	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1	0.3	GO:0061714	folic acid receptor activity(GO:0061714)
0.1	0.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.0	0.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	1.2	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.2	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.2	GO:0015639	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0	2.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	1.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0005174	CD40 receptor binding(GO:0005174)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0	0.1	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.0	0.3	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.9	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	2.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	1.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	8.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.7	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	3.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.8	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.3	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
1.3	12.7	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.7	2.2	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.7	4.8	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4	1.7	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3	1.0	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3	1.6	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.3	0.8	GO:1901297	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3	5.3	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.2	2.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2	1.4	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.2	1.4	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2	29.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	0.8	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.2	0.8	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	1.9	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2	1.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.2	1.2	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.2	1.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.2	0.5	GO:0021592	midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.2	0.5	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.2	0.5	GO:2000276	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2	1.1	GO:1904044	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.2	2.0	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.4	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	0.4	GO:0019474	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1	0.7	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.1	0.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.5	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.4	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.1	2.5	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	0.4	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.1	0.4	GO:2001303	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1	0.3	GO:0097254	renal tubular secretion(GO:0097254)
0.1	0.4	GO:0043335	protein unfolding(GO:0043335)
0.1	0.8	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1	1.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.1	0.7	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.1	1.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.3	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1	0.3	GO:1905229	cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.1	0.3	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.1	0.4	GO:0007296	vitellogenesis(GO:0007296)
0.1	1.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.2	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.6	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.3	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.1	0.3	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.9	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1	0.7	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.2	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.1	0.3	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.1	2.7	GO:0006735	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1	0.5	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.6	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.3	GO:0010731	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1	0.4	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.2	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.0	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.5	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.4	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	1.2	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.7	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	6.8	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.8	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.1	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.2	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0	1.0	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0	0.2	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.6	GO:0034063	stress granule assembly(GO:0034063)
0.0	6.2	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.2	GO:0002420	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.3	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.3	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	1.0	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.5	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.2	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.2	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	1.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.5	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.0	0.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.9	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	3.1	GO:0043149	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	0.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.2	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.1	GO:1902613	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0	0.2	GO:0035067	negative regulation of histone acetylation(GO:0035067)
0.0	0.6	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.2	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.9	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0	3.8	GO:0002250	adaptive immune response(GO:0002250)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.4	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.7	GO:0043966	histone H3 acetylation(GO:0043966)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	2.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	0.8	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	1.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.8	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	2.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.1	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.4	1.7	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.2	0.9	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2	0.8	GO:0016403	dimethylargininase activity(GO:0016403)
0.2	1.1	GO:0071253	connexin binding(GO:0071253)
0.1	0.9	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	1.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.4	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	1.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.7	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.3	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1	2.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.3	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1	0.4	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.8	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1	0.5	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	1.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	1.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.6	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0016749	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.0	2.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	1.0	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.3	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.0	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.6	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0	0.7	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.3	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.1	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0	0.3	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.5	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	1.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.5	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.7	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.2	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.0	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0	1.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.0	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	2.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	8.5	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.9	3.6	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.8	2.4	GO:0007412	axon target recognition(GO:0007412)
0.6	1.8	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5	1.6	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.5	6.1	GO:0001778	plasma membrane repair(GO:0001778)
0.4	1.9	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
0.2	1.1	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2	2.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2	1.3	GO:0089700	protein kinase D signaling(GO:0089700)
0.2	0.9	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.2	1.0	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2	0.5	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2	0.5	GO:0072275	branchiomeric skeletal muscle development(GO:0014707) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1	1.5	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.6	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.7	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.2	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	1.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	3.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.1	0.6	GO:0016584	nucleosome positioning(GO:0016584)
0.1	0.3	GO:0034334	adherens junction maintenance(GO:0034334)
0.0	0.2	GO:0035947	regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.0	1.5	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.3	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.2	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.3	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.8	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	1.0	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.3	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	1.4	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.4	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	1.8	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.0	0.1	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0	1.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.4	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	25.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	5.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	2.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	3.9	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	2.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.0	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.7	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	3.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	2.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.0	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	1.1	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	2.3	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.6	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	3.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.2	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	3.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.7	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.6	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	2.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	3.6	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	2.6	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	2.5	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.4	9.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	0.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.2	5.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	2.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.0	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	3.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	3.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	2.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	4.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	2.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	2.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	1.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.9	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.1	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	0.2	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	1.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	0.6	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	0.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	1.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	1.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	1.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	3.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.7	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.5	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	2.1	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.6	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	1.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	1.0	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.0	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.7	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	3.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	5.6	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.8	2.4	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.7	2.1	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.7	2.1	GO:0060166	olfactory pit development(GO:0060166)
0.7	2.0	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.6	5.5	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6	1.8	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.6	1.8	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.6	1.8	GO:0046521	sphingoid catabolic process(GO:0046521)
0.6	2.2	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.5	1.6	GO:0051796	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.5	4.3	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.5	1.4	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4	1.7	GO:0014028	notochord formation(GO:0014028)
0.4	1.2	GO:0033341	regulation of collagen binding(GO:0033341)
0.4	2.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.4	1.6	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4	2.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.4	1.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.4	1.9	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3	1.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3	1.0	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3	0.7	GO:0060214	endocardium formation(GO:0060214)
0.3	2.0	GO:0072719	cellular response to cisplatin(GO:0072719)
0.3	1.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3	1.0	GO:0070318	myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.3	1.3	GO:0042335	cuticle development(GO:0042335)
0.3	1.3	GO:0002545	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.3	1.0	GO:0046495	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.3	3.5	GO:0009414	response to water deprivation(GO:0009414)
0.3	1.9	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.3	1.2	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.3	0.9	GO:0042938	dipeptide transport(GO:0042938)
0.3	1.4	GO:0061146	Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.3	0.3	GO:0072240	DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.3	1.1	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.3	0.5	GO:0009886	post-embryonic morphogenesis(GO:0009886) post-embryonic eye morphogenesis(GO:0048050) post-embryonic organ morphogenesis(GO:0048563) post-embryonic organ development(GO:0048569)
0.3	0.8	GO:0042350	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.2	0.2	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.2	1.0	GO:0003409	optic cup structural organization(GO:0003409)
0.2	7.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	1.9	GO:0036486	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2	2.6	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.2	1.4	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.2	1.6	GO:1903232	melanosome assembly(GO:1903232)
0.2	0.2	GO:0009996	negative regulation of cell fate specification(GO:0009996)
0.2	0.7	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2	0.9	GO:0061290	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2	0.7	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2	0.7	GO:0032289	central nervous system myelin formation(GO:0032289)
0.2	1.8	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	1.5	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.2	0.7	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.2	0.6	GO:0032808	lacrimal gland development(GO:0032808)
0.2	1.7	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.2	0.6	GO:0060595	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.2	1.4	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2	1.2	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.2	2.3	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.2	0.8	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2	0.2	GO:0036109	alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.2	0.6	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.2	1.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	1.3	GO:0021683	cerebellar granular layer morphogenesis(GO:0021683)
0.2	0.9	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.2	1.4	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2	1.6	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2	1.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.2	0.5	GO:0048597	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2	0.2	GO:0097501	stress response to metal ion(GO:0097501)
0.2	0.5	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
0.2	0.7	GO:0030822	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2	1.2	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.2	0.5	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.2	0.5	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2	0.7	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2	1.3	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.2	0.2	GO:0032912	negative regulation of transforming growth factor beta2 production(GO:0032912)
0.2	1.4	GO:0051546	keratinocyte migration(GO:0051546)
0.2	0.5	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.2	0.6	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2	1.5	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.1	0.3	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.4	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1	0.4	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	1.2	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1	0.4	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1	0.4	GO:0045210	FasL biosynthetic process(GO:0045210)
0.1	0.1	GO:0010157	response to chlorate(GO:0010157)
0.1	1.5	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.1	0.6	GO:0036116	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1	0.5	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.1	0.7	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.4	GO:0035284	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	1.7	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	0.8	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	1.2	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.8	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1	0.6	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	1.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	3.8	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	1.1	GO:0045338	farnesyl diphosphate metabolic process(GO:0045338)
0.1	0.1	GO:1900223	positive regulation of beta-amyloid clearance(GO:1900223)
0.1	0.7	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1	0.2	GO:0021836	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.1	1.0	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.2	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1	1.3	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.1	0.2	GO:0006788	heme oxidation(GO:0006788)
0.1	1.6	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1	1.5	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.3	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.1	0.8	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1	3.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.1	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.1	0.3	GO:0044209	AMP salvage(GO:0044209)
0.1	0.1	GO:0097491	sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1	0.4	GO:0036510	trimming of terminal mannose on C branch(GO:0036510)
0.1	0.5	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1	0.6	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	0.9	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.1	0.4	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.2	GO:0032621	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.1	0.5	GO:0035926	chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1	0.8	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1	0.9	GO:0030091	protein repair(GO:0030091)
0.1	1.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.3	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1	1.1	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.1	5.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.4	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	2.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1	1.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	0.3	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.1	0.5	GO:1904693	midbrain morphogenesis(GO:1904693)
0.1	0.3	GO:0098904	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) regulation of AV node cell action potential(GO:0098904) regulation of bundle of His cell action potential(GO:0098905)
0.1	2.2	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	0.7	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	1.0	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	0.4	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.1	0.3	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1	0.2	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.1	0.3	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1	1.5	GO:0043616	keratinocyte proliferation(GO:0043616)
0.1	0.4	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.1	0.3	GO:2000777	endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1	0.9	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.7	GO:0015866	ADP transport(GO:0015866) ATP transport(GO:0015867) adenine nucleotide transport(GO:0051503)
0.1	0.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.1	0.3	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.1	0.3	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.1	0.5	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.6	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.4	GO:0061738	late endosomal microautophagy(GO:0061738)
0.1	0.1	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1	0.2	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.1	0.1	GO:0048073	regulation of eye pigmentation(GO:0048073)
0.1	0.2	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.5	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1	0.4	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.7	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.1	7.8	GO:0070268	cornification(GO:0070268)
0.1	0.5	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	1.1	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.1	0.7	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1	0.1	GO:0070585	protein localization to mitochondrion(GO:0070585)
0.1	1.1	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.6	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.1	0.3	GO:0019046	release from viral latency(GO:0019046)
0.1	0.6	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.5	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1	0.2	GO:0030035	microspike assembly(GO:0030035)
0.1	0.1	GO:1904636	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1	0.2	GO:0035329	hippo signaling(GO:0035329)
0.1	0.3	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1	0.2	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.1	0.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.4	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.3	GO:0070527	platelet aggregation(GO:0070527)
0.1	0.1	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	0.3	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.1	0.4	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	0.3	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	0.3	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	0.3	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.1	0.8	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	2.6	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.2	GO:0008355	olfactory learning(GO:0008355)
0.1	0.2	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.4	GO:0046618	drug export(GO:0046618)
0.1	0.4	GO:0072595	maintenance of protein localization in organelle(GO:0072595)
0.1	0.2	GO:0021633	optic nerve structural organization(GO:0021633)
0.1	0.3	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.1	0.2	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.1	1.1	GO:0015732	prostaglandin transport(GO:0015732)
0.1	1.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.1	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
0.1	0.2	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	1.1	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	1.4	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.1	0.6	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.1	0.1	GO:0035994	response to muscle stretch(GO:0035994) detection of muscle stretch(GO:0035995)
0.1	0.2	GO:0071048	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1	0.1	GO:0036093	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1	0.2	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1	0.4	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1	0.1	GO:0021759	globus pallidus development(GO:0021759)
0.1	0.7	GO:0009629	response to gravity(GO:0009629)
0.1	0.2	GO:1903362	regulation of cellular protein catabolic process(GO:1903362)
0.1	0.4	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1	0.1	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	0.6	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.1	0.2	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	1.7	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.1	0.9	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1	0.6	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	0.1	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1	0.2	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.1	0.1	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.1	0.2	GO:0042369	vitamin D catabolic process(GO:0042369)
0.1	0.2	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.7	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	1.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	0.3	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.3	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	0.2	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.1	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.3	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.3	GO:0002084	protein depalmitoylation(GO:0002084)
0.1	0.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.1	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0	0.0	GO:2001021	negative regulation of response to DNA damage stimulus(GO:2001021)
0.0	0.3	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.2	GO:0006542	glutamine biosynthetic process(GO:0006542)
0.0	0.0	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0	1.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.2	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0	0.3	GO:2000568	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) L-kynurenine metabolic process(GO:0097052)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.8	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.3	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.3	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.5	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.1	GO:0003218	cardiac left ventricle formation(GO:0003218)
0.0	0.7	GO:0003334	keratinocyte development(GO:0003334)
0.0	1.4	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.4	GO:0072319	synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
0.0	0.2	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.0	0.5	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.2	GO:0097338	response to clozapine(GO:0097338)
0.0	0.0	GO:0043449	cellular alkene metabolic process(GO:0043449)
0.0	0.2	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0	0.1	GO:1990164	histone H2A phosphorylation(GO:1990164)
0.0	0.6	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.3	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.0	0.1	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0	0.1	GO:0015698	inorganic anion transport(GO:0015698)
0.0	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.1	GO:0090045	positive regulation of deacetylase activity(GO:0090045)
0.0	1.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.4	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.4	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	0.1	GO:0051037	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0	0.1	GO:0099563	modification of synaptic structure(GO:0099563)
0.0	0.3	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:0071109	superior temporal gyrus development(GO:0071109)
0.0	0.6	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.3	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.4	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.6	GO:0032060	bleb assembly(GO:0032060)
0.0	0.5	GO:0006183	GTP biosynthetic process(GO:0006183)
0.0	0.2	GO:0016199	axon midline choice point recognition(GO:0016199) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0	1.0	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0	0.1	GO:0072014	proximal tubule development(GO:0072014)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0	0.1	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.0	0.0	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.0	0.2	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.3	GO:0045176	apical protein localization(GO:0045176)
0.0	0.2	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0	0.3	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0050856	regulation of T cell receptor signaling pathway(GO:0050856) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.0	0.8	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	0.2	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.2	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.5	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.2	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.4	GO:0051775	response to redox state(GO:0051775)
0.0	0.3	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.0	0.4	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.2	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0060796	regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0	0.1	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.3	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.6	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0	0.1	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0	0.1	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.8	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.5	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0	0.1	GO:2000825	regulation of androgen receptor activity(GO:2000823) positive regulation of androgen receptor activity(GO:2000825)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0035307	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.2	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0	0.1	GO:1900738	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.0	0.3	GO:0019068	virion assembly(GO:0019068)
0.0	0.1	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
0.0	0.1	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.9	GO:2000352	negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0	0.6	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.3	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.5	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.1	GO:0046104	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.2	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0	0.1	GO:1903960	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.0	0.2	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.0	0.1	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.0	0.4	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.3	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.8	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.1	GO:0071344	diphosphate metabolic process(GO:0071344)
0.0	0.4	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.3	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.6	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:0032526	response to retinoic acid(GO:0032526)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.1	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.0	0.1	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.3	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	0.2	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.6	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	0.2	GO:0050709	negative regulation of protein secretion(GO:0050709)
0.0	0.1	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0	0.4	GO:0046688	response to copper ion(GO:0046688)
0.0	0.1	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.0	0.1	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.0	0.1	GO:0046785	microtubule polymerization(GO:0046785)
0.0	0.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.2	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.0	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0	0.5	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0052027	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0	0.3	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	0.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:0003322	pancreatic A cell development(GO:0003322)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.1	GO:0001878	response to yeast(GO:0001878)
0.0	0.1	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:1905247	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0	0.1	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.1	GO:0034334	adherens junction maintenance(GO:0034334)
0.0	0.1	GO:0032418	lysosome localization(GO:0032418)
0.0	0.2	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.1	GO:0071283	cellular response to iron(III) ion(GO:0071283)
0.0	1.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0002884	type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.0	0.2	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.3	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.1	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.0	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0	0.0	GO:1990637	response to prolactin(GO:1990637)
0.0	0.1	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.0	0.2	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
0.0	0.4	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.2	GO:1901879	regulation of protein depolymerization(GO:1901879)
0.0	0.2	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.3	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.0	GO:2000374	regulation of oxygen metabolic process(GO:2000374)
0.0	0.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.3	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.1	GO:0001714	endodermal cell fate specification(GO:0001714)
0.0	0.2	GO:0045187	regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.0	GO:0008354	germ cell migration(GO:0008354)
0.0	0.3	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.5	GO:0046949	fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0	0.2	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	0.1	GO:0006954	inflammatory response(GO:0006954)
0.0	0.0	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0	0.2	GO:0036120	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.0	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.0	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.2	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.4	GO:0060384	innervation(GO:0060384)
0.0	0.0	GO:0038129	ERBB3 signaling pathway(GO:0038129)
0.0	0.2	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.0	0.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.1	GO:0010585	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0	0.0	GO:0070253	somatostatin secretion(GO:0070253)
0.0	0.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.2	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.1	GO:0090344	negative regulation of cell aging(GO:0090344)
0.0	0.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.0	1.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0	0.1	GO:1904738	vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752)
0.0	0.2	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.0	0.2	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0	0.0	GO:0030205	dermatan sulfate metabolic process(GO:0030205) dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0009635	response to herbicide(GO:0009635)
0.0	0.4	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.0	GO:0042700	luteinizing hormone signaling pathway(GO:0042700) cellular response to luteinizing hormone stimulus(GO:0071373)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.0	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.2	GO:1902221	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.1	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.0	GO:0050821	protein stabilization(GO:0050821)
0.0	0.1	GO:0071352	interleukin-2-mediated signaling pathway(GO:0038110) response to interleukin-2(GO:0070669) cellular response to interleukin-2(GO:0071352)
0.0	0.1	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.4	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.4	GO:0007032	endosome organization(GO:0007032)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.1	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.0	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0	0.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.8	GO:0006023	aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.1	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.6	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
1.3	9.2	GO:0097209	epidermal lamellar body(GO:0097209)
1.1	3.3	GO:0044393	microspike(GO:0044393)
1.0	3.0	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
1.0	23.2	GO:0005861	troponin complex(GO:0005861)
0.9	4.7	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.8	6.7	GO:0005610	laminin-5 complex(GO:0005610)
0.7	14.8	GO:0030056	hemidesmosome(GO:0030056)
0.7	5.8	GO:0098845	postsynaptic endosome(GO:0098845)
0.7	4.9	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.6	3.7	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.6	1.8	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.6	1.7	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.6	2.8	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.5	2.7	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.5	2.1	GO:0032301	MutSalpha complex(GO:0032301)
0.5	3.6	GO:0031415	NatA complex(GO:0031415)
0.5	2.0	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5	1.5	GO:0005667	transcription factor complex(GO:0005667)
0.5	2.4	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.5	6.2	GO:0097470	ribbon synapse(GO:0097470)
0.5	1.8	GO:0055087	Ski complex(GO:0055087)
0.4	1.8	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.4	6.1	GO:0005833	hemoglobin complex(GO:0005833)
0.4	1.3	GO:0072534	perineuronal net(GO:0072534)
0.4	2.6	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.4	0.9	GO:0097342	ripoptosome(GO:0097342)
0.4	2.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.4	6.0	GO:0008290	F-actin capping protein complex(GO:0008290)
0.4	0.8	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.4	1.2	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.4	2.3	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.4	6.6	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.4	0.8	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.4	2.6	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.4	1.1	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4	2.2	GO:1904724	tertiary granule lumen(GO:1904724)
0.4	0.4	GO:0032302	MutSbeta complex(GO:0032302)
0.4	1.8	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.4	1.8	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.4	0.4	GO:0030061	mitochondrial crista(GO:0030061)
0.3	7.0	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.3	9.3	GO:0002080	acrosomal membrane(GO:0002080)
0.3	2.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.3	2.0	GO:0005927	muscle tendon junction(GO:0005927)
0.3	2.3	GO:0042584	chromaffin granule membrane(GO:0042584)
0.3	4.0	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.3	1.6	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.3	1.3	GO:0044611	nuclear pore inner ring(GO:0044611)
0.3	2.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	1.9	GO:0051286	cell tip(GO:0051286)
0.3	6.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.3	0.9	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.3	1.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.3	1.5	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.3	1.5	GO:0042643	actomyosin, actin portion(GO:0042643)
0.3	5.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.3	0.3	GO:0030689	Noc complex(GO:0030689)
0.3	1.4	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.3	1.4	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.3	0.8	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.3	3.3	GO:0005642	annulate lamellae(GO:0005642)
0.3	1.1	GO:0043293	apoptosome(GO:0043293)
0.3	2.7	GO:0097255	R2TP complex(GO:0097255)
0.3	0.3	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.3	2.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	0.8	GO:0097441	basilar dendrite(GO:0097441)
0.3	0.3	GO:0030427	site of polarized growth(GO:0030427)
0.3	1.3	GO:0031905	early endosome lumen(GO:0031905)
0.3	2.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.3	1.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.3	2.9	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.3	1.0	GO:0000125	PCAF complex(GO:0000125)
0.3	2.0	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.3	2.8	GO:0070765	gamma-secretase complex(GO:0070765)
0.3	2.8	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.3	1.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	1.0	GO:0016600	flotillin complex(GO:0016600)
0.2	1.5	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.2	0.7	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.2	3.7	GO:0000124	SAGA complex(GO:0000124)
0.2	6.6	GO:0031143	pseudopodium(GO:0031143)
0.2	5.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	2.9	GO:0030008	TRAPP complex(GO:0030008)
0.2	2.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2	2.4	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2	7.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2	3.0	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.2	0.9	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.2	0.7	GO:0036128	CatSper complex(GO:0036128)
0.2	1.4	GO:0032444	activin responsive factor complex(GO:0032444)
0.2	1.1	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2	1.6	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.2	1.3	GO:0090661	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.2	0.7	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.2	0.9	GO:0030314	junctional membrane complex(GO:0030314)
0.2	1.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.2	1.1	GO:0071986	Ragulator complex(GO:0071986)
0.2	4.0	GO:0031932	TORC2 complex(GO:0031932)
0.2	0.7	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	0.9	GO:1990423	RZZ complex(GO:1990423)
0.2	17.2	GO:0034707	chloride channel complex(GO:0034707)
0.2	0.9	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	0.9	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.2	0.6	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.2	3.6	GO:0005922	connexon complex(GO:0005922)
0.2	1.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.2	2.5	GO:0043219	lateral loop(GO:0043219)
0.2	1.2	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.2	1.5	GO:0032593	insulin-responsive compartment(GO:0032593)
0.2	0.6	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	0.6	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.2	1.2	GO:0001939	female pronucleus(GO:0001939)
0.2	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.2	0.6	GO:0031970	organelle envelope lumen(GO:0031970)
0.2	3.8	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.2	0.2	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.2	3.3	GO:0032059	bleb(GO:0032059)
0.2	0.6	GO:0043291	RAVE complex(GO:0043291)
0.2	1.7	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2	1.0	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2	0.2	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.2	2.7	GO:0005883	neurofilament(GO:0005883)
0.2	2.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	4.0	GO:0097228	sperm principal piece(GO:0097228)
0.2	0.4	GO:0005652	nuclear lamina(GO:0005652)
0.2	1.3	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.2	5.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2	2.0	GO:0044666	MLL3/4 complex(GO:0044666)
0.2	0.5	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2	2.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	0.5	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2	0.9	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.2	1.4	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2	0.5	GO:0043159	acrosomal matrix(GO:0043159)
0.2	0.4	GO:0070557	PCNA-p21 complex(GO:0070557)
0.2	0.4	GO:0000779	condensed chromosome, centromeric region(GO:0000779)
0.2	1.6	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	0.9	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2	0.2	GO:0070187	telosome(GO:0070187)
0.2	7.0	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	0.7	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	0.7	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.2	0.5	GO:0016013	syntrophin complex(GO:0016013)
0.2	0.5	GO:0016938	kinesin I complex(GO:0016938)
0.2	0.5	GO:0019012	virion(GO:0019012) virion part(GO:0044423)
0.2	0.9	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.2	1.2	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.2	1.0	GO:0070545	PeBoW complex(GO:0070545)
0.2	1.0	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2	0.3	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.2	5.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	2.7	GO:0036020	endolysosome membrane(GO:0036020)
0.2	1.5	GO:0070652	HAUS complex(GO:0070652)
0.2	1.0	GO:0005688	U6 snRNP(GO:0005688)
0.2	4.6	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2	0.2	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.2	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.2	1.0	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.2	0.3	GO:0033186	CAF-1 complex(GO:0033186)
0.2	0.6	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.2	0.5	GO:0030904	retromer complex(GO:0030904)
0.2	1.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	1.7	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2	1.3	GO:0005818	astral microtubule(GO:0000235) aster(GO:0005818)
0.2	4.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2	0.6	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2	0.6	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2	1.1	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2	0.5	GO:0000785	chromatin(GO:0000785)
0.1	1.0	GO:0090543	Flemming body(GO:0090543)
0.1	6.5	GO:0001533	cornified envelope(GO:0001533)
0.1	0.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	0.6	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1	0.9	GO:0030914	STAGA complex(GO:0030914)
0.1	3.7	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	16.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	1.3	GO:0005955	calcineurin complex(GO:0005955)
0.1	2.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.7	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.8	GO:0045120	pronucleus(GO:0045120)
0.1	0.8	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.1	0.5	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	0.1	GO:0042587	glycogen granule(GO:0042587)
0.1	1.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.3	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	4.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	1.2	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	4.9	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	0.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	3.1	GO:0046930	pore complex(GO:0046930)
0.1	0.8	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	1.6	GO:0042555	MCM complex(GO:0042555)
0.1	2.3	GO:0036379	myofilament(GO:0036379)
0.1	0.1	GO:0044305	calyx of Held(GO:0044305)
0.1	2.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	0.6	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	2.0	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	0.4	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.4	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.1	1.0	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	1.2	GO:0097512	cardiac myofibril(GO:0097512)
0.1	1.0	GO:0042382	paraspeckles(GO:0042382)
0.1	1.6	GO:0005875	microtubule associated complex(GO:0005875)
0.1	0.1	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	0.6	GO:0000242	pericentriolar material(GO:0000242)
0.1	2.9	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.5	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.8	GO:0044327	dendritic spine head(GO:0044327)
0.1	0.1	GO:0030681	ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1	0.4	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
0.1	0.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	1.4	GO:0097431	mitotic spindle pole(GO:0097431)
0.1	0.5	GO:1990357	terminal web(GO:1990357)
0.1	0.8	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	10.9	GO:0005882	intermediate filament(GO:0005882)
0.1	5.7	GO:0001772	immunological synapse(GO:0001772)
0.1	0.8	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.6	GO:0035061	interchromatin granule(GO:0035061)
0.1	5.7	GO:0045171	intercellular bridge(GO:0045171)
0.1	1.6	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.3	GO:0070435	Shc-EGFR complex(GO:0070435)
0.1	1.3	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.3	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.1	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.1	1.0	GO:0044194	cytolytic granule(GO:0044194)
0.1	1.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.4	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1	0.8	GO:0033269	internode region of axon(GO:0033269)
0.1	1.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	1.8	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	1.1	GO:0033643	host cell part(GO:0033643)
0.1	3.8	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.3	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.1	3.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	1.0	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	2.2	GO:0002102	podosome(GO:0002102)
0.1	0.6	GO:0001740	Barr body(GO:0001740)
0.1	0.3	GO:0097440	apical dendrite(GO:0097440)
0.1	2.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	0.5	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.2	GO:0032156	septin cytoskeleton(GO:0032156)
0.1	0.9	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.9	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	1.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.2	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.1	2.5	GO:0030673	axolemma(GO:0030673)
0.1	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	1.0	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.3	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1	0.8	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.7	GO:0016272	prefoldin complex(GO:0016272)
0.1	1.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	1.2	GO:0005795	Golgi stack(GO:0005795)
0.1	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.3	GO:0031417	NatC complex(GO:0031417)
0.1	1.0	GO:0097433	dense body(GO:0097433)
0.1	2.7	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.5	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.1	0.1	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.4	GO:0030057	desmosome(GO:0030057)
0.1	2.7	GO:0043034	costamere(GO:0043034)
0.1	0.6	GO:0031298	replication fork protection complex(GO:0031298)
0.1	1.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.3	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.5	GO:0070852	cell body fiber(GO:0070852)
0.1	1.2	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1	0.3	GO:0044609	DBIRD complex(GO:0044609)
0.1	0.8	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.7	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	0.3	GO:1990769	proximal neuron projection(GO:1990769)
0.1	12.7	GO:0030426	growth cone(GO:0030426)
0.1	0.4	GO:0089701	U2AF(GO:0089701)
0.1	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.6	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.1	0.2	GO:1990635	proximal dendrite(GO:1990635)
0.1	4.3	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	0.2	GO:0005771	multivesicular body(GO:0005771)
0.1	1.0	GO:0000145	exocyst(GO:0000145)
0.1	0.6	GO:0042588	zymogen granule(GO:0042588)
0.1	5.2	GO:0043195	terminal bouton(GO:0043195)
0.1	1.5	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	1.1	GO:0071437	invadopodium(GO:0071437)
0.1	0.6	GO:0032389	MutLalpha complex(GO:0032389)
0.1	0.5	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.1	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.1	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.1	0.2	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.1	GO:0016342	catenin complex(GO:0016342)
0.1	0.3	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.1	0.8	GO:0005869	dynactin complex(GO:0005869)
0.1	0.2	GO:0036398	TCR signalosome(GO:0036398)
0.1	2.5	GO:0043198	dendritic shaft(GO:0043198)
0.1	0.5	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.4	GO:0035859	Seh1-associated complex(GO:0035859) Iml1 complex(GO:1990130)
0.1	1.9	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	0.5	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.1	GO:0044308	axonal spine(GO:0044308)
0.1	0.4	GO:0097386	glial cell projection(GO:0097386)
0.1	0.8	GO:0000815	ESCRT III complex(GO:0000815)
0.1	1.5	GO:0070069	cytochrome complex(GO:0070069)
0.1	0.8	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	0.4	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	1.3	GO:0042629	mast cell granule(GO:0042629)
0.1	0.1	GO:0097225	sperm midpiece(GO:0097225)
0.1	2.8	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	1.9	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.1	0.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.5	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.5	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	0.7	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1	0.7	GO:0043194	axon initial segment(GO:0043194)
0.1	0.3	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.9	GO:0036038	MKS complex(GO:0036038)
0.1	0.2	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.1	0.4	GO:0097427	microtubule bundle(GO:0097427)
0.1	0.4	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	0.2	GO:0008091	spectrin(GO:0008091)
0.1	0.9	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.4	GO:1904115	axon cytoplasm(GO:1904115)
0.1	0.2	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1	0.2	GO:0070195	growth hormone receptor complex(GO:0070195)
0.1	0.5	GO:0032039	integrator complex(GO:0032039)
0.1	0.2	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.1	1.3	GO:0034706	sodium channel complex(GO:0034706)
0.1	4.1	GO:0070469	respiratory chain(GO:0070469)
0.1	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.1	1.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	0.7	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.3	GO:1990391	DNA repair complex(GO:1990391)
0.1	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	1.2	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	0.4	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	1.3	GO:0032420	stereocilium(GO:0032420)
0.1	2.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	2.4	GO:0005819	spindle(GO:0005819)
0.1	0.2	GO:0032585	multivesicular body membrane(GO:0032585)
0.1	0.2	GO:0030891	VCB complex(GO:0030891)
0.1	3.3	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	3.8	GO:0035580	specific granule lumen(GO:0035580)
0.1	0.6	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	0.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.0	0.1	GO:0034455	t-UTP complex(GO:0034455)
0.0	4.6	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.2	GO:0032009	early phagosome(GO:0032009)
0.0	0.4	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	2.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	6.7	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	1.7	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:1990298	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.5	GO:0043596	nuclear replication fork(GO:0043596)
0.0	2.8	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0018444	translation release factor complex(GO:0018444)
0.0	7.4	GO:0030016	myofibril(GO:0030016)
0.0	4.3	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	4.8	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0016234	inclusion body(GO:0016234)
0.0	0.0	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	1.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.2	GO:0071817	MMXD complex(GO:0071817)
0.0	0.6	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.7	GO:0031082	BLOC complex(GO:0031082)
0.0	0.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	0.3	GO:0032797	SMN complex(GO:0032797)
0.0	0.4	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	1.2	GO:0045178	basal part of cell(GO:0045178)
0.0	1.0	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	0.4	GO:0000346	transcription export complex(GO:0000346)
0.0	0.3	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	4.0	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.0	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	0.4	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.6	GO:0034709	methylosome(GO:0034709)
0.0	1.8	GO:0043204	perikaryon(GO:0043204)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	0.2	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.5	GO:0071565	nBAF complex(GO:0071565)
0.0	3.5	GO:0043209	myelin sheath(GO:0043209)
0.0	0.3	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.2	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	1.3	GO:0015030	Cajal body(GO:0015030)
0.0	0.0	GO:1902710	GABA receptor complex(GO:1902710)
0.0	0.2	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.1	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.1	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.0	1.0	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	3.6	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.3	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	1.0	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	7.8	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.0	GO:0032982	myosin filament(GO:0032982)
0.0	0.0	GO:1990462	omegasome(GO:1990462)
0.0	0.1	GO:0005602	complement component C1 complex(GO:0005602)
0.0	0.0	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.2	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	3.8	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.3	GO:0019867	outer membrane(GO:0019867)
0.0	0.1	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.0	0.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.6	GO:0016235	aggresome(GO:0016235)
0.0	0.3	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	1.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	0.1	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0	0.4	GO:0031594	neuromuscular junction(GO:0031594)
0.0	4.0	GO:0005874	microtubule(GO:0005874)
0.0	0.0	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.4	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0033011	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	0.9	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.1	GO:0034703	cation channel complex(GO:0034703)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	1.3	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.0	GO:0097447	dendritic tree(GO:0097447)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.3	GO:0043679	axon terminus(GO:0043679)
0.0	0.1	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.1	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.7	GO:0005643	nuclear pore(GO:0005643)
0.0	0.0	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.6	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.1	GO:0042613	MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:0047023	androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.2	0.6	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
0.1	0.7	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.8	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.5	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.1	0.7	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.7	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	2.0	GO:0031489	myosin V binding(GO:0031489)
0.1	0.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.3	GO:0070026	nitric oxide binding(GO:0070026)
0.1	0.9	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.3	GO:0070905	serine binding(GO:0070905)
0.1	0.3	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.4	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0	0.2	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.0	0.3	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.9	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.5	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.4	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.3	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.1	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.3	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.1	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.0	0.0	GO:0030375	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	1.0	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.4	GO:0001671	ATPase activator activity(GO:0001671)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.0	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	1.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.3	1.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.3	1.3	GO:0070404	NADH binding(GO:0070404)
0.2	0.7	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2	1.0	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2	1.4	GO:0042610	CD8 receptor binding(GO:0042610)
0.2	1.3	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2	2.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	2.8	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2	0.5	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.2	1.0	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.4	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	1.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.7	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	2.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	1.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	0.8	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	0.3	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1	3.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	2.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.5	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	1.5	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	1.3	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.2	GO:0031859	platelet activating factor receptor binding(GO:0031859)
0.1	0.9	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.9	GO:0008199	ferric iron binding(GO:0008199)
0.1	1.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.8	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1	0.2	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	0.3	GO:0036033	mediator complex binding(GO:0036033)
0.1	0.3	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	0.6	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	1.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.2	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.0	0.8	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.7	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699) ethanol binding(GO:0035276)
0.0	0.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	1.4	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	1.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.3	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.9	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.7	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.2	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0031877	somatostatin receptor binding(GO:0031877)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.4	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	2.3	GO:0097110	scaffold protein binding(GO:0097110)
0.0	1.8	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.7	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	2.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.2	GO:0022840	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0	0.2	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0	0.2	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.4	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.3	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.3	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	0.2	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.6	GO:0050699	WW domain binding(GO:0050699)
0.0	1.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.0	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.1	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.0	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.8	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.6	1.8	GO:0036024	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.5	2.7	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.5	2.0	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.5	3.8	GO:0016012	sarcoglycan complex(GO:0016012)
0.4	4.8	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.4	1.6	GO:0045179	apical cortex(GO:0045179)
0.4	1.6	GO:0097454	Schwann cell microvillus(GO:0097454)
0.4	4.8	GO:0043203	axon hillock(GO:0043203)
0.4	1.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.3	1.4	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.3	2.0	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.3	1.3	GO:0043260	laminin-11 complex(GO:0043260)
0.3	3.8	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3	5.0	GO:0031089	platelet dense granule lumen(GO:0031089)
0.3	1.2	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.3	3.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.3	1.0	GO:0070695	FHF complex(GO:0070695)
0.2	2.5	GO:0097413	Lewy body(GO:0097413)
0.2	1.5	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.2	3.5	GO:0030478	actin cap(GO:0030478)
0.2	4.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2	0.8	GO:0032044	DSIF complex(GO:0032044)
0.2	9.9	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	0.9	GO:1990393	3M complex(GO:1990393)
0.2	0.7	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.2	0.9	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.2	1.7	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2	0.2	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.2	17.7	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.2	3.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	0.9	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.1	3.5	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.4	GO:0005960	glycine cleavage complex(GO:0005960)
0.1	3.0	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.7	GO:0042643	actomyosin, actin portion(GO:0042643)
0.1	1.4	GO:0042612	MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.1	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.1	1.0	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	1.3	GO:0071953	elastic fiber(GO:0071953)
0.1	0.8	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.4	GO:0070557	PCNA-p21 complex(GO:0070557)
0.1	0.4	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	1.7	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	1.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.6	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	0.8	GO:0032584	growth cone membrane(GO:0032584)
0.1	35.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	0.2	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	0.4	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.1	0.3	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	1.0	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.5	GO:0031045	dense core granule(GO:0031045)
0.1	1.0	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	1.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1	0.7	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.3	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.1	0.3	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.1	0.7	GO:0019814	immunoglobulin complex(GO:0019814)
0.1	0.1	GO:0016460	myosin II complex(GO:0016460)
0.1	0.4	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	0.6	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.1	0.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	1.5	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1	0.3	GO:0060187	cell pole(GO:0060187)
0.1	1.4	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.2	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
0.1	1.0	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.3	GO:0045160	myosin I complex(GO:0045160)
0.1	0.8	GO:0033010	paranodal junction(GO:0033010)
0.1	0.8	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	0.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.1	0.2	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.1	1.3	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.5	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	1.4	GO:0009986	cell surface(GO:0009986)
0.1	1.7	GO:0031105	septin complex(GO:0031105)
0.1	0.5	GO:0035976	AP1 complex(GO:0035976)
0.1	0.5	GO:0071203	WASH complex(GO:0071203)
0.1	1.2	GO:0005687	U4 snRNP(GO:0005687)
0.1	0.8	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1	0.4	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	3.5	GO:0005902	microvillus(GO:0005902)
0.1	0.5	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0005873	plus-end kinesin complex(GO:0005873)
0.1	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.1	1.7	GO:0032982	myosin filament(GO:0032982)
0.1	0.3	GO:0031673	H zone(GO:0031673)
0.1	0.2	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
0.1	0.2	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1	0.7	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	0.6	GO:0044327	dendritic spine head(GO:0044327)
0.1	1.5	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.8	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.8	GO:0031209	SCAR complex(GO:0031209)
0.1	0.4	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.1	0.5	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	0.6	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.1	1.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.4	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	2.1	GO:0000421	autophagosome membrane(GO:0000421)
0.1	1.5	GO:0036379	myofilament(GO:0036379)
0.1	3.8	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	0.4	GO:0032010	phagolysosome(GO:0032010)
0.1	0.2	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1	1.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	2.9	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.3	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.7	GO:0043679	axon terminus(GO:0043679)
0.0	5.0	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0071159	NF-kappaB complex(GO:0071159)
0.0	0.3	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.3	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.7	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.5	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.0	0.1	GO:0033565	ESCRT-0 complex(GO:0033565)
0.0	1.0	GO:0016020	membrane(GO:0016020)
0.0	0.2	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	0.3	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:1990075	periciliary membrane compartment(GO:1990075)
0.0	0.5	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.7	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0002177	manchette(GO:0002177)
0.0	2.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0045298	tubulin complex(GO:0045298)
0.0	0.3	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.5	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.5	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.3	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0	0.8	GO:0031527	filopodium membrane(GO:0031527)
0.0	7.7	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.2	GO:1990812	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0	0.2	GO:0061617	MICOS complex(GO:0061617)
0.0	1.8	GO:0043195	terminal bouton(GO:0043195)
0.0	0.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	2.1	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.2	GO:0036021	endolysosome lumen(GO:0036021)
0.0	0.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.3	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.7	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.4	GO:0032994	protein-lipid complex(GO:0032994)
0.0	2.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	2.0	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	1.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.7	GO:0071564	npBAF complex(GO:0071564)
0.0	1.1	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.4	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.8	GO:0099738	cell cortex region(GO:0099738)
0.0	0.7	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.4	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	1.4	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	0.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.3	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	1.3	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.0	0.1	GO:0035370	UBC13-UEV1A complex(GO:0035370)
0.0	0.0	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.3	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.2	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.1	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.5	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.7	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.3	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.2	GO:0097486	late endosome lumen(GO:0031906) multivesicular body lumen(GO:0097486)
0.0	0.3	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0034709	methylosome(GO:0034709)
0.0	0.3	GO:0043204	perikaryon(GO:0043204)
0.0	0.3	GO:0043218	compact myelin(GO:0043218)
0.0	0.6	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.0	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.1	GO:0005921	gap junction(GO:0005921)
0.0	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.8	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0055037	recycling endosome(GO:0055037)
0.0	0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.0	0.1	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.0	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.1	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	1.0	GO:0072562	blood microparticle(GO:0072562)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.4	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	PID ALK2 PATHWAY	ALK2 signaling events
0.1	3.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.8	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	2.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	3.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	2.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.6	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	2.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	3.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	7.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.8	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.7	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	PID PTP1B PATHWAY	Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	1.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	2.8	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	1.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	3.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	4.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.5	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	10.7	GO:0097325	melanocyte proliferation(GO:0097325)
2.5	9.8	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
1.9	23.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.6	4.9	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
1.6	6.3	GO:0046086	adenosine biosynthetic process(GO:0046086)
1.5	11.9	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
1.3	3.9	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.3	5.1	GO:0021564	vagus nerve development(GO:0021564)
1.1	6.7	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
1.0	9.1	GO:0060591	chondroblast differentiation(GO:0060591)
1.0	11.7	GO:0048251	elastic fiber assembly(GO:0048251)
0.8	2.5	GO:0060592	mammary gland formation(GO:0060592)
0.8	2.4	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.7	3.4	GO:0044855	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.7	2.6	GO:0009956	radial pattern formation(GO:0009956)
0.6	5.2	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.6	1.3	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.6	1.9	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.6	1.9	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.6	3.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.6	4.3	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.5	1.6	GO:0045210	FasL biosynthetic process(GO:0045210)
0.5	2.5	GO:0048539	bone marrow development(GO:0048539)
0.5	1.5	GO:0007412	axon target recognition(GO:0007412)
0.5	0.5	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.5	1.4	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.4	1.3	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4	5.7	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.4	2.3	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.4	5.0	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.4	1.5	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.4	2.9	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3	0.7	GO:0035989	tendon development(GO:0035989)
0.3	1.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.3	1.7	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.3	1.3	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.3	2.6	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3	0.6	GO:0030262	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.3	1.1	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.3	0.3	GO:0060437	lung growth(GO:0060437)
0.3	0.8	GO:0061317	arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3	3.2	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.3	1.8	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.2	2.5	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	3.4	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2	1.7	GO:0070294	renal sodium ion absorption(GO:0070294)
0.2	1.2	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2	1.8	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.2	0.9	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.2	1.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	15.9	GO:0030574	collagen catabolic process(GO:0030574)
0.2	2.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2	1.6	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2	3.3	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2	2.5	GO:0035372	protein localization to microtubule(GO:0035372)
0.2	0.6	GO:0002384	hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.2	1.0	GO:0097338	response to clozapine(GO:0097338)
0.2	2.8	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.2	0.9	GO:0007619	courtship behavior(GO:0007619)
0.2	1.8	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2	0.5	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.2	1.0	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.2	0.5	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.2	3.3	GO:0001765	membrane raft assembly(GO:0001765)
0.2	1.2	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2	0.6	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.2	1.0	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2	1.9	GO:0021814	cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.2	0.6	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.2	3.6	GO:0003334	keratinocyte development(GO:0003334)
0.2	3.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	2.0	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.6	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.7	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	0.3	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.1	0.5	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1	1.1	GO:1900625	monocyte aggregation(GO:0070487) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	3.4	GO:0071711	basement membrane organization(GO:0071711)
0.1	0.4	GO:0035993	subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1	0.4	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1	0.8	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.5	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1	1.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.6	GO:1990504	dense core granule exocytosis(GO:1990504)
0.1	1.9	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	1.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.5	GO:0019087	transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.1	1.4	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	6.1	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.1	0.7	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1	0.4	GO:0071306	cellular response to vitamin E(GO:0071306) response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1	0.4	GO:0061373	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1	0.6	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	1.9	GO:0060004	reflex(GO:0060004)
0.1	0.3	GO:0001172	transcription, RNA-templated(GO:0001172)
0.1	1.1	GO:0030834	regulation of actin filament depolymerization(GO:0030834)
0.1	0.3	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	7.4	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	0.4	GO:1904753	negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.1	0.4	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.1	1.0	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.9	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	0.3	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	1.5	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.2	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.1	0.5	GO:0003344	pericardium morphogenesis(GO:0003344)
0.1	0.5	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	0.6	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	0.9	GO:0055001	muscle cell development(GO:0055001)
0.1	1.0	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.2	GO:1903028	positive regulation of opsonization(GO:1903028)
0.1	0.7	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1	0.5	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.7	GO:0042373	vitamin K metabolic process(GO:0042373)
0.1	1.6	GO:1900120	regulation of receptor binding(GO:1900120)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	0.4	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.3	GO:0006041	glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.1	1.2	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.1	0.2	GO:0060796	regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1	0.5	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	1.5	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.2	GO:0050917	sensory perception of umami taste(GO:0050917)
0.1	1.6	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.1	0.5	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.1	0.8	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	0.2	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1	0.8	GO:0050821	protein stabilization(GO:0050821)
0.1	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	1.3	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.2	GO:0070778	L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0	0.5	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.8	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.2	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.0	0.1	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0	0.6	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.9	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.3	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.3	GO:0052565	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0	0.2	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.7	GO:0006828	manganese ion transport(GO:0006828)
0.0	1.5	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.1	GO:0032808	lacrimal gland development(GO:0032808)
0.0	5.3	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.0	0.3	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0002879	positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0	0.1	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.4	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0	1.5	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	1.4	GO:0016486	peptide hormone processing(GO:0016486)
0.0	1.0	GO:0008038	neuron recognition(GO:0008038)
0.0	1.0	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0	0.7	GO:0010669	epithelial structure maintenance(GO:0010669)
0.0	0.3	GO:0061042	vascular wound healing(GO:0061042)
0.0	1.6	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	1.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	0.5	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.3	GO:0044546	NLRP3 inflammasome complex assembly(GO:0044546)
0.0	0.4	GO:0045116	protein neddylation(GO:0045116)
0.0	2.6	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	1.7	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.1	GO:0035606	induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0	0.7	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	1.0	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.1	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.0	0.4	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0009386	translational attenuation(GO:0009386)
0.0	1.2	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.5	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.2	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.2	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0070305	response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0	0.0	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0	0.6	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.0	0.3	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.4	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.4	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	1.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	1.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.1	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.0	0.1	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	1.2	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.4	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.2	GO:1904896	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0	0.4	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.2	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0060157	urinary bladder development(GO:0060157)
0.0	1.3	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.0	0.2	GO:0060850	regulation of transcription involved in cell fate commitment(GO:0060850)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0003409	optic cup structural organization(GO:0003409)
0.0	0.7	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.3	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.6	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.4	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0	1.4	GO:0043542	endothelial cell migration(GO:0043542)
0.0	0.3	GO:0060393	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) pathway-restricted SMAD protein phosphorylation(GO:0060389) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.3	GO:0046326	positive regulation of glucose import(GO:0046326)
0.0	0.1	GO:0032411	positive regulation of transporter activity(GO:0032411)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.6	4.8	GO:0034455	t-UTP complex(GO:0034455)
1.4	8.5	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
1.4	5.6	GO:0044611	nuclear pore inner ring(GO:0044611)
1.3	2.5	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
1.1	4.6	GO:0000799	nuclear condensin complex(GO:0000799)
1.1	13.4	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.1	5.5	GO:0000408	EKC/KEOPS complex(GO:0000408)
1.1	4.4	GO:0071001	U4/U6 snRNP(GO:0071001)
1.1	3.3	GO:0031417	NatC complex(GO:0031417)
1.1	7.5	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
1.0	4.0	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.9	2.7	GO:0030689	Noc complex(GO:0030689)
0.9	2.7	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.9	6.1	GO:0016272	prefoldin complex(GO:0016272)
0.8	2.5	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
0.8	9.2	GO:0005688	U6 snRNP(GO:0005688)
0.8	3.3	GO:0001940	male pronucleus(GO:0001940)
0.8	1.6	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.8	3.2	GO:0005846	nuclear cap binding complex(GO:0005846)
0.8	3.9	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.8	14.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.8	4.6	GO:0000796	condensin complex(GO:0000796)
0.7	5.1	GO:0031298	replication fork protection complex(GO:0031298)
0.7	2.1	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.7	4.9	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.7	6.9	GO:0000439	core TFIIH complex(GO:0000439)
0.7	2.0	GO:0019034	viral replication complex(GO:0019034)
0.7	8.8	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.7	2.7	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.7	4.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.7	6.6	GO:0097255	R2TP complex(GO:0097255)
0.6	1.9	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.6	10.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.6	9.0	GO:0005662	DNA replication factor A complex(GO:0005662)
0.6	3.8	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.6	6.3	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.6	1.8	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.6	6.7	GO:0042555	MCM complex(GO:0042555)
0.6	3.0	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.6	16.0	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.6	2.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.6	2.3	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.6	5.1	GO:0005638	lamin filament(GO:0005638)
0.6	6.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.6	5.0	GO:0032039	integrator complex(GO:0032039)
0.6	1.7	GO:0031262	Ndc80 complex(GO:0031262)
0.5	4.9	GO:0070652	HAUS complex(GO:0070652)
0.5	2.7	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.5	2.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.5	2.6	GO:0071817	MMXD complex(GO:0071817)
0.5	1.5	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.5	4.6	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.5	1.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.5	0.5	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.5	8.8	GO:0034709	methylosome(GO:0034709)
0.5	3.9	GO:0032133	chromosome passenger complex(GO:0032133)
0.5	25.6	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5	13.0	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.5	0.5	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.5	2.8	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.5	2.3	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.5	2.3	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.5	1.4	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.5	4.6	GO:0000243	commitment complex(GO:0000243)
0.5	1.8	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5	0.9	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.5	1.8	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.4	1.8	GO:0043293	apoptosome(GO:0043293)
0.4	2.6	GO:0061689	tricellular tight junction(GO:0061689)
0.4	5.3	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.4	3.1	GO:0019815	B cell receptor complex(GO:0019815)
0.4	4.3	GO:0000800	lateral element(GO:0000800)
0.4	8.6	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.4	9.0	GO:0032040	small-subunit processome(GO:0032040)
0.4	4.7	GO:0005686	U2 snRNP(GO:0005686)
0.4	1.3	GO:0070939	Dsl1p complex(GO:0070939)
0.4	1.3	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.4	5.0	GO:0030008	TRAPP complex(GO:0030008)
0.4	2.9	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4	2.5	GO:0005927	muscle tendon junction(GO:0005927)
0.4	2.0	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.4	2.8	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4	1.2	GO:0032302	MutSbeta complex(GO:0032302)
0.4	2.3	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.4	14.4	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4	3.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.4	1.1	GO:0018444	translation release factor complex(GO:0018444)
0.4	8.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3	2.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.3	2.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.3	6.2	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.3	1.0	GO:0098536	deuterosome(GO:0098536)
0.3	5.6	GO:0045277	respiratory chain complex IV(GO:0045277)
0.3	0.3	GO:0031201	SNARE complex(GO:0031201)
0.3	3.6	GO:0031595	nuclear proteasome complex(GO:0031595)
0.3	3.9	GO:0000812	Swr1 complex(GO:0000812)
0.3	3.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3	0.3	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.3	1.0	GO:1990423	RZZ complex(GO:1990423)
0.3	0.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.3	2.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.3	2.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3	1.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.3	0.6	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.3	0.6	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.3	0.3	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3	0.9	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.3	2.7	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.3	2.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.3	3.8	GO:0001673	male germ cell nucleus(GO:0001673)
0.3	1.5	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3	2.6	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.3	2.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.3	1.4	GO:0097149	centralspindlin complex(GO:0097149)
0.3	3.4	GO:0035861	site of double-strand break(GO:0035861)
0.3	6.6	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.3	1.1	GO:0070985	TFIIK complex(GO:0070985)
0.3	1.9	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.3	0.8	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.3	2.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.3	2.0	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.2	0.7	GO:0005873	plus-end kinesin complex(GO:0005873)
0.2	1.7	GO:0030061	mitochondrial crista(GO:0030061)
0.2	4.7	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2	1.2	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.2	2.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.2	17.9	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.2	1.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	2.3	GO:0000788	nuclear nucleosome(GO:0000788)
0.2	0.7	GO:0070876	SOSS complex(GO:0070876)
0.2	4.8	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	1.1	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.2	0.4	GO:0030893	meiotic cohesin complex(GO:0030893)
0.2	0.7	GO:0070847	core mediator complex(GO:0070847)
0.2	0.2	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2	1.9	GO:0043203	axon hillock(GO:0043203)
0.2	10.4	GO:0015030	Cajal body(GO:0015030)
0.2	0.8	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.2	13.8	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2	0.2	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.2	0.4	GO:0035253	ciliary rootlet(GO:0035253)
0.2	0.6	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.2	2.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	1.0	GO:0032021	NELF complex(GO:0032021)
0.2	0.8	GO:0070552	BRISC complex(GO:0070552)
0.2	1.2	GO:0030686	90S preribosome(GO:0030686)
0.2	3.3	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2	2.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.2	7.1	GO:0090544	BAF-type complex(GO:0090544)
0.2	0.4	GO:0043034	costamere(GO:0043034)
0.2	1.4	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414) NatA complex(GO:0031415)
0.2	0.6	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.2	2.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.2	1.8	GO:0005684	U2-type spliceosomal complex(GO:0005684)
0.2	0.8	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2	1.8	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.2	15.9	GO:0000793	condensed chromosome(GO:0000793)
0.2	2.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	3.6	GO:0000242	pericentriolar material(GO:0000242)
0.2	1.5	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2	1.0	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2	1.3	GO:0097427	microtubule bundle(GO:0097427)
0.2	2.2	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.2	0.9	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.2	0.7	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.2	0.9	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.2	1.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2	1.7	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	1.5	GO:0072546	ER membrane protein complex(GO:0072546)
0.2	1.0	GO:0001520	outer dense fiber(GO:0001520)
0.2	0.7	GO:0031085	BLOC-3 complex(GO:0031085)
0.2	0.3	GO:0032301	MutSalpha complex(GO:0032301)
0.2	0.5	GO:0030125	clathrin vesicle coat(GO:0030125)
0.2	1.8	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2	0.5	GO:0043159	acrosomal matrix(GO:0043159)
0.2	0.2	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.2	1.2	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.2	2.6	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2	0.8	GO:0032584	growth cone membrane(GO:0032584)
0.2	0.8	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.2	3.4	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.2	23.1	GO:0005681	spliceosomal complex(GO:0005681)
0.2	1.8	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.2	4.8	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2	0.9	GO:0031616	spindle pole centrosome(GO:0031616)
0.2	1.7	GO:0044666	MLL3/4 complex(GO:0044666)
0.2	0.6	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2	0.6	GO:0032044	DSIF complex(GO:0032044)
0.2	1.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.2	0.9	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.2	0.5	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1	2.7	GO:0097342	ripoptosome(GO:0097342)
0.1	0.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	0.6	GO:0033186	CAF-1 complex(GO:0033186)
0.1	6.0	GO:0005871	kinesin complex(GO:0005871)
0.1	1.2	GO:0031931	TORC1 complex(GO:0031931)
0.1	2.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.6	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	2.0	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	0.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	4.0	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	0.3	GO:0005883	neurofilament(GO:0005883)
0.1	0.4	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	7.7	GO:0005643	nuclear pore(GO:0005643)
0.1	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.1	0.7	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.4	GO:0043601	nuclear replisome(GO:0043601)
0.1	2.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.5	GO:0000322	storage vacuole(GO:0000322)
0.1	0.5	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.4	GO:0001740	Barr body(GO:0001740)
0.1	0.1	GO:0032009	early phagosome(GO:0032009)
0.1	0.4	GO:0043291	RAVE complex(GO:0043291)
0.1	0.3	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	3.2	GO:0031143	pseudopodium(GO:0031143)
0.1	0.1	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	2.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	0.4	GO:0042382	paraspeckles(GO:0042382)
0.1	0.5	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	7.1	GO:0000775	chromosome, centromeric region(GO:0000775)
0.1	0.4	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
0.1	0.4	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.5	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	0.7	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.9	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	1.1	GO:0097386	glial cell projection(GO:0097386)
0.1	0.7	GO:0045120	pronucleus(GO:0045120)
0.1	0.5	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.2	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	1.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	33.4	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.1	1.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	1.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	0.6	GO:0070187	telosome(GO:0070187)
0.1	0.1	GO:0060091	kinocilium(GO:0060091) kinociliary basal body(GO:1902636)
0.1	1.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	1.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	0.3	GO:0034657	GID complex(GO:0034657)
0.1	1.6	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.1	0.8	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.2	GO:0071159	NF-kappaB complex(GO:0071159)
0.1	0.6	GO:1990357	terminal web(GO:1990357)
0.1	1.3	GO:0017119	Golgi transport complex(GO:0017119)
0.1	0.7	GO:0070938	contractile ring(GO:0070938)
0.1	0.3	GO:0001652	granular component(GO:0001652)
0.1	0.3	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1	1.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.6	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	0.6	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	0.1	GO:0044393	microspike(GO:0044393)
0.1	0.5	GO:0031905	early endosome lumen(GO:0031905)
0.1	0.4	GO:0030891	VCB complex(GO:0030891)
0.1	0.4	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.1	0.1	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.1	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.1	72.6	GO:0005730	nucleolus(GO:0005730)
0.1	1.1	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	1.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	0.3	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.1	0.3	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	0.6	GO:0036157	outer dynein arm(GO:0036157)
0.1	0.8	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.3	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	0.2	GO:0005960	glycine cleavage complex(GO:0005960)
0.1	0.2	GO:0090543	Flemming body(GO:0090543)
0.1	1.3	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.1	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	1.0	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.1	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
0.1	1.4	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	1.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	1.6	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.4	GO:0000781	chromosome, telomeric region(GO:0000781)
0.1	0.7	GO:0097440	apical dendrite(GO:0097440)
0.1	0.4	GO:0071437	invadopodium(GO:0071437)
0.1	0.4	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	1.4	GO:0016592	mediator complex(GO:0016592)
0.1	0.8	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.3	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.1	0.1	GO:0030894	replisome(GO:0030894)
0.1	1.9	GO:0042629	mast cell granule(GO:0042629)
0.1	0.3	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.3	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.1	2.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.1	0.5	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.1	0.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.3	GO:0033503	HULC complex(GO:0033503)
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.2	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	3.1	GO:0042571	immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.1	0.2	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.1	0.5	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	0.6	GO:0000502	proteasome complex(GO:0000502)
0.1	2.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	2.1	GO:0000786	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.1	0.9	GO:0000145	exocyst(GO:0000145)
0.1	0.9	GO:0005839	proteasome core complex(GO:0005839)
0.1	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	0.7	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	4.3	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	1.8	GO:0031970	organelle envelope lumen(GO:0031970)
0.1	10.8	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.1	3.2	GO:0044450	microtubule organizing center part(GO:0044450)
0.1	0.3	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	2.8	GO:0016363	nuclear matrix(GO:0016363)
0.1	0.5	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	0.2	GO:0036020	endolysosome membrane(GO:0036020)
0.1	1.0	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	1.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.7	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	1.2	GO:0070461	SAGA-type complex(GO:0070461)
0.1	0.3	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	0.7	GO:0016234	inclusion body(GO:0016234)
0.0	10.6	GO:0016607	nuclear speck(GO:0016607)
0.0	12.2	GO:0031965	nuclear membrane(GO:0031965)
0.0	3.8	GO:0008021	synaptic vesicle(GO:0008021)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.4	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	1.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.3	GO:0030904	retromer complex(GO:0030904)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	4.4	GO:0005840	ribosome(GO:0005840)
0.0	1.5	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0048475	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0	0.3	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.6	GO:0031209	SCAR complex(GO:0031209)
0.0	0.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	0.5	GO:0070382	exocytic vesicle(GO:0070382)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	2.7	GO:0000922	spindle pole(GO:0000922)
0.0	6.4	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.3	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:1990031	pinceau fiber(GO:1990031)
0.0	3.8	GO:0031968	organelle outer membrane(GO:0031968)
0.0	2.3	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0032010	phagolysosome(GO:0032010)
0.0	0.1	GO:0036026	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	1.0	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.4	GO:0061702	inflammasome complex(GO:0061702)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.3	GO:0044439	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.6	GO:0032982	myosin filament(GO:0032982)
0.0	0.2	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	39.4	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0	0.5	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	1.1	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.0	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.4	GO:0030133	transport vesicle(GO:0030133)
0.0	0.3	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.7	GO:0070821	tertiary granule membrane(GO:0070821)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.9	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	3.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	1.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	1.4	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	2.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	2.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	2.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	3.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	1.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	8.6	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
1.7	5.0	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
1.6	4.7	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
1.3	4.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
1.2	3.7	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
1.1	7.6	GO:0048408	epidermal growth factor binding(GO:0048408)
0.8	9.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.8	3.2	GO:0032217	riboflavin transporter activity(GO:0032217)
0.8	3.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.7	2.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.7	2.8	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.7	2.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.6	2.5	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6	2.9	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.5	3.6	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.5	4.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.5	2.5	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.5	1.5	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.5	1.4	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.4	1.8	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.4	1.3	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.4	0.4	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.4	2.2	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.4	4.7	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.4	8.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.4	3.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4	1.6	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.4	2.8	GO:0061133	endopeptidase activator activity(GO:0061133)
0.4	2.8	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.4	1.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.4	8.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.4	2.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.4	1.5	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4	6.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.4	3.7	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4	1.5	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
0.4	1.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.4	1.8	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.3	1.4	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.3	0.3	GO:0001132	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.3	2.0	GO:0035500	MH2 domain binding(GO:0035500)
0.3	1.7	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3	1.3	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3	1.9	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3	3.8	GO:0034452	dynactin binding(GO:0034452)
0.3	1.6	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3	1.9	GO:0098821	BMP receptor activity(GO:0098821)
0.3	1.9	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.3	0.9	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3	5.8	GO:0051787	misfolded protein binding(GO:0051787)
0.3	5.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.3	0.6	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3	0.9	GO:0019961	interferon binding(GO:0019961)
0.3	8.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.3	2.3	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.3	6.7	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3	1.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.3	1.4	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.3	0.8	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.3	1.8	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3	2.8	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.3	1.0	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.2	1.7	GO:0050815	phosphoserine binding(GO:0050815)
0.2	3.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.2	5.1	GO:0000339	RNA cap binding(GO:0000339)
0.2	1.2	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.2	0.9	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.2	1.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.2	1.3	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.2	0.9	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2	3.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.2	2.4	GO:0015266	protein channel activity(GO:0015266)
0.2	0.7	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2	0.6	GO:0034511	U3 snoRNA binding(GO:0034511)
0.2	0.6	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2	3.0	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.2	0.4	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.2	2.7	GO:0003993	acid phosphatase activity(GO:0003993)
0.2	1.2	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.2	1.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2	0.8	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	0.6	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2	1.8	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	4.0	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2	1.6	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	2.4	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.2	0.2	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.2	0.6	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2	6.0	GO:0001671	ATPase activator activity(GO:0001671)
0.2	1.4	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	19.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	3.0	GO:0070513	death domain binding(GO:0070513)
0.2	0.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	1.3	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.2	0.6	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.2	0.7	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.2	6.5	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.2	9.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.2	2.1	GO:0031386	protein tag(GO:0031386)
0.2	2.6	GO:0050699	WW domain binding(GO:0050699)
0.2	1.4	GO:0004064	arylesterase activity(GO:0004064)
0.2	0.8	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.2	1.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.2	1.3	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2	0.9	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2	5.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.2	2.0	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.4	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	7.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.4	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1	1.4	GO:0008097	5S rRNA binding(GO:0008097)
0.1	0.7	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	1.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	2.4	GO:0005522	profilin binding(GO:0005522)
0.1	0.7	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	0.4	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	5.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	3.7	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	1.9	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.4	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.4	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	0.8	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1	1.3	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	1.6	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.6	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.1	0.5	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	0.5	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	1.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	0.5	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	1.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.7	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	2.2	GO:0008170	N-methyltransferase activity(GO:0008170)
0.1	0.4	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.1	1.0	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	0.6	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	0.6	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1	0.5	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	2.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	1.9	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	1.1	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.5	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.5	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	0.3	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.1	2.4	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.1	8.9	GO:0019905	syntaxin binding(GO:0019905)
0.1	0.4	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	5.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	0.4	GO:0001055	RNA polymerase II activity(GO:0001055)
0.1	2.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.6	GO:1990446	U1 snRNP binding(GO:1990446)
0.1	1.8	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	0.3	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.1	0.3	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	1.9	GO:0016805	dipeptidase activity(GO:0016805)
0.1	3.3	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	0.3	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.1	1.4	GO:0045503	dynein light chain binding(GO:0045503)
0.1	1.0	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.1	1.7	GO:0016854	racemase and epimerase activity(GO:0016854)
0.1	0.5	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.7	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.4	GO:0050473	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1	0.4	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.5	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	1.6	GO:0043495	protein anchor(GO:0043495)
0.1	1.8	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.1	0.5	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.1	1.4	GO:0097602	cullin family protein binding(GO:0097602)
0.1	1.2	GO:0031014	troponin T binding(GO:0031014)
0.1	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.1	0.3	GO:0015232	heme transporter activity(GO:0015232)
0.1	3.9	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	3.3	GO:0003785	actin monomer binding(GO:0003785)
0.1	1.3	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	9.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.4	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.4	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.1	0.8	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.2	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.1	2.0	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1	1.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.3	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.2	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.2	GO:0030984	kininogen binding(GO:0030984)
0.1	0.2	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	1.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.1	0.5	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	3.4	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1	1.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.3	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.4	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.2	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1	2.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	3.4	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.1	5.3	GO:0019003	GDP binding(GO:0019003)
0.1	2.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	1.4	GO:0005537	mannose binding(GO:0005537)
0.1	4.2	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	1.5	GO:0030275	LRR domain binding(GO:0030275)
0.1	0.2	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	0.3	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.3	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	2.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.2	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.1	4.9	GO:0008135	translation factor activity, RNA binding(GO:0008135)
0.1	0.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	1.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.7	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	0.4	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.3	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.4	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	1.8	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	2.7	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	0.1	GO:0016426	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1	2.2	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	0.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.5	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.4	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.1	0.9	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	1.1	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	5.1	GO:0051082	unfolded protein binding(GO:0051082)
0.1	4.9	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.1	1.9	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	0.2	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.4	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.1	0.4	GO:1990459	transferrin receptor binding(GO:1990459)
0.1	0.5	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	7.2	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	0.4	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	0.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.7	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0033765	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.2	GO:0035877	death effector domain binding(GO:0035877)
0.0	1.3	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.9	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.0	GO:0070990	snRNP binding(GO:0070990)
0.0	1.2	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.5	GO:0000149	SNARE binding(GO:0000149)
0.0	0.3	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	1.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.2	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	0.7	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.9	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	1.0	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.4	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.4	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.6	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.4	GO:0016866	intramolecular transferase activity(GO:0016866)
0.0	0.1	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.0	0.1	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.0	0.5	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.6	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.4	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.9	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.0	0.6	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.4	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	6.8	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.2	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.6	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	3.8	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.7	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	1.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.3	GO:0032356	oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	7.3	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.1	GO:0004040	amidase activity(GO:0004040)
0.0	0.3	GO:0015103	inorganic anion transmembrane transporter activity(GO:0015103)
0.0	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.4	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.5	GO:0004559	alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.0	4.3	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0005046	KDEL sequence binding(GO:0005046)
0.0	0.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
0.0	0.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.8	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.2	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	0.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	8.0	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)
0.0	7.9	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.8	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0019107	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0	0.1	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0	0.6	GO:0015295	solute:proton symporter activity(GO:0015295)
0.0	0.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.6	GO:0071949	FAD binding(GO:0071949)
0.0	1.2	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.0	0.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.1	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.0	0.6	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.2	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.3	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	1.9	GO:0016247	channel regulator activity(GO:0016247)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	4.0	GO:0004857	enzyme inhibitor activity(GO:0004857)
0.0	0.2	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.5	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0	0.9	GO:0032947	protein complex scaffold(GO:0032947)
0.0	2.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)
0.0	0.5	GO:0005109	frizzled binding(GO:0005109)
0.0	14.8	GO:0003723	RNA binding(GO:0003723)
0.0	0.8	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	1.0	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.2	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.0	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	8.1	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:1990405	protein antigen binding(GO:1990405)
0.0	1.1	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.6	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	2.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	1.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.8	GO:0016853	isomerase activity(GO:0016853)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.3	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	3.8	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.9	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.7	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.8	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.9	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.7	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.3	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.5	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.7	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	10.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	4.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	1.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	2.5	PID AURORA A PATHWAY	Aurora A signaling
0.0	2.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	2.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.6	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	5.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.4	PID SHP2 PATHWAY	SHP2 signaling
0.0	1.2	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.8	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID ATM PATHWAY	ATM pathway
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.0	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.6	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.5	PID AURORA B PATHWAY	Aurora B signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0005607	laminin-2 complex(GO:0005607)
0.3	4.8	GO:0030478	actin cap(GO:0030478)
0.3	3.7	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	1.6	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.2	1.4	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.4	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	2.7	GO:0032433	filopodium tip(GO:0032433)
0.1	3.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.7	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	0.4	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	2.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.9	GO:0005610	laminin-5 complex(GO:0005610)
0.1	2.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	3.3	GO:0005605	basal lamina(GO:0005605)
0.1	0.3	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.1	0.2	GO:0031523	Myb complex(GO:0031523)
0.1	0.2	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.1	1.9	GO:0005685	U1 snRNP(GO:0005685)
0.1	4.1	GO:0005604	basement membrane(GO:0005604)
0.1	1.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.5	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.3	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.3	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.0	1.3	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0070187	telosome(GO:0070187)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.4	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	4.3	GO:0031901	early endosome membrane(GO:0031901)
0.0	16.1	GO:0005925	focal adhesion(GO:0005925)
0.0	2.0	GO:0005811	lipid particle(GO:0005811)
0.0	2.2	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.3	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.3	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.8	GO:0001533	cornified envelope(GO:0001533)
0.0	0.3	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.3	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	3.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.0	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0004998	transferrin receptor activity(GO:0004998)
0.4	1.6	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.3	0.9	GO:0002113	interleukin-33 binding(GO:0002113)
0.3	3.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.2	0.6	GO:0042015	interleukin-20 binding(GO:0042015)
0.2	1.0	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	2.4	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	1.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.9	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1	0.4	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	3.2	GO:0050699	WW domain binding(GO:0050699)
0.1	2.2	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.1	0.3	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.1	0.8	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	9.5	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	1.0	GO:0005537	mannose binding(GO:0005537)
0.0	1.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.3	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.2	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.3	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	1.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.7	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	1.1	GO:0019843	rRNA binding(GO:0019843)
0.0	0.7	GO:0005548	phospholipid transporter activity(GO:0005548)
0.0	1.2	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.2	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	2.7	GO:0051015	actin filament binding(GO:0051015)
0.0	0.3	GO:0004806	triglyceride lipase activity(GO:0004806)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.8	GO:0021564	vagus nerve development(GO:0021564)
0.7	2.7	GO:0046086	adenosine biosynthetic process(GO:0046086)
0.5	1.4	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4	1.4	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.3	1.0	GO:0072554	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.3	1.4	GO:0000103	sulfate assimilation(GO:0000103)
0.3	2.0	GO:0089700	protein kinase D signaling(GO:0089700)
0.3	0.8	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.3	1.1	GO:0036343	psychomotor behavior(GO:0036343)
0.2	2.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.2	1.0	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2	4.0	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	1.0	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.6	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	0.7	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1	2.2	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.7	GO:0051012	microtubule sliding(GO:0051012)
0.1	0.5	GO:1904579	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1	1.0	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	1.5	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.1	0.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	3.3	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.3	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	1.0	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.2	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1	1.2	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.6	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.7	GO:0032060	bleb assembly(GO:0032060)
0.0	2.0	GO:0008038	neuron recognition(GO:0008038)
0.0	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.2	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.4	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.2	GO:2000790	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.7	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.2	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.2	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	3.1	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.0	0.4	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.4	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.1	4.3	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.0	7.6	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.5	4.1	GO:1903278	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.4	1.5	GO:0032972	diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.3	0.8	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.3	0.8	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.3	1.3	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
0.2	2.9	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2	1.4	GO:0090131	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.2	0.8	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.2	0.7	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.2	1.6	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	0.9	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	1.5	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.4	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1	1.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	1.0	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1	0.7	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	1.4	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.6	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.3	GO:1990523	bone regeneration(GO:1990523)
0.1	0.5	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	1.6	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	1.8	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.1	0.3	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1	0.3	GO:0035026	leading edge cell differentiation(GO:0035026)
0.1	1.3	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.6	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	10.8	GO:0030449	regulation of complement activation(GO:0030449)
0.1	0.3	GO:0021815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1	0.4	GO:0030047	actin modification(GO:0030047)
0.1	0.5	GO:0015693	magnesium ion transport(GO:0015693)
0.1	1.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	0.2	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	0.5	GO:0030263	resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.0	1.4	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.4	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.6	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.3	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	1.0	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.9	GO:0051923	sulfation(GO:0051923)
0.0	1.4	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0	0.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.8	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.3	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	1.1	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	1.4	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.5	GO:0071711	basement membrane organization(GO:0071711)
0.0	0.1	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0	0.6	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.4	GO:0030728	ovulation(GO:0030728)
0.0	0.1	GO:0015793	glycerol transport(GO:0015793)
0.0	0.6	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.1	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0	0.2	GO:0010629	negative regulation of gene expression(GO:0010629)
0.0	0.3	GO:0006590	thyroid hormone generation(GO:0006590)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	4.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.9	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	3.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.9	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.0	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.4	2.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.4	2.4	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.3	1.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2	2.3	GO:0000439	core TFIIH complex(GO:0000439)
0.2	1.1	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2	0.6	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.2	0.8	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	0.7	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.8	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.5	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	0.6	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.5	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	1.0	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.9	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.3	GO:0005656	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1	0.6	GO:0090661	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1	0.8	GO:0042382	paraspeckles(GO:0042382)
0.1	0.4	GO:0070695	FHF complex(GO:0070695)
0.1	1.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	0.8	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	0.5	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.8	GO:0033391	chromatoid body(GO:0033391)
0.1	1.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	1.0	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	0.5	GO:0031415	NatA complex(GO:0031415)
0.1	0.3	GO:0035838	growing cell tip(GO:0035838)
0.1	0.4	GO:0030905	retromer, tubulation complex(GO:0030905)
0.1	1.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.4	GO:0001740	Barr body(GO:0001740)
0.1	0.2	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	1.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	0.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.4	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.2	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	1.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.2	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	1.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.3	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.2	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.5	GO:0097025	lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0005960	glycine cleavage complex(GO:0005960)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.4	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.7	GO:0031082	BLOC complex(GO:0031082)
0.0	0.4	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0	0.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.1	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0	0.9	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.9	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.5	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	1.4	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.6	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.6	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0097447	dendritic tree(GO:0097447)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0061700	GATOR2 complex(GO:0061700)
0.0	2.3	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	0.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.1	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.3	GO:0034709	methylosome(GO:0034709)
0.0	0.0	GO:0019034	viral replication complex(GO:0019034)
0.0	0.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:1990909	catenin complex(GO:0016342) Wnt signalosome(GO:1990909)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.6	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0034719	SMN-Sm protein complex(GO:0034719) Gemini of coiled bodies(GO:0097504)
0.0	0.9	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.8	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.0	GO:0031674	I band(GO:0031674)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.2	GO:0032445	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.3	1.0	GO:0072709	cellular response to sorbitol(GO:0072709)
0.2	0.5	GO:0032639	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1	0.9	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.7	GO:0010993	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
0.1	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.4	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	2.7	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	0.2	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1	0.4	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0030070	insulin processing(GO:0030070)
0.0	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0	0.3	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.3	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.2	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.2	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.2	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	1.9	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.2	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.3	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.0	0.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.0	0.1	GO:0007497	posterior midgut development(GO:0007497)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.0	0.5	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0043335	protein unfolding(GO:0043335)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.5	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	1.9	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.2	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.1	GO:0050915	sensory perception of sour taste(GO:0050915)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	2.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.6	6.7	GO:0043203	axon hillock(GO:0043203)
0.5	3.9	GO:0070552	BRISC complex(GO:0070552)
0.3	2.1	GO:0030061	mitochondrial crista(GO:0030061)
0.1	1.0	GO:0097452	GAIT complex(GO:0097452)
0.1	1.3	GO:0071953	elastic fiber(GO:0071953)
0.1	0.3	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.6	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.3	GO:0045180	basal cortex(GO:0045180)
0.0	1.8	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	7.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	1.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	1.6	GO:0000922	spindle pole(GO:0000922)
0.0	1.8	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	7.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	5.9	PID AURORA B PATHWAY	Aurora B signaling
0.1	0.9	PID FGF PATHWAY	FGF signaling pathway
0.1	0.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	2.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	3.0	PID ATR PATHWAY	ATR signaling pathway
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	1.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.9	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.4	PID ATM PATHWAY	ATM pathway
0.0	1.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	1.4	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.6	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	2.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.2	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.8	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.7	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.7	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	1.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.9	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.3	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.3	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.5	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	0.3	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	0.5	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	0.2	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:1990037	Lewy body core(GO:1990037)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.3	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.1	1.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	1.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	2.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	1.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.8	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.7	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	5.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	2.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	4.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	1.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.6	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	2.8	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	3.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	1.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.6	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.9	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	3.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	4.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	1.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	6.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	3.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	3.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	4.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	5.7	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	1.0	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	1.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.7	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	2.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	7.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	0.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	0.6	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	2.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	1.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	2.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	2.8	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	1.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	9.9	GO:0071438	invadopodium membrane(GO:0071438)
0.7	8.0	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6	1.9	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.6	7.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.3	5.5	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	7.1	GO:0043218	compact myelin(GO:0043218)
0.2	1.4	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.9	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1	11.3	GO:0005901	caveola(GO:0005901)
0.1	0.6	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	1.1	GO:0036020	endolysosome membrane(GO:0036020)
0.0	2.1	GO:0030286	dynein complex(GO:0030286)
0.0	0.6	GO:0044295	axonal growth cone(GO:0044295)
0.0	2.0	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	12.5	GO:0000790	nuclear chromatin(GO:0000790)
0.0	2.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	2.6	GO:0005882	intermediate filament(GO:0005882)
0.0	2.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	2.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	1.6	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	1.8	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	1.0	GO:0005581	collagen trimer(GO:0005581)
0.0	2.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	0.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	4.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.8	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	18.8	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.3	5.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	5.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	4.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	4.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	3.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	2.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	4.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	3.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	1.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	1.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	2.0	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	0.5	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.1	5.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	1.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	7.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	1.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	3.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	1.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	0.8	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.7	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	8.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.5	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	1.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	3.8	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	5.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	2.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	2.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	3.6	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	3.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	1.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.0	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4	1.2	GO:0019959	interleukin-8 binding(GO:0019959)
0.3	0.8	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2	3.1	GO:0016594	glycine binding(GO:0016594)
0.2	1.5	GO:0001515	opioid peptide activity(GO:0001515)
0.2	0.9	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2	2.4	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	0.4	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	2.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	3.9	GO:0042605	peptide antigen binding(GO:0042605)
0.1	2.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.4	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1	2.6	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	7.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.5	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	0.6	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	2.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	1.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.7	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.2	GO:0035276	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.1	0.6	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	1.8	GO:0001848	complement binding(GO:0001848)
0.0	4.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.5	GO:0016595	glutamate binding(GO:0016595)
0.0	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.0	0.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.5	GO:0070700	BMP receptor binding(GO:0070700)
0.0	1.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.8	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.5	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.5	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	2.6	GO:0051087	chaperone binding(GO:0051087)
0.0	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.5	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	1.1	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.8	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.8	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	1.2	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	2.9	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.6	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	1.0	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.0	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	1.7	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2	0.5	GO:0006566	threonine metabolic process(GO:0006566)
0.2	0.7	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.2	0.5	GO:0021569	rhombomere 3 development(GO:0021569)
0.2	0.8	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2	0.9	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
0.1	0.4	GO:0032289	central nervous system myelin formation(GO:0032289) detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1	0.7	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.1	0.3	GO:1904481	response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1	0.3	GO:0071030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1	0.3	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.7	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	0.9	GO:0015671	oxygen transport(GO:0015671)
0.1	0.3	GO:0070778	L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.1	0.4	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	0.3	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0	0.3	GO:1901029	adenine transport(GO:0015853) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.2	GO:0051621	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0	0.6	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.3	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.4	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.3	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0	0.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.4	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.3	GO:0015886	heme transport(GO:0015886)
0.0	1.5	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.2	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.4	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.5	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.2	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.2	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.1	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0	0.2	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.1	GO:1901098	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.0	0.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0002434	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) T cell extravasation(GO:0072683) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.6	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.5	GO:2000816	negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.4	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
1.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
1.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	3.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
1.8	40.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.3	27.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.9	23.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8	36.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.7	50.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.7	19.5	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.7	23.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.7	13.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.6	0.6	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.6	9.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.5	8.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.5	19.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.5	8.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.4	8.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	45.4	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.4	24.6	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.4	28.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.4	10.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.4	10.7	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.4	9.4	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.4	7.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.4	3.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.4	10.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.4	0.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	18.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	28.0	PID NOTCH PATHWAY	Notch signaling pathway
0.4	7.9	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.4	14.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.4	8.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.3	0.7	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.3	1.2	SIG CHEMOTAXIS	Genes related to chemotaxis
0.3	15.8	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.3	5.5	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.3	9.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.3	1.7	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3	10.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	3.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.3	3.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	14.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.2	5.7	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.2	5.9	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.2	5.8	PID ENDOTHELIN PATHWAY	Endothelins
0.2	43.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	19.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	8.6	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.2	2.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.2	6.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	5.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	5.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	1.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	4.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	1.7	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.2	7.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	7.3	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	2.5	PID INSULIN PATHWAY	Insulin Pathway
0.2	2.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.2	8.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	3.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.2	3.6	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	3.8	PID ARF 3PATHWAY	Arf1 pathway
0.2	6.9	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	3.7	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	0.4	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.2	5.9	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	8.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	2.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	2.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.2	2.9	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.2	9.5	PID CDC42 PATHWAY	CDC42 signaling events
0.2	3.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.2	0.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.2	3.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.2	1.8	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	3.5	PID RAS PATHWAY	Regulation of Ras family activation
0.1	1.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	3.3	PID ARF6 PATHWAY	Arf6 signaling events
0.1	0.9	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	2.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	5.1	PID ATR PATHWAY	ATR signaling pathway
0.1	3.2	PID MYC PATHWAY	C-MYC pathway
0.1	1.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	0.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	2.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.1	1.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	1.6	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	3.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	0.6	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	0.7	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	1.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	2.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	10.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.5	PID P73PATHWAY	p73 transcription factor network
0.1	0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.0	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	1.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	1.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	0.4	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	0.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	0.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	0.3	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	1.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.7	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.9	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.7	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.9	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	3.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.5	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.1	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	2.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.7	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.7	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.7	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.9	PID E2F PATHWAY	E2F transcription factor network

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.3	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.4	1.1	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.3	1.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.3	1.6	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3	4.5	GO:0015643	toxic substance binding(GO:0015643)
0.3	1.0	GO:0032810	sterol response element binding(GO:0032810)
0.2	1.0	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2	0.2	GO:0071209	U7 snRNA binding(GO:0071209)
0.2	0.6	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2	1.4	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.2	2.2	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.2	0.8	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.2	0.6	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.2	0.6	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2	0.8	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.2	1.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.2	1.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2	0.5	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.2	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2	0.8	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1	0.4	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.4	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1	0.4	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	0.6	GO:0033906	protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.1	0.4	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.1	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	1.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.6	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	1.0	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.1	1.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.7	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.3	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.1	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.1	1.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.4	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	0.3	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.3	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.3	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.9	GO:0050542	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.6	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.8	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.5	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.4	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	1.6	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.4	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	0.5	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.6	GO:0035174	histone serine kinase activity(GO:0035174)
0.1	0.3	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.6	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.4	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.7	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	1.0	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.2	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.1	1.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.1	0.2	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.1	0.5	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	1.7	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.2	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	1.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.5	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.5	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0	0.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.3	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.2	GO:0004532	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.2	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0	0.1	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.0	0.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0	0.3	GO:0035500	MH2 domain binding(GO:0035500)
0.0	1.8	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.9	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.7	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.3	GO:0050733	RS domain binding(GO:0050733)
0.0	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.5	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.2	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.8	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.5	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	3.7	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.7	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	1.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.2	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0034452	dynactin binding(GO:0034452)
0.0	0.3	GO:0097643	amylin receptor activity(GO:0097643)
0.0	0.2	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.3	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.6	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.5	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.5	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	1.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.4	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.4	GO:0046790	virion binding(GO:0046790)
0.0	3.2	GO:0016209	antioxidant activity(GO:0016209)
0.0	0.3	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.6	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.0	0.9	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0001031	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.0	0.5	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.3	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.4	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.2	GO:0045159	myosin II binding(GO:0045159)
0.0	2.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.5	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.3	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.8	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	0.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	1.0	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.4	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	0.1	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0	0.1	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	0.1	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.0	0.3	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	3.8	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	2.2	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.0	GO:0035473	lipase binding(GO:0035473)
0.0	0.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.5	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0031005	filamin binding(GO:0031005)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.2	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.4	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0	0.5	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	2.0	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.8	GO:0051287	NAD binding(GO:0051287)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.0	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.6	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	1.1	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.1	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.5	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0042019	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0	0.2	GO:0008417	fucosyltransferase activity(GO:0008417)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2	1.0	GO:0005726	perichromatin fibrils(GO:0005726)
0.2	0.8	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.1	1.2	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	0.8	GO:0070652	HAUS complex(GO:0070652)
0.1	1.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.5	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	2.0	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.8	GO:0031143	pseudopodium(GO:0031143)
0.0	0.7	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.9	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.5	GO:0008180	COP9 signalosome(GO:0008180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.3	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.3	GO:0004947	bradykinin receptor activity(GO:0004947)
0.1	2.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.8	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.3	GO:0032427	GBD domain binding(GO:0032427)
0.1	1.0	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.3	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	0.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	0.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.6	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0031716	calcitonin receptor binding(GO:0031716)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.9	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	46.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
1.6	41.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.5	27.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
1.4	71.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
1.3	25.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
1.2	1.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
1.0	19.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
1.0	17.0	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.0	23.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.9	36.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.9	3.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.9	0.9	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.9	0.9	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.9	12.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.9	24.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.8	16.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.8	52.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.8	11.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.8	2.4	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.8	7.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.8	17.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.8	18.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.7	4.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.7	15.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.7	8.9	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.7	43.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.7	15.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.6	6.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.6	19.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6	13.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.6	17.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5	6.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5	6.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.5	9.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.5	14.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.5	14.9	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.5	9.9	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5	8.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5	0.9	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.4	4.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4	0.9	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.4	8.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4	6.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.4	5.9	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.4	6.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	1.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	1.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.4	4.8	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.4	12.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.4	4.6	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3	10.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	8.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3	6.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.3	2.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	13.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.3	4.8	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.3	7.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3	42.9	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.3	5.8	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3	5.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	17.4	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.3	9.2	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.3	8.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.3	31.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	25.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.3	3.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	2.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3	3.8	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.3	2.8	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	4.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	5.0	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.2	19.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.2	5.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	10.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.2	5.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	1.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	4.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	1.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	3.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	3.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	1.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	6.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.2	2.7	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2	1.0	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.2	9.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	0.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	10.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.2	2.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	3.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	5.4	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.2	1.7	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.2	4.5	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.2	2.4	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2	3.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	0.8	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	2.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.9	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.1	2.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	2.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	5.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	5.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.0	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	0.7	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	4.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.2	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.1	2.0	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	7.8	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.1	1.4	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.1	2.8	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	8.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	2.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	0.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	1.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	7.8	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	3.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.8	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	2.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	0.9	REACTOME OPSINS	Genes involved in Opsins
0.1	2.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	8.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	2.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	0.9	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.6	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	2.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	0.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	1.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.4	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.1	0.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	4.3	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.6	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.8	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.9	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	6.2	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	2.4	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	2.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	3.8	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	1.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.9	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	1.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	4.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	2.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	12.8	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	1.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	2.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	1.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	2.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	8.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.9	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.9	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	2.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	1.3	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0048539	immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.1	0.3	GO:0008050	female courtship behavior(GO:0008050)
0.1	0.5	GO:0098707	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1	0.2	GO:0032641	negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1	0.6	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.1	1.5	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1	0.2	GO:0072658	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.2	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1	0.2	GO:0090149	synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.1	0.3	GO:0002803	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.2	GO:1904693	midbrain morphogenesis(GO:1904693)
0.0	0.4	GO:0030450	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0	0.3	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.3	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0044211	CTP salvage(GO:0044211)
0.0	0.2	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.3	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0048867	stem cell fate determination(GO:0048867)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.2	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.2	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.1	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
0.0	0.4	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.1	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.0	0.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.2	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.2	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0097107	postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0	0.1	GO:0010286	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.0	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0	0.2	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	48.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.4	3.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	4.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	10.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	4.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	2.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	3.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.1	4.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	1.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	2.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	3.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	3.9	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.7	2.2	GO:0070361	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.5	1.6	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4	3.1	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4	1.3	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
0.4	1.6	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.4	1.1	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.3	1.0	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3	2.0	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.3	0.3	GO:0004673	protein histidine kinase activity(GO:0004673)
0.3	1.2	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.3	1.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.3	0.8	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.3	2.4	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.3	1.3	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.3	0.8	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2	0.7	GO:0000035	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.2	1.8	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.2	1.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2	0.8	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.2	0.6	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
0.2	1.0	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2	0.6	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.2	0.6	GO:0098770	FBXO family protein binding(GO:0098770)
0.2	0.6	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2	0.9	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.2	3.0	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2	1.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.2	1.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.2	1.2	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.2	1.5	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	0.4	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.1	0.4	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	0.8	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.4	GO:0033149	FFAT motif binding(GO:0033149)
0.1	1.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	2.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	1.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.5	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.6	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	0.6	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	1.1	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.6	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	0.2	GO:0016936	galactoside binding(GO:0016936)
0.1	1.3	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.3	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.1	0.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.3	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	0.5	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	1.5	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.3	GO:0015235	cobalamin transporter activity(GO:0015235)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.3	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	1.0	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	1.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	0.3	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	2.0	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	1.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.3	GO:0070025	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.4	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.3	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1	0.2	GO:0043398	HLH domain binding(GO:0043398)
0.1	1.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.3	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	2.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.2	GO:0017130	poly(C) RNA binding(GO:0017130)
0.1	0.6	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1	1.7	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.5	GO:0043199	sulfate binding(GO:0043199)
0.1	0.3	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	1.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	0.2	GO:0015117	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1	0.4	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.3	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	3.0	GO:0030332	cyclin binding(GO:0030332)
0.1	1.7	GO:0030515	snoRNA binding(GO:0030515)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.5	GO:0005329	dopamine transmembrane transporter activity(GO:0005329) quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1	0.4	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1	1.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.5	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	0.3	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.4	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	0.4	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.2	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.1	1.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	1.7	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.4	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	0.2	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.1	0.4	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.6	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1	0.5	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	2.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.4	GO:1901612	cardiolipin binding(GO:1901612)
0.1	0.2	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.1	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	2.1	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.1	0.1	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.1	0.2	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.4	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.2	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.1	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	3.6	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.7	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.5	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0	0.7	GO:0016918	retinal binding(GO:0016918)
0.0	1.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.0	0.0	GO:0070888	E-box binding(GO:0070888)
0.0	0.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.4	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.2	GO:0019862	IgA binding(GO:0019862)
0.0	0.4	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.8	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.6	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.9	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.1	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0	0.3	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.2	GO:0030614	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0	0.1	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0	0.4	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.9	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.5	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.3	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.0	0.2	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.0	1.1	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.2	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.0	0.1	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.0	0.3	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.4	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.2	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.4	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.8	GO:0070840	dynein complex binding(GO:0070840)
0.0	1.0	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0	0.4	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.4	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.6	GO:0005536	glucose binding(GO:0005536)
0.0	0.8	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.0	0.3	GO:0097016	L27 domain binding(GO:0097016)
0.0	1.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.3	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.8	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0004084	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	0.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.3	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.5	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	1.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	0.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0	2.2	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.0	0.3	GO:0031386	protein tag(GO:0031386)
0.0	0.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0072349	modified amino acid transmembrane transporter activity(GO:0072349)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0	0.1	GO:0015926	glucosidase activity(GO:0015926)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.3	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.2	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	0.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.7	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.7	GO:0050661	NADP binding(GO:0050661)
0.0	0.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0031691	alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) platelet activating factor receptor binding(GO:0031859)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.3	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	0.4	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.1	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.8	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.9	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.5	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.4	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.0	0.1	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.0	GO:0032093	SAM domain binding(GO:0032093)
0.0	0.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	0.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0016901	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.1	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	10.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	12.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	4.7	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	2.0	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	4.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	0.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	2.0	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	1.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.2	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.6	2.9	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.3	1.0	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.3	0.9	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.3	0.8	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2	0.6	GO:1903288	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.1	1.7	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.8	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1	1.2	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1	0.4	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.1	1.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	1.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.4	GO:0006751	glutathione catabolic process(GO:0006751)
0.0	0.6	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.8	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.2	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	1.4	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3	1.3	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3	1.0	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.3	1.5	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2	1.0	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.2	0.9	GO:0038025	glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.2	1.5	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	10.0	GO:0003785	actin monomer binding(GO:0003785)
0.2	0.8	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.2	1.0	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2	1.8	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	0.7	GO:0004461	lactose synthase activity(GO:0004461)
0.2	0.5	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.2	0.5	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.2	2.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2	0.8	GO:0052841	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2	1.1	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.1	1.0	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1	0.5	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.8	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	1.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.5	GO:0005046	KDEL sequence binding(GO:0005046)
0.1	0.4	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.3	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.3	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	0.7	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.7	GO:0043426	MRF binding(GO:0043426)
0.1	0.3	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1	1.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.3	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.9	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	0.4	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	1.1	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.7	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.3	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	1.8	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.8	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.1	0.3	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.2	GO:0033149	FFAT motif binding(GO:0033149)
0.1	0.6	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.8	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	1.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.7	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	1.5	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1	0.6	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	0.7	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	2.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.6	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.7	GO:0008097	5S rRNA binding(GO:0008097)
0.1	0.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.7	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.7	GO:0034452	dynactin binding(GO:0034452)
0.1	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	1.8	GO:0015248	sterol transporter activity(GO:0015248)
0.1	1.1	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.8	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.0	1.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.1	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.0	0.9	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	1.1	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	0.5	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.7	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.7	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.7	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.2	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.2	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.1	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.1	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.0	0.2	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	1.7	GO:0005507	copper ion binding(GO:0005507)
0.0	0.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:1990380	Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	1.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.8	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.2	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	1.3	GO:0009055	electron carrier activity(GO:0009055)
0.0	0.7	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.9	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	2.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	2.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	2.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	3.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	1.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.9	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.3	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	3.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.5	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	1.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	14.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
1.2	38.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.4	21.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.3	5.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	20.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	0.9	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.2	1.2	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.2	12.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	5.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	2.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	14.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	3.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	2.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	2.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	4.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.6	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	3.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	2.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	5.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	3.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	5.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	2.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	2.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	1.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.7	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	2.1	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	1.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	3.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	2.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	3.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	0.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	2.4	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.1	2.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	4.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.1	0.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	3.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.8	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	3.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	1.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.8	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1	0.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	2.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	0.7	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.1	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.8	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	1.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	3.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.5	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	2.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	1.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.8	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.8	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.6	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	1.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	2.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	2.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	1.2	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	4.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	4.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.7	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	2.2	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	3.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.5	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	2.6	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.7	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.4	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME ORC1 REMOVAL FROM CHROMATIN	Genes involved in Orc1 removal from chromatin
0.0	1.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.3	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	1.7	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	4.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	5.0	PID AURORA B PATHWAY	Aurora B signaling
0.1	0.8	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	4.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.0	4.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.9	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.8	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.8	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	2.3	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	1.0	PID ATR PATHWAY	ATR signaling pathway
0.0	0.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.9	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.5	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.4	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.8	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	2.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.0	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.7	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.9	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.4	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.3	8.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	3.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	2.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	1.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	4.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	3.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	2.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	2.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	3.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	3.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	2.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	5.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	2.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	2.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	1.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.6	19.9	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
3.5	24.5	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.5	12.7	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
2.5	7.6	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
2.5	15.0	GO:1990254	keratin filament binding(GO:1990254)
2.4	14.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
2.1	8.3	GO:0004850	uridine phosphorylase activity(GO:0004850)
1.9	9.5	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
1.9	7.6	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
1.9	13.0	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
1.8	5.4	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
1.8	5.4	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.8	5.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.7	5.0	GO:0032090	Pyrin domain binding(GO:0032090)
1.6	13.2	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
1.6	4.7	GO:0030984	kininogen binding(GO:0030984)
1.6	6.2	GO:0030305	heparanase activity(GO:0030305)
1.5	4.6	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
1.5	9.2	GO:0038064	collagen receptor activity(GO:0038064)
1.5	13.6	GO:0032051	clathrin light chain binding(GO:0032051)
1.5	7.5	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
1.5	9.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
1.5	11.8	GO:0005497	androgen binding(GO:0005497)
1.4	8.6	GO:0003872	6-phosphofructokinase activity(GO:0003872)
1.4	4.2	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
1.4	5.6	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.4	13.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
1.4	12.2	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.3	4.0	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
1.3	2.6	GO:0048185	activin binding(GO:0048185)
1.3	7.7	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.3	3.8	GO:0030158	protein xylosyltransferase activity(GO:0030158)
1.2	4.9	GO:0031852	mu-type opioid receptor binding(GO:0031852)
1.2	3.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.2	4.7	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
1.2	7.0	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.2	4.6	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.1	16.7	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.1	1.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
1.1	4.3	GO:0008431	vitamin E binding(GO:0008431)
1.1	19.0	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
1.1	9.5	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
1.0	3.1	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.0	7.2	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.0	4.1	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
1.0	3.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.0	5.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
1.0	3.0	GO:0070006	metalloaminopeptidase activity(GO:0070006)
1.0	6.0	GO:1903135	cupric ion binding(GO:1903135)
1.0	1.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
1.0	5.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
1.0	3.0	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
1.0	6.8	GO:0047134	protein-disulfide reductase activity(GO:0047134)
1.0	8.7	GO:0048495	Roundabout binding(GO:0048495)
0.9	6.6	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.9	2.8	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.9	2.7	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.9	2.7	GO:0043398	HLH domain binding(GO:0043398)
0.9	1.8	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.9	2.7	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.9	0.9	GO:0004103	choline kinase activity(GO:0004103)
0.9	1.7	GO:0019534	toxin transporter activity(GO:0019534)
0.9	0.9	GO:0008131	primary amine oxidase activity(GO:0008131)
0.9	3.4	GO:0017089	glycolipid transporter activity(GO:0017089)
0.9	5.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.8	5.1	GO:0008948	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.8	4.1	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.8	1.6	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.8	5.7	GO:0070492	oligosaccharide binding(GO:0070492)
0.8	4.0	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.8	4.0	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.8	7.9	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.8	4.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.8	18.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.8	3.0	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.8	0.8	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.8	0.8	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.7	5.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.7	3.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.7	3.7	GO:0030348	syntaxin-3 binding(GO:0030348)
0.7	2.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.7	0.7	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.7	5.9	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.7	2.2	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.7	7.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7	5.9	GO:0005243	gap junction channel activity(GO:0005243)
0.7	5.8	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.7	4.3	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.7	4.3	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.7	6.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.7	3.5	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.7	1.4	GO:0070052	collagen V binding(GO:0070052)
0.7	2.1	GO:0070984	SET domain binding(GO:0070984)
0.7	9.0	GO:0038132	neuregulin binding(GO:0038132)
0.7	2.8	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.7	3.4	GO:0050815	phosphoserine binding(GO:0050815)
0.7	7.5	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.7	4.1	GO:0023025	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.7	2.7	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.7	8.0	GO:1990459	transferrin receptor binding(GO:1990459)
0.7	6.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.7	2.0	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.7	2.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.7	5.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.6	18.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.6	6.5	GO:0032036	myosin heavy chain binding(GO:0032036)
0.6	2.5	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.6	5.0	GO:0017166	vinculin binding(GO:0017166)
0.6	33.8	GO:0017080	sodium channel regulator activity(GO:0017080)
0.6	3.1	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.6	2.5	GO:0031685	adenosine receptor binding(GO:0031685)
0.6	7.4	GO:0031386	protein tag(GO:0031386)
0.6	0.6	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.6	1.8	GO:0019826	oxygen sensor activity(GO:0019826)
0.6	7.2	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.6	7.8	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.6	4.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.6	3.0	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.6	2.4	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.6	6.5	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.6	0.6	GO:0070404	NADH binding(GO:0070404)
0.6	5.3	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.6	5.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.6	7.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.6	2.3	GO:0042731	PH domain binding(GO:0042731)
0.6	4.6	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.6	5.8	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.6	3.4	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.6	2.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.6	2.3	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.6	9.0	GO:0004526	ribonuclease P activity(GO:0004526)
0.6	3.4	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.6	2.2	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.6	5.6	GO:0046870	cadmium ion binding(GO:0046870)
0.6	25.1	GO:0050699	WW domain binding(GO:0050699)
0.6	1.7	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.6	2.2	GO:0004743	pyruvate kinase activity(GO:0004743)
0.6	0.6	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.6	3.3	GO:0005499	vitamin D binding(GO:0005499)
0.6	2.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.6	1.7	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.5	1.6	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.5	3.3	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.5	1.6	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.5	8.7	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.5	2.2	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.5	9.2	GO:0015250	water channel activity(GO:0015250)
0.5	7.5	GO:0030280	structural constituent of epidermis(GO:0030280)
0.5	1.6	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.5	2.1	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.5	0.5	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5	6.3	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.5	14.7	GO:0030506	ankyrin binding(GO:0030506)
0.5	2.6	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.5	1.6	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.5	2.1	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5	9.9	GO:0005112	Notch binding(GO:0005112)
0.5	5.7	GO:0070300	phosphatidic acid binding(GO:0070300)
0.5	4.1	GO:0045545	syndecan binding(GO:0045545)
0.5	3.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.5	8.1	GO:0070411	I-SMAD binding(GO:0070411)
0.5	7.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.5	2.5	GO:0016015	morphogen activity(GO:0016015)
0.5	11.0	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.5	1.5	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.5	1.5	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.5	1.5	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.5	2.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.5	2.5	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.5	2.9	GO:0042296	ISG15 transferase activity(GO:0042296)
0.5	6.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.5	11.4	GO:0043236	laminin binding(GO:0043236)
0.5	1.4	GO:0032089	NACHT domain binding(GO:0032089)
0.5	4.7	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.5	3.7	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5	0.5	GO:0032810	sterol response element binding(GO:0032810)
0.5	2.8	GO:0046979	TAP2 binding(GO:0046979)
0.5	1.9	GO:0016842	amidine-lyase activity(GO:0016842)
0.5	1.9	GO:0043208	glycosphingolipid binding(GO:0043208)
0.5	1.9	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.5	1.8	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.5	0.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.5	1.4	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.5	1.4	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.5	1.4	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.5	0.5	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.4	0.4	GO:0016866	intramolecular transferase activity(GO:0016866)
0.4	17.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4	19.6	GO:0003785	actin monomer binding(GO:0003785)
0.4	2.7	GO:0015057	thrombin receptor activity(GO:0015057)
0.4	2.2	GO:0070568	guanylyltransferase activity(GO:0070568)
0.4	3.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.4	5.3	GO:0089720	caspase binding(GO:0089720)
0.4	2.6	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.4	0.4	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.4	2.2	GO:0050436	microfibril binding(GO:0050436)
0.4	2.6	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.4	0.4	GO:0033265	choline binding(GO:0033265)
0.4	1.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.4	3.0	GO:0015288	porin activity(GO:0015288)
0.4	1.7	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.4	4.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4	7.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.4	6.4	GO:0048018	receptor agonist activity(GO:0048018)
0.4	1.3	GO:0035671	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.4	1.3	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.4	1.3	GO:0003883	CTP synthase activity(GO:0003883)
0.4	1.3	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.4	1.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.4	1.2	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4	2.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.4	0.4	GO:0001968	fibronectin binding(GO:0001968)
0.4	3.7	GO:0043426	MRF binding(GO:0043426)
0.4	1.2	GO:0004947	bradykinin receptor activity(GO:0004947)
0.4	6.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.4	1.6	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.4	1.6	GO:0004074	biliverdin reductase activity(GO:0004074)
0.4	1.2	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.4	11.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.4	44.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.4	2.4	GO:0008443	phosphofructokinase activity(GO:0008443)
0.4	1.2	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.4	0.4	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.4	0.8	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.4	1.2	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.4	2.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.4	1.2	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.4	16.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.4	1.6	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.4	2.3	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.4	0.4	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.4	1.1	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4	3.8	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.4	1.5	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.4	1.1	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.4	5.6	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.4	28.7	GO:0019003	GDP binding(GO:0019003)
0.4	0.4	GO:1990239	steroid hormone binding(GO:1990239)
0.4	0.4	GO:0042806	fucose binding(GO:0042806)
0.4	3.3	GO:0004969	histamine receptor activity(GO:0004969)
0.4	0.7	GO:0001222	transcription corepressor binding(GO:0001222)
0.4	2.6	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4	1.1	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4	5.1	GO:0031489	myosin V binding(GO:0031489)
0.4	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.4	2.2	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4	5.0	GO:0017049	GTP-Rho binding(GO:0017049)
0.4	1.4	GO:0038025	reelin receptor activity(GO:0038025)
0.4	0.7	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.4	0.4	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.4	0.4	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.4	1.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3	3.5	GO:0015266	protein channel activity(GO:0015266)
0.3	0.7	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.3	0.7	GO:0070697	activin receptor binding(GO:0070697)
0.3	1.4	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3	0.7	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3	6.1	GO:0044548	S100 protein binding(GO:0044548)
0.3	1.4	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.3	1.0	GO:0046625	sphingolipid binding(GO:0046625)
0.3	0.3	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.3	3.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.3	2.3	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.3	1.7	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.3	2.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.3	1.6	GO:0015295	solute:proton symporter activity(GO:0015295)
0.3	1.0	GO:0050610	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.3	1.6	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3	2.3	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.3	8.0	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.3	5.4	GO:0008432	JUN kinase binding(GO:0008432)
0.3	2.9	GO:0022840	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3	2.5	GO:0008565	protein transporter activity(GO:0008565)
0.3	0.9	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.3	4.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.3	3.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.3	2.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.3	0.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	1.9	GO:0016416	O-palmitoyltransferase activity(GO:0016416)
0.3	3.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.3	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.3	0.6	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.3	0.3	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.3	1.8	GO:0039552	RIG-I binding(GO:0039552)
0.3	1.2	GO:0004348	glucosylceramidase activity(GO:0004348)
0.3	4.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.3	1.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.3	4.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.3	4.8	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3	2.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3	2.1	GO:0030911	TPR domain binding(GO:0030911)
0.3	0.9	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.3	0.6	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3	0.6	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.3	1.8	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.3	1.2	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.3	1.8	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3	1.8	GO:0043532	angiostatin binding(GO:0043532)
0.3	1.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3	1.2	GO:0001855	complement component C4b binding(GO:0001855)
0.3	5.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.3	0.3	GO:0036033	mediator complex binding(GO:0036033)
0.3	1.2	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.3	1.2	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.3	2.3	GO:0004000	adenosine deaminase activity(GO:0004000)
0.3	8.7	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3	0.9	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.3	1.4	GO:0004882	androgen receptor activity(GO:0004882)
0.3	0.3	GO:0016595	glutamate binding(GO:0016595)
0.3	1.7	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3	6.0	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3	0.8	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.3	1.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.3	0.8	GO:0016531	copper chaperone activity(GO:0016531)
0.3	2.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.3	0.8	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.3	44.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.3	1.7	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3	1.1	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.3	9.3	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.3	0.3	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.3	2.5	GO:0008158	hedgehog receptor activity(GO:0008158)
0.3	1.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.3	1.6	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3	4.6	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.3	1.6	GO:0001849	complement component C1q binding(GO:0001849)
0.3	1.6	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.3	4.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.3	4.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.3	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3	1.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3	0.8	GO:0004766	spermidine synthase activity(GO:0004766)
0.3	3.4	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3	0.8	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.3	0.3	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.3	4.1	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.3	0.8	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	3.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.3	0.3	GO:0032767	copper-dependent protein binding(GO:0032767)
0.3	2.5	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3	0.5	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3	4.8	GO:0008327	methyl-CpG binding(GO:0008327)
0.3	0.5	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.3	1.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.3	1.8	GO:0030274	LIM domain binding(GO:0030274)
0.2	0.2	GO:0031433	telethonin binding(GO:0031433)
0.2	2.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.2	1.2	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.2	3.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.2	0.7	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.2	0.7	GO:0031877	somatostatin receptor binding(GO:0031877)
0.2	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.2	1.7	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.2	1.5	GO:0031705	bombesin receptor binding(GO:0031705)
0.2	8.0	GO:0000146	microfilament motor activity(GO:0000146)
0.2	1.9	GO:0004111	creatine kinase activity(GO:0004111)
0.2	1.4	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.2	5.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2	0.7	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.2	0.9	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2	0.7	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.2	0.7	GO:0051766	inositol trisphosphate kinase activity(GO:0051766)
0.2	0.5	GO:0019959	interleukin-8 binding(GO:0019959)
0.2	1.4	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2	2.8	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2	1.2	GO:0004645	phosphorylase activity(GO:0004645)
0.2	5.1	GO:0000339	RNA cap binding(GO:0000339)
0.2	1.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2	2.3	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.2	10.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.2	2.9	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2	0.2	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2	0.7	GO:0034511	U3 snoRNA binding(GO:0034511)
0.2	1.4	GO:0052656	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2	3.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.2	1.8	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	55.2	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	0.4	GO:0003678	DNA helicase activity(GO:0003678)
0.2	2.9	GO:0004985	opioid receptor activity(GO:0004985)
0.2	0.4	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2	1.5	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2	5.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	3.9	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	1.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.2	3.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2	0.4	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.2	0.8	GO:0004132	dCMP deaminase activity(GO:0004132)
0.2	2.5	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.2	0.8	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2	1.5	GO:0032027	myosin light chain binding(GO:0032027)
0.2	1.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.2	0.6	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.2	7.2	GO:0019894	kinesin binding(GO:0019894)
0.2	1.0	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.2	1.0	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.2	5.7	GO:0071889	14-3-3 protein binding(GO:0071889)
0.2	0.6	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.2	0.6	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2	0.2	GO:0005119	smoothened binding(GO:0005119)
0.2	0.6	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.2	1.0	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.2	1.6	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.2	4.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	0.8	GO:0048039	ubiquinone binding(GO:0048039)
0.2	0.6	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2	0.6	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2	1.2	GO:0008201	heparin binding(GO:0008201)
0.2	3.7	GO:0051400	BH domain binding(GO:0051400)
0.2	0.6	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.2	4.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.2	5.0	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.2	0.4	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2	8.1	GO:0061650	ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2	0.6	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.2	5.4	GO:0017022	myosin binding(GO:0017022)
0.2	0.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2	0.6	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.2	0.6	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2	0.4	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.2	14.4	GO:0032947	protein complex scaffold(GO:0032947)
0.2	0.9	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.2	13.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	0.2	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2	0.9	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2	0.7	GO:0008410	CoA-transferase activity(GO:0008410)
0.2	2.0	GO:0017070	U6 snRNA binding(GO:0017070)
0.2	0.5	GO:0051373	FATZ binding(GO:0051373)
0.2	1.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2	0.4	GO:0017129	triglyceride binding(GO:0017129)
0.2	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.2	6.7	GO:0017137	Rab GTPase binding(GO:0017137)
0.2	0.2	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2	5.8	GO:0004385	guanylate kinase activity(GO:0004385)
0.2	0.2	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2	7.7	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.2	0.5	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.2	0.9	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2	0.4	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.2	1.0	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2	0.2	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2	0.3	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.2	1.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2	0.5	GO:0004962	endothelin receptor activity(GO:0004962)
0.2	0.7	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2	0.5	GO:0008172	S-methyltransferase activity(GO:0008172)
0.2	1.4	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.2	0.7	GO:0004461	lactose synthase activity(GO:0004461)
0.2	0.5	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.2	0.3	GO:0005047	signal recognition particle binding(GO:0005047)
0.2	0.2	GO:0004966	galanin receptor activity(GO:0004966)
0.2	1.7	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2	0.7	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	0.2	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2	1.0	GO:1990446	U1 snRNP binding(GO:1990446)
0.2	2.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	1.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2	4.6	GO:0017025	TBP-class protein binding(GO:0017025)
0.2	1.0	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
0.2	1.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.2	1.8	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2	0.7	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2	52.3	GO:0045296	cadherin binding(GO:0045296)
0.2	1.9	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.2	0.6	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2	0.2	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2	0.2	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.2	0.3	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.2	0.3	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.2	7.6	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2	1.3	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2	0.6	GO:0016882	cyclo-ligase activity(GO:0016882)
0.2	1.3	GO:0042301	phosphate ion binding(GO:0042301)
0.2	0.8	GO:0047820	D-glutamate cyclase activity(GO:0047820)
0.2	0.3	GO:0035198	miRNA binding(GO:0035198)
0.2	1.4	GO:0008199	ferric iron binding(GO:0008199)
0.2	0.5	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.2	0.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.2	0.5	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.2	0.3	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.2	0.2	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.2	0.5	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.4	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.1	0.7	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1	0.4	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	1.5	GO:0035240	dopamine binding(GO:0035240)
0.1	2.0	GO:0070402	NADPH binding(GO:0070402)
0.1	2.6	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.4	GO:0004775	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	0.6	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	0.4	GO:0004730	pseudouridylate synthase activity(GO:0004730)
0.1	0.3	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.1	0.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1	0.4	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	1.1	GO:0003682	chromatin binding(GO:0003682)
0.1	0.4	GO:0005549	odorant binding(GO:0005549)
0.1	2.6	GO:0019956	chemokine binding(GO:0019956)
0.1	3.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	5.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	0.4	GO:0032427	GBD domain binding(GO:0032427)
0.1	0.1	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.1	2.0	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	2.6	GO:0010857	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	1.2	GO:0048019	receptor antagonist activity(GO:0048019)
0.1	1.8	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.5	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.5	GO:0016499	orexin receptor activity(GO:0016499)
0.1	0.6	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	4.5	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.1	1.0	GO:0008301	DNA binding, bending(GO:0008301)
0.1	1.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.3	GO:0034452	dynactin binding(GO:0034452)
0.1	0.6	GO:0036122	BMP binding(GO:0036122)
0.1	0.9	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	0.6	GO:0051425	PTB domain binding(GO:0051425)
0.1	1.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	1.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.6	GO:0048156	tau protein binding(GO:0048156)
0.1	0.6	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	0.5	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.1	0.7	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	0.4	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.6	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.1	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1	2.9	GO:0005272	sodium channel activity(GO:0005272)
0.1	1.9	GO:0097602	cullin family protein binding(GO:0097602)
0.1	2.5	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	0.6	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1	1.0	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.7	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.1	0.4	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.1	1.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.1	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.1	0.9	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1	0.4	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.1	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.5	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	1.1	GO:0043621	protein self-association(GO:0043621)
0.1	3.0	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.1	GO:0004040	amidase activity(GO:0004040)
0.1	0.2	GO:1901612	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1	1.4	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	5.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.5	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.1	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1	2.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	0.4	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.4	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	2.0	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.1	2.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.3	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.3	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	2.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.5	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	0.2	GO:0005080	protein kinase C binding(GO:0005080)
0.1	1.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	1.4	GO:0019201	nucleotide kinase activity(GO:0019201)
0.1	0.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.1	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1	0.3	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.5	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.2	GO:0005113	patched binding(GO:0005113)
0.1	0.3	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1	0.3	GO:0004608	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	1.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.1	0.6	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.5	GO:0002046	opsin binding(GO:0002046)
0.1	0.4	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	2.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.4	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	3.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.2	GO:0008252	nucleotidase activity(GO:0008252)
0.1	4.0	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.1	1.9	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.3	GO:0002113	interleukin-33 binding(GO:0002113)
0.1	0.3	GO:0004913	interleukin-4 receptor activity(GO:0004913)
0.1	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.1	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.1	1.9	GO:0000217	DNA secondary structure binding(GO:0000217)
0.1	0.3	GO:0030957	Tat protein binding(GO:0030957)
0.1	1.3	GO:0009881	photoreceptor activity(GO:0009881)
0.1	0.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.2	GO:0017018	myosin phosphatase activity(GO:0017018)
0.1	3.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	1.5	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.3	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.3	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.1	1.1	GO:0019206	nucleoside kinase activity(GO:0019206)
0.1	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.1	1.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	17.0	GO:0003924	GTPase activity(GO:0003924)
0.1	0.4	GO:0043295	glutathione binding(GO:0043295)
0.1	2.7	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.8	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	0.4	GO:0046527	glucosyltransferase activity(GO:0046527)
0.1	9.7	GO:0005178	integrin binding(GO:0005178)
0.1	0.5	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.6	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1	0.4	GO:0015350	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.9	GO:0030883	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1	0.5	GO:0000182	rDNA binding(GO:0000182)
0.1	0.5	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.1	3.7	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	1.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.4	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	2.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	35.6	GO:0005198	structural molecule activity(GO:0005198)
0.1	0.4	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	1.5	GO:0070182	DNA polymerase binding(GO:0070182)
0.1	0.3	GO:0031493	nucleosomal histone binding(GO:0031493)
0.1	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.3	GO:0003796	lysozyme activity(GO:0003796)
0.1	1.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	3.3	GO:0042379	chemokine receptor binding(GO:0042379)
0.1	2.5	GO:0070888	E-box binding(GO:0070888)
0.1	0.3	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1	1.5	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.2	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.1	2.8	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	2.5	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.1	1.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	0.5	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.1	0.2	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	0.4	GO:0030332	cyclin binding(GO:0030332)
0.1	0.1	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	2.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	0.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	2.0	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	0.2	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	0.2	GO:0043531	ADP binding(GO:0043531)
0.1	0.5	GO:0070513	death domain binding(GO:0070513)
0.1	1.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	0.3	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	0.2	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.1	0.1	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1	0.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	1.7	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1	1.5	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.1	0.2	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	0.1	GO:0071813	lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.1	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.1	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1	0.7	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.6	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	1.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.3	GO:0035939	microsatellite binding(GO:0035939)
0.1	1.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	3.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.1	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1	0.6	GO:0030276	clathrin binding(GO:0030276)
0.1	2.7	GO:0050681	androgen receptor binding(GO:0050681)
0.1	0.3	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.1	GO:0005536	glucose binding(GO:0005536)
0.1	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.7	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	0.1	GO:0008494	translation activator activity(GO:0008494)
0.1	0.2	GO:0070878	primary miRNA binding(GO:0070878)
0.1	0.1	GO:0030547	receptor inhibitor activity(GO:0030547)
0.1	0.8	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.1	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	1.7	GO:0008066	glutamate receptor activity(GO:0008066)
0.1	0.2	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.1	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	1.5	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.1	0.9	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	0.3	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	0.7	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.1	0.3	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.2	GO:0001181	transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1	0.5	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.2	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1	5.7	GO:0051015	actin filament binding(GO:0051015)
0.1	3.8	GO:0004175	endopeptidase activity(GO:0004175)
0.1	0.1	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.1	0.3	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.2	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.3	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.1	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	1.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.6	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	23.4	GO:0005509	calcium ion binding(GO:0005509)
0.1	0.2	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.1	0.2	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.1	0.1	GO:0010181	FMN binding(GO:0010181)
0.1	0.7	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	0.2	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1	1.1	GO:0030553	cGMP binding(GO:0030553)
0.1	0.3	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1	0.2	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	3.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.2	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	1.6	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.6	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.4	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.4	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	3.4	GO:0044325	ion channel binding(GO:0044325)
0.0	0.4	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.0	0.0	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0	0.1	GO:0016429	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	1.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.7	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.2	GO:1904492	Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.8	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	2.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.4	GO:0015631	tubulin binding(GO:0015631)
0.0	0.0	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.5	GO:0035258	steroid hormone receptor binding(GO:0035258)
0.0	0.1	GO:0015375	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) glycine:sodium symporter activity(GO:0015375)
0.0	1.6	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.4	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0005165	neurotrophin receptor binding(GO:0005165)
0.0	1.6	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.3	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	0.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	1.9	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.0	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0	0.5	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.0	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	6.8	GO:0030695	GTPase regulator activity(GO:0030695)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.0	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.1	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0	0.2	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.0	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.4	GO:0031267	small GTPase binding(GO:0031267)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.0	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.0	0.2	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.1	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.9	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.8	4.0	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.7	2.9	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.6	2.4	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.6	1.7	GO:0008859	exoribonuclease II activity(GO:0008859)
0.6	2.2	GO:0035473	lipase binding(GO:0035473)
0.5	1.6	GO:0052595	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.5	1.5	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.5	0.5	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.5	1.9	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4	1.7	GO:0019862	IgA binding(GO:0019862)
0.4	3.3	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.4	2.9	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.4	1.2	GO:0046921	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.4	1.9	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.4	4.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.4	1.1	GO:1902122	chenodeoxycholic acid binding(GO:1902122)
0.4	0.4	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4	1.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4	2.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.3	1.4	GO:0032145	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3	1.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.3	3.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.3	3.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.3	1.3	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.3	1.2	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.3	1.2	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3	1.8	GO:0045159	myosin II binding(GO:0045159)
0.3	1.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.3	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3	0.9	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.3	1.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	2.6	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3	0.3	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.3	0.8	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.3	1.9	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.3	1.9	GO:0016015	morphogen activity(GO:0016015)
0.3	0.8	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.3	1.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3	2.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.2	0.7	GO:0032184	SUMO polymer binding(GO:0032184)
0.2	2.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.2	1.2	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2	0.7	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2	3.7	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2	0.7	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.2	4.3	GO:0051787	misfolded protein binding(GO:0051787)
0.2	1.9	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2	1.3	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.2	1.1	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2	0.6	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.2	1.2	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2	0.6	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2	1.4	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2	0.6	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2	1.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.2	1.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.2	0.8	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.2	1.8	GO:0032190	acrosin binding(GO:0032190)
0.2	0.8	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.2	9.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.2	1.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	18.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	0.9	GO:0004359	glutaminase activity(GO:0004359)
0.2	1.7	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.5	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2	0.3	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2	0.5	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.2	0.5	GO:0016708	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.2	0.9	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2	0.8	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	0.6	GO:0017040	ceramidase activity(GO:0017040)
0.2	0.5	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2	2.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2	0.5	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.4	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1	1.6	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1	2.0	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.9	GO:0044594	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.4	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.6	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.1	0.6	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	1.5	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.4	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.1	0.5	GO:0038025	reelin receptor activity(GO:0038025)
0.1	0.4	GO:0070362	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1	0.8	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.5	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.1	0.4	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1	0.4	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	2.3	GO:0015923	mannosidase activity(GO:0015923)
0.1	0.4	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1	0.6	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.9	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	1.7	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	0.7	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.4	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.5	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	0.9	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.3	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.5	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.3	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	1.0	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1	0.8	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	1.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.8	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.8	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.1	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	2.5	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	8.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.5	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.1	0.4	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.8	GO:0032052	bile acid binding(GO:0032052)
0.1	0.6	GO:0048039	ubiquinone binding(GO:0048039)
0.1	1.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.3	GO:0005497	androgen binding(GO:0005497)
0.1	1.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	0.6	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	0.8	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	0.1	GO:0043566	structure-specific DNA binding(GO:0043566)
0.1	0.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.5	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1	0.2	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1	0.5	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.1	0.7	GO:0034235	GPI anchor binding(GO:0034235)
0.1	0.4	GO:0005124	scavenger receptor binding(GO:0005124)
0.1	0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.4	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	0.4	GO:0031716	calcitonin receptor binding(GO:0031716)
0.1	2.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.2	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.4	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.3	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.3	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.4	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	0.4	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.6	GO:0016405	CoA-ligase activity(GO:0016405)
0.1	0.3	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.3	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.8	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	1.6	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.2	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.1	0.2	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1	0.3	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1	0.9	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.5	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	0.7	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.3	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	0.4	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.2	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.1	0.2	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	1.0	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.3	GO:0015265	urea channel activity(GO:0015265)
0.1	0.3	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.3	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	1.5	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.6	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.1	1.8	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.5	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.6	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.8	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.3	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.1	0.3	GO:0008410	CoA-transferase activity(GO:0008410)
0.1	0.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.7	GO:0042731	PH domain binding(GO:0042731)
0.1	1.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.2	GO:0032093	SAM domain binding(GO:0032093)
0.1	2.1	GO:0042605	peptide antigen binding(GO:0042605)
0.1	1.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.3	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.3	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	1.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.6	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.1	0.2	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.3	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	0.4	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.2	GO:0017129	triglyceride binding(GO:0017129)
0.1	1.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.2	GO:0031711	angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.1	2.0	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	0.2	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	3.6	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.3	GO:0017018	myosin phosphatase activity(GO:0017018)
0.1	0.2	GO:0004020	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1	0.4	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.5	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.1	1.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.9	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.1	0.5	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.4	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	1.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.9	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1	0.2	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	0.3	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.1	1.5	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.3	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	2.1	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.7	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.3	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.5	GO:0043426	MRF binding(GO:0043426)
0.1	0.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.5	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	1.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.2	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	1.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.3	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.1	1.0	GO:0031005	filamin binding(GO:0031005)
0.1	0.5	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	1.0	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.1	0.2	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.1	0.5	GO:0039706	co-receptor binding(GO:0039706)
0.1	0.9	GO:0008494	translation activator activity(GO:0008494)
0.1	1.0	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.1	GO:0070052	collagen V binding(GO:0070052)
0.1	0.3	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1	0.5	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.8	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.6	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.5	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	1.3	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.2	GO:0030172	troponin C binding(GO:0030172)
0.0	1.9	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	1.0	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	1.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.9	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.7	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.3	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.2	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0	0.3	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.3	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.9	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.9	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.8	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.1	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.0	0.6	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	1.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.8	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	3.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0031545	peptidyl-proline dioxygenase activity(GO:0031543) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.5	GO:0046870	cadmium ion binding(GO:0046870)
0.0	2.6	GO:0019843	rRNA binding(GO:0019843)
0.0	1.2	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.3	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.6	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.2	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.4	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0	0.1	GO:0099609	microtubule lateral binding(GO:0099609)
0.0	0.2	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.2	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0	0.9	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0	0.2	GO:0052828	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0	0.5	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.2	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	1.6	GO:0005518	collagen binding(GO:0005518)
0.0	0.3	GO:0043022	ribosome binding(GO:0043022)
0.0	0.7	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.7	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	4.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.9	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	1.2	GO:0005507	copper ion binding(GO:0005507)
0.0	0.2	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	1.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	1.1	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	1.3	GO:0038024	cargo receptor activity(GO:0038024)
0.0	0.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0	0.1	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.0	GO:0016211	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.0	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0	0.2	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	2.0	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.3	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.5	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0	0.7	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0	0.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.1	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	1.2	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.0	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	7.2	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.3	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.2	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.1	GO:0070404	NADH binding(GO:0070404)
0.0	0.0	GO:0070728	leucine binding(GO:0070728)
0.0	0.1	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.0	0.0	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.3	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0047708	biotinidase activity(GO:0047708)
0.0	0.2	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:1904047	S-adenosyl-L-methionine binding(GO:1904047)
0.0	0.0	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.3	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.3	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0	0.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.5	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.0	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0	5.5	GO:0003779	actin binding(GO:0003779)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	1.2	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.1	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.0	0.1	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.0	0.1	GO:0004882	androgen receptor activity(GO:0004882)
0.0	0.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	0.6	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.2	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.1	GO:0003774	motor activity(GO:0003774)
0.0	0.0	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.0	GO:0052796	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	2.8	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	4.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	1.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.8	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	1.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	2.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	1.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.0	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.6	2.5	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.6	1.7	GO:0033823	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5	2.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.5	2.4	GO:0034597	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.5	1.4	GO:0035501	MH1 domain binding(GO:0035501)
0.4	1.3	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.4	1.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4	1.3	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.4	1.5	GO:0048763	HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.3	0.8	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.3	1.6	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.3	0.8	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2	1.7	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.2	1.2	GO:0030348	syntaxin-3 binding(GO:0030348)
0.2	0.2	GO:0042923	neuropeptide binding(GO:0042923)
0.2	0.6	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2	1.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.8	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	5.4	GO:0005523	tropomyosin binding(GO:0005523)
0.2	1.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	0.7	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	0.9	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.6	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.8	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.7	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	0.5	GO:0047718	enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1	1.6	GO:0015248	sterol transporter activity(GO:0015248)
0.1	1.6	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	1.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.7	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	10.5	GO:0005518	collagen binding(GO:0005518)
0.1	1.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.2	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1	0.6	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.5	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	0.3	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.9	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.9	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.4	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1	0.6	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.3	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	1.9	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.6	GO:0046625	sphingolipid binding(GO:0046625)
0.1	1.6	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.5	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.7	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.3	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.1	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.7	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.2	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.1	1.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	1.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.3	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1	2.0	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	2.6	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.3	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1	1.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.6	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	3.2	GO:0015485	cholesterol binding(GO:0015485)
0.1	0.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	1.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	1.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.3	GO:0097643	amylin receptor activity(GO:0097643)
0.1	1.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.8	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.3	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.7	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	4.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	1.0	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.0	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	1.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	1.3	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.4	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.0	0.2	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.2	GO:0031716	calcitonin receptor binding(GO:0031716)
0.0	0.6	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.8	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	1.6	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.4	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.4	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.1	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.6	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	1.3	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0	0.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.5	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0	1.0	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.2	GO:0042731	PH domain binding(GO:0042731)
0.0	0.4	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	2.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0004882	androgen receptor activity(GO:0004882)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.5	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	2.3	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.2	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0016595	glutamate binding(GO:0016595)
0.0	2.3	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.6	GO:0030971	receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	12.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
1.2	3.5	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.1	9.8	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
1.0	3.1	GO:1904395	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.8	1.7	GO:1990523	bone regeneration(GO:1990523)
0.7	2.0	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.7	2.0	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6	1.9	GO:0021569	rhombomere 3 development(GO:0021569)
0.5	2.1	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.5	1.5	GO:0019417	sulfur oxidation(GO:0019417)
0.5	0.5	GO:0043300	regulation of myeloid leukocyte mediated immunity(GO:0002886) regulation of leukocyte degranulation(GO:0043300)
0.5	1.8	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.4	1.3	GO:0099552	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.4	1.1	GO:0019482	purine nucleobase catabolic process(GO:0006145) beta-alanine metabolic process(GO:0019482)
0.3	2.4	GO:0023021	termination of signal transduction(GO:0023021)
0.3	1.0	GO:1990108	protein linear deubiquitination(GO:1990108)
0.3	1.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.3	2.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.3	0.9	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.3	1.2	GO:0052330	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of type B pancreatic cell development(GO:2000078)
0.3	1.4	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3	3.1	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.3	0.8	GO:0072019	carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.3	0.8	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2	1.5	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	0.9	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.2	0.6	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	1.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2	0.8	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2	0.6	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.2	0.6	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2	2.9	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	0.8	GO:0072144	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.2	1.5	GO:0015727	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.2	0.6	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.2	0.6	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.2	0.5	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.2	0.6	GO:0051866	general adaptation syndrome(GO:0051866)
0.1	1.0	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.1	2.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	1.0	GO:0051126	negative regulation of actin nucleation(GO:0051126)
0.1	0.4	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1	2.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.1	GO:0045794	negative regulation of cell volume(GO:0045794)
0.1	0.9	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1	0.3	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	0.8	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	3.3	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.1	0.4	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1	0.4	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.1	3.9	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	0.2	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of leukocyte degranulation(GO:0043302)
0.1	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.3	GO:0070541	response to platinum ion(GO:0070541)
0.1	0.3	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.1	0.5	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.1	0.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.3	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1	2.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.3	GO:0000189	MAPK import into nucleus(GO:0000189)
0.1	0.7	GO:0042908	xenobiotic transport(GO:0042908)
0.1	1.6	GO:0015800	acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.1	0.9	GO:0045116	protein neddylation(GO:0045116)
0.1	0.6	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.5	GO:0042262	DNA protection(GO:0042262)
0.0	0.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.8	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.7	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.2	GO:0034344	microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.3	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:2001187	CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0	0.7	GO:0050872	white fat cell differentiation(GO:0050872) cellular response to lithium ion(GO:0071285)
0.0	0.9	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.5	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.4	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.2	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	1.2	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.4	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	1.1	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0010157	response to chlorate(GO:0010157)
0.0	1.6	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.3	GO:2001300	lipoxin metabolic process(GO:2001300)
0.0	1.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	1.2	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.2	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.8	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:1903597	negative regulation of gap junction assembly(GO:1903597)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0010564	regulation of cell cycle process(GO:0010564)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.6	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.4	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.2	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.5	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.3	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	1.3	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.0	GO:0043400	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.0	0.1	GO:1903960	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) plasma membrane long-chain fatty acid transport(GO:0015911) negative regulation of anion transmembrane transport(GO:1903960)
0.0	0.8	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.2	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.3	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0	1.3	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	5.3	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	3.5	GO:0015992	proton transport(GO:0015992)
0.0	0.9	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.4	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.2	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.0	0.2	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
0.0	0.7	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.1	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.9	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.4	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	1.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.2	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.5	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.1	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	0.2	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.4	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.1	GO:0023019	signal transduction involved in regulation of gene expression(GO:0023019)
0.0	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.2	GO:0001502	cartilage condensation(GO:0001502)
0.0	2.4	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.4	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	19.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.9	8.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.6	9.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.6	5.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.5	8.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.5	12.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	5.9	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.4	7.4	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.4	7.2	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.4	8.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.4	4.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.3	7.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.3	8.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	12.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.3	6.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	18.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	11.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	2.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3	10.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3	7.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.3	7.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.3	6.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.3	2.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2	4.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.2	6.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	6.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	5.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.2	4.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	4.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.2	2.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.2	3.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.2	4.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2	0.2	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.2	5.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.2	1.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.2	2.7	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	6.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	4.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2	1.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.2	3.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	2.9	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	4.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	3.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	5.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	5.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	3.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	2.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	2.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	2.6	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	2.2	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.1	1.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	3.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	4.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.4	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.1	3.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	6.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	7.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	4.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	0.4	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.1	15.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	3.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	0.9	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	8.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.6	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	2.6	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1	0.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	0.8	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	5.7	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.1	1.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	8.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	1.4	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	2.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	3.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	0.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	2.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	1.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.8	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	2.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	1.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.4	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	3.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	1.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	8.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.8	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.6	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	1.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	3.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.8	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.5	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.0	0.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	1.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.8	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	1.0	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	1.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	11.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	3.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	2.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	3.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	1.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	7.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	2.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	0.8	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	2.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	1.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	0.5	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.8	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	0.9	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	4.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	2.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.8	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	1.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	3.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.5	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	1.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.7	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	11.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	10.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	2.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	4.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	3.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.4	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.9	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	1.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.7	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	15.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	5.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	6.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	2.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	3.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	2.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	4.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	0.9	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	2.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.8	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	0.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	1.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	2.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.6	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	5.9	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.8	9.8	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7	2.2	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.7	2.0	GO:0032089	NACHT domain binding(GO:0032089)
0.5	2.5	GO:0050436	microfibril binding(GO:0050436)
0.3	1.0	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3	0.9	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.3	1.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	1.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	0.7	GO:0002113	interleukin-33 binding(GO:0002113)
0.2	1.4	GO:0004882	androgen receptor activity(GO:0004882)
0.2	0.9	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.2	0.6	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.2	0.6	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.8	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2	0.6	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2	0.9	GO:0016403	dimethylargininase activity(GO:0016403)
0.2	0.9	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2	0.6	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	0.8	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2	0.8	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	0.6	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	3.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.8	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.9	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.6	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1	0.6	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1	0.6	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	0.3	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.1	0.8	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	0.3	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.8	GO:0030172	troponin C binding(GO:0030172)
0.1	1.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.6	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.9	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	2.1	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	0.7	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1	0.6	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	6.6	GO:0019843	rRNA binding(GO:0019843)
0.1	0.5	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	1.0	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.5	GO:1990254	keratin filament binding(GO:1990254)
0.1	0.3	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1	2.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.6	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.5	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.8	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.2	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	1.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.1	0.2	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	0.2	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.2	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.2	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1	1.7	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.2	GO:0052895	norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.1	1.0	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.1	0.3	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.4	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.8	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.2	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.2	GO:0015616	DNA translocase activity(GO:0015616)
0.1	0.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.5	GO:0051425	PTB domain binding(GO:0051425)
0.1	0.3	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0	1.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.3	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	0.3	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.0	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.2	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.3	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	1.0	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.0	0.3	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.0	0.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.2	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.3	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.1	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.2	GO:0098821	inhibin binding(GO:0034711) BMP receptor activity(GO:0098821)
0.0	0.4	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.6	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.3	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0004962	endothelin receptor activity(GO:0004962)
0.0	0.4	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0005119	smoothened binding(GO:0005119)
0.0	0.5	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0	1.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.7	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.1	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.0	0.1	GO:0070697	activin receptor binding(GO:0070697)
0.0	0.2	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.0	0.5	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.3	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.4	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.0	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	1.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	1.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0	0.1	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.0	0.8	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.4	GO:0008494	translation activator activity(GO:0008494)
0.0	4.2	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.1	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.0	0.7	GO:0005521	lamin binding(GO:0005521)
0.0	1.8	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	1.1	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.2	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.0	0.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.9	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0	0.9	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	1.0	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.0	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	1.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.1	GO:0004488	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0	0.1	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.0	0.1	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.6	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.1	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.0	0.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.0	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	1.0	GO:0097110	scaffold protein binding(GO:0097110)
0.0	1.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	0.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.4	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.2	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.1	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0	0.8	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.0	0.3	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.1	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.0	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0	0.2	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0032356	oxidized DNA binding(GO:0032356)
0.0	0.2	GO:0015929	hexosaminidase activity(GO:0015929)
0.0	1.7	GO:0005539	glycosaminoglycan binding(GO:0005539)
0.0	0.2	GO:0031005	filamin binding(GO:0031005)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.4	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	1.1	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.0	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0	0.0	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.3	GO:0000146	microfilament motor activity(GO:0000146)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.0	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.1	3.3	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.0	4.0	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
1.0	3.0	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.9	3.4	GO:0007525	somatic muscle development(GO:0007525)
0.8	1.6	GO:0035995	detection of muscle stretch(GO:0035995)
0.5	1.6	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.5	1.5	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.5	1.4	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.5	1.4	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.4	32.6	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.4	5.9	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.4	1.7	GO:0002317	plasma cell differentiation(GO:0002317)
0.4	2.8	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.4	2.0	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.4	1.6	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.4	2.6	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.4	1.8	GO:0048539	bone marrow development(GO:0048539)
0.3	0.9	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.3	2.4	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3	1.2	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.3	2.8	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2	1.0	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.2	3.1	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2	1.0	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2	0.7	GO:1901899	positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2	3.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.2	1.7	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.2	0.6	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.2	1.0	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2	2.2	GO:0034465	response to carbon monoxide(GO:0034465)
0.2	0.8	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.2	0.6	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.2	0.8	GO:2001153	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2	3.5	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2	1.6	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	0.7	GO:1904616	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.2	1.9	GO:0006600	creatine metabolic process(GO:0006600)
0.2	1.6	GO:0048747	muscle fiber development(GO:0048747)
0.2	0.3	GO:0030500	regulation of bone mineralization(GO:0030500)
0.2	1.2	GO:0071694	sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.2	0.8	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	2.6	GO:0006527	arginine catabolic process(GO:0006527)
0.2	0.6	GO:0006051	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2	1.0	GO:0018095	protein polyglutamylation(GO:0018095)
0.2	0.5	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.1	3.1	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.7	GO:1990834	response to odorant(GO:1990834)
0.1	0.4	GO:1905154	negative regulation of membrane invagination(GO:1905154)
0.1	0.7	GO:0015862	uridine transport(GO:0015862)
0.1	0.4	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.1	0.4	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	2.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.5	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.1	1.5	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.4	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1	0.9	GO:1902302	regulation of potassium ion export(GO:1902302)
0.1	0.5	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1	0.4	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.2	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.4	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1	1.1	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.5	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1	0.7	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1	0.8	GO:0015793	glycerol transport(GO:0015793)
0.1	0.6	GO:0061738	late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.9	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.1	0.4	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	1.6	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.3	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	0.5	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1	0.5	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.1	0.6	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	2.3	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.1	0.9	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.3	GO:0014016	neuroblast differentiation(GO:0014016)
0.1	0.9	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1	0.6	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.1	0.8	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.4	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	0.3	GO:0006260	DNA replication(GO:0006260)
0.1	0.4	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	0.3	GO:0021558	trochlear nerve development(GO:0021558)
0.1	2.6	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.1	1.3	GO:0045475	locomotor rhythm(GO:0045475)
0.1	0.3	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.4	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	1.6	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.3	GO:0035854	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1	0.2	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1	0.4	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1	0.9	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.4	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1	0.9	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.4	GO:1905040	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1	0.8	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.3	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.1	0.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.2	GO:0032252	secretory granule localization(GO:0032252)
0.1	0.3	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.1	1.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.9	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	1.2	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.1	2.6	GO:0042572	retinol metabolic process(GO:0042572)
0.1	0.3	GO:0010193	response to ozone(GO:0010193)
0.1	0.7	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	0.1	GO:0002331	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.1	1.2	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.1	GO:0061461	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1	0.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.7	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	1.4	GO:0032060	bleb assembly(GO:0032060)
0.1	0.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.4	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.5	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.5	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.1	0.9	GO:0030239	myofibril assembly(GO:0030239)
0.1	0.1	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1	0.6	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.1	0.8	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	0.9	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.7	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.1	0.4	GO:0030421	defecation(GO:0030421)
0.1	0.1	GO:0061743	motor learning(GO:0061743)
0.1	0.4	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.1	0.2	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.2	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001) positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1	1.4	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.7	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.2	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.1	0.3	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1	0.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.1	0.2	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1	0.1	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.1	0.4	GO:0002326	B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.1	GO:0071313	cellular response to caffeine(GO:0071313)
0.1	0.6	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.1	0.2	GO:0060437	lung growth(GO:0060437)
0.1	0.3	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.1	0.2	GO:0070213	negative regulation of sister chromatid cohesion(GO:0045875) protein auto-ADP-ribosylation(GO:0070213)
0.1	0.3	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.2	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.2	GO:1901098	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.0	0.2	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0	0.7	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.2	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.5	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	1.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	1.4	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.2	GO:1903436	regulation of cytokinetic process(GO:0032954) positive regulation of centriole replication(GO:0046601) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0	1.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.0	0.6	GO:0080111	DNA demethylation(GO:0080111)
0.0	1.8	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	3.4	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.2	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0	0.0	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.1	GO:1903925	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	1.5	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.3	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.3	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.6	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	1.8	GO:0031529	ruffle organization(GO:0031529)
0.0	0.4	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	1.5	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.6	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	2.6	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	1.0	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.6	GO:0043586	tongue development(GO:0043586)
0.0	0.2	GO:1990262	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0	0.2	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.3	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0	0.5	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.2	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0	0.1	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.8	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.2	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.3	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:1904261	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.3	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.1	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.0	0.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.3	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0045820	negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0	0.5	GO:0010761	fibroblast migration(GO:0010761)
0.0	4.4	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	0.3	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	1.0	GO:0003012	muscle system process(GO:0003012)
0.0	1.5	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.6	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:1902723	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.2	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.1	GO:0061484	inner cell mass cell differentiation(GO:0001826) hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670) saliva secretion(GO:0046541)
0.0	0.5	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	1.5	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	0.7	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.3	GO:1903362	regulation of cellular protein catabolic process(GO:1903362)
0.0	0.4	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	0.4	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.5	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.4	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.3	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.2	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.4	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.3	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.1	GO:0061087	negative regulation of histone H3-K27 methylation(GO:0061086) positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.1	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0	0.1	GO:0001806	type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807)
0.0	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.4	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.3	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.0	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.8	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.6	GO:0006266	DNA ligation(GO:0006266)
0.0	0.1	GO:0071934	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0	0.2	GO:0051412	response to corticosterone(GO:0051412)
0.0	0.2	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.1	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.7	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	2.5	GO:0001764	neuron migration(GO:0001764)
0.0	0.3	GO:0009299	mRNA transcription(GO:0009299)
0.0	2.2	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	0.4	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.4	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	1.0	GO:1902400	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	1.3	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.4	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.3	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.3	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.3	GO:0045765	regulation of angiogenesis(GO:0045765)
0.0	0.5	GO:0048255	mRNA stabilization(GO:0048255)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.1	GO:0001824	blastocyst development(GO:0001824)
0.0	0.2	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0045444	fat cell differentiation(GO:0045444)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.5	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.3	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.3	GO:0009247	glycolipid biosynthetic process(GO:0009247)
0.0	0.1	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.7	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.9	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:2000501	regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.0	GO:0070671	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	1.5	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0043542	endothelial cell migration(GO:0043542)
0.0	0.0	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.5	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.8	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.6	8.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.6	0.6	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.5	13.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4	7.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4	6.7	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	14.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.3	1.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3	7.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	6.1	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.2	7.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	13.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.2	6.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	14.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	8.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	2.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	5.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	1.8	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	3.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	5.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	6.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	3.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	7.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.0	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.1	13.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	2.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	3.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.9	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.6	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	7.7	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	0.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	3.2	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	0.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	2.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	1.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.9	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	0.8	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.9	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	7.4	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	2.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	5.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	1.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	0.8	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	1.2	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	1.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	6.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	4.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	6.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.9	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.5	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	4.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.8	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	1.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME SIGNALLING BY NGF	Genes involved in Signalling by NGF
0.0	0.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.5	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	1.9	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	2.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	3.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	1.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	3.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.8	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.6	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	3.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.9	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.9	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	1.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	3.7	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.8	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	2.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.9	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.7	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME AMYLOIDS	Genes involved in Amyloids

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0000035	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.3	1.6	GO:0042289	MHC class II protein binding(GO:0042289)
0.3	0.9	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.2	1.4	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.2	0.5	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.2	0.5	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.1	0.6	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	1.7	GO:0043047	single-stranded telomeric DNA binding(GO:0043047)
0.1	0.3	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	1.4	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.5	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1	0.3	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1	1.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.6	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.5	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	4.5	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	1.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.7	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1	0.5	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	1.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.3	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	1.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.3	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.8	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.7	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	1.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.3	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.7	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.3	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.9	GO:0031489	myosin V binding(GO:0031489)
0.0	1.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.8	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.0	0.8	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.3	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0004819	glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0	0.3	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0	0.6	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.3	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	1.0	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.4	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.7	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.9	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.2	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0048156	tau protein binding(GO:0048156)
0.0	0.5	GO:0019894	kinesin binding(GO:0019894)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	26.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	2.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	4.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	0.7	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	3.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	3.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	3.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	2.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	1.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.8	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	7.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	2.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	2.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	1.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.5	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	1.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.7	PID TGFBR PATHWAY	TGF-beta receptor signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.8	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	1.0	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.1	1.3	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	0.5	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.3	GO:1903722	regulation of centriole elongation(GO:1903722)
0.1	0.1	GO:0035690	cellular response to drug(GO:0035690)
0.1	0.6	GO:0003360	brainstem development(GO:0003360)
0.1	0.1	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1	1.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.3	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.0	0.7	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.0	1.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.3	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.1	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.0	0.4	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.2	GO:0015722	canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.0	0.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.2	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.0	0.2	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.4	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.3	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.4	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.4	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.1	GO:2000332	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.2	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	3.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.9	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.6	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.6	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.5	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.7	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	1.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	1.0	PID AURORA B PATHWAY	Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	6.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	0.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	2.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	4.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.9	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	0.5	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.1	0.3	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.1	1.6	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.1	0.8	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	1.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	0.5	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0098770	FBXO family protein binding(GO:0098770)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.7	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6	3.3	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.3	1.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.2	1.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.2	2.3	GO:0032808	lacrimal gland development(GO:0032808)
0.2	0.6	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	0.6	GO:0061198	fungiform papilla formation(GO:0061198)
0.1	1.8	GO:0051639	actin filament network formation(GO:0051639)
0.1	1.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	5.1	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.1	0.3	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1	2.3	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.1	0.4	GO:0043988	histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.1	0.6	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1	0.2	GO:0072560	glandular epithelial cell maturation(GO:0002071) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.1	2.3	GO:0045730	respiratory burst(GO:0045730)
0.1	0.6	GO:0051552	flavone metabolic process(GO:0051552)
0.1	0.2	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0	1.5	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	0.2	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.5	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.2	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.0	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.4	GO:0046958	nonassociative learning(GO:0046958)
0.0	0.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.6	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.2	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.1	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
0.0	0.7	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.2	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0016333	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0	0.1	GO:0090212	vitamin E metabolic process(GO:0042360) regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0	2.3	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.2	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	2.3	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.2	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.1	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.3	GO:0006833	water transport(GO:0006833)
0.0	0.0	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.8	26.4	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
7.6	22.7	GO:0051097	negative regulation of helicase activity(GO:0051097)
7.5	59.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
7.0	20.9	GO:0045062	extrathymic T cell selection(GO:0045062)
6.9	34.6	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
6.4	25.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
6.1	18.2	GO:0006624	vacuolar protein processing(GO:0006624)
4.8	19.2	GO:0072308	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
4.6	50.6	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
3.1	12.5	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.8	11.3	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
2.7	29.5	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
2.6	13.1	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
2.5	12.5	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
2.4	12.1	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
2.4	9.4	GO:0046967	cytosol to ER transport(GO:0046967)
2.3	11.6	GO:0035549	positive regulation of interferon-beta secretion(GO:0035549)
2.3	6.9	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
2.1	17.0	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
2.1	6.2	GO:1990108	protein linear deubiquitination(GO:1990108)
2.0	13.8	GO:0018377	protein myristoylation(GO:0018377)
1.9	23.2	GO:0035457	cellular response to interferon-alpha(GO:0035457)
1.9	18.7	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.6	7.8	GO:0019805	quinolinate biosynthetic process(GO:0019805)
1.5	13.1	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
1.4	5.6	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.4	4.1	GO:1900368	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
1.3	3.8	GO:0007290	spermatid nucleus elongation(GO:0007290)
1.2	5.9	GO:0070842	aggresome assembly(GO:0070842)
1.2	1.2	GO:0002731	negative regulation of dendritic cell cytokine production(GO:0002731)
1.1	11.4	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
1.1	53.6	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
1.1	8.9	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.1	2.1	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
1.0	6.2	GO:0072007	mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
1.0	17.4	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
1.0	4.0	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.0	3.0	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
1.0	9.0	GO:0016553	base conversion or substitution editing(GO:0016553)
1.0	14.7	GO:0010623	programmed cell death involved in cell development(GO:0010623)
1.0	2.9	GO:1905246	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.0	1.0	GO:1905154	negative regulation of membrane invagination(GO:1905154)
0.8	3.9	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.8	5.4	GO:0033590	response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.7	1.5	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.7	1.4	GO:0006059	hexitol metabolic process(GO:0006059)
0.7	4.2	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.7	69.0	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.7	41.6	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.7	5.4	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.7	7.4	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.6	4.4	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.6	2.5	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6	1.9	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.6	4.6	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.6	4.6	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.6	3.9	GO:0098704	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.6	10.6	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.6	3.3	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.6	8.9	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.5	12.0	GO:0042100	B cell proliferation(GO:0042100)
0.5	58.7	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.5	2.1	GO:0080009	mRNA methylation(GO:0080009)
0.5	6.4	GO:0019388	galactose catabolic process(GO:0019388)
0.5	5.9	GO:1904896	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.5	2.7	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.4	8.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.4	4.6	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.4	1.2	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.4	1.2	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.4	2.8	GO:0045425	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.4	4.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4	1.1	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.4	2.5	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.4	3.5	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.3	1.3	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.3	2.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.3	1.3	GO:0007296	vitellogenesis(GO:0007296)
0.3	2.9	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3	1.6	GO:0016199	axon midline choice point recognition(GO:0016199) cellular response to norepinephrine stimulus(GO:0071874)
0.3	1.2	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.3	49.7	GO:0006906	vesicle fusion(GO:0006906)
0.3	0.9	GO:1990737	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.3	1.8	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.3	14.8	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.3	13.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.3	4.5	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.3	0.8	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
0.3	9.7	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.3	0.5	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.2	4.2	GO:0072643	interferon-gamma secretion(GO:0072643)
0.2	0.2	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2	5.6	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2	2.7	GO:0033227	dsRNA transport(GO:0033227)
0.2	0.9	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.2	6.5	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.2	0.7	GO:1990169	detoxification of copper ion(GO:0010273) elastin metabolic process(GO:0051541) cellular response to lead ion(GO:0071284) stress response to copper ion(GO:1990169)
0.2	1.5	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2	2.4	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.2	10.8	GO:0006298	mismatch repair(GO:0006298)
0.2	0.4	GO:0035787	cell migration involved in kidney development(GO:0035787) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.2	1.0	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2	1.9	GO:0001783	B cell apoptotic process(GO:0001783)
0.2	5.0	GO:0030890	positive regulation of B cell proliferation(GO:0030890)
0.2	3.0	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.2	0.5	GO:0055099	detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.2	2.6	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.2	1.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2	0.2	GO:0072179	nephric duct formation(GO:0072179)
0.2	1.3	GO:0031053	primary miRNA processing(GO:0031053)
0.2	4.9	GO:0035456	response to interferon-beta(GO:0035456)
0.2	1.6	GO:0010506	regulation of autophagy(GO:0010506)
0.2	0.5	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.2	0.3	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1	1.1	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1	0.4	GO:0045345	positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1	1.3	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	0.3	GO:0070987	error-free translesion synthesis(GO:0070987)
0.1	2.4	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1	0.7	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1	1.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	1.0	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.1	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1	0.8	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	1.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.2	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	1.3	GO:0006554	lysine catabolic process(GO:0006554)
0.1	3.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	1.2	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.1	2.0	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	0.5	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	2.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.6	GO:2001023	regulation of response to drug(GO:2001023)
0.1	0.2	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1	0.2	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1	3.4	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.1	0.3	GO:1903598	receptor-mediated virion attachment to host cell(GO:0046813) positive regulation of gap junction assembly(GO:1903598)
0.1	2.0	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.3	GO:1901339	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	1.5	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.5	GO:0070836	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1	0.5	GO:0032916	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1	0.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1	1.0	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.1	3.5	GO:0006536	glutamate metabolic process(GO:0006536)
0.1	25.5	GO:0009615	response to virus(GO:0009615)
0.1	1.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1	0.3	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	1.3	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.1	0.4	GO:0071494	cellular response to UV-C(GO:0071494)
0.1	1.9	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	1.2	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.3	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.1	0.2	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1	0.4	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.1	0.4	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1	0.7	GO:0015886	heme transport(GO:0015886)
0.1	1.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	1.1	GO:0003094	glomerular filtration(GO:0003094)
0.1	2.6	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.1	0.8	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	3.8	GO:0002456	T cell mediated immunity(GO:0002456)
0.1	0.8	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.1	0.5	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	0.7	GO:0043473	pigmentation(GO:0043473)
0.1	0.1	GO:0016048	detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.1	0.4	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.2	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.0	0.1	GO:0021779	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	1.9	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.3	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.2	GO:0071346	cellular response to interferon-gamma(GO:0071346)
0.0	1.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	2.7	GO:0042490	mechanoreceptor differentiation(GO:0042490) inner ear receptor cell differentiation(GO:0060113)
0.0	0.3	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.1	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0	2.0	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.4	GO:0051972	regulation of telomerase activity(GO:0051972)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.2	GO:0045137	development of primary sexual characteristics(GO:0045137)
0.0	0.1	GO:0070781	arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0	0.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.6	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.3	GO:0035307	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.2	GO:1902904	vacuolar transmembrane transport(GO:0034486) late endosomal microautophagy(GO:0061738) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0	2.4	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0	0.4	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.8	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.1	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	3.3	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.3	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	2.3	GO:0048477	oogenesis(GO:0048477)
0.0	2.9	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.1	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	3.1	GO:0051603	proteolysis involved in cellular protein catabolic process(GO:0051603)
0.0	0.2	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0	0.1	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.1	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.5	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.6	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	4.4	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.2	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	1.0	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0	0.4	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.3	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.7	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.1	GO:0044256	angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.1	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.2	GO:0048839	inner ear development(GO:0048839)
0.0	0.1	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.2	GO:0030091	protein repair(GO:0030091)
0.0	0.8	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.1	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	2.4	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	1.5	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.2	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.6	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	1.8	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.4	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.5	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.1	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0	0.2	GO:0060711	labyrinthine layer development(GO:0060711)
0.0	1.0	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0	0.2	GO:0006413	translational initiation(GO:0006413)
0.0	0.0	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
0.0	0.4	GO:0031055	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0	0.2	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.1	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	1.7	GO:0015992	proton transport(GO:0015992)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.4	6.6	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	12.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	1.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	6.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	6.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.2	4.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	10.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.1	4.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	4.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	2.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	4.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	2.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	3.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	1.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	0.9	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	3.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	1.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	5.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	1.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	4.7	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	2.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.4	5.9	GO:0005916	fascia adherens(GO:0005916)
0.4	1.4	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3	3.8	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.2	2.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	0.5	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	1.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.2	5.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.2	1.0	GO:1990357	terminal web(GO:1990357)
0.2	0.9	GO:1902560	GMP reductase complex(GO:1902560)
0.1	0.9	GO:0043196	varicosity(GO:0043196)
0.1	0.8	GO:0071203	WASH complex(GO:0071203)
0.1	1.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	2.0	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	1.7	GO:0032433	filopodium tip(GO:0032433)
0.1	1.1	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.1	1.3	GO:0005922	connexon complex(GO:0005922)
0.1	0.5	GO:0036021	endolysosome lumen(GO:0036021)
0.1	1.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.6	GO:0045179	apical cortex(GO:0045179)
0.1	2.6	GO:0000421	autophagosome membrane(GO:0000421)
0.1	0.5	GO:0035976	AP1 complex(GO:0035976)
0.1	7.6	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	0.3	GO:0031501	mannosyltransferase complex(GO:0031501)
0.1	0.5	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.1	0.6	GO:0072687	meiotic spindle(GO:0072687)
0.1	0.8	GO:0031209	SCAR complex(GO:0031209)
0.1	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	1.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.7	GO:0030478	actin cap(GO:0030478)
0.0	0.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.3	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.2	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.2	GO:0042643	actomyosin, actin portion(GO:0042643)
0.0	0.2	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	0.2	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.6	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.4	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	1.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	1.7	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	7.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	2.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.6	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	1.8	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	3.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	1.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.8	GO:0001533	cornified envelope(GO:0001533)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	2.4	GO:0030018	Z disc(GO:0030018)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.6	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	8.9	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2	2.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2	2.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	4.1	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	2.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	2.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	1.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.3	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	4.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	3.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	1.0	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	2.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	1.4	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	2.0	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	1.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.0	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.0	2.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	2.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.9	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.8	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	1.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.7	GO:0016403	dimethylargininase activity(GO:0016403)
0.3	1.3	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2	0.5	GO:0016842	amidine-lyase activity(GO:0016842)
0.2	0.6	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2	0.6	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.2	1.3	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.2	0.5	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2	0.5	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.2	0.5	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1	0.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.1	0.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	1.3	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.2	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.2	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.1	1.0	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	0.6	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.3	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1	0.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	0.9	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.3	GO:0039552	RIG-I binding(GO:0039552)
0.1	0.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	1.7	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.7	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.3	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0	1.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.0	0.3	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.3	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.9	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.9	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0	0.2	GO:0003916	DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0	0.3	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.2	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.3	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0	0.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.3	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	1.5	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	1.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	1.6	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	1.5	GO:0016209	antioxidant activity(GO:0016209)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.0	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.0	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.7	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.2	0.9	GO:0008940	nitrate reductase activity(GO:0008940)
0.2	2.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.2	0.5	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1	0.3	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	4.3	GO:0019843	rRNA binding(GO:0019843)
0.1	0.8	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0004769	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.0	0.3	GO:0071253	connexin binding(GO:0071253)
0.0	0.3	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.1	GO:0042019	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0	0.4	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.4	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0047708	biotinidase activity(GO:0047708)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	2.1	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	5.5	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	12.3	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	2.6	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	0.6	GO:0099512	supramolecular fiber(GO:0099512)
0.2	0.8	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.2	3.1	GO:0097512	cardiac myofibril(GO:0097512)
0.2	0.8	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	2.2	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.2	0.8	GO:0042643	actomyosin, actin portion(GO:0042643)
0.2	1.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.9	GO:0005927	muscle tendon junction(GO:0005927)
0.1	0.8	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1	0.4	GO:0005715	late recombination nodule(GO:0005715)
0.1	0.4	GO:0018444	translation release factor complex(GO:0018444)
0.1	0.3	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	4.6	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.5	GO:0031673	H zone(GO:0031673)
0.1	1.0	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.7	GO:0032584	growth cone membrane(GO:0032584)
0.1	0.7	GO:0019815	B cell receptor complex(GO:0019815)
0.1	2.4	GO:0071564	npBAF complex(GO:0071564)
0.1	0.7	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.1	0.6	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.1	0.8	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.4	GO:1990075	periciliary membrane compartment(GO:1990075)
0.1	0.3	GO:0060187	cell pole(GO:0060187)
0.1	0.1	GO:0019034	viral replication complex(GO:0019034)
0.1	0.1	GO:0005712	chiasma(GO:0005712)
0.1	1.6	GO:0005861	troponin complex(GO:0005861)
0.1	0.7	GO:0032010	phagolysosome(GO:0032010)
0.1	0.2	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	1.5	GO:0097342	ripoptosome(GO:0097342)
0.1	1.6	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.4	GO:0031674	I band(GO:0031674)
0.1	0.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.2	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	0.4	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	1.0	GO:0008091	spectrin(GO:0008091)
0.1	1.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.3	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	1.5	GO:0000242	pericentriolar material(GO:0000242)
0.1	1.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.1	GO:0031513	photoreceptor outer segment(GO:0001750) nonmotile primary cilium(GO:0031513) primary cilium(GO:0072372)
0.1	0.3	GO:0036398	TCR signalosome(GO:0036398)
0.1	0.6	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.3	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.3	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	0.1	GO:0034680	integrin alpha10-beta1 complex(GO:0034680)
0.1	1.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	0.2	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.1	0.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.2	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1	0.2	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	1.6	GO:0031143	pseudopodium(GO:0031143)
0.1	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.3	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	0.4	GO:0071953	elastic fiber(GO:0071953)
0.1	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.2	GO:1990246	uniplex complex(GO:1990246)
0.1	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.5	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0030430	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0	0.4	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	1.1	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.6	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.0	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	0.8	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.8	GO:0034709	methylosome(GO:0034709)
0.0	0.2	GO:0036379	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0	0.2	GO:0001652	granular component(GO:0001652)
0.0	0.4	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.2	GO:0033263	CORVET complex(GO:0033263)
0.0	0.3	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.4	GO:0097255	R2TP complex(GO:0097255)
0.0	0.1	GO:0031905	early endosome lumen(GO:0031905)
0.0	0.1	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	0.4	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	1.4	GO:0042629	mast cell granule(GO:0042629)
0.0	0.8	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	0.2	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.5	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.2	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0	0.7	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	3.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.2	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.4	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.3	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	0.2	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
0.0	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:1990015	mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0	0.8	GO:0035861	site of double-strand break(GO:0035861)
0.0	1.5	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0045177	apical part of cell(GO:0045177)
0.0	0.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.2	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.1	GO:0030905	retromer, tubulation complex(GO:0030905)
0.0	0.3	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.0	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.0	0.1	GO:0036128	CatSper complex(GO:0036128)
0.0	0.8	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.6	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.2	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.7	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.0	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0090568	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.3	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.2	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.3	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.1	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0033010	paranodal junction(GO:0033010)
0.0	0.0	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	0.0	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.9	GO:0031672	A band(GO:0031672)
0.0	0.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.3	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	1.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.6	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.4	GO:0031105	septin complex(GO:0031105)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0097422	tubular endosome(GO:0097422)
0.0	0.0	GO:0005713	recombination nodule(GO:0005713)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	1.4	GO:0015030	Cajal body(GO:0015030)
0.0	0.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.5	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0005873	plus-end kinesin complex(GO:0005873)
0.0	0.6	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0070195	growth hormone receptor complex(GO:0070195)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0033643	host cell part(GO:0033643)
0.0	0.0	GO:0044449	contractile fiber part(GO:0044449)
0.0	0.4	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0048500	signal recognition particle(GO:0048500)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.0	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.6	GO:0001772	immunological synapse(GO:0001772)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:1990393	3M complex(GO:1990393)
0.0	0.0	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.0	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.3	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.0	0.2	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	5.1	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.0	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	1.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.0	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0	0.0	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.2	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	0.4	GO:0016235	aggresome(GO:0016235)
0.0	3.1	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.4	GO:0031594	neuromuscular junction(GO:0031594)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	0.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	2.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	1.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	7.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	8.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	2.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	5.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	2.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	4.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	2.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	3.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	1.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	2.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	2.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.7	GO:0097179	protease inhibitor complex(GO:0097179)
0.3	1.1	GO:1990423	RZZ complex(GO:1990423)
0.3	3.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.2	0.9	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.1	0.6	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	0.7	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	1.8	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.1	1.1	GO:0005922	connexon complex(GO:0005922)
0.1	0.2	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.0	0.4	GO:0033391	chromatoid body(GO:0033391)
0.0	2.1	GO:0005871	kinesin complex(GO:0005871)
0.0	0.3	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.6	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.5	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	2.3	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0042643	actomyosin, actin portion(GO:0042643)
0.0	2.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.6	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.3	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.0	5.6	GO:0016607	nuclear speck(GO:0016607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	6.3	GO:0005610	laminin-5 complex(GO:0005610)
0.7	3.4	GO:0097179	protease inhibitor complex(GO:0097179)
0.6	6.5	GO:0097413	Lewy body(GO:0097413)
0.6	9.6	GO:0005922	connexon complex(GO:0005922)
0.5	2.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.4	1.1	GO:1902636	kinociliary basal body(GO:1902636)
0.3	12.7	GO:0045095	keratin filament(GO:0045095)
0.2	3.3	GO:0030478	actin cap(GO:0030478)
0.2	0.7	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	4.1	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	0.4	GO:0031523	Myb complex(GO:0031523)
0.1	0.5	GO:0035838	growing cell tip(GO:0035838)
0.1	1.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.3	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	5.7	GO:0001533	cornified envelope(GO:0001533)
0.1	0.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	1.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	8.0	GO:0045178	basal part of cell(GO:0045178)
0.1	0.9	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1	0.8	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	1.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.6	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	0.8	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.7	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.0	2.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	2.7	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	1.3	GO:0036379	myofilament(GO:0036379)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.4	GO:0033270	voltage-gated sodium channel complex(GO:0001518) paranode region of axon(GO:0033270)
0.0	2.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	8.1	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	1.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.1	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	4.6	GO:0016324	apical plasma membrane(GO:0016324)
0.0	8.6	GO:0005925	focal adhesion(GO:0005925)
0.0	0.3	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.1	0.3	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.1	0.8	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.8	GO:0000050	urea cycle(GO:0000050)
0.0	1.6	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.1	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.0	0.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0051462	cortisol secretion(GO:0043400) positive regulation of corticotropin secretion(GO:0051461) regulation of cortisol secretion(GO:0051462) negative regulation of glucagon secretion(GO:0070093) cellular response to cocaine(GO:0071314) positive regulation of corticosterone secretion(GO:2000854)
0.0	0.1	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0	0.1	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	0.5	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.7	GO:0007567	parturition(GO:0007567)
0.0	0.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.5	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0	2.7	GO:0021987	cerebral cortex development(GO:0021987)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.5	GO:0097352	autophagosome maturation(GO:0097352)
0.0	0.4	GO:0002076	osteoblast development(GO:0002076)
0.0	0.3	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.9	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	2.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	3.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.7	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	3.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.8	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	1.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	1.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	2.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	0.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	2.0	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.6	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	3.0	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	1.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.9	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.2	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	2.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.9	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	1.7	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	1.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	3.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.6	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.7	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.1	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.7	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	4.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	0.9	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	4.2	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	1.1	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	2.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.3	6.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	3.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2	3.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	5.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	4.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	3.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	13.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	3.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	2.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	1.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	3.3	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.8	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	2.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	10.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	4.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	1.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	1.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	1.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	4.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.0	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.9	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	2.4	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.8	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	1.6	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.5	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.6	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	0.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.3	11.5	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.3	6.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	1.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	16.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	12.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	2.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	2.5	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.2	4.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	10.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	3.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	1.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	1.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	5.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	3.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	1.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	1.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	2.4	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	4.8	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.7	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	2.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	2.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	4.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	0.2	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.1	0.8	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	2.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.7	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	2.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	0.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	0.8	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	2.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	4.0	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.1	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	0.4	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	1.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	1.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	0.6	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.1	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.4	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.1	0.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	2.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.2	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	1.2	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.1	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	1.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	0.5	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.6	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	0.9	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	3.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	6.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	1.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	1.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	2.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	1.8	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.9	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	1.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	2.8	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.1	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.9	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	1.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	2.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	3.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.8	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.8	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.5	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.2	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.5	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.1	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.0	0.1	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.1	21.2	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
6.6	19.9	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
5.9	35.4	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
5.4	21.6	GO:1902612	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
4.7	14.0	GO:0032773	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
3.1	12.5	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
3.0	8.9	GO:0048627	myoblast development(GO:0048627)
2.9	8.8	GO:0060166	olfactory pit development(GO:0060166)
2.8	11.2	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
2.8	25.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
2.6	10.6	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
2.5	19.8	GO:0031642	negative regulation of myelination(GO:0031642)
2.4	19.2	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
2.4	7.2	GO:1990764	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
2.3	67.3	GO:0031581	hemidesmosome assembly(GO:0031581)
2.3	6.8	GO:0019858	cytosine metabolic process(GO:0019858)
2.2	6.5	GO:0002588	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
2.1	8.3	GO:0046108	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
2.0	13.9	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
2.0	7.9	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
1.9	5.8	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.9	1.9	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
1.9	5.7	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.9	1.9	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
1.9	9.5	GO:0097102	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
1.9	9.5	GO:1903284	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.8	9.2	GO:0002159	desmosome assembly(GO:0002159)
1.8	12.8	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
1.8	9.0	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
1.8	1.8	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
1.7	8.7	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
1.7	5.2	GO:0046066	dGDP metabolic process(GO:0046066)
1.7	6.9	GO:0046086	adenosine biosynthetic process(GO:0046086)
1.7	11.9	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
1.7	1.7	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
1.7	5.0	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
1.7	11.7	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
1.7	8.3	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
1.7	18.2	GO:0009414	response to water deprivation(GO:0009414)
1.6	4.9	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.6	1.6	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
1.6	4.9	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.6	9.7	GO:0006789	bilirubin conjugation(GO:0006789)
1.6	1.6	GO:0048817	negative regulation of hair follicle maturation(GO:0048817)
1.6	17.7	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
1.6	6.4	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
1.6	6.4	GO:0003409	optic cup structural organization(GO:0003409)
1.6	6.3	GO:0033484	nitric oxide homeostasis(GO:0033484)
1.6	7.8	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.5	6.2	GO:0071461	cellular response to redox state(GO:0071461)
1.5	1.5	GO:0061441	renal artery morphogenesis(GO:0061441)
1.5	4.6	GO:0006738	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
1.5	4.6	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.5	3.0	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.5	6.0	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
1.5	3.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
1.5	1.5	GO:0009996	negative regulation of cell fate specification(GO:0009996)
1.5	3.0	GO:2000683	regulation of cellular response to X-ray(GO:2000683)
1.5	4.4	GO:0035329	hippo signaling(GO:0035329)
1.5	4.4	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.5	8.8	GO:0002934	desmosome organization(GO:0002934)
1.4	17.2	GO:0001778	plasma membrane repair(GO:0001778)
1.4	4.3	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
1.4	12.8	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
1.4	4.2	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
1.4	15.5	GO:0099639	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
1.4	1.4	GO:0072023	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
1.4	11.2	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
1.4	1.4	GO:1900274	positive regulation of phospholipase C activity(GO:0010863) regulation of phospholipase C activity(GO:1900274)
1.4	2.8	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.4	6.9	GO:0030047	actin modification(GO:0030047)
1.4	6.8	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.4	5.4	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
1.4	4.1	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
1.3	9.4	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
1.3	2.7	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309)
1.3	4.0	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.3	3.9	GO:2000645	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of receptor catabolic process(GO:2000645)
1.3	11.8	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
1.3	2.6	GO:0060066	oviduct development(GO:0060066)
1.3	32.0	GO:0071294	cellular response to zinc ion(GO:0071294)
1.2	3.7	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
1.2	6.2	GO:1904579	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
1.2	5.0	GO:1900533	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
1.2	4.8	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
1.2	7.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
1.2	4.8	GO:0035900	response to isolation stress(GO:0035900)
1.2	3.6	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.2	7.1	GO:0072719	cellular response to cisplatin(GO:0072719)
1.2	5.9	GO:0097527	necroptotic signaling pathway(GO:0097527)
1.2	4.6	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
1.1	4.5	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.1	7.9	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
1.1	13.5	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
1.1	3.3	GO:0033341	regulation of collagen binding(GO:0033341)
1.1	4.4	GO:0042335	cuticle development(GO:0042335)
1.1	3.2	GO:1903722	regulation of centriole elongation(GO:1903722)
1.1	4.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
1.1	1.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
1.1	4.2	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0	3.1	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.0	2.0	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.0	3.1	GO:0006550	isoleucine catabolic process(GO:0006550)
1.0	11.2	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
1.0	4.1	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.0	5.1	GO:0007386	compartment pattern specification(GO:0007386)
1.0	8.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
1.0	3.0	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
1.0	8.0	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.0	5.0	GO:1990834	response to odorant(GO:1990834)
1.0	2.0	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
1.0	1.0	GO:0045976	negative regulation of mitotic cell cycle, embryonic(GO:0045976)
1.0	5.9	GO:0048549	positive regulation of pinocytosis(GO:0048549)
1.0	12.8	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
1.0	3.0	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
1.0	3.9	GO:0046952	ketone body catabolic process(GO:0046952)
1.0	2.9	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
1.0	2.9	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.0	3.9	GO:1902903	regulation of fibril organization(GO:1902903)
1.0	1.9	GO:2000374	regulation of oxygen metabolic process(GO:2000374)
1.0	5.8	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
1.0	2.9	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.0	3.8	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.9	3.8	GO:0044837	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.9	2.8	GO:0032289	central nervous system myelin formation(GO:0032289)
0.9	2.8	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.9	18.6	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.9	14.0	GO:0090168	Golgi reassembly(GO:0090168)
0.9	4.6	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.9	2.8	GO:0007412	axon target recognition(GO:0007412)
0.9	3.6	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.9	0.9	GO:0031017	exocrine pancreas development(GO:0031017)
0.9	0.9	GO:0072709	cellular response to sorbitol(GO:0072709)
0.9	7.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.9	2.7	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.9	2.7	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.9	3.5	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.9	3.5	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.9	6.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.9	0.9	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.9	3.4	GO:0046836	glycolipid transport(GO:0046836)
0.9	3.4	GO:0046110	xanthine metabolic process(GO:0046110)
0.9	0.9	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.9	10.3	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.9	3.4	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.9	7.7	GO:0015705	iodide transport(GO:0015705)
0.8	3.4	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.8	0.8	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
0.8	5.0	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.8	6.7	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.8	0.8	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.8	3.3	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.8	2.5	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.8	10.7	GO:0006089	lactate metabolic process(GO:0006089)
0.8	0.8	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.8	3.2	GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.8	1.6	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.8	5.6	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.8	1.6	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.8	2.4	GO:2000521	negative regulation of immunological synapse formation(GO:2000521)
0.8	1.6	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.8	6.3	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.8	5.5	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.8	12.5	GO:0016540	protein autoprocessing(GO:0016540)
0.8	3.1	GO:1904199	positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.8	3.9	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.8	7.0	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.8	0.8	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.8	6.2	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.8	5.4	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.8	5.4	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.8	0.8	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.7	2.2	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.7	2.2	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
0.7	5.2	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7	2.2	GO:0051414	response to cortisol(GO:0051414)
0.7	1.5	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.7	5.9	GO:0060056	mammary gland involution(GO:0060056)
0.7	5.1	GO:1903232	melanosome assembly(GO:1903232)
0.7	4.3	GO:0015820	leucine transport(GO:0015820)
0.7	2.1	GO:0019417	sulfur oxidation(GO:0019417)
0.7	1.4	GO:0010652	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.7	4.3	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.7	0.7	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.7	1.4	GO:0035567	non-canonical Wnt signaling pathway(GO:0035567) Wnt signaling pathway, planar cell polarity pathway(GO:0060071)
0.7	2.1	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.7	3.5	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.7	2.8	GO:0060594	mammary gland specification(GO:0060594)
0.7	1.4	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.7	2.1	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.7	2.1	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.7	0.7	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.7	9.6	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.7	3.4	GO:0035617	stress granule disassembly(GO:0035617)
0.7	0.7	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.7	3.4	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.7	1.4	GO:0002188	translation reinitiation(GO:0002188)
0.7	0.7	GO:0043457	regulation of cellular respiration(GO:0043457)
0.7	8.1	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.7	3.3	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.7	7.3	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.7	1.3	GO:0006788	heme oxidation(GO:0006788)
0.7	2.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.7	3.3	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.7	3.9	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.7	3.3	GO:0035063	nuclear speck organization(GO:0035063)
0.7	2.0	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.6	6.5	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.6	2.6	GO:2001151	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.6	1.3	GO:0007113	endomitotic cell cycle(GO:0007113)
0.6	2.6	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.6	1.9	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.6	3.8	GO:1903960	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.6	1.9	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.6	3.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.6	3.1	GO:0055064	chloride ion homeostasis(GO:0055064)
0.6	3.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.6	3.1	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.6	6.9	GO:0030043	actin filament fragmentation(GO:0030043)
0.6	2.5	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.6	0.6	GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.6	3.7	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.6	1.2	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.6	0.6	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.6	1.2	GO:0043132	NAD transport(GO:0043132)
0.6	1.8	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.6	33.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.6	0.6	GO:0010561	negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.6	8.9	GO:0032060	bleb assembly(GO:0032060)
0.6	5.9	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.6	2.9	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.6	1.2	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.6	1.8	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.6	1.7	GO:2000282	regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.6	0.6	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.6	2.3	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.6	3.4	GO:0015866	ADP transport(GO:0015866) ATP transport(GO:0015867) adenine nucleotide transport(GO:0051503)
0.6	2.3	GO:0051013	microtubule severing(GO:0051013)
0.6	2.8	GO:0098502	DNA dephosphorylation(GO:0098502)
0.6	6.2	GO:0034465	response to carbon monoxide(GO:0034465)
0.6	2.3	GO:0038089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.6	1.7	GO:0071030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.6	1.7	GO:0046521	sphingoid catabolic process(GO:0046521)
0.6	3.9	GO:0070294	renal sodium ion absorption(GO:0070294)
0.6	1.7	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.6	0.6	GO:0006106	fumarate metabolic process(GO:0006106)
0.6	0.6	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.6	2.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.6	0.6	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.5	1.6	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.5	1.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.5	1.1	GO:0035712	T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.5	2.7	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.5	3.2	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.5	2.2	GO:0006051	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.5	0.5	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.5	2.7	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.5	4.8	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.5	5.3	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.5	1.1	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.5	3.2	GO:0035803	egg coat formation(GO:0035803)
0.5	10.0	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.5	0.5	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.5	1.0	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.5	50.3	GO:0070268	cornification(GO:0070268)
0.5	2.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.5	1.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.5	2.1	GO:0018032	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.5	3.1	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.5	2.1	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.5	2.6	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.5	1.5	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.5	0.5	GO:0007041	lysosomal transport(GO:0007041)
0.5	1.0	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.5	1.5	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.5	2.6	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.5	6.6	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.5	0.5	GO:0072683	T cell extravasation(GO:0072683)
0.5	1.5	GO:0071790	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.5	0.5	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.5	1.5	GO:0071344	diphosphate metabolic process(GO:0071344)
0.5	1.5	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.5	3.0	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.5	9.0	GO:0044030	regulation of DNA methylation(GO:0044030)
0.5	0.5	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.5	3.0	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.5	1.5	GO:0031938	regulation of chromatin silencing at telomere(GO:0031938)
0.5	2.5	GO:1903243	negative regulation of cardiac muscle adaptation(GO:0010616) transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.5	0.5	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.5	3.4	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.5	2.0	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5	3.4	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5	1.5	GO:0071109	superior temporal gyrus development(GO:0071109)
0.5	1.9	GO:0033278	cell proliferation in midbrain(GO:0033278)
0.5	1.5	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.5	7.2	GO:0009629	response to gravity(GO:0009629)
0.5	2.4	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.5	0.5	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
0.5	1.9	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.5	1.4	GO:0015800	acidic amino acid transport(GO:0015800)
0.5	1.0	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.5	1.0	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.5	1.0	GO:0043311	regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.5	1.4	GO:0060151	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.5	3.3	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.5	7.1	GO:0008105	asymmetric protein localization(GO:0008105)
0.5	1.4	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.5	0.5	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.5	2.4	GO:0098706	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5	0.5	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.5	3.8	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.5	0.5	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.5	0.9	GO:0051036	regulation of endosome size(GO:0051036)
0.5	8.4	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.5	0.9	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.5	2.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5	2.8	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.5	1.4	GO:0060174	limb bud formation(GO:0060174)
0.5	0.9	GO:0019322	pentose biosynthetic process(GO:0019322)
0.5	0.9	GO:0006294	nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.5	0.5	GO:1903056	regulation of melanosome organization(GO:1903056)
0.5	8.6	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.5	1.4	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.5	3.6	GO:0045345	positive regulation of MHC class I biosynthetic process(GO:0045345)
0.5	0.5	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.4	1.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.4	1.3	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.4	4.9	GO:0043248	proteasome assembly(GO:0043248)
0.4	0.4	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.4	3.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.4	1.8	GO:0048145	regulation of fibroblast proliferation(GO:0048145)
0.4	0.9	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.4	1.8	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.4	1.8	GO:0001927	exocyst assembly(GO:0001927)
0.4	3.1	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.4	0.9	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.4	0.4	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.4	8.8	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.4	0.9	GO:0015853	adenine transport(GO:0015853)
0.4	2.2	GO:0001842	neural fold formation(GO:0001842)
0.4	2.2	GO:0002084	protein depalmitoylation(GO:0002084)
0.4	8.7	GO:0003334	keratinocyte development(GO:0003334)
0.4	2.6	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.4	2.2	GO:0034036	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4	1.7	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.4	0.4	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.4	0.4	GO:0070101	positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.4	6.0	GO:0051639	actin filament network formation(GO:0051639)
0.4	1.3	GO:1903674	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.4	2.6	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.4	4.7	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.4	3.9	GO:0036010	protein localization to endosome(GO:0036010)
0.4	1.3	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.4	1.3	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.4	1.7	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.4	1.3	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.4	0.4	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.4	1.3	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4	0.8	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.4	1.7	GO:0002880	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.4	3.3	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.4	3.3	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.4	2.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.4	3.3	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.4	0.4	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.4	2.0	GO:0071763	nuclear membrane organization(GO:0071763)
0.4	0.4	GO:0097694	establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.4	0.4	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.4	0.8	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.4	1.6	GO:0051187	cofactor catabolic process(GO:0051187)
0.4	0.4	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.4	1.6	GO:0072136	kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136)
0.4	0.8	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.4	0.4	GO:0003404	optic vesicle morphogenesis(GO:0003404)
0.4	1.6	GO:0046502	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.4	1.6	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.4	0.4	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451)
0.4	0.4	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.4	0.4	GO:1905064	negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.4	1.2	GO:0006597	spermine biosynthetic process(GO:0006597)
0.4	0.8	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.4	0.4	GO:0006114	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.4	2.3	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.4	6.6	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.4	2.7	GO:0032808	lacrimal gland development(GO:0032808)
0.4	3.1	GO:0034214	protein hexamerization(GO:0034214)
0.4	1.2	GO:1905224	clathrin-coated pit assembly(GO:1905224)
0.4	0.8	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.4	3.9	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.4	4.2	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.4	1.9	GO:0044351	macropinocytosis(GO:0044351)
0.4	1.5	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.4	0.4	GO:1903566	regulation of protein localization to cilium(GO:1903564) positive regulation of protein localization to cilium(GO:1903566)
0.4	0.8	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.4	1.1	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.4	9.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.4	1.5	GO:0046967	cytosol to ER transport(GO:0046967)
0.4	0.8	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.4	1.1	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4	0.4	GO:0032096	negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.4	2.3	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4	0.4	GO:0015917	aminophospholipid transport(GO:0015917)
0.4	1.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.4	0.7	GO:1990164	histone H2A phosphorylation(GO:1990164)
0.4	1.1	GO:2001169	regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171)
0.4	0.4	GO:0000103	sulfate assimilation(GO:0000103)
0.4	0.7	GO:0060437	lung growth(GO:0060437)
0.4	3.7	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4	0.4	GO:0003250	cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.4	0.7	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.4	0.4	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.4	0.7	GO:0097212	lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
0.4	0.4	GO:0060769	positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.4	1.5	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.4	0.7	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.4	0.7	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.4	3.7	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.4	2.6	GO:1900084	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084)
0.4	2.2	GO:1904925	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.4	1.1	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.4	1.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.4	10.2	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.4	1.5	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.4	2.6	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4	2.2	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4	1.4	GO:0044375	regulation of peroxisome size(GO:0044375)
0.4	2.2	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.4	0.4	GO:1902583	multi-organism intracellular transport(GO:1902583)
0.4	1.1	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.4	0.4	GO:0014002	astrocyte development(GO:0014002)
0.4	2.1	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.4	0.4	GO:1900223	positive regulation of beta-amyloid clearance(GO:1900223)
0.4	1.1	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.4	0.7	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4	0.4	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.4	1.4	GO:0031291	Ran protein signal transduction(GO:0031291)
0.4	1.1	GO:1904799	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.4	1.4	GO:0072658	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4	0.7	GO:0003149	membranous septum morphogenesis(GO:0003149)
0.4	1.1	GO:0052027	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.4	1.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.4	2.8	GO:0046847	filopodium assembly(GO:0046847)
0.4	14.7	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.4	2.8	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.3	9.1	GO:0032456	endocytic recycling(GO:0032456)
0.3	2.8	GO:0035733	hepatic stellate cell activation(GO:0035733)
0.3	2.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.3	0.7	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418)
0.3	0.7	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.3	1.4	GO:0075044	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.3	2.8	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.3	0.7	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.3	1.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3	1.4	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.3	2.4	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3	0.7	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.3	0.3	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.3	1.7	GO:2001076	regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.3	1.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3	0.3	GO:1902473	regulation of protein localization to synapse(GO:1902473)
0.3	0.3	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.3	1.3	GO:0015793	glycerol transport(GO:0015793)
0.3	0.7	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3	5.0	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.3	1.0	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.3	5.3	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.3	3.0	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.3	0.7	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.3	0.3	GO:0060074	synapse maturation(GO:0060074)
0.3	1.0	GO:1901571	icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.3	0.7	GO:0070933	histone H4 deacetylation(GO:0070933)
0.3	1.3	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.3	1.0	GO:0070370	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.3	1.0	GO:0090487	toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.3	1.3	GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.3	1.0	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.3	11.4	GO:1904031	positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.3	0.3	GO:2001020	regulation of response to DNA damage stimulus(GO:2001020)
0.3	0.6	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.3	0.3	GO:0030316	osteoclast differentiation(GO:0030316)
0.3	1.0	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3	20.3	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.3	0.3	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.3	1.3	GO:0035634	response to stilbenoid(GO:0035634)
0.3	2.2	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.3	1.0	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.3	1.6	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.3	0.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3	0.9	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.3	0.9	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3	0.9	GO:0042700	luteinizing hormone signaling pathway(GO:0042700)
0.3	0.6	GO:0018065	protein-cofactor linkage(GO:0018065)
0.3	1.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.3	0.9	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.3	1.9	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.3	1.9	GO:0021603	cranial nerve formation(GO:0021603)
0.3	0.6	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.3	3.1	GO:0010265	SCF complex assembly(GO:0010265)
0.3	2.2	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.3	1.9	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.3	0.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.3	0.3	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.3	2.8	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.3	0.9	GO:0051493	regulation of cytoskeleton organization(GO:0051493)
0.3	0.9	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.3	1.5	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.3	1.2	GO:0042256	mature ribosome assembly(GO:0042256)
0.3	1.2	GO:2000035	regulation of stem cell division(GO:2000035)
0.3	1.2	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3	0.3	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
0.3	1.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3	1.5	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.3	0.6	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.3	5.7	GO:0031529	ruffle organization(GO:0031529)
0.3	1.2	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.3	0.6	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.3	7.5	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.3	0.9	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
0.3	1.5	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.3	0.9	GO:0046061	dATP catabolic process(GO:0046061)
0.3	0.3	GO:0051784	negative regulation of nuclear division(GO:0051784)
0.3	0.9	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.3	1.8	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.3	0.9	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.3	0.3	GO:0043407	negative regulation of MAP kinase activity(GO:0043407)
0.3	0.9	GO:0000729	DNA double-strand break processing(GO:0000729)
0.3	0.6	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.3	1.8	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.3	6.4	GO:0043616	keratinocyte proliferation(GO:0043616)
0.3	0.6	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.3	12.0	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.3	1.5	GO:0015862	uridine transport(GO:0015862)
0.3	1.8	GO:1903921	protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.3	0.3	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.3	0.9	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3	2.3	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3	0.6	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.3	0.9	GO:0018377	protein myristoylation(GO:0018377)
0.3	0.3	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.3	0.9	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
0.3	0.9	GO:0006102	isocitrate metabolic process(GO:0006102)
0.3	1.2	GO:0061053	somite development(GO:0061053)
0.3	1.2	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3	0.9	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3	1.4	GO:0090161	Golgi ribbon formation(GO:0090161)
0.3	3.7	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.3	2.9	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3	3.7	GO:0031268	pseudopodium organization(GO:0031268)
0.3	1.4	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.3	0.9	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
0.3	1.1	GO:0003157	endocardium development(GO:0003157)
0.3	0.9	GO:1903028	positive regulation of opsonization(GO:1903028)
0.3	0.3	GO:0086091	regulation of heart rate by cardiac conduction(GO:0086091)
0.3	2.0	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3	1.1	GO:0006196	AMP catabolic process(GO:0006196)
0.3	0.8	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.3	1.7	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.3	2.5	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.3	0.6	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.3	1.1	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.3	0.3	GO:0032055	negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.3	3.9	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.3	7.2	GO:0009235	cobalamin metabolic process(GO:0009235)
0.3	0.8	GO:0021569	rhombomere 3 development(GO:0021569)
0.3	1.9	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.3	1.7	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3	1.4	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.3	1.1	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.3	0.6	GO:0001806	type IV hypersensitivity(GO:0001806)
0.3	2.8	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.3	0.3	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.3	1.6	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3	1.9	GO:0050863	regulation of T cell activation(GO:0050863)
0.3	0.8	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.3	0.5	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
0.3	1.1	GO:0035026	leading edge cell differentiation(GO:0035026)
0.3	0.5	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.3	0.5	GO:1901656	glycoside transport(GO:1901656)
0.3	0.5	GO:0042761	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.3	0.5	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.3	0.3	GO:0010634	positive regulation of epithelial cell migration(GO:0010634)
0.3	1.1	GO:0034334	adherens junction maintenance(GO:0034334)
0.3	0.3	GO:0016081	synaptic vesicle docking(GO:0016081)
0.3	0.8	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.3	1.1	GO:0030807	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.3	1.6	GO:0051012	microtubule sliding(GO:0051012)
0.3	2.1	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3	0.5	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.3	0.8	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.3	0.5	GO:0002001	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.3	0.8	GO:1990108	protein linear deubiquitination(GO:1990108)
0.3	0.3	GO:0032472	Golgi calcium ion transport(GO:0032472)
0.3	0.8	GO:0014735	regulation of muscle atrophy(GO:0014735) negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876)
0.3	0.3	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.3	2.9	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.3	3.4	GO:0071397	cellular response to cholesterol(GO:0071397)
0.3	6.9	GO:0043968	histone H2A acetylation(GO:0043968)
0.3	0.5	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.3	0.8	GO:0045210	FasL biosynthetic process(GO:0045210)
0.3	5.5	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.3	1.8	GO:0006531	aspartate metabolic process(GO:0006531)
0.3	2.1	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.3	0.3	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.3	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.3	0.5	GO:0006382	adenosine to inosine editing(GO:0006382)
0.3	0.3	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.3	2.6	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.3	0.5	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.3	7.2	GO:0070987	error-free translesion synthesis(GO:0070987)
0.3	1.0	GO:0032273	positive regulation of protein polymerization(GO:0032273)
0.3	7.7	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.3	0.3	GO:0006271	DNA strand elongation involved in DNA replication(GO:0006271)
0.3	1.5	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.3	1.3	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.3	0.5	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.3	0.8	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.3	0.3	GO:0060081	membrane hyperpolarization(GO:0060081)
0.3	1.3	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.3	1.5	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.3	0.3	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.3	3.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.3	0.3	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.3	3.0	GO:0035372	protein localization to microtubule(GO:0035372)
0.2	0.2	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.2	1.2	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2	2.0	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.2	2.0	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2	1.2	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2	1.0	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.2	0.5	GO:0016045	detection of bacterium(GO:0016045)
0.2	1.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.2	3.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2	0.5	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.2	0.5	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.2	0.7	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.2	0.7	GO:0021559	trigeminal nerve development(GO:0021559)
0.2	0.7	GO:0050894	determination of affect(GO:0050894)
0.2	0.7	GO:0090527	actin filament reorganization(GO:0090527)
0.2	0.2	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.2	1.0	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.2	1.2	GO:0033128	negative regulation of histone phosphorylation(GO:0033128)
0.2	1.5	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
0.2	0.7	GO:0044467	glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.2	0.2	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.2	1.0	GO:0090045	positive regulation of deacetylase activity(GO:0090045)
0.2	0.7	GO:0035723	interleukin-15-mediated signaling pathway(GO:0035723) extrathymic T cell selection(GO:0045062) cellular response to interleukin-15(GO:0071350) regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2	0.7	GO:0030451	regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.2	1.7	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2	0.2	GO:0048733	sebaceous gland development(GO:0048733)
0.2	0.7	GO:0051311	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.2	0.2	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241)
0.2	0.2	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.2	1.4	GO:0042747	circadian sleep/wake cycle, REM sleep(GO:0042747)
0.2	0.2	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.2	0.9	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2	0.5	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.2	0.9	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.2	0.2	GO:0042220	response to cocaine(GO:0042220)
0.2	1.4	GO:0071321	cellular response to cGMP(GO:0071321)
0.2	0.7	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2	0.5	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.2	3.5	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.2	14.0	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.2	2.7	GO:0007220	Notch receptor processing(GO:0007220)
0.2	6.9	GO:0097435	fibril organization(GO:0097435)
0.2	2.3	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2	0.5	GO:0060796	regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.2	0.5	GO:0032486	Rap protein signal transduction(GO:0032486)
0.2	3.2	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.2	0.5	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2	0.5	GO:0016129	phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.2	0.2	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.2	3.4	GO:0000338	protein deneddylation(GO:0000338)
0.2	1.1	GO:0006541	glutamine metabolic process(GO:0006541)
0.2	1.8	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.2	0.9	GO:0007619	courtship behavior(GO:0007619)
0.2	0.9	GO:0070841	inclusion body assembly(GO:0070841)
0.2	0.2	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.2	1.8	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.2	1.1	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.2	1.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2	0.2	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.2	1.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.2	1.3	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.2	0.7	GO:1902017	regulation of cilium assembly(GO:1902017)
0.2	0.4	GO:0015670	carbon dioxide transport(GO:0015670)
0.2	0.7	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.2	0.7	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2	0.2	GO:0060992	response to fungicide(GO:0060992)
0.2	12.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.2	1.1	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.2	0.7	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.2	2.6	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2	6.3	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.2	8.8	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.2	0.9	GO:0000076	DNA replication checkpoint(GO:0000076)
0.2	0.9	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2	1.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.2	0.4	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2	3.0	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441)
0.2	0.4	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	0.4	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.2	0.2	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.2	0.2	GO:0000255	allantoin metabolic process(GO:0000255)
0.2	1.5	GO:0045995	regulation of embryonic development(GO:0045995)
0.2	1.7	GO:0001711	endodermal cell fate commitment(GO:0001711)
0.2	0.2	GO:0070305	response to cGMP(GO:0070305)
0.2	1.1	GO:0044362	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) modification by host of symbiont molecular function(GO:0052428)
0.2	0.6	GO:0001866	NK T cell proliferation(GO:0001866)
0.2	0.4	GO:0010155	regulation of proton transport(GO:0010155)
0.2	0.8	GO:0006226	dUMP biosynthetic process(GO:0006226)
0.2	1.5	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.2	0.4	GO:0006404	RNA import into nucleus(GO:0006404)
0.2	0.2	GO:0016246	RNA interference(GO:0016246)
0.2	0.8	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2	4.2	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.2	0.2	GO:0001768	establishment of T cell polarity(GO:0001768)
0.2	0.2	GO:0038034	signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.2	0.4	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2	0.8	GO:0090647	modulation of age-related behavioral decline(GO:0090647)
0.2	1.3	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.2	0.2	GO:0098877	neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.2	2.7	GO:0015732	prostaglandin transport(GO:0015732)
0.2	1.5	GO:0002692	negative regulation of cellular extravasation(GO:0002692)
0.2	1.4	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.2	5.6	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.2	0.6	GO:0009597	detection of virus(GO:0009597)
0.2	1.0	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.2	6.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2	0.4	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.2	0.6	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.2	0.4	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.2	1.8	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.2	0.2	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.2	0.6	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2	0.6	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.2	1.0	GO:0032418	lysosome localization(GO:0032418)
0.2	0.8	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.2	1.4	GO:0046618	drug export(GO:0046618)
0.2	0.4	GO:0002572	pro-T cell differentiation(GO:0002572)
0.2	0.6	GO:0048511	rhythmic process(GO:0048511)
0.2	0.4	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2	1.0	GO:0007028	cytoplasm organization(GO:0007028)
0.2	0.4	GO:0042116	macrophage activation(GO:0042116)
0.2	0.2	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2	0.4	GO:0032570	response to progesterone(GO:0032570)
0.2	0.4	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2	0.6	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2	0.2	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.2	0.6	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.2	1.2	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.2	0.4	GO:0038178	complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.2	0.4	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
0.2	0.6	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.2	9.9	GO:0016266	O-glycan processing(GO:0016266)
0.2	0.2	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.2	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.2	0.4	GO:0006110	regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811)
0.2	1.4	GO:0030091	protein repair(GO:0030091)
0.2	1.0	GO:0030522	intracellular receptor signaling pathway(GO:0030522)
0.2	0.4	GO:0043489	RNA stabilization(GO:0043489)
0.2	0.4	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.2	0.8	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.2	1.3	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.2	0.2	GO:0009651	response to salt stress(GO:0009651)
0.2	0.4	GO:0000305	response to oxygen radical(GO:0000305)
0.2	1.1	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	1.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.2	0.8	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.2	1.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.2	0.9	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.2	0.2	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115)
0.2	0.4	GO:0009227	UDP-glucose catabolic process(GO:0006258) nucleotide-sugar catabolic process(GO:0009227)
0.2	0.2	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.2	0.4	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2	1.3	GO:0001878	response to yeast(GO:0001878)
0.2	0.9	GO:0089712	L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.2	0.2	GO:0009441	glycolate metabolic process(GO:0009441)
0.2	0.9	GO:0045338	farnesyl diphosphate metabolic process(GO:0045338)
0.2	1.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	0.2	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.2	0.9	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.2	6.1	GO:0006739	NADP metabolic process(GO:0006739)
0.2	0.6	GO:0050917	sensory perception of umami taste(GO:0050917)
0.2	0.2	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.2	1.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.2	0.6	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.2	2.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2	0.4	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2	0.4	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.2	1.1	GO:0006308	DNA catabolic process(GO:0006308)
0.2	0.9	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.2	0.4	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.2	0.7	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.2	1.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.2	0.2	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.2	0.4	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2	2.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2	0.5	GO:0051697	protein delipidation(GO:0051697)
0.2	0.5	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.2	3.4	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.2	0.7	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.2	0.2	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	0.2	GO:0002644	negative regulation of tolerance induction(GO:0002644)
0.2	0.9	GO:0035926	chemokine (C-C motif) ligand 2 secretion(GO:0035926)
0.2	1.2	GO:0015693	magnesium ion transport(GO:0015693)
0.2	0.5	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2	0.2	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.2	1.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2	1.4	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.2	1.6	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.2	1.1	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2	1.1	GO:2001300	lipoxin metabolic process(GO:2001300)
0.2	0.7	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	0.2	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2	0.7	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.2	0.2	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.2	0.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.2	0.7	GO:1904046	negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2	0.2	GO:0038001	paracrine signaling(GO:0038001)
0.2	0.5	GO:0009447	putrescine catabolic process(GO:0009447)
0.2	0.5	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2	0.2	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2	0.7	GO:0000012	single strand break repair(GO:0000012)
0.2	0.2	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.2	0.5	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2	0.3	GO:0055099	detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.2	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	0.3	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.2	0.5	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.2	0.5	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2	0.5	GO:0086100	endothelin receptor signaling pathway(GO:0086100)
0.2	0.5	GO:0010002	cardioblast differentiation(GO:0010002)
0.2	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.2	0.2	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2	0.2	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.2	0.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.2	2.9	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2	0.2	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.2	0.2	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.2	0.3	GO:0048102	autophagic cell death(GO:0048102)
0.2	0.2	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.2	0.5	GO:0036018	cellular response to erythropoietin(GO:0036018)
0.2	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.2	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.2	0.3	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.2	1.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.2	2.6	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.2	5.6	GO:0060396	growth hormone receptor signaling pathway(GO:0060396)
0.2	1.6	GO:0006600	creatine metabolic process(GO:0006600)
0.2	2.5	GO:0046688	response to copper ion(GO:0046688)
0.2	1.8	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.2	1.0	GO:0042407	cristae formation(GO:0042407)
0.2	1.0	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.2	1.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.2	0.3	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.2	1.0	GO:0060701	regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2	0.7	GO:0010814	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2	1.1	GO:0014029	neural crest formation(GO:0014029)
0.2	0.3	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.2	0.5	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2	0.2	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2	0.8	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.2	0.3	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.2	0.2	GO:0035588	G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2	0.8	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	0.3	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.2	0.6	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.2	0.3	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.2	0.6	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2	4.0	GO:0010107	potassium ion import(GO:0010107)
0.2	0.3	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.2	1.9	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.2	0.3	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.2	2.7	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.2	5.0	GO:0090382	phagosome maturation(GO:0090382)
0.2	3.9	GO:0006101	citrate metabolic process(GO:0006101)
0.2	0.3	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.2	0.5	GO:1904646	cellular response to beta-amyloid(GO:1904646)
0.2	4.8	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2	5.4	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.2	0.2	GO:0021772	olfactory bulb development(GO:0021772)
0.2	1.2	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.2	0.5	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581)
0.2	0.2	GO:0016233	telomere capping(GO:0016233)
0.2	0.3	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2	0.3	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
0.2	0.3	GO:0009386	translational attenuation(GO:0009386)
0.2	0.3	GO:0010888	negative regulation of lipid storage(GO:0010888) negative regulation of sequestering of triglyceride(GO:0010891)
0.2	0.3	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2	0.9	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.2	1.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	1.2	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.2	0.5	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.2	0.2	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.2	0.3	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.2	2.4	GO:0006012	galactose metabolic process(GO:0006012)
0.2	0.2	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2	0.5	GO:0060453	regulation of gastric acid secretion(GO:0060453)
0.2	0.5	GO:0016198	axon choice point recognition(GO:0016198)
0.2	0.5	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2	0.8	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.2	0.8	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.2	0.2	GO:0099563	modification of synaptic structure(GO:0099563)
0.2	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.1	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.4	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.1	GO:0060613	fat pad development(GO:0060613)
0.1	1.3	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.1	9.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	0.4	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.1	1.6	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.1	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.1	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.7	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.1	0.6	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1	0.4	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1	0.3	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.1	1.9	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.1	8.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.1	GO:1905073	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1	0.3	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1	0.1	GO:0035627	ceramide transport(GO:0035627)
0.1	0.7	GO:0007635	chemosensory behavior(GO:0007635)
0.1	1.9	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.4	GO:0002818	intracellular defense response(GO:0002818)
0.1	1.7	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.1	0.9	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.1	0.3	GO:0030259	lipid glycosylation(GO:0030259)
0.1	0.7	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.1	0.4	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.1	1.6	GO:1900120	regulation of receptor binding(GO:1900120)
0.1	0.1	GO:0097647	dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1	0.4	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	2.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	11.8	GO:0006415	translational termination(GO:0006415)
0.1	0.7	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.1	0.3	GO:0000710	meiotic mismatch repair(GO:0000710)
0.1	0.4	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1	0.3	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1	0.3	GO:0032621	interleukin-18 production(GO:0032621)
0.1	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.4	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1	0.3	GO:0003358	noradrenergic neuron development(GO:0003358)
0.1	0.6	GO:2000811	negative regulation of anoikis(GO:2000811)
0.1	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	1.5	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.6	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.1	GO:0097491	sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1	2.5	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1	5.9	GO:1902305	regulation of sodium ion transmembrane transport(GO:1902305)
0.1	0.1	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296) regulation of mitochondrial DNA metabolic process(GO:1901858)
0.1	0.7	GO:0035865	cellular response to potassium ion(GO:0035865)
0.1	1.9	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.4	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1	0.1	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1	0.1	GO:0042756	drinking behavior(GO:0042756)
0.1	0.7	GO:0015074	DNA integration(GO:0015074)
0.1	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.1	0.4	GO:0031365	N-terminal protein amino acid modification(GO:0031365)
0.1	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	1.1	GO:0051095	regulation of helicase activity(GO:0051095)
0.1	1.6	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.3	GO:0036093	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1	0.4	GO:0070142	synaptic vesicle budding(GO:0070142)
0.1	0.3	GO:1900153	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1	0.1	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1	0.8	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.1	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1	0.4	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.5	GO:0048749	compound eye development(GO:0048749)
0.1	0.1	GO:0035524	proline transmembrane transport(GO:0035524)
0.1	3.0	GO:0060563	neuroepithelial cell differentiation(GO:0060563)
0.1	0.7	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.1	0.8	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.1	3.3	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.1	0.7	GO:1902001	fatty acid transmembrane transport(GO:1902001)
0.1	0.7	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	0.5	GO:0060849	radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1	1.4	GO:0007623	circadian rhythm(GO:0007623)
0.1	1.4	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	0.9	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.6	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	1.2	GO:0097264	self proteolysis(GO:0097264)
0.1	0.3	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.4	GO:0046931	pore complex assembly(GO:0046931)
0.1	0.4	GO:0035995	detection of muscle stretch(GO:0035995)
0.1	0.3	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.4	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.1	1.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.1	GO:0071910	determination of digestive tract left/right asymmetry(GO:0071907) determination of liver left/right asymmetry(GO:0071910)
0.1	0.5	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.4	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	0.3	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.1	0.5	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.6	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	0.3	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.3	GO:1902931	negative regulation of alcohol biosynthetic process(GO:1902931)
0.1	0.5	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483)
0.1	0.9	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.1	0.2	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.1	0.6	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1	0.4	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.4	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1	1.0	GO:0033692	cellular polysaccharide biosynthetic process(GO:0033692)
0.1	1.3	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1	0.1	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1	0.6	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.1	1.2	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.1	0.2	GO:1901355	response to rapamycin(GO:1901355)
0.1	0.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	3.7	GO:0032508	DNA duplex unwinding(GO:0032508)
0.1	0.7	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.1	1.8	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	1.7	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
0.1	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.1	7.3	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.1	0.6	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	2.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.1	0.1	GO:0043455	regulation of secondary metabolic process(GO:0043455)
0.1	0.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.1	2.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.3	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.1	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.1	0.3	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.1	0.9	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.5	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.1	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.1	0.8	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.3	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.1	1.3	GO:0042755	eating behavior(GO:0042755)
0.1	0.5	GO:0007341	penetration of zona pellucida(GO:0007341)
0.1	3.8	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.1	0.1	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.1	0.1	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.1	0.2	GO:0070541	response to platinum ion(GO:0070541)
0.1	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.1	0.1	GO:0090212	regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.1	0.1	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.1	0.2	GO:0031295	T cell costimulation(GO:0031295)
0.1	0.8	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.1	0.3	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.1	0.4	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	1.0	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1	0.2	GO:0035864	response to potassium ion(GO:0035864)
0.1	0.4	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	0.3	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	0.4	GO:0031023	microtubule organizing center organization(GO:0031023)
0.1	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	1.3	GO:0048017	inositol lipid-mediated signaling(GO:0048017)
0.1	0.2	GO:0043449	cellular alkene metabolic process(GO:0043449)
0.1	0.3	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	3.6	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	0.9	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.1	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.1	0.4	GO:0060482	lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1	0.1	GO:0043624	cellular protein complex disassembly(GO:0043624)
0.1	0.1	GO:1901374	acetate ester transport(GO:1901374)
0.1	0.1	GO:0071468	cellular response to acidic pH(GO:0071468)
0.1	1.3	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.1	2.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	2.3	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1	0.3	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.1	0.9	GO:0035067	negative regulation of histone acetylation(GO:0035067)
0.1	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.1	0.2	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.1	0.1	GO:0009204	deoxyribonucleoside triphosphate catabolic process(GO:0009204)
0.1	0.4	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.5	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1	0.2	GO:0036034	mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1	0.3	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1	0.6	GO:0007506	gonadal mesoderm development(GO:0007506)
0.1	0.1	GO:0097327	response to antineoplastic agent(GO:0097327)
0.1	2.1	GO:0007265	Ras protein signal transduction(GO:0007265)
0.1	0.3	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
0.1	0.5	GO:0015747	urate transport(GO:0015747)
0.1	0.8	GO:0016180	snRNA processing(GO:0016180)
0.1	0.7	GO:0030252	growth hormone secretion(GO:0030252)
0.1	0.7	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	1.4	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	1.8	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	0.1	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1	0.3	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.1	1.2	GO:0030431	sleep(GO:0030431)
0.1	0.7	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	3.4	GO:0046785	microtubule polymerization(GO:0046785)
0.1	1.8	GO:0007141	male meiosis I(GO:0007141)
0.1	0.2	GO:0071774	response to fibroblast growth factor(GO:0071774)
0.1	1.8	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	0.1	GO:0036090	cleavage furrow ingression(GO:0036090)
0.1	0.2	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	6.2	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.1	0.3	GO:0071888	macrophage apoptotic process(GO:0071888)
0.1	0.5	GO:0006265	DNA topological change(GO:0006265)
0.1	0.2	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1	0.7	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.1	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1	0.5	GO:0097267	omega-hydroxylase P450 pathway(GO:0097267)
0.1	0.3	GO:0036491	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1	0.4	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.4	GO:0051958	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.5	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.1	1.5	GO:0006298	mismatch repair(GO:0006298)
0.1	0.5	GO:1903321	negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.1	0.3	GO:0035092	sperm chromatin condensation(GO:0035092)
0.1	0.8	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.1	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1	0.5	GO:0051775	response to redox state(GO:0051775)
0.1	1.3	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.1	0.4	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1	0.9	GO:0036035	osteoclast development(GO:0036035)
0.1	2.0	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.1	0.8	GO:0048853	forebrain morphogenesis(GO:0048853)
0.1	0.3	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.1	0.3	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.1	0.9	GO:1901072	glucosamine-containing compound catabolic process(GO:1901072)
0.1	0.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.1	2.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	8.0	GO:0015992	proton transport(GO:0015992)
0.1	0.2	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.1	GO:0044108	cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.1	0.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	1.1	GO:0007140	male meiosis(GO:0007140)
0.1	0.5	GO:2000194	regulation of female gonad development(GO:2000194)
0.1	0.8	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	0.1	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.3	GO:0045598	regulation of fat cell differentiation(GO:0045598)
0.1	0.9	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.4	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	2.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	0.2	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.1	0.3	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	0.7	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1	0.3	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.1	0.2	GO:0001757	somite specification(GO:0001757)
0.1	0.6	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.1	0.3	GO:0021814	cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.1	0.2	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.1	0.7	GO:1903020	positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.2	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027) negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	1.1	GO:0001502	cartilage condensation(GO:0001502)
0.1	0.2	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1	0.6	GO:0042461	photoreceptor cell development(GO:0042461)
0.1	0.6	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.1	0.2	GO:0036124	histone H3-K9 trimethylation(GO:0036124)
0.1	0.1	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.1	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	0.5	GO:0070475	rRNA base methylation(GO:0070475)
0.1	0.1	GO:0090670	RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672)
0.1	0.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.1	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.1	0.1	GO:0055095	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1	0.2	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	0.3	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.1	1.3	GO:0003351	epithelial cilium movement(GO:0003351)
0.1	0.5	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.2	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1	0.2	GO:0060612	adipose tissue development(GO:0060612)
0.1	0.1	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1	0.9	GO:0045116	protein neddylation(GO:0045116)
0.1	1.2	GO:0043401	steroid hormone mediated signaling pathway(GO:0043401)
0.1	0.9	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	1.2	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.1	0.5	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1	0.6	GO:0048854	brain morphogenesis(GO:0048854)
0.1	0.4	GO:0003360	brainstem development(GO:0003360)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.2	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	1.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.9	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.1	0.4	GO:0003091	renal water homeostasis(GO:0003091)
0.1	0.7	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.1	0.3	GO:0050928	Tie signaling pathway(GO:0048014) negative regulation of positive chemotaxis(GO:0050928)
0.1	1.0	GO:0019054	modulation by virus of host process(GO:0019054)
0.1	0.3	GO:0002638	negative regulation of immunoglobulin production(GO:0002638)
0.1	0.2	GO:1902490	regulation of sperm capacitation(GO:1902490)
0.1	0.2	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.2	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1	1.6	GO:0038202	TORC1 signaling(GO:0038202)
0.1	0.1	GO:0002384	hepatic immune response(GO:0002384)
0.1	1.2	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.1	0.4	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1	0.2	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1	0.1	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	0.9	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1	0.1	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	1.0	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1	0.5	GO:0001967	suckling behavior(GO:0001967)
0.1	0.4	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.1	1.3	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.1	3.4	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1	0.1	GO:0060346	bone trabecula formation(GO:0060346)
0.1	0.1	GO:0002024	diet induced thermogenesis(GO:0002024)
0.1	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.1	0.6	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187)
0.1	0.4	GO:0023058	adaptation of signaling pathway(GO:0023058)
0.1	0.2	GO:1901317	regulation of sperm motility(GO:1901317)
0.1	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	0.5	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	0.4	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.1	0.4	GO:0003341	cilium movement(GO:0003341)
0.1	0.8	GO:0019722	calcium-mediated signaling(GO:0019722)
0.1	0.1	GO:0070781	response to biotin(GO:0070781)
0.1	0.2	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	0.1	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.1	0.3	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.1	1.0	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.1	0.2	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.1	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.4	GO:0007625	grooming behavior(GO:0007625)
0.1	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.1	0.2	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.1	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.1	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.1	0.7	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.1	0.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.1	GO:1901655	cellular response to ketone(GO:1901655)
0.1	0.1	GO:0000055	ribosomal subunit export from nucleus(GO:0000054) ribosomal large subunit export from nucleus(GO:0000055) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.1	1.0	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1	4.1	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1	0.1	GO:0009624	response to nematode(GO:0009624)
0.1	0.4	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919)
0.1	0.1	GO:0002586	regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1	0.1	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1	0.2	GO:0032461	positive regulation of protein oligomerization(GO:0032461) positive regulation of protein homooligomerization(GO:0032464)
0.1	0.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	1.2	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.1	1.0	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.1	0.3	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.1	2.7	GO:0007602	phototransduction(GO:0007602)
0.1	0.4	GO:0031167	rRNA methylation(GO:0031167)
0.1	0.2	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.9	GO:0002183	cytoplasmic translational initiation(GO:0002183)
0.1	0.1	GO:0043634	polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.1	0.2	GO:0021511	spinal cord patterning(GO:0021511)
0.1	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.1	1.7	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.1	0.7	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1	0.1	GO:1905146	lysosomal protein catabolic process(GO:1905146)
0.1	0.6	GO:0022900	electron transport chain(GO:0022900)
0.1	0.1	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.1	0.2	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.3	GO:0030238	male sex determination(GO:0030238)
0.1	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	0.1	GO:0032091	negative regulation of protein binding(GO:0032091)
0.1	0.3	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.1	0.3	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.1	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	0.1	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	0.2	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.4	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.2	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.1	0.2	GO:1902172	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1	0.5	GO:1901070	guanosine-containing compound biosynthetic process(GO:1901070)
0.1	0.1	GO:0071105	response to interleukin-11(GO:0071105)
0.1	0.2	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1	0.6	GO:0019363	nicotinamide nucleotide biosynthetic process(GO:0019359) pyridine nucleotide biosynthetic process(GO:0019363)
0.1	0.2	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	0.1	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1	0.4	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.1	0.2	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.1	0.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.2	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.1	0.2	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.1	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.3	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.5	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:2000757	negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0	0.8	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.2	GO:0060571	morphogenesis of an epithelial fold(GO:0060571)
0.0	0.1	GO:0043201	response to leucine(GO:0043201)
0.0	1.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.6	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.4	GO:0002475	antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.4	GO:0070507	regulation of microtubule cytoskeleton organization(GO:0070507)
0.0	0.3	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.3	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	3.6	GO:0051054	positive regulation of DNA metabolic process(GO:0051054)
0.0	0.1	GO:1900154	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0	0.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.0	GO:0032611	interleukin-1 beta production(GO:0032611)
0.0	3.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0060405	regulation of penile erection(GO:0060405)
0.0	2.6	GO:0050871	positive regulation of B cell activation(GO:0050871)
0.0	0.1	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.0	1.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.3	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
0.0	0.1	GO:0003218	cardiac left ventricle formation(GO:0003218)
0.0	0.0	GO:1902742	apoptotic process involved in morphogenesis(GO:0060561) apoptotic process involved in development(GO:1902742)
0.0	0.5	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0031860	telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860)
0.0	0.1	GO:0061450	trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
0.0	0.2	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0	0.0	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0050893	sensory processing(GO:0050893)
0.0	0.6	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.2	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	3.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.0	GO:0061117	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of heart growth(GO:0061117)
0.0	0.6	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.0	GO:0007127	meiosis I(GO:0007127)
0.0	0.2	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.1	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.1	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:0090656	t-circle formation(GO:0090656)
0.0	0.3	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0	0.3	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0021759	globus pallidus development(GO:0021759)
0.0	0.1	GO:0099525	presynaptic dense core granule exocytosis(GO:0099525)
0.0	0.2	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.4	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.6	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0001575	globoside metabolic process(GO:0001575)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	1.7	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	1.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.1	GO:0002005	angiotensin catabolic process in blood(GO:0002005)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.4	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.0	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.0	0.3	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.4	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.3	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:0070316	regulation of G0 to G1 transition(GO:0070316)
0.0	0.0	GO:0070170	regulation of tooth mineralization(GO:0070170)
0.0	0.2	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	1.0	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.0	GO:0002331	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.0	0.2	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.1	GO:1904645	response to beta-amyloid(GO:1904645)
0.0	0.0	GO:0009953	dorsal/ventral pattern formation(GO:0009953)
0.0	0.2	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.1	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.3	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.0	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.3	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
0.0	0.1	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.1	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.0	0.1	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.4	GO:0006284	base-excision repair(GO:0006284)
0.0	0.1	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.2	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.4	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0	0.0	GO:0043506	regulation of JUN kinase activity(GO:0043506)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.2	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.0	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.0	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.3	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0050918	positive chemotaxis(GO:0050918)
0.0	0.4	GO:0051058	negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.0	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.0	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.0	GO:0072595	maintenance of protein localization in organelle(GO:0072595)
0.0	0.1	GO:1901862	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0	0.1	GO:0070166	enamel mineralization(GO:0070166)
0.0	0.1	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.0	GO:0001555	oocyte growth(GO:0001555)
0.0	0.0	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.0	GO:2001026	regulation of endothelial cell chemotaxis(GO:2001026)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.2	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.0	GO:1901186	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.0	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.0	0.1	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	0.0	GO:1902573	positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.0	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.0	0.0	GO:0044268	multicellular organismal protein metabolic process(GO:0044268)
0.0	0.0	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.0	GO:0051797	regulation of hair follicle development(GO:0051797)
0.0	0.1	GO:0032660	regulation of interleukin-17 production(GO:0032660)
0.0	0.1	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0002765	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.0	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0	0.0	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.0	GO:0044090	positive regulation of vacuole organization(GO:0044090)
0.0	0.0	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.0	0.1	GO:0003322	pancreatic A cell development(GO:0003322)
0.0	0.0	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.0	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.0	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.0	0.0	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.0	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0	0.0	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392)
0.0	0.0	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0	0.0	GO:0035747	natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte chemotaxis(GO:1901624) negative regulation of lymphocyte migration(GO:2000402)
0.0	0.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	3.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	1.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.0	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	4.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	1.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	4.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	4.5	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.6	1.9	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.3	6.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.3	1.0	GO:0031417	NatC complex(GO:0031417)
0.3	1.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.3	1.8	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.3	2.4	GO:0031931	TORC1 complex(GO:0031931)
0.3	1.7	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.3	1.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	1.7	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2	1.9	GO:0005610	laminin-5 complex(GO:0005610)
0.2	1.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2	2.7	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.2	0.7	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.2	0.4	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2	1.1	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.2	1.7	GO:1990111	spermatoproteasome complex(GO:1990111)
0.2	1.0	GO:0031905	early endosome lumen(GO:0031905)
0.2	0.8	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	2.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.2	0.6	GO:0030689	Noc complex(GO:0030689)
0.2	1.0	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.2	1.0	GO:0034457	Mpp10 complex(GO:0034457)
0.2	2.7	GO:0035631	CD40 receptor complex(GO:0035631)
0.2	0.7	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.2	0.7	GO:1990031	pinceau fiber(GO:1990031)
0.2	0.5	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.2	1.0	GO:0090661	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.2	0.6	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	1.6	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	0.2	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	0.6	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	1.3	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.9	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	1.4	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.1	0.7	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	0.6	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1	1.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	0.4	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1	0.4	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1	0.6	GO:0001739	sex chromatin(GO:0001739)
0.1	1.5	GO:0042555	MCM complex(GO:0042555)
0.1	1.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	1.0	GO:0098845	postsynaptic endosome(GO:0098845)
0.1	0.5	GO:0005667	transcription factor complex(GO:0005667)
0.1	0.4	GO:0034657	GID complex(GO:0034657)
0.1	0.1	GO:0005876	spindle microtubule(GO:0005876)
0.1	0.4	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	0.4	GO:0032301	MutSalpha complex(GO:0032301)
0.1	0.5	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.1	0.4	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.1	2.1	GO:0000812	Swr1 complex(GO:0000812)
0.1	0.5	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.3	GO:0043291	RAVE complex(GO:0043291)
0.1	0.7	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.4	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.6	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	0.7	GO:0033269	internode region of axon(GO:0033269)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.4	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.1	0.3	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	0.3	GO:0070195	growth hormone receptor complex(GO:0070195)
0.1	1.7	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	0.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	1.4	GO:0097346	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.1	0.8	GO:0032039	integrator complex(GO:0032039)
0.1	0.3	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.1	1.0	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	2.6	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	2.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.6	GO:0061617	MICOS complex(GO:0061617)
0.1	0.2	GO:0036398	TCR signalosome(GO:0036398)
0.1	0.2	GO:0005960	glycine cleavage complex(GO:0005960)
0.1	0.2	GO:0070557	PCNA-p21 complex(GO:0070557)
0.1	0.2	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1	0.6	GO:0000125	PCAF complex(GO:0000125)
0.1	0.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	1.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	0.5	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	0.2	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)
0.1	0.7	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	3.0	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	0.2	GO:0001740	X chromosome(GO:0000805) Barr body(GO:0001740)
0.1	0.3	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.4	GO:0002080	acrosomal membrane(GO:0002080)
0.1	1.6	GO:0046930	pore complex(GO:0046930)
0.1	1.0	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.1	GO:0070821	tertiary granule membrane(GO:0070821)
0.1	1.6	GO:0071564	npBAF complex(GO:0071564)
0.1	0.2	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	1.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.5	GO:0097427	microtubule bundle(GO:0097427)
0.1	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.4	GO:0030905	retromer, tubulation complex(GO:0030905)
0.1	0.1	GO:0044798	nuclear transcription factor complex(GO:0044798)
0.1	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.3	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.1	0.3	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.1	0.1	GO:0030137	COPI-coated vesicle(GO:0030137)
0.1	0.8	GO:0045120	pronucleus(GO:0045120)
0.1	0.4	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.7	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	0.4	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.4	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.6	GO:0044327	dendritic spine head(GO:0044327)
0.1	0.3	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.1	0.4	GO:0042382	paraspeckles(GO:0042382)
0.1	0.7	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.3	GO:1990769	proximal neuron projection(GO:1990769)
0.1	0.5	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	0.4	GO:0070187	telosome(GO:0070187)
0.1	0.2	GO:0070695	FHF complex(GO:0070695)
0.1	0.1	GO:0032807	DNA ligase IV complex(GO:0032807)
0.1	0.5	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.7	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	0.2	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.2	GO:1990298	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1	0.4	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.6	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	0.3	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	6.8	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.4	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0034455	t-UTP complex(GO:0034455)
0.0	1.3	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.8	GO:0034709	methylosome(GO:0034709)
0.0	0.7	GO:0030686	90S preribosome(GO:0030686)
0.0	0.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	1.1	GO:0032156	septin cytoskeleton(GO:0032156)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	2.3	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.5	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.9	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.5	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.3	GO:0000322	storage vacuole(GO:0000322)
0.0	0.6	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.2	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0044423	virion(GO:0019012) virion part(GO:0044423)
0.0	0.4	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0070470	plasma membrane respiratory chain(GO:0070470)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.6	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.2	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	3.4	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.3	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.3	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.3	GO:0000800	lateral element(GO:0000800)
0.0	0.7	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.3	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	0.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.6	GO:0005922	connexon complex(GO:0005922)
0.0	0.4	GO:0016600	flotillin complex(GO:0016600)
0.0	1.1	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.3	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.7	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.4	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.6	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	10.4	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.2	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.5	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.3	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.3	GO:0000243	commitment complex(GO:0000243)
0.0	0.1	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	0.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	1.3	GO:0016235	aggresome(GO:0016235)
0.0	0.8	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	1.1	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	3.5	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.2	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.2	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.3	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.4	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0	0.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.6	GO:0034451	centriolar satellite(GO:0034451)
0.0	4.5	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.7	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.1	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	1.0	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	1.3	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.6	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.3	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	0.2	GO:0045171	intercellular bridge(GO:0045171)
0.0	1.0	GO:0043025	neuronal cell body(GO:0043025)
0.0	0.1	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.6	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0097422	retromer, cargo-selective complex(GO:0030906) tubular endosome(GO:0097422)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.3	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	4.7	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.7	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.1	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.6	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.3	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.5	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.2	GO:0030018	Z disc(GO:0030018)
0.0	0.7	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.3	GO:0005871	kinesin complex(GO:0005871)
0.0	0.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	1.7	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.9	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	2.2	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	1.7	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.0	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.0	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	0.1	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.0	0.0	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.4	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.0	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.5	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0	0.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0005607	laminin-2 complex(GO:0005607)
0.7	2.0	GO:0005608	laminin-3 complex(GO:0005608)
0.5	4.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.5	2.0	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.4	1.3	GO:0005588	collagen type V trimer(GO:0005588)
0.4	5.5	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4	5.6	GO:0030478	actin cap(GO:0030478)
0.3	1.0	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.3	0.8	GO:0044609	DBIRD complex(GO:0044609)
0.3	1.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	3.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	1.2	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2	1.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2	1.9	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	0.4	GO:0016011	dystroglycan complex(GO:0016011)
0.2	2.6	GO:0005577	fibrinogen complex(GO:0005577)
0.2	0.8	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2	1.3	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	1.0	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.7	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	1.9	GO:0042583	chromaffin granule(GO:0042583)
0.1	1.4	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	9.5	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.9	GO:0097512	cardiac myofibril(GO:0097512)
0.1	2.3	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.1	0.3	GO:0097441	basilar dendrite(GO:0097441)
0.1	1.0	GO:0043218	compact myelin(GO:0043218)
0.1	0.6	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.4	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	0.4	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.1	0.5	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	1.6	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	1.3	GO:0097342	ripoptosome(GO:0097342)
0.1	0.9	GO:0044327	dendritic spine head(GO:0044327)
0.1	0.4	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	0.4	GO:1990037	Lewy body core(GO:1990037)
0.1	1.7	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	0.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.3	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	2.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	0.3	GO:0071546	pi-body(GO:0071546)
0.1	0.9	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.1	0.6	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.1	0.6	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.2	GO:1990745	EARP complex(GO:1990745)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.6	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0070852	cell body fiber(GO:0070852)
0.0	0.9	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.8	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.9	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.0	1.0	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.3	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0	3.3	GO:0043195	terminal bouton(GO:0043195)
0.0	3.6	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0031905	early endosome lumen(GO:0031905)
0.0	4.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.2	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.0	0.3	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0031310	intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.0	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.7	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	2.7	GO:0016459	myosin complex(GO:0016459)
0.0	0.7	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.2	GO:0033010	paranodal junction(GO:0033010)
0.0	0.3	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0036128	CatSper complex(GO:0036128)
0.0	2.2	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.1	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	2.0	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	2.7	GO:0043204	perikaryon(GO:0043204)
0.0	0.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	2.0	GO:0005901	caveola(GO:0005901)
0.0	3.6	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	2.4	GO:0008021	synaptic vesicle(GO:0008021)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	1.0	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	2.6	GO:0044449	contractile fiber part(GO:0044449)
0.0	0.4	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.0	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.7	GO:0030175	filopodium(GO:0030175)
0.0	0.0	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	0.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.5	GO:0005902	microvillus(GO:0005902)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	4.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.3	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.8	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	2.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.6	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	4.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.7	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	1.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.1	GO:0007412	axon target recognition(GO:0007412)
1.8	5.3	GO:0010645	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.1	3.2	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.8	2.5	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.5	2.5	GO:1990504	dense core granule exocytosis(GO:1990504)
0.5	7.5	GO:0006527	arginine catabolic process(GO:0006527)
0.3	1.3	GO:0016333	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.3	2.6	GO:0010265	SCF complex assembly(GO:0010265)
0.2	1.1	GO:0007623	circadian rhythm(GO:0007623)
0.2	0.9	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.2	0.8	GO:0051582	peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.2	3.7	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	1.5	GO:0070141	response to UV-A(GO:0070141)
0.1	0.7	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.6	GO:0006041	glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.4	GO:1904617	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1	0.4	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1	0.3	GO:0021836	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.1	3.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	1.3	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.1	2.0	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.8	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.1	2.2	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.8	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1	0.5	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.1	1.2	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.1	0.7	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	0.3	GO:0007619	courtship behavior(GO:0007619)
0.1	0.4	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.1	0.4	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	0.5	GO:0032264	IMP salvage(GO:0032264)
0.0	0.4	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	1.1	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	1.2	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.8	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.0	1.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.3	GO:0098707	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0	0.6	GO:2000117	negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0	0.3	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.4	GO:0002158	osteoclast proliferation(GO:0002158)
0.0	0.5	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	1.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	0.2	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	3.9	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.3	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.8	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.2	GO:1900113	histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
0.0	0.3	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	1.0	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	0.1	GO:0046929	negative regulation of neurotransmitter secretion(GO:0046929) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0	0.2	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.2	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.0	0.2	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	1.1	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.5	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.2	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.0	0.2	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.7	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	1.7	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	6.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.3	16.3	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	0.7	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
0.2	1.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.2	7.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.2	2.6	REACTOME LAGGING STRAND SYNTHESIS	Genes involved in Lagging Strand Synthesis
0.2	3.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	0.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	1.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	1.5	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	2.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	3.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.4	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.1	3.3	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	0.7	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	2.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	1.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	1.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	2.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	0.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	2.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	8.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	2.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	1.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.7	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	1.0	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.7	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	1.2	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	1.5	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	2.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	4.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.6	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.6	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	1.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	1.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	1.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.7	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.5	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.6	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.6	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	1.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.5	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.5	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	1.0	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	8.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5	15.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	2.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	3.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.0	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	0.9	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.6	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	2.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	29.9	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
1.0	26.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.8	11.9	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4	6.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.4	7.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.3	5.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2	12.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	1.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.2	1.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	2.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	2.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	12.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	5.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	1.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	1.3	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	2.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	2.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.9	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	2.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	4.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.0	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.0	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	13.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.3	4.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	4.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	4.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	3.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	3.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	0.9	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	3.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.0	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	1.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.0	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	1.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	2.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.7	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.7	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.7	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	1.6	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
1.4	23.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.1	16.9	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
1.1	6.5	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
1.0	29.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
1.0	16.9	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
1.0	25.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.8	16.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.8	8.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.8	3.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.8	9.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.8	1.6	REACTOME SIGNALING BY INSULIN RECEPTOR	Genes involved in Signaling by Insulin receptor
0.7	12.9	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.7	18.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.7	9.7	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.7	26.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.7	3.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.7	25.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.6	8.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.6	17.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.6	7.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.6	13.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.6	22.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.6	4.7	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.6	10.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.6	12.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.5	23.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.5	1.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.5	1.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.5	12.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.5	3.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.5	5.8	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.5	12.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.4	8.8	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.4	12.6	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.4	0.9	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4	9.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	5.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.4	22.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.4	9.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.4	10.8	REACTOME KINESINS	Genes involved in Kinesins
0.4	2.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.4	7.8	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.4	7.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.4	2.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.4	2.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.4	10.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4	6.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.4	7.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.4	5.7	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.4	3.8	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.4	7.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.4	0.7	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.4	5.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.4	6.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.4	8.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.4	0.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.3	5.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.3	8.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3	2.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.3	20.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3	3.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	6.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	6.0	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.3	45.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.3	5.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.3	7.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	5.9	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3	1.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.3	5.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3	10.7	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.3	7.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.3	7.9	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.3	20.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.3	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.3	2.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	5.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3	10.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.3	0.6	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.3	7.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.3	1.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3	1.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.3	0.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	14.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	2.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3	11.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.3	7.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.3	6.7	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.3	1.6	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.3	8.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.3	3.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3	6.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.3	8.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	5.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.3	13.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	0.5	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.2	14.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2	2.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	0.5	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.2	3.6	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	2.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	4.8	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.2	20.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.2	0.9	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.2	2.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	3.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	1.8	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.2	1.8	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.2	2.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.2	2.9	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.2	4.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.2	1.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	4.8	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.2	2.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.2	6.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.2	2.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2	2.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	10.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.2	12.7	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.2	3.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	8.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	1.4	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.2	6.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.2	37.3	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.2	0.8	REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS	Genes involved in Metabolism of lipids and lipoproteins
0.2	1.7	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.2	1.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.2	2.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.2	7.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	5.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.2	6.7	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.2	4.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.2	1.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2	2.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.2	2.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.2	0.5	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.1	3.2	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1	3.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.3	REACTOME SIGNALING BY NOTCH	Genes involved in Signaling by NOTCH
0.1	0.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	40.4	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.1	3.0	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	0.5	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.1	12.9	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1	0.9	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	2.0	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	2.3	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	1.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	4.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	2.7	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	0.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	1.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	8.1	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1	0.5	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.1	2.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	1.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.6	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.1	2.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.2	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	4.7	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.1	10.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	0.3	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.1	3.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	5.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	0.2	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.1	1.6	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	0.1	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.1	0.7	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.9	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	7.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	2.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	1.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	0.5	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.0	0.4	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	1.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	1.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME INNATE IMMUNE SYSTEM	Genes involved in Innate Immune System
0.0	1.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	2.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.5	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	2.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.7	REACTOME RNA POL II TRANSCRIPTION	Genes involved in RNA Polymerase II Transcription
0.0	0.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.0	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.4	GO:0035995	detection of muscle stretch(GO:0035995)
0.3	1.0	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.1	1.3	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	1.0	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.4	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1	0.4	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1	0.5	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	0.3	GO:0001079	nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1	0.3	GO:1990641	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1	0.5	GO:0006540	glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.1	0.8	GO:0042118	regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) endothelial cell activation(GO:0042118)
0.1	0.8	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.6	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.1	1.9	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1	0.5	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.2	GO:0099541	retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0	0.7	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965) rRNA import into mitochondrion(GO:0035928)
0.0	0.2	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.4	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.2	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.3	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.3	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.3	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.0	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.0	0.6	GO:0051354	negative regulation of oxidoreductase activity(GO:0051354)
0.0	0.3	GO:0051608	histamine transport(GO:0051608)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0	0.0	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.1	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0	0.1	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.1	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	2.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	6.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	1.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	1.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	4.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	0.7	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	1.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	3.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	2.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.4	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	1.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.7	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.8	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	1.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	1.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.6	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.7	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	1.4	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
1.1	3.3	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
1.0	3.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.6	3.1	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6	2.4	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.5	3.2	GO:0090235	regulation of metaphase plate congression(GO:0090235)
0.5	2.5	GO:0042256	mature ribosome assembly(GO:0042256)
0.5	2.7	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.4	2.6	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.4	1.1	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.4	2.9	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4	1.1	GO:0000967	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.4	2.1	GO:0015853	adenine transport(GO:0015853)
0.3	1.0	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3	0.9	GO:0035283	rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3	1.2	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.3	0.9	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.3	2.0	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3	4.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.3	0.8	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.2	0.7	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.2	0.9	GO:0006272	leading strand elongation(GO:0006272)
0.2	0.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2	0.7	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.2	0.7	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.2	2.4	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.2	2.6	GO:0006108	malate metabolic process(GO:0006108)
0.2	0.4	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.2	2.5	GO:0006657	CDP-choline pathway(GO:0006657)
0.2	1.7	GO:0006552	leucine catabolic process(GO:0006552)
0.2	0.7	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.2	0.5	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.2	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	1.3	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.2	0.5	GO:0071301	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2	2.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.2	0.5	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2	0.8	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.2	0.8	GO:0051182	coenzyme transport(GO:0051182)
0.2	0.5	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	0.9	GO:0018343	protein farnesylation(GO:0018343)
0.1	2.5	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.1	0.4	GO:0006864	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1	0.4	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.7	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	0.5	GO:0042223	response to molecule of fungal origin(GO:0002238) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.1	0.4	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	1.7	GO:0015671	oxygen transport(GO:0015671)
0.1	1.3	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.7	GO:0035900	response to isolation stress(GO:0035900)
0.1	0.4	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	1.2	GO:0010265	SCF complex assembly(GO:0010265)
0.1	0.5	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	6.7	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.1	0.8	GO:1904044	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.1	1.0	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1	0.6	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.4	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.4	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.6	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	1.4	GO:1903405	protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1	0.3	GO:0072134	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133) nephrogenic mesenchyme morphogenesis(GO:0072134)
0.1	0.3	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.1	0.3	GO:0048382	mesendoderm development(GO:0048382)
0.1	0.3	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.5	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.4	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.3	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	1.4	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1	0.3	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	1.6	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.1	1.2	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.5	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	0.3	GO:0071030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.1	0.5	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.7	GO:0070475	rRNA base methylation(GO:0070475)
0.1	0.2	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.1	0.5	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.1	0.3	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.1	0.5	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	0.4	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1	0.5	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) regulation of receptor catabolic process(GO:2000644)
0.1	0.3	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1	0.4	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1	0.5	GO:0033504	floor plate development(GO:0033504)
0.1	2.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1	1.7	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.2	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.1	0.5	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.9	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.2	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.1	0.2	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.1	0.4	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.1	0.2	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	0.6	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.1	GO:0099553	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1	2.7	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	0.5	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.8	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.4	GO:0072642	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1	0.2	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.1	0.2	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.5	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.1	1.6	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1	0.5	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1	0.3	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.6	GO:0015791	polyol transport(GO:0015791)
0.1	0.2	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1	0.2	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1	1.4	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1	0.9	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.5	GO:0016584	nucleosome positioning(GO:0016584)
0.1	0.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.3	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.4	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.1	0.4	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.4	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.5	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	1.7	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.1	0.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	0.5	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1	0.1	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.5	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	1.4	GO:0051290	protein heterotetramerization(GO:0051290)
0.1	0.9	GO:0002021	response to dietary excess(GO:0002021)
0.1	0.2	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.1	0.1	GO:0015966	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1	0.7	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.1	0.9	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.5	GO:0006983	ER overload response(GO:0006983)
0.0	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.5	GO:0033227	dsRNA transport(GO:0033227)
0.0	1.8	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	1.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.5	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.5	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.1	GO:1990637	response to prolactin(GO:1990637)
0.0	0.5	GO:0015886	heme transport(GO:0015886)
0.0	0.5	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.5	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:0045905	translational frameshifting(GO:0006452) peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.4	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.7	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.6	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	1.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.2	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.5	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.6	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.6	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	1.2	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.5	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	2.8	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0	0.2	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.0	0.1	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.1	GO:0007518	myoblast fate determination(GO:0007518)
0.0	0.2	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.2	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289) regulation of Golgi inheritance(GO:0090170)
0.0	0.7	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.2	GO:0048667	cell morphogenesis involved in neuron differentiation(GO:0048667)
0.0	0.2	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.0	0.1	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0	2.4	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.7	GO:0002643	regulation of tolerance induction(GO:0002643)
0.0	0.5	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.3	GO:0002326	B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.3	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.3	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.3	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0	1.9	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.0	1.6	GO:0043069	negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069)
0.0	0.1	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.3	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.5	GO:0034724	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0	1.5	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.0	0.6	GO:0018105	peptidyl-serine phosphorylation(GO:0018105)
0.0	0.5	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.5	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.3	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.5	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.4	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.3	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0002183	cytoplasmic translational initiation(GO:0002183)
0.0	3.1	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	1.5	GO:0060416	response to growth hormone(GO:0060416)
0.0	0.5	GO:0051181	cofactor transport(GO:0051181)
0.0	1.0	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	1.1	GO:0035666	TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0	0.2	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.9	GO:0048538	thymus development(GO:0048538)
0.0	0.6	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.2	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.3	GO:0016051	carbohydrate biosynthetic process(GO:0016051)
0.0	0.5	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.0	0.3	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.5	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.6	GO:0035909	aorta morphogenesis(GO:0035909)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.3	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.1	GO:1903433	regulation of constitutive secretory pathway(GO:1903433)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.3	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.3	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.2	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.1	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.3	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.0	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0	0.3	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.3	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.7	GO:0006400	tRNA modification(GO:0006400)
0.0	0.8	GO:0005977	glycogen metabolic process(GO:0005977)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0001505	regulation of neurotransmitter levels(GO:0001505)
0.0	0.2	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.3	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0	0.1	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.2	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.0	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.0	0.6	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.2	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.1	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.3	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.0	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0	0.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.5	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.0	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.4	GO:0004348	glucosylceramidase activity(GO:0004348)
0.5	2.0	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.5	1.5	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3	5.5	GO:0008179	adenylate cyclase binding(GO:0008179)
0.3	1.9	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	3.4	GO:0031419	cobalamin binding(GO:0031419)
0.3	0.9	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3	0.8	GO:0070538	oleic acid binding(GO:0070538)
0.2	1.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2	0.9	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	0.7	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	2.2	GO:0051434	BH3 domain binding(GO:0051434)
0.2	1.2	GO:0004630	phospholipase D activity(GO:0004630)
0.2	2.4	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.2	2.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.2	1.2	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2	0.5	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2	4.9	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.9	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	2.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1	0.4	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1	0.4	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1	0.7	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.4	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	0.9	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	0.6	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.6	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.3	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.1	0.7	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1	0.7	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	4.0	GO:0050699	WW domain binding(GO:0050699)
0.1	1.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	1.0	GO:0031386	protein tag(GO:0031386)
0.1	1.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.2	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1	8.5	GO:0001618	virus receptor activity(GO:0001618)
0.1	0.3	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	1.4	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	1.1	GO:0043495	protein anchor(GO:0043495)
0.1	1.4	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.2	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.1	1.2	GO:0017166	vinculin binding(GO:0017166)
0.1	1.1	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	0.3	GO:0070568	guanylyltransferase activity(GO:0070568)
0.1	0.9	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.2	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	1.4	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.4	GO:0045545	syndecan binding(GO:0045545)
0.0	0.3	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.3	GO:0035500	MH2 domain binding(GO:0035500)
0.0	1.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.3	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.4	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.8	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.2	GO:0019828	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.4	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.4	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.3	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.8	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.2	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0	1.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.2	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.1	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.4	GO:0035240	dopamine binding(GO:0035240)
0.0	1.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.0	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	1.0	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	1.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.7	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.3	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0000182	rDNA binding(GO:0000182)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.4	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.0	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.4	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.0	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.3	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	1.4	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.5	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.4	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.6	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.1	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.8	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.4	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	1.2	GO:0019905	syntaxin binding(GO:0019905)
0.0	1.5	GO:0008565	protein transporter activity(GO:0008565)
0.0	2.1	GO:0044325	ion channel binding(GO:0044325)
0.0	0.7	GO:0005507	copper ion binding(GO:0005507)
0.0	0.3	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.7	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0016499	orexin receptor activity(GO:0016499)
0.0	0.1	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	1.6	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.0	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.2	GO:0001968	fibronectin binding(GO:0001968)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:2000276	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4	1.3	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.4	1.8	GO:2000569	T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.3	1.7	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3	1.0	GO:0071344	diphosphate metabolic process(GO:0071344)
0.3	0.8	GO:0032203	telomere formation via telomerase(GO:0032203)
0.3	3.9	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	0.6	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2	0.6	GO:0035854	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2	0.8	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.2	0.5	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.2	0.5	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.2	0.5	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1	0.4	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.1	0.3	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1	0.6	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.3	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1	0.3	GO:0072425	signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.1	0.3	GO:0031627	telomeric loop formation(GO:0031627)
0.1	0.4	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.1	0.8	GO:0035799	ureter maturation(GO:0035799)
0.1	0.3	GO:1900060	glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1	0.2	GO:0048597	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1	0.2	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1	0.6	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	0.4	GO:0033686	oocyte growth(GO:0001555) positive regulation of luteinizing hormone secretion(GO:0033686)
0.1	0.4	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.1	1.0	GO:0015671	oxygen transport(GO:0015671)
0.1	0.3	GO:0072166	posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1	0.9	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1	0.3	GO:0002880	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1	0.7	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.3	GO:0030259	lipid glycosylation(GO:0030259)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1	0.2	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	0.3	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.3	GO:0005997	xylulose metabolic process(GO:0005997)
0.1	0.2	GO:0060152	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1	0.2	GO:1903028	positive regulation of opsonization(GO:1903028)
0.1	0.2	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.2	GO:1903676	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1	0.2	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1	0.2	GO:0060061	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) Spemann organizer formation(GO:0060061)
0.1	0.2	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.1	0.1	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1	0.2	GO:0015808	L-alanine transport(GO:0015808)
0.1	0.3	GO:0048478	replication fork protection(GO:0048478)
0.1	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	0.4	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.1	0.6	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.1	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.1	0.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	1.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.8	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.6	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0	0.4	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0015709	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0	0.3	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.1	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.0	0.1	GO:0052251	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0	0.0	GO:1901535	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0	0.2	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.0	0.3	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.0	0.2	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0	0.3	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.2	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0	0.4	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.3	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.4	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.4	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0	0.2	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	2.0	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0006097	glyoxylate cycle(GO:0006097)
0.0	0.1	GO:0071301	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0	0.3	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0	0.1	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.4	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0	0.1	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.2	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.3	GO:0001865	NK T cell differentiation(GO:0001865)
0.0	0.3	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.0	0.4	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.2	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.1	GO:0070781	response to biotin(GO:0070781)
0.0	0.1	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.2	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.0	0.2	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.3	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.1	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0007113	endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0	0.1	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0	1.3	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.5	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.4	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.0	0.2	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	1.6	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.0	GO:0003220	left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.0	0.1	GO:1903974	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0	0.3	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.7	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.2	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.5	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.3	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.8	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0	1.2	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.2	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0043634	polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0	0.0	GO:0036090	cleavage furrow ingression(GO:0036090)
0.0	0.6	GO:0034724	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0	0.0	GO:0033684	regulation of luteinizing hormone secretion(GO:0033684)
0.0	0.2	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.1	GO:0046013	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.2	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.0	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0090625	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.5	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	1.9	GO:0046330	positive regulation of JNK cascade(GO:0046330)
0.0	0.1	GO:1905225	thyroid-stimulating hormone signaling pathway(GO:0038194) cellular response to glycoprotein(GO:1904588) response to thyrotropin-releasing hormone(GO:1905225) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0	0.2	GO:0060056	mammary gland involution(GO:0060056) self proteolysis(GO:0097264)
0.0	0.0	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.2	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.1	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.0	0.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.3	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.7	GO:0022900	electron transport chain(GO:0022900)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.0	0.2	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.4	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.2	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	0.1	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.4	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.0	GO:0006325	chromatin organization(GO:0006325)
0.0	0.0	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.8	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0090649	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0	0.0	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.2	GO:0032607	interferon-alpha production(GO:0032607)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.1	GO:1990504	dense core granule exocytosis(GO:1990504)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.5	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0	0.3	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0	0.1	GO:0048681	negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	1.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	2.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.9	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.8	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	1.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	PID BMP PATHWAY	BMP receptor signaling
0.0	0.3	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.4	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.7	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.9	PID E2F PATHWAY	E2F transcription factor network

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	2.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	2.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.6	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.7	PID ATM PATHWAY	ATM pathway
0.0	1.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	4.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	5.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.5	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.7	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.6	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	2.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	1.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	1.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	1.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.6	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	1.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	GO:0032591	dendritic spine membrane(GO:0032591)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.0	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	1.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	1.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	2.4	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	1.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.0	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	4.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	2.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.8	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	4.3	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	6.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	2.7	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.9	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	2.1	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.0	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	8.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.9	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	3.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.5	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
1.1	4.3	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.9	2.7	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.8	2.3	GO:0030350	iron-responsive element binding(GO:0030350)
0.7	0.7	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.7	5.1	GO:0016015	morphogen activity(GO:0016015)
0.7	7.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.7	4.7	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.7	2.0	GO:0098626	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.6	3.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.6	1.8	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.6	1.7	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.6	2.8	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.6	2.2	GO:0070051	fibrinogen binding(GO:0070051)
0.5	2.1	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.5	8.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.5	1.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5	1.5	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.5	1.5	GO:0016662	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.5	1.5	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.5	5.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.5	1.9	GO:1904408	dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.5	3.3	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.5	1.4	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.4	1.3	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.4	3.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.4	1.3	GO:0052895	norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.4	2.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4	1.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.4	2.5	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.4	2.5	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.4	1.2	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4	1.2	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4	2.4	GO:0030172	troponin C binding(GO:0030172)
0.4	2.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.4	5.6	GO:0031014	troponin T binding(GO:0031014)
0.4	2.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.4	4.7	GO:0045159	myosin II binding(GO:0045159)
0.4	1.1	GO:0070538	oleic acid binding(GO:0070538)
0.4	3.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.4	1.8	GO:0050436	microfibril binding(GO:0050436)
0.4	1.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.4	2.9	GO:0046923	ER retention sequence binding(GO:0046923)
0.4	2.9	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	0.7	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
0.4	1.8	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.3	1.4	GO:0016361	activin receptor activity, type I(GO:0016361)
0.3	0.7	GO:0005522	profilin binding(GO:0005522)
0.3	7.5	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3	1.0	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.3	1.3	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.3	1.0	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3	5.3	GO:0017166	vinculin binding(GO:0017166)
0.3	1.0	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3	1.3	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3	0.6	GO:0097001	ceramide binding(GO:0097001)
0.3	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3	1.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.3	0.3	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.3	1.2	GO:0031716	calcitonin receptor binding(GO:0031716)
0.3	1.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.3	0.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.3	0.9	GO:0008430	selenium binding(GO:0008430)
0.3	4.8	GO:0017049	GTP-Rho binding(GO:0017049)
0.3	2.1	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	0.9	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.3	0.6	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.3	0.6	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.3	0.9	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.3	0.9	GO:0043237	laminin-1 binding(GO:0043237)
0.3	2.9	GO:0042731	PH domain binding(GO:0042731)
0.3	1.4	GO:0016403	dimethylargininase activity(GO:0016403)
0.3	0.3	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3	7.4	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
0.3	0.8	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.3	27.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.3	1.7	GO:0034235	GPI anchor binding(GO:0034235)
0.3	4.4	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.3	1.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	0.8	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.3	0.8	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.3	0.3	GO:0046848	hydroxyapatite binding(GO:0046848)
0.3	1.6	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.3	1.6	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.3	0.8	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.3	1.3	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.3	2.6	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.3	0.8	GO:0004797	thymidine kinase activity(GO:0004797)
0.3	0.8	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.3	0.8	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
0.3	1.0	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.3	16.1	GO:0045182	translation regulator activity(GO:0045182)
0.3	1.0	GO:0032217	riboflavin transporter activity(GO:0032217)
0.3	0.3	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3	1.3	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3	2.0	GO:0004111	creatine kinase activity(GO:0004111)
0.3	2.8	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.3	2.3	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	1.2	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2	0.7	GO:0017002	activin-activated receptor activity(GO:0017002)
0.2	3.9	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2	5.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	2.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	1.0	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.2	1.0	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2	1.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2	1.0	GO:0004031	aldehyde oxidase activity(GO:0004031)
0.2	5.0	GO:0001968	fibronectin binding(GO:0001968)
0.2	0.2	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.2	1.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.2	0.7	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.2	1.6	GO:0070573	metallodipeptidase activity(GO:0070573)
0.2	2.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	0.7	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2	0.4	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2	2.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2	1.3	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.2	0.7	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2	0.7	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2	1.5	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.2	11.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	0.9	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.2	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.2	4.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.2	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.2	1.2	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2	1.2	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.2	0.4	GO:0098821	BMP receptor activity(GO:0098821)
0.2	0.2	GO:0042805	actinin binding(GO:0042805)
0.2	2.0	GO:0070410	co-SMAD binding(GO:0070410)
0.2	1.0	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.2	0.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.2	3.2	GO:0043495	protein anchor(GO:0043495)
0.2	0.8	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2	2.8	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2	0.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.2	0.8	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2	0.6	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2	1.0	GO:0015639	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2	1.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	0.8	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2	4.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.2	1.9	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	3.7	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2	0.2	GO:0019239	deaminase activity(GO:0019239)
0.2	4.1	GO:0008483	transaminase activity(GO:0008483)
0.2	0.7	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	0.4	GO:0031489	myosin V binding(GO:0031489)
0.2	0.6	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2	1.9	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	0.6	GO:0036080	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2	0.6	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.2	0.2	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.2	0.6	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2	0.5	GO:0017018	myosin phosphatase activity(GO:0017018)
0.2	1.6	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.2	1.1	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.2	0.9	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.2	0.7	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2	4.8	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2	0.9	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2	0.5	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2	0.9	GO:0045118	azole transporter activity(GO:0045118)
0.2	0.7	GO:0061714	folic acid receptor activity(GO:0061714)
0.2	0.5	GO:0036122	BMP binding(GO:0036122)
0.2	0.9	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2	0.5	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.2	14.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	2.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2	9.1	GO:0005158	insulin receptor binding(GO:0005158)
0.2	9.7	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2	0.8	GO:0008420	CTD phosphatase activity(GO:0008420)
0.2	0.3	GO:0031386	protein tag(GO:0031386)
0.2	1.0	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.2	1.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.2	0.5	GO:0004962	endothelin receptor activity(GO:0004962)
0.2	0.3	GO:0008252	nucleotidase activity(GO:0008252)
0.2	1.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.2	0.8	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.2	0.6	GO:0071253	connexin binding(GO:0071253)
0.2	2.5	GO:0031005	filamin binding(GO:0031005)
0.2	0.2	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.2	0.6	GO:0019770	IgG receptor activity(GO:0019770)
0.2	0.6	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.2	0.3	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2	0.2	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2	25.9	GO:0008201	heparin binding(GO:0008201)
0.2	1.2	GO:0004954	prostanoid receptor activity(GO:0004954)
0.2	0.8	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2	1.8	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.2	0.5	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2	0.8	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.2	2.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.2	0.3	GO:0008384	IkappaB kinase activity(GO:0008384)
0.2	0.5	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.2	0.5	GO:0008941	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.2	1.1	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	3.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.6	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	1.6	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	1.2	GO:0046870	cadmium ion binding(GO:0046870)
0.1	1.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.9	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	0.6	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.1	2.5	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.6	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.7	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	0.4	GO:0004104	cholinesterase activity(GO:0004104)
0.1	0.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.1	GO:0042923	neuropeptide binding(GO:0042923)
0.1	0.6	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.4	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.6	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	2.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.7	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1	2.1	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.7	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	0.4	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	1.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	0.1	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	0.4	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.1	3.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	0.5	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	1.3	GO:0044548	S100 protein binding(GO:0044548)
0.1	1.9	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.4	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1	0.7	GO:0000182	rDNA binding(GO:0000182)
0.1	1.7	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	3.0	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.5	GO:0004348	glucosylceramidase activity(GO:0004348)
0.1	0.9	GO:1990226	histone methyltransferase binding(GO:1990226)
0.1	0.4	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.1	1.0	GO:0005497	androgen binding(GO:0005497)
0.1	0.9	GO:0050815	phosphoserine binding(GO:0050815)
0.1	4.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.3	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1	1.0	GO:0048495	Roundabout binding(GO:0048495)
0.1	1.7	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.5	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.1	0.5	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1	0.4	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.3	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	0.8	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.4	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1	0.6	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.1	0.6	GO:0003777	microtubule motor activity(GO:0003777)
0.1	0.3	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.1	2.5	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	0.5	GO:0048185	activin binding(GO:0048185)
0.1	0.8	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1	5.3	GO:0005518	collagen binding(GO:0005518)
0.1	0.5	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.1	0.5	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	6.7	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	2.8	GO:0003924	GTPase activity(GO:0003924)
0.1	0.7	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	0.1	GO:0008238	exopeptidase activity(GO:0008238)
0.1	1.0	GO:0051287	NAD binding(GO:0051287)
0.1	0.4	GO:0071209	U7 snRNA binding(GO:0071209)
0.1	0.7	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.2	GO:0030375	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.4	GO:0019961	interferon binding(GO:0019961)
0.1	0.2	GO:0017089	glycolipid transporter activity(GO:0017089)
0.1	1.3	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.5	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.2	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	0.5	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.6	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	2.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	1.4	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.1	0.3	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.1	0.3	GO:0019107	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1	0.9	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	0.1	GO:0033149	FFAT motif binding(GO:0033149)
0.1	0.1	GO:0042806	fucose binding(GO:0042806)
0.1	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.4	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.1	0.7	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	1.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.4	GO:0047708	biotinidase activity(GO:0047708)
0.1	2.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.7	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1	0.4	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1	0.5	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	1.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.7	GO:0048039	ubiquinone binding(GO:0048039)
0.1	0.4	GO:0003774	motor activity(GO:0003774)
0.1	1.6	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.3	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	0.8	GO:0031369	translation initiation factor binding(GO:0031369)
0.1	0.6	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.1	0.4	GO:0034452	dynactin binding(GO:0034452)
0.1	0.4	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.8	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.3	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1	0.5	GO:0008097	5S rRNA binding(GO:0008097)
0.1	0.4	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	1.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.5	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.1	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.1	0.9	GO:0048038	quinone binding(GO:0048038)
0.1	0.4	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	1.4	GO:0048156	tau protein binding(GO:0048156)
0.1	1.0	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	0.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1	0.9	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.3	GO:0070984	SET domain binding(GO:0070984)
0.1	0.3	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	0.5	GO:0004882	androgen receptor activity(GO:0004882)
0.1	0.5	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.1	2.3	GO:0017048	Rho GTPase binding(GO:0017048)
0.1	1.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	1.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	2.0	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.1	0.5	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.1	0.6	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	0.4	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	3.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.3	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.1	10.5	GO:0005178	integrin binding(GO:0005178)
0.1	1.8	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.3	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	1.3	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
0.1	0.9	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.4	GO:0019862	IgA binding(GO:0019862)
0.1	3.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	4.1	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1	0.6	GO:0044594	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1	4.0	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	7.3	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	1.6	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.1	0.3	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	0.6	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1	0.7	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	3.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.2	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	0.3	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.1	0.8	GO:0019894	kinesin binding(GO:0019894)
0.1	0.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.4	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.1	0.6	GO:1990459	transferrin receptor binding(GO:1990459)
0.1	0.4	GO:0002046	opsin binding(GO:0002046)
0.1	0.2	GO:0008276	protein methyltransferase activity(GO:0008276)
0.1	1.2	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1	2.4	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.3	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1	0.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.3	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.1	1.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.8	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1	0.3	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1	0.2	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.1	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.4	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.7	GO:0035877	death effector domain binding(GO:0035877)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.6	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.2	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1	0.9	GO:0000150	recombinase activity(GO:0000150)
0.1	0.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.4	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.2	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.1	0.1	GO:0034618	arginine binding(GO:0034618)
0.1	0.3	GO:0004966	galanin receptor activity(GO:0004966)
0.1	3.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	0.6	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	1.8	GO:0042166	acetylcholine binding(GO:0042166)
0.1	0.2	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	0.5	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1	0.1	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.1	0.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.1	0.2	GO:0016936	galactoside binding(GO:0016936)
0.1	6.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.5	GO:0004532	exoribonuclease activity(GO:0004532)
0.1	0.7	GO:0032357	oxidized purine DNA binding(GO:0032357)
0.1	0.3	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.2	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.1	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1	1.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.7	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.2	GO:0000035	acyl binding(GO:0000035)
0.1	0.2	GO:0052870	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1	1.4	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	0.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.7	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1	0.1	GO:0050733	RS domain binding(GO:0050733)
0.1	1.0	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.3	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.4	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.2	GO:0033592	RNA strand annealing activity(GO:0033592)
0.1	1.0	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.4	GO:0035174	histone serine kinase activity(GO:0035174)
0.1	0.2	GO:0035500	MH2 domain binding(GO:0035500)
0.1	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.1	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.1	0.6	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	1.4	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	0.1	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
0.1	1.0	GO:0009881	photoreceptor activity(GO:0009881)
0.1	0.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.1	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.1	0.3	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1	0.1	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.1	0.2	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.1	1.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.3	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	1.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.6	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.2	GO:0046527	glucosyltransferase activity(GO:0046527)
0.1	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.6	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.1	GO:0070905	serine binding(GO:0070905)
0.1	0.5	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1	0.6	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.2	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.6	GO:0015266	protein channel activity(GO:0015266)
0.1	0.3	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.1	0.5	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.2	GO:0004074	biliverdin reductase activity(GO:0004074)
0.1	0.5	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1	1.6	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.1	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	0.1	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.1	1.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.5	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	0.3	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.1	0.7	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	0.4	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.9	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.2	GO:0036317	tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1	0.2	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.1	0.7	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	1.4	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.3	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	2.2	GO:0017022	myosin binding(GO:0017022)
0.1	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.1	GO:1990763	arrestin family protein binding(GO:1990763)
0.1	0.1	GO:0017016	Ras GTPase binding(GO:0017016)
0.1	0.1	GO:0000827	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	0.2	GO:0043426	MRF binding(GO:0043426)
0.1	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.2	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.1	0.2	GO:0043178	alcohol binding(GO:0043178)
0.1	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.4	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.1	0.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.6	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.1	GO:0051213	dioxygenase activity(GO:0051213)
0.1	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.4	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.5	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.2	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	2.1	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	1.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.1	1.0	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0	0.2	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.2	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.3	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.0	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.4	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.3	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0004132	dCMP deaminase activity(GO:0004132)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.5	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.0	0.3	GO:0001848	complement binding(GO:0001848)
0.0	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.2	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	1.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0001861	complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0	0.0	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.9	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0032089	NACHT domain binding(GO:0032089)
0.0	0.2	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.4	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0015235	cobalamin transporter activity(GO:0015235)
0.0	0.3	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	1.0	GO:0030553	cGMP binding(GO:0030553)
0.0	0.7	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	1.2	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.5	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.4	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.1	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.3	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.1	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.0	0.6	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.2	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.0	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.0	0.1	GO:0030366	molybdopterin synthase activity(GO:0030366)
0.0	0.4	GO:0016208	AMP binding(GO:0016208)
0.0	0.2	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.0	GO:0005119	smoothened binding(GO:0005119)
0.0	1.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	5.1	GO:0044325	ion channel binding(GO:0044325)
0.0	0.5	GO:0019841	retinol binding(GO:0019841)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0032135	DNA insertion or deletion binding(GO:0032135) single base insertion or deletion binding(GO:0032138)
0.0	1.0	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0	0.6	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.1	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.9	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.5	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.7	GO:0030551	cyclic nucleotide binding(GO:0030551)
0.0	0.1	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.0	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.4	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.4	GO:0015929	hexosaminidase activity(GO:0015929)
0.0	0.1	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.0	1.1	GO:0004180	carboxypeptidase activity(GO:0004180)
0.0	0.3	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	1.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	1.5	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.1	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.0	0.1	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0	0.9	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:1903135	cupric ion binding(GO:1903135)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	1.7	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0	2.2	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.0	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.0	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0098631	protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0	0.2	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.0	0.3	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.0	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0005372	water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.0	0.0	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.4	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.7	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.0	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.0	0.0	GO:0004368	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	10.3	GO:0005525	GTP binding(GO:0005525)
0.0	1.4	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.0	0.3	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.1	GO:0070697	activin receptor binding(GO:0070697)
0.0	0.1	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	2.0	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.0	0.4	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.1	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.4	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	1.0	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0004386	helicase activity(GO:0004386)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	2.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.3	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0070990	snRNP binding(GO:0070990)
0.0	0.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.0	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:1902122	chenodeoxycholic acid binding(GO:1902122)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0004730	pseudouridylate synthase activity(GO:0004730)
0.0	0.0	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.5	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0004766	spermidine synthase activity(GO:0004766)
0.0	0.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	1.1	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.3	GO:0071949	FAD binding(GO:0071949)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0052840	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0	0.1	GO:0015265	urea channel activity(GO:0015265)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	2.4	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	1.7	GO:0020037	heme binding(GO:0020037)
0.0	0.0	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.0	0.1	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.0	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
0.0	0.0	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.0	0.1	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0	1.3	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0019825	oxygen binding(GO:0019825)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.1	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.0	GO:0016429	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0	0.0	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	0.1	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.2	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0008135	translation factor activity, RNA binding(GO:0008135)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.0	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.1	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0	0.0	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0004743	pyruvate kinase activity(GO:0004743)
0.0	0.1	GO:0016684	peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0	0.0	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.0	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	0.2	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0005501	retinoic acid binding(GO:0001972) retinoid binding(GO:0005501)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.0	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.1	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.0	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	0.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.0	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.4	GO:0005044	scavenger receptor activity(GO:0005044)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	1.6	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.2	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.8	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	1.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	1.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	1.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	1.2	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	2.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	2.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	10.2	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
2.1	8.3	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
1.5	8.8	GO:0030421	defecation(GO:0030421)
1.3	5.2	GO:0071492	cellular response to UV-A(GO:0071492)
1.2	3.7	GO:1902303	negative regulation of potassium ion export(GO:1902303)
1.1	3.3	GO:0061386	closure of optic fissure(GO:0061386)
1.0	8.6	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.8	2.5	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.7	2.1	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.7	2.0	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.6	2.6	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.6	1.9	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.6	11.4	GO:0007021	tubulin complex assembly(GO:0007021)
0.6	1.9	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6	11.3	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.6	3.7	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.6	1.8	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6	2.3	GO:1902361	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.6	4.0	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.6	2.8	GO:0090131	mesenchyme migration(GO:0090131)
0.6	10.6	GO:0070208	protein heterotrimerization(GO:0070208)
0.5	1.6	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.5	2.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.5	2.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.5	1.5	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.5	1.5	GO:0090427	activation of meiosis(GO:0090427)
0.5	1.4	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.5	1.4	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.5	1.4	GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.5	5.1	GO:0033227	dsRNA transport(GO:0033227)
0.5	2.3	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.4	1.8	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.4	0.9	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.4	0.9	GO:0060374	mast cell differentiation(GO:0060374)
0.4	1.3	GO:0061760	antifungal innate immune response(GO:0061760)
0.4	1.6	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.4	1.2	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.4	4.0	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.4	1.2	GO:0090298	negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.4	1.2	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.4	3.2	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4	1.2	GO:1901899	positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.4	1.2	GO:0060844	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4	1.5	GO:0072299	posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.4	1.1	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4	0.8	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.4	5.7	GO:0098711	iron ion import into cell(GO:0097459) iron ion import across plasma membrane(GO:0098711)
0.4	1.5	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.4	1.9	GO:0010587	miRNA catabolic process(GO:0010587)
0.4	1.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.4	4.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.4	1.1	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4	1.5	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.4	2.9	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.4	1.1	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.4	2.8	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.3	2.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3	1.0	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3	1.4	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.3	1.4	GO:0048371	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.3	1.4	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.3	1.0	GO:0072276	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3	2.0	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.3	0.7	GO:0032486	Rap protein signal transduction(GO:0032486)
0.3	1.0	GO:0071529	cementum mineralization(GO:0071529)
0.3	0.7	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3	1.0	GO:0009447	putrescine catabolic process(GO:0009447)
0.3	0.7	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.3	1.0	GO:0060578	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3	1.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.3	1.9	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.3	1.9	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.3	0.9	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.3	0.9	GO:1904617	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.3	1.8	GO:0009082	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.3	0.9	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.3	0.9	GO:0032900	negative regulation of neurotrophin production(GO:0032900)
0.3	1.4	GO:2000035	regulation of stem cell division(GO:2000035)
0.3	0.3	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.3	0.9	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.3	1.7	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.3	2.8	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.3	0.8	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.3	3.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.3	0.8	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3	1.4	GO:0035377	transepithelial water transport(GO:0035377)
0.3	3.1	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3	1.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.3	1.4	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3	2.4	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.3	1.3	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3	2.9	GO:0034465	response to carbon monoxide(GO:0034465)
0.3	0.8	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3	0.8	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.3	0.3	GO:0055096	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3	4.2	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2	0.7	GO:0003408	optic cup formation involved in camera-type eye development(GO:0003408)
0.2	1.0	GO:0019086	late viral transcription(GO:0019086)
0.2	1.2	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.2	1.0	GO:0051458	corticotropin secretion(GO:0051458)
0.2	1.4	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.2	1.0	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.2	0.7	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.2	0.5	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.2	1.2	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.2	1.6	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.2	0.7	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2	1.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.2	0.7	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.2	5.6	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.2	2.5	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2	0.9	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2	0.7	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2	2.2	GO:0032264	IMP salvage(GO:0032264)
0.2	0.7	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2	1.1	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.2	0.9	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2	0.7	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.2	0.9	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.2	2.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.2	2.2	GO:0010265	SCF complex assembly(GO:0010265)
0.2	0.6	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2	1.3	GO:0071317	cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.2	3.4	GO:0006527	arginine catabolic process(GO:0006527)
0.2	5.0	GO:0006337	nucleosome disassembly(GO:0006337)
0.2	1.5	GO:0007256	activation of JNKK activity(GO:0007256)
0.2	0.6	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.2	0.6	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.2	0.8	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2	0.8	GO:0070982	L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.2	0.8	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.2	1.6	GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.2	1.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2	3.0	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.2	0.4	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.2	0.4	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2	1.4	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2	1.8	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.2	1.0	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.2	0.8	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.2	1.0	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.2	0.8	GO:0042414	epinephrine metabolic process(GO:0042414)
0.2	1.0	GO:1903974	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.2	1.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.2	0.6	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.2	1.9	GO:0046325	negative regulation of glucose import(GO:0046325)
0.2	0.8	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.2	0.8	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2	1.1	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.2	0.6	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2	0.6	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2	1.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.2	0.9	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.2	1.5	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2	0.4	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2	0.9	GO:1903412	response to bile acid(GO:1903412)
0.2	0.2	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.2	0.7	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.2	0.9	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2	1.3	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.2	0.7	GO:0048749	compound eye development(GO:0048749)
0.2	0.5	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2	0.9	GO:0043696	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2	0.5	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.2	0.2	GO:0090270	fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.2	2.7	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.2	0.2	GO:0006110	regulation of glycolytic process(GO:0006110)
0.2	6.5	GO:0006376	mRNA splice site selection(GO:0006376)
0.2	1.2	GO:0050915	sensory perception of sour taste(GO:0050915)
0.2	0.7	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.2	4.9	GO:0043968	histone H2A acetylation(GO:0043968)
0.2	0.8	GO:0086047	membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2	0.8	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2	0.7	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.2	1.3	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.2	0.5	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.2	0.7	GO:0000103	sulfate assimilation(GO:0000103)
0.2	0.5	GO:1904899	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2	0.7	GO:0060613	fat pad development(GO:0060613)
0.2	0.5	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2	0.7	GO:2000672	regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.2	0.5	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.2	0.2	GO:0045351	interferon-alpha biosynthetic process(GO:0045349) interferon-beta biosynthetic process(GO:0045350) type I interferon biosynthetic process(GO:0045351) regulation of interferon-alpha biosynthetic process(GO:0045354) regulation of interferon-beta biosynthetic process(GO:0045357)
0.2	1.8	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2	0.8	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2	2.1	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.2	0.3	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.2	1.0	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.2	0.6	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.2	0.2	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.2	0.6	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.2	0.2	GO:2001028	positive regulation of endothelial cell chemotaxis(GO:2001028)
0.2	1.4	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.2	0.5	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2	0.8	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.2	0.5	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.2	0.6	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.2	0.3	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.2	0.5	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.6	GO:0021897	forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1	0.3	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	1.8	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.4	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1	0.3	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.1	0.9	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1	0.4	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	1.9	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	0.9	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	1.1	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.9	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	0.7	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.1	0.3	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	0.1	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1	1.0	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	1.2	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.1	1.4	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	0.8	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.1	1.0	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1	0.7	GO:1901906	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1	0.3	GO:0044320	cellular response to leptin stimulus(GO:0044320)
0.1	0.1	GO:0007296	cytoplasm organization(GO:0007028) vitellogenesis(GO:0007296)
0.1	0.4	GO:0002265	astrocyte activation involved in immune response(GO:0002265)
0.1	1.0	GO:0006226	dUMP biosynthetic process(GO:0006226)
0.1	0.1	GO:0061032	visceral serous pericardium development(GO:0061032)
0.1	0.7	GO:0015862	uridine transport(GO:0015862)
0.1	0.7	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.4	GO:1902528	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1	1.5	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.1	GO:0012502	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1	0.3	GO:0021569	rhombomere 3 development(GO:0021569)
0.1	0.4	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1	1.1	GO:0070344	fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345)
0.1	0.4	GO:0031587	detection of endogenous stimulus(GO:0009726) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1	0.1	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1	0.4	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.4	GO:0046449	creatinine metabolic process(GO:0046449)
0.1	0.3	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.1	0.4	GO:0007518	myoblast fate determination(GO:0007518)
0.1	0.5	GO:0009224	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.9	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.3	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.1	0.9	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.1	0.5	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1	0.3	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.1	0.4	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.1	0.8	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.4	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.4	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.1	0.1	GO:0051885	positive regulation of anagen(GO:0051885)
0.1	1.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	0.2	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1	0.7	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	1.5	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.1	0.2	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	0.9	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.4	GO:0006404	RNA import into nucleus(GO:0006404)
0.1	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.6	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	0.4	GO:0061743	motor learning(GO:0061743)
0.1	0.5	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1	1.5	GO:0015671	oxygen transport(GO:0015671)
0.1	1.4	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.6	GO:1902904	clathrin coat disassembly(GO:0072318) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.5	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.5	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1	0.2	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	1.6	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.1	0.7	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.1	0.8	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	1.6	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.1	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.1	0.5	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1	0.5	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.1	0.2	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1	0.9	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.4	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1	0.2	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1	0.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	1.2	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	1.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.2	GO:0097212	lysosomal membrane organization(GO:0097212)
0.1	0.6	GO:0016926	protein desumoylation(GO:0016926)
0.1	0.5	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.1	1.3	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	1.0	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.1	0.1	GO:0061074	regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.1	0.6	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.1	0.3	GO:0097477	spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1	0.4	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.1	0.9	GO:0030091	protein repair(GO:0030091)
0.1	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.3	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.1	0.1	GO:0051582	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.2	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.1	0.2	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.1	2.6	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.1	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1	0.1	GO:2000542	negative regulation of cell fate specification(GO:0009996) negative regulation of gastrulation(GO:2000542)
0.1	1.0	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.1	1.2	GO:0046051	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1	0.8	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.1	0.4	GO:2001171	positive regulation of ATP biosynthetic process(GO:2001171)
0.1	1.8	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1	0.3	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1	0.7	GO:1902047	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.1	0.8	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.7	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.1	6.6	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	0.4	GO:0035811	negative regulation of urine volume(GO:0035811)
0.1	0.6	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
0.1	0.5	GO:0006041	glucosamine metabolic process(GO:0006041)
0.1	0.1	GO:0040031	snRNA modification(GO:0040031)
0.1	0.1	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
0.1	0.3	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.1	0.3	GO:0003190	atrioventricular valve formation(GO:0003190)
0.1	0.8	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.1	GO:1905005	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.1	0.2	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.1	0.6	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.1	0.1	GO:2000078	glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.1	0.5	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.4	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1	1.4	GO:0032060	bleb assembly(GO:0032060)
0.1	0.4	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
0.1	0.3	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.1	0.3	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1	0.4	GO:0036302	atrioventricular canal development(GO:0036302)
0.1	0.2	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.1	0.7	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.1	GO:0051660	establishment of centrosome localization(GO:0051660)
0.1	0.1	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.1	0.9	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1	0.2	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133) nephrogenic mesenchyme morphogenesis(GO:0072134)
0.1	0.7	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.5	GO:0043316	cytotoxic T cell degranulation(GO:0043316)
0.1	0.4	GO:0042473	outer ear morphogenesis(GO:0042473)
0.1	0.3	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	0.4	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1	0.6	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.3	GO:0006172	ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.2	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1	0.1	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1	0.6	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.1	0.3	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	0.7	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	1.1	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.2	GO:0015886	heme transport(GO:0015886)
0.1	0.3	GO:0031291	Ran protein signal transduction(GO:0031291)
0.1	1.1	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1	0.3	GO:1904528	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1	0.9	GO:0030157	pancreatic juice secretion(GO:0030157)
0.1	0.6	GO:0008218	bioluminescence(GO:0008218)
0.1	1.8	GO:0006825	copper ion transport(GO:0006825)
0.1	0.3	GO:0052553	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1	0.3	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.1	0.1	GO:0021769	orbitofrontal cortex development(GO:0021769)
0.1	1.2	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.2	GO:0035822	gene conversion(GO:0035822)
0.1	1.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	0.4	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.6	GO:0021936	regulation of cerebellar granule cell precursor proliferation(GO:0021936)
0.1	0.6	GO:0051601	exocyst localization(GO:0051601)
0.1	0.4	GO:0021759	globus pallidus development(GO:0021759)
0.1	0.3	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1	0.2	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1	0.2	GO:0048664	neuron fate determination(GO:0048664)
0.1	0.4	GO:1901660	calcium ion export(GO:1901660)
0.1	0.3	GO:0036343	psychomotor behavior(GO:0036343)
0.1	0.2	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.3	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	0.2	GO:0035739	CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
0.1	0.2	GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1	0.8	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.1	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
0.1	0.1	GO:0034091	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.1	0.3	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.1	0.2	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1	0.3	GO:0071373	cellular response to luteinizing hormone stimulus(GO:0071373)
0.1	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.1	0.2	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.1	0.6	GO:0007379	segment specification(GO:0007379)
0.1	0.2	GO:0090235	regulation of metaphase plate congression(GO:0090235)
0.1	0.4	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.5	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.1	0.2	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	0.4	GO:0060536	cartilage morphogenesis(GO:0060536)
0.1	0.3	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	3.6	GO:0008542	visual learning(GO:0008542)
0.1	0.1	GO:0030823	regulation of cGMP metabolic process(GO:0030823)
0.1	0.2	GO:1990108	protein linear deubiquitination(GO:1990108)
0.1	0.1	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1	0.4	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.1	0.2	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	0.9	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.1	0.5	GO:0072718	response to cisplatin(GO:0072718)
0.1	1.3	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.1	0.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.8	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1	0.7	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.4	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	0.3	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.1	0.2	GO:0070781	response to biotin(GO:0070781)
0.1	0.5	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.3	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	1.8	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.1	0.1	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1	1.0	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	0.4	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.1	1.2	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	0.3	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.1	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	1.0	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	1.4	GO:0003416	endochondral bone growth(GO:0003416)
0.1	0.4	GO:0070827	chromatin maintenance(GO:0070827)
0.1	1.4	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.1	0.2	GO:0010390	histone monoubiquitination(GO:0010390)
0.1	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	1.0	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
0.1	0.5	GO:0060897	neural plate regionalization(GO:0060897)
0.1	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1	0.2	GO:0006524	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.1	3.0	GO:0061718	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1	0.7	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.1	0.1	GO:0002644	negative regulation of tolerance induction(GO:0002644)
0.1	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.6	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.2	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.7	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.3	GO:0035865	cellular response to potassium ion(GO:0035865)
0.1	0.3	GO:0070375	ERK5 cascade(GO:0070375)
0.1	0.2	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.1	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1	0.1	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.1	0.2	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	0.4	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.3	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	2.5	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.1	GO:0019230	proprioception(GO:0019230)
0.1	1.0	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.3	GO:0048478	replication fork protection(GO:0048478)
0.1	0.3	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1	0.1	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1	0.1	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.1	0.6	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	0.3	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	0.3	GO:1990785	response to water-immersion restraint stress(GO:1990785)
0.1	0.4	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1	0.3	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.6	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.1	0.8	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1	0.7	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1	0.9	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.1	0.3	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.1	0.5	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1	0.5	GO:0051451	myoblast migration(GO:0051451)
0.1	0.6	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.1	0.2	GO:0097167	circadian regulation of translation(GO:0097167)
0.1	0.2	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.1	1.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.2	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.1	0.7	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	2.1	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.4	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.2	GO:2000197	regulation of ribonucleoprotein complex localization(GO:2000197)
0.1	0.7	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.1	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	0.7	GO:0090128	regulation of synapse maturation(GO:0090128)
0.1	0.2	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.1	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1	0.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.1	0.1	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.1	0.2	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.8	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1	0.9	GO:0008340	determination of adult lifespan(GO:0008340)
0.1	0.3	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.1	0.1	GO:0015965	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1	0.3	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.1	0.2	GO:0007440	foregut morphogenesis(GO:0007440)
0.1	0.3	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.1	0.2	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.1	0.6	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.8	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.3	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.2	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.1	1.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1	0.2	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.2	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	0.3	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.4	GO:0016556	mRNA modification(GO:0016556)
0.1	1.0	GO:0072539	T-helper 17 cell differentiation(GO:0072539)
0.1	0.5	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.1	GO:0033184	positive regulation of histone ubiquitination(GO:0033184) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1	0.1	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.1	0.2	GO:0044539	long-chain fatty acid import(GO:0044539)
0.1	0.5	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.1	0.2	GO:0060019	radial glial cell differentiation(GO:0060019)
0.1	0.1	GO:0051414	response to cortisol(GO:0051414)
0.1	0.3	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	0.4	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.1	0.4	GO:0014854	response to inactivity(GO:0014854)
0.1	0.4	GO:0097398	response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1	0.4	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.1	3.5	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	0.4	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	1.1	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1	0.3	GO:1901093	regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1	4.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.3	GO:0001554	luteolysis(GO:0001554)
0.1	0.8	GO:0048266	behavioral response to pain(GO:0048266)
0.1	3.8	GO:0006968	cellular defense response(GO:0006968)
0.1	0.5	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:0000967	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1	0.4	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	0.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.1	0.3	GO:0009247	glycolipid biosynthetic process(GO:0009247)
0.1	0.1	GO:0072697	protein localization to cell cortex(GO:0072697)
0.1	0.4	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	1.0	GO:0006625	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1	0.2	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	2.3	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.4	GO:0097106	postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107)
0.0	0.9	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0	1.7	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.4	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.5	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.4	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.2	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0	0.6	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.0	0.1	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.0	0.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.0	0.1	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0	0.3	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.4	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.0	GO:0038001	paracrine signaling(GO:0038001)
0.0	1.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.5	GO:1990845	adaptive thermogenesis(GO:1990845)
0.0	0.8	GO:1903392	negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0051685	maintenance of ER location(GO:0051685)
0.0	0.1	GO:1904044	response to aldosterone(GO:1904044)
0.0	0.3	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.3	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.2	GO:0048669	collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696) negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0	0.3	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.8	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.2	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.0	2.1	GO:0065002	intracellular protein transmembrane transport(GO:0065002)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292)
0.0	0.0	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.0	0.7	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	3.0	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.1	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0	0.6	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.0	0.1	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.0	0.1	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0	0.1	GO:0034398	telomere tethering at nuclear periphery(GO:0034398)
0.0	1.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.2	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.2	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.2	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.2	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0	0.5	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	1.0	GO:0007131	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.3	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.9	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	1.0	GO:0050779	RNA destabilization(GO:0050779)
0.0	1.0	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.3	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.2	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.5	GO:0042023	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0035617	stress granule disassembly(GO:0035617)
0.0	0.5	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.2	GO:0048255	mRNA stabilization(GO:0048255)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.0	0.2	GO:0042631	cellular response to water deprivation(GO:0042631)
0.0	1.3	GO:0043486	histone exchange(GO:0043486)
0.0	0.2	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.0	0.6	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.0	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.2	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.3	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	1.0	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.4	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	1.0	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.4	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.2	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.6	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.8	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.0	0.3	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.5	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.1	GO:1900125	regulation of hyaluronan biosynthetic process(GO:1900125)
0.0	0.3	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	0.9	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	1.3	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.1	GO:1900154	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0	0.1	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.4	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.7	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	1.0	GO:0015695	organic cation transport(GO:0015695)
0.0	0.2	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.1	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	1.4	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.1	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.0	0.4	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.2	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.1	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0	0.0	GO:0014009	glial cell proliferation(GO:0014009)
0.0	0.2	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.4	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.3	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.2	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0070666	regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.0	0.6	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.4	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.3	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.1	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.0	0.0	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0	0.1	GO:0009956	radial pattern formation(GO:0009956)
0.0	0.6	GO:0070932	histone H3 deacetylation(GO:0070932)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0042533	tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.0	0.1	GO:1904779	regulation of protein localization to centrosome(GO:1904779)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.2	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.2	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.3	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.0	0.0	GO:0051935	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0	0.2	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.4	GO:0000022	mitotic spindle elongation(GO:0000022)
0.0	0.1	GO:0071313	cellular response to caffeine(GO:0071313)
0.0	0.1	GO:0072107	ureteric bud formation(GO:0060676) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) mesonephric tubule formation(GO:0072172)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.1	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.7	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.0	0.3	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.3	GO:0030815	negative regulation of cAMP metabolic process(GO:0030815)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.6	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.3	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.6	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.4	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.6	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.2	GO:0038092	nodal signaling pathway(GO:0038092)
0.0	0.4	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.0	0.1	GO:0060424	foregut regionalization(GO:0060423) lung field specification(GO:0060424) primary lung bud formation(GO:0060431) lung induction(GO:0060492)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.0	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.5	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0021592	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.0	0.0	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.1	GO:0006014	D-ribose metabolic process(GO:0006014)
0.0	3.7	GO:0009408	response to heat(GO:0009408)
0.0	0.8	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.2	GO:0090307	mitotic spindle assembly(GO:0090307)
0.0	0.2	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.1	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.0	0.1	GO:1902949	positive regulation of tau-protein kinase activity(GO:1902949)
0.0	0.1	GO:0002522	leukocyte migration involved in immune response(GO:0002522)
0.0	0.1	GO:0030070	insulin processing(GO:0030070)
0.0	0.0	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.0	0.3	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.2	GO:0014029	neural crest formation(GO:0014029)
0.0	0.7	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.2	GO:0097319	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0	0.2	GO:0071173	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.1	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.0	3.0	GO:0015992	proton transport(GO:0015992)
0.0	0.2	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0	0.5	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.0	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
0.0	0.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253) proteasome regulatory particle assembly(GO:0070682)
0.0	0.5	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.4	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.2	GO:0071709	membrane assembly(GO:0071709)
0.0	0.2	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0051446	positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.1	GO:0021534	cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0	0.2	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.2	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.8	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.3	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.3	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.2	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.0	GO:0050666	regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0	0.1	GO:0039526	suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.0	0.2	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.2	GO:0090520	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.5	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:0035963	cellular response to interleukin-13(GO:0035963)
0.0	0.0	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.3	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.3	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.0	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.0	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.0	GO:0071609	chemokine (C-C motif) ligand 5 production(GO:0071609)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0042695	thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:0001694	histamine biosynthetic process(GO:0001694)
0.0	0.1	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.0	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.0	0.5	GO:0006413	translational initiation(GO:0006413)
0.0	0.1	GO:0045006	DNA deamination(GO:0045006)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.5	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0	0.1	GO:0042756	drinking behavior(GO:0042756)
0.0	0.1	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.0	0.4	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:1901160	primary amino compound metabolic process(GO:1901160)
0.0	0.1	GO:0019417	sulfur oxidation(GO:0019417)
0.0	0.0	GO:0051349	positive regulation of lyase activity(GO:0051349)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.0	GO:0030575	nuclear body organization(GO:0030575) nuclear speck organization(GO:0035063)
0.0	0.2	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:0046349	UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0	0.5	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0	0.3	GO:0006826	iron ion transport(GO:0006826)
0.0	0.1	GO:0098838	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.1	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0010934	macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.4	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0071910	determination of pancreatic left/right asymmetry(GO:0035469) determination of digestive tract left/right asymmetry(GO:0071907) determination of liver left/right asymmetry(GO:0071910)
0.0	0.3	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.2	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.2	GO:0007588	excretion(GO:0007588)
0.0	1.8	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.3	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.2	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.0	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0060168	regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0	0.0	GO:1901894	regulation of calcium-transporting ATPase activity(GO:1901894) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.0	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.0	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0	0.1	GO:1904647	response to rotenone(GO:1904647)
0.0	0.1	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.0	GO:0090650	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0	0.1	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
0.0	0.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.1	GO:0045760	positive regulation of action potential(GO:0045760)
0.0	0.1	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0044805	late nucleophagy(GO:0044805)
0.0	0.7	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0	0.1	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.2	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.0	0.1	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.0	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.1	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904) membrane docking(GO:0022406)
0.0	0.3	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.0	GO:0072071	mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0	0.0	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.3	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.0	GO:1904783	positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0	0.1	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0046208	spermine catabolic process(GO:0046208)
0.0	1.2	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.2	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.2	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.0	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.3	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.4	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0	0.0	GO:1990418	response to insulin-like growth factor stimulus(GO:1990418)
0.0	0.1	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.0	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.2	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.0	GO:0018317	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.0	GO:2000765	regulation of cytoplasmic translation(GO:2000765)
0.0	0.0	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.0	GO:0036060	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:1904903	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.0	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.0	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:0045730	respiratory burst(GO:0045730)
0.0	0.9	GO:0010257	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.0	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.5	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.2	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.0	0.0	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.0	GO:0046851	negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.0	GO:0098930	anterograde axonal transport(GO:0008089) axonal transport(GO:0098930)
0.0	0.0	GO:0090345	cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0	0.0	GO:0021718	pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0	0.0	GO:1900453	negative regulation of long term synaptic depression(GO:1900453)
0.0	0.0	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.0	GO:2001138	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	0.0	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.0	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.2	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.1	GO:0035813	renal sodium excretion(GO:0035812) regulation of renal sodium excretion(GO:0035813) regulation of excretion(GO:0044062)
0.0	0.2	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.0	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.2	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.0	GO:0070673	response to interleukin-18(GO:0070673)
0.0	0.0	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0	0.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:1903817	negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.0	0.2	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.1	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.1	GO:0048305	immunoglobulin secretion(GO:0048305)
0.0	0.0	GO:0031034	myosin filament assembly(GO:0031034)
0.0	1.2	GO:0006661	phosphatidylinositol biosynthetic process(GO:0006661)
0.0	0.0	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.8	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.4	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.0	GO:0002752	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.1	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0099515	vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0	0.0	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.0	GO:0015743	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	2.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	3.0	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	1.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	2.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	2.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.6	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	0.3	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	1.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.3	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.1	0.2	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	0.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.2	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.8	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	4.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.5	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	1.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	1.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.0	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.5	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.1	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	1.0	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	21.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	2.7	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2	1.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	1.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	6.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.7	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.1	3.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.0	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	1.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	1.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.7	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	1.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	2.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.8	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.8	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	6.8	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	3.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	0.7	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	1.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	2.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	2.4	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	2.4	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	1.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	3.3	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	1.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	2.2	PID ALK1 PATHWAY	ALK1 signaling events
0.1	6.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	1.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	8.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	4.2	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.9	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	1.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.5	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	2.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	2.5	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.6	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.7	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.7	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.5	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.1	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	4.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.5	PID FGF PATHWAY	FGF signaling pathway
0.0	0.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	1.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	1.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	1.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.6	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	1.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.8	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	1.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	1.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.9	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	1.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.5	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	2.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	9.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	9.2	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	3.8	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	2.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	2.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.9	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	3.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.6	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3	0.8	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.2	2.7	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	1.4	GO:0030172	troponin C binding(GO:0030172)
0.2	3.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.6	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	2.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	1.0	GO:0000150	recombinase activity(GO:0000150)
0.1	2.0	GO:0004697	protein kinase C activity(GO:0004697)
0.1	1.0	GO:0030957	Tat protein binding(GO:0030957)
0.1	2.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.6	GO:0042731	PH domain binding(GO:0042731)
0.1	1.0	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	1.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.7	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.6	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	1.5	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	1.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.5	GO:0031005	filamin binding(GO:0031005)
0.0	0.5	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.5	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	1.3	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	2.1	GO:0008201	heparin binding(GO:0008201)
0.0	3.2	GO:0003714	transcription corepressor activity(GO:0003714)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	23.3	GO:0005610	laminin-5 complex(GO:0005610)
0.6	1.9	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.6	1.7	GO:0005607	laminin-2 complex(GO:0005607)
0.3	3.1	GO:0030057	desmosome(GO:0030057)
0.3	5.4	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.3	1.7	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.3	1.4	GO:0032449	CBM complex(GO:0032449)
0.3	1.9	GO:0097209	epidermal lamellar body(GO:0097209)
0.3	1.4	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.3	2.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2	11.7	GO:0001533	cornified envelope(GO:0001533)
0.2	4.3	GO:0030056	hemidesmosome(GO:0030056)
0.2	1.0	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.2	1.1	GO:0044326	dendritic spine neck(GO:0044326)
0.1	1.0	GO:1990761	growth cone lamellipodium(GO:1990761)
0.1	0.7	GO:1990425	ryanodine receptor complex(GO:1990425)
0.1	0.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	0.4	GO:0044393	microspike(GO:0044393)
0.1	0.7	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.1	4.6	GO:0045095	keratin filament(GO:0045095)
0.1	1.6	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.4	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1	0.7	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1	0.7	GO:0071438	invadopodium membrane(GO:0071438)
0.1	1.4	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	3.4	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.4	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1	0.4	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.9	GO:0097413	Lewy body(GO:0097413)
0.1	0.2	GO:0044609	DBIRD complex(GO:0044609)
0.1	0.8	GO:0005916	fascia adherens(GO:0005916)
0.1	2.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.3	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1	4.0	GO:0005882	intermediate filament(GO:0005882)
0.1	1.8	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	6.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0	0.9	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0032010	phagolysosome(GO:0032010)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.4	GO:0005827	polar microtubule(GO:0005827)
0.0	0.3	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.0	0.7	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.6	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.2	GO:1990075	periciliary membrane compartment(GO:1990075)
0.0	0.6	GO:0030478	actin cap(GO:0030478)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.8	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	1.0	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.9	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.5	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0070187	telosome(GO:0070187)
0.0	0.4	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.6	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.6	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.4	GO:0032433	filopodium tip(GO:0032433)
0.0	0.2	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0036038	MKS complex(GO:0036038)
0.0	2.2	GO:0005604	basement membrane(GO:0005604)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	0.3	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.4	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0030905	retromer, tubulation complex(GO:0030905)
0.0	0.4	GO:0031082	BLOC complex(GO:0031082)
0.0	0.2	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.2	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:0035976	AP1 complex(GO:0035976)
0.0	0.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.0	3.2	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.8	GO:0031430	M band(GO:0031430)
0.0	1.1	GO:0030175	filopodium(GO:0030175)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.3	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	0.6	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.0	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.3	GO:0097546	ciliary base(GO:0097546)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	9.2	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.3	1.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2	0.7	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2	0.6	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2	0.6	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.2	0.7	GO:0032810	sterol response element binding(GO:0032810)
0.2	2.8	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.2	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.8	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.5	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	1.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.4	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.1	1.4	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	0.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	0.8	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.3	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	0.4	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	0.3	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.4	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.1	1.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.4	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1	0.2	GO:0015039	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1	0.2	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	0.4	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	0.3	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.8	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	1.2	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	0.4	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.2	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	2.0	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.2	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.1	0.5	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.6	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.7	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.4	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	1.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	1.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	1.4	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.5	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	1.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.0	0.4	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.5	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0070404	NADH binding(GO:0070404)
0.0	0.4	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	2.4	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.2	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0002046	opsin binding(GO:0002046)
0.0	0.3	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.2	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.1	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0	0.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	1.1	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.8	GO:0001540	beta-amyloid binding(GO:0001540)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	19.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	2.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	3.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	1.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	2.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	1.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	7.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	2.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	1.3	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.0	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	1.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	3.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	3.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	3.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	3.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.7	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	2.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	1.0	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	2.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.6	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3	4.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	4.9	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.1	2.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	1.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	0.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.9	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	3.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	2.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	2.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	2.2	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.2	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	2.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.7	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.7	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	43.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.6	7.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.5	14.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5	6.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.5	9.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.3	4.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3	3.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	5.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	2.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	6.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	5.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	2.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	4.8	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	2.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	4.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	2.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	2.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	3.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	28.2	GO:0045095	keratin filament(GO:0045095)
0.6	4.6	GO:0005610	laminin-5 complex(GO:0005610)
0.4	1.3	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4	20.9	GO:0001533	cornified envelope(GO:0001533)
0.4	2.0	GO:0036128	CatSper complex(GO:0036128)
0.4	1.5	GO:1990745	EARP complex(GO:1990745)
0.3	2.1	GO:1990357	terminal web(GO:1990357)
0.3	2.7	GO:0035976	AP1 complex(GO:0035976)
0.3	2.3	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.3	2.0	GO:0001939	female pronucleus(GO:0001939)
0.3	1.6	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.3	1.1	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3	4.8	GO:0097386	glial cell projection(GO:0097386)
0.2	0.7	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.2	16.8	GO:0005882	intermediate filament(GO:0005882)
0.2	1.2	GO:1990037	Lewy body core(GO:1990037)
0.2	2.4	GO:0097470	ribbon synapse(GO:0097470)
0.2	3.9	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	6.6	GO:0009925	basal plasma membrane(GO:0009925)
0.2	4.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	12.8	GO:0035580	specific granule lumen(GO:0035580)
0.1	7.6	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.1	4.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	1.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.3	GO:0005588	collagen type V trimer(GO:0005588)
0.1	1.5	GO:0030478	actin cap(GO:0030478)
0.1	7.6	GO:0005604	basement membrane(GO:0005604)
0.1	0.5	GO:0030057	desmosome(GO:0030057) paranodal junction(GO:0033010)
0.1	3.2	GO:0002102	podosome(GO:0002102)
0.1	0.5	GO:0005916	fascia adherens(GO:0005916)
0.1	1.5	GO:0031527	filopodium membrane(GO:0031527)
0.0	1.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	2.5	GO:0031430	M band(GO:0031430)
0.0	0.4	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	5.6	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	6.7	GO:0031901	early endosome membrane(GO:0031901)
0.0	33.1	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	1.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.5	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.5	GO:0036038	MKS complex(GO:0036038)
0.0	1.2	GO:0097546	ciliary base(GO:0097546)
0.0	0.3	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.9	GO:0001650	fibrillar center(GO:0001650)
0.0	0.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	1.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	5.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.5	GO:0005921	gap junction(GO:0005921)
0.0	0.2	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.4	GO:0014704	intercalated disc(GO:0014704)
0.0	0.7	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.3	GO:0000786	nucleosome(GO:0000786)
0.0	6.7	GO:0005925	focal adhesion(GO:0005925)
0.0	1.1	GO:0005814	centriole(GO:0005814)
0.0	0.5	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.5	GO:0005901	caveola(GO:0005901)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:1902769	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.7	3.3	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.6	3.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6	1.7	GO:0097052	tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
0.5	1.5	GO:1903925	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3	2.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	1.0	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.2	0.9	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2	3.1	GO:0051639	actin filament network formation(GO:0051639)
0.2	0.5	GO:0071676	negative regulation of mononuclear cell migration(GO:0071676)
0.2	0.8	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	1.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1	0.4	GO:1904647	response to rotenone(GO:1904647)
0.1	0.6	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1	0.5	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1	2.3	GO:0005513	detection of calcium ion(GO:0005513)
0.1	2.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.7	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	1.1	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	2.6	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	0.3	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1	0.5	GO:0006574	valine catabolic process(GO:0006574)
0.1	0.3	GO:0070512	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1	0.3	GO:0019086	late viral transcription(GO:0019086)
0.1	1.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.1	0.3	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.7	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.1	4.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	7.5	GO:0030449	regulation of complement activation(GO:0030449)
0.1	1.0	GO:0015671	oxygen transport(GO:0015671)
0.1	0.7	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	0.8	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	0.5	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.3	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1	0.5	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.4	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.1	0.8	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.0	0.2	GO:1903935	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0	0.2	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	1.0	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.5	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.2	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
0.0	0.1	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.0	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.8	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.2	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.0	1.4	GO:0043029	T cell homeostasis(GO:0043029)
0.0	3.8	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	2.4	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.6	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.3	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	1.1	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.3	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.7	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	2.4	GO:0002819	regulation of adaptive immune response(GO:0002819)
0.0	2.3	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	1.5	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	1.3	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.2	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.5	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1	0.9	GO:0042126	nitrate metabolic process(GO:0042126)
0.1	1.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.3	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.3	GO:0046102	hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102)
0.1	2.0	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.1	0.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.3	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	0.2	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.1	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.3	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.1	0.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.1	0.3	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	0.5	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.3	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.4	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.4	GO:0015886	heme transport(GO:0015886) xenobiotic transport(GO:0042908)
0.0	0.3	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0038155	interleukin-23-mediated signaling pathway(GO:0038155)
0.0	0.6	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	4.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.2	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.1	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106)
0.0	0.5	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.4	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.5	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.7	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.2	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	1.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	7.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0032474	otolith morphogenesis(GO:0032474)
0.4	1.3	GO:0090244	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.4	1.2	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.3	0.9	GO:0010645	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2	1.2	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2	0.6	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.2	0.8	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.2	0.6	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.2	1.1	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2	0.5	GO:0060940	epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1	0.7	GO:1903906	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1	1.4	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.6	GO:0048861	oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	1.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.7	GO:0051582	peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.6	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1	0.5	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.1	0.4	GO:0071461	cellular response to redox state(GO:0071461)
0.1	1.1	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.3	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.1	1.0	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	0.3	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.1	0.3	GO:0032829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1	0.4	GO:2000697	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1	0.3	GO:0045082	interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1	0.3	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.1	1.1	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	2.8	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.2	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	0.3	GO:0099541	retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1	0.3	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	0.3	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.1	0.4	GO:0090131	mesenchyme migration(GO:0090131)
0.1	0.2	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.3	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0	0.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0	0.3	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.1	GO:0050894	determination of affect(GO:0050894)
0.0	0.1	GO:0061386	closure of optic fissure(GO:0061386)
0.0	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.2	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.2	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.3	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.1	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.4	GO:0070141	response to UV-A(GO:0070141)
0.0	0.3	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.2	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.6	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.9	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.5	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.0	0.1	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.0	0.1	GO:0051039	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0	0.8	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.4	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.2	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	1.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
0.0	0.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.7	GO:0097503	sialylation(GO:0097503)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.7	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0061317	regulation of Wnt signaling pathway involved in heart development(GO:0003307) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0	0.2	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0	0.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.7	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.0	0.3	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.1	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.0	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.1	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.0	0.1	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.0	0.5	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	2.9	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.5	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.3	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.1	GO:0010827	regulation of glucose transport(GO:0010827) regulation of glucose import(GO:0046324)
0.0	0.3	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0016050	vesicle organization(GO:0016050)
0.0	0.5	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.2	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.3	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.4	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.1	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.2	GO:0006531	aspartate metabolic process(GO:0006531)
0.0	0.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0006097	glyoxylate cycle(GO:0006097)
0.0	0.1	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.2	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	2.9	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.1	GO:0061083	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.0	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.6	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.4	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.6	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.0	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	0.3	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.7	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
1.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.3	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	0.7	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.6	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	2.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.5	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	3.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	1.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	27.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	4.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	2.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	4.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.3	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.6	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
0.7	4.4	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.7	11.6	GO:0051639	actin filament network formation(GO:0051639)
0.6	9.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.5	2.4	GO:0060356	leucine import(GO:0060356)
0.5	1.4	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4	3.5	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.4	2.3	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3	3.7	GO:0031584	activation of phospholipase D activity(GO:0031584) apical protein localization(GO:0045176)
0.3	1.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2	0.7	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.2	1.7	GO:0015866	ADP transport(GO:0015866)
0.2	0.6	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.2	0.7	GO:1903288	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.2	2.1	GO:0051764	actin crosslink formation(GO:0051764)
0.2	0.5	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2	0.5	GO:0071109	superior temporal gyrus development(GO:0071109)
0.2	0.8	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	0.7	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.4	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.9	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1	0.9	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1	1.4	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1	0.4	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.1	0.5	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	0.3	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1	0.4	GO:0031291	Ran protein signal transduction(GO:0031291)
0.1	0.4	GO:1990834	response to odorant(GO:1990834)
0.1	1.8	GO:0032060	bleb assembly(GO:0032060)
0.1	0.5	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1	0.5	GO:0032328	alanine transport(GO:0032328)
0.1	0.7	GO:0016584	nucleosome positioning(GO:0016584)
0.1	0.9	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	2.7	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1	1.1	GO:0002003	angiotensin maturation(GO:0002003)
0.1	0.9	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.1	0.2	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.1	0.3	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.1	7.5	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.1	1.2	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.3	GO:0035617	stress granule disassembly(GO:0035617)
0.1	0.5	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.1	0.6	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	1.5	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.2	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.5	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.6	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0	0.4	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.0	0.1	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.5	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	1.0	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.7	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.1	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.3	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.3	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.9	GO:0048512	circadian behavior(GO:0048512)
0.0	0.1	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0	0.1	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.4	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.2	GO:0060707	trophoblast giant cell differentiation(GO:0060707)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.2	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.9	2.6	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.8	2.4	GO:0042938	dipeptide transport(GO:0042938)
0.7	2.1	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.5	1.5	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5	3.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.4	1.9	GO:0051622	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.4	2.6	GO:0033590	response to cobalamin(GO:0033590)
0.4	1.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3	1.3	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.3	1.7	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	2.4	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3	0.8	GO:0015680	intracellular copper ion transport(GO:0015680)
0.3	3.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.3	2.0	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2	1.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2	2.5	GO:0002934	desmosome organization(GO:0002934)
0.2	0.7	GO:1903722	regulation of centriole elongation(GO:1903722)
0.2	0.9	GO:2000537	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2	0.9	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.2	0.8	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.2	0.8	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2	0.2	GO:1902567	negative regulation of eosinophil activation(GO:1902567)
0.2	1.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.2	1.8	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.2	1.0	GO:0034436	glycoprotein transport(GO:0034436)
0.2	1.0	GO:0032252	secretory granule localization(GO:0032252)
0.2	2.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.2	0.3	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.2	0.5	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
0.1	0.9	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.4	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	5.4	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	1.2	GO:0003344	pericardium morphogenesis(GO:0003344)
0.1	1.0	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.4	GO:1905154	negative regulation of membrane invagination(GO:1905154)
0.1	1.1	GO:0015705	iodide transport(GO:0015705)
0.1	0.6	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.1	0.8	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1	0.5	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	2.8	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.3	GO:0060374	mast cell differentiation(GO:0060374)
0.1	0.3	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.1	0.5	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166) positive regulation of t-circle formation(GO:1904431)
0.1	0.8	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	0.2	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1	0.3	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.1	0.1	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.1	0.9	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.8	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.1	2.4	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1	0.2	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1	0.4	GO:0098706	ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	0.4	GO:0051136	regulation of NK T cell differentiation(GO:0051136)
0.1	0.1	GO:1902573	positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1	1.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	3.3	GO:0006298	mismatch repair(GO:0006298)
0.1	1.2	GO:0008228	opsonization(GO:0008228)
0.1	0.2	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1	0.6	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.4	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.1	0.2	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.6	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1	1.5	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.3	GO:0044336	embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1	0.2	GO:0061056	sclerotome development(GO:0061056)
0.1	0.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.3	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.1	0.2	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.5	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.0	0.1	GO:0070781	arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0	0.6	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.3	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.0	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.3	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.8	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.2	GO:0072143	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.0	0.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.3	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.7	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.5	GO:0042118	endothelial cell activation(GO:0042118)
0.0	3.7	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.8	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	1.5	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.2	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	1.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0097501	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0	3.2	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	1.2	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.2	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.5	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	1.3	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.2	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.5	GO:0003334	keratinocyte development(GO:0003334)
0.0	1.5	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.1	GO:0006836	neurotransmitter transport(GO:0006836)
0.0	0.2	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0	0.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.3	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.4	GO:0000075	cell cycle checkpoint(GO:0000075)
0.0	0.1	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.2	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.1	GO:1903061	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.7	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:2001162	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0	2.3	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.5	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.7	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0090298	late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
0.0	0.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.5	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.3	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.0	GO:0021779	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.2	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.0	GO:0001694	histamine biosynthetic process(GO:0001694)
0.0	0.0	GO:0051866	general adaptation syndrome(GO:0051866)
0.0	0.4	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0070253	somatostatin secretion(GO:0070253)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	5.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	2.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	2.1	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.8	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	1.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	1.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	2.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.8	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	6.0	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
1.2	4.7	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.1	10.2	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.5	1.5	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.4	4.8	GO:0039706	co-receptor binding(GO:0039706)
0.3	1.8	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.3	5.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.2	1.2	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.2	4.6	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.2	6.5	GO:0070064	proline-rich region binding(GO:0070064)
0.2	3.8	GO:0050786	RAGE receptor binding(GO:0050786)
0.2	0.9	GO:0030492	hemoglobin binding(GO:0030492)
0.1	1.0	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	0.6	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	3.5	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	6.1	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1	0.8	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.8	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.1	0.3	GO:0004803	transposase activity(GO:0004803)
0.1	7.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	5.3	GO:0005518	collagen binding(GO:0005518)
0.1	0.2	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.7	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.1	5.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.7	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	1.6	GO:0005109	frizzled binding(GO:0005109)
0.0	0.6	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	4.3	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.7	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.5	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.2	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	8.4	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	2.1	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.0	0.7	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	1.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0035497	cAMP response element binding(GO:0035497)

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
0.4	ST STAT3 PATHWAY	STAT3 Pathway
1.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.7	PID NCADHERIN PATHWAY	N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	3.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:0005826	actomyosin contractile ring(GO:0005826)
0.7	2.1	GO:0005588	collagen type V trimer(GO:0005588)
0.7	4.0	GO:1990584	cardiac Troponin complex(GO:1990584)
0.5	6.4	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.4	2.6	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.4	7.5	GO:0005861	troponin complex(GO:0005861)
0.4	4.6	GO:0097512	cardiac myofibril(GO:0097512)
0.4	7.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.4	7.6	GO:0005859	muscle myosin complex(GO:0005859)
0.3	1.6	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3	1.4	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.3	3.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.3	16.3	GO:0031672	A band(GO:0031672)
0.2	3.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	0.8	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2	3.8	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	1.3	GO:0071953	elastic fiber(GO:0071953)
0.1	1.0	GO:0070852	cell body fiber(GO:0070852)
0.1	0.6	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	1.3	GO:0031674	I band(GO:0031674)
0.1	0.9	GO:0030061	mitochondrial crista(GO:0030061)
0.1	19.3	GO:0030018	Z disc(GO:0030018)
0.1	0.6	GO:0014802	terminal cisterna(GO:0014802)
0.1	3.4	GO:0034451	centriolar satellite(GO:0034451)
0.1	2.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	1.0	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.1	0.3	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	1.3	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	2.8	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	0.4	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.8	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.6	GO:0061617	MICOS complex(GO:0061617)
0.1	0.7	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	0.5	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.1	0.2	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.1	1.5	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.7	GO:0030175	filopodium(GO:0030175)
0.1	0.2	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.1	2.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.2	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1	0.5	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	1.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.3	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.3	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.3	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.9	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.7	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.2	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.2	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.5	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.6	GO:0000124	SAGA complex(GO:0000124)
0.0	0.4	GO:0097443	sorting endosome(GO:0097443)
0.0	0.6	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.8	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.3	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	1.0	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	1.8	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	1.2	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.8	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.5	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.4	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0032044	DSIF complex(GO:0032044)
0.0	0.3	GO:0005638	lamin filament(GO:0005638)
0.0	0.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.5	GO:0034709	methylosome(GO:0034709)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.5	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.6	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.3	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	1.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.6	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	2.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.5	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.0	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	2.5	GO:0015629	actin cytoskeleton(GO:0015629)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.6	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	1.3	GO:0030016	myofibril(GO:0030016)
0.0	0.6	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	1.9	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	3.0	GO:0043197	dendritic spine(GO:0043197)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.9	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	2.3	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.3	GO:0043218	compact myelin(GO:0043218)
0.0	1.0	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	1.8	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.0	7.0	GO:0005925	focal adhesion(GO:0005925)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.0	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.3	GO:0005819	spindle(GO:0005819)
0.0	3.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0009925	basal plasma membrane(GO:0009925)
0.0	1.3	GO:0055037	recycling endosome(GO:0055037)
0.0	0.6	GO:0043195	terminal bouton(GO:0043195)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	9.4	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.8	2.4	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.7	2.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.7	2.1	GO:0010645	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.7	2.0	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.4	1.2	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3	1.0	GO:0061386	closure of optic fissure(GO:0061386)
0.3	0.9	GO:1904395	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.3	0.3	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3	0.9	GO:1904328	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3	1.1	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3	1.8	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3	1.0	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.2	1.5	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2	7.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.2	0.6	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.2	4.4	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.2	1.4	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	0.5	GO:0048611	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.2	0.6	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.1	0.6	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.4	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1	0.4	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1	0.1	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.1	0.4	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.1	0.4	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1	0.3	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.1	0.4	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	0.8	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.5	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.4	GO:2000697	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1	0.6	GO:0035803	egg coat formation(GO:0035803)
0.1	0.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.5	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	0.1	GO:2000196	positive regulation of female gonad development(GO:2000196)
0.1	0.2	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
0.1	0.2	GO:0072229	carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.1	0.3	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.2	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.1	0.3	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.4	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1	1.8	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1	1.0	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1	1.1	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.0	0.4	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.9	GO:0032060	bleb assembly(GO:0032060)
0.0	0.7	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.4	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.4	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0	0.3	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.4	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0002331	pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.3	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.2	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.1	GO:0072423	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0	0.1	GO:0035548	gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0	0.4	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.3	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.0	1.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.5	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.3	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.2	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.1	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.0	1.5	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.5	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.1	GO:0007418	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.8	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.2	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.1	GO:0042938	dipeptide transport(GO:0042938)
0.0	3.7	GO:0042594	response to starvation(GO:0042594)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.4	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0001712	ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0	0.3	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0043988	histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0	0.1	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.5	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.3	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.2	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.3	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.2	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.2	GO:0060004	reflex(GO:0060004)
0.0	0.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.5	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.2	GO:0050613	delta14-sterol reductase activity(GO:0050613)
1.1	3.4	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
1.1	14.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.8	2.5	GO:0004603	phenylethanolamine N-methyltransferase activity(GO:0004603)
0.8	3.2	GO:0004998	transferrin receptor activity(GO:0004998)
0.7	2.8	GO:0004743	pyruvate kinase activity(GO:0004743)
0.5	1.6	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5	3.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.5	2.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.5	1.5	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.5	1.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.5	3.7	GO:0030172	troponin C binding(GO:0030172)
0.4	1.3	GO:0016731	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.4	3.4	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4	1.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.3	9.5	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.3	4.0	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3	1.3	GO:0030492	hemoglobin binding(GO:0030492)
0.3	1.6	GO:0031708	endothelin B receptor binding(GO:0031708)
0.3	0.9	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.2	0.7	GO:0002113	interleukin-33 binding(GO:0002113)
0.2	1.4	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2	2.6	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.2	1.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.2	5.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	1.2	GO:0005499	vitamin D binding(GO:0005499)
0.2	5.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2	0.6	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2	2.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.2	0.9	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.2	2.9	GO:0005518	collagen binding(GO:0005518)
0.2	3.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	1.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.8	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2	1.3	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2	1.0	GO:0098821	BMP receptor activity(GO:0098821)
0.2	1.3	GO:0004064	arylesterase activity(GO:0004064)
0.2	0.6	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.1	4.6	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.7	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	6.1	GO:0050699	WW domain binding(GO:0050699)
0.1	0.7	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.5	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	1.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.7	GO:0017018	myosin phosphatase activity(GO:0017018)
0.1	0.5	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	0.5	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.1	0.4	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.5	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	0.4	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	0.8	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.3	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.5	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.4	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	0.9	GO:0051525	NFAT protein binding(GO:0051525)
0.1	1.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	15.3	GO:0005178	integrin binding(GO:0005178)
0.1	1.8	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	4.3	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	2.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	0.2	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.1	0.3	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	1.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.4	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.6	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	3.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	1.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.3	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1	0.4	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	0.3	GO:0004882	androgen receptor activity(GO:0004882)
0.1	0.6	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.7	GO:0032393	MHC class I receptor activity(GO:0032393)
0.1	0.3	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.5	GO:0004969	histamine receptor activity(GO:0004969)
0.1	0.4	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.3	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.7	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.7	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.3	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.9	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0051373	FATZ binding(GO:0051373)
0.0	0.4	GO:0015232	heme transporter activity(GO:0015232)
0.0	1.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.5	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.4	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0	0.3	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.8	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.3	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.4	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.1	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0	2.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	1.0	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	1.3	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.4	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.2	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.2	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	2.9	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.2	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	2.9	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.9	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.4	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	2.1	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.6	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	1.6	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.3	GO:0070513	death domain binding(GO:0070513)
0.0	1.0	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	1.1	GO:0019843	rRNA binding(GO:0019843)
0.0	0.4	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.3	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0060229	phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0	0.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.6	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	1.0	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.7	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.5	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.4	GO:0002039	p53 binding(GO:0002039)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0044393	microspike(GO:0044393)
0.2	0.7	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
0.2	0.5	GO:0098536	deuterosome(GO:0098536)
0.2	0.5	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.2	1.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	0.6	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.8	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.4	GO:0030689	Noc complex(GO:0030689)
0.1	0.4	GO:0031523	Myb complex(GO:0031523)
0.1	1.0	GO:0045179	apical cortex(GO:0045179)
0.1	0.8	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.4	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.9	GO:0070187	telosome(GO:0070187)
0.1	0.4	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.8	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.2	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.6	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	0.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	5.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	0.3	GO:0032021	NELF complex(GO:0032021)
0.1	0.3	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	1.4	GO:0031143	pseudopodium(GO:0031143)
0.0	0.5	GO:0070938	contractile ring(GO:0070938)
0.0	0.4	GO:0000322	storage vacuole(GO:0000322)
0.0	0.4	GO:0070652	HAUS complex(GO:0070652)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.3	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	1.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.1	GO:0020005	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0	0.8	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.9	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	1.1	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.3	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.6	GO:0071437	invadopodium(GO:0071437)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	1.7	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.4	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.8	GO:0014704	intercalated disc(GO:0014704)
0.0	0.1	GO:0034709	methylosome(GO:0034709)
0.0	1.1	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	1.6	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	1.0	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.7	GO:0031514	motile cilium(GO:0031514)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.5	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	0.5	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	2.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	3.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	1.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.8	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	3.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	2.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	5.8	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	2.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	1.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.0	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	1.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.7	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	4.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.9	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	0.5	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	1.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	2.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	2.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	3.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	3.8	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	1.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	2.6	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	2.5	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.2	2.8	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	4.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.2	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	3.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	2.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	1.5	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1	1.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	0.9	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	2.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	2.4	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	2.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	0.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	2.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	1.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	2.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.8	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	1.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	2.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.8	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.6	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	2.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	3.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.0	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.6	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	3.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	7.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.7	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	0.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.8	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	1.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	1.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.8	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.4	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	1.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.0	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.2	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	7.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.3	0.8	GO:0051684	maintenance of Golgi location(GO:0051684)
0.3	0.8	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.3	1.3	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2	0.7	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2	2.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	1.2	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.2	0.9	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	1.2	GO:1900045	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.2	0.5	GO:0072092	olfactory bulb mitral cell layer development(GO:0061034) ureteric bud invasion(GO:0072092)
0.2	0.5	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1	0.4	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.4	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	1.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.6	GO:0051026	chiasma assembly(GO:0051026)
0.1	0.4	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.2	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1	1.0	GO:0030903	notochord development(GO:0030903)
0.1	0.2	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	1.2	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.7	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.4	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.3	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.0	0.4	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	3.8	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.2	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.2	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.2	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.4	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.2	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0	0.4	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.6	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.2	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0030916	otic vesicle formation(GO:0030916)
0.0	0.4	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.1	GO:0060737	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.1	GO:0035063	nuclear speck organization(GO:0035063)
0.0	1.2	GO:0007286	spermatid development(GO:0007286)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	7.4	GO:0050436	microfibril binding(GO:0050436)
1.2	3.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
1.1	4.3	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.9	12.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.8	3.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.5	2.0	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.5	2.9	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	2.5	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.3	1.4	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.3	3.7	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3	0.8	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.3	0.8	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2	2.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	1.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.2	1.5	GO:0001515	opioid peptide activity(GO:0001515)
0.2	0.8	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2	1.1	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.2	0.8	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	1.1	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.2	0.9	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.2	1.8	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	4.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	1.6	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	1.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	2.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.5	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1	0.3	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	0.8	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.5	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.4	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.5	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.5	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	0.7	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	1.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1	0.3	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1	0.9	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	0.7	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.1	2.1	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.3	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	0.2	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.5	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	1.8	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.5	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.4	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	1.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	1.5	GO:0031489	myosin V binding(GO:0031489)
0.1	0.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	1.5	GO:0071949	FAD binding(GO:0071949)
0.0	0.3	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	1.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	1.2	GO:0015248	sterol transporter activity(GO:0015248)
0.0	2.0	GO:0070888	E-box binding(GO:0070888)
0.0	1.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0033265	choline binding(GO:0033265)
0.0	1.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.8	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	3.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.6	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.0	2.4	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.4	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.2	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.6	GO:0005112	Notch binding(GO:0005112)
0.0	1.2	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	1.2	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	2.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.6	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	1.1	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	2.9	GO:0019887	protein kinase regulator activity(GO:0019887)
0.0	0.3	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	4.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	6.5	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	18.5	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
1.0	3.1	GO:0034146	B-1 B cell homeostasis(GO:0001922) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.7	3.5	GO:0030070	insulin processing(GO:0030070)
0.7	2.0	GO:0006597	spermine biosynthetic process(GO:0006597)
0.6	1.8	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.5	1.5	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4	2.2	GO:0070295	renal water absorption(GO:0070295)
0.4	1.2	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.4	1.1	GO:0097359	UDP-glucosylation(GO:0097359)
0.3	1.0	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.3	1.3	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3	1.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3	2.2	GO:0008218	bioluminescence(GO:0008218)
0.3	0.8	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.3	2.8	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3	2.9	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.3	1.0	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2	1.6	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2	2.4	GO:0051918	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of fibrinolysis(GO:0051918)
0.2	0.9	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.2	1.3	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.2	0.8	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2	0.7	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.2	1.4	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.2	1.6	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.2	0.9	GO:0008204	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2	1.2	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.2	2.3	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1	1.3	GO:2001300	lipoxin metabolic process(GO:2001300)
0.1	1.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.8	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	2.0	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1	0.7	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	2.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.4	GO:0006172	ADP biosynthetic process(GO:0006172)
0.1	1.9	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.1	0.5	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.4	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.1	0.7	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.9	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1	0.3	GO:0071301	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1	1.7	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	7.6	GO:0006953	acute-phase response(GO:0006953)
0.1	0.9	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	5.6	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	1.3	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.1	0.3	GO:0061110	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1	1.0	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.1	1.3	GO:0006449	regulation of translational termination(GO:0006449)
0.1	0.4	GO:0035063	nuclear speck organization(GO:0035063)
0.1	1.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	0.8	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	0.3	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1	0.3	GO:0007525	somatic muscle development(GO:0007525)
0.1	1.0	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.9	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	1.3	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	0.8	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.3	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.6	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.1	0.6	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	0.3	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.1	0.6	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	1.0	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.8	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.9	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	0.4	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.9	GO:0030336	negative regulation of cell migration(GO:0030336) negative regulation of cell motility(GO:2000146)
0.0	0.6	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.2	GO:2000230	negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0	0.4	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.5	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.2	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	1.3	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.4	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.4	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0070253	somatostatin secretion(GO:0070253)
0.0	0.3	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0	0.5	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.3	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.5	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.9	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0009258	10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0	0.2	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158) regulation of miRNA metabolic process(GO:2000628)
0.0	0.6	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	1.8	GO:0006342	chromatin silencing(GO:0006342)
0.0	0.5	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.3	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.2	GO:0010666	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.1	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.6	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.2	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.4	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.2	GO:0010629	negative regulation of gene expression(GO:0010629)
0.0	0.9	GO:0008542	visual learning(GO:0008542)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.3	GO:0021915	neural tube development(GO:0021915)
0.0	1.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.3	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	1.1	GO:0070268	cornification(GO:0070268)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:1901859	negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.5	1.6	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.2	1.4	GO:0001661	conditioned taste aversion(GO:0001661)
0.2	0.9	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.1	0.2	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1	1.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	1.0	GO:0035878	nail development(GO:0035878)
0.1	0.8	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1	0.4	GO:0071896	negative regulation of hippo signaling(GO:0035331) protein localization to adherens junction(GO:0071896)
0.0	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	1.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.7	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.4	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.1	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.0	0.5	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.4	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.2	GO:0035897	proteolysis in other organism(GO:0035897)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.2	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.1	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.0	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0	0.2	GO:0045792	negative regulation of cell size(GO:0045792)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.0	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	5.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.8	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.5	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	1.9	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	0.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	2.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	3.0	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.9	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.2	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.9	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.8	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.8	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	2.8	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.4	GO:0016403	dimethylargininase activity(GO:0016403)
0.1	0.2	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.3	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.2	GO:0015254	glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.0	1.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	1.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0031208	POZ domain binding(GO:0031208)
0.0	0.4	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.4	GO:0005522	profilin binding(GO:0005522)
0.0	0.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	1.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.6	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.3	2.3	GO:0097209	epidermal lamellar body(GO:0097209)
0.3	10.2	GO:0030057	desmosome(GO:0030057)
0.3	0.9	GO:0002081	outer acrosomal membrane(GO:0002081)
0.3	4.3	GO:0005922	connexon complex(GO:0005922)
0.2	0.9	GO:0070695	FHF complex(GO:0070695)
0.2	1.5	GO:0098845	postsynaptic endosome(GO:0098845)
0.2	1.4	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	1.2	GO:0033269	internode region of axon(GO:0033269)
0.2	0.7	GO:0043259	laminin-10 complex(GO:0043259)
0.1	2.9	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.5	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.1	0.6	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	5.6	GO:0045095	keratin filament(GO:0045095)
0.1	0.9	GO:0045179	apical cortex(GO:0045179)
0.1	0.4	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.1	0.8	GO:0035976	AP1 complex(GO:0035976)
0.1	0.3	GO:0030689	Noc complex(GO:0030689)
0.1	0.5	GO:1990357	terminal web(GO:1990357)
0.1	0.1	GO:0030135	coated vesicle(GO:0030135)
0.1	0.6	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.8	GO:0016342	catenin complex(GO:0016342)
0.1	5.2	GO:0005882	intermediate filament(GO:0005882)
0.1	0.4	GO:0061689	tricellular tight junction(GO:0061689)
0.1	2.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.5	GO:0061617	MICOS complex(GO:0061617)
0.1	0.6	GO:0032039	integrator complex(GO:0032039)
0.1	1.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.1	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	3.7	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.6	GO:0097433	dense body(GO:0097433)
0.0	1.0	GO:0031143	pseudopodium(GO:0031143)
0.0	4.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.3	GO:0033391	chromatoid body(GO:0033391)
0.0	4.0	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.3	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.5	GO:0032433	filopodium tip(GO:0032433)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.6	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	1.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.0	0.9	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.1	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.0	0.2	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.4	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.4	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.9	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.2	GO:0098562	cytoplasmic side of membrane(GO:0098562)
0.0	0.4	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	1.3	GO:0031594	neuromuscular junction(GO:0031594)
0.0	2.4	GO:0005795	Golgi stack(GO:0005795)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	1.2	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.9	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.3	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.1	GO:0070187	telosome(GO:0070187)
0.0	0.4	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.2	GO:0034709	methylosome(GO:0034709)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.4	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.6	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.8	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	1.3	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	3.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2	4.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	2.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	3.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	2.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	1.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	2.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.7	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.1	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.0	0.4	GO:0035976	AP1 complex(GO:0035976)
0.0	0.3	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.5	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0044292	dendrite terminus(GO:0044292)
0.0	1.1	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.1	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.2	GO:0045160	myosin I complex(GO:0045160)
0.0	1.5	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.2	GO:0033063	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.8	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.3	GO:0045179	apical cortex(GO:0045179)
0.0	0.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.2	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	1.3	GO:0031093	platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.2	GO:0039706	co-receptor binding(GO:0039706)
0.3	3.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.3	3.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	1.8	GO:1990254	keratin filament binding(GO:1990254)
0.3	1.9	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	3.3	GO:0045499	chemorepellent activity(GO:0045499)
0.2	2.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	0.7	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2	2.5	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	1.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	3.8	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.6	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.1	0.5	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.1	1.0	GO:0045545	syndecan binding(GO:0045545)
0.1	1.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	2.9	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	1.1	GO:0045159	myosin II binding(GO:0045159)
0.1	0.9	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	1.0	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1	6.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.7	GO:0008430	selenium binding(GO:0008430)
0.1	0.4	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	0.2	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	2.3	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.1	0.2	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	0.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	0.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	3.1	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1	0.3	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.3	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.3	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	0.3	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.7	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	1.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.3	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0	0.4	GO:0043426	MRF binding(GO:0043426)
0.0	0.7	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	1.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	1.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	1.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.8	GO:0070410	co-SMAD binding(GO:0070410)
0.0	2.3	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.3	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	2.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0015266	protein channel activity(GO:0015266)
0.0	1.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0017057	glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0	0.3	GO:0031005	filamin binding(GO:0031005)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.7	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	4.6	GO:0003924	GTPase activity(GO:0003924)
0.0	0.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.5	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.2	GO:0070330	aromatase activity(GO:0070330)
0.0	1.4	GO:0005178	integrin binding(GO:0005178)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	1.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	2.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	1.2	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.3	1.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3	1.3	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.2	0.6	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2	0.8	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1	0.4	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.1	0.6	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.1	0.4	GO:0005846	nuclear cap binding complex(GO:0005846)
0.1	0.4	GO:0032044	DSIF complex(GO:0032044)
0.1	0.9	GO:0005638	lamin filament(GO:0005638)
0.1	1.7	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.3	GO:0070876	SOSS complex(GO:0070876)
0.1	0.3	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	0.3	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	0.5	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.3	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1	0.4	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	1.9	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1	0.2	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.0	1.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.3	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.0	0.3	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0034657	GID complex(GO:0034657)
0.0	0.5	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.9	GO:0097346	INO80-type complex(GO:0097346)
0.0	0.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.4	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.3	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:1990037	Lewy body core(GO:1990037)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	1.1	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	1.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:1902560	GMP reductase complex(GO:1902560)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.4	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.7	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0019815	B cell receptor complex(GO:0019815)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	6.6	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.5	10.2	GO:0032433	filopodium tip(GO:0032433)
0.4	1.4	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2	1.0	GO:0045179	apical cortex(GO:0045179)
0.2	0.9	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	2.8	GO:0043203	axon hillock(GO:0043203)
0.2	4.2	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.8	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	4.5	GO:0005605	basal lamina(GO:0005605)
0.1	1.0	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	13.4	GO:0005923	bicellular tight junction(GO:0005923)
0.1	2.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	4.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.8	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.2	GO:0034457	Mpp10 complex(GO:0034457)
0.0	10.5	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.7	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	1.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	4.9	GO:0043204	perikaryon(GO:0043204)
0.0	10.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.8	GO:0030673	axolemma(GO:0030673)
0.0	2.2	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	3.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	3.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	4.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	5.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.4	10.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	39.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.3	4.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	8.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	6.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	7.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	6.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	3.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	7.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2	1.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	5.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	8.0	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	8.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	7.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	2.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	2.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	3.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	6.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	4.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	4.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	1.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	2.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.8	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	1.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.1	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.7	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	4.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.9	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	2.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	3.4	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.2	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	2.3	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	9.3	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.6	1.9	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5	1.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.4	4.1	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4	1.5	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.3	2.7	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.3	1.0	GO:0071409	negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.3	1.5	GO:0019323	pentose catabolic process(GO:0019323)
0.3	1.6	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.3	0.8	GO:1903570	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3	1.3	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3	0.8	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3	2.3	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2	0.7	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2	0.6	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.2	1.2	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.2	1.2	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.2	0.8	GO:0086053	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2	0.4	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.2	1.3	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.2	0.9	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.2	1.6	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.2	1.8	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.2	0.5	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2	1.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.2	0.8	GO:1901908	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2	1.4	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2	0.8	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.7	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.4	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1	0.6	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.1	0.7	GO:0060356	leucine import(GO:0060356)
0.1	1.0	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.1	0.6	GO:0035026	leading edge cell differentiation(GO:0035026)
0.1	0.5	GO:1903936	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1	0.5	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.5	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.4	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1	0.3	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1	0.3	GO:0045658	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1	0.4	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1	0.3	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.1	1.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.1	0.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.9	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.6	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1	1.4	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.0	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.5	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	0.3	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	1.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.5	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1	0.3	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	0.8	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	0.3	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.1	0.8	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.7	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	1.1	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.8	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.2	GO:0033386	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1	0.6	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.9	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.2	GO:0019417	sulfur oxidation(GO:0019417)
0.1	0.8	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.1	0.4	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1	0.7	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.3	GO:0060992	response to fungicide(GO:0060992)
0.1	1.0	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	0.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.2	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1	0.2	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.1	0.5	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.3	GO:0070384	growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) Harderian gland development(GO:0070384)
0.1	0.3	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1	1.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	0.4	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.4	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.1	0.3	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.0	0.1	GO:0071529	cementum mineralization(GO:0071529)
0.0	0.4	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	0.2	GO:1990504	dense core granule exocytosis(GO:1990504)
0.0	0.6	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.2	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.3	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.0	0.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.3	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.4	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.3	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0	0.1	GO:2000681	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0	1.8	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	2.3	GO:0035904	aorta development(GO:0035904)
0.0	0.5	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.3	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.0	1.0	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.7	GO:0006907	pinocytosis(GO:0006907)
0.0	0.6	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.0	0.5	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.2	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	1.5	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.0	0.9	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.8	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.6	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0	0.2	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0	0.2	GO:0015692	lead ion transport(GO:0015692)
0.0	0.2	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.2	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.6	GO:0048569	post-embryonic organ development(GO:0048569)
0.0	0.1	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0	0.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.0	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.2	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.0	0.1	GO:0051029	rRNA transport(GO:0051029)
0.0	0.7	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.7	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.4	GO:0001553	luteinization(GO:0001553)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.1	GO:1990523	negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523)
0.0	0.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
0.0	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.0	0.5	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.2	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.1	GO:1904617	regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0	1.5	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.3	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0	0.5	GO:0032292	negative regulation of cardiac muscle cell apoptotic process(GO:0010667) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.4	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.0	0.6	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.3	GO:0022038	corpus callosum development(GO:0022038)
0.0	1.3	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.4	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.7	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.1	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.3	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0	0.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	0.7	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.2	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.7	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.2	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.3	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.8	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.8	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.8	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.4	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:1902460	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0	0.1	GO:0035721	intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.3	GO:0007029	endoplasmic reticulum organization(GO:0007029)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	2.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	2.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	2.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	3.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	0.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.8	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.8	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.7	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.5	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.8	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	1.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME NUCLEOTIDE EXCISION REPAIR	Genes involved in Nucleotide Excision Repair
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	2.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.5	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.6	1.8	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.5	2.2	GO:0015254	glycerol channel activity(GO:0015254)
0.5	2.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.4	1.3	GO:0005174	CD40 receptor binding(GO:0005174)
0.4	1.1	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3	1.3	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3	1.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3	0.9	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.3	1.9	GO:0008142	oxysterol binding(GO:0008142)
0.3	1.6	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.3	3.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	2.3	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.2	1.3	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2	1.3	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2	0.9	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2	0.5	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.2	0.9	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.2	1.5	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2	1.6	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.2	1.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.1	16.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.9	GO:0043199	sulfate binding(GO:0043199)
0.1	0.7	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	0.5	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	2.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.1	1.0	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.3	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1	1.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.9	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.5	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	1.7	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	0.5	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	1.3	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.7	GO:0034452	dynactin binding(GO:0034452)
0.1	0.8	GO:0022851	benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1	0.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	0.2	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	0.9	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.8	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.7	GO:0070016	gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0	0.4	GO:0031013	troponin I binding(GO:0031013)
0.0	0.3	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	2.0	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	3.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.4	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	1.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.9	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.8	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.3	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0	0.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.2	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.8	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.0	0.7	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0070330	aromatase activity(GO:0070330)
0.0	0.7	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	1.6	GO:0016853	isomerase activity(GO:0016853)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	4.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	2.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	2.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	4.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	1.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	7.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.6	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	2.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.7	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	1.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	1.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.0	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	1.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	1.0	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	2.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	2.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.5	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	1.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	2.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.7	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.1	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	2.2	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	26.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
1.3	80.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
1.3	20.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
1.1	2.3	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
1.1	13.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
1.0	1.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.9	19.7	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.9	6.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.8	16.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.7	16.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.6	8.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.6	6.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.6	58.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.6	4.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.6	8.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.6	13.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.5	10.9	REACTOME KINESINS	Genes involved in Kinesins
0.5	14.7	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.5	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4	16.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.4	8.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	3.6	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.4	4.0	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.4	7.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.4	10.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.4	3.2	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.4	6.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3	7.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3	1.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	5.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3	4.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3	4.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.3	6.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.3	8.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3	6.1	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	1.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3	10.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.3	3.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	4.0	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	6.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	4.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	6.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2	3.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	3.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.2	3.4	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.2	5.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	2.0	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.2	2.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	1.9	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.2	3.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2	2.9	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2	6.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2	4.7	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.2	3.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	1.8	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	6.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	5.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	0.3	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	5.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	2.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	3.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	2.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	12.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	3.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	2.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	4.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	5.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	5.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	1.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	2.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	5.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	3.7	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	2.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	3.1	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	1.6	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	2.8	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.1	1.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.8	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	4.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	2.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	1.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.6	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	0.5	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.1	2.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	1.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	1.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	0.4	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	1.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.7	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	2.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	7.2	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.9	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	3.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	10.9	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	5.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.7	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.3	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	1.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.2	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	1.6	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.8	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	1.4	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	3.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	2.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.7	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	1.9	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.6	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME NUCLEOTIDE EXCISION REPAIR	Genes involved in Nucleotide Excision Repair
0.0	0.9	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	1.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.6	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.0	3.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.7	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.7	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.8	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.3	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.3	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	101.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.4	4.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.4	52.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.2	6.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	3.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.2	6.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	2.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.2	4.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	3.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	3.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	2.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	11.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	5.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	4.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	3.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	1.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	5.4	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	4.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	4.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	4.9	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	28.5	NABA COLLAGENS	Genes encoding collagen proteins
0.4	20.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.3	16.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	3.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	4.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	4.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	6.8	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	15.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	5.1	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	5.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	2.4	PID ALK1 PATHWAY	ALK1 signaling events
0.1	2.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	1.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	2.7	PID INSULIN PATHWAY	Insulin Pathway
0.1	3.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	2.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	1.0	PID IGF1 PATHWAY	IGF1 pathway
0.1	5.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	0.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	0.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	1.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	2.8	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	3.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.6	ST STAT3 PATHWAY	STAT3 Pathway
0.0	2.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	10.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.0	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	3.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.5	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.8	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.8	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	7.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	1.3	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.2	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.3	REACTOME KINESINS	Genes involved in Kinesins

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.4	GO:0035976	AP1 complex(GO:0035976)
0.1	2.0	GO:0030056	hemidesmosome(GO:0030056)
0.1	1.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	1.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.9	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.4	GO:0000145	exocyst(GO:0000145)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	2.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.6	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	3.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	2.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	4.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	1.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	2.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.0	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.0	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.5	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	1.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.0	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	0.3	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.2	5.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	4.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	5.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	5.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	1.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.2	5.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	9.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	3.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	6.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	4.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	4.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	2.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	2.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	3.4	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.1	0.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	0.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.0	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.1	0.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	0.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.0	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	1.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	1.0	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	1.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	3.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	1.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.0	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	2.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	1.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	1.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	2.0	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	2.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	3.6	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle
0.0	0.2	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	7.9	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.4	2.1	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.4	1.8	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.3	4.3	GO:0005243	gap junction channel activity(GO:0005243)
0.3	0.9	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3	1.4	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	1.2	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2	0.7	GO:0097677	STAT family protein binding(GO:0097677)
0.2	1.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.6	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.2	1.0	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2	5.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	0.7	GO:0038181	bile acid receptor activity(GO:0038181)
0.2	1.8	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.7	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.2	0.5	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	0.7	GO:0030305	heparanase activity(GO:0030305)
0.2	1.6	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2	1.4	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	0.4	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	1.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.6	GO:0008184	purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.1	0.3	GO:0033218	amide binding(GO:0033218)
0.1	1.7	GO:0038132	neuregulin binding(GO:0038132)
0.1	0.3	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1	1.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	1.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1	1.0	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.9	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.5	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	4.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0008859	exoribonuclease II activity(GO:0008859)
0.1	1.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1	0.3	GO:0008431	vitamin E binding(GO:0008431)
0.1	0.5	GO:0004645	phosphorylase activity(GO:0004645)
0.1	0.5	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.1	1.7	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.3	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.2	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	0.6	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.2	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	0.7	GO:0008430	selenium binding(GO:0008430)
0.1	0.8	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.4	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1	0.3	GO:0070404	NADH binding(GO:0070404)
0.1	0.2	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	1.0	GO:0031404	chloride ion binding(GO:0031404)
0.1	0.5	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.3	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	0.3	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	0.4	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1	5.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.5	GO:0050544	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	1.2	GO:0031489	myosin V binding(GO:0031489)
0.0	1.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.8	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0004040	amidase activity(GO:0004040)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.3	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	1.0	GO:0005112	Notch binding(GO:0005112)
0.0	0.7	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.4	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.4	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0033149	FFAT motif binding(GO:0033149)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.5	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	1.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.8	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.5	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.9	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0031877	somatostatin receptor binding(GO:0031877)
0.0	0.7	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0016247	channel regulator activity(GO:0016247)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	2.6	GO:0097110	scaffold protein binding(GO:0097110)
0.0	1.3	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0004730	pseudouridylate synthase activity(GO:0004730)
0.0	0.3	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	1.9	GO:0030276	clathrin binding(GO:0030276)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.5	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0	0.3	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	2.2	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.0	0.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.3	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.4	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.4	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0050294	steroid sulfotransferase activity(GO:0050294)
0.0	0.5	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.2	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.1	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.5	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.3	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.5	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0005174	CD40 receptor binding(GO:0005174)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	4.6	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.2	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.0	0.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.2	GO:1903136	cuprous ion binding(GO:1903136)
0.0	0.3	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0061659	ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.2	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.6	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.3	GO:0019905	syntaxin binding(GO:0019905)
0.0	5.5	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0070984	SET domain binding(GO:0070984)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	1.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.8	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	1.5	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.1	GO:0045179	apical cortex(GO:0045179)
0.2	2.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.2	1.4	GO:0043196	varicosity(GO:0043196)
0.1	0.4	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.5	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	0.4	GO:0005606	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1	0.6	GO:0061689	tricellular tight junction(GO:0061689)
0.1	0.8	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1	2.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.8	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	0.3	GO:0031251	PAN complex(GO:0031251)
0.1	0.9	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	2.7	GO:0030057	desmosome(GO:0030057)
0.1	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.3	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	1.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	1.5	GO:0001533	cornified envelope(GO:0001533)
0.1	0.6	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	1.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.3	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.2	GO:0070847	core mediator complex(GO:0070847)
0.0	0.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	3.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.7	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.3	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.3	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.3	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.4	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	2.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	2.4	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.2	GO:0033010	paranodal junction(GO:0033010)
0.0	0.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	1.5	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.8	GO:0014704	intercalated disc(GO:0014704)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.7	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.5	GO:0051233	spindle midzone(GO:0051233)
0.0	0.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.3	GO:0031082	BLOC complex(GO:0031082)
0.0	0.1	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.3	1.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.2	2.0	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.2	5.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	4.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	9.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.2	1.8	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	2.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	5.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	11.9	PID BCR 5PATHWAY	BCR signaling pathway
0.1	4.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	0.2	PID EPO PATHWAY	EPO signaling pathway
0.1	2.7	PID IGF1 PATHWAY	IGF1 pathway
0.1	0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	2.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	4.1	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	2.9	PID RAS PATHWAY	Regulation of Ras family activation
0.1	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.1	3.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	2.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	1.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	2.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	0.7	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.6	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	0.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	2.8	PID ATR PATHWAY	ATR signaling pathway
0.1	0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	1.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	3.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	1.6	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	1.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	1.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.3	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	1.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.0	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	1.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	2.1	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	2.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.6	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	3.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.6	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.2	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.2	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
2.0	ST GA13 PATHWAY	G alpha 13 Pathway
2.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
1.5	PID ILK PATHWAY	Integrin-linked kinase signaling
1.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
1.7	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
1.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.5	PID INSULIN PATHWAY	Insulin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	7.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	25.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.5	1.5	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.5	11.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4	3.9	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	9.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	3.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.2	4.8	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.2	3.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.2	1.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	4.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	6.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.2	2.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	3.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	7.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	9.5	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	5.2	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.6	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1	10.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	0.7	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	9.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	5.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	0.9	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	2.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	2.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	1.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.1	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.0	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.4	GO:0004122	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
1.1	4.3	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.8	2.5	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6	3.9	GO:0004793	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3	2.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.3	0.8	GO:0080130	phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3	1.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.3	0.8	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.2	0.6	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.2	1.1	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1	0.4	GO:0004819	glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.1	0.4	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	2.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	1.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	1.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	6.7	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.7	GO:0008483	transaminase activity(GO:0008483)
0.1	1.0	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	1.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	2.0	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.6	GO:0019789	SUMO transferase activity(GO:0019789) SUMO binding(GO:0032183)
0.0	0.3	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.3	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	1.8	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.2	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.6	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.7	GO:0070063	RNA polymerase binding(GO:0070063)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	7.0	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.2	4.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	6.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	1.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	3.9	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	3.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.6	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	1.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	1.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	3.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	2.0	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	3.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	2.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.0	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	2.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	2.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	2.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.0	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.7	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.8	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.8	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	11.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.2	4.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	15.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	29.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	6.4	PID BMP PATHWAY	BMP receptor signaling
0.1	4.9	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	2.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	3.7	ST GAQ PATHWAY	G alpha q Pathway
0.1	4.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	4.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	3.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.6	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	3.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	2.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.1	PID RHOA PATHWAY	RhoA signaling pathway
0.0	1.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.6	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	3.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	2.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:1904379	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.3	9.2	GO:0043101	purine-containing compound salvage(GO:0043101)
0.3	1.7	GO:0001692	histamine metabolic process(GO:0001692)
0.3	2.9	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.2	0.7	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.2	0.7	GO:0097359	UDP-glucosylation(GO:0097359)
0.2	0.7	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2	0.7	GO:0055048	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.2	0.9	GO:0044375	regulation of peroxisome size(GO:0044375)
0.2	0.6	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2	0.7	GO:0032053	ciliary basal body organization(GO:0032053)
0.1	0.6	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	1.4	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1	1.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1	0.6	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1	0.8	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.6	GO:2000843	testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1	0.6	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.1	0.6	GO:0046203	spermidine catabolic process(GO:0046203)
0.1	0.5	GO:0051344	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1	0.5	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1	1.0	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.6	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.5	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.1	0.8	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	1.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.5	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.4	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1	0.3	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1	0.7	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.3	GO:0001172	transcription, RNA-templated(GO:0001172)
0.1	0.4	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	0.3	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.1	1.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.7	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	1.5	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.1	0.5	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	0.3	GO:0021997	neural plate axis specification(GO:0021997)
0.1	0.8	GO:0032202	telomere assembly(GO:0032202)
0.1	0.2	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.2	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.1	0.7	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	0.4	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.4	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.5	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.1	1.3	GO:0035641	locomotory exploration behavior(GO:0035641)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.4	GO:0035900	response to isolation stress(GO:0035900)
0.1	0.2	GO:0019474	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1	1.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	1.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.2	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1	0.2	GO:0006382	adenosine to inosine editing(GO:0006382)
0.1	0.2	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.1	0.1	GO:0071392	cellular response to estrogen stimulus(GO:0071391) cellular response to estradiol stimulus(GO:0071392)
0.1	0.3	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.1	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.1	0.3	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.2	GO:0030242	pexophagy(GO:0030242)
0.0	0.5	GO:0015886	heme transport(GO:0015886)
0.0	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.2	GO:1904816	positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0	0.5	GO:0045008	depyrimidination(GO:0045008)
0.0	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.2	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0	0.1	GO:0018307	enzyme active site formation(GO:0018307)
0.0	0.3	GO:0032790	ribosome disassembly(GO:0032790)
0.0	1.0	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.0	1.0	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.4	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	0.3	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.2	GO:0071105	response to interleukin-11(GO:0071105)
0.0	1.3	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.5	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:0002752	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0	0.2	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.2	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	1.4	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	2.0	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.3	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.4	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.2	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	1.1	GO:1901998	toxin transport(GO:1901998)
0.0	0.0	GO:0071284	cellular response to lead ion(GO:0071284)
0.0	0.1	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.1	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.2	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0	0.4	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0051685	maintenance of ER location(GO:0051685)
0.0	0.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.3	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.0	0.3	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.4	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.6	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.4	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.1	GO:0060215	primitive hemopoiesis(GO:0060215)
0.0	0.2	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.1	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0	0.1	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.1	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.1	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.3	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.6	GO:0016579	protein deubiquitination(GO:0016579)
0.0	1.2	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	0.4	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.2	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.2	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.4	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.7	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.0	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0097480	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.5	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.3	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	0.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.3	GO:0030335	positive regulation of cell migration(GO:0030335)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	18.8	GO:0061518	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
2.9	8.6	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
2.1	6.2	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
1.4	4.3	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.3	5.2	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.7	3.5	GO:1905040	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.7	5.3	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.6	4.4	GO:0089700	protein kinase D signaling(GO:0089700)
0.6	1.8	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.6	2.8	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.5	1.6	GO:0034226	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.5	2.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.5	1.5	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.5	1.4	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.5	2.3	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4	7.2	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4	1.3	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.4	2.5	GO:0090131	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.4	7.7	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.4	1.1	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.4	3.2	GO:1903027	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.3	1.3	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3	8.5	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.3	1.2	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.3	0.9	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.3	0.9	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.3	2.3	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3	0.8	GO:0007412	axon target recognition(GO:0007412)
0.3	3.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2	0.5	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.2	3.0	GO:0035372	protein localization to microtubule(GO:0035372)
0.2	1.6	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.2	1.4	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2	1.1	GO:0030070	insulin processing(GO:0030070)
0.2	0.6	GO:2000360	positive regulation of female gonad development(GO:2000196) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2	2.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	0.9	GO:1903906	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2	1.1	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.2	0.7	GO:0014028	notochord formation(GO:0014028)
0.2	0.6	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2	0.5	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.2	0.5	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.2	0.5	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.4	GO:0032242	regulation of nucleoside transport(GO:0032242)
0.1	0.4	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1	0.6	GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1	0.6	GO:2000317	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1	2.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.8	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1	0.6	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	1.2	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	7.0	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.1	0.8	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.5	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	2.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	5.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.4	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1	1.8	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.6	GO:0006041	glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.1	3.4	GO:0015813	L-glutamate transport(GO:0015813)
0.1	0.8	GO:0001878	response to yeast(GO:0001878)
0.1	0.6	GO:2001183	negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1	1.9	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.4	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.8	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	0.3	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.3	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1	0.3	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	2.1	GO:0003334	keratinocyte development(GO:0003334)
0.1	1.7	GO:0051764	actin crosslink formation(GO:0051764)
0.1	0.3	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0090135	B-1 B cell homeostasis(GO:0001922) actin filament branching(GO:0090135)
0.1	1.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	1.3	GO:0016540	protein autoprocessing(GO:0016540)
0.1	0.8	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	1.8	GO:0007567	parturition(GO:0007567)
0.1	0.4	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	1.6	GO:0048266	behavioral response to pain(GO:0048266)
0.1	0.2	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.9	GO:0090091	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) positive regulation of extracellular matrix disassembly(GO:0090091)
0.1	0.4	GO:2000784	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1	0.5	GO:0008218	bioluminescence(GO:0008218)
0.1	1.5	GO:0046697	decidualization(GO:0046697)
0.1	0.2	GO:0046521	sphingoid catabolic process(GO:0046521)
0.1	0.3	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.5	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.5	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1	1.2	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.3	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.4	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1	0.3	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.4	GO:0031642	negative regulation of myelination(GO:0031642)
0.1	0.5	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1	0.2	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.8	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.2	GO:0060620	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.1	0.9	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.3	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1	1.4	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.2	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.1	0.7	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.1	0.2	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.1	0.9	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.5	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:1904647	response to rotenone(GO:1904647)
0.0	0.2	GO:0007538	primary sex determination(GO:0007538)
0.0	1.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.3	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0	0.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.2	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:0038178	complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0	0.2	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.0	0.1	GO:0006014	D-ribose metabolic process(GO:0006014)
0.0	1.4	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.7	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0	0.2	GO:0010748	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	1.8	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.3	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.5	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.3	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.2	GO:0009624	response to nematode(GO:0009624)
0.0	0.1	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.0	0.2	GO:0019532	oxalate transport(GO:0019532)
0.0	0.3	GO:0035799	ureter maturation(GO:0035799)
0.0	0.9	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	0.4	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.4	GO:0006559	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	2.4	GO:0006968	cellular defense response(GO:0006968)
0.0	0.3	GO:2001234	negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	3.0	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.1	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	1.0	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.1	GO:0039516	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0	0.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.2	GO:0099612	protein localization to axon(GO:0099612)
0.0	0.3	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	1.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.2	GO:0070914	UV-damage excision repair(GO:0070914)
0.0	0.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.3	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.5	GO:0006825	copper ion transport(GO:0006825)
0.0	0.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.4	GO:0030220	platelet formation(GO:0030220)
0.0	0.9	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.3	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.2	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.0	0.2	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.3	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.2	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.3	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.5	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.3	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.1	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.3	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.1	GO:0071321	cellular response to cGMP(GO:0071321)
0.0	0.6	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.0	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.6	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	1.7	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	0.1	GO:0010454	negative regulation of cell fate commitment(GO:0010454)
0.0	0.2	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.4	GO:0042073	intraciliary transport(GO:0042073)
0.0	0.3	GO:0097186	amelogenesis(GO:0097186)
0.0	0.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.1	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.6	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	0.7	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.2	GO:0001771	immunological synapse formation(GO:0001771)
0.0	0.7	GO:0061053	somite development(GO:0061053)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0061303	cornea development in camera-type eye(GO:0061303)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.3	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.2	5.7	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	14.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.7	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	1.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.4	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	2.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.3	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.8	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	1.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.7	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	1.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.9	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.7	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.5	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	1.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	2.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	2.4	REACTOME MITOTIC M M G1 PHASES	Genes involved in Mitotic M-M/G1 phases
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	1.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.7	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.7	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	3.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.6	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	2.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	3.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	0.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	3.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	2.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	2.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	5.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	1.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	1.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	2.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.9	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.9	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	3.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.8	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	1.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	24.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.4	17.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.3	0.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.2	7.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.2	9.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	12.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	38.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	10.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	11.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	0.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	5.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	5.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	4.6	PID ALK1 PATHWAY	ALK1 signaling events
0.2	3.8	PID ARF 3PATHWAY	Arf1 pathway
0.2	9.4	PID BMP PATHWAY	BMP receptor signaling
0.2	8.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	2.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	2.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	2.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.1	7.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	35.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	5.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	7.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	11.4	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	1.5	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	4.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	1.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	3.2	PID IGF1 PATHWAY	IGF1 pathway
0.1	1.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	2.7	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	3.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	2.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	5.2	PID PLK1 PATHWAY	PLK1 signaling events
0.1	1.7	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	2.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	0.8	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	1.8	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	3.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	2.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	1.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	2.5	PID AURORA B PATHWAY	Aurora B signaling
0.1	2.3	PID AURORA A PATHWAY	Aurora A signaling
0.1	1.4	PID P73PATHWAY	p73 transcription factor network
0.1	0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	1.8	PID FOXO PATHWAY	FoxO family signaling
0.1	1.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	3.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	2.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	1.4	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	1.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.8	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.3	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	1.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.0	11.9	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
1.5	4.5	GO:0035501	MH1 domain binding(GO:0035501)
1.3	7.7	GO:1990254	keratin filament binding(GO:1990254)
1.3	3.8	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.9	6.4	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.8	6.5	GO:0005534	galactose binding(GO:0005534)
0.8	3.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.7	14.9	GO:0051787	misfolded protein binding(GO:0051787)
0.7	8.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.7	2.1	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.6	2.3	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.6	9.1	GO:0045499	chemorepellent activity(GO:0045499)
0.4	1.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.4	3.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.4	4.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.4	10.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.4	1.1	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3	2.8	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.3	3.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.3	1.1	GO:0042954	apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.2	1.5	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2	2.7	GO:0045159	myosin II binding(GO:0045159)
0.2	2.5	GO:0050786	RAGE receptor binding(GO:0050786)
0.2	2.1	GO:0031013	troponin I binding(GO:0031013)
0.2	1.3	GO:0071253	connexin binding(GO:0071253)
0.2	0.7	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2	6.8	GO:0042056	chemoattractant activity(GO:0042056)
0.2	0.5	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2	0.5	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2	0.6	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1	3.7	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1	0.6	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.1	3.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.4	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	0.4	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.1	1.4	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.5	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	15.7	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	0.7	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	2.9	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	2.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	2.8	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	2.6	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	5.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.4	GO:0015265	urea channel activity(GO:0015265)
0.1	0.8	GO:0036122	BMP binding(GO:0036122)
0.1	0.5	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	1.5	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.8	GO:0032357	oxidized purine DNA binding(GO:0032357)
0.1	0.3	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	8.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.9	GO:0008430	selenium binding(GO:0008430)
0.1	0.8	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1	0.2	GO:0050610	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1	1.0	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	2.0	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	0.8	GO:0070569	uridylyltransferase activity(GO:0070569)
0.1	0.5	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	0.3	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.5	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.2	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	2.2	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.6	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.0	4.0	GO:0017022	myosin binding(GO:0017022)
0.0	0.4	GO:0001849	complement component C1q binding(GO:0001849)
0.0	2.1	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	1.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	2.1	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.1	GO:0008940	nitrate reductase activity(GO:0008940)
0.0	0.3	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.5	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.8	GO:0005123	death receptor binding(GO:0005123)
0.0	3.4	GO:0008201	heparin binding(GO:0008201)
0.0	0.6	GO:0043236	laminin binding(GO:0043236)
0.0	0.7	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	2.5	GO:0019838	growth factor binding(GO:0019838)
0.0	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.7	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	1.6	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.6	GO:0032813	tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0	0.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.6	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	1.0	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.3	GO:0000993	RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.5	3.3	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.4	1.4	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3	2.1	GO:0042610	CD8 receptor binding(GO:0042610)
0.3	0.7	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.3	1.3	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.3	1.2	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3	0.3	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.3	3.3	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	12.3	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.2	2.7	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	0.6	GO:0003826	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2	2.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	1.3	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.2	0.7	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.2	0.7	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.2	0.6	GO:0004348	glucosylceramidase activity(GO:0004348)
0.2	0.5	GO:0004947	bradykinin receptor activity(GO:0004947)
0.2	0.9	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1	1.2	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	0.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	4.1	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.7	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.8	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.5	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.1	0.5	GO:0019770	IgG receptor activity(GO:0019770)
0.1	0.5	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.1	0.5	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	2.1	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.8	GO:0001515	opioid peptide activity(GO:0001515)
0.1	3.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	1.6	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	1.8	GO:0031996	thioesterase binding(GO:0031996)
0.1	1.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1	0.7	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	0.6	GO:0043532	angiostatin binding(GO:0043532)
0.1	2.1	GO:0043495	protein anchor(GO:0043495)
0.1	0.4	GO:0070330	aromatase activity(GO:0070330)
0.1	0.6	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	1.1	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1	0.6	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.6	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.1	0.2	GO:0008200	ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.1	0.4	GO:0061714	folic acid receptor activity(GO:0061714)
0.1	0.4	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.6	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.3	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.7	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.3	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1	0.4	GO:0008410	CoA-transferase activity(GO:0008410)
0.1	1.4	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	0.3	GO:0050135	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.9	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.5	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.3	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.9	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.2	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.1	0.2	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.2	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	0.5	GO:0017018	myosin phosphatase activity(GO:0017018)
0.1	0.7	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.4	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	2.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	2.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.5	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.8	GO:0042731	PH domain binding(GO:0042731)
0.1	0.3	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	0.4	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.4	GO:0051373	FATZ binding(GO:0051373)
0.1	10.3	GO:0003823	antigen binding(GO:0003823)
0.1	1.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.6	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.4	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.1	0.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.7	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.5	GO:0016015	morphogen activity(GO:0016015)
0.1	0.3	GO:0097001	ceramide binding(GO:0097001)
0.1	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.1	0.3	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.1	0.2	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	0.1	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	1.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	0.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.8	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	0.4	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.2	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.3	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	0.1	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	1.9	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.2	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	0.4	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.2	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	0.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.1	GO:0051870	methotrexate binding(GO:0051870)
0.1	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.6	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.2	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.8	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.1	GO:0046332	SMAD binding(GO:0046332)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.2	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1	0.6	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.4	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.1	0.3	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.2	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1	0.4	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1	0.2	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	0.3	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.1	0.1	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	0.2	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	0.1	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.1	0.3	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	0.7	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.7	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.9	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0031716	calcitonin receptor binding(GO:0031716)
0.0	0.1	GO:0003883	CTP synthase activity(GO:0003883)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	1.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.3	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.2	GO:0046538	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	1.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0	0.3	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0	0.2	GO:0031208	POZ domain binding(GO:0031208)
0.0	0.9	GO:0048018	receptor agonist activity(GO:0048018)
0.0	1.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.3	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.8	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.3	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	3.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.2	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0016979	lipoate-protein ligase activity(GO:0016979)
0.0	0.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.4	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.3	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.2	GO:0004979	beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0	0.1	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0	0.0	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.2	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0	0.2	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.2	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.1	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.2	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0	0.1	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0	0.0	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.4	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	0.3	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	1.8	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.0	0.4	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	4.3	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0	0.5	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0070260	tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0	0.2	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0	0.2	GO:0004882	androgen receptor activity(GO:0004882)
0.0	0.2	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0016730	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0	0.2	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.0	0.9	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.3	GO:0089720	caspase binding(GO:0089720)
0.0	0.5	GO:0043295	glutathione binding(GO:0043295)
0.0	0.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	1.4	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0	0.2	GO:0016820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0	0.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.0	0.2	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.4	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.3	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.1	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0072510	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0	0.3	GO:0043047	single-stranded telomeric DNA binding(GO:0043047)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.4	GO:0070513	death domain binding(GO:0070513)
0.0	0.3	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.3	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.0	0.1	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.1	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0	0.1	GO:0004074	biliverdin reductase activity(GO:0004074)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	1.1	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.0	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.2	GO:0036122	BMP binding(GO:0036122)
0.0	1.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.4	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.0	0.5	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.0	0.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0016918	retinal binding(GO:0016918)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	1.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0045125	sphingosine-1-phosphate receptor activity(GO:0038036) bioactive lipid receptor activity(GO:0045125)
0.0	0.6	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.0	0.7	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.5	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0	0.3	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.0	0.0	GO:0016595	glutamate binding(GO:0016595)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.2	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0032406	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	1.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.0	0.2	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.2	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.0	0.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.0	0.1	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0008443	phosphofructokinase activity(GO:0008443)
0.0	0.1	GO:1904047	S-adenosyl-L-methionine binding(GO:1904047)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.6	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.0	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.0	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.2	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.1	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.0	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.0	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0016504	peptidase activator activity(GO:0016504)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.0	GO:0015616	DNA translocase activity(GO:0015616)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0016499	orexin receptor activity(GO:0016499)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	1.6	GO:0017124	SH3 domain binding(GO:0017124)
0.0	1.7	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.1	GO:1901611	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.0	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0	0.1	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0	0.0	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.0	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.1	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.0	0.0	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.0	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	0.0	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.0	0.1	GO:0017160	Ral GTPase binding(GO:0017160)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.7	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.8	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.2	9.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	0.6	PID ALK2 PATHWAY	ALK2 signaling events
0.1	2.8	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	2.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	9.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	1.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	1.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	1.8	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	5.6	PID NOTCH PATHWAY	Notch signaling pathway
0.1	6.6	PID E2F PATHWAY	E2F transcription factor network
0.1	3.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	2.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	1.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	5.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	3.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	1.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	1.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	2.1	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	2.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	0.4	PID FOXO PATHWAY	FoxO family signaling
0.0	2.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.6	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	2.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	2.8	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	2.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	2.7	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.1	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.5	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.7	PID ATR PATHWAY	ATR signaling pathway
0.0	0.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.3	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.2	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.4	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.3	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	23.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.6	15.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.6	35.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.4	11.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	8.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	4.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.3	4.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	0.8	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	4.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	5.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	4.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	0.3	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1	2.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	2.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	3.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	3.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.2	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.1	2.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.9	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	3.0	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	1.5	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.1	2.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	3.5	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	0.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	2.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.3	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	2.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	4.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	2.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	2.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	3.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	1.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	1.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.9	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.9	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	7.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	9.2	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	1.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	2.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	1.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.3	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.6	REACTOME SIGNALING BY NOTCH	Genes involved in Signaling by NOTCH
0.0	2.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	1.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.3	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	11.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	2.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	3.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	7.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	3.9	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	4.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	0.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	6.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	2.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.7	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	1.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	2.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.0	0.3	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.0	0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	1.1	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.1	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	2.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
1.2	28.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.1	59.9	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.0	18.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.9	43.6	NABA COLLAGENS	Genes encoding collagen proteins
0.9	24.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.8	37.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.8	21.8	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.8	57.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.8	1.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7	42.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.7	4.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.7	1.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.6	10.8	PID ALK1 PATHWAY	ALK1 signaling events
0.6	24.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.6	23.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.6	126.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.6	19.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.6	43.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.5	34.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.5	19.8	PID IGF1 PATHWAY	IGF1 pathway
0.5	22.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.5	9.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.5	8.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.4	1.7	ST ADRENERGIC	Adrenergic Pathway
0.4	14.8	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.4	10.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.4	14.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.4	3.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	94.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4	9.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.4	13.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.3	3.8	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.3	2.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.3	14.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	23.8	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.3	5.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.3	19.0	PID BMP PATHWAY	BMP receptor signaling
0.3	5.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	3.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	2.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.3	2.6	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.3	5.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.3	9.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.3	16.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.3	8.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.3	3.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.3	43.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	8.5	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.3	3.6	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	1.7	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.2	9.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.2	12.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	3.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.2	3.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	1.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.2	3.5	PID INSULIN PATHWAY	Insulin Pathway
0.2	0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	1.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	4.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	3.7	PID ARF 3PATHWAY	Arf1 pathway
0.2	5.0	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	12.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	2.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.2	6.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	2.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2	1.6	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.2	0.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	3.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	1.6	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	1.0	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	3.4	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.1	9.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	9.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	1.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	3.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	1.5	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	4.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	3.3	PID FGF PATHWAY	FGF signaling pathway
0.1	4.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	1.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	2.6	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	2.9	PID CDC42 PATHWAY	CDC42 signaling events
0.1	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	24.4	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.1	1.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	1.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	2.6	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	0.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.2	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	9.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.3	6.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.3	8.3	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.3	8.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	10.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	2.6	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.2	6.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	0.9	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.2	5.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2	0.4	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.2	3.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	4.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	0.2	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.2	11.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2	9.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	2.9	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.2	1.5	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2	3.0	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	3.6	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	1.5	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.2	6.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	2.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	2.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	2.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.9	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	6.0	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	5.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	2.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	3.1	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	1.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.4	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	5.6	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.1	2.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	0.2	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.1	2.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	2.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	0.6	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	2.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.1	0.7	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	4.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.0	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	2.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	0.8	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	0.1	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.1	1.3	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	2.0	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	3.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	4.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	0.3	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.1	1.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	2.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	2.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	1.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	0.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	0.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.4	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	0.2	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.1	1.0	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1	2.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	0.5	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.1	0.2	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	1.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	1.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	7.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	1.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	2.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	3.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	6.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.7	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	4.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.8	REACTOME TRANSLATION	Genes involved in Translation
0.0	1.6	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	1.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	3.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.6	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.7	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	Genes involved in Phospholipase C-mediated cascade
0.0	0.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	2.2	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	2.3	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	0.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.7	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	3.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	2.2	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.4	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.2	REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR	Genes involved in Downstream signaling of activated FGFR
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	1.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.2	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
1.6	6.3	GO:0071001	U4/U6 snRNP(GO:0071001)
1.4	4.1	GO:0032302	MutSbeta complex(GO:0032302)
1.2	4.8	GO:0044611	nuclear pore inner ring(GO:0044611)
1.2	4.8	GO:0033186	CAF-1 complex(GO:0033186)
1.2	4.8	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.2	3.5	GO:0005873	plus-end kinesin complex(GO:0005873)
1.2	4.7	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.0	5.0	GO:0032021	NELF complex(GO:0032021)
1.0	3.9	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
1.0	12.6	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.0	3.9	GO:0000799	nuclear condensin complex(GO:0000799)
0.9	7.2	GO:0042382	paraspeckles(GO:0042382)
0.8	3.3	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.8	2.3	GO:1990423	RZZ complex(GO:1990423)
0.8	5.4	GO:0046581	intercellular canaliculus(GO:0046581)
0.8	3.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.8	3.8	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.7	20.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.7	2.2	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.7	2.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.7	6.4	GO:0005638	lamin filament(GO:0005638)
0.7	4.8	GO:0001520	outer dense fiber(GO:0001520)
0.7	1.3	GO:0031213	RSF complex(GO:0031213)
0.6	3.2	GO:0016589	NURF complex(GO:0016589)
0.6	2.6	GO:0000798	nuclear cohesin complex(GO:0000798)
0.6	3.9	GO:0000796	condensin complex(GO:0000796)
0.6	5.1	GO:0070552	BRISC complex(GO:0070552)
0.6	1.9	GO:0070939	Dsl1p complex(GO:0070939)
0.6	1.9	GO:0034455	t-UTP complex(GO:0034455)
0.6	4.4	GO:0016272	prefoldin complex(GO:0016272)
0.6	6.8	GO:0044666	MLL3/4 complex(GO:0044666)
0.6	4.1	GO:0061700	GATOR2 complex(GO:0061700)
0.6	6.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.6	4.0	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5	1.6	GO:0031262	Ndc80 complex(GO:0031262)
0.5	3.7	GO:0031415	NatA complex(GO:0031415)
0.5	1.6	GO:0001740	Barr body(GO:0001740)
0.5	3.6	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.5	6.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.5	2.3	GO:0034457	Mpp10 complex(GO:0034457)
0.5	10.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.4	4.9	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.4	3.0	GO:0060091	kinocilium(GO:0060091)
0.4	1.3	GO:0098536	deuterosome(GO:0098536)
0.4	3.4	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4	2.0	GO:0035061	interchromatin granule(GO:0035061)
0.4	2.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.4	6.8	GO:0000812	Swr1 complex(GO:0000812)
0.4	7.5	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.4	2.7	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.4	16.1	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.4	4.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.4	1.8	GO:0070470	plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.4	3.9	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.3	1.0	GO:0019034	viral replication complex(GO:0019034)
0.3	1.7	GO:0089701	U2AF(GO:0089701)
0.3	1.7	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.3	6.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3	3.7	GO:0042555	MCM complex(GO:0042555)
0.3	1.6	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.3	2.9	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.3	3.8	GO:0005686	U2 snRNP(GO:0005686)
0.3	1.9	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.3	5.6	GO:0034709	methylosome(GO:0034709)
0.3	4.9	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.3	5.1	GO:0005682	U5 snRNP(GO:0005682)
0.3	0.9	GO:0070557	PCNA-p21 complex(GO:0070557)
0.3	1.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3	0.9	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.3	5.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.3	1.5	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3	5.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.3	2.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3	1.9	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.3	1.3	GO:0044530	supraspliceosomal complex(GO:0044530)
0.3	3.9	GO:0000346	transcription export complex(GO:0000346)
0.2	5.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	0.7	GO:1990635	proximal dendrite(GO:1990635)
0.2	1.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	3.9	GO:0000178	exosome (RNase complex)(GO:0000178)
0.2	1.7	GO:0030870	Mre11 complex(GO:0030870)
0.2	0.7	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.2	3.7	GO:0097346	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.2	2.5	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.2	1.8	GO:0042575	DNA polymerase complex(GO:0042575)
0.2	3.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.2	1.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.2	2.9	GO:0035253	ciliary rootlet(GO:0035253)
0.2	1.6	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
0.2	1.6	GO:0019815	B cell receptor complex(GO:0019815)
0.2	1.3	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.2	4.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2	4.1	GO:0010369	chromocenter(GO:0010369)
0.2	3.0	GO:0097431	mitotic spindle pole(GO:0097431)
0.2	1.3	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2	1.3	GO:0005802	trans-Golgi network(GO:0005802)
0.2	0.4	GO:0030125	clathrin vesicle coat(GO:0030125)
0.2	5.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2	3.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2	2.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.2	1.5	GO:0097165	nuclear stress granule(GO:0097165)
0.2	12.2	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2	1.4	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.2	1.8	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.2	9.4	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2	3.7	GO:0001891	phagocytic cup(GO:0001891)
0.2	1.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.2	6.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.2	2.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.2	1.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.2	5.4	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.2	1.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.2	1.0	GO:0030905	retromer, tubulation complex(GO:0030905)
0.2	1.4	GO:0000322	storage vacuole(GO:0000322)
0.2	2.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	1.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2	0.5	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.2	1.5	GO:0044194	cytolytic granule(GO:0044194)
0.2	2.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2	0.3	GO:0001940	male pronucleus(GO:0001940)
0.2	1.9	GO:0017119	Golgi transport complex(GO:0017119)
0.2	2.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.2	3.5	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.2	1.8	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.2	1.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2	1.8	GO:0030008	TRAPP complex(GO:0030008)
0.1	1.3	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.1	1.9	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	5.5	GO:0016592	mediator complex(GO:0016592)
0.1	2.3	GO:0000242	pericentriolar material(GO:0000242)
0.1	2.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	2.6	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1	4.1	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	1.0	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.6	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	1.0	GO:0072487	MSL complex(GO:0072487)
0.1	10.3	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.1	1.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	0.7	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	1.2	GO:0071439	clathrin complex(GO:0071439)
0.1	3.9	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	1.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	1.1	GO:0032039	integrator complex(GO:0032039)
0.1	0.4	GO:0044609	DBIRD complex(GO:0044609)
0.1	1.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	4.6	GO:0031519	PcG protein complex(GO:0031519)
0.1	6.8	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.1	17.1	GO:0005681	spliceosomal complex(GO:0005681)
0.1	1.7	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	3.8	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	0.5	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1	0.2	GO:0001939	female pronucleus(GO:0001939)
0.1	1.9	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	7.7	GO:0005643	nuclear pore(GO:0005643)
0.1	10.5	GO:0016605	PML body(GO:0016605)
0.1	0.8	GO:0097433	dense body(GO:0097433)
0.1	0.4	GO:0000793	condensed chromosome(GO:0000793)
0.1	0.4	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.9	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	6.3	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1	26.3	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.1	0.9	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	0.4	GO:0051286	cell tip(GO:0051286)
0.1	0.3	GO:0071564	SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.1	15.5	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.1	0.6	GO:0042788	polysomal ribosome(GO:0042788)
0.1	5.0	GO:0031526	brush border membrane(GO:0031526)
0.1	21.1	GO:0005759	mitochondrial matrix(GO:0005759)
0.1	0.5	GO:0031931	TORC1 complex(GO:0031931)
0.1	0.8	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	0.8	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.5	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	1.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	4.9	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	0.7	GO:0090543	Flemming body(GO:0090543)
0.1	9.3	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	0.5	GO:0005787	signal peptidase complex(GO:0005787)
0.1	2.3	GO:0005844	polysome(GO:0005844)
0.1	1.3	GO:0000795	synaptonemal complex(GO:0000795)
0.1	0.8	GO:0000781	chromosome, telomeric region(GO:0000781)
0.1	0.6	GO:0030027	lamellipodium(GO:0030027)
0.1	2.5	GO:0005876	spindle microtubule(GO:0005876)
0.1	4.6	GO:0005814	centriole(GO:0005814)
0.1	0.5	GO:0070938	contractile ring(GO:0070938)
0.1	4.8	GO:0005667	transcription factor complex(GO:0005667)
0.1	0.1	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.1	2.3	GO:0072686	mitotic spindle(GO:0072686)
0.1	12.9	GO:0000790	nuclear chromatin(GO:0000790)
0.1	0.2	GO:0030686	90S preribosome(GO:0030686)
0.1	0.2	GO:0030314	junctional membrane complex(GO:0030314)
0.1	0.1	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.5	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.4	GO:0005869	dynactin complex(GO:0005869)
0.0	2.8	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	9.1	GO:0005813	centrosome(GO:0005813)
0.0	0.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	2.3	GO:0000502	proteasome complex(GO:0000502)
0.0	0.7	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.4	GO:1990909	catenin complex(GO:0016342) Wnt signalosome(GO:1990909)
0.0	0.2	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.0	2.7	GO:0000922	spindle pole(GO:0000922)
0.0	1.0	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	7.2	GO:0005840	ribosome(GO:0005840)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.6	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.5	GO:0031209	SCAR complex(GO:0031209)
0.0	1.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	6.2	GO:0031966	mitochondrial membrane(GO:0031966)
0.0	1.2	GO:0015030	Cajal body(GO:0015030)
0.0	1.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	4.1	GO:0000785	chromatin(GO:0000785)
0.0	0.4	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	1.6	GO:0031201	SNARE complex(GO:0031201)
0.0	1.9	GO:0016363	nuclear matrix(GO:0016363)
0.0	75.3	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.2	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.1	GO:0030684	preribosome(GO:0030684)
0.0	0.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.3	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	3.7	GO:0031965	nuclear membrane(GO:0031965)
0.0	1.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	1.5	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.5	GO:0005929	cilium(GO:0005929)
0.0	0.7	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.0	GO:0018444	translation release factor complex(GO:0018444)
0.0	0.6	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.3	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	2.1	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	1.6	GO:0005938	cell cortex(GO:0005938)
0.0	0.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	23.5	GO:0031014	troponin T binding(GO:0031014)
1.4	5.8	GO:0004074	biliverdin reductase activity(GO:0004074)
1.2	3.5	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
1.0	8.1	GO:0005497	androgen binding(GO:0005497)
1.0	3.0	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
1.0	3.0	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
1.0	3.9	GO:1904408	dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.9	5.6	GO:1990254	keratin filament binding(GO:1990254)
0.9	3.7	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.9	9.5	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.9	10.2	GO:1990459	transferrin receptor binding(GO:1990459)
0.8	4.8	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.8	5.4	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.7	2.2	GO:0030984	kininogen binding(GO:0030984)
0.7	2.8	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.7	2.0	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.7	4.6	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.7	2.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.7	3.9	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.6	5.1	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.6	3.8	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6	3.1	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.6	1.9	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.6	0.6	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.6	0.6	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.6	2.4	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.6	1.8	GO:0032090	Pyrin domain binding(GO:0032090)
0.6	3.0	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.6	3.5	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.6	3.5	GO:0005499	vitamin D binding(GO:0005499)
0.6	1.7	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6	7.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.6	5.0	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5	3.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.5	2.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.5	2.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.5	1.6	GO:0004603	phenylethanolamine N-methyltransferase activity(GO:0004603)
0.5	2.7	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5	2.1	GO:0032143	single thymine insertion binding(GO:0032143)
0.5	1.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.5	1.5	GO:0070984	SET domain binding(GO:0070984)
0.5	7.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5	1.5	GO:0003883	CTP synthase activity(GO:0003883)
0.5	4.3	GO:0032051	clathrin light chain binding(GO:0032051)
0.5	1.4	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.5	2.3	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.5	1.4	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.5	0.5	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.5	1.4	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.5	2.3	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.5	1.4	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.5	1.4	GO:0004730	pseudouridylate synthase activity(GO:0004730)
0.5	2.3	GO:0070026	nitric oxide binding(GO:0070026)
0.4	2.7	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.4	1.3	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4	0.9	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.4	1.3	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.4	1.3	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.4	1.3	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.4	1.7	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.4	1.6	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.4	2.1	GO:0050815	phosphoserine binding(GO:0050815)
0.4	7.8	GO:0044548	S100 protein binding(GO:0044548)
0.4	1.2	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.4	21.9	GO:0017080	sodium channel regulator activity(GO:0017080)
0.4	0.4	GO:0016530	metallochaperone activity(GO:0016530)
0.4	1.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.4	1.6	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.4	1.2	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.4	1.2	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.4	0.4	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.4	0.4	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.4	1.5	GO:0008431	vitamin E binding(GO:0008431)
0.4	1.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.4	2.3	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.4	0.4	GO:0032142	single guanine insertion binding(GO:0032142)
0.4	1.1	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.4	1.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.4	3.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.4	1.8	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.4	2.6	GO:0015288	porin activity(GO:0015288)
0.4	0.4	GO:0031491	nucleosome binding(GO:0031491)
0.4	0.4	GO:0001222	transcription corepressor binding(GO:0001222)
0.4	1.4	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4	2.1	GO:0052655	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4	4.2	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.4	5.6	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.4	2.1	GO:1903135	cupric ion binding(GO:1903135)
0.3	9.8	GO:0030506	ankyrin binding(GO:0030506)
0.3	1.4	GO:0015254	glycerol channel activity(GO:0015254)
0.3	1.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3	3.4	GO:0030911	TPR domain binding(GO:0030911)
0.3	1.0	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.3	2.0	GO:0042296	ISG15 transferase activity(GO:0042296)
0.3	1.3	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
0.3	1.6	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.3	1.0	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.3	2.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.3	6.2	GO:0005112	Notch binding(GO:0005112)
0.3	1.0	GO:0004766	spermidine synthase activity(GO:0004766)
0.3	1.0	GO:0032767	copper-dependent protein binding(GO:0032767)
0.3	1.6	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.3	2.5	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.3	0.9	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.3	2.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.3	1.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3	1.5	GO:0030348	syntaxin-3 binding(GO:0030348)
0.3	1.8	GO:0019776	Atg8 ligase activity(GO:0019776)
0.3	0.9	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.3	1.5	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.3	3.6	GO:0031386	protein tag(GO:0031386)
0.3	3.0	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.3	0.9	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.3	0.9	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.3	3.0	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.3	1.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.3	3.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.3	1.2	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.3	0.6	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.3	2.1	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.3	0.9	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.3	2.0	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.3	2.9	GO:0045294	alpha-catenin binding(GO:0045294)
0.3	0.9	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.3	3.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.3	2.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.3	1.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.3	1.7	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	0.9	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.3	11.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3	1.1	GO:0004132	dCMP deaminase activity(GO:0004132)
0.3	0.8	GO:0032427	GBD domain binding(GO:0032427)
0.3	0.6	GO:0052843	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.3	3.9	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3	1.4	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.3	1.6	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.3	4.9	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3	2.2	GO:0004111	creatine kinase activity(GO:0004111)
0.3	0.8	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3	0.3	GO:0001515	opioid peptide activity(GO:0001515)
0.3	0.8	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3	1.6	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.3	2.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.3	2.6	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.3	1.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.3	0.8	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	0.8	GO:0043398	HLH domain binding(GO:0043398)
0.3	4.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2	3.5	GO:0031489	myosin V binding(GO:0031489)
0.2	0.7	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2	2.2	GO:0004969	histamine receptor activity(GO:0004969)
0.2	0.7	GO:0033149	FFAT motif binding(GO:0033149)
0.2	2.0	GO:0004565	beta-galactosidase activity(GO:0004565)
0.2	0.2	GO:0002060	purine nucleobase binding(GO:0002060)
0.2	5.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2	0.2	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.2	4.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.2	0.7	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.2	2.4	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2	0.7	GO:0035671	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2	0.9	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.2	0.7	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.2	3.3	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2	0.5	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.2	0.7	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.2	18.0	GO:0019003	GDP binding(GO:0019003)
0.2	0.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.2	0.7	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2	1.4	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.2	1.4	GO:0004473	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.2	3.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	2.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.2	0.9	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.2	1.8	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2	10.2	GO:0050699	WW domain binding(GO:0050699)
0.2	3.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	1.6	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.2	1.3	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.2	0.7	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.2	1.3	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	2.6	GO:0089720	caspase binding(GO:0089720)
0.2	0.7	GO:0031877	somatostatin receptor binding(GO:0031877)
0.2	0.9	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2	1.5	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2	1.7	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2	0.9	GO:0017089	glycolipid transporter activity(GO:0017089)
0.2	5.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.2	2.1	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.2	0.8	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.2	0.8	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2	0.8	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.2	1.0	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.2	0.6	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.2	0.6	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2	1.7	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.2	0.6	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.2	1.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.2	0.8	GO:0016880	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2	1.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	1.4	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.2	1.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.2	3.6	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.2	5.2	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.2	0.6	GO:0034511	U3 snoRNA binding(GO:0034511)
0.2	2.2	GO:0005243	gap junction channel activity(GO:0005243)
0.2	1.4	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.2	1.8	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	2.6	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	0.6	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	3.5	GO:0001054	RNA polymerase I activity(GO:0001054)
0.2	0.8	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2	0.6	GO:0050693	LBD domain binding(GO:0050693)
0.2	1.4	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2	0.6	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2	1.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.2	2.5	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.2	3.6	GO:0097602	cullin family protein binding(GO:0097602)
0.2	3.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.2	0.4	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.2	1.7	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	3.6	GO:0017070	U6 snRNA binding(GO:0017070)
0.2	2.8	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.2	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.2	3.2	GO:0031005	filamin binding(GO:0031005)
0.2	1.7	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2	0.6	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.2	0.7	GO:0004743	pyruvate kinase activity(GO:0004743)
0.2	0.2	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.2	0.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	2.9	GO:0019992	diacylglycerol binding(GO:0019992)
0.2	8.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.2	1.5	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	0.5	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.2	0.4	GO:0016882	cyclo-ligase activity(GO:0016882)
0.2	3.3	GO:0008198	ferrous iron binding(GO:0008198)
0.2	3.4	GO:0070300	phosphatidic acid binding(GO:0070300)
0.2	0.4	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.2	0.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.2	0.9	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.2	1.6	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.2	6.8	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.2	3.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	1.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	0.5	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2	3.0	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.2	5.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	1.0	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	0.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2	1.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.2	1.0	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.2	1.0	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.2	1.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	3.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	2.8	GO:0048018	receptor agonist activity(GO:0048018)
0.2	2.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	1.5	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.2	0.6	GO:0051373	FATZ binding(GO:0051373)
0.2	0.6	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.2	0.8	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.2	0.5	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2	1.9	GO:0030957	Tat protein binding(GO:0030957)
0.2	0.3	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2	0.5	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	0.2	GO:0030366	molybdopterin synthase activity(GO:0030366)
0.2	0.9	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2	0.6	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.2	1.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.2	1.7	GO:0004407	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2	3.4	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.2	0.6	GO:0043208	glycosphingolipid binding(GO:0043208)
0.2	0.3	GO:0032135	DNA insertion or deletion binding(GO:0032135)
0.2	0.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2	0.3	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.2	0.2	GO:0000405	bubble DNA binding(GO:0000405)
0.2	2.0	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.2	2.3	GO:0009881	photoreceptor activity(GO:0009881)
0.2	1.8	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.2	0.5	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.2	1.8	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2	4.2	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.2	1.1	GO:0043621	protein self-association(GO:0043621)
0.2	1.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	1.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	2.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	4.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.7	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	2.2	GO:0016208	AMP binding(GO:0016208)
0.1	0.9	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	2.4	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.1	1.0	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	0.4	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1	0.3	GO:0008494	translation activator activity(GO:0008494)
0.1	1.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	1.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.6	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	1.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1	0.5	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	1.6	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	0.3	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1	1.3	GO:0015266	protein channel activity(GO:0015266)
0.1	0.9	GO:0045545	syndecan binding(GO:0045545)
0.1	1.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	3.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.1	2.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.6	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.4	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.4	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	0.5	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.1	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.1	1.8	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	1.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.5	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.1	7.8	GO:0097110	scaffold protein binding(GO:0097110)
0.1	1.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	1.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.4	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	1.6	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.8	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.8	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.6	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	4.9	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	1.3	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.1	0.6	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.4	GO:1901618	organic hydroxy compound transmembrane transporter activity(GO:1901618)
0.1	1.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.4	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.6	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.4	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	2.9	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	0.1	GO:0097001	ceramide binding(GO:0097001)
0.1	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.7	GO:0008443	phosphofructokinase activity(GO:0008443)
0.1	0.8	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1	1.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.4	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	0.5	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	0.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.4	GO:0004774	succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	13.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.1	GO:0070052	collagen V binding(GO:0070052)
0.1	1.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.7	GO:0032190	acrosin binding(GO:0032190)
0.1	0.9	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	1.6	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	1.5	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	4.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	4.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1	4.8	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	0.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.5	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	1.4	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	4.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.1	0.3	GO:0097677	STAT family protein binding(GO:0097677)
0.1	0.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	3.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.2	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1	1.7	GO:0000146	microfilament motor activity(GO:0000146)
0.1	2.3	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.2	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1	1.0	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	2.1	GO:0070878	primary miRNA binding(GO:0070878)
0.1	1.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.8	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1	0.4	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1	0.3	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.1	0.3	GO:0043295	glutathione binding(GO:0043295)
0.1	0.8	GO:0016722	oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.1	0.5	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1	0.1	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1	4.8	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	0.4	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	1.7	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.1	GO:0022829	wide pore channel activity(GO:0022829)
0.1	0.9	GO:0004985	opioid receptor activity(GO:0004985)
0.1	25.2	GO:0003924	GTPase activity(GO:0003924)
0.1	0.1	GO:0015665	alcohol transmembrane transporter activity(GO:0015665)
0.1	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.1	0.4	GO:0015350	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.5	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.4	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1	3.7	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.4	GO:0050436	microfibril binding(GO:0050436)
0.1	1.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.2	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1	0.5	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	3.2	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.1	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.8	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.9	GO:0043426	MRF binding(GO:0043426)
0.1	0.2	GO:0035254	glutamate receptor binding(GO:0035254)
0.1	0.4	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.5	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.1	2.3	GO:0005123	death receptor binding(GO:0005123)
0.1	0.3	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1	0.8	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.1	GO:0016433	rRNA (adenine) methyltransferase activity(GO:0016433)
0.1	2.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.4	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	1.0	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.3	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	0.4	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1	2.7	GO:0019956	chemokine binding(GO:0019956)
0.1	0.4	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	1.9	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.1	1.5	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.1	3.0	GO:0005272	sodium channel activity(GO:0005272)
0.1	0.7	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.5	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	0.4	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1	3.8	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.3	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.1	0.1	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	9.5	GO:0044325	ion channel binding(GO:0044325)
0.1	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	2.3	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	0.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.3	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.1	3.7	GO:0019894	kinesin binding(GO:0019894)
0.1	2.6	GO:0030276	clathrin binding(GO:0030276)
0.1	0.3	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1	0.2	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	0.4	GO:0034597	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1	0.4	GO:0000182	rDNA binding(GO:0000182)
0.1	0.4	GO:0032217	riboflavin transporter activity(GO:0032217)
0.1	0.3	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.1	0.4	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	0.6	GO:0031402	sodium ion binding(GO:0031402)
0.1	0.3	GO:0052726	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1	0.8	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	0.3	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.3	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.3	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.3	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.5	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.3	GO:0070404	NADH binding(GO:0070404)
0.1	0.5	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.3	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	1.6	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	1.3	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.5	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.2	GO:0016417	S-acyltransferase activity(GO:0016417)
0.1	0.7	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.8	GO:0042301	phosphate ion binding(GO:0042301)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.1	GO:0045182	translation regulator activity(GO:0045182)
0.1	0.7	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	0.3	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.1	1.7	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.2	GO:0070402	NADPH binding(GO:0070402)
0.1	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.5	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1	0.6	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.2	GO:0004947	bradykinin receptor activity(GO:0004947)
0.1	1.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.1	0.2	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.1	0.9	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	2.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	4.0	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1	1.5	GO:0005518	collagen binding(GO:0005518)
0.1	0.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.5	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.2	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1	0.4	GO:1990239	steroid hormone binding(GO:1990239)
0.1	0.3	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1	0.6	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.4	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.1	0.3	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.1	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1	0.2	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	0.3	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.1	14.9	GO:0051015	actin filament binding(GO:0051015)
0.1	1.7	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1	0.4	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.8	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.1	0.4	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1	1.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.1	1.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.1	0.2	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.1	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	1.1	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.3	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	3.0	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.1	2.0	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.1	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.2	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	0.1	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.1	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.2	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.5	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1	0.5	GO:0008172	S-methyltransferase activity(GO:0008172)
0.1	0.2	GO:0005549	odorant binding(GO:0005549)
0.1	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	0.3	GO:0048185	activin binding(GO:0048185)
0.1	0.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	0.5	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.6	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	0.6	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.5	GO:0098505	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.1	0.1	GO:0004040	amidase activity(GO:0004040)
0.1	0.6	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	3.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0016015	morphogen activity(GO:0016015)
0.1	0.8	GO:0030515	snoRNA binding(GO:0030515)
0.1	0.1	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.1	15.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.6	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1	0.5	GO:0015385	monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	0.7	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.2	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.1	0.4	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.2	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.4	GO:0016416	O-palmitoyltransferase activity(GO:0016416)
0.1	6.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	0.1	GO:0022832	voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.1	0.1	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1	4.3	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.1	1.5	GO:0001972	retinoic acid binding(GO:0001972)
0.1	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	1.5	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.1	0.2	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	2.8	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1	0.2	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0016748	5-aminolevulinate synthase activity(GO:0003870) succinyltransferase activity(GO:0016748) N-succinyltransferase activity(GO:0016749)
0.1	1.7	GO:0000049	tRNA binding(GO:0000049)
0.1	0.9	GO:0070628	proteasome binding(GO:0070628)
0.1	0.5	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1	0.2	GO:0003678	DNA helicase activity(GO:0003678)
0.1	0.2	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.1	0.2	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1	0.2	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.1	0.8	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	1.0	GO:0005416	cation:amino acid symporter activity(GO:0005416)
0.1	1.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.2	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	0.2	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1	3.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.1	0.4	GO:0015250	water channel activity(GO:0015250)
0.1	0.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.4	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	0.4	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.5	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	0.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	0.1	GO:0022839	ion gated channel activity(GO:0022839)
0.1	0.2	GO:0043236	laminin binding(GO:0043236)
0.1	2.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.4	GO:0031996	thioesterase binding(GO:0031996)
0.1	0.2	GO:0035276	ethanol binding(GO:0035276)
0.1	0.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.8	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0016429	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0	0.9	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.7	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.0	GO:1901611	phosphatidylglycerol binding(GO:1901611)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.7	GO:0019208	phosphatase regulator activity(GO:0019208)
0.0	1.6	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.5	GO:0070513	death domain binding(GO:0070513)
0.0	1.2	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.6	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	1.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0004913	interleukin-4 receptor activity(GO:0004913)
0.0	2.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	1.3	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.2	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.0	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	1.7	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.6	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	1.0	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.5	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.0	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.0	0.0	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0	1.0	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.0	0.1	GO:0016499	orexin receptor activity(GO:0016499)
0.0	0.5	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	1.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.8	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.4	GO:0004527	exonuclease activity(GO:0004527)
0.0	7.2	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.2	GO:0099604	intracellular ligand-gated ion channel activity(GO:0005217) calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.3	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.9	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0017129	triglyceride binding(GO:0017129)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.1	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0	0.9	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.0	GO:0048763	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	5.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.2	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.4	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0042019	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.5	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.0	0.1	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.4	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	2.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	1.2	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.0	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.4	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.5	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.5	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0032089	NACHT domain binding(GO:0032089)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.1	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.1	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.0	0.2	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.1	GO:0004877	complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.0	0.1	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.0	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.0	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	1.4	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.4	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.1	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.6	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0015116	secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.0	0.0	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0001632	leukotriene B4 receptor activity(GO:0001632)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.0	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0	0.4	GO:0034212	peptide N-acetyltransferase activity(GO:0034212)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.0	GO:1990763	arrestin family protein binding(GO:1990763)
0.0	0.0	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.0	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	0.0	GO:0017130	poly(C) RNA binding(GO:0017130)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	2.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	3.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	5.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	3.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.6	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.7	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	1.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.2	GO:0003383	apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
0.1	0.2	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.0	0.2	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0	0.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.0	0.6	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0	0.3	GO:0000185	activation of MAPKKK activity(GO:0000185)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	14.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	3.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	3.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	12.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	4.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	3.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2	2.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	2.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	4.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	3.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	4.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	1.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	4.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	4.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	3.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	3.6	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	1.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	3.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	1.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	2.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	6.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	2.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	5.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	4.2	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.1	1.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	2.1	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	2.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	1.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	6.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	0.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	0.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	4.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	2.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	3.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.6	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	1.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	7.1	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.4	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	1.7	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	1.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.1	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.0	0.3	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.8	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	2.1	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	1.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	2.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.6	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	2.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.7	GO:0051796	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.9	3.8	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.9	7.9	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.8	2.4	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.6	1.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.5	1.5	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5	1.5	GO:0060166	olfactory pit development(GO:0060166)
0.4	1.5	GO:0003409	optic cup structural organization(GO:0003409)
0.4	2.3	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4	1.1	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3	0.6	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.3	2.8	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3	0.9	GO:2000360	positive regulation of female gonad development(GO:2000196) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.3	0.8	GO:1903028	positive regulation of opsonization(GO:1903028)
0.3	1.1	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.3	0.5	GO:0002159	desmosome assembly(GO:0002159)
0.2	0.2	GO:0060023	soft palate development(GO:0060023)
0.2	0.7	GO:1903519	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2	0.7	GO:0044209	AMP salvage(GO:0044209)
0.2	0.7	GO:1902227	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.2	0.6	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.2	0.6	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.2	1.8	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.2	2.2	GO:0009414	response to water deprivation(GO:0009414)
0.2	0.4	GO:1905247	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2	2.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.2	1.0	GO:0007296	vitellogenesis(GO:0007296)
0.2	0.8	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2	0.2	GO:0072054	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.2	2.6	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	1.0	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1	0.9	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.1	0.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.1	0.6	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	1.5	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1	0.9	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.1	0.1	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1	0.7	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	0.7	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1	0.1	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	0.6	GO:0097021	Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1	0.4	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.1	0.6	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.6	GO:0009440	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1	0.1	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.1	1.7	GO:0035878	nail development(GO:0035878)
0.1	0.8	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.3	GO:0006097	glyoxylate cycle(GO:0006097)
0.1	12.3	GO:0070268	cornification(GO:0070268)
0.1	1.6	GO:0046415	urate metabolic process(GO:0046415)
0.1	0.7	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.8	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1	5.3	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.1	0.4	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	0.3	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.1	1.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.4	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.1	0.3	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1	0.4	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	0.4	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	2.4	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.1	0.4	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.1	0.5	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.6	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.5	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.1	0.2	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.1	0.5	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1	0.3	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.1	0.4	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	0.4	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	0.4	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.3	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.1	1.6	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.5	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.1	4.9	GO:2000649	regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1	0.2	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.1	0.1	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.1	0.2	GO:1903572	coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1	0.2	GO:0097178	ruffle assembly(GO:0097178)
0.1	1.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	1.3	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	0.5	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	1.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.1	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
0.1	0.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.1	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.1	0.2	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.1	1.1	GO:0031424	keratinization(GO:0031424)
0.1	0.6	GO:0015868	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1	0.5	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.2	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.0	0.6	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.2	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.8	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.3	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.2	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.0	0.1	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0	0.0	GO:0010157	response to chlorate(GO:0010157)
0.0	0.3	GO:0036337	Fas signaling pathway(GO:0036337)
0.0	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0042369	vitamin D catabolic process(GO:0042369)
0.0	0.2	GO:1905073	occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.5	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	3.5	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.2	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.0	0.3	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
0.0	0.2	GO:0071321	cellular response to cGMP(GO:0071321)
0.0	0.1	GO:1904351	negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0	0.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0003406	retinal pigment epithelium development(GO:0003406) regulation of eye pigmentation(GO:0048073)
0.0	0.1	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0	0.2	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.2	GO:1902896	terminal web assembly(GO:1902896)
0.0	0.4	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0050894	determination of affect(GO:0050894)
0.0	0.2	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.4	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0046684	response to pyrethroid(GO:0046684) phytoalexin metabolic process(GO:0052314)
0.0	1.3	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.1	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0	0.5	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.1	GO:1904744	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
0.0	0.1	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0	0.2	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.0	0.1	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0	0.2	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.1	GO:0038163	endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0	0.1	GO:1903721	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0	0.4	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.4	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.3	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.6	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.3	GO:0097267	omega-hydroxylase P450 pathway(GO:0097267)
0.0	0.6	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.4	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	1.2	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
0.0	0.1	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0	0.2	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.2	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:0009386	translational attenuation(GO:0009386)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	1.0	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.2	GO:0014029	neural crest formation(GO:0014029)
0.0	0.4	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.9	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.2	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.2	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.1	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.2	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.4	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.4	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.2	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.3	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0	0.1	GO:0032571	response to vitamin K(GO:0032571)
0.0	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.0	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
0.0	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.7	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.0	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.0	0.2	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:1905024	regulation of potassium ion export(GO:1902302) regulation of potassium ion import(GO:1903286) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.0	0.7	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.2	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.1	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.1	GO:0032581	ER-dependent peroxisome organization(GO:0032581)
0.0	0.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.2	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	2.1	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.2	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	1.3	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.4	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.4	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:0044211	CTP salvage(GO:0044211)
0.0	0.0	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0	0.2	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0071105	response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0	0.1	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.0	0.1	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.2	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.1	GO:0051971	positive regulation of transmission of nerve impulse(GO:0051971)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.2	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.0	GO:0010041	response to iron(III) ion(GO:0010041) regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) cellular response to iron(III) ion(GO:0071283) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0	0.5	GO:0006363	transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0	0.2	GO:0008211	glucocorticoid metabolic process(GO:0008211)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.4	GO:0032773	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.7	2.0	GO:0060166	olfactory pit development(GO:0060166)
0.6	2.3	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.5	1.5	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.4	2.1	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.3	1.4	GO:0071461	cellular response to redox state(GO:0071461)
0.3	1.3	GO:1903288	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.3	1.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.3	0.8	GO:0045659	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2	2.7	GO:0002934	desmosome organization(GO:0002934)
0.2	0.9	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.2	1.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2	2.3	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.2	1.4	GO:0033590	response to cobalamin(GO:0033590)
0.2	0.9	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.2	0.6	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2	0.5	GO:0098904	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) regulation of AV node cell action potential(GO:0098904) regulation of bundle of His cell action potential(GO:0098905)
0.2	0.7	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2	0.9	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.2	1.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.2	1.7	GO:0009414	response to water deprivation(GO:0009414)
0.2	0.5	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1	0.4	GO:0050917	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1	0.4	GO:0006014	D-ribose metabolic process(GO:0006014)
0.1	1.4	GO:0051552	flavone metabolic process(GO:0051552)
0.1	0.4	GO:0023016	signal transduction by trans-phosphorylation(GO:0023016)
0.1	0.4	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1	0.8	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1	0.6	GO:1903273	regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.1	1.5	GO:0019388	galactose catabolic process(GO:0019388)
0.1	0.5	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	0.6	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	0.3	GO:0002384	hepatic immune response(GO:0002384)
0.1	0.7	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1	0.5	GO:1904693	midbrain morphogenesis(GO:1904693)
0.1	1.4	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	1.4	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.1	0.4	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.9	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.2	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.1	0.2	GO:0021569	rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.1	GO:0006258	UDP-glucose catabolic process(GO:0006258)
0.1	0.2	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1	1.8	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.1	1.4	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.3	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.1	0.2	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1	0.5	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.3	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.1	0.4	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.5	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	0.3	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.3	GO:0072423	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1	0.3	GO:0061143	alveolar primary septum development(GO:0061143)
0.1	0.2	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	1.1	GO:0035641	locomotory exploration behavior(GO:0035641)
0.1	0.4	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.2	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.1	1.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.1	GO:0033077	T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.1	1.3	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1	0.2	GO:1904404	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1	0.3	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.6	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0	0.2	GO:0030822	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0	0.9	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.4	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.2	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.0	0.1	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0	0.4	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	1.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	1.0	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.2	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.3	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.4	GO:0070836	caveola assembly(GO:0070836)
0.0	0.6	GO:0006853	carnitine shuttle(GO:0006853)
0.0	1.0	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:0009078	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.6	GO:0060347	heart trabecula formation(GO:0060347)
0.0	0.9	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.3	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.1	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.0	0.2	GO:0043385	mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0	0.1	GO:0050894	determination of affect(GO:0050894)
0.0	0.2	GO:0001999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	1.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.3	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	2.9	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.2	GO:0035634	response to stilbenoid(GO:0035634)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:0061113	signal transduction downstream of smoothened(GO:0007227) ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) pancreas morphogenesis(GO:0061113)
0.0	0.4	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.6	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.7	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.5	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	2.0	GO:0006024	aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.3	GO:0061458	reproductive system development(GO:0061458)
0.0	0.1	GO:0003073	regulation of systemic arterial blood pressure(GO:0003073)
0.0	0.3	GO:0090141	positive regulation of mitochondrial fission(GO:0090141)
0.0	0.3	GO:2000480	negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.1	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0	0.8	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0003335	corneocyte development(GO:0003335)
0.0	0.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.4	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.7	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.0	0.4	GO:0006970	response to osmotic stress(GO:0006970)
0.0	0.3	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.8	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.3	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839) venous blood vessel morphogenesis(GO:0048845)
0.0	0.7	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.4	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0	0.0	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0	0.2	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.3	GO:0051412	response to corticosterone(GO:0051412)
0.0	0.0	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.4	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.1	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0	0.1	GO:0060019	radial glial cell differentiation(GO:0060019)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	3.9	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.9	4.5	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.8	7.4	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.8	5.4	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.7	2.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.7	2.0	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.7	2.0	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
0.6	1.9	GO:1904479	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.6	3.2	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.6	7.6	GO:0045059	positive thymic T cell selection(GO:0045059)
0.6	1.7	GO:0006059	hexitol metabolic process(GO:0006059)
0.6	1.7	GO:1902995	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.5	2.6	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.5	1.5	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.5	1.4	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.5	1.4	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.3	0.7	GO:1902661	negative regulation of histone H3-K9 dimethylation(GO:1900110) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.3	1.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.3	2.0	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3	1.7	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3	2.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.3	1.3	GO:0070982	L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.3	4.0	GO:0015671	oxygen transport(GO:0015671)
0.3	0.9	GO:0044805	late nucleophagy(GO:0044805)
0.3	3.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3	1.4	GO:1902896	terminal web assembly(GO:1902896)
0.3	1.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.3	1.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.3	1.6	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3	0.8	GO:0016095	polyprenol catabolic process(GO:0016095)
0.3	6.9	GO:0006337	nucleosome disassembly(GO:0006337)
0.3	1.3	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.3	0.8	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.3	1.0	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.2	0.7	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.2	3.0	GO:0034392	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2	1.2	GO:0046203	spermidine catabolic process(GO:0046203)
0.2	7.2	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2	0.7	GO:0046521	sphingoid catabolic process(GO:0046521)
0.2	0.9	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.2	1.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.2	0.7	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.2	0.4	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2	0.6	GO:0018095	protein polyglutamylation(GO:0018095)
0.2	1.1	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.2	0.6	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.2	0.4	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.2	2.7	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2	0.8	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.2	1.4	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.2	0.4	GO:0031497	chromatin assembly(GO:0031497)
0.2	0.6	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.2	1.8	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.6	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2	0.8	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.2	0.6	GO:0021558	midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
0.2	1.3	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2	0.5	GO:0032242	regulation of nucleoside transport(GO:0032242)
0.2	0.5	GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.2	0.2	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.2	0.9	GO:0070383	DNA cytosine deamination(GO:0070383)
0.2	0.5	GO:0032203	telomere formation via telomerase(GO:0032203)
0.2	0.5	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.2	0.5	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.2	1.7	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.2	0.7	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2	1.0	GO:0051013	microtubule severing(GO:0051013)
0.2	0.7	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2	1.3	GO:0070475	rRNA base methylation(GO:0070475)
0.2	0.5	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2	0.5	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2	0.5	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
0.2	0.5	GO:0009258	10-formyltetrahydrofolate catabolic process(GO:0009258)
0.2	0.5	GO:0072092	ureteric bud invasion(GO:0072092)
0.2	0.6	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1	0.6	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1	0.4	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.1	1.3	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1	0.4	GO:2001162	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1	0.3	GO:0006711	estrogen catabolic process(GO:0006711)
0.1	0.6	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.4	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	0.4	GO:0071423	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1	0.4	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.1	0.5	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.1	0.4	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.5	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.1	0.5	GO:0048254	snoRNA localization(GO:0048254)
0.1	1.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.5	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	1.9	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1	0.1	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.1	0.4	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1	0.4	GO:1904482	response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1	1.1	GO:0035799	ureter maturation(GO:0035799)
0.1	1.6	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.5	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	0.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.1	0.6	GO:0001315	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1	0.3	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.5	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of glutamate metabolic process(GO:2000211)
0.1	0.8	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.7	GO:0035795	negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1	0.3	GO:0031627	telomeric loop formation(GO:0031627) negative regulation of t-circle formation(GO:1904430)
0.1	0.3	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.1	0.5	GO:0031337	cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1	2.7	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1	0.5	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.4	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1	0.3	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.9	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1	0.3	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	0.3	GO:0048022	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1	0.3	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1	0.7	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.1	4.7	GO:0051031	tRNA transport(GO:0051031)
0.1	0.1	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1	0.4	GO:1903644	regulation of chaperone-mediated protein folding(GO:1903644)
0.1	0.4	GO:0038155	interleukin-23-mediated signaling pathway(GO:0038155)
0.1	0.6	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.1	0.3	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.8	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.4	GO:1903721	regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1	0.4	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	0.5	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.1	0.6	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.1	0.7	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.1	0.3	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.1	0.5	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.3	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	0.7	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.3	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	1.1	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.1	0.8	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	0.3	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1	0.7	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.1	GO:0071352	cellular response to interleukin-2(GO:0071352)
0.1	0.3	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1	0.7	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.5	GO:0007018	microtubule-based movement(GO:0007018)
0.1	0.5	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.6	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.2	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	0.6	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.5	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	0.8	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	1.1	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.7	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.1	1.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0086098	angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.1	1.0	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	0.7	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.4	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.1	1.0	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.1	0.9	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.1	0.1	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1	0.4	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1	0.3	GO:0031648	protein destabilization(GO:0031648)
0.1	0.2	GO:1901355	response to rapamycin(GO:1901355)
0.1	0.3	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1	0.5	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.4	GO:0070091	response to selenium ion(GO:0010269) glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1	0.3	GO:0046035	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.2	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.1	0.7	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.1	0.9	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	4.7	GO:0070125	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1	0.4	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	0.1	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
0.1	0.3	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.1	0.9	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1	0.6	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.4	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.1	1.2	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1	0.1	GO:0042698	ovulation cycle(GO:0042698)
0.1	0.3	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.1	2.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	0.8	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.5	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.1	0.6	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.1	0.2	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	0.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.3	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	0.5	GO:0006116	NADH oxidation(GO:0006116)
0.1	0.3	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.9	GO:0021534	cell proliferation in hindbrain(GO:0021534)
0.1	0.3	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	0.7	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.4	GO:2000546	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1	0.5	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.1	0.3	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.1	0.4	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.1	0.7	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.1	1.4	GO:0051290	protein heterotetramerization(GO:0051290)
0.1	0.5	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.1	0.7	GO:0045008	depyrimidination(GO:0045008)
0.1	1.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	0.4	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.1	0.7	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.2	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.3	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.0	0.3	GO:0002034	regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0	0.4	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.1	GO:1901159	glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0	2.0	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.6	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.3	GO:0016180	snRNA processing(GO:0016180)
0.0	0.9	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.8	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.4	GO:1903027	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0	0.4	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.0	0.5	GO:0015868	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0	0.9	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.7	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.7	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.5	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0	0.5	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.8	GO:0006768	biotin metabolic process(GO:0006768)
0.0	1.3	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.2	GO:0046322	protein processing involved in protein targeting to mitochondrion(GO:0006627) negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.4	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.5	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.5	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	1.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.2	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	1.0	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.1	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0	1.5	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.3	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.4	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0	0.1	GO:0006550	isoleucine catabolic process(GO:0006550) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0	0.3	GO:0034447	positive regulation of sequestering of triglyceride(GO:0010890) very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.2	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.0	0.2	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	2.2	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.5	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.4	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0	0.2	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:0001714	endodermal cell fate specification(GO:0001714)
0.0	0.2	GO:1902739	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0	0.5	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.0	0.2	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.2	GO:0006196	AMP catabolic process(GO:0006196)
0.0	0.2	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0050757	thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
0.0	0.4	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.0	0.3	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.0	0.0	GO:0031291	Ran protein signal transduction(GO:0031291)
0.0	0.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
0.0	0.2	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.4	GO:0038202	TORC1 signaling(GO:0038202)
0.0	0.3	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.7	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.3	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.3	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.4	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) abortive mitotic cell cycle(GO:0033277)
0.0	0.1	GO:1904301	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.0	0.2	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.3	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.3	GO:0045927	positive regulation of growth(GO:0045927)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.4	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.4	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0045210	negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0	0.9	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.3	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.0	0.1	GO:0007140	male meiosis(GO:0007140)
0.0	0.2	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.3	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.1	GO:0042351	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0	0.5	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.1	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.0	GO:0031938	regulation of chromatin silencing at telomere(GO:0031938)
0.0	0.3	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.6	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.7	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.3	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	0.2	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0	2.0	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.3	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.2	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.4	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.9	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.1	GO:0042640	anagen(GO:0042640) negative regulation of defense response to bacterium(GO:1900425)
0.0	1.2	GO:0006400	tRNA modification(GO:0006400)
0.0	0.2	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.3	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:1900369	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	1.1	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:2001178	mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0	0.6	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.4	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.3	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.2	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.2	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.6	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.5	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.8	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.6	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.3	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	0.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.6	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0090042	tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0	0.2	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.5	GO:0098743	cell aggregation(GO:0098743)
0.0	0.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.3	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.2	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.0	GO:0019860	uracil metabolic process(GO:0019860)
0.0	0.1	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0	1.9	GO:0016575	histone deacetylation(GO:0016575)
0.0	1.1	GO:0060135	maternal process involved in female pregnancy(GO:0060135)
0.0	0.1	GO:0050960	detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0	0.4	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0034982	mitochondrial protein processing(GO:0034982)
0.0	0.2	GO:0015705	iodide transport(GO:0015705)
0.0	0.2	GO:0070200	establishment of protein localization to telomere(GO:0070200)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.2	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.3	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.2	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.4	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.6	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.3	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.2	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	0.3	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.2	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.3	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.9	GO:0055092	cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0	0.2	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.7	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.2	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.0	0.3	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.2	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0	0.5	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.0	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0042262	DNA protection(GO:0042262)
0.0	0.0	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0048749	compound eye development(GO:0048749)
0.0	0.2	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.2	GO:0002643	regulation of tolerance induction(GO:0002643)
0.0	0.5	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.1	GO:0032218	riboflavin transport(GO:0032218)
0.0	0.2	GO:0044818	mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
0.0	0.2	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.5	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.2	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.4	GO:0042438	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.2	GO:1901663	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.3	GO:0008033	tRNA processing(GO:0008033)
0.0	0.2	GO:0097186	amelogenesis(GO:0097186)
0.0	0.1	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0043486	histone exchange(GO:0043486)
0.0	0.1	GO:0018210	peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0	0.1	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0	0.1	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.3	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.2	GO:0006301	postreplication repair(GO:0006301)
0.0	0.2	GO:0030261	chromosome condensation(GO:0030261)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.3	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2	0.6	GO:1990523	bone regeneration(GO:1990523)
0.2	0.8	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2	1.0	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1	0.4	GO:0036512	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1	0.8	GO:0051012	microtubule sliding(GO:0051012)
0.1	2.8	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.3	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	0.3	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.7	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.1	0.2	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.3	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.5	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	0.2	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1	0.3	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1	0.2	GO:1904640	response to methionine(GO:1904640)
0.0	0.1	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.0	0.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.6	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0044861	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.2	GO:0048880	sensory system development(GO:0048880)
0.0	0.3	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.2	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.0	0.2	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.0	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.2	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.5	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.3	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.1	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.5	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.1	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.0	0.8	GO:0050819	negative regulation of coagulation(GO:0050819)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	NABA COLLAGENS	Genes encoding collagen proteins
0.0	1.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.6	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	2.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.1	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.4	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	1.5	PID FGF PATHWAY	FGF signaling pathway
0.0	0.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.3	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	17.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	9.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	18.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	5.2	NABA COLLAGENS	Genes encoding collagen proteins
0.1	7.0	PID IGF1 PATHWAY	IGF1 pathway
0.1	2.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	0.6	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	1.8	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	0.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	9.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	0.8	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	3.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	2.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.8	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	7.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	1.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.9	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	1.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.4	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.5	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.2	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.5	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.4	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.7	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
1.5	4.4	GO:0009107	lipoate biosynthetic process(GO:0009107)
1.2	1.2	GO:0009106	lipoate metabolic process(GO:0009106)
0.9	3.6	GO:0009386	translational attenuation(GO:0009386)
0.8	7.4	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.8	2.4	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.8	2.3	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.8	2.3	GO:0071314	cellular response to cocaine(GO:0071314)
0.7	2.9	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.7	2.0	GO:1990519	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.6	1.9	GO:0070512	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.6	1.8	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.6	1.8	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.6	2.9	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.6	2.9	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.6	1.7	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.5	2.7	GO:0048539	bone marrow development(GO:0048539)
0.5	3.1	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.5	1.5	GO:0021571	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5	1.5	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.5	4.0	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.5	1.5	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.5	2.4	GO:0048388	endosomal lumen acidification(GO:0048388)
0.5	1.4	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.4	2.5	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.4	0.8	GO:0043400	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.4	4.5	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.4	1.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.4	1.1	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.4	1.1	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
0.4	1.9	GO:1904073	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4	0.4	GO:0043103	hypoxanthine salvage(GO:0043103)
0.4	1.1	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
0.3	1.0	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3	1.4	GO:0045829	negative regulation of isotype switching(GO:0045829)
0.3	1.0	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.3	2.4	GO:0032202	telomere assembly(GO:0032202)
0.3	1.3	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.3	2.0	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3	2.0	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.3	1.0	GO:0045659	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3	2.5	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3	1.8	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.3	1.5	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.3	0.9	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3	0.9	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.3	1.1	GO:0046833	snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.3	1.7	GO:0021764	amygdala development(GO:0021764)
0.3	0.6	GO:1902728	positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.3	3.8	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3	2.2	GO:0016926	protein desumoylation(GO:0016926)
0.3	0.5	GO:0048511	rhythmic process(GO:0048511)
0.3	0.8	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.3	1.3	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3	1.0	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.3	0.8	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3	2.0	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.2	2.5	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2	1.0	GO:0003164	His-Purkinje system development(GO:0003164)
0.2	1.7	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.2	1.9	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.2	1.2	GO:0046601	positive regulation of centriole replication(GO:0046601)
0.2	0.7	GO:1990502	dense core granule maturation(GO:1990502)
0.2	0.7	GO:0072019	carbon dioxide transmembrane transport(GO:0035378) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.2	0.9	GO:0051664	nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.2	0.7	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.2	1.3	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2	0.9	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2	1.1	GO:0030070	insulin processing(GO:0030070)
0.2	1.7	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.2	0.6	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.2	0.6	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
0.2	0.2	GO:0045976	negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2	0.4	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2	0.6	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.2	2.3	GO:0000050	urea cycle(GO:0000050)
0.2	0.6	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2	0.8	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.2	0.4	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.2	0.8	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.2	1.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2	0.9	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2	3.8	GO:0000732	strand displacement(GO:0000732)
0.2	0.5	GO:0010845	positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2	0.5	GO:0043605	cellular amide catabolic process(GO:0043605)
0.2	0.2	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2	1.1	GO:0035709	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2	1.0	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.2	0.7	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.2	0.3	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.2	0.7	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2	0.8	GO:0080009	mRNA methylation(GO:0080009)
0.2	1.5	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.2	1.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.2	1.1	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2	2.6	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.2	2.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.2	0.5	GO:1903978	negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.2	0.8	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2	1.7	GO:0033227	dsRNA transport(GO:0033227)
0.2	2.0	GO:0072520	seminiferous tubule development(GO:0072520)
0.2	0.5	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.2	0.5	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1	0.3	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.1	0.7	GO:0035900	response to isolation stress(GO:0035900)
0.1	0.4	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1	0.4	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.1	0.9	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.3	GO:0036476	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1	0.7	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1	1.0	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	2.8	GO:0035855	megakaryocyte development(GO:0035855)
0.1	1.1	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	2.7	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.1	0.4	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.8	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.1	0.5	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1	0.1	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1	0.8	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.4	GO:0043449	olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.1	0.8	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	1.1	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.5	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	0.4	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.9	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.1	0.3	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1	0.3	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	0.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.1	0.2	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.1	0.5	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	1.3	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	0.8	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	2.1	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1	2.0	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	2.0	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	0.4	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	1.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.1	0.8	GO:0031053	primary miRNA processing(GO:0031053)
0.1	0.4	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1	5.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.1	0.6	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	1.0	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.3	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	6.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	3.8	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1	0.3	GO:0036090	cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
0.1	0.6	GO:0098707	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1	0.2	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.1	1.2	GO:0000729	DNA double-strand break processing(GO:0000729)
0.1	2.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.3	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.1	0.3	GO:0035377	transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1	2.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	0.4	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.3	GO:0072709	cellular response to sorbitol(GO:0072709)
0.1	0.3	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.1	2.7	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	0.3	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	1.7	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	1.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.1	1.2	GO:0010225	response to UV-C(GO:0010225)
0.1	0.1	GO:1990641	response to iron ion starvation(GO:1990641)
0.1	0.4	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	3.4	GO:0006270	DNA replication initiation(GO:0006270)
0.1	0.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1	1.0	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1	3.1	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1	0.2	GO:0014040	positive regulation of Schwann cell differentiation(GO:0014040)
0.1	1.5	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.5	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.3	GO:0071934	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1	0.2	GO:0048075	positive regulation of eye pigmentation(GO:0048075)
0.1	1.2	GO:0045475	locomotor rhythm(GO:0045475)
0.1	0.6	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.1	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1	0.3	GO:1903232	melanosome assembly(GO:1903232)
0.1	1.0	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.6	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0006711	estrogen catabolic process(GO:0006711)
0.1	0.2	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	0.9	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.1	0.3	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.1	0.5	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.1	0.2	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.4	GO:0003322	pancreatic A cell development(GO:0003322)
0.1	0.1	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	0.1	GO:0061511	centriole elongation(GO:0061511)
0.1	0.9	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.4	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.1	0.9	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.2	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.1	0.1	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.4	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	0.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.3	GO:0002879	positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1	0.2	GO:1903121	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1	0.3	GO:0043335	protein unfolding(GO:0043335)
0.1	0.6	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.7	GO:0018065	protein-cofactor linkage(GO:0018065)
0.1	0.3	GO:0060356	leucine import(GO:0060356)
0.1	0.8	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.1	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091)
0.1	1.2	GO:0019722	calcium-mediated signaling(GO:0019722)
0.1	5.0	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1	0.2	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	1.4	GO:0006379	mRNA cleavage(GO:0006379)
0.1	0.9	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.3	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.1	0.5	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1	0.5	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.1	2.1	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.3	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.4	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1	0.6	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.2	GO:0009726	detection of endogenous stimulus(GO:0009726)
0.1	0.5	GO:0006983	ER overload response(GO:0006983)
0.1	0.6	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	0.4	GO:1902570	protein localization to nucleolus(GO:1902570)
0.1	0.2	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.4	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.6	GO:0015889	cobalamin transport(GO:0015889)
0.1	1.3	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.1	0.8	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	0.4	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.1	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.1	1.1	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	0.6	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.2	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1	1.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	0.9	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.6	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.6	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.1	0.5	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.3	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1	0.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1	0.2	GO:1902941	positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1	0.2	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1	0.4	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.4	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	1.1	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	1.0	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.2	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.3	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	0.5	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1	0.2	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1	0.4	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1	0.1	GO:1903939	regulation of TORC2 signaling(GO:1903939)
0.1	0.6	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.2	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.0	0.2	GO:0071105	response to interleukin-11(GO:0071105)
0.0	0.3	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0	0.3	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	2.2	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.5	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.2	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.0	GO:0030388	sucrose biosynthetic process(GO:0005986) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	1.3	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.2	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.6	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.3	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0	0.5	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	1.5	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	1.2	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.3	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.9	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.3	GO:0052203	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.3	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	1.1	GO:0006309	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.3	GO:1902473	regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.0	0.6	GO:0021794	thalamus development(GO:0021794)
0.0	0.3	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.1	GO:1990637	response to prolactin(GO:1990637)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.4	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.4	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.2	GO:0030242	pexophagy(GO:0030242)
0.0	0.2	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.1	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.0	0.2	GO:1904781	cell-cell junction maintenance(GO:0045217) positive regulation of protein localization to centrosome(GO:1904781)
0.0	0.6	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.3	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.3	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.0	0.3	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0	0.2	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	1.0	GO:0018023	peptidyl-lysine trimethylation(GO:0018023)
0.0	1.6	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	1.6	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.7	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.2	GO:0099540	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.0	0.1	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.3	GO:0002237	response to molecule of bacterial origin(GO:0002237)
0.0	0.3	GO:1900376	regulation of melanin biosynthetic process(GO:0048021) positive regulation of melanin biosynthetic process(GO:0048023) regulation of secondary metabolite biosynthetic process(GO:1900376) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.5	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0006788	heme oxidation(GO:0006788)
0.0	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	2.5	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.3	GO:0070933	histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0	0.4	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	2.1	GO:0021762	substantia nigra development(GO:0021762)
0.0	0.0	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	2.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.3	GO:0032264	IMP salvage(GO:0032264)
0.0	0.3	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.4	GO:0009642	response to light intensity(GO:0009642)
0.0	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.8	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.9	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	1.2	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.6	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101) citrulline biosynthetic process(GO:0019240) histone citrullination(GO:0036414)
0.0	0.6	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.1	GO:0098758	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0	0.4	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	3.3	GO:0045333	cellular respiration(GO:0045333)
0.0	0.2	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.3	GO:0060969	negative regulation of gene silencing(GO:0060969)
0.0	0.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.4	GO:0044030	regulation of DNA methylation(GO:0044030)
0.0	0.4	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.4	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	1.0	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.1	GO:0061744	psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0	0.1	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.0	0.4	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	1.1	GO:0006342	chromatin silencing(GO:0006342)
0.0	0.1	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	1.9	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.2	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.2	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.9	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0	0.5	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.1	GO:0001777	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.3	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.0	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.2	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.0	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:1902564	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of neutrophil activation(GO:1902564)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.6	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	1.1	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.5	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.3	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.3	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.1	GO:0043153	photoperiodism(GO:0009648) entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.0	2.1	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0046967	cytosol to ER transport(GO:0046967)
0.0	1.2	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.4	GO:0010737	protein kinase A signaling(GO:0010737) regulation of protein kinase A signaling(GO:0010738)
0.0	0.4	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.2	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	1.3	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.2	GO:0034378	chylomicron assembly(GO:0034378)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.3	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0048867	stem cell fate determination(GO:0048867)
0.0	0.1	GO:1904152	regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0	0.4	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.1	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.2	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.0	0.7	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.5	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0	0.1	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	0.4	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.5	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.4	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.7	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.2	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.0	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.0	1.4	GO:0042472	inner ear morphogenesis(GO:0042472)
0.0	0.1	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.4	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.3	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0038155	interleukin-23-mediated signaling pathway(GO:0038155)
0.0	0.1	GO:1904640	response to methionine(GO:1904640)
0.0	0.5	GO:0009214	cAMP catabolic process(GO:0006198) cyclic nucleotide catabolic process(GO:0009214)
0.0	0.2	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:1903288	positive regulation of potassium ion import(GO:1903288)
0.0	0.6	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.1	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0	0.1	GO:1902669	positive regulation of axon guidance(GO:1902669)
0.0	0.1	GO:0003018	vascular process in circulatory system(GO:0003018) regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.0	0.6	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.1	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	2.0	GO:0050796	regulation of insulin secretion(GO:0050796)
0.0	0.5	GO:0015695	organic cation transport(GO:0015695)
0.0	0.9	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	1.4	GO:0006096	glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0	0.2	GO:0001510	RNA methylation(GO:0001510)
0.0	0.1	GO:0031113	regulation of microtubule polymerization(GO:0031113)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:2001223	negative regulation of neuron migration(GO:2001223)
0.0	0.1	GO:0075713	establishment of integrated proviral latency(GO:0075713)
0.0	0.0	GO:1902230	regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.2	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0	0.4	GO:0097503	sialylation(GO:0097503)
0.0	0.0	GO:0039656	modulation by virus of host transcription(GO:0019056) modulation by virus of host gene expression(GO:0039656) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0	0.0	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0097021	lymphocyte migration into lymphoid organs(GO:0097021)
0.0	0.3	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.0	0.0	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.1	GO:0002836	positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.0	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.0	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.2	GO:0030261	chromosome condensation(GO:0030261)
0.0	0.1	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
0.0	0.2	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.0	GO:1903936	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0	0.1	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.2	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0070170	regulation of tooth mineralization(GO:0070170)
0.0	0.2	GO:0009408	response to heat(GO:0009408)
0.0	0.9	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.0	GO:0002765	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.3	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.8	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.3	GO:0009948	anterior/posterior axis specification(GO:0009948)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.2	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	11.7	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
1.6	4.8	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.5	4.6	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
1.4	4.1	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.4	4.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
1.4	6.8	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
1.3	7.5	GO:0061649	ubiquitinated histone binding(GO:0061649)
1.2	3.6	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.1	3.4	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
1.0	7.2	GO:0030621	U4 snRNA binding(GO:0030621)
1.0	3.0	GO:0000992	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
1.0	3.9	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.9	4.7	GO:0016882	cyclo-ligase activity(GO:0016882)
0.9	2.7	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.9	3.5	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.9	2.6	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.8	4.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.8	3.3	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.8	2.4	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.7	2.2	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.7	2.1	GO:0097677	STAT family protein binding(GO:0097677)
0.7	4.7	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.7	1.3	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.6	2.6	GO:0001054	RNA polymerase I activity(GO:0001054)
0.6	3.2	GO:0070404	NADH binding(GO:0070404)
0.6	1.9	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.6	3.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.6	1.8	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.6	2.4	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.6	7.6	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.6	2.3	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.6	1.7	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.6	2.9	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.6	2.9	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.6	2.2	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.5	1.6	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.5	2.2	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.5	3.3	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.5	0.5	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.5	4.0	GO:0033613	activating transcription factor binding(GO:0033613)
0.5	5.0	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.5	10.5	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.5	2.4	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.5	0.5	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.5	3.9	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.5	3.4	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5	1.4	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.5	4.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.5	1.4	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.5	1.8	GO:0036033	mediator complex binding(GO:0036033)
0.5	0.9	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.4	6.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.4	1.3	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.4	2.1	GO:1990460	leptin receptor binding(GO:1990460)
0.4	3.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.4	1.6	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.4	1.2	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4	4.4	GO:0033592	RNA strand annealing activity(GO:0033592)
0.4	1.9	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.4	1.1	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.4	1.5	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.4	1.5	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.4	21.1	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.4	1.8	GO:0030348	syntaxin-3 binding(GO:0030348)
0.4	1.8	GO:0052846	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.3	10.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.3	1.7	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.3	1.4	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3	1.4	GO:0097001	ceramide binding(GO:0097001)
0.3	1.4	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.3	5.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.3	1.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.3	1.7	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.3	1.3	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.3	1.6	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.3	1.9	GO:0005499	vitamin D binding(GO:0005499)
0.3	1.9	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.3	3.7	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.3	1.2	GO:0043398	HLH domain binding(GO:0043398)
0.3	9.0	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.3	6.9	GO:0001056	RNA polymerase III activity(GO:0001056)
0.3	0.9	GO:0004040	amidase activity(GO:0004040)
0.3	3.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.3	5.0	GO:0003688	DNA replication origin binding(GO:0003688)
0.3	0.9	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.3	1.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3	1.7	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.3	3.5	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.3	0.9	GO:0015235	cobalamin transporter activity(GO:0015235)
0.3	6.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.3	1.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3	0.8	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.3	1.1	GO:0008410	CoA-transferase activity(GO:0008410)
0.3	1.4	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.3	1.6	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3	2.7	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.3	0.3	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.3	4.0	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.3	8.7	GO:0001671	ATPase activator activity(GO:0001671)
0.3	14.2	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.3	2.9	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.3	2.1	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.3	3.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3	1.0	GO:0032810	sterol response element binding(GO:0032810)
0.3	1.8	GO:0042979	ornithine decarboxylase activator activity(GO:0042978) ornithine decarboxylase regulator activity(GO:0042979)
0.2	1.2	GO:0070097	delta-catenin binding(GO:0070097)
0.2	0.7	GO:0005047	signal recognition particle binding(GO:0005047)
0.2	6.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.2	9.0	GO:0051059	NF-kappaB binding(GO:0051059)
0.2	1.4	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.2	1.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.2	1.6	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.2	3.9	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2	3.9	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2	5.2	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.2	13.9	GO:0034212	peptide N-acetyltransferase activity(GO:0034212)
0.2	6.9	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.2	1.1	GO:0070728	leucine binding(GO:0070728)
0.2	0.7	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.2	7.0	GO:0000049	tRNA binding(GO:0000049)
0.2	1.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	1.3	GO:0042296	ISG15 transferase activity(GO:0042296)
0.2	1.6	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.2	0.8	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.2	2.4	GO:0017070	U6 snRNA binding(GO:0017070)
0.2	2.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.2	2.8	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.2	2.3	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.2	1.5	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.2	2.8	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.2	0.9	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.2	5.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.2	2.6	GO:0016018	cyclosporin A binding(GO:0016018)
0.2	6.3	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.2	8.0	GO:0035064	methylated histone binding(GO:0035064)
0.2	2.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.2	11.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.2	3.8	GO:0004659	prenyltransferase activity(GO:0004659)
0.2	2.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.2	5.6	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2	0.7	GO:0008940	nitrate reductase activity(GO:0008940)
0.2	7.1	GO:0004532	exoribonuclease activity(GO:0004532)
0.2	1.7	GO:0031491	nucleosome binding(GO:0031491)
0.2	1.8	GO:0048156	tau protein binding(GO:0048156)
0.2	11.4	GO:0008186	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2	1.2	GO:0050733	RS domain binding(GO:0050733)
0.2	2.8	GO:0070513	death domain binding(GO:0070513)
0.2	1.0	GO:0030911	TPR domain binding(GO:0030911)
0.2	1.1	GO:0008142	oxysterol binding(GO:0008142)
0.2	0.6	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2	0.9	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2	0.6	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.2	2.1	GO:0070628	proteasome binding(GO:0070628)
0.2	33.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.2	1.5	GO:0015232	heme transporter activity(GO:0015232)
0.2	0.6	GO:0034603	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2	0.8	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.2	0.6	GO:0032408	purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701) MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2	1.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.2	4.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.9	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.1	11.2	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	1.6	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.6	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.1	0.9	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.1	2.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	1.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	2.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	3.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	1.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	3.6	GO:0043022	ribosome binding(GO:0043022)
0.1	2.4	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1	2.4	GO:0005522	profilin binding(GO:0005522)
0.1	6.6	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	3.9	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	2.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	9.9	GO:0042393	histone binding(GO:0042393)
0.1	0.4	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1	0.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	2.8	GO:0043274	phospholipase binding(GO:0043274)
0.1	3.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	0.9	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	10.1	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	0.5	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	1.3	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.4	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	2.9	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.1	0.7	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	2.4	GO:0005521	lamin binding(GO:0005521)
0.1	2.7	GO:0002039	p53 binding(GO:0002039)
0.1	1.6	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.1	1.3	GO:0032451	demethylase activity(GO:0032451)
0.1	0.6	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.5	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	1.7	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.8	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.1	2.6	GO:0005123	death receptor binding(GO:0005123)
0.1	0.7	GO:0017002	activin-activated receptor activity(GO:0017002)
0.1	3.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.8	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	1.0	GO:0016421	CoA carboxylase activity(GO:0016421)
0.1	0.5	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	1.5	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.6	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	1.9	GO:0050811	GABA receptor binding(GO:0050811)
0.1	5.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	1.0	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.7	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	2.3	GO:0019213	deacetylase activity(GO:0019213)
0.1	4.7	GO:0016836	hydro-lyase activity(GO:0016836)
0.1	0.8	GO:0000150	recombinase activity(GO:0000150)
0.1	0.8	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	6.6	GO:0003777	microtubule motor activity(GO:0003777)
0.1	1.8	GO:0031489	myosin V binding(GO:0031489)
0.1	1.7	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	0.4	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	14.9	GO:0061659	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1	1.3	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	0.6	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1	2.1	GO:0015248	sterol transporter activity(GO:0015248)
0.1	0.8	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.4	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.8	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	0.6	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.6	GO:0015288	porin activity(GO:0015288)
0.1	0.3	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	1.5	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	6.2	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.1	0.4	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.2	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.1	2.5	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	3.4	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.1	0.7	GO:0030515	snoRNA binding(GO:0030515)
0.1	1.2	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1	0.2	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	2.2	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	0.2	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.4	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	1.1	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	1.3	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.2	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.7	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	3.8	GO:0005516	calmodulin binding(GO:0005516)
0.0	1.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.0	2.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	4.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	1.9	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.6	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	1.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	81.7	GO:0003677	DNA binding(GO:0003677)
0.0	0.5	GO:0042608	T cell receptor binding(GO:0042608)
0.0	4.6	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.6	GO:0004518	nuclease activity(GO:0004518)
0.0	0.8	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	1.6	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.3	GO:0004386	helicase activity(GO:0004386)
0.0	1.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.9	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.8	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.3	GO:0016874	ligase activity(GO:0016874)
0.0	0.1	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0	0.4	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.8	GO:0051540	iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0	0.5	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.0	1.0	GO:0043531	ADP binding(GO:0043531)
0.0	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.6	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.4	GO:0005537	mannose binding(GO:0005537)
0.0	0.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	1.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.5	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	4.3	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	0.1	GO:0016972	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.0	0.4	GO:0004521	endoribonuclease activity(GO:0004521)
0.0	0.2	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.1	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	1.1	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.5	GO:0042605	peptide antigen binding(GO:0042605)
0.0	1.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.4	GO:0030145	manganese ion binding(GO:0030145)
0.0	1.0	GO:0016651	oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0	0.7	GO:0051087	chaperone binding(GO:0051087)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.4	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.4	GO:0043621	protein self-association(GO:0043621)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	0.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.8	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	1.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.2	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.8	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	2.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	10.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	6.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	4.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	10.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	0.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	5.6	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	2.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	7.1	GO:0010652	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
2.3	6.9	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
1.4	5.5	GO:0071461	cellular response to redox state(GO:0071461)
1.1	3.2	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.0	5.0	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
1.0	7.6	GO:0031642	negative regulation of myelination(GO:0031642)
0.8	3.4	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.7	3.3	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.6	2.4	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.5	1.5	GO:1902958	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.4	1.8	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.3	1.5	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3	8.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.3	1.7	GO:0036337	Fas signaling pathway(GO:0036337)
0.3	5.0	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.2	0.7	GO:1902445	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2	0.7	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.2	2.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	2.9	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2	12.8	GO:0032732	positive regulation of interleukin-1 production(GO:0032732)
0.2	0.6	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	1.7	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.2	0.8	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.2	2.7	GO:0046415	urate metabolic process(GO:0046415)
0.2	5.7	GO:0007398	ectoderm development(GO:0007398)
0.2	0.9	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.2	0.7	GO:1901377	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.2	0.2	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.2	3.7	GO:0036010	protein localization to endosome(GO:0036010)
0.2	2.0	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.2	4.2	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.2	6.0	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.1	0.6	GO:0019249	lactate biosynthetic process(GO:0019249)
0.1	2.5	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.7	GO:0030047	actin modification(GO:0030047)
0.1	3.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1	3.8	GO:0010226	response to lithium ion(GO:0010226)
0.1	0.4	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.1	1.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.4	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	1.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.1	6.2	GO:0018149	peptide cross-linking(GO:0018149)
0.1	2.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.4	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.1	0.4	GO:0006203	dGTP catabolic process(GO:0006203)
0.1	0.4	GO:0090131	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.1	0.3	GO:0044375	regulation of peroxisome size(GO:0044375)
0.1	0.5	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1	0.4	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	0.4	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479) formation of radial glial scaffolds(GO:0021943)
0.1	0.5	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.2	GO:0007497	posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.1	1.0	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.3	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1	1.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	1.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.7	GO:0016540	protein autoprocessing(GO:0016540)
0.0	1.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.8	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.3	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.9	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0	0.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055) protein localization to nucleolus(GO:1902570)
0.0	0.6	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.9	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.2	GO:0042746	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0	0.4	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.3	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.0	0.4	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	1.4	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0	3.9	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.5	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.2	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0	0.2	GO:0030091	protein repair(GO:0030091)
0.0	0.7	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.9	GO:0046949	fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0	0.3	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.5	GO:0019054	modulation by virus of host process(GO:0019054)
0.0	0.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.5	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.2	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	0.2	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.8	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.2	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955) dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.7	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.2	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0032218	riboflavin transport(GO:0032218)
0.0	0.4	GO:0007271	synaptic transmission, cholinergic(GO:0007271)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	26.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	29.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.2	11.4	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	2.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.3	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.4	9.8	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.6	6.4	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.8	3.0	GO:0097325	melanocyte proliferation(GO:0097325)
0.7	2.9	GO:0007525	somatic muscle development(GO:0007525)
0.7	7.4	GO:0009414	response to water deprivation(GO:0009414)
0.5	3.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.5	2.4	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.4	1.4	GO:0035995	detection of muscle stretch(GO:0035995)
0.3	1.8	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.2	1.7	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.2	0.5	GO:0021569	rhombomere 3 development(GO:0021569)
0.2	0.7	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2	2.1	GO:0038203	TORC2 signaling(GO:0038203)
0.2	0.7	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.2	1.1	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2	0.3	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.2	1.4	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.4	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1	0.4	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1	1.7	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	1.1	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	1.6	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	1.0	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	1.2	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.8	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.4	GO:0033123	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1	1.0	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.3	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.1	0.3	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1	0.7	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	1.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	0.3	GO:1904753	negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.1	0.4	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1	1.2	GO:0000338	protein deneddylation(GO:0000338)
0.1	0.4	GO:0072717	cellular response to actinomycin D(GO:0072717)
0.1	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.5	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1	0.2	GO:0021589	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1	0.7	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.1	4.9	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.1	1.1	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.1	1.3	GO:0032060	bleb assembly(GO:0032060)
0.1	0.6	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.6	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.1	0.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0061739	protein lipidation involved in autophagosome assembly(GO:0061739)
0.1	0.7	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.7	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	1.2	GO:0006853	carnitine shuttle(GO:0006853)
0.1	3.0	GO:0097435	fibril organization(GO:0097435)
0.1	0.6	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	3.5	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	0.3	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.1	0.4	GO:0032119	sequestering of zinc ion(GO:0032119)
0.1	0.4	GO:0003344	pericardium morphogenesis(GO:0003344)
0.1	0.3	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0	1.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	3.7	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.2	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	1.2	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	1.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.8	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:1901899	dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	1.4	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.6	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	2.7	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.4	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	1.1	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.1	GO:0072276	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0	0.7	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.0	0.1	GO:0009386	translational attenuation(GO:0009386)
0.0	5.6	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	1.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0060513	prostatic bud formation(GO:0060513)
0.0	0.1	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0	0.5	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.7	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:1903288	protein transport into plasma membrane raft(GO:0044861) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.7	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0035803	egg coat formation(GO:0035803)
0.0	0.3	GO:0035721	intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.1	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	1.1	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.0	1.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	1.5	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.4	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.2	GO:0007144	female meiosis I(GO:0007144)
0.0	1.5	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.2	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.4	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0	0.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.7	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.4	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.5	GO:0007398	ectoderm development(GO:0007398)
0.0	0.3	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.4	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.0	0.4	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	1.7	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.2	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.2	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.5	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0097352	autophagosome maturation(GO:0097352)
0.0	0.3	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.6	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	2.9	GO:0007517	muscle organ development(GO:0007517)
0.0	0.9	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.5	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.2	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:1902908	regulation of melanosome transport(GO:1902908) regulation of melanosome organization(GO:1903056)
0.0	0.1	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	1.2	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	1.1	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.8	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.4	GO:1990584	cardiac Troponin complex(GO:1990584)
0.2	0.6	GO:0097679	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.2	1.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	2.2	GO:0097512	cardiac myofibril(GO:0097512)
0.2	1.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.4	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	1.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	1.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	2.0	GO:0000145	exocyst(GO:0000145)
0.1	2.9	GO:0000421	autophagosome membrane(GO:0000421)
0.1	2.3	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.6	GO:0008091	spectrin(GO:0008091)
0.0	0.7	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.3	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.2	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.0	1.5	GO:0097546	ciliary base(GO:0097546)
0.0	0.9	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.6	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	4.9	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.0	0.7	GO:0071437	invadopodium(GO:0071437)
0.0	0.3	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	1.7	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0000124	SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0	1.0	GO:0044291	cell-cell contact zone(GO:0044291)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	2.6	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	3.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	2.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	2.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	2.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	1.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.0	PID ARF6 PATHWAY	Arf6 signaling events
0.0	5.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.6	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	2.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.7	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	0.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	1.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.0	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.7	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.8	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.0	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.5	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	2.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.6	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	2.9	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0005588	collagen type V trimer(GO:0005588)
0.2	3.3	GO:0030478	actin cap(GO:0030478)
0.2	1.7	GO:0016012	sarcoglycan complex(GO:0016012)
0.2	0.6	GO:0036028	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.2	1.0	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.2	2.2	GO:0097470	ribbon synapse(GO:0097470)
0.2	2.8	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.2	0.6	GO:0097060	synaptic membrane(GO:0097060)
0.1	0.6	GO:0031302	intrinsic component of endosome membrane(GO:0031302)
0.1	0.4	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	1.7	GO:0032433	filopodium tip(GO:0032433)
0.1	1.2	GO:0005916	fascia adherens(GO:0005916)
0.1	0.2	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1	1.9	GO:0031143	pseudopodium(GO:0031143)
0.1	0.2	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.9	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.4	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	0.3	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.1	0.2	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.5	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	1.1	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.1	0.2	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1	0.6	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	1.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	1.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.5	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0070557	PCNA-p21 complex(GO:0070557)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0071020	post-spliceosomal complex(GO:0071020)
0.0	0.2	GO:0097224	sperm connecting piece(GO:0097224)
0.0	0.4	GO:0005638	lamin filament(GO:0005638)
0.0	3.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.3	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.1	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.0	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.0	0.1	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.0	0.1	GO:0000811	GINS complex(GO:0000811)
0.0	0.2	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.1	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.7	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.5	GO:0005687	U4 snRNP(GO:0005687)
0.0	0.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.1	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.2	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0031673	H zone(GO:0031673)
0.0	0.1	GO:0045160	myosin I complex(GO:0045160)
0.0	0.2	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.6	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	2.2	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.1	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0	0.7	GO:0000421	autophagosome membrane(GO:0000421)
0.0	1.3	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.0	GO:0035838	growing cell tip(GO:0035838)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.6	GO:0032420	stereocilium(GO:0032420)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.9	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	3.6	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.0	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	1.1	GO:0005901	caveola(GO:0005901)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:1990423	RZZ complex(GO:1990423)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.3	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.9	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.5	GO:0005605	basal lamina(GO:0005605)
0.0	0.5	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.1	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.2	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.1	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	1.4	GO:0005884	actin filament(GO:0005884)
0.0	1.2	GO:0044216	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:1990584	cardiac Troponin complex(GO:1990584)
0.0	0.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	5.7	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.0	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:2000538	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2	0.5	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1	0.7	GO:1902896	terminal web assembly(GO:1902896)
0.1	0.3	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1	2.7	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	0.4	GO:0061143	alveolar primary septum development(GO:0061143)
0.1	1.2	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.1	1.7	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	0.2	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.4	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134)
0.1	0.3	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.2	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.5	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.3	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	1.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.5	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.2	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.1	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	5.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	3.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	3.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.7	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	2.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	0.9	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	1.0	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	4.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	5.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.0	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.8	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.2	GO:0008184	purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.2	0.6	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.1	1.0	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1	3.9	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	2.6	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.9	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.2	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.0	0.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.6	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	2.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	2.9	GO:0019003	GDP binding(GO:0019003)
0.0	0.3	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.4	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.2	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	2.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	2.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	3.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.6	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.0	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.4	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.9	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	2.5	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.2	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	1.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	2.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	1.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	0.9	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	0.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	1.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	2.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	3.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.7	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.3	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	1.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.2	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	3.0	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.8	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.2	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	1.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.3	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.8	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
1.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
1.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
1.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.5	REACTOME OPSINS	Genes involved in Opsins
0.0	3.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	6.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	5.6	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	1.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	1.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.3	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	1.2	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.4	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.6	GO:0042825	TAP complex(GO:0042825)
0.1	0.7	GO:0032010	phagolysosome(GO:0032010)
0.1	3.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.3	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.3	GO:1990769	proximal neuron projection(GO:1990769)
0.1	0.2	GO:0005873	plus-end kinesin complex(GO:0005873)
0.0	1.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.4	GO:0000125	PCAF complex(GO:0000125)
0.0	0.7	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	0.2	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.7	GO:0045095	keratin filament(GO:0045095)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0097179	protease inhibitor complex(GO:0097179)
0.0	1.1	GO:0005882	intermediate filament(GO:0005882)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	3.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	6.9	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
2.2	6.7	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
1.6	7.9	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
1.6	4.7	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
1.4	4.2	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
1.2	8.5	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.2	6.0	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
1.2	3.6	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
1.2	3.5	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
1.1	3.4	GO:0016730	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
1.1	6.3	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
1.0	3.1	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
1.0	5.2	GO:0016882	cyclo-ligase activity(GO:0016882)
1.0	3.0	GO:0036317	tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
1.0	4.9	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
1.0	3.8	GO:0016880	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
1.0	2.9	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.9	6.6	GO:0030621	U4 snRNA binding(GO:0030621)
0.9	4.6	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.9	5.5	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.9	2.7	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.9	2.7	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.9	1.8	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.8	2.5	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.8	2.5	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.8	0.8	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.8	1.6	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.8	4.9	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.8	3.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.8	14.1	GO:0001054	RNA polymerase I activity(GO:0001054)
0.8	2.3	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.8	3.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.7	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.7	2.2	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.7	2.9	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.7	2.2	GO:0031177	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.7	11.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.7	2.1	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.7	2.1	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.7	19.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.7	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.7	2.0	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.7	2.0	GO:0001181	transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.7	0.7	GO:0016208	AMP binding(GO:0016208)
0.6	1.9	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.6	1.9	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.6	16.7	GO:0030515	snoRNA binding(GO:0030515)
0.6	3.1	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.6	4.3	GO:0030620	U2 snRNA binding(GO:0030620)
0.6	8.4	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.6	1.8	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.6	8.9	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.6	2.3	GO:0032217	riboflavin transporter activity(GO:0032217)
0.6	2.9	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.6	2.3	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.6	1.7	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.6	2.2	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6	3.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.6	4.4	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5	3.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.5	0.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.5	1.6	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.5	7.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.5	2.1	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.5	2.6	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5	2.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.5	5.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.5	1.5	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.5	17.8	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.5	4.6	GO:0035174	histone serine kinase activity(GO:0035174)
0.5	5.0	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.5	2.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.5	1.0	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.5	0.5	GO:0004559	alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.5	2.9	GO:0051870	methotrexate binding(GO:0051870)
0.5	1.4	GO:0017130	poly(C) RNA binding(GO:0017130)
0.5	3.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.5	1.8	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.5	2.3	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.4	0.9	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
0.4	0.4	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.4	2.7	GO:0000405	bubble DNA binding(GO:0000405)
0.4	2.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.4	3.0	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.4	12.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.4	4.7	GO:0015266	protein channel activity(GO:0015266)
0.4	3.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.4	1.7	GO:0032810	sterol response element binding(GO:0032810)
0.4	4.9	GO:0035173	histone kinase activity(GO:0035173)
0.4	3.3	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.4	1.2	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.4	2.8	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.4	2.4	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.4	1.2	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.4	2.3	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.4	1.2	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.4	1.5	GO:0016504	peptidase activator activity(GO:0016504) peptidase activator activity involved in apoptotic process(GO:0016505)
0.4	3.1	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.4	1.1	GO:0015235	cobalamin transporter activity(GO:0015235)
0.4	1.1	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.4	1.1	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.4	1.5	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.4	2.9	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.4	7.1	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3	4.5	GO:0016783	sulfurtransferase activity(GO:0016783)
0.3	1.4	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.3	0.3	GO:0000404	heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.3	1.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.3	1.0	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.3	1.3	GO:0016979	lipoate-protein ligase activity(GO:0016979)
0.3	0.7	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.3	1.0	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.3	3.6	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.3	2.6	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.3	3.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3	2.0	GO:0003796	lysozyme activity(GO:0003796)
0.3	1.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3	0.3	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3	0.6	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.3	3.5	GO:0098505	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.3	2.8	GO:0019211	phosphatase activator activity(GO:0019211)
0.3	17.9	GO:0003954	NADH dehydrogenase activity(GO:0003954)
0.3	1.9	GO:0042296	ISG15 transferase activity(GO:0042296)
0.3	9.6	GO:0004527	exonuclease activity(GO:0004527)
0.3	1.9	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3	3.1	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.3	0.6	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.3	0.9	GO:0045504	dynein heavy chain binding(GO:0045504)
0.3	1.5	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.3	1.5	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.3	20.2	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.3	1.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.3	0.9	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3	8.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.3	2.7	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.3	0.9	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.3	10.0	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.3	0.9	GO:0097677	STAT family protein binding(GO:0097677)
0.3	0.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.3	1.5	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.3	0.9	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
0.3	3.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.3	2.2	GO:0004064	arylesterase activity(GO:0004064)
0.3	0.8	GO:0019961	interferon binding(GO:0019961)
0.3	5.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.3	8.4	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.3	6.9	GO:0070182	DNA polymerase binding(GO:0070182)
0.3	0.5	GO:0070568	guanylyltransferase activity(GO:0070568)
0.3	1.9	GO:0043208	glycosphingolipid binding(GO:0043208)
0.3	0.5	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.3	1.3	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.3	0.5	GO:0000403	Y-form DNA binding(GO:0000403)
0.3	1.1	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3	1.6	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.3	1.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.3	1.3	GO:0032452	histone demethylase activity(GO:0032452)
0.3	1.3	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.2	4.7	GO:0070628	proteasome binding(GO:0070628)
0.2	1.0	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.2	5.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.2	0.7	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2	1.0	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2	1.7	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.2	3.7	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.2	0.5	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2	0.5	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2	6.7	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2	1.4	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.2	0.5	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2	4.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	1.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.2	0.2	GO:0002134	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.2	3.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	3.5	GO:0031996	thioesterase binding(GO:0031996)
0.2	1.4	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.2	1.1	GO:0035242	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2	2.7	GO:0089720	caspase binding(GO:0089720)
0.2	3.3	GO:0043295	glutathione binding(GO:0043295)
0.2	0.4	GO:0048256	flap endonuclease activity(GO:0048256)
0.2	0.6	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225)
0.2	2.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2	1.7	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	3.4	GO:0070513	death domain binding(GO:0070513)
0.2	1.5	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2	0.2	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2	0.2	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.2	1.4	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2	1.0	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2	8.3	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.2	1.6	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.2	0.6	GO:0003916	DNA topoisomerase activity(GO:0003916)
0.2	0.6	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.2	0.4	GO:0030332	cyclin binding(GO:0030332)
0.2	1.6	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.2	2.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.2	1.8	GO:0034452	dynactin binding(GO:0034452)
0.2	1.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2	1.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.2	0.8	GO:0052827	inositol pentakisphosphate phosphatase activity(GO:0052827)
0.2	4.5	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.2	0.2	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2	0.6	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2	3.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.2	0.8	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.2	1.4	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.2	0.8	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	0.6	GO:0004905	type I interferon receptor activity(GO:0004905)
0.2	0.6	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2	1.0	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2	0.6	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.2	2.6	GO:0042809	vitamin D receptor binding(GO:0042809)
0.2	0.6	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.2	1.7	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.2	1.7	GO:1901612	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.2	0.7	GO:0034046	poly(G) binding(GO:0034046)
0.2	4.6	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.2	5.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.2	1.1	GO:0023025	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.2	0.6	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2	1.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.2	1.8	GO:0070034	telomerase RNA binding(GO:0070034)
0.2	0.5	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.2	1.4	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	8.4	GO:0050681	androgen receptor binding(GO:0050681)
0.2	1.2	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.2	1.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.2	0.7	GO:0004803	transposase activity(GO:0004803)
0.2	6.1	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2	4.2	GO:0017091	AU-rich element binding(GO:0017091)
0.2	0.7	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.2	0.5	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.2	1.5	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.2	0.3	GO:0032143	single thymine insertion binding(GO:0032143)
0.2	2.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.2	1.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.2	0.5	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	0.5	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2	5.1	GO:0000049	tRNA binding(GO:0000049)
0.2	3.9	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	0.6	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2	0.6	GO:0043515	kinetochore binding(GO:0043515)
0.2	3.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2	1.8	GO:0016209	antioxidant activity(GO:0016209)
0.2	2.5	GO:0004526	ribonuclease P activity(GO:0004526)
0.2	1.1	GO:0031491	nucleosome binding(GO:0031491)
0.2	0.8	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2	0.6	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2	0.5	GO:0005047	signal recognition particle binding(GO:0005047)
0.2	0.2	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.2	0.2	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.2	4.6	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2	0.6	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	0.4	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.1	0.4	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	3.8	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	2.2	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.6	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.4	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.7	GO:0004771	sterol esterase activity(GO:0004771)
0.1	21.3	GO:0042393	histone binding(GO:0042393)
0.1	0.9	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.4	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1	0.6	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.1	0.6	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	0.3	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.1	1.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1	0.6	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1	3.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	0.7	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.3	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.1	4.7	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	0.7	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	1.4	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.5	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.7	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	3.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.1	2.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.5	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.1	0.3	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.4	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1	2.4	GO:0005537	mannose binding(GO:0005537)
0.1	2.2	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.4	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	1.7	GO:0051011	microtubule minus-end binding(GO:0051011)
0.1	26.4	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	4.1	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	2.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	3.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	1.3	GO:0048156	tau protein binding(GO:0048156)
0.1	0.9	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.6	GO:0070728	leucine binding(GO:0070728)
0.1	0.6	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1	0.4	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.1	1.3	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	9.0	GO:0051082	unfolded protein binding(GO:0051082)
0.1	0.4	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.4	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1	0.6	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	1.5	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	0.5	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.6	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	0.3	GO:0097100	supercoiled DNA binding(GO:0097100)
0.1	1.5	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.3	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	0.2	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.3	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	0.7	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.7	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.6	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.5	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.3	GO:0046527	glucosyltransferase activity(GO:0046527)
0.1	0.5	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	1.5	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	0.6	GO:1990446	U1 snRNP binding(GO:1990446)
0.1	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	2.0	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.4	GO:0042731	PH domain binding(GO:0042731)
0.1	0.4	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1	1.2	GO:0019843	rRNA binding(GO:0019843)
0.1	0.8	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.3	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.3	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	10.5	GO:0031072	heat shock protein binding(GO:0031072)
0.1	1.0	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	1.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.3	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.3	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1	0.9	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1	0.1	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	0.8	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.1	1.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.6	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	2.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	5.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	1.4	GO:0043495	protein anchor(GO:0043495)
0.1	0.8	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	0.8	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.1	2.4	GO:0050699	WW domain binding(GO:0050699)
0.1	0.4	GO:0004998	transferrin receptor activity(GO:0004998)
0.1	0.3	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.1	0.3	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	0.4	GO:0008410	CoA-transferase activity(GO:0008410)
0.1	0.3	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1	0.3	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	0.6	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	3.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.1	1.0	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.1	0.3	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	0.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.5	GO:0030145	manganese ion binding(GO:0030145)
0.1	0.5	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	0.4	GO:0000700	mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1	0.7	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.1	0.3	GO:0043559	insulin binding(GO:0043559)
0.1	0.9	GO:0001614	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.1	6.8	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1	0.3	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	6.5	GO:0003777	microtubule motor activity(GO:0003777)
0.1	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	5.1	GO:0003682	chromatin binding(GO:0003682)
0.1	0.4	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.1	3.1	GO:0030507	spectrin binding(GO:0030507)
0.1	0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.2	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.1	0.5	GO:0017018	myosin phosphatase activity(GO:0017018)
0.1	0.3	GO:0033265	choline binding(GO:0033265)
0.1	0.4	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1	0.2	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.1	1.3	GO:0043531	ADP binding(GO:0043531)
0.1	0.9	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.3	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	1.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.9	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.2	GO:0016594	glycine binding(GO:0016594)
0.1	0.4	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	1.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.5	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.3	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	0.2	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.1	0.6	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	1.1	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	1.0	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.2	GO:0035276	ethanol binding(GO:0035276)
0.1	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.5	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.2	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.1	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	0.5	GO:0009374	biotin binding(GO:0009374)
0.1	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	1.0	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	1.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.5	GO:0015232	heme transporter activity(GO:0015232)
0.1	1.9	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.3	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.3	GO:0008518	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1	2.1	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1	0.2	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.9	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.1	0.5	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.5	GO:1990239	steroid hormone binding(GO:1990239)
0.1	0.5	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.2	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1	1.5	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	2.9	GO:0042169	SH2 domain binding(GO:0042169)
0.1	0.5	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.2	GO:0019003	GDP binding(GO:0019003)
0.1	0.9	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.1	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.1	0.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.8	GO:0005123	death receptor binding(GO:0005123)
0.1	0.2	GO:0008378	galactosyltransferase activity(GO:0008378) UDP-galactosyltransferase activity(GO:0035250)
0.1	0.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.1	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.1	2.1	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	5.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.1	0.7	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	0.2	GO:1904408	dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1	10.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.1	0.3	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.2	GO:0017136	NAD-dependent histone deacetylase activity(GO:0017136)
0.1	0.5	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	3.1	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	0.6	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	3.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.1	0.3	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.1	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.6	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1	0.3	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	0.5	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.9	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	3.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	0.3	GO:0015926	glucosidase activity(GO:0015926)
0.1	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.1	0.2	GO:0061659	ubiquitin-like protein ligase activity(GO:0061659)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.2	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.1	GO:0017111	nucleoside-triphosphatase activity(GO:0017111)
0.1	115.9	GO:0003677	DNA binding(GO:0003677)
0.1	1.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.3	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1	0.4	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.2	GO:0035197	siRNA binding(GO:0035197)
0.1	0.8	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.1	GO:0004672	protein kinase activity(GO:0004672)
0.1	0.3	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.9	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.2	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1	2.5	GO:0003924	GTPase activity(GO:0003924)
0.1	0.9	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1	0.8	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1	0.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	2.0	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	0.8	GO:0042605	peptide antigen binding(GO:0042605)
0.0	1.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.9	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.8	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	1.2	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.6	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.2	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.5	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	1.1	GO:0031489	myosin V binding(GO:0031489)
0.0	0.9	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.5	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.3	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	1.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.3	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361) sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.6	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.0	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.4	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	1.3	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
0.0	0.2	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0	0.4	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.2	GO:0070404	NADH binding(GO:0070404)
0.0	0.7	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.2	GO:0035198	miRNA binding(GO:0035198)
0.0	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.2	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.5	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.3	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0	0.5	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.4	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	0.4	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.3	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	36.0	GO:0003676	nucleic acid binding(GO:0003676)
0.0	0.4	GO:0045502	dynein binding(GO:0045502)
0.0	0.8	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.2	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.6	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.4	GO:0031433	telethonin binding(GO:0031433)
0.0	0.8	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0004040	amidase activity(GO:0004040)
0.0	0.5	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	1.1	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0	0.1	GO:0033149	FFAT motif binding(GO:0033149)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.3	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0	0.4	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.0	0.1	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.2	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.3	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	0.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.4	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.3	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.1	GO:0032451	demethylase activity(GO:0032451)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0031711	angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0	0.5	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0004114	cyclic-nucleotide phosphodiesterase activity(GO:0004112) 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0018636	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	1.0	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.5	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0015250	water channel activity(GO:0015250)
0.0	0.1	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.3	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.0	GO:0005057	receptor signaling protein activity(GO:0005057)
0.0	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.3	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.1	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.0	1.2	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.0	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.0	GO:0005549	odorant binding(GO:0005549)
0.0	0.1	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.0	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.0	0.0	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	0.0	GO:0016595	glutamate binding(GO:0016595)
0.0	0.0	GO:0019107	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.0	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	14.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.6	5.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	2.7	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.2	4.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	2.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	4.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	1.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	6.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	3.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	4.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	2.1	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.1	0.9	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	4.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	6.7	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	1.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.8	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.8	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	1.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	1.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	1.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	3.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	6.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	3.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	2.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	6.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	2.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	3.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	1.0	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	0.3	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.1	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	3.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.3	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	0.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	1.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	1.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	1.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.7	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.1	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	2.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.6	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.1	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	0.5	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.6	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.2	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.6	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	1.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.8	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	34.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	1.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.3	2.0	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3	3.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	0.5	PID S1P S1P2 PATHWAY	S1P2 pathway
0.2	3.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	10.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	7.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.2	9.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.2	0.5	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	2.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.2	0.5	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	8.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	13.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	5.0	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	4.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	3.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	7.0	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	3.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	0.5	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	0.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	1.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	0.7	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.1	1.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	0.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	1.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	3.5	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	2.6	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	0.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	2.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	3.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	1.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	4.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	1.7	PID ATM PATHWAY	ATM pathway
0.1	2.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	3.0	PID BCR 5PATHWAY	BCR signaling pathway
0.1	1.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	1.0	PID ATR PATHWAY	ATR signaling pathway
0.1	0.5	PID EPO PATHWAY	EPO signaling pathway
0.1	1.6	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	6.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	1.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.5	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	1.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.6	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.6	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	1.0	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.8	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.7	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.9	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.6	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	1.1	PID FOXO PATHWAY	FoxO family signaling
0.0	1.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.9	PID E2F PATHWAY	E2F transcription factor network
0.0	0.9	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.2	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.0	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.6	PID FGF PATHWAY	FGF signaling pathway
0.0	0.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	1.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	2.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.7	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2	0.9	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.2	0.5	GO:0016662	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2	0.6	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.1	0.4	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.6	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	1.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.3	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1	0.8	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	0.4	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.1	0.3	GO:0050405	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1	0.5	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	1.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	3.7	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.1	1.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.5	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	1.1	GO:0016918	retinal binding(GO:0016918)
0.1	0.7	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.2	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	0.5	GO:0016530	metallochaperone activity(GO:0016530)
0.1	0.2	GO:0052835	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1	0.2	GO:0030984	kininogen binding(GO:0030984)
0.1	1.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	1.4	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	0.2	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.1	0.2	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	0.3	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	1.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.4	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.3	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.1	GO:0015117	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0	0.1	GO:0004797	thymidine kinase activity(GO:0004797)
0.0	0.5	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0	0.3	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.2	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0	0.1	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.1	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.3	GO:0016015	morphogen activity(GO:0016015)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.3	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.4	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.5	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0	0.8	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.1	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.2	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0052796	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	1.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.8	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.2	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.5	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.6	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.7	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.5	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.2	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.0	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.0	0.1	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.0	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.0	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.3	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.9	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.2	4.8	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.2	1.2	GO:1902227	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
1.1	4.3	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.9	3.6	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.7	3.6	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.7	3.5	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.6	3.7	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.6	3.0	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6	4.1	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.5	1.6	GO:0002316	follicular B cell differentiation(GO:0002316) activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.5	4.7	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4	1.3	GO:0071284	cellular response to lead ion(GO:0071284)
0.4	1.7	GO:0006203	dGTP catabolic process(GO:0006203)
0.4	5.8	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3	2.4	GO:0032596	T cell antigen processing and presentation(GO:0002457) protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.3	1.7	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.3	1.6	GO:2000845	testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.3	1.0	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.3	0.3	GO:0021997	neural plate axis specification(GO:0021997)
0.3	1.1	GO:0032053	ciliary basal body organization(GO:0032053)
0.3	1.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.3	0.8	GO:0072434	signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.3	1.0	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.3	1.3	GO:0033590	response to cobalamin(GO:0033590)
0.3	1.8	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.3	2.5	GO:1904424	regulation of GTP binding(GO:1904424)
0.3	1.0	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2	1.0	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.2	0.7	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.2	1.2	GO:0048539	bone marrow development(GO:0048539)
0.2	2.9	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.2	1.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.2	1.3	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.2	2.1	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2	1.0	GO:0051941	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.2	0.8	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.2	1.2	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2	0.8	GO:0015808	L-alanine transport(GO:0015808)
0.2	1.8	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2	0.8	GO:0030242	pexophagy(GO:0030242)
0.2	1.0	GO:0046203	spermidine catabolic process(GO:0046203)
0.2	3.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.2	0.4	GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.2	3.0	GO:0051639	actin filament network formation(GO:0051639)
0.2	0.4	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.2	0.9	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	2.4	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.2	1.3	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2	3.4	GO:0051014	actin filament severing(GO:0051014)
0.2	0.7	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.2	0.2	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2	0.5	GO:0001300	chronological cell aging(GO:0001300)
0.2	0.9	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.2	0.2	GO:0032241	positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.2	0.5	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	0.7	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.2	1.7	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	0.5	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.2	0.5	GO:1903939	negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.2	4.8	GO:0097242	beta-amyloid clearance(GO:0097242)
0.2	1.0	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.2	0.6	GO:2000313	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2	0.9	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.2	0.6	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2	2.6	GO:0035855	megakaryocyte development(GO:0035855)
0.1	3.3	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	3.0	GO:0097320	membrane tubulation(GO:0097320)
0.1	0.4	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.1	0.6	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1	0.9	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.1	0.4	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.1	1.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.4	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	0.4	GO:0032887	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1	3.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.6	GO:0044375	regulation of peroxisome size(GO:0044375)
0.1	0.4	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.1	0.4	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.4	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	1.5	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	0.4	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
0.1	0.6	GO:0042631	cellular response to water deprivation(GO:0042631)
0.1	0.4	GO:0072709	cellular response to sorbitol(GO:0072709)
0.1	1.6	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1	0.8	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	1.0	GO:0016926	protein desumoylation(GO:0016926)
0.1	0.2	GO:1903626	positive regulation of DNA catabolic process(GO:1903626)
0.1	1.2	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	0.4	GO:0038178	complement component C5a signaling pathway(GO:0038178)
0.1	0.4	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	1.7	GO:0072697	protein localization to cell cortex(GO:0072697)
0.1	0.6	GO:0035900	response to isolation stress(GO:0035900)
0.1	0.1	GO:0007041	lysosomal transport(GO:0007041)
0.1	4.7	GO:0042554	superoxide anion generation(GO:0042554)
0.1	1.6	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.1	0.3	GO:0061010	gall bladder development(GO:0061010)
0.1	0.3	GO:0072200	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1	0.3	GO:0021896	forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	0.3	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1	0.5	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.1	0.3	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.1	0.5	GO:2000232	regulation of rRNA processing(GO:2000232)
0.1	1.2	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.4	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.4	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1	0.3	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.1	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	0.4	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.5	GO:1903044	protein localization to membrane raft(GO:1903044)
0.1	2.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	0.7	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.1	9.7	GO:0042100	B cell proliferation(GO:0042100)
0.1	0.8	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.1	0.3	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1	2.6	GO:0006625	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1	1.4	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.3	GO:0012502	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1	0.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	1.0	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1	0.3	GO:0044878	cleavage furrow formation(GO:0036089) mitotic cytokinesis checkpoint(GO:0044878)
0.1	0.8	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.4	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	1.0	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.1	1.5	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.1	0.5	GO:0003014	renal system process(GO:0003014)
0.1	1.6	GO:0035641	locomotory exploration behavior(GO:0035641)
0.1	2.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	1.4	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.1	1.1	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.1	0.3	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.1	1.3	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.1	0.5	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.1	0.5	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.3	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.2	GO:0018283	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1	0.8	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.1	0.3	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1	5.6	GO:0030183	B cell differentiation(GO:0030183)
0.1	0.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	0.1	GO:0035330	regulation of hippo signaling(GO:0035330)
0.1	0.5	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.1	1.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.4	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	1.3	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.5	GO:0071569	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	0.3	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1	0.1	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.1	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.1	0.6	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.2	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1	0.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1	0.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.3	GO:0016333	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1	0.3	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	0.3	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	1.1	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	0.5	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1	0.4	GO:0046543	thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.1	0.6	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.3	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.1	0.9	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1	0.5	GO:0006013	mannose metabolic process(GO:0006013)
0.1	0.2	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	0.2	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1	0.7	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.5	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	0.5	GO:0046325	negative regulation of glucose import(GO:0046325)
0.1	0.1	GO:0000189	MAPK import into nucleus(GO:0000189)
0.1	0.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.1	0.2	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.7	GO:0071285	cellular response to lithium ion(GO:0071285)
0.1	0.2	GO:0019086	late viral transcription(GO:0019086)
0.1	0.6	GO:0042118	endothelial cell activation(GO:0042118)
0.1	4.2	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.2	GO:2000535	regulation of entry of bacterium into host cell(GO:2000535)
0.1	0.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.1	GO:0090182	negative regulation of pinocytosis(GO:0048550) regulation of secretion of lysosomal enzymes(GO:0090182)
0.1	1.0	GO:0071361	cellular response to ethanol(GO:0071361)
0.1	0.5	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.0	GO:2000538	negative regulation of T cell cytokine production(GO:0002725) T-helper 1 cell activation(GO:0035711) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0	2.0	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	1.3	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.3	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	1.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.2	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.2	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.5	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.5	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.2	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.0	0.1	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.6	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	5.7	GO:0007338	single fertilization(GO:0007338)
0.0	0.4	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.1	GO:0045766	positive regulation of angiogenesis(GO:0045766)
0.0	0.1	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.1	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	1.1	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	1.0	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.6	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	1.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.2	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0	5.3	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.0	0.1	GO:1904529	regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0	1.2	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.4	GO:0051601	exocyst localization(GO:0051601)
0.0	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	1.5	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.5	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.8	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.6	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.1	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.0	0.6	GO:0048011	neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0	0.5	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0	0.6	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.8	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.5	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.7	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.5	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	1.1	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.0	GO:0072079	nephron tubule formation(GO:0072079)
0.0	0.3	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.6	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.1	GO:1901796	regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.1	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.0	0.7	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.4	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	1.6	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.3	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	1.0	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	1.2	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.1	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.2	GO:0060242	contact inhibition(GO:0060242)
0.0	0.3	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.4	GO:0006516	N-acetylglucosamine metabolic process(GO:0006044) glycoprotein catabolic process(GO:0006516)
0.0	0.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.9	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.4	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0051697	protein delipidation(GO:0051697)
0.0	0.0	GO:0046619	optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.0	0.1	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	1.9	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0061110	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.2	GO:0001967	suckling behavior(GO:0001967)
0.0	0.7	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.3	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.3	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0	0.1	GO:0007568	aging(GO:0007568)
0.0	0.3	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.0	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0	0.4	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.3	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.0	0.3	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0	0.3	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.0	0.1	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.0	0.7	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.3	GO:0010155	regulation of proton transport(GO:0010155)
0.0	1.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.0	0.3	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.1	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.0	0.4	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0043132	NAD transport(GO:0043132)
0.0	0.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.5	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.1	GO:0044804	nucleophagy(GO:0044804)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	1.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.2	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	1.5	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0	0.1	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.3	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	0.2	GO:0022900	electron transport chain(GO:0022900)
0.0	0.4	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.3	GO:0016082	synaptic vesicle priming(GO:0016082)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.2	GO:0010669	epithelial structure maintenance(GO:0010669)
0.0	0.2	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.8	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.1	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.0	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.2	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.1	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.0	0.2	GO:0070932	histone H3 deacetylation(GO:0070932)
0.0	0.1	GO:0007584	response to nutrient(GO:0007584)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0046794	transport of virus(GO:0046794) intracellular transport of virus(GO:0075733)
0.0	0.0	GO:1903061	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0	0.4	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.1	GO:0031929	TOR signaling(GO:0031929)
0.0	0.5	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.2	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	0.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.0	GO:1903039	positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.3	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043281)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.3	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.0	0.2	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.3	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.4	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0003096	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.8	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.1	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0	0.0	GO:2000508	regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.1	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	0.8	GO:0051289	protein homotetramerization(GO:0051289)
0.0	0.2	GO:0035666	TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0	0.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.1	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.5	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	1.1	GO:1990745	EARP complex(GO:1990745)
0.2	0.7	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.2	0.6	GO:0005607	laminin-2 complex(GO:0005607)
0.2	0.5	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.2	1.8	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.2	1.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.4	GO:0071020	post-spliceosomal complex(GO:0071020)
0.1	0.4	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	1.6	GO:0043203	axon hillock(GO:0043203)
0.1	0.5	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0055028	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.1	0.4	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.7	GO:0032807	DNA ligase IV complex(GO:0032807)
0.1	0.8	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.4	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	1.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.5	GO:0070435	Shc-EGFR complex(GO:0070435)
0.1	0.3	GO:0032044	DSIF complex(GO:0032044)
0.1	2.3	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.2	GO:0019034	viral replication complex(GO:0019034)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.2	GO:1902636	kinociliary basal body(GO:1902636)
0.1	0.4	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.8	GO:0016600	flotillin complex(GO:0016600)
0.1	1.7	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.0	0.2	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0	0.3	GO:0071817	MMXD complex(GO:0071817)
0.0	0.7	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:1902560	GMP reductase complex(GO:1902560)
0.0	0.4	GO:0097443	sorting endosome(GO:0097443)
0.0	0.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	1.1	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.3	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	2.4	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.2	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.4	GO:0000124	SAGA complex(GO:0000124)
0.0	0.3	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.5	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.6	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:1990037	Lewy body core(GO:1990037)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.9	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	1.5	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.2	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.3	GO:0035749	myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219)
0.0	2.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0032302	MutSbeta complex(GO:0032302)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	1.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.2	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.0	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.0	GO:1990031	pinceau fiber(GO:1990031)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.2	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.2	GO:0043235	receptor complex(GO:0043235)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	28.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	7.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	3.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	4.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.7	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	1.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	1.3	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.9	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.9	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.3	GO:0004998	transferrin receptor activity(GO:0004998)
0.4	1.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.3	1.1	GO:0004074	biliverdin reductase activity(GO:0004074)
0.2	1.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.2	0.8	GO:0043515	kinetochore binding(GO:0043515)
0.2	0.9	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.2	0.7	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2	0.5	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2	0.8	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2	1.0	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2	0.5	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.2	0.5	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.1	1.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	0.6	GO:0047718	indanol dehydrogenase activity(GO:0047718)
0.1	1.1	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.8	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	1.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.6	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	1.4	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.3	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1	0.3	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	0.4	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1	1.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	0.5	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	0.4	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.1	0.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.7	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	0.2	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1	1.1	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.1	0.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	1.0	GO:0016405	CoA-ligase activity(GO:0016405)
0.1	0.9	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.4	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	0.3	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1	0.4	GO:0000182	rDNA binding(GO:0000182)
0.1	0.4	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	0.6	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.2	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.4	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.4	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	1.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	1.1	GO:0001848	complement binding(GO:0001848)
0.0	0.3	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.0	0.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.2	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.2	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.7	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	1.3	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.2	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.3	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	2.7	GO:0005507	copper ion binding(GO:0005507)
0.0	0.3	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.1	GO:0004040	amidase activity(GO:0004040)
0.0	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.9	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.7	GO:0070628	proteasome binding(GO:0070628)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.3	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.9	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.5	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0019862	IgA binding(GO:0019862)
0.0	0.3	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	3.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.6	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.2	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0004819	glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0	0.6	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0097016	L27 domain binding(GO:0097016)
0.0	1.6	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.4	GO:0043495	protein anchor(GO:0043495)
0.0	0.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.5	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	1.0	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.7	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.3	GO:0070513	death domain binding(GO:0070513)
0.0	0.3	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	2.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0080130	L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.6	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.2	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.2	GO:0042171	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.3	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.4	1.1	GO:0005960	glycine cleavage complex(GO:0005960)
0.3	3.9	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3	1.9	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.3	1.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.3	0.8	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.3	1.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	1.0	GO:0033186	CAF-1 complex(GO:0033186)
0.2	0.6	GO:0030689	Noc complex(GO:0030689)
0.2	1.3	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.2	1.9	GO:0005638	lamin filament(GO:0005638)
0.2	1.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2	1.3	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	1.0	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2	1.0	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.2	1.1	GO:0070545	PeBoW complex(GO:0070545)
0.2	2.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.2	0.7	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2	0.7	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.2	0.7	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.2	1.3	GO:0070552	BRISC complex(GO:0070552)
0.1	1.9	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.6	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	1.0	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.4	GO:0019034	viral replication complex(GO:0019034)
0.1	1.0	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	2.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.4	GO:0097447	dendritic tree(GO:0097447)
0.1	0.8	GO:0044326	dendritic spine neck(GO:0044326)
0.1	0.6	GO:0001740	Barr body(GO:0001740)
0.1	0.9	GO:0071439	clathrin complex(GO:0071439)
0.1	0.7	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.4	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	0.1	GO:0034455	t-UTP complex(GO:0034455)
0.1	0.5	GO:0043196	varicosity(GO:0043196)
0.1	1.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.5	GO:0016272	prefoldin complex(GO:0016272)
0.1	0.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	1.1	GO:0030686	90S preribosome(GO:0030686)
0.1	0.3	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.1	0.5	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.3	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	3.0	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	1.5	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.3	GO:0071817	MMXD complex(GO:0071817)
0.1	1.6	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.6	GO:0032156	septin cytoskeleton(GO:0032156)
0.1	0.3	GO:0033503	HULC complex(GO:0033503)
0.1	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.3	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.1	0.3	GO:0030905	retromer, tubulation complex(GO:0030905)
0.1	0.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.2	GO:0005846	nuclear cap binding complex(GO:0005846)
0.1	0.2	GO:0045273	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	1.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.2	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.6	GO:0045120	pronucleus(GO:0045120)
0.0	0.3	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.1	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0	0.2	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.0	0.0	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0	0.7	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.2	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0	0.6	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.9	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	1.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.8	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.3	GO:0005827	polar microtubule(GO:0005827)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.4	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.4	GO:0000243	commitment complex(GO:0000243)
0.0	0.5	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.4	GO:0001741	XY body(GO:0001741)
0.0	0.7	GO:0034709	methylosome(GO:0034709)
0.0	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.2	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.2	GO:1990584	cardiac Troponin complex(GO:1990584)
0.0	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	1.6	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	0.2	GO:0005816	equatorial microtubule organizing center(GO:0000923) spindle pole body(GO:0005816)
0.0	0.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.0	1.3	GO:0030118	clathrin coat(GO:0030118)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.7	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.4	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.4	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.6	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.3	GO:0016580	Sin3 complex(GO:0016580)
0.0	1.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0097422	retromer, cargo-selective complex(GO:0030906) tubular endosome(GO:0097422)
0.0	0.1	GO:0071159	NF-kappaB complex(GO:0071159)
0.0	0.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.4	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	1.5	GO:0016459	myosin complex(GO:0016459)
0.0	2.7	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.8	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.6	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.0	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	1.3	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	5.7	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.0	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.7	GO:0015030	Cajal body(GO:0015030)
0.0	1.8	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.4	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.1	GO:0008021	synaptic vesicle(GO:0008021)
0.0	0.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	3.0	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.8	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	3.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.8	10.5	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5	1.6	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.5	2.6	GO:0042289	MHC class II protein binding(GO:0042289)
0.5	1.9	GO:0050473	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.4	2.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3	4.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.3	1.9	GO:0005499	vitamin D binding(GO:0005499)
0.3	0.9	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.3	3.3	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.3	1.8	GO:1990254	keratin filament binding(GO:1990254)
0.3	1.9	GO:0070492	oligosaccharide binding(GO:0070492)
0.3	1.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	0.7	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	0.7	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2	0.7	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.2	0.6	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2	2.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	4.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.2	1.9	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.2	0.5	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2	3.1	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.2	0.5	GO:0051185	FAD transmembrane transporter activity(GO:0015230) coenzyme transporter activity(GO:0051185)
0.1	0.7	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	0.4	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.1	1.0	GO:0045159	myosin II binding(GO:0045159)
0.1	0.9	GO:0016015	morphogen activity(GO:0016015)
0.1	5.5	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.7	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	2.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.6	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	3.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	1.5	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	7.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.3	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1	2.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.4	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.1	0.4	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	1.9	GO:0071837	HMG box domain binding(GO:0071837)
0.1	2.0	GO:0005523	tropomyosin binding(GO:0005523)
0.1	1.7	GO:0004697	protein kinase C activity(GO:0004697)
0.1	6.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	1.0	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.4	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.1	0.3	GO:0033265	choline binding(GO:0033265)
0.1	1.0	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	1.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.8	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.4	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.9	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	1.4	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.4	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.9	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	1.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	1.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	4.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.3	GO:0015266	protein channel activity(GO:0015266)
0.0	1.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.4	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	1.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.6	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.2	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.0	0.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	1.5	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.5	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	3.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.3	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.9	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	3.2	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	1.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.6	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
1.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	2.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	1.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	1.6	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.1	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	11.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	6.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4	10.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4	3.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	9.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	3.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	5.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	12.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	0.7	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	1.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	2.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	3.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.5	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	1.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	1.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.8	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.7	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	2.0	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	1.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.9	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.5	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	1.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.8	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	3.7	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.3	4.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	2.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	9.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	3.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	2.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	2.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.8	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	2.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.6	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	2.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	2.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.9	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	10.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	1.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	2.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	3.6	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.7	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.8	PID ALK1 PATHWAY	ALK1 signaling events
0.0	2.4	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	4.5	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	1.3	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.9	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	1.5	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	2.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	13.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	9.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	4.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	4.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	3.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	6.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.8	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	7.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	3.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	2.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
1.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.5	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.3	0.8	GO:0021558	midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) regulation of timing of neuron differentiation(GO:0060164)
0.3	2.0	GO:0008218	bioluminescence(GO:0008218)
0.2	0.8	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.1	0.6	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.1	1.5	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.3	GO:0071109	superior temporal gyrus development(GO:0071109)
0.1	0.4	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.1	0.2	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.1	0.6	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1	0.1	GO:0035483	gastric motility(GO:0035482) gastric emptying(GO:0035483)
0.1	0.2	GO:0036269	swimming behavior(GO:0036269)
0.0	0.4	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.0	0.1	GO:0019046	release from viral latency(GO:0019046)
0.0	0.3	GO:0043129	surfactant homeostasis(GO:0043129)
0.0	0.1	GO:0043449	olfactory learning(GO:0008355) cellular alkene metabolic process(GO:0043449)
0.0	0.2	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
0.0	0.6	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.4	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:0048686	regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0	0.7	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.2	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0001550	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0	0.0	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) synaptic transmission involved in micturition(GO:0060084)
0.0	0.9	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.6	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.2	GO:0090520	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.9	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	1.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	3.1	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	2.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.8	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.5	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	2.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	1.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.9	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	14.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	2.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	1.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	2.2	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	2.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.9	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	3.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.3	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.5	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.7	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID EPO PATHWAY	EPO signaling pathway
0.0	1.0	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.6	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.5	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.7	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	18.7	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.4	10.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	13.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	2.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	4.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	3.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	3.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	3.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	3.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	2.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	7.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.7	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	2.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.7	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	2.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.0	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	5.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME SIGNALING BY NOTCH	Genes involved in Signaling by NOTCH
0.0	1.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	1.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.8	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.9	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	2.1	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	19.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.1	3.3	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
1.1	3.2	GO:0008859	exoribonuclease II activity(GO:0008859)
1.0	6.3	GO:0019238	cyclohydrolase activity(GO:0019238)
1.0	3.9	GO:0004047	aminomethyltransferase activity(GO:0004047)
1.0	2.9	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.9	3.8	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.9	3.5	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.8	2.5	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.8	3.3	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.8	0.8	GO:0045118	azole transporter activity(GO:0045118)
0.8	4.6	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.7	5.3	GO:0034711	inhibin binding(GO:0034711)
0.7	5.3	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.6	4.5	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.6	3.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.6	3.0	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.6	2.4	GO:0004998	transferrin receptor activity(GO:0004998)
0.6	1.8	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.6	3.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.6	12.0	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.6	30.6	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.5	1.6	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.5	1.6	GO:0070283	lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.5	1.6	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.5	7.0	GO:0038132	neuregulin binding(GO:0038132)
0.5	1.6	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5	1.5	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.5	7.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5	1.5	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
0.5	2.9	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.5	1.5	GO:0047726	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.5	3.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.5	1.9	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.5	1.9	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.5	1.9	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.5	2.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.5	3.7	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.5	1.4	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.4	1.3	GO:0032551	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.4	1.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.4	2.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.4	1.3	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.4	1.3	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.4	1.2	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.4	3.3	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.4	1.2	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.4	1.9	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.4	5.3	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.4	1.9	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.4	2.2	GO:0030492	hemoglobin binding(GO:0030492)
0.4	1.5	GO:0019862	IgA binding(GO:0019862)
0.4	1.8	GO:0004771	sterol esterase activity(GO:0004771)
0.4	0.7	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3	2.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.3	2.4	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.3	1.7	GO:0070404	NADH binding(GO:0070404)
0.3	3.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.3	0.7	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.3	4.3	GO:0015926	glucosidase activity(GO:0015926)
0.3	1.3	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.3	1.0	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.3	4.5	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.3	1.6	GO:0061665	SUMO ligase activity(GO:0061665)
0.3	1.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3	2.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3	1.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.3	1.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3	1.6	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3	3.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.3	1.8	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3	2.4	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.3	2.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.3	1.8	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3	0.9	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.3	0.9	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3	0.9	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.3	0.9	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3	1.1	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.3	2.0	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3	2.8	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3	1.1	GO:0071253	connexin binding(GO:0071253)
0.3	3.6	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3	1.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.3	1.8	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.3	1.6	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.3	1.3	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.3	2.8	GO:0051525	NFAT protein binding(GO:0051525)
0.2	0.7	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.2	2.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.2	1.4	GO:0009378	four-way junction helicase activity(GO:0009378)
0.2	1.2	GO:0030151	molybdenum ion binding(GO:0030151)
0.2	0.2	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2	4.9	GO:0032794	GTPase activating protein binding(GO:0032794)
0.2	0.9	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.2	1.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2	0.7	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.2	0.7	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2	1.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.2	3.1	GO:0005243	gap junction channel activity(GO:0005243)
0.2	1.6	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.2	0.7	GO:0052593	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2	1.5	GO:0008142	oxysterol binding(GO:0008142)
0.2	0.7	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.2	4.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.2	3.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.2	2.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2	1.7	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.2	0.6	GO:0015235	cobalamin transporter activity(GO:0015235)
0.2	0.8	GO:0017040	ceramidase activity(GO:0017040)
0.2	0.6	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.2	0.6	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
0.2	0.6	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.2	1.0	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2	1.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	0.8	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.2	2.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.2	0.6	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.2	0.8	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.2	1.8	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	0.6	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2	0.8	GO:0016841	ammonia-lyase activity(GO:0016841)
0.2	1.4	GO:0001515	opioid peptide activity(GO:0001515)
0.2	4.5	GO:0001056	RNA polymerase III activity(GO:0001056)
0.2	1.4	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2	3.1	GO:0031996	thioesterase binding(GO:0031996)
0.2	0.6	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2	0.8	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.2	1.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.2	0.6	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.2	1.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2	1.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.2	1.1	GO:0046979	TAP2 binding(GO:0046979)
0.2	0.4	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.2	4.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.2	1.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2	9.2	GO:0042169	SH2 domain binding(GO:0042169)
0.2	0.7	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2	0.5	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2	1.6	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2	0.9	GO:0004905	type I interferon receptor activity(GO:0004905)
0.2	0.9	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.2	1.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.2	0.7	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2	1.4	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2	6.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.2	2.9	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.2	0.8	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.2	0.2	GO:0004673	protein histidine kinase activity(GO:0004673)
0.2	1.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.2	0.8	GO:0032395	MHC class II receptor activity(GO:0032395)
0.2	0.5	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.2	0.5	GO:0070728	leucine binding(GO:0070728)
0.2	0.6	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.2	1.8	GO:0097016	L27 domain binding(GO:0097016)
0.2	0.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.2	0.5	GO:0034191	apolipoprotein receptor binding(GO:0034190) apolipoprotein A-I receptor binding(GO:0034191)
0.2	3.8	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.2	2.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.2	1.7	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2	3.0	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2	0.6	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.7	GO:0034046	poly(G) binding(GO:0034046)
0.1	1.5	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.1	GO:0050405	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1	0.7	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	0.9	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.1	3.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.9	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	0.4	GO:0015141	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) succinate transmembrane transporter activity(GO:0015141)
0.1	0.3	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	6.5	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	1.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	0.7	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	0.6	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1	0.4	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1	1.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0097259	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1	0.3	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1	5.4	GO:0050699	WW domain binding(GO:0050699)
0.1	0.8	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.6	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1	0.4	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.1	0.5	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	1.4	GO:0010181	FMN binding(GO:0010181)
0.1	0.6	GO:0070905	serine binding(GO:0070905)
0.1	0.8	GO:0036310	annealing helicase activity(GO:0036310)
0.1	0.5	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	1.5	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	5.0	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.4	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.4	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1	0.5	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.5	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	0.6	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	2.2	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.2	GO:0034511	U3 snoRNA binding(GO:0034511)
0.1	0.9	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.2	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1	0.4	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.1	0.7	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.9	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	9.6	GO:0030165	PDZ domain binding(GO:0030165)
0.1	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.1	1.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1	1.8	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.9	GO:1901612	cardiolipin binding(GO:1901612)
0.1	0.8	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	0.8	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	0.5	GO:0047298	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1	5.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	3.3	GO:0001848	complement binding(GO:0001848)
0.1	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.6	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.7	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1	1.2	GO:0035004	phosphatidylinositol 3-kinase activity(GO:0035004)
0.1	0.6	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.1	1.5	GO:0016594	glycine binding(GO:0016594)
0.1	1.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	1.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.4	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	1.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	1.7	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.3	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	1.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	0.4	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.6	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.6	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	0.5	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.3	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.1	3.9	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	0.5	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	1.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.5	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	1.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1	0.5	GO:0004368	glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.3	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.1	0.4	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.1	0.4	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1	0.7	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	1.0	GO:0015232	heme transporter activity(GO:0015232)
0.1	1.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	1.9	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1	1.0	GO:0030883	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1	1.1	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	3.0	GO:0042605	peptide antigen binding(GO:0042605)
0.1	0.5	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.2	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	1.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.5	GO:0070008	serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.1	0.6	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1	0.3	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.3	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1	0.3	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.1	1.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	1.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	1.9	GO:0008301	DNA binding, bending(GO:0008301)
0.1	0.3	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.3	GO:0005333	norepinephrine transmembrane transporter activity(GO:0005333)
0.1	0.4	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	1.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.3	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	1.8	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.6	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.5	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.7	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.4	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.2	GO:0032090	Pyrin domain binding(GO:0032090)
0.1	2.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1	0.2	GO:0031177	phosphopantetheine binding(GO:0031177)
0.1	1.9	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.4	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	2.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	1.4	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.5	GO:1903135	cupric ion binding(GO:1903135)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.7	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.2	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.3	GO:0015350	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1	0.5	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	1.0	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.1	0.5	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	1.6	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1	3.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.8	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.2	GO:0030984	kininogen binding(GO:0030984)
0.1	1.6	GO:0031005	filamin binding(GO:0031005)
0.1	0.1	GO:0005174	CD40 receptor binding(GO:0005174)
0.1	0.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.4	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	0.6	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1	0.2	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	1.0	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.4	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	1.1	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	0.8	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	1.6	GO:0002162	dystroglycan binding(GO:0002162)
0.1	5.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1	0.4	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.1	1.0	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.1	0.3	GO:0035473	lipase binding(GO:0035473)
0.1	0.1	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	0.6	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	0.7	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	1.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	1.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.1	0.3	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.6	GO:0042608	T cell receptor binding(GO:0042608)
0.1	2.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	1.0	GO:0031014	troponin T binding(GO:0031014)
0.1	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	0.1	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.5	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.7	GO:0032027	myosin light chain binding(GO:0032027)
0.1	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.3	GO:0042019	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1	0.5	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	1.5	GO:0070403	NAD+ binding(GO:0070403)
0.1	0.8	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.3	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	1.1	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.1	0.5	GO:0043426	MRF binding(GO:0043426)
0.1	0.3	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	1.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	2.1	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.2	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	0.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.5	GO:0019863	IgE binding(GO:0019863)
0.1	1.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	1.2	GO:0051400	BH domain binding(GO:0051400)
0.1	0.3	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.3	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.1	0.2	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1	0.6	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1	0.4	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	1.0	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	2.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	1.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.6	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	1.1	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.3	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	0.2	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	0.9	GO:0019843	rRNA binding(GO:0019843)
0.1	0.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.4	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.1	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.7	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.6	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1	0.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.2	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	1.0	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.1	1.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.2	GO:0098809	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1	0.1	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.1	0.4	GO:0016416	O-palmitoyltransferase activity(GO:0016416)
0.1	0.9	GO:0030552	cAMP binding(GO:0030552)
0.1	0.3	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.2	GO:0038025	reelin receptor activity(GO:0038025)
0.1	0.4	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	1.1	GO:0051183	vitamin transporter activity(GO:0051183)
0.1	0.2	GO:0004040	amidase activity(GO:0004040)
0.1	0.1	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.1	0.5	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.2	GO:0032093	SAM domain binding(GO:0032093)
0.1	0.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.7	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	2.8	GO:0005518	collagen binding(GO:0005518)
0.1	1.0	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.2	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	5.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	2.3	GO:0008374	O-acyltransferase activity(GO:0008374)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.7	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	0.2	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	1.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	1.5	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.1	0.1	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1	0.1	GO:0034618	arginine binding(GO:0034618)
0.1	0.5	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.2	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1	5.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.5	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.5	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.8	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.0	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.0	GO:0005310	dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0	0.4	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	3.5	GO:0019003	GDP binding(GO:0019003)
0.0	1.3	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	1.0	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.2	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0	0.2	GO:0098960	postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0	1.0	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.4	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	2.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.3	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	1.8	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.3	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.5	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.3	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0	0.2	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.1	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	1.1	GO:0031420	alkali metal ion binding(GO:0031420)
0.0	4.0	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.1	GO:0052895	norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.0	0.2	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.3	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	3.1	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.3	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.0	0.3	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.6	GO:0016878	acid-thiol ligase activity(GO:0016878)
0.0	3.3	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.7	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.4	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.3	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.8	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0052844	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0	0.2	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.0	0.3	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.5	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.7	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.3	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.1	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.8	GO:0005123	death receptor binding(GO:0005123)
0.0	0.9	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.0	0.7	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.2	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.8	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.1	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.2	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.1	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.5	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.6	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	2.2	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.8	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.8	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.3	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.3	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.9	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	0.2	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.2	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.9	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.3	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.3	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0	0.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.9	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.3	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.9	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	1.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.4	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.4	GO:0031489	myosin V binding(GO:0031489)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	1.2	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0016635	succinate dehydrogenase (ubiquinone) activity(GO:0008177) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.2	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.1	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.0	0.4	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	1.6	GO:0015108	chloride transmembrane transporter activity(GO:0015108)
0.0	0.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.1	GO:0090556	apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	5.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0099609	microtubule lateral binding(GO:0099609)
0.0	0.4	GO:0005537	mannose binding(GO:0005537)
0.0	1.1	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.2	GO:0005057	receptor signaling protein activity(GO:0005057)
0.0	0.2	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.3	GO:0019864	IgG binding(GO:0019864)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	3.4	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0003916	DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0	1.4	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0016775	creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0	0.1	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0	0.2	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	1.9	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.3	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.0	GO:0071949	FAD binding(GO:0071949)
0.0	0.1	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.4	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	0.7	GO:0042805	actinin binding(GO:0042805)
0.0	0.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.0	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.0	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.0	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)
0.0	0.0	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.0	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508) 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0	0.4	GO:0043621	protein self-association(GO:0043621)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.5	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.5	GO:0004519	endonuclease activity(GO:0004519)
0.0	0.2	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.0	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0	0.2	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	1.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.3	GO:0002317	plasma cell differentiation(GO:0002317)
1.1	3.2	GO:0033364	mast cell secretory granule organization(GO:0033364)
1.1	3.2	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.0	14.4	GO:0015671	oxygen transport(GO:0015671)
0.9	3.7	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.8	3.4	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.7	5.0	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.7	2.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.7	7.0	GO:0001955	blood vessel maturation(GO:0001955)
0.6	2.5	GO:0042418	epinephrine biosynthetic process(GO:0042418)
0.6	2.4	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.6	7.2	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5	3.3	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.5	1.6	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5	1.6	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.5	3.2	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.5	1.6	GO:0060584	nitric oxide transport(GO:0030185) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5	4.6	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.5	2.8	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.5	1.4	GO:0046521	sphingoid catabolic process(GO:0046521)
0.3	1.0	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.3	1.7	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.3	1.0	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.3	3.4	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.3	1.3	GO:0071461	cellular response to redox state(GO:0071461)
0.3	9.6	GO:0015695	organic cation transport(GO:0015695)
0.3	0.9	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3	1.1	GO:0002215	defense response to nematode(GO:0002215)
0.3	2.3	GO:0035799	ureter maturation(GO:0035799)
0.3	0.3	GO:0070602	regulation of centromeric sister chromatid cohesion(GO:0070602)
0.2	1.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648) regulation of determination of dorsal identity(GO:2000015)
0.2	2.1	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.2	0.7	GO:0007518	myoblast fate determination(GO:0007518)
0.2	0.7	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.2	1.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.2	0.4	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.2	1.1	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2	0.8	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.2	0.9	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.2	2.2	GO:0046325	negative regulation of glucose import(GO:0046325)
0.2	4.7	GO:0006337	nucleosome disassembly(GO:0006337)
0.2	0.5	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2	0.6	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.2	0.6	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.2	2.5	GO:0051639	actin filament network formation(GO:0051639)
0.2	1.2	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.1	1.5	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.1	3.8	GO:0006825	copper ion transport(GO:0006825)
0.1	0.3	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1	0.5	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.4	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1	0.4	GO:0044179	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1	1.3	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	2.1	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.1	0.9	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1	0.7	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.4	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	0.4	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.7	GO:0090235	regulation of metaphase plate congression(GO:0090235)
0.1	2.7	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.5	GO:1902613	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1	0.8	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.1	0.8	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.1	0.5	GO:0080009	mRNA methylation(GO:0080009)
0.1	0.3	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1	0.3	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	2.2	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.5	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.3	GO:0008050	female courtship behavior(GO:0008050)
0.1	0.2	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1	0.3	GO:0048075	positive regulation of eye pigmentation(GO:0048075)
0.1	0.4	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.1	0.4	GO:0045726	regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1	3.9	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	1.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	3.8	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.1	0.4	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.7	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.1	0.7	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	1.0	GO:0021702	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1	1.3	GO:0034378	chylomicron assembly(GO:0034378)
0.1	1.3	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.1	1.0	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.4	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
0.1	0.7	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.3	GO:0048867	stem cell fate determination(GO:0048867)
0.1	0.3	GO:0035711	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1	0.2	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) regulation of progesterone biosynthetic process(GO:2000182)
0.1	0.8	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.2	GO:1904729	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.1	0.2	GO:0034227	tRNA thio-modification(GO:0034227)
0.1	1.2	GO:0002003	angiotensin maturation(GO:0002003)
0.1	0.4	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.1	0.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.4	GO:0015866	adenine transport(GO:0015853) ADP transport(GO:0015866)
0.1	0.3	GO:0072660	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	1.3	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.5	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.3	GO:0006581	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1	0.4	GO:0015886	heme transport(GO:0015886)
0.1	1.9	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.1	0.5	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
0.1	0.1	GO:0090346	cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1	0.5	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.5	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.1	0.7	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.6	GO:0042023	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.1	0.2	GO:0097212	cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
0.1	0.5	GO:0001505	regulation of neurotransmitter levels(GO:0001505)
0.1	0.3	GO:0060215	primitive hemopoiesis(GO:0060215)
0.1	0.1	GO:1900195	positive regulation of oocyte maturation(GO:1900195)
0.1	0.5	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1	1.0	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.1	0.3	GO:0006196	AMP catabolic process(GO:0006196)
0.1	0.2	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.1	0.5	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	3.7	GO:0060135	maternal process involved in female pregnancy(GO:0060135)
0.0	0.6	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.7	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0	1.3	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.2	GO:0032383	dolichol metabolic process(GO:0019348) regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	1.0	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.4	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:2000291	myoblast proliferation(GO:0051450) regulation of myoblast proliferation(GO:2000291)
0.0	0.1	GO:0071344	diphosphate metabolic process(GO:0071344)
0.0	0.2	GO:0051105	regulation of DNA ligation(GO:0051105)
0.0	0.4	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0	0.2	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	1.1	GO:0048665	neuron fate specification(GO:0048665)
0.0	0.3	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.4	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.2	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.3	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.8	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.0	0.7	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.4	GO:0019079	viral genome replication(GO:0019079)
0.0	0.2	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.2	GO:0060613	fat pad development(GO:0060613)
0.0	0.3	GO:1904044	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0	0.2	GO:0086097	renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0	0.2	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
0.0	0.2	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.3	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.7	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.0	0.1	GO:0001694	histamine biosynthetic process(GO:0001694)
0.0	0.2	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.2	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.4	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.4	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.4	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	2.4	GO:0006695	cholesterol biosynthetic process(GO:0006695)
0.0	0.7	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	1.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	5.2	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.1	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0	0.3	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.2	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.0	0.8	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.1	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.3	GO:0001764	neuron migration(GO:0001764)
0.0	0.3	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.9	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.2	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:0061107	seminal vesicle development(GO:0061107)
0.0	0.4	GO:0051255	spindle midzone assembly(GO:0051255)
0.0	0.3	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.0	0.8	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.2	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.7	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.9	GO:0045143	homologous chromosome segregation(GO:0045143)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	2.3	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	0.5	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.0	0.4	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.6	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.4	GO:0002643	regulation of tolerance induction(GO:0002643)
0.0	0.6	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.1	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.3	GO:0046349	N-acetylglucosamine metabolic process(GO:0006044) amino sugar biosynthetic process(GO:0046349)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.5	GO:2000272	negative regulation of receptor activity(GO:2000272)
0.0	0.2	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.2	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.9	GO:0042417	dopamine metabolic process(GO:0042417)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.8	GO:0042407	cristae formation(GO:0042407)
0.0	0.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of resting membrane potential(GO:0060075)
0.0	0.1	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	3.5	GO:0051028	mRNA transport(GO:0051028)
0.0	0.5	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.3	GO:0034776	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0	0.7	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.9	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0051607	defense response to virus(GO:0051607)
0.0	0.1	GO:1903817	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.2	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.4	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0	1.5	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.1	GO:0098856	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.2	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	1.1	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.3	GO:0007050	cell cycle arrest(GO:0007050)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.7	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	2.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	3.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	1.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.2	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	2.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	3.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	3.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.7	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	0.9	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.8	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.7	3.3	GO:1902904	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.6	2.5	GO:0002317	plasma cell differentiation(GO:0002317)
0.6	2.4	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6	4.2	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.5	3.4	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5	1.9	GO:0031394	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of platelet-derived growth factor production(GO:0090362) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.5	1.4	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.5	4.6	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.4	1.2	GO:0035989	tendon development(GO:0035989)
0.4	3.1	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.4	2.3	GO:0033029	regulation of neutrophil apoptotic process(GO:0033029)
0.4	3.4	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.3	1.8	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.3	0.9	GO:1900158	negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3	2.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3	1.0	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.3	2.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.2	1.7	GO:0089700	protein kinase D signaling(GO:0089700)
0.2	3.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2	1.0	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2	2.4	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2	0.7	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2	1.1	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.2	1.0	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2	0.9	GO:0070980	biphenyl catabolic process(GO:0070980)
0.2	1.5	GO:0002051	osteoblast fate commitment(GO:0002051)
0.2	0.5	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.2	2.8	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.2	0.5	GO:0043132	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.1	0.4	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1	0.9	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	0.9	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.4	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1	0.8	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	0.4	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.9	GO:0048014	Tie signaling pathway(GO:0048014)
0.1	0.9	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	3.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	6.1	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.1	0.4	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
0.1	0.5	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.1	0.6	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	1.4	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.3	GO:0071109	superior temporal gyrus development(GO:0071109)
0.1	0.7	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.1	0.7	GO:0003344	pericardium morphogenesis(GO:0003344)
0.1	0.4	GO:0034334	adherens junction maintenance(GO:0034334)
0.1	3.0	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	1.7	GO:0008228	opsonization(GO:0008228)
0.1	0.7	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	6.9	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	1.5	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.2	GO:2000439	monocyte extravasation(GO:0035696) negative regulation of eosinophil activation(GO:1902567) regulation of monocyte extravasation(GO:2000437) positive regulation of monocyte extravasation(GO:2000439)
0.1	0.9	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.4	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.7	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.7	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	1.5	GO:0035855	megakaryocyte development(GO:0035855)
0.1	1.9	GO:0042359	vitamin D metabolic process(GO:0042359)
0.1	0.2	GO:0035606	induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.1	0.6	GO:0009249	protein lipoylation(GO:0009249)
0.1	0.4	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.5	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	0.2	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	0.7	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.4	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.1	0.6	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.2	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	0.4	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.2	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.7	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	1.0	GO:0043586	tongue development(GO:0043586)
0.0	1.7	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.5	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.3	GO:0097688	AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0	0.2	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.4	GO:0045955	regulation of SNARE complex assembly(GO:0035542) negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0	0.7	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.2	GO:0021824	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
0.0	0.4	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.2	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	3.7	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	9.1	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.4	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	1.2	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.3	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.6	GO:0044849	estrous cycle(GO:0044849)
0.0	0.4	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.7	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0	2.8	GO:0070268	cornification(GO:0070268)
0.0	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0	1.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:2000332	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.1	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0	4.0	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	2.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.7	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	0.4	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.2	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	0.4	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.0	GO:0070166	enamel mineralization(GO:0070166)
0.0	1.9	GO:0050821	protein stabilization(GO:0050821)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.7	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	4.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	5.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	2.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	3.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.3	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.7	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.9	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	1.2	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.5	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	1.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	3.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	16.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	8.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.2	4.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	2.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	3.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	5.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	6.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	1.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	3.0	PID ALK1 PATHWAY	ALK1 signaling events
0.1	2.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	2.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	15.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	4.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	2.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	5.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	2.8	PID FOXO PATHWAY	FoxO family signaling
0.1	1.5	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	1.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	2.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	2.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.4	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.3	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.6	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.2	ST GAQ PATHWAY	G alpha q Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	3.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	0.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	0.8	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	2.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	2.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	12.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.6	10.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.6	6.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4	23.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	12.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.3	3.8	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.3	7.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.3	1.0	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.2	15.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	3.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	10.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	6.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	5.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	2.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	9.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.2	0.8	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	4.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	3.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	3.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	3.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	2.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.9	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	1.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	8.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	1.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	1.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.6	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	2.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	2.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	1.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	0.7	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	6.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.0	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	7.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	0.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	2.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	1.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.0	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.7	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	3.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.7	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	2.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.9	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	2.1	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	1.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	2.0	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	1.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	0.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	3.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.3	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	1.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.6	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	2.0	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	1.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.1	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	1.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	1.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	3.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	3.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	1.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.1	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.2	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	3.0	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.6	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.8	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	1.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	1.2	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.7	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.0	REACTOME PHOSPHOLIPASE C MEDIATED CASCADE	Genes involved in Phospholipase C-mediated cascade
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.2	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.6	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.9	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.5	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	26.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.9	25.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.7	16.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6	31.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.6	5.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	23.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.5	39.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4	16.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.4	1.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.4	14.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.4	10.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	8.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.3	6.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.3	3.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	1.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	4.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	4.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	6.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.2	3.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	3.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	1.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	2.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	4.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	5.0	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.2	3.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	0.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	4.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	1.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.9	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	13.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	6.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	14.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	2.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	5.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	2.6	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	1.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	4.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	0.6	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	1.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	1.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.9	REACTOME METABOLISM OF MRNA	Genes involved in Metabolism of mRNA
0.1	2.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.9	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	0.9	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	1.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.4	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	2.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.6	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	1.4	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	1.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	1.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.0	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.0	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	15.1	GO:0045095	keratin filament(GO:0045095)
0.2	0.7	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.2	1.8	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	1.0	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.7	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.1	0.5	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1	0.3	GO:0031251	PAN complex(GO:0031251)
0.1	0.3	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.1	0.4	GO:0031501	mannosyltransferase complex(GO:0031501)
0.1	2.4	GO:0030057	desmosome(GO:0030057)
0.1	0.8	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	0.4	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.2	GO:0070557	PCNA-p21 complex(GO:0070557)
0.1	0.3	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.5	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	0.4	GO:0031415	NatA complex(GO:0031415)
0.1	0.5	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.2	GO:0018444	translation release factor complex(GO:0018444)
0.1	0.2	GO:0042587	glycogen granule(GO:0042587)
0.1	2.5	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.1	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.2	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.5	GO:0000800	lateral element(GO:0000800)
0.0	1.1	GO:0001533	cornified envelope(GO:0001533)
0.0	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.5	GO:0031209	SCAR complex(GO:0031209)
0.0	0.4	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0034657	GID complex(GO:0034657)
0.0	0.6	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.3	GO:0033010	paranodal junction(GO:0033010)
0.0	0.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	1.4	GO:0097542	ciliary tip(GO:0097542)
0.0	0.1	GO:0030689	Noc complex(GO:0030689)
0.0	0.1	GO:0060187	cell pole(GO:0060187)
0.0	0.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.7	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.3	GO:0042555	MCM complex(GO:0042555)
0.0	0.4	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.4	GO:0090543	Flemming body(GO:0090543)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	1.0	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.1	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.0	2.5	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	2.6	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.4	GO:0031082	BLOC complex(GO:0031082)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	1.8	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	1.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.2	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.1	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0035370	UBC13-UEV1A complex(GO:0035370)
0.0	0.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.3	GO:0042629	mast cell granule(GO:0042629)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	4.2	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	1.7	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	2.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.7	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	6.3	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	2.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	2.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	3.6	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.3	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.6	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	6.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
1.5	7.5	GO:0016403	dimethylargininase activity(GO:0016403)
1.1	5.3	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1	0.3	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	0.6	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	2.8	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.4	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.9	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.3	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1	0.5	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1	3.6	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1	0.5	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0019862	IgA binding(GO:0019862)
0.1	0.3	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	1.5	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.7	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.2	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	0.6	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	1.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.7	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.8	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.8	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	2.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	3.0	GO:0005178	integrin binding(GO:0005178)
0.0	1.6	GO:0000149	SNARE binding(GO:0000149)
0.0	2.2	GO:0005496	steroid binding(GO:0005496)
0.0	0.3	GO:0031005	filamin binding(GO:0031005)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.2	GO:0016405	CoA-ligase activity(GO:0016405)
0.0	3.2	GO:0005516	calmodulin binding(GO:0005516)
0.0	0.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0008327	methyl-CpG binding(GO:0008327)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.7	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.2	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	3.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	2.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	1.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	3.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	2.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	1.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.4	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.8	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	2.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	13.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	7.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	2.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	4.0	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	5.8	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	1.7	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	2.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	3.3	REACTOME KINESINS	Genes involved in Kinesins
0.1	3.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	2.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	4.9	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	2.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	3.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	2.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	2.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	0.8	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	5.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.9	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	1.9	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.7	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.8	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.9	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	1.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	1.2	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	1.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	2.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	3.9	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	2.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.3	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	4.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.6	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.6	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	1.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.5	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.0	0.3	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.9	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	4.2	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.5	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.0	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME SIGNALING BY FGFR IN DISEASE	Genes involved in Signaling by FGFR in disease
0.0	0.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	6.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	1.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	2.1	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.5	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	2.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	3.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	4.4	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	1.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	1.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	3.1	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	7.4	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.2	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	2.8	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	1.4	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	1.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	2.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	0.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	1.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	1.0	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	3.2	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.7	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	1.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.6	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	5.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.5	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	2.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.7	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.2	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	1.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	2.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	2.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME BIOLOGICAL OXIDATIONS	Genes involved in Biological oxidations
0.0	0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	3.0	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.0	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.9	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	1.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	2.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.6	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.2	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.2	0.9	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	0.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	1.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1	0.2	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.3	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	0.5	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.3	GO:0050294	steroid sulfotransferase activity(GO:0050294)
0.0	0.2	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.3	GO:0043426	MRF binding(GO:0043426)
0.0	1.0	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	3.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.5	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.4	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.5	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.3	GO:0000150	recombinase activity(GO:0000150)
0.0	0.1	GO:0052595	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0	0.1	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.2	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.1	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	0.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.0	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	13.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	4.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	6.4	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	4.2	PID ARF6 PATHWAY	Arf6 signaling events
0.1	4.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	3.8	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	3.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	3.9	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	1.4	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.6	PID ALK2 PATHWAY	ALK2 signaling events
0.0	1.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	1.0	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.5	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.0	PID BMP PATHWAY	BMP receptor signaling
0.0	0.3	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.5	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.0	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	12.6	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.7	16.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.5	4.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4	7.7	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.4	8.9	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.4	7.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.4	5.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.3	5.9	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3	10.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3	1.7	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.3	7.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	7.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.3	8.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3	11.2	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.3	30.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.3	8.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	9.7	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.2	6.3	REACTOME KINESINS	Genes involved in Kinesins
0.2	3.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2	6.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	5.9	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.2	3.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	3.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	1.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	16.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	2.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.2	7.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	2.5	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2	1.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	6.4	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2	3.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	6.1	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.2	6.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2	4.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	7.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	1.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	4.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	10.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	5.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	10.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	2.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	2.4	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	3.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	5.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	6.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	4.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.5	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1	1.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	0.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.9	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.1	0.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	6.6	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	2.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	0.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	0.8	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	1.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	5.4	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1	1.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	11.6	REACTOME TRANSLATION	Genes involved in Translation
0.1	2.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	2.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	1.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	1.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	1.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	3.0	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.6	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	0.7	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	2.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	1.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	4.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.9	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.6	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	2.4	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	5.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	7.6	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.7	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.5	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.4	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	5.6	GO:0097179	protease inhibitor complex(GO:0097179)
0.8	16.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.7	10.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.7	4.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.5	4.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.5	1.9	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.5	3.2	GO:0019815	B cell receptor complex(GO:0019815)
0.4	1.2	GO:0071751	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.4	2.4	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
0.4	2.3	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.4	4.1	GO:0042611	MHC protein complex(GO:0042611)
0.4	16.9	GO:0042571	immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.3	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.3	2.8	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3	0.8	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2	0.2	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.2	2.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	1.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	1.2	GO:0030870	Mre11 complex(GO:0030870)
0.2	1.2	GO:0044326	dendritic spine neck(GO:0044326)
0.2	3.3	GO:0001891	phagocytic cup(GO:0001891)
0.2	1.1	GO:0036021	endolysosome lumen(GO:0036021)
0.2	0.5	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2	1.2	GO:0032010	phagolysosome(GO:0032010)
0.1	0.6	GO:0000811	GINS complex(GO:0000811)
0.1	0.9	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.1	0.7	GO:0036398	TCR signalosome(GO:0036398)
0.1	0.1	GO:0030315	T-tubule(GO:0030315)
0.1	0.6	GO:0005923	bicellular tight junction(GO:0005923)
0.1	0.1	GO:0071437	invadopodium(GO:0071437)
0.1	0.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.1	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1	0.5	GO:0031905	early endosome lumen(GO:0031905)
0.1	1.9	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.8	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	0.4	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	0.4	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.1	0.6	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	0.5	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	0.4	GO:0005712	chiasma(GO:0005712)
0.1	3.9	GO:0042629	mast cell granule(GO:0042629)
0.1	0.5	GO:0001652	granular component(GO:0001652)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.3	GO:1990298	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1	0.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.1	GO:0000805	X chromosome(GO:0000805)
0.1	2.3	GO:0071564	npBAF complex(GO:0071564)
0.1	0.4	GO:1990075	periciliary membrane compartment(GO:1990075)
0.1	0.8	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.3	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.1	0.6	GO:0042825	TAP complex(GO:0042825)
0.1	0.4	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.4	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1	0.3	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	1.3	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	0.1	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.1	0.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.3	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
0.1	0.2	GO:0043159	acrosomal matrix(GO:0043159)
0.1	0.5	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	0.4	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.1	0.7	GO:0000125	PCAF complex(GO:0000125)
0.1	0.3	GO:0070382	exocytic vesicle(GO:0070382)
0.1	0.2	GO:0005960	glycine cleavage complex(GO:0005960)
0.1	0.7	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.1	0.2	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	0.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	3.4	GO:0001772	immunological synapse(GO:0001772)
0.1	0.6	GO:0000796	condensin complex(GO:0000796)
0.1	0.5	GO:0097486	multivesicular body lumen(GO:0097486)
0.1	0.4	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.2	GO:0060187	cell pole(GO:0060187)
0.1	0.2	GO:1990462	omegasome(GO:1990462)
0.1	0.4	GO:0035976	AP1 complex(GO:0035976)
0.1	0.5	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.4	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.2	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.3	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	0.2	GO:0034455	t-UTP complex(GO:0034455)
0.1	0.1	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.1	0.1	GO:0000502	proteasome complex(GO:0000502)
0.1	0.4	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	0.2	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	0.6	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.1	GO:0032009	early phagosome(GO:0032009)
0.1	0.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.8	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	0.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.1	0.2	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.3	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.1	GO:0030427	site of polarized growth(GO:0030427)
0.1	0.1	GO:0016528	sarcoplasm(GO:0016528)
0.1	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.6	GO:0097433	dense body(GO:0097433)
0.1	0.3	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1	0.9	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0	0.2	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.2	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.2	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.9	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.3	GO:0051286	cell tip(GO:0051286)
0.0	0.7	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	12.8	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.3	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0055087	Ski complex(GO:0055087)
0.0	0.5	GO:0071953	elastic fiber(GO:0071953)
0.0	0.8	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.5	GO:0042555	MCM complex(GO:0042555)
0.0	1.0	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	0.0	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	2.8	GO:0015030	Cajal body(GO:0015030)
0.0	0.2	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.0	0.2	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.3	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.2	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	0.3	GO:0000322	storage vacuole(GO:0000322)
0.0	0.6	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.3	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.0	0.1	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.0	0.4	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	1.1	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.3	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	1.2	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.3	GO:0061617	MICOS complex(GO:0061617)
0.0	0.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0	0.6	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	1.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.5	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.7	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.0	0.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.3	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.1	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.0	2.4	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.1	GO:1990031	pinceau fiber(GO:1990031)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.3	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.3	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.4	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0005771	multivesicular body(GO:0005771)
0.0	0.4	GO:0044447	axoneme part(GO:0044447)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	0.7	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	2.6	GO:0035579	specific granule membrane(GO:0035579)
0.0	1.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0005873	plus-end kinesin complex(GO:0005873)
0.0	0.1	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.0	0.2	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.2	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0031213	RSF complex(GO:0031213)
0.0	0.3	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.4	GO:0097227	sperm annulus(GO:0097227)
0.0	0.5	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.2	GO:0031105	septin complex(GO:0031105)
0.0	0.2	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.5	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0	0.3	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.4	GO:0000145	exocyst(GO:0000145)
0.0	3.5	GO:0001650	fibrillar center(GO:0001650)
0.0	0.8	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.0	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.3	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.0	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0032420	stereocilium(GO:0032420)
0.0	0.4	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.5	GO:0031904	endosome lumen(GO:0031904)
0.0	0.0	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.0	GO:0072534	perineuronal net(GO:0072534)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	3.9	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.7	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.1	GO:0036128	CatSper complex(GO:0036128)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	1.6	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.6	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0002081	outer acrosomal membrane(GO:0002081)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.4	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.0	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.0	0.7	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.1	GO:0097255	R2TP complex(GO:0097255)
0.0	0.1	GO:0032302	MutSbeta complex(GO:0032302)
0.0	0.4	GO:0030120	vesicle coat(GO:0030120)
0.0	0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.0	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.7	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.0	GO:0071546	pi-body(GO:0071546)
0.0	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.3	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.0	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
0.0	0.1	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0	0.4	GO:0032982	myosin filament(GO:0032982)
0.0	1.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.7	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.0	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.0	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.4	GO:0035869	ciliary transition zone(GO:0035869)
0.0	1.8	GO:0055037	recycling endosome(GO:0055037)
0.0	0.0	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.0	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.0	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.0	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.3	GO:1990391	DNA repair complex(GO:1990391)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	5.1	GO:0016607	nuclear speck(GO:0016607)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.2	GO:0005657	replication fork(GO:0005657)
0.0	0.2	GO:0005871	kinesin complex(GO:0005871)
0.0	0.5	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	3.3	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.0	GO:0005846	nuclear cap binding complex(GO:0005846)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.9	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.0	GO:0097447	dendritic tree(GO:0097447)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.6	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.0	0.9	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	2.0	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.2	0.6	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.2	0.6	GO:0019981	interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) interleukin-6 binding(GO:0019981)
0.2	0.9	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1	0.4	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.4	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	0.5	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	1.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036) sphingolipid binding(GO:0046625)
0.1	1.1	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.6	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	1.2	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	1.3	GO:0048019	receptor antagonist activity(GO:0048019)
0.1	0.3	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.1	0.3	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.2	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1	0.2	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	3.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.6	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1	0.2	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.1	0.7	GO:0045159	myosin II binding(GO:0045159)
0.1	0.3	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.7	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	1.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.9	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0031877	somatostatin receptor binding(GO:0031877)
0.0	1.3	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	1.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.4	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.4	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.8	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.3	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.3	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.7	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	2.5	GO:0019843	rRNA binding(GO:0019843)
0.0	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.4	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0	0.7	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:1901474	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) azole transmembrane transporter activity(GO:1901474)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.7	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.3	GO:0035197	siRNA binding(GO:0035197)
0.0	0.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	0.1	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	0.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	1.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.0	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.0	0.4	GO:0060089	receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0	0.6	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.1	GO:0001851	complement component C3b binding(GO:0001851)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	4.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	0.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	3.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	2.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	2.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	0.7	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.7	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	2.9	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	1.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.4	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	1.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	2.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	2.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.0	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	3.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	1.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	4.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.9	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	5.8	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	1.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	2.3	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	2.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	2.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	3.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	2.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.5	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	8.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	4.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	3.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	2.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	1.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	0.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	1.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.9	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.7	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	2.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.8	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.1	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.4	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.1	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	26.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2	3.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	3.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	2.2	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	0.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.0	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	2.8	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	2.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.3	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	16.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	1.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	1.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.5	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.1	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	2.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.7	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.9	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0004998	transferrin receptor activity(GO:0004998)
0.1	0.6	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	0.3	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	0.3	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.1	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.0	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0	0.1	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	0.4	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.3	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.0	GO:0035473	lipase binding(GO:0035473)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	13.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	15.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	0.4	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1	3.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	2.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	2.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	3.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	2.0	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	2.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.8	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	0.7	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	0.8	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	4.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.6	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	2.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	0.4	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1	1.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	0.6	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	3.9	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.9	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	0.4	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	1.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.6	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.6	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	1.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	1.1	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.9	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.1	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.4	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.6	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.2	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.5	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.2	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
1.0	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
2.1	REACTOME SIGNALING BY ILS	Genes involved in Signaling by Interleukins

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.8	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
1.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	4.7	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.4	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	1.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	2.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1	2.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	5.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	3.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	1.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	1.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	2.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.4	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	0.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.0	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	2.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	1.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	1.3	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	2.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	1.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	0.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	0.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.8	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	1.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	3.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	1.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	4.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	4.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.0	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	1.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.0	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.7	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.4	REACTOME SYNTHESIS OF DNA	Genes involved in Synthesis of DNA
0.0	1.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	1.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	2.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	1.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	2.0	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	0.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	1.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	7.3	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	1.5	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.6	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.7	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	2.3	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	2.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.0	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	3.3	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.9	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.0	0.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.8	26.4	GO:0008859	exoribonuclease II activity(GO:0008859)
5.3	31.6	GO:0042296	ISG15 transferase activity(GO:0042296)
3.5	34.5	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
3.2	19.2	GO:0046979	TAP2 binding(GO:0046979)
2.8	13.9	GO:0004771	sterol esterase activity(GO:0004771)
2.4	7.2	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
1.9	56.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.9	22.5	GO:0031386	protein tag(GO:0031386)
1.8	12.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.6	8.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
1.6	9.5	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
1.4	11.3	GO:0070087	chromo shadow domain binding(GO:0070087)
1.4	42.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
1.2	6.2	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
1.2	2.5	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
1.1	7.8	GO:0061133	endopeptidase activator activity(GO:0061133)
1.1	8.7	GO:0004000	adenosine deaminase activity(GO:0004000)
1.1	6.4	GO:0004614	phosphoglucomutase activity(GO:0004614)
1.0	3.0	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.0	6.9	GO:0070492	oligosaccharide binding(GO:0070492)
1.0	4.8	GO:0042289	MHC class II protein binding(GO:0042289)
1.0	5.7	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.9	4.6	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.9	8.9	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.9	3.5	GO:0005151	interleukin-1, Type II receptor binding(GO:0005151)
0.8	19.7	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.7	4.4	GO:0008948	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.7	5.0	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.7	3.5	GO:0047820	D-glutamate cyclase activity(GO:0047820)
0.6	1.9	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.6	6.2	GO:1990380	Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.6	4.8	GO:0031996	thioesterase binding(GO:0031996)
0.6	7.6	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6	3.9	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.5	15.9	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.5	3.5	GO:0001515	opioid peptide activity(GO:0001515)
0.5	3.9	GO:0019863	IgE binding(GO:0019863)
0.5	8.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.5	21.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.5	13.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4	9.9	GO:0000339	RNA cap binding(GO:0000339)
0.4	2.7	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.4	2.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.4	2.5	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4	1.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.4	8.1	GO:0051400	BH domain binding(GO:0051400)
0.4	4.2	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4	4.5	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.3	0.7	GO:0032767	copper-dependent protein binding(GO:0032767)
0.3	1.3	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3	1.6	GO:0051425	PTB domain binding(GO:0051425)
0.3	34.9	GO:0003727	single-stranded RNA binding(GO:0003727)
0.3	0.9	GO:0001069	regulatory region RNA binding(GO:0001069)
0.3	81.9	GO:0001047	core promoter binding(GO:0001047)
0.3	1.2	GO:0097001	ceramide binding(GO:0097001)
0.3	0.9	GO:0010997	anaphase-promoting complex binding(GO:0010997) phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3	5.9	GO:0070628	proteasome binding(GO:0070628)
0.3	26.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.3	8.5	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3	10.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.3	4.9	GO:0005522	profilin binding(GO:0005522)
0.3	16.3	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.3	4.6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3	0.5	GO:0050692	DBD domain binding(GO:0050692)
0.3	10.4	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2	1.2	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.2	5.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	3.0	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.2	1.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.2	0.6	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.2	1.8	GO:1901612	cardiolipin binding(GO:1901612)
0.2	1.2	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.2	1.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2	5.5	GO:0042605	peptide antigen binding(GO:0042605)
0.2	2.9	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.2	82.5	GO:0005525	GTP binding(GO:0005525)
0.2	0.5	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.2	0.5	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.2	1.3	GO:0016778	diphosphotransferase activity(GO:0016778)
0.2	1.2	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.2	1.8	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.2	0.5	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.2	0.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	2.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	2.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	1.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	5.3	GO:0050699	WW domain binding(GO:0050699)
0.1	0.4	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	0.5	GO:0031208	POZ domain binding(GO:0031208)
0.1	3.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	1.6	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	15.1	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	5.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	1.7	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.5	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.1	2.0	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	1.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.4	GO:0004074	biliverdin reductase activity(GO:0004074)
0.1	1.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	4.1	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1	0.3	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.6	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	0.3	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.3	GO:0016160	amylase activity(GO:0016160)
0.1	0.7	GO:0015232	heme transporter activity(GO:0015232)
0.1	1.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.3	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	3.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	0.2	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.1	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1	1.0	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.4	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	1.7	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.6	GO:0098505	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.1	1.2	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.1	2.6	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.1	0.8	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	2.4	GO:0015026	coreceptor activity(GO:0015026)
0.1	1.7	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.3	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	0.6	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	1.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	1.4	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	2.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.8	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	4.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	1.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.6	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	1.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.2	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.0	1.5	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.5	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.5	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.3	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	1.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	25.2	GO:0008270	zinc ion binding(GO:0008270)
0.0	0.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.4	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	3.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	1.1	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.6	GO:0003924	GTPase activity(GO:0003924)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	2.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	3.7	GO:0003823	antigen binding(GO:0003823)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0000182	rDNA binding(GO:0000182)
0.0	0.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	1.7	GO:0003690	double-stranded DNA binding(GO:0003690)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	0.5	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	11.9	GO:0044212	transcription regulatory region DNA binding(GO:0044212)
0.0	0.2	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	1.4	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	1.2	GO:0004871	signal transducer activity(GO:0004871)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.9	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	1.5	GO:0005057	receptor signaling protein activity(GO:0005057)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	7.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	3.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.4	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	2.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	9.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.0	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.9	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.5	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.4	PID TCPTP PATHWAY	Signaling events mediated by TCPTP

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	0.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	1.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	2.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	3.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.5	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.4	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.5	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.2	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0005588	collagen type V trimer(GO:0005588)
0.2	1.1	GO:0001652	granular component(GO:0001652)
0.2	1.0	GO:0033263	CORVET complex(GO:0033263)
0.2	1.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.2	3.6	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.8	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.2	0.5	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2	1.2	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	1.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.7	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.3	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	1.6	GO:0097227	sperm annulus(GO:0097227)
0.1	0.4	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	1.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	2.3	GO:0042599	lamellar body(GO:0042599)
0.1	1.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.7	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.3	GO:0055087	Ski complex(GO:0055087)
0.1	0.3	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.9	GO:0030122	AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.0	0.4	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0044609	DBIRD complex(GO:0044609)
0.0	0.8	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.3	GO:0005827	polar microtubule(GO:0005827)
0.0	0.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	1.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.3	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.6	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.8	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.2	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	2.0	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.8	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.8	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	2.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.3	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	1.1	GO:0016528	sarcoplasm(GO:0016528)
0.0	0.3	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.5	PID ALK1 PATHWAY	ALK1 signaling events
0.2	4.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	3.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	2.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	2.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	11.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	0.8	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	1.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	3.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	3.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	1.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	2.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.0	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.5	ST GAQ PATHWAY	G alpha q Pathway
0.0	2.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	5.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.8	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	1.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	1.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.8	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	1.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	2.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.5	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	1.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.4	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.7	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.7	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0	0.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	2.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.9	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.8	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.9	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.1	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.7	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	0.4	GO:0071253	connexin binding(GO:0071253)
0.0	0.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.6	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.4	GO:0008430	selenium binding(GO:0008430)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.8	GO:0008009	chemokine activity(GO:0008009)
0.0	1.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	7.4	GO:0009996	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.8	5.3	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.7	10.4	GO:0055064	chloride ion homeostasis(GO:0055064)
1.3	3.9	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.2	33.7	GO:0071294	cellular response to zinc ion(GO:0071294)
1.1	4.6	GO:0006542	glutamine biosynthetic process(GO:0006542)
1.1	5.7	GO:0060356	leucine import(GO:0060356)
1.1	3.3	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.0	6.0	GO:0032119	sequestering of zinc ion(GO:0032119)
0.9	0.9	GO:0045168	cell-cell signaling involved in cell fate commitment(GO:0045168)
0.8	6.5	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.7	2.0	GO:0005988	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.6	1.9	GO:0016095	polyprenol catabolic process(GO:0016095)
0.6	3.1	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.6	1.8	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.6	2.3	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.6	2.8	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.5	0.5	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.5	1.6	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
0.5	62.0	GO:0070268	cornification(GO:0070268)
0.5	2.9	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.5	1.5	GO:0007439	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.5	2.3	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.4	1.3	GO:0060279	negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4	0.4	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.4	1.3	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.4	1.7	GO:0035425	autocrine signaling(GO:0035425)
0.4	2.1	GO:1902896	terminal web assembly(GO:1902896)
0.4	0.8	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.4	5.7	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.4	2.8	GO:0070294	renal sodium ion absorption(GO:0070294)
0.4	1.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4	4.4	GO:0009414	response to water deprivation(GO:0009414)
0.4	1.2	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.4	6.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.4	2.3	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.3	2.7	GO:0001661	conditioned taste aversion(GO:0001661)
0.3	1.6	GO:0070295	renal water absorption(GO:0070295)
0.3	1.5	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.3	0.8	GO:0006597	spermine biosynthetic process(GO:0006597)
0.3	2.4	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3	0.3	GO:0060259	positive regulation of behavior(GO:0048520) regulation of feeding behavior(GO:0060259) positive regulation of feeding behavior(GO:2000253)
0.2	3.3	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.2	1.1	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.2	3.0	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.2	0.4	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2	2.6	GO:0070307	lens fiber cell development(GO:0070307)
0.2	4.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	0.5	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2	0.8	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2	0.5	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.2	0.3	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.2	0.6	GO:1903788	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.2	3.2	GO:0003334	keratinocyte development(GO:0003334)
0.2	1.1	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	0.6	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.1	4.1	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.1	0.3	GO:0036466	synaptic vesicle recycling via endosome(GO:0036466)
0.1	0.8	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	4.5	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.1	0.5	GO:0042710	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1	0.7	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1	0.4	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.1	0.5	GO:0070384	Harderian gland development(GO:0070384)
0.1	0.5	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1	4.8	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.7	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.5	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1	1.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.3	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.1	0.3	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1	0.3	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.1	2.2	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.4	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.1	0.6	GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1	0.7	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.1	0.5	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	1.5	GO:0003351	epithelial cilium movement(GO:0003351)
0.1	0.2	GO:0045471	response to ethanol(GO:0045471)
0.1	0.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.5	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1	0.2	GO:1904438	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1	0.5	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.1	0.3	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	2.4	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.1	0.4	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.7	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.2	GO:2000705	dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1	2.1	GO:0060325	face morphogenesis(GO:0060325)
0.1	0.4	GO:0071494	cellular response to UV-C(GO:0071494)
0.1	0.2	GO:0045112	integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.3	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	0.2	GO:0051037	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1	0.5	GO:0090022	myeloid progenitor cell differentiation(GO:0002318) regulation of neutrophil chemotaxis(GO:0090022)
0.1	0.2	GO:0014016	neuroblast differentiation(GO:0014016)
0.1	0.2	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	1.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.7	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	0.5	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	1.6	GO:0007616	long-term memory(GO:0007616)
0.0	0.3	GO:0033133	fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.3	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0	0.3	GO:0051384	response to glucocorticoid(GO:0051384)
0.0	0.7	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.5	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.1	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0	0.4	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.5	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.3	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	1.2	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.1	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.4	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.0	0.2	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.3	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.3	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	1.5	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	5.4	GO:0043542	endothelial cell migration(GO:0043542)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.2	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.2	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.6	GO:0008285	negative regulation of cell proliferation(GO:0008285)
0.0	1.6	GO:0006342	chromatin silencing(GO:0006342)
0.0	0.4	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.7	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.4	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.9	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.3	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.7	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.0	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	4.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	1.7	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	2.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	1.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	2.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.7	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	GO:0005588	collagen type V trimer(GO:0005588)
0.2	3.0	GO:0005687	U4 snRNP(GO:0005687)
0.1	1.2	GO:0005916	fascia adherens(GO:0005916)
0.1	0.5	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1	0.4	GO:0097512	cardiac myofibril(GO:0097512)
0.1	3.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	7.6	GO:0043204	perikaryon(GO:0043204)
0.0	0.8	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.7	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	1.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	2.4	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	11.6	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	1.9	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.1	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	2.9	GO:0016323	basolateral plasma membrane(GO:0016323)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	4.3	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.8	3.1	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.7	35.2	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.6	4.4	GO:0019814	immunoglobulin complex(GO:0019814)
0.6	2.9	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.5	2.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.4	1.2	GO:0031262	Ndc80 complex(GO:0031262)
0.4	7.9	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	1.9	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.3	4.4	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	3.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.3	0.9	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.3	0.9	GO:0031519	PcG protein complex(GO:0031519)
0.3	0.9	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3	0.9	GO:0030689	Noc complex(GO:0030689)
0.3	2.4	GO:0032010	phagolysosome(GO:0032010)
0.3	1.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.3	1.4	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.3	0.8	GO:0036398	TCR signalosome(GO:0036398)
0.2	1.7	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.2	1.2	GO:0098793	presynapse(GO:0098793)
0.2	1.5	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.2	16.8	GO:0015030	Cajal body(GO:0015030)
0.2	2.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.2	1.7	GO:0032584	growth cone membrane(GO:0032584)
0.2	0.9	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	1.4	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2	5.5	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.2	0.9	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.2	1.2	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.2	0.9	GO:0005594	collagen type IX trimer(GO:0005594)
0.2	0.9	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.2	4.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	2.5	GO:0031209	SCAR complex(GO:0031209)
0.2	0.7	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	1.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.2	0.5	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.2	0.7	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	1.1	GO:0043196	varicosity(GO:0043196)
0.2	1.0	GO:0097208	alveolar lamellar body(GO:0097208)
0.2	1.1	GO:0030061	mitochondrial crista(GO:0030061)
0.2	0.8	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.2	1.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2	0.5	GO:0001652	granular component(GO:0001652)
0.2	0.2	GO:0005740	mitochondrial envelope(GO:0005740)
0.1	0.9	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.4	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	1.0	GO:0033269	internode region of axon(GO:0033269)
0.1	2.0	GO:0097227	sperm annulus(GO:0097227)
0.1	0.7	GO:0097125	condensed nuclear chromosome outer kinetochore(GO:0000942) cyclin B1-CDK1 complex(GO:0097125)
0.1	0.9	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	1.2	GO:0032039	integrator complex(GO:0032039)
0.1	0.4	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	0.4	GO:0020005	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1	1.0	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	1.4	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.5	GO:0000811	GINS complex(GO:0000811)
0.1	2.9	GO:0000242	pericentriolar material(GO:0000242)
0.1	1.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	2.0	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	10.7	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	1.4	GO:0043219	lateral loop(GO:0043219)
0.1	0.6	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	0.5	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.8	GO:0044194	cytolytic granule(GO:0044194)
0.1	1.0	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	1.6	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	12.5	GO:0035579	specific granule membrane(GO:0035579)
0.1	1.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.3	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.1	0.5	GO:0032021	NELF complex(GO:0032021)
0.1	0.5	GO:0034457	Mpp10 complex(GO:0034457)
0.1	4.4	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.3	GO:0071159	NF-kappaB complex(GO:0071159)
0.1	0.8	GO:0032389	MutLalpha complex(GO:0032389)
0.1	0.4	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	8.1	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	4.6	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	0.9	GO:0042555	MCM complex(GO:0042555)
0.1	0.6	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.1	4.2	GO:0000139	Golgi membrane(GO:0000139)
0.1	0.3	GO:0060187	cell pole(GO:0060187)
0.1	0.6	GO:1990635	proximal dendrite(GO:1990635)
0.1	0.3	GO:0043034	costamere(GO:0043034)
0.1	1.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	1.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	0.8	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.5	GO:0071817	MMXD complex(GO:0071817)
0.1	0.5	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.5	GO:0061689	tricellular tight junction(GO:0061689)
0.1	0.6	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.2	GO:0032302	MutSbeta complex(GO:0032302)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.3	GO:0030314	junctional membrane complex(GO:0030314)
0.1	0.3	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.3	GO:0070552	BRISC complex(GO:0070552)
0.1	1.3	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.5	GO:0031224	intrinsic component of membrane(GO:0031224)
0.1	2.5	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	0.7	GO:0045180	basal cortex(GO:0045180)
0.1	0.6	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	1.0	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	1.2	GO:0032059	bleb(GO:0032059)
0.1	0.6	GO:0000125	PCAF complex(GO:0000125)
0.1	0.3	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	0.1	GO:0035838	growing cell tip(GO:0035838)
0.1	2.7	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	0.4	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.8	GO:0045120	pronucleus(GO:0045120)
0.1	0.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	0.6	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	0.7	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.4	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.9	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	1.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.4	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	2.3	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	0.4	GO:0008537	proteasome activator complex(GO:0008537)
0.1	0.4	GO:0031045	dense core granule(GO:0031045)
0.1	0.5	GO:0070652	HAUS complex(GO:0070652)
0.1	0.1	GO:0042382	paraspeckles(GO:0042382)
0.1	0.1	GO:0042025	host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1	1.8	GO:0042629	mast cell granule(GO:0042629)
0.1	1.8	GO:0051233	spindle midzone(GO:0051233)
0.1	2.1	GO:1904115	axon cytoplasm(GO:1904115)
0.1	1.2	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.6	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	1.7	GO:0001726	ruffle(GO:0001726)
0.1	1.4	GO:0000178	exosome (RNase complex)(GO:0000178)
0.1	0.2	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.1	0.1	GO:0030137	COPI-coated vesicle(GO:0030137)
0.1	0.4	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1	1.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.4	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	2.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.2	GO:0070195	growth hormone receptor complex(GO:0070195)
0.1	1.0	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	2.1	GO:0031672	A band(GO:0031672)
0.1	0.8	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.8	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.9	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	3.5	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	1.0	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	3.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.7	GO:0000145	exocyst(GO:0000145)
0.0	0.3	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.5	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	1.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.0	0.9	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.3	GO:0005787	signal peptidase complex(GO:0005787)
0.0	2.5	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.0	0.6	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.7	GO:0005840	ribosome(GO:0005840)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	2.3	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	1.0	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.3	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.5	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.4	GO:0016013	syntrophin complex(GO:0016013)
0.0	2.4	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.8	GO:1990391	DNA repair complex(GO:1990391)
0.0	2.6	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	1.4	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	0.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.3	GO:0097452	GAIT complex(GO:0097452)
0.0	0.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	1.8	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	0.1	GO:0016459	myosin complex(GO:0016459)
0.0	1.2	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.4	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	3.5	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	2.2	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.5	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.9	GO:0030684	preribosome(GO:0030684)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.6	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	13.1	GO:0016607	nuclear speck(GO:0016607)
0.0	0.7	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	8.1	GO:0031965	nuclear membrane(GO:0031965)
0.0	1.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	1.1	GO:0005811	lipid particle(GO:0005811)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.6	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.3	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	1.0	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0030905	retromer, tubulation complex(GO:0030905)
0.0	0.2	GO:0044292	dendrite terminus(GO:0044292) dendritic growth cone(GO:0044294)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.0	1.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.7	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0	1.9	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0005960	glycine cleavage complex(GO:0005960)
0.0	0.7	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.6	GO:0071564	npBAF complex(GO:0071564) nBAF complex(GO:0071565)
0.0	0.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.7	GO:0044455	mitochondrial membrane part(GO:0044455)
0.0	1.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	1.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.1	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.3	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.2	GO:0032982	myosin filament(GO:0032982)
0.0	0.0	GO:0097449	astrocyte projection(GO:0097449)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.9	GO:0005814	centriole(GO:0005814)
0.0	0.1	GO:0001533	cornified envelope(GO:0001533)
0.0	0.7	GO:0043204	perikaryon(GO:0043204)
0.0	0.5	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.2	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.1	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
0.0	5.8	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.0	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.0	1.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	1.1	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	1.1	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.5	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	47.3	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	1.9	GO:0005743	mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0	0.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	1.4	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.0	GO:0098858	actin-based cell projection(GO:0098858)
0.0	0.2	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.0	GO:0002177	manchette(GO:0002177)
0.0	1.5	GO:0019867	outer membrane(GO:0019867)
0.0	0.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	1.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.5	PID ILK PATHWAY	Integrin-linked kinase signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.4	5.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	6.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.3	8.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	1.7	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	4.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	3.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	8.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	3.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	2.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	3.3	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	10.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.6	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	2.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	6.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	0.3	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.1	1.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	0.8	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	4.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	2.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	4.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	1.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	0.9	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.7	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	4.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	1.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	0.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.1	1.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	0.7	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	3.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	2.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	3.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME DEFENSINS	Genes involved in Defensins
0.0	0.8	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	1.6	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.4	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.4	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	2.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.4	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	2.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	3.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.1	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	7.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	1.0	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	1.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	13.9	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.8	3.8	GO:0016403	dimethylargininase activity(GO:0016403)
0.7	3.0	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.5	1.8	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.4	3.0	GO:0071253	connexin binding(GO:0071253)
0.3	7.8	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.3	0.9	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.3	6.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	0.8	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3	2.9	GO:0031013	troponin I binding(GO:0031013)
0.2	2.3	GO:0051425	PTB domain binding(GO:0051425)
0.2	1.6	GO:0070492	oligosaccharide binding(GO:0070492)
0.2	0.9	GO:0008431	vitamin E binding(GO:0008431)
0.2	1.3	GO:0003998	acylphosphatase activity(GO:0003998)
0.2	0.5	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.2	0.6	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	14.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	1.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	3.7	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.4	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	3.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	1.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.6	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	0.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.5	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1	0.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.3	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	2.0	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	0.3	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	2.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	1.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	2.0	GO:0001968	fibronectin binding(GO:0001968)
0.1	8.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.7	GO:0043426	MRF binding(GO:0043426)
0.1	0.6	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	8.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	0.3	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.3	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.4	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.4	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.2	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.5	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	1.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.7	GO:0005112	Notch binding(GO:0005112)
0.0	1.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	1.0	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.7	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.4	GO:0031014	troponin T binding(GO:0031014)
0.0	0.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	4.6	GO:0005178	integrin binding(GO:0005178)
0.0	1.0	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.9	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.1	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	0.1	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.5	GO:0000217	DNA secondary structure binding(GO:0000217)
0.0	0.9	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.6	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	1.5	GO:0002039	p53 binding(GO:0002039)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	2.2	GO:0044325	ion channel binding(GO:0044325)
0.0	0.2	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.1	GO:0070739	NEDD8 transferase activity(GO:0019788) protein-glutamic acid ligase activity(GO:0070739)
0.0	0.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	1.3	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	1.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.9	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	2.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	2.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	2.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	3.1	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	1.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	2.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.3	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.5	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	1.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.5	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.8	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.4	ST GAQ PATHWAY	G alpha q Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	2.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.9	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	2.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	1.1	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.7	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.5	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.6	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.4	1.3	GO:0019959	interleukin-8 binding(GO:0019959)
0.4	1.2	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.4	1.6	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4	1.2	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3	0.9	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.3	1.4	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3	1.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2	1.5	GO:0004522	ribonuclease A activity(GO:0004522)
0.2	2.4	GO:0042731	PH domain binding(GO:0042731)
0.2	1.7	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2	1.9	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	2.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	1.6	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.2	1.5	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2	1.8	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.2	0.7	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2	0.5	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1	0.4	GO:0015616	DNA translocase activity(GO:0015616)
0.1	3.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.6	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.5	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1	0.4	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	3.9	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	1.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	1.1	GO:0000150	recombinase activity(GO:0000150)
0.1	3.0	GO:0070064	proline-rich region binding(GO:0070064)
0.1	2.0	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	2.0	GO:0017081	chloride channel regulator activity(GO:0017081)
0.1	1.0	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	2.1	GO:0005521	lamin binding(GO:0005521)
0.1	1.9	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1	1.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.4	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1	5.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.1	5.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.3	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.1	2.6	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.2	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.7	GO:0045499	chemorepellent activity(GO:0045499)
0.0	1.5	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0047708	biotinidase activity(GO:0047708)
0.0	1.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.2	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.0	1.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.4	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	5.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.8	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.0	0.5	GO:0005537	mannose binding(GO:0005537)
0.0	1.8	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	5.7	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.7	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	3.9	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	1.7	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.1	GO:0019863	immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.0	0.6	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.5	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	1.6	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.3	2.2	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	0.9	GO:0098626	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2	0.9	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.2	0.9	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.2	1.2	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2	1.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.2	0.9	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2	0.9	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	0.6	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.2	0.6	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2	0.8	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.2	0.6	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.2	1.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.6	GO:0047718	androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1	0.7	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	0.4	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1	3.7	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.2	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1	0.9	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.3	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.1	1.8	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.3	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.3	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1	0.3	GO:0032089	NACHT domain binding(GO:0032089)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.6	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.8	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	1.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	1.5	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.4	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.3	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1	0.5	GO:0043237	laminin-1 binding(GO:0043237)
0.1	1.7	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.5	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.2	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.1	2.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.2	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1	0.2	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.1	0.4	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.7	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.5	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	1.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.5	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.2	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.1	0.7	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.3	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.1	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.3	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.3	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.4	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.1	GO:0031716	calcitonin receptor binding(GO:0031716)
0.0	0.4	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0	1.9	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.2	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	1.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0	0.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.0	0.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.7	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.5	GO:0043295	glutathione binding(GO:0043295)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.5	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.3	GO:0034711	inhibin binding(GO:0034711)
0.0	0.7	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.2	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.4	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.2	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.2	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0004769	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0015616	DNA translocase activity(GO:0015616)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.3	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.7	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0050294	steroid sulfotransferase activity(GO:0050294)
0.0	1.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.4	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.7	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	1.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.7	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0008940	nitrate reductase activity(GO:0008940)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.4	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0	0.5	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	2.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0043532	angiostatin binding(GO:0043532)
0.0	0.1	GO:0099609	microtubule lateral binding(GO:0099609)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004797	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.3	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0047820	D-glutamate cyclase activity(GO:0047820)
0.0	0.1	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.1	GO:0004962	endothelin receptor activity(GO:0004962)
0.0	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.0	0.2	GO:0035240	dopamine binding(GO:0035240)
0.0	0.2	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0018636	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.3	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.7	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	1.2	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	0.2	GO:0001163	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.0	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.0	0.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.3	GO:0001848	complement binding(GO:0001848)
0.0	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.0	0.3	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.4	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.0	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.0	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	1.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.9	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.0	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.0	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0	0.0	GO:0004817	cysteine-tRNA ligase activity(GO:0004817)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	35.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.6	12.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.6	7.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	7.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.3	5.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	2.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	5.5	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.3	12.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2	9.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	16.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	2.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	1.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	8.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	8.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.7	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	3.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	1.6	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	13.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	0.7	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.9	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	2.1	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1	1.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	2.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	1.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	4.4	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	1.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	3.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	1.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	1.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.1	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	2.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.5	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	1.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	1.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	1.1	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	2.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	3.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	5.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	1.0	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.9	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	1.0	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	1.7	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.8	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.9	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	1.2	GO:0045179	apical cortex(GO:0045179)
0.1	0.6	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1	0.7	GO:0097422	tubular endosome(GO:0097422)
0.1	0.8	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.1	1.0	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.6	GO:0036398	TCR signalosome(GO:0036398)
0.1	1.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0043235	receptor complex(GO:0043235)
0.1	0.2	GO:0071546	pi-body(GO:0071546)
0.1	0.7	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.8	GO:0035976	AP1 complex(GO:0035976)
0.1	8.8	GO:0043195	terminal bouton(GO:0043195)
0.1	0.5	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.2	GO:0005960	glycine cleavage complex(GO:0005960)
0.1	0.7	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.3	GO:0070985	TFIIK complex(GO:0070985)
0.1	1.9	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	0.4	GO:0008537	proteasome activator complex(GO:0008537)
0.1	0.6	GO:0033391	chromatoid body(GO:0033391)
0.1	1.1	GO:0042599	lamellar body(GO:0042599)
0.1	0.4	GO:0097452	GAIT complex(GO:0097452)
0.0	1.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	1.5	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.3	GO:0070852	cell body fiber(GO:0070852)
0.0	0.8	GO:0005922	connexon complex(GO:0005922)
0.0	0.2	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.4	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.7	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.8	GO:0005811	lipid particle(GO:0005811)
0.0	0.9	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.2	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	0.9	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0031673	H zone(GO:0031673)
0.0	0.7	GO:0032156	septin cytoskeleton(GO:0032156)
0.0	3.1	GO:0005604	basement membrane(GO:0005604)
0.0	1.0	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.3	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.6	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0090543	Flemming body(GO:0090543)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	2.0	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.9	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	3.6	GO:0005770	late endosome(GO:0005770)
0.0	1.5	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.3	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.3	GO:0031082	BLOC complex(GO:0031082)
0.0	2.3	GO:0001726	ruffle(GO:0001726)
0.0	0.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.4	GO:0030175	filopodium(GO:0030175)
0.0	0.6	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	1.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.6	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	1.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.4	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.3	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.9	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	8.3	GO:1904899	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.8	4.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.7	2.2	GO:1902303	negative regulation of potassium ion export(GO:1902303)
0.7	2.0	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.7	3.3	GO:0003408	optic cup formation involved in camera-type eye development(GO:0003408)
0.6	1.9	GO:0051300	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.6	1.8	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.5	2.7	GO:1990834	response to odorant(GO:1990834)
0.5	1.4	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.5	1.8	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.4	1.8	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.4	1.8	GO:0006272	leading strand elongation(GO:0006272)
0.4	1.7	GO:0002270	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.4	2.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.4	2.1	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.4	2.1	GO:0015961	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4	2.0	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.4	3.7	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4	4.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.4	1.8	GO:0021553	olfactory nerve development(GO:0021553)
0.4	1.1	GO:0019858	cytosine metabolic process(GO:0019858)
0.3	1.7	GO:0006543	glutamine catabolic process(GO:0006543)
0.3	2.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.3	1.4	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.3	4.1	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.3	1.0	GO:1901355	response to rapamycin(GO:1901355)
0.3	1.3	GO:0097476	spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3	1.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.3	1.3	GO:0042418	epinephrine biosynthetic process(GO:0042418)
0.3	1.2	GO:0090402	oncogene-induced cell senescence(GO:0090402)
0.3	1.5	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.3	1.5	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.3	0.9	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3	1.1	GO:1903438	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3	1.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.3	0.8	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.3	2.7	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.3	0.8	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.3	1.9	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.3	1.6	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
0.3	1.6	GO:0051013	microtubule severing(GO:0051013)
0.3	0.8	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2	1.0	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.2	0.2	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2	2.4	GO:0001866	NK T cell proliferation(GO:0001866)
0.2	0.7	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2	0.7	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.2	1.9	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.2	0.9	GO:0060717	chorion development(GO:0060717)
0.2	0.7	GO:0019230	proprioception(GO:0019230)
0.2	0.7	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2	1.1	GO:0019348	dolichol metabolic process(GO:0019348)
0.2	1.6	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.2	0.2	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.2	0.4	GO:2001038	regulation of cellular response to drug(GO:2001038)
0.2	8.9	GO:0006270	DNA replication initiation(GO:0006270)
0.2	0.7	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.2	0.7	GO:0030901	midbrain development(GO:0030901)
0.2	1.5	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.2	0.7	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.2	0.6	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2	1.3	GO:0043418	homocysteine catabolic process(GO:0043418)
0.2	0.9	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.2	2.3	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2	0.2	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2	1.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.2	0.2	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2	0.4	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2	0.6	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2	2.9	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.2	0.8	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.2	0.6	GO:0006172	ADP biosynthetic process(GO:0006172)
0.2	0.6	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.2	0.8	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.2	0.6	GO:0061074	regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.2	0.7	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2	0.6	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.2	0.5	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.2	0.5	GO:0043105	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2	0.5	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.2	0.7	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.2	0.5	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2	0.3	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.2	1.9	GO:0030322	stabilization of membrane potential(GO:0030322)
0.2	3.0	GO:0006337	nucleosome disassembly(GO:0006337)
0.2	1.0	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.2	1.8	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	0.5	GO:0045659	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2	0.7	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	0.6	GO:0071895	odontoblast differentiation(GO:0071895)
0.2	2.7	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.2	1.0	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.2	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.5	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.2	0.5	GO:0051684	maintenance of Golgi location(GO:0051684)
0.2	0.9	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2	0.2	GO:0070585	protein localization to mitochondrion(GO:0070585)
0.1	1.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.4	GO:1904800	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.1	1.6	GO:0031507	heterochromatin assembly(GO:0031507)
0.1	1.5	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.1	0.6	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.1	0.6	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1	0.3	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
0.1	0.7	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.1	2.5	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	1.0	GO:1901314	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	0.4	GO:0052031	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1	0.4	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	1.2	GO:0017038	protein import(GO:0017038)
0.1	0.4	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	0.7	GO:0006740	NADPH regeneration(GO:0006740)
0.1	0.4	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.1	0.7	GO:0070370	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1	3.4	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.1	0.4	GO:0030307	positive regulation of cell growth(GO:0030307)
0.1	0.1	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1	0.4	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	1.2	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	0.9	GO:2001300	lipoxin metabolic process(GO:2001300)
0.1	1.4	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.9	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.4	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1	1.4	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.1	0.6	GO:0015862	uridine transport(GO:0015862)
0.1	5.5	GO:0043486	histone exchange(GO:0043486)
0.1	0.4	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.4	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	1.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1	0.5	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1	0.7	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.2	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
0.1	0.2	GO:0098727	maintenance of cell number(GO:0098727)
0.1	2.6	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	1.5	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.1	0.4	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1	0.6	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.7	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.5	GO:0044467	glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.1	2.4	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.2	GO:0043633	polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.1	0.3	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	0.6	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.4	GO:0050957	equilibrioception(GO:0050957)
0.1	0.4	GO:1901858	regulation of mitochondrial DNA replication(GO:0090296) regulation of mitochondrial DNA metabolic process(GO:1901858)
0.1	0.4	GO:0060947	cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.1	0.2	GO:0042026	protein refolding(GO:0042026)
0.1	0.4	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.8	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.1	0.2	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	0.2	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1	0.8	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.8	GO:1904690	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1	0.4	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	0.3	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	1.5	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	0.2	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	0.3	GO:0099552	trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1	0.2	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.1	0.1	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1	0.5	GO:0009233	menaquinone metabolic process(GO:0009233)
0.1	0.7	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	0.2	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.4	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1	0.3	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1	0.2	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1	0.2	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.8	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.1	1.5	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.1	0.5	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.1	0.1	GO:0060031	mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1	0.7	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.5	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.5	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.1	0.8	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	1.7	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1	1.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.2	GO:0021846	cell proliferation in forebrain(GO:0021846) forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.6	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.1	0.6	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1	0.2	GO:2000303	positive regulation of lipid biosynthetic process(GO:0046889) regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1	0.3	GO:1904744	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
0.1	0.5	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.3	GO:0035283	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.8	GO:0061469	response to corticotropin-releasing hormone(GO:0043435) regulation of type B pancreatic cell proliferation(GO:0061469) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1	0.2	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1	0.2	GO:1902576	negative regulation of nuclear cell cycle DNA replication(GO:1902576)
0.1	0.4	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.4	GO:0021997	neural plate axis specification(GO:0021997)
0.1	0.5	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.4	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.3	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	0.6	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	0.3	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	0.3	GO:2000973	regulation of pro-B cell differentiation(GO:2000973)
0.1	1.1	GO:0006265	DNA topological change(GO:0006265)
0.1	0.4	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.7	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.1	0.2	GO:0033504	floor plate development(GO:0033504)
0.1	0.2	GO:1900060	glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1	0.4	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
0.1	0.7	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.8	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.4	GO:0001315	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1	0.3	GO:2001295	malonyl-CoA biosynthetic process(GO:2001295)
0.1	0.2	GO:0042360	vitamin E metabolic process(GO:0042360)
0.1	0.2	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1	0.2	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.1	1.9	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	0.2	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.2	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.1	0.3	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1	0.2	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.1	5.3	GO:0006334	nucleosome assembly(GO:0006334)
0.1	0.4	GO:0090625	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	0.4	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.1	0.2	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.1	0.4	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.4	GO:0072642	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1	0.7	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.8	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.4	GO:0071105	response to interleukin-11(GO:0071105)
0.1	0.4	GO:0021759	globus pallidus development(GO:0021759)
0.1	0.4	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.1	0.2	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.1	0.9	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.1	1.4	GO:0016180	snRNA processing(GO:0016180)
0.1	0.3	GO:0031291	Ran protein signal transduction(GO:0031291)
0.1	0.2	GO:0007518	myoblast fate determination(GO:0007518)
0.1	0.3	GO:0021896	forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1	0.1	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.2	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.7	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.1	0.3	GO:0045218	zonula adherens maintenance(GO:0045218)
0.1	0.2	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.5	GO:0010993	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304)
0.1	1.0	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.3	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1	0.7	GO:0006188	IMP biosynthetic process(GO:0006188) IMP salvage(GO:0032264)
0.1	0.2	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.1	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	0.2	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	1.9	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	0.3	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1	0.2	GO:0061113	signal transduction downstream of smoothened(GO:0007227) ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) pancreas morphogenesis(GO:0061113)
0.1	1.5	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.1	0.5	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.1	0.8	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.6	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.1	0.2	GO:2000374	regulation of oxygen metabolic process(GO:2000374)
0.1	3.7	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.1	0.1	GO:2000291	myoblast proliferation(GO:0051450) regulation of myoblast proliferation(GO:2000291)
0.1	0.1	GO:1902822	regulation of late endosome to lysosome transport(GO:1902822)
0.1	0.4	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1	0.4	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.1	0.2	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.3	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.1	0.8	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.1	0.7	GO:0032310	prostaglandin secretion(GO:0032310)
0.1	0.2	GO:0015808	L-alanine transport(GO:0015808)
0.1	0.9	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.2	GO:0009258	10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1	0.4	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	0.2	GO:0010586	miRNA metabolic process(GO:0010586)
0.1	0.3	GO:0030070	insulin processing(GO:0030070)
0.1	0.5	GO:0015074	DNA integration(GO:0015074)
0.1	1.0	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	2.2	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.1	0.3	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.8	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.2	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1	0.5	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.2	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	0.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.3	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.1	0.8	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.2	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1	0.3	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	0.2	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.2	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.1	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.3	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1	0.3	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.1	0.1	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1	0.3	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.1	0.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	0.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	1.9	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.1	0.1	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1	0.4	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	0.8	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1	0.8	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.1	GO:2001293	malonyl-CoA metabolic process(GO:2001293)
0.0	0.2	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.4	GO:0010225	response to UV-C(GO:0010225)
0.0	0.1	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0	0.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.2	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.7	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	1.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.3	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0	0.4	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.4	GO:0001711	endodermal cell fate commitment(GO:0001711)
0.0	3.7	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.5	GO:0016246	RNA interference(GO:0016246)
0.0	0.3	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.3	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.2	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.7	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.0	0.7	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.3	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0072014	proximal tubule development(GO:0072014)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.4	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.1	GO:0042823	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.0	0.3	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.7	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.4	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0	0.3	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0	0.3	GO:0019079	viral genome replication(GO:0019079)
0.0	0.4	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0	0.0	GO:0003358	noradrenergic neuron development(GO:0003358)
0.0	0.4	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.3	GO:0044380	protein localization to cytoskeleton(GO:0044380)
0.0	0.5	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.1	GO:0050885	neuromuscular process controlling balance(GO:0050885)
0.0	0.0	GO:0099545	trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0	0.0	GO:0031133	regulation of axon diameter(GO:0031133)
0.0	0.3	GO:0007549	dosage compensation(GO:0007549)
0.0	0.5	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	1.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.8	GO:0097369	sodium ion import(GO:0097369)
0.0	0.3	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.5	GO:0075713	establishment of integrated proviral latency(GO:0075713)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.2	GO:0051321	meiotic cell cycle(GO:0051321)
0.0	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.0	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.0	1.3	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0038030	non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0	0.4	GO:0007051	spindle organization(GO:0007051)
0.0	0.2	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.2	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.3	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.7	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.2	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.1	GO:0050893	sensory processing(GO:0050893)
0.0	0.3	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.8	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.3	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.3	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.3	GO:0006882	cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.0	0.8	GO:0010470	regulation of gastrulation(GO:0010470)
0.0	0.3	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.2	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405)
0.0	0.1	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
0.0	0.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.3	GO:0021794	thalamus development(GO:0021794)
0.0	0.2	GO:0042631	cellular response to water deprivation(GO:0042631)
0.0	0.2	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.0	0.2	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.3	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0071492	response to mycotoxin(GO:0010046) cellular response to UV-A(GO:0071492)
0.0	0.4	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.4	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.0	0.1	GO:2000114	regulation of establishment or maintenance of cell polarity(GO:0032878) regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	1.7	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.0	0.2	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.5	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.1	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.1	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.3	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.8	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0032868	response to insulin(GO:0032868)
0.0	0.6	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.3	GO:0014029	neural crest formation(GO:0014029)
0.0	0.3	GO:0010259	multicellular organism aging(GO:0010259)
0.0	0.1	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.0	0.6	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.0	0.4	GO:0006970	response to osmotic stress(GO:0006970)
0.0	0.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.4	GO:0016579	protein deubiquitination(GO:0016579) protein modification by small protein removal(GO:0070646)
0.0	0.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	0.5	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.1	GO:1902669	positive regulation of axon guidance(GO:1902669)
0.0	0.4	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.0	0.3	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.5	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0002188	formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0	2.1	GO:0007286	spermatid development(GO:0007286)
0.0	0.5	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	1.0	GO:0031640	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0	0.2	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.0	GO:0048515	spermatid differentiation(GO:0048515)
0.0	0.2	GO:0051168	nuclear export(GO:0051168)
0.0	0.0	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
0.0	1.4	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0	1.1	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.3	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:1901993	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	1.7	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.3	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.3	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.2	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.3	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.2	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)
0.0	0.4	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0055072	iron ion homeostasis(GO:0055072)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.2	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	0.4	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.5	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0070781	response to biotin(GO:0070781)
0.0	0.2	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.2	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.4	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.3	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.1	GO:0008344	adult locomotory behavior(GO:0008344)
0.0	0.6	GO:0006839	mitochondrial transport(GO:0006839)
0.0	0.2	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.1	GO:0009409	response to cold(GO:0009409)
0.0	0.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.0	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.9	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.9	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.9	GO:0009301	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0010663	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.3	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.9	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.0	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.2	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.0	GO:0009994	oocyte differentiation(GO:0009994)
0.0	0.3	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.2	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.0	0.5	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.2	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.0	0.2	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	0.2	GO:0019054	modulation by virus of host process(GO:0019054)
0.0	0.1	GO:0015870	acetylcholine transport(GO:0015870)
0.0	0.3	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0	0.0	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.0	0.3	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.0	GO:0072537	fibroblast activation(GO:0072537)
0.0	0.1	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0	0.1	GO:0070528	protein kinase C signaling(GO:0070528)
0.0	0.2	GO:1904814	regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0	0.1	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.1	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0	0.0	GO:0001777	T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.1	GO:0036269	swimming behavior(GO:0036269)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.1	GO:0061303	cornea development in camera-type eye(GO:0061303)
0.0	0.3	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.1	GO:0001556	oocyte maturation(GO:0001556)
0.0	0.1	GO:0006116	NADH oxidation(GO:0006116)
0.0	0.2	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.2	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.2	GO:0072348	sulfur compound transport(GO:0072348)
0.0	0.4	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.0	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0	0.2	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.1	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.5	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.2	GO:0001510	RNA methylation(GO:0001510)
0.0	0.2	GO:0033622	integrin activation(GO:0033622)
0.0	0.2	GO:0044786	cell cycle DNA replication(GO:0044786)
0.0	0.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.0	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.2	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.0	GO:2000366	regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0	0.1	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.0	GO:1903028	positive regulation of opsonization(GO:1903028)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.0	GO:0043174	nucleoside salvage(GO:0043174)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:1902961	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) gap junction assembly(GO:0016264)
0.0	0.2	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.2	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.2	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.1	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0036342	post-anal tail morphogenesis(GO:0036342)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	2.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	7.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	3.6	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.5	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.3	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.9	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	0.7	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	0.9	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	0.7	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	1.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.0	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0	3.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	3.2	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.9	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.8	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	1.9	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.1	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	1.2	REACTOME NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Neurotransmitter Release Cycle
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.8	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	1.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	1.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.6	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.8	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.4	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	0.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	1.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.3	37.1	GO:0097209	epidermal lamellar body(GO:0097209)
3.8	30.4	GO:0005610	laminin-5 complex(GO:0005610)
2.6	17.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
2.1	26.8	GO:0097470	ribbon synapse(GO:0097470)
1.9	15.0	GO:0098845	postsynaptic endosome(GO:0098845)
1.8	5.4	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
1.8	5.4	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
1.6	4.9	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
1.6	4.9	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
1.6	17.7	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
1.6	36.6	GO:0030056	hemidesmosome(GO:0030056)
1.5	20.5	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.4	7.2	GO:0031905	early endosome lumen(GO:0031905)
1.4	8.6	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
1.4	4.2	GO:0044393	microspike(GO:0044393)
1.2	3.7	GO:0072534	perineuronal net(GO:0072534)
1.2	13.4	GO:0097443	sorting endosome(GO:0097443)
1.1	8.0	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
1.1	5.6	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
1.0	15.6	GO:0090543	Flemming body(GO:0090543)
1.0	1.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
1.0	22.3	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
1.0	4.9	GO:0045323	interleukin-1 receptor complex(GO:0045323)
1.0	4.8	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
1.0	29.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.9	6.4	GO:0032593	insulin-responsive compartment(GO:0032593)
0.9	9.0	GO:0042584	chromaffin granule membrane(GO:0042584)
0.9	2.6	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.9	8.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.9	17.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.9	8.5	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.8	2.5	GO:0070435	Shc-EGFR complex(GO:0070435)
0.8	3.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.8	4.0	GO:0071438	invadopodium membrane(GO:0071438)
0.8	13.4	GO:0005922	connexon complex(GO:0005922)
0.8	14.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.8	6.1	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.8	6.0	GO:0005587	collagen type IV trimer(GO:0005587)
0.8	0.8	GO:1990246	uniplex complex(GO:1990246)
0.7	4.4	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.7	2.2	GO:0036128	CatSper complex(GO:0036128)
0.7	5.0	GO:0031415	NatA complex(GO:0031415)
0.7	5.0	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.7	1.4	GO:0097342	ripoptosome(GO:0097342)
0.7	2.8	GO:1990075	periciliary membrane compartment(GO:1990075)
0.7	2.1	GO:0043235	receptor complex(GO:0043235)
0.7	2.7	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.7	18.1	GO:0097228	sperm principal piece(GO:0097228)
0.7	2.0	GO:0045180	basal cortex(GO:0045180)
0.7	5.3	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.7	3.3	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.6	28.5	GO:0045095	keratin filament(GO:0045095)
0.6	3.2	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.6	3.2	GO:0071986	Ragulator complex(GO:0071986)
0.6	5.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.6	1.9	GO:0005826	actomyosin contractile ring(GO:0005826)
0.6	1.3	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.6	2.5	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.6	3.7	GO:0051286	cell tip(GO:0051286)
0.6	9.8	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.6	4.3	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.6	2.9	GO:0097149	centralspindlin complex(GO:0097149)
0.6	1.7	GO:0070557	PCNA-p21 complex(GO:0070557)
0.6	5.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.6	28.8	GO:0001533	cornified envelope(GO:0001533)
0.6	0.6	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.6	1.7	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.6	1.1	GO:0098576	lumenal side of membrane(GO:0098576)
0.6	2.3	GO:0060171	myosin I complex(GO:0045160) stereocilium membrane(GO:0060171)
0.5	2.7	GO:0032449	CBM complex(GO:0032449)
0.5	4.9	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5	1.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.5	2.1	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.5	7.4	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5	14.3	GO:0031143	pseudopodium(GO:0031143)
0.5	2.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.5	2.1	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.5	2.6	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.5	3.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.5	1.5	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.5	1.0	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.5	1.5	GO:0030017	sarcomere(GO:0030017)
0.5	4.9	GO:0042612	MHC class I protein complex(GO:0042612)
0.5	4.3	GO:0030057	desmosome(GO:0030057)
0.5	2.8	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.5	3.3	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.5	1.9	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.5	1.4	GO:0002081	outer acrosomal membrane(GO:0002081)
0.4	2.6	GO:0090661	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.4	1.3	GO:0043159	acrosomal matrix(GO:0043159)
0.4	1.3	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.4	2.6	GO:0032010	phagolysosome(GO:0032010)
0.4	9.0	GO:0002080	acrosomal membrane(GO:0002080)
0.4	0.9	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.4	1.7	GO:0036449	microtubule minus-end(GO:0036449)
0.4	5.3	GO:0097433	dense body(GO:0097433)
0.4	0.4	GO:0071203	WASH complex(GO:0071203)
0.4	2.4	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.4	2.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.4	3.6	GO:0005955	calcineurin complex(GO:0005955)
0.4	1.2	GO:0016938	kinesin I complex(GO:0016938)
0.4	3.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.4	1.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4	1.2	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4	1.9	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.4	2.3	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4	1.2	GO:0044609	DBIRD complex(GO:0044609)
0.4	1.9	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.4	10.0	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4	1.5	GO:0055087	Ski complex(GO:0055087)
0.4	4.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.4	38.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.4	1.1	GO:0018444	translation release factor complex(GO:0018444)
0.4	1.5	GO:0070822	Sin3-type complex(GO:0070822)
0.4	20.9	GO:0005882	intermediate filament(GO:0005882)
0.4	0.4	GO:1902555	endoribonuclease complex(GO:1902555)
0.4	0.4	GO:1990909	Wnt signalosome(GO:1990909)
0.4	1.9	GO:0099568	cytoplasmic region(GO:0099568)
0.4	13.5	GO:0043034	costamere(GO:0043034)
0.4	3.3	GO:0097413	Lewy body(GO:0097413)
0.4	4.4	GO:0000815	ESCRT III complex(GO:0000815)
0.4	1.5	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.4	1.1	GO:0035869	ciliary transition zone(GO:0035869)
0.4	3.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.4	1.1	GO:0001940	male pronucleus(GO:0001940)
0.4	2.5	GO:0072487	MSL complex(GO:0072487)
0.4	5.3	GO:0005869	dynactin complex(GO:0005869)
0.4	0.4	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.4	0.4	GO:0097422	tubular endosome(GO:0097422)
0.4	2.8	GO:0033391	chromatoid body(GO:0033391)
0.4	1.1	GO:0044423	virion(GO:0019012) virion part(GO:0044423)
0.4	2.5	GO:0031941	filamentous actin(GO:0031941)
0.3	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.3	3.5	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3	1.4	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.3	1.7	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.3	1.4	GO:0070985	TFIIK complex(GO:0070985)
0.3	1.0	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3	6.4	GO:0035578	azurophil granule lumen(GO:0035578)
0.3	2.7	GO:0008290	F-actin capping protein complex(GO:0008290)
0.3	1.7	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3	0.3	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3	1.0	GO:0097441	basilar dendrite(GO:0097441)
0.3	2.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.3	3.0	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3	1.6	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.3	1.3	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.3	1.0	GO:0071020	post-spliceosomal complex(GO:0071020)
0.3	1.0	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.3	0.6	GO:0001739	sex chromatin(GO:0001739)
0.3	9.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.3	4.5	GO:0036020	endolysosome membrane(GO:0036020)
0.3	10.4	GO:0070069	cytochrome complex(GO:0070069)
0.3	0.6	GO:0001939	female pronucleus(GO:0001939)
0.3	1.6	GO:0042643	actomyosin, actin portion(GO:0042643)
0.3	1.2	GO:0042587	glycogen granule(GO:0042587)
0.3	24.6	GO:0034707	chloride channel complex(GO:0034707)
0.3	2.5	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	0.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3	0.3	GO:0033553	rDNA heterochromatin(GO:0033553)
0.3	12.9	GO:0001772	immunological synapse(GO:0001772)
0.3	1.2	GO:0044611	nuclear pore inner ring(GO:0044611)
0.3	1.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3	5.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.3	2.1	GO:0031526	brush border membrane(GO:0031526)
0.3	2.0	GO:0061617	MICOS complex(GO:0061617)
0.3	0.9	GO:0071751	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.3	6.3	GO:0005838	proteasome regulatory particle(GO:0005838)
0.3	1.7	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.3	2.9	GO:0005641	nuclear envelope lumen(GO:0005641)
0.3	2.8	GO:0097255	R2TP complex(GO:0097255)
0.3	1.7	GO:0097449	astrocyte projection(GO:0097449)
0.3	1.1	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3	10.7	GO:0002102	podosome(GO:0002102)
0.3	0.8	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.3	1.4	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.3	7.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.3	1.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3	0.5	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.3	2.1	GO:0031931	TORC1 complex(GO:0031931)
0.3	2.9	GO:0070765	gamma-secretase complex(GO:0070765)
0.3	1.6	GO:0005688	U6 snRNP(GO:0005688)
0.3	0.3	GO:0035976	AP1 complex(GO:0035976)
0.3	1.3	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3	0.3	GO:0036398	TCR signalosome(GO:0036398)
0.3	3.1	GO:0097431	mitotic spindle pole(GO:0097431)
0.3	1.5	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.3	0.8	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
0.3	0.8	GO:0031264	death-inducing signaling complex(GO:0031264)
0.2	7.7	GO:0030673	axolemma(GO:0030673)
0.2	10.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	1.0	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.2	4.9	GO:0042629	mast cell granule(GO:0042629)
0.2	0.7	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.2	1.5	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.2	2.2	GO:0005642	annulate lamellae(GO:0005642)
0.2	2.9	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.2	1.0	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	2.9	GO:0033643	host cell part(GO:0033643)
0.2	1.7	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.2	2.9	GO:0043219	lateral loop(GO:0043219)
0.2	0.7	GO:0005715	late recombination nodule(GO:0005715)
0.2	4.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	9.9	GO:0043198	dendritic shaft(GO:0043198)
0.2	1.6	GO:0033269	internode region of axon(GO:0033269)
0.2	1.9	GO:0005921	gap junction(GO:0005921)
0.2	4.4	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.2	0.2	GO:0031224	intrinsic component of membrane(GO:0031224)
0.2	0.7	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009) cytoplasmic side of early endosome membrane(GO:0098559)
0.2	0.9	GO:1990423	RZZ complex(GO:1990423)
0.2	0.7	GO:0031430	M band(GO:0031430)
0.2	0.5	GO:0001917	photoreceptor inner segment(GO:0001917)
0.2	2.3	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2	1.8	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.2	1.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.2	0.4	GO:1990357	terminal web(GO:1990357)
0.2	9.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	2.2	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.2	0.9	GO:0030893	meiotic cohesin complex(GO:0030893)
0.2	1.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.2	5.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	2.6	GO:0033093	Weibel-Palade body(GO:0033093)
0.2	0.9	GO:0097224	sperm connecting piece(GO:0097224)
0.2	0.4	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2	0.6	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.2	2.6	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	0.8	GO:0030891	VCB complex(GO:0030891)
0.2	10.7	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.2	2.3	GO:0030125	clathrin vesicle coat(GO:0030125)
0.2	1.0	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.2	2.1	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.2	1.0	GO:1990425	ryanodine receptor complex(GO:1990425)
0.2	0.6	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.2	1.2	GO:0070852	cell body fiber(GO:0070852)
0.2	1.0	GO:0089701	U2AF(GO:0089701)
0.2	2.8	GO:0036038	MKS complex(GO:0036038)
0.2	0.6	GO:0098536	deuterosome(GO:0098536)
0.2	0.4	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.2	0.6	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.2	1.6	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.2	2.3	GO:0030008	TRAPP complex(GO:0030008)
0.2	1.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	1.7	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.2	6.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	1.7	GO:0000439	core TFIIH complex(GO:0000439)
0.2	11.6	GO:0043195	terminal bouton(GO:0043195)
0.2	4.1	GO:0031082	BLOC complex(GO:0031082)
0.2	1.7	GO:0043218	compact myelin(GO:0043218)
0.2	0.6	GO:0030135	coated vesicle(GO:0030135)
0.2	3.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2	89.4	GO:0005925	focal adhesion(GO:0005925)
0.2	2.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2	0.7	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	2.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.2	3.1	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2	0.4	GO:0044308	axonal spine(GO:0044308)
0.2	0.5	GO:0005588	collagen type V trimer(GO:0005588)
0.2	9.8	GO:0045171	intercellular bridge(GO:0045171)
0.2	6.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	1.8	GO:0032433	filopodium tip(GO:0032433)
0.2	3.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.2	0.5	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2	1.4	GO:0035579	specific granule membrane(GO:0035579)
0.2	11.6	GO:0042734	presynaptic membrane(GO:0042734)
0.2	3.8	GO:0046930	pore complex(GO:0046930)
0.2	1.9	GO:0044463	cell projection part(GO:0044463)
0.2	3.5	GO:0001750	photoreceptor outer segment(GO:0001750)
0.2	3.3	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.2	0.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	1.3	GO:0036019	endolysosome(GO:0036019)
0.2	0.7	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.2	0.8	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2	5.0	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2	2.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.2	11.9	GO:0035580	specific granule lumen(GO:0035580)
0.2	0.3	GO:1990462	omegasome(GO:1990462)
0.2	0.2	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2	1.3	GO:0030478	actin cap(GO:0030478)
0.2	1.8	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.2	0.8	GO:0032009	early phagosome(GO:0032009)
0.2	3.9	GO:0034706	sodium channel complex(GO:0034706)
0.2	0.5	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.2	0.5	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.2	0.8	GO:0000801	central element(GO:0000801)
0.2	0.5	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.2	1.4	GO:0000125	PCAF complex(GO:0000125)
0.2	0.5	GO:0043291	RAVE complex(GO:0043291)
0.2	4.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	0.8	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	1.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.2	6.0	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	6.1	GO:0070161	adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.1	0.4	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.1	1.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	5.2	GO:0045178	basal part of cell(GO:0045178)
0.1	1.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	9.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	2.8	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	1.2	GO:0042382	paraspeckles(GO:0042382)
0.1	0.4	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.1	1.3	GO:0042599	lamellar body(GO:0042599)
0.1	0.8	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.1	GO:0042581	specific granule(GO:0042581)
0.1	1.0	GO:0005787	signal peptidase complex(GO:0005787)
0.1	1.0	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	2.9	GO:0008180	COP9 signalosome(GO:0008180)
0.1	0.4	GO:0097440	apical dendrite(GO:0097440)
0.1	0.7	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	0.4	GO:0030904	retromer complex(GO:0030904)
0.1	2.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	0.7	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.5	GO:0070695	FHF complex(GO:0070695)
0.1	0.5	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	1.5	GO:0032432	actin filament bundle(GO:0032432)
0.1	0.5	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	0.5	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	0.7	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.1	3.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.5	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.1	GO:1902710	GABA receptor complex(GO:1902710)
0.1	0.8	GO:0001740	Barr body(GO:0001740)
0.1	0.4	GO:0098553	integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1	1.9	GO:0048786	presynaptic active zone(GO:0048786)
0.1	0.4	GO:0042588	zymogen granule(GO:0042588)
0.1	2.2	GO:0034709	methylosome(GO:0034709)
0.1	1.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	1.0	GO:0005911	cell-cell junction(GO:0005911)
0.1	0.6	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	0.4	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.1	0.4	GO:0000242	pericentriolar material(GO:0000242)
0.1	8.5	GO:0070469	respiratory chain(GO:0070469)
0.1	1.8	GO:0005801	cis-Golgi network(GO:0005801)
0.1	0.5	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	25.7	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	0.4	GO:0033597	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1	0.1	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	0.7	GO:0044327	dendritic spine head(GO:0044327)
0.1	0.4	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.8	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	0.2	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.1	0.3	GO:0030677	ribonuclease P complex(GO:0030677)
0.1	0.4	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.5	GO:0031501	mannosyltransferase complex(GO:0031501)
0.1	0.5	GO:0005602	complement component C1 complex(GO:0005602)
0.1	10.5	GO:0031901	early endosome membrane(GO:0031901)
0.1	11.0	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.1	0.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.4	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.1	0.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.5	GO:0035061	interchromatin granule(GO:0035061)
0.1	1.6	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	1.0	GO:0005884	actin filament(GO:0005884)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	3.6	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	0.1	GO:0070938	contractile ring(GO:0070938)
0.1	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.6	GO:0036452	ESCRT complex(GO:0036452)
0.1	0.4	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	0.8	GO:0034464	BBSome(GO:0034464)
0.1	0.4	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.8	GO:0032039	integrator complex(GO:0032039)
0.1	0.6	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.1	0.4	GO:1904115	axon cytoplasm(GO:1904115)
0.1	0.7	GO:0043194	axon initial segment(GO:0043194)
0.1	0.6	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.2	GO:0048500	signal recognition particle(GO:0048500)
0.1	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.1	0.3	GO:0044194	cytolytic granule(GO:0044194)
0.1	0.3	GO:0000800	lateral element(GO:0000800)
0.1	0.8	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.6	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.6	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.7	GO:0005875	microtubule associated complex(GO:0005875)
0.1	0.2	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.1	0.2	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.1	1.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	7.5	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1	9.4	GO:0001726	ruffle(GO:0001726)
0.1	0.6	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.1	0.7	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.1	0.3	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.1	0.7	GO:0043073	germ cell nucleus(GO:0043073)
0.1	0.2	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.4	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	1.2	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1	2.9	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.1	1.5	GO:0030315	T-tubule(GO:0030315)
0.1	3.6	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.1	0.5	GO:0097546	ciliary base(GO:0097546)
0.1	1.5	GO:0016235	aggresome(GO:0016235)
0.1	4.4	GO:0015934	large ribosomal subunit(GO:0015934)
0.1	1.5	GO:0043209	myelin sheath(GO:0043209)
0.1	0.5	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.9	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	0.6	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.4	GO:0043196	varicosity(GO:0043196)
0.1	0.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.4	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	1.3	GO:0032420	stereocilium(GO:0032420)
0.1	1.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	1.4	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.1	1.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	0.3	GO:0032389	MutLalpha complex(GO:0032389)
0.1	0.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	0.4	GO:0016272	prefoldin complex(GO:0016272)
0.1	0.2	GO:0030314	junctional membrane complex(GO:0030314)
0.1	2.6	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	0.7	GO:0044306	neuron projection terminus(GO:0044306)
0.1	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.1	0.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.1	3.0	GO:0015030	Cajal body(GO:0015030)
0.1	0.1	GO:0000805	X chromosome(GO:0000805)
0.1	3.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	0.6	GO:0097542	ciliary tip(GO:0097542)
0.1	2.3	GO:0030175	filopodium(GO:0030175)
0.1	0.2	GO:0060198	clathrin-sculpted vesicle(GO:0060198)
0.1	0.4	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1	3.2	GO:0005811	lipid particle(GO:0005811)
0.1	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	1.1	GO:0005776	autophagosome(GO:0005776)
0.0	0.7	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0070195	growth hormone receptor complex(GO:0070195)
0.0	0.6	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	6.2	GO:0019898	extrinsic component of membrane(GO:0019898)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.4	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0032156	septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	0.8	GO:0000922	spindle pole(GO:0000922)
0.0	9.3	GO:0005874	microtubule(GO:0005874)
0.0	1.9	GO:0042641	actomyosin(GO:0042641)
0.0	0.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0071565	nBAF complex(GO:0071565)
0.0	9.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	1.8	GO:0031252	cell leading edge(GO:0031252)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.1	GO:0030894	replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0	16.6	GO:0016604	nuclear body(GO:0016604)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.0	GO:0097447	dendritic tree(GO:0097447)
0.0	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.6	GO:0043025	neuronal cell body(GO:0043025)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.4	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0032806	holo TFIIH complex(GO:0005675) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	0.9	GO:0044309	neuron spine(GO:0044309)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.3	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0070187	telosome(GO:0070187)
0.0	1.9	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.0	GO:0019814	immunoglobulin complex(GO:0019814)
0.0	0.5	GO:0005929	cilium(GO:0005929)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.0	GO:0072559	NLRP3 inflammasome complex(GO:0072559)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	0.8	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	6.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.6	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.3	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.5	GO:0072563	endothelial microparticle(GO:0072563)
1.1	4.3	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.0	2.1	GO:1990584	cardiac Troponin complex(GO:1990584)
1.0	16.3	GO:0097418	neurofibrillary tangle(GO:0097418)
0.9	3.5	GO:0043259	laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.9	11.9	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7	2.8	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.6	9.9	GO:0097512	cardiac myofibril(GO:0097512)
0.6	3.1	GO:0042643	actomyosin, actin portion(GO:0042643)
0.6	7.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6	5.5	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.5	6.5	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.4	3.9	GO:0005638	lamin filament(GO:0005638)
0.4	4.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.2	1.5	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.2	2.8	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.2	3.7	GO:0042589	zymogen granule membrane(GO:0042589)
0.2	2.7	GO:0030478	actin cap(GO:0030478)
0.2	3.3	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.2	0.5	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2	3.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	1.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	1.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	4.9	GO:0008305	integrin complex(GO:0008305)
0.1	14.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	3.0	GO:0097228	sperm principal piece(GO:0097228)
0.1	52.8	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	8.4	GO:0032587	ruffle membrane(GO:0032587)
0.1	1.5	GO:0043034	costamere(GO:0043034)
0.1	2.0	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.8	GO:0000124	SAGA complex(GO:0000124)
0.0	0.5	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	1.6	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.4	GO:0035976	AP1 complex(GO:0035976)
0.0	1.9	GO:0005771	multivesicular body(GO:0005771)
0.0	0.6	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	1.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	3.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	1.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.2	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	2.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	2.2	GO:0035579	specific granule membrane(GO:0035579)
0.0	1.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.2	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	1.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	1.9	GO:0005814	centriole(GO:0005814)
0.0	0.3	GO:0001726	ruffle(GO:0001726)
0.0	1.0	GO:0005811	lipid particle(GO:0005811)
0.0	17.5	GO:0005615	extracellular space(GO:0005615)
0.0	0.8	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	1.1	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.6	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.6	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.7	GO:0043195	terminal bouton(GO:0043195)
0.0	0.9	GO:0030175	filopodium(GO:0030175)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	5.3	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.7	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.7	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	1.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.8	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.6	GO:0005588	collagen type V trimer(GO:0005588)
0.6	1.9	GO:0070557	PCNA-p21 complex(GO:0070557)
0.6	1.8	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5	8.5	GO:0032059	bleb(GO:0032059)
0.3	1.6	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	1.3	GO:1990111	spermatoproteasome complex(GO:1990111)
0.2	2.0	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.9	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	1.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	3.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	1.0	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.6	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	2.4	GO:1904115	axon cytoplasm(GO:1904115)
0.0	5.8	GO:0005901	caveola(GO:0005901)
0.0	0.2	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	1.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.6	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.3	GO:0042599	lamellar body(GO:0042599)
0.0	1.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.5	GO:0051233	spindle midzone(GO:0051233)
0.0	0.3	GO:0030992	intraciliary transport particle B(GO:0030992)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	10.4	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.5	2.2	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	2.4	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.2	3.7	GO:0042627	chylomicron(GO:0042627)
0.2	1.2	GO:0033269	internode region of axon(GO:0033269)
0.2	0.5	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.2	1.9	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.0	GO:1990357	terminal web(GO:1990357)
0.1	1.1	GO:0005579	membrane attack complex(GO:0005579)
0.1	12.4	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	1.6	GO:0005922	connexon complex(GO:0005922)
0.1	0.4	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	0.8	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	4.9	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	0.5	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.2	GO:0043159	acrosomal matrix(GO:0043159)
0.0	2.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.5	GO:0044754	autolysosome(GO:0044754)
0.0	0.8	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.6	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.3	GO:0030897	HOPS complex(GO:0030897)
0.0	1.6	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.2	GO:0000974	Prp19 complex(GO:0000974)
0.0	2.0	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	1.9	GO:0005903	brush border(GO:0005903)
0.0	0.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0042584	chromaffin granule membrane(GO:0042584)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.0	GO:1990922	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.3	4.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.9	4.5	GO:1902728	positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.9	2.6	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.8	5.9	GO:0007256	activation of JNKK activity(GO:0007256)
0.8	4.7	GO:0071233	cellular response to leucine(GO:0071233)
0.6	1.9	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.5	0.5	GO:0046825	regulation of protein export from nucleus(GO:0046825) positive regulation of protein export from nucleus(GO:0046827)
0.5	2.0	GO:0008063	Toll signaling pathway(GO:0008063)
0.5	1.5	GO:0031133	regulation of axon diameter(GO:0031133)
0.5	0.5	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.4	1.3	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.4	1.3	GO:0071423	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.4	1.2	GO:0099545	trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.4	1.2	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4	0.4	GO:0043103	hypoxanthine salvage(GO:0043103)
0.4	1.5	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.3	1.3	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3	0.3	GO:1905245	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3	2.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.3	0.9	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) negative regulation of osteoclast proliferation(GO:0090291)
0.3	0.9	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3	1.1	GO:0071461	cellular response to redox state(GO:0071461)
0.3	0.8	GO:1903860	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.3	1.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.3	0.8	GO:0006597	spermine biosynthetic process(GO:0006597)
0.3	0.8	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3	0.8	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3	0.8	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.3	0.3	GO:0021988	olfactory lobe development(GO:0021988)
0.3	0.3	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3	1.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.2	2.0	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.2	0.5	GO:0003358	noradrenergic neuron development(GO:0003358)
0.2	0.7	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.2	1.2	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	1.0	GO:0044467	glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.2	0.5	GO:0097327	response to antineoplastic agent(GO:0097327)
0.2	1.9	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.2	2.4	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.2	0.5	GO:2001233	regulation of apoptotic signaling pathway(GO:2001233)
0.2	1.3	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.2	1.1	GO:1990834	response to odorant(GO:1990834)
0.2	1.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.2	0.9	GO:2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2	0.9	GO:0046035	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2	1.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.2	0.2	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2	0.6	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.2	0.2	GO:0043473	pigmentation(GO:0043473)
0.2	1.5	GO:1903232	melanosome assembly(GO:1903232)
0.2	0.6	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2	0.8	GO:0070982	L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.2	1.0	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.2	0.4	GO:0060018	astrocyte fate commitment(GO:0060018)
0.2	0.6	GO:0006738	nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.2	0.6	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.2	1.9	GO:0010265	SCF complex assembly(GO:0010265)
0.2	0.6	GO:1901656	glycoside transport(GO:1901656)
0.2	0.8	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2	0.7	GO:0019827	stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.2	1.8	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.2	GO:0043096	purine nucleobase salvage(GO:0043096)
0.2	0.7	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2	0.7	GO:0051958	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.2	0.4	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.2	1.3	GO:0006642	triglyceride mobilization(GO:0006642)
0.2	0.9	GO:0007070	negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.2	0.4	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2	1.6	GO:0042428	serotonin metabolic process(GO:0042428)
0.2	3.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2	0.7	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.2	0.8	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2	0.7	GO:0003409	optic cup structural organization(GO:0003409)
0.2	0.7	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2	0.7	GO:1904685	positive regulation of metalloendopeptidase activity(GO:1904685)
0.2	0.8	GO:0031126	snoRNA 3'-end processing(GO:0031126)
0.2	1.0	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.2	0.3	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.2	0.3	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.2	0.7	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.2	0.8	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.2	0.3	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.2	0.5	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.2	0.8	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.2	0.8	GO:0055064	chloride ion homeostasis(GO:0055064)
0.2	1.4	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.2	2.7	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.2	1.7	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.2	0.6	GO:0006528	asparagine metabolic process(GO:0006528)
0.2	0.5	GO:0015920	lipopolysaccharide transport(GO:0015920)
0.2	1.2	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2	1.5	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.2	1.7	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.7	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1	0.4	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	1.0	GO:0090650	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1	1.6	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.9	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	0.6	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.6	GO:2000569	T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1	0.4	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1	0.9	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.9	GO:2001171	positive regulation of ATP biosynthetic process(GO:2001171)
0.1	0.3	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.1	0.7	GO:0035617	stress granule disassembly(GO:0035617)
0.1	0.4	GO:0006272	leading strand elongation(GO:0006272)
0.1	0.4	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1	1.3	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.1	0.6	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1	0.4	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1	0.4	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.1	0.4	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.4	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.4	GO:1902227	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1	0.3	GO:1902822	regulation of late endosome to lysosome transport(GO:1902822)
0.1	0.4	GO:0031938	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1	0.4	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
0.1	0.5	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.1	GO:1901660	calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.1	0.8	GO:0021834	embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.1	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.1	5.5	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.1	0.1	GO:0003169	coronary vein morphogenesis(GO:0003169)
0.1	1.0	GO:0010993	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1	0.4	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.1	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.1	0.3	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1	0.4	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	0.4	GO:0046080	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1	0.4	GO:0008355	olfactory learning(GO:0008355)
0.1	0.6	GO:0071105	response to interleukin-11(GO:0071105)
0.1	0.4	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.1	1.4	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.1	1.1	GO:0015791	polyol transport(GO:0015791)
0.1	0.1	GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1	0.4	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1	0.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.1	0.5	GO:0072302	posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1	0.7	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.1	0.4	GO:0021919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1	0.5	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1	0.6	GO:1902904	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.5	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1	0.4	GO:0032765	positive regulation of mast cell cytokine production(GO:0032765)
0.1	0.8	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.1	0.1	GO:0002088	lens development in camera-type eye(GO:0002088)
0.1	0.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.8	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	0.6	GO:0002084	protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.8	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.5	GO:0000432	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1	0.3	GO:0072560	glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1	0.4	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1	0.6	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
0.1	0.4	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	0.4	GO:0070384	Harderian gland development(GO:0070384)
0.1	0.3	GO:0021586	pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1	0.4	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.4	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.7	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.1	0.3	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1	1.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	1.9	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.1	1.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.1	0.3	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.4	GO:0009386	translational attenuation(GO:0009386)
0.1	0.7	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1	1.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.5	GO:0034971	regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971)
0.1	0.7	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.1	0.4	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.1	0.1	GO:0046016	positive regulation of transcription by glucose(GO:0046016)
0.1	0.6	GO:0051013	microtubule severing(GO:0051013)
0.1	0.1	GO:0040031	snRNA modification(GO:0040031)
0.1	0.7	GO:1902915	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	1.2	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.1	0.6	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.4	GO:0019322	pentose biosynthetic process(GO:0019322)
0.1	0.3	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	1.5	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.1	0.3	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.6	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.1	0.6	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.3	GO:0070541	response to platinum ion(GO:0070541)
0.1	0.9	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.1	0.3	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.5	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.3	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.1	0.2	GO:0032289	central nervous system myelin formation(GO:0032289) positive regulation of gastrulation(GO:2000543)
0.1	0.4	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.7	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.3	GO:0060013	righting reflex(GO:0060013)
0.1	0.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.5	GO:0061146	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1	1.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.3	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.6	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	3.1	GO:0007616	long-term memory(GO:0007616)
0.1	0.7	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.4	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.2	GO:0060535	trachea cartilage morphogenesis(GO:0060535)
0.1	0.4	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.1	0.3	GO:0006106	fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.1	0.6	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	0.4	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1	0.5	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.1	1.0	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.1	1.2	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.1	0.3	GO:1903926	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1	0.3	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1	0.3	GO:0045773	positive regulation of axon extension(GO:0045773)
0.1	1.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.3	GO:2000410	regulation of thymocyte migration(GO:2000410)
0.1	0.8	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	0.9	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.3	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	0.4	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1	0.3	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1	0.1	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.1	0.4	GO:0035524	proline transmembrane transport(GO:0035524)
0.1	0.7	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.7	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.1	1.1	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1	0.5	GO:1902570	protein localization to nucleolus(GO:1902570)
0.1	0.2	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.8	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.1	0.4	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.5	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	0.2	GO:1903939	regulation of TORC2 signaling(GO:1903939)
0.1	0.4	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.1	4.9	GO:0008542	visual learning(GO:0008542)
0.1	0.2	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1	0.1	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.9	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	0.9	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	2.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.2	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	1.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	5.8	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.1	0.2	GO:0036071	N-glycan fucosylation(GO:0036071)
0.1	3.9	GO:0043486	histone exchange(GO:0043486)
0.1	0.5	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.2	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	2.7	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	1.1	GO:1904152	regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.1	0.5	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.2	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.2	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.2	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.1	0.2	GO:0060152	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1	0.6	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.1	0.3	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.1	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.1	0.5	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1	0.5	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.1	0.3	GO:0000101	sulfur amino acid transport(GO:0000101)
0.1	0.5	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.7	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.1	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1	0.4	GO:0060017	parathyroid gland development(GO:0060017)
0.1	0.3	GO:0048539	bone marrow development(GO:0048539)
0.1	0.4	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.1	0.2	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.1	1.9	GO:0030488	tRNA methylation(GO:0030488)
0.1	1.2	GO:0016180	snRNA processing(GO:0016180)
0.1	0.2	GO:0072014	proximal tubule development(GO:0072014)
0.1	0.2	GO:0006788	heme oxidation(GO:0006788)
0.1	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.4	GO:0015853	adenine transport(GO:0015853)
0.1	0.1	GO:1904872	regulation of telomerase RNA localization to Cajal body(GO:1904872)
0.1	1.2	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.1	0.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.2	GO:0070093	negative regulation of glucagon secretion(GO:0070093)
0.1	0.6	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	1.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.2	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.1	1.0	GO:0015671	oxygen transport(GO:0015671)
0.1	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.1	0.3	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	0.5	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	0.1	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
0.1	0.5	GO:0030578	PML body organization(GO:0030578)
0.1	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.1	0.3	GO:1904588	cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.1	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.5	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.1	0.2	GO:1901355	response to rapamycin(GO:1901355)
0.1	0.9	GO:1904869	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.1	0.5	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.2	GO:0046061	dATP catabolic process(GO:0046061)
0.1	0.7	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.1	0.2	GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1	0.8	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) proton-transporting two-sector ATPase complex assembly(GO:0070071) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.2	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	0.2	GO:0048627	myoblast development(GO:0048627)
0.1	0.4	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1	1.5	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	0.4	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1	0.2	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	1.3	GO:0038202	TORC1 signaling(GO:0038202)
0.1	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.1	0.4	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	0.4	GO:0045007	depurination(GO:0045007)
0.1	0.4	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.2	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.1	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.1	0.2	GO:1990519	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1	0.1	GO:0007043	cell-cell junction assembly(GO:0007043)
0.1	1.1	GO:0046330	positive regulation of JNK cascade(GO:0046330)
0.1	0.5	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.1	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	1.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.2	GO:0072308	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1	0.5	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.2	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.2	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.1	0.2	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	0.2	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.1	0.4	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1	0.5	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.2	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.1	0.2	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	0.2	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	0.1	GO:1990535	neuron projection maintenance(GO:1990535)
0.1	0.2	GO:0035546	interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.1	0.8	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	0.2	GO:0070781	response to biotin(GO:0070781)
0.1	0.3	GO:2001300	lipoxin metabolic process(GO:2001300)
0.1	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.3	GO:0021759	globus pallidus development(GO:0021759)
0.1	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.6	GO:0048302	isotype switching to IgG isotypes(GO:0048291) regulation of isotype switching to IgG isotypes(GO:0048302)
0.1	0.1	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
0.1	0.2	GO:1904874	positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.1	0.4	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	0.2	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.1	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	0.3	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.2	GO:0000012	single strand break repair(GO:0000012)
0.1	0.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.5	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.1	GO:0043633	polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.1	0.2	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
0.1	0.7	GO:0097264	self proteolysis(GO:0097264)
0.1	2.9	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.1	0.8	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1	0.1	GO:0019858	cytosine metabolic process(GO:0019858)
0.1	0.3	GO:0042816	vitamin B6 metabolic process(GO:0042816)
0.1	0.2	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.1	0.1	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1	0.2	GO:0002904	immature B cell differentiation(GO:0002327) positive regulation of B cell apoptotic process(GO:0002904)
0.1	0.2	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.1	0.3	GO:0036337	Fas signaling pathway(GO:0036337)
0.1	0.2	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1	0.2	GO:0035411	catenin import into nucleus(GO:0035411)
0.1	0.2	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.1	GO:1901160	primary amino compound metabolic process(GO:1901160)
0.1	0.6	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.5	GO:1904779	regulation of protein localization to centrosome(GO:1904779)
0.1	0.1	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.6	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.1	1.1	GO:0006312	mitotic recombination(GO:0006312)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.3	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.5	GO:0006582	melanin metabolic process(GO:0006582)
0.0	1.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	1.6	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	1.2	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.0	0.8	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.9	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	1.3	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	1.1	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.0	0.5	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.0	0.9	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.4	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.1	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.0	0.4	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.7	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	1.8	GO:0006101	citrate metabolic process(GO:0006101)
0.0	2.0	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.5	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.3	GO:0035799	ureter maturation(GO:0035799)
0.0	0.2	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	0.3	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.2	GO:0010628	positive regulation of gene expression(GO:0010628)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.2	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.0	GO:0098877	neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) protein localization to postsynaptic membrane(GO:1903539) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0	0.6	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.0	0.4	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.3	GO:0021794	thalamus development(GO:0021794)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0019860	uracil metabolic process(GO:0019860)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.0	0.1	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	1.3	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0051036	regulation of endosome size(GO:0051036)
0.0	0.8	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.3	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.2	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.4	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.0	0.3	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.1	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.0	0.1	GO:2000401	regulation of lymphocyte migration(GO:2000401)
0.0	0.3	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.4	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	0.1	GO:0035350	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0	0.4	GO:0043174	nucleoside salvage(GO:0043174)
0.0	0.2	GO:1904816	regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0	0.1	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0	0.2	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.4	GO:0010663	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.2	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	0.7	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.3	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0	0.5	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0042756	drinking behavior(GO:0042756)
0.0	0.2	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0	0.1	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0	0.2	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.1	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.1	GO:2000364	regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0	1.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.4	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.4	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:1902047	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0012502	induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0	0.1	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.8	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.1	GO:0032661	regulation of interleukin-18 production(GO:0032661) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.4	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	0.2	GO:0006021	inositol biosynthetic process(GO:0006021)
0.0	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:0023035	CD40 signaling pathway(GO:0023035)
0.0	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.4	GO:0030238	male sex determination(GO:0030238)
0.0	0.3	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.2	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:0015680	intracellular copper ion transport(GO:0015680)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.2	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.3	GO:0097107	postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) excitatory synapse assembly(GO:1904861)
0.0	0.4	GO:0010826	negative regulation of centrosome duplication(GO:0010826)
0.0	0.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.0	0.9	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0	0.5	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.1	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.0	0.1	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0033341	regulation of collagen binding(GO:0033341)
0.0	0.4	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.3	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.2	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0035564	regulation of kidney size(GO:0035564) regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623) pronephros morphogenesis(GO:0072114)
0.0	0.4	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0034776	response to histamine(GO:0034776)
0.0	0.2	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.4	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.1	GO:0090045	positive regulation of deacetylase activity(GO:0090045)
0.0	0.2	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.5	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.0	0.2	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	0.7	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.4	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.3	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.0	0.3	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.5	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.5	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.5	GO:2000757	negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.6	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.0	0.1	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.1	GO:0035470	positive regulation of vascular wound healing(GO:0035470)
0.0	0.1	GO:0042369	vitamin D catabolic process(GO:0042369)
0.0	0.1	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0051885	positive regulation of anagen(GO:0051885)
0.0	0.4	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.9	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0090212	regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0	0.2	GO:1903333	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.0	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0	0.1	GO:0046929	negative regulation of neurotransmitter secretion(GO:0046929)
0.0	0.2	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.2	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.8	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.5	GO:0014823	response to activity(GO:0014823)
0.0	0.2	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.3	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.4	GO:2000678	negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.1	GO:1901725	histone H3-K4 demethylation(GO:0034720) regulation of histone deacetylase activity(GO:1901725)
0.0	0.1	GO:0072709	cellular response to sorbitol(GO:0072709)
0.0	0.8	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:0048867	stem cell fate determination(GO:0048867)
0.0	0.2	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	0.1	GO:1901993	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	1.7	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.1	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.3	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.0	GO:1990910	response to hypobaric hypoxia(GO:1990910)
0.0	0.0	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.0	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.0	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0	0.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.4	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.2	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.3	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.4	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.0	0.2	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0	0.1	GO:0046203	spermidine catabolic process(GO:0046203)
0.0	0.4	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.2	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.4	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0002678	chronic inflammatory response to non-antigenic stimulus(GO:0002545) positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.0	0.6	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.2	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	1.5	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.0	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.2	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.5	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0	0.1	GO:0098761	interleukin-7-mediated signaling pathway(GO:0038111) response to interleukin-7(GO:0098760) cellular response to interleukin-7(GO:0098761)
0.0	0.9	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.2	GO:0000732	strand displacement(GO:0000732)
0.0	0.1	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0044030	regulation of DNA methylation(GO:0044030)
0.0	0.4	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.0	0.2	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	1.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.7	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.4	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.3	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.6	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.5	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.2	GO:0035065	regulation of histone acetylation(GO:0035065)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0006581	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0	0.9	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.3	GO:0072348	sulfur compound transport(GO:0072348)
0.0	0.0	GO:0021938	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.4	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	1.9	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.3	GO:0000154	rRNA modification(GO:0000154)
0.0	0.3	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.0	GO:0036269	swimming behavior(GO:0036269)
0.0	0.6	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.3	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.0	0.6	GO:0031058	positive regulation of histone modification(GO:0031058)
0.0	0.2	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.9	GO:0008033	tRNA processing(GO:0008033)
0.0	0.3	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.2	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0	0.1	GO:0007379	segment specification(GO:0007379)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.9	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.4	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.1	GO:0042262	DNA protection(GO:0042262)
0.0	0.2	GO:0036035	osteoclast development(GO:0036035)
0.0	0.0	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.0	0.1	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.2	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.2	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.7	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.3	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.2	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.3	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.1	GO:0010898	regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.3	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.0	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.0	GO:0007440	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.1	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0	0.3	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.0	GO:0031291	Ran protein signal transduction(GO:0031291)
0.0	0.0	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.4	GO:0097503	sialylation(GO:0097503)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.0	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.2	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:0048511	rhythmic process(GO:0048511)
0.0	0.1	GO:0032310	prostaglandin secretion(GO:0032310)
0.0	0.3	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.0	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0	0.1	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.3	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.0	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.2	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	0.1	GO:1903826	arginine transmembrane transport(GO:1903826)
0.0	0.0	GO:0071863	regulation of cell proliferation in bone marrow(GO:0071863) positive regulation of cell proliferation in bone marrow(GO:0071864)
0.0	0.0	GO:0070837	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0	0.0	GO:0060215	primitive hemopoiesis(GO:0060215)
0.0	0.3	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0061724	lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.1	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.4	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.0	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.0	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0	0.1	GO:0001764	neuron migration(GO:0001764)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0042350	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0	0.0	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.0	0.0	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0	0.0	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.2	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.2	GO:0042632	cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.3	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.5	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.5	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0008344	adult locomotory behavior(GO:0008344)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.4	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:1900449	regulation of glutamate receptor signaling pathway(GO:1900449)
0.0	0.5	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0035811	negative regulation of urine volume(GO:0035811)
0.0	0.3	GO:0010259	multicellular organism aging(GO:0010259)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:0006298	mismatch repair(GO:0006298)
0.0	0.6	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.1	GO:0051444	negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0	0.0	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.1	GO:0090003	regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0	0.1	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.0	GO:1904587	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) response to glycoprotein(GO:1904587)
0.0	0.1	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.0	GO:0002183	cytoplasmic translational initiation(GO:0002183)
0.0	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:1901094	protein import into peroxisome matrix, docking(GO:0016560) regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0	0.0	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496) regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0	0.0	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.2	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.3	GO:0009261	purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261)
0.0	0.1	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.5	GO:0032090	Pyrin domain binding(GO:0032090)
1.3	3.9	GO:0004832	valine-tRNA ligase activity(GO:0004832)
1.0	5.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.9	5.4	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.9	2.6	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.7	2.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.6	1.9	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.6	1.7	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.5	7.4	GO:0031014	troponin T binding(GO:0031014)
0.5	1.6	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.5	1.5	GO:0003883	CTP synthase activity(GO:0003883)
0.5	2.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5	8.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.4	1.2	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.4	1.1	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.3	0.7	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.3	3.3	GO:0019237	centromeric DNA binding(GO:0019237)
0.3	1.5	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3	4.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.3	0.8	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3	0.8	GO:0004766	spermidine synthase activity(GO:0004766)
0.3	0.8	GO:0032551	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.3	1.3	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2	0.7	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.2	0.7	GO:0001003	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.2	3.3	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.2	0.5	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2	0.9	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.2	0.4	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.2	0.8	GO:0047718	indanol dehydrogenase activity(GO:0047718)
0.2	1.2	GO:0043199	sulfate binding(GO:0043199)
0.2	0.6	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2	0.7	GO:0016936	galactoside binding(GO:0016936)
0.2	0.5	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.2	1.2	GO:0030621	U4 snRNA binding(GO:0030621)
0.2	0.7	GO:0005502	11-cis retinal binding(GO:0005502)
0.2	1.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.2	0.5	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.2	0.5	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2	6.9	GO:0050699	WW domain binding(GO:0050699)
0.2	1.7	GO:0051525	NFAT protein binding(GO:0051525)
0.2	0.5	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2	0.5	GO:0004913	interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.1	0.6	GO:0052794	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	1.3	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	1.4	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
0.1	0.4	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	1.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	1.0	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.7	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	0.4	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.4	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1	1.4	GO:0009374	biotin binding(GO:0009374)
0.1	0.5	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.1	0.7	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1	0.9	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.4	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	1.7	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.4	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	2.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.7	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	1.3	GO:0008430	selenium binding(GO:0008430)
0.1	1.4	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	0.5	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.9	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	0.3	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.5	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	1.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.4	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1	0.4	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.3	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1	1.8	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	1.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.4	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	1.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	0.8	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.6	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.1	1.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.6	GO:0004623	phospholipase A2 activity(GO:0004623)
0.1	0.7	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	0.4	GO:0042020	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1	0.4	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.1	0.6	GO:0000182	rDNA binding(GO:0000182)
0.1	0.3	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.9	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.5	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.3	GO:0030375	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.7	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1	0.7	GO:0004064	arylesterase activity(GO:0004064)
0.1	1.4	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	2.4	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.6	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.4	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.1	0.5	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.1	0.2	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1	0.6	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.7	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.5	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.7	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.1	0.7	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	2.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	0.2	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	0.3	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	1.4	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	0.4	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	0.4	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.3	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.1	0.2	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.1	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.3	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1	0.6	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.5	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	0.9	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.5	GO:0008172	S-methyltransferase activity(GO:0008172)
0.1	0.1	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1	0.2	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.1	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	0.2	GO:0004335	galactokinase activity(GO:0004335)
0.1	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	0.2	GO:0017130	poly(C) RNA binding(GO:0017130)
0.1	0.2	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.1	1.1	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.1	0.6	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.1	0.7	GO:0015926	glucosidase activity(GO:0015926)
0.1	0.3	GO:0070905	serine binding(GO:0070905)
0.1	0.3	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	0.8	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.2	GO:0071253	connexin binding(GO:0071253)
0.1	0.8	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1	0.2	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.3	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.1	0.4	GO:1990446	U1 snRNP binding(GO:1990446)
0.1	0.5	GO:0035174	histone serine kinase activity(GO:0035174)
0.1	0.8	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.4	GO:1990763	arrestin family protein binding(GO:1990763)
0.1	2.6	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.1	1.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.3	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.3	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.9	GO:0019864	IgG binding(GO:0019864)
0.0	0.3	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.2	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.2	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.4	GO:0030249	cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0	0.5	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.2	GO:0047708	biotinidase activity(GO:0047708)
0.0	0.4	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.7	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0099609	microtubule lateral binding(GO:0099609)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.7	GO:0043295	glutathione binding(GO:0043295)
0.0	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0001855	complement component C4b binding(GO:0001855)
0.0	0.2	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.0	0.0	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	1.0	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.7	GO:0070628	proteasome binding(GO:0070628)
0.0	0.5	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.3	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	1.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	2.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.2	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	1.1	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:0002046	opsin binding(GO:0002046)
0.0	1.0	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.5	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.2	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	1.2	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.7	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	4.5	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.7	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.4	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.2	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.4	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.2	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.2	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.7	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.3	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.3	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	0.1	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.9	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.3	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.4	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.4	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.7	GO:0001848	complement binding(GO:0001848)
0.0	1.0	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.6	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.9	GO:0001671	ATPase activator activity(GO:0001671)
0.0	1.0	GO:0004532	exoribonuclease activity(GO:0004532)
0.0	0.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.9	GO:0004536	deoxyribonuclease activity(GO:0004536)
0.0	1.8	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.3	GO:0004969	histamine receptor activity(GO:0004969)
0.0	1.2	GO:0004386	helicase activity(GO:0004386)
0.0	17.9	GO:0003712	transcription cofactor activity(GO:0003712)
0.0	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.4	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.9	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.4	GO:0010181	FMN binding(GO:0010181)
0.0	0.8	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.3	GO:0022842	leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0	0.5	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	1.5	GO:0019843	rRNA binding(GO:0019843)
0.0	0.4	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.5	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.2	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.7	GO:0004540	ribonuclease activity(GO:0004540)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	1.2	GO:0042393	histone binding(GO:0042393)
0.0	0.4	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.6	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	2.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.5	GO:0001972	retinoic acid binding(GO:0001972)
0.0	3.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.0	GO:0016297	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.0	2.0	GO:0005179	hormone activity(GO:0005179)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	1.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	1.8	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.2	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.5	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.0	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0	0.4	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.0	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0032217	riboflavin transporter activity(GO:0032217)
0.0	2.7	GO:0061659	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.4	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.6	GO:0002039	p53 binding(GO:0002039)
0.0	0.3	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.0	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.0	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.5	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.9	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.1	GO:0015144	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	10.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.5	40.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	1.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	5.5	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	4.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	1.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	3.1	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	1.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	32.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.5	11.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.4	4.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4	10.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	5.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	5.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	5.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.2	5.8	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	5.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.2	0.4	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.2	17.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	12.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	2.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	2.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	3.3	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	2.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	2.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	0.6	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	1.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	3.0	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	5.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.0	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1	1.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	4.0	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.6	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.9	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	2.5	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.1	3.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	5.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	0.7	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	1.9	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	0.9	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	3.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	5.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	1.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.7	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	2.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	2.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	0.8	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.1	3.5	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	0.6	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	2.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	3.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	1.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	1.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	1.7	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	5.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	2.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	2.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.9	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	5.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1	1.6	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME DEFENSINS	Genes involved in Defensins
0.0	1.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.9	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	2.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	5.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.9	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.5	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	1.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.8	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.6	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.9	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	4.7	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.6	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	3.2	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.7	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	1.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.6	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	1.2	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	1.3	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	1.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.6	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.0	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.5	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.3	GO:0033063	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	5.1	GO:0035579	specific granule membrane(GO:0035579)
0.0	1.9	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.4	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	3.0	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.2	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.1	GO:0043596	nuclear replication fork(GO:0043596)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	7.0	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2	4.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.0	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	2.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	0.1	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.1	0.8	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.6	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.6	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	2.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.6	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.4	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.6	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.4	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	34.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.7	35.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.4	5.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.3	5.8	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.3	7.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	4.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	12.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	5.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	4.9	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.2	5.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	6.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	2.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	3.0	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	2.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	6.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	1.0	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	3.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	2.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.6	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.9	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.5	0.9	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.5	1.8	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.4	2.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.4	0.4	GO:0001740	Barr body(GO:0001740)
0.4	2.9	GO:0060091	kinocilium(GO:0060091)
0.4	1.2	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.4	1.5	GO:0032301	MutSalpha complex(GO:0032301)
0.4	1.8	GO:0005726	perichromatin fibrils(GO:0005726)
0.4	1.4	GO:0033186	CAF-1 complex(GO:0033186)
0.3	2.1	GO:0061689	tricellular tight junction(GO:0061689)
0.3	2.0	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.3	4.0	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3	2.2	GO:0001520	outer dense fiber(GO:0001520)
0.3	0.8	GO:0043291	RAVE complex(GO:0043291)
0.3	1.5	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	2.3	GO:0001739	sex chromatin(GO:0001739)
0.2	0.7	GO:0098536	deuterosome(GO:0098536)
0.2	5.3	GO:0071564	npBAF complex(GO:0071564)
0.2	0.7	GO:0030689	Noc complex(GO:0030689)
0.2	0.7	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.2	1.5	GO:0031415	NatA complex(GO:0031415)
0.2	0.8	GO:0016514	SWI/SNF complex(GO:0016514)
0.2	4.1	GO:0000812	Swr1 complex(GO:0000812)
0.2	0.6	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2	0.6	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.2	1.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.2	9.8	GO:0000786	nucleosome(GO:0000786)
0.2	1.4	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2	2.0	GO:0005642	annulate lamellae(GO:0005642)
0.2	1.2	GO:0090544	BAF-type complex(GO:0090544)
0.2	0.6	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.2	0.5	GO:0005663	DNA replication factor C complex(GO:0005663)
0.2	1.4	GO:0032039	integrator complex(GO:0032039)
0.1	1.0	GO:0097452	GAIT complex(GO:0097452)
0.1	0.6	GO:1990423	RZZ complex(GO:1990423)
0.1	1.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	0.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	1.0	GO:0061617	MICOS complex(GO:0061617)
0.1	1.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	1.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	1.7	GO:0000815	ESCRT III complex(GO:0000815)
0.1	1.3	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	0.6	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.1	1.0	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	1.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.1	0.8	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	0.9	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.1	0.9	GO:0031298	replication fork protection complex(GO:0031298)
0.1	1.6	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	1.0	GO:0042555	MCM complex(GO:0042555)
0.1	0.4	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	1.2	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	1.7	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.7	GO:0030893	meiotic cohesin complex(GO:0030893)
0.1	0.4	GO:0035061	interchromatin granule(GO:0035061)
0.1	1.6	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	0.4	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	1.4	GO:0008091	spectrin(GO:0008091)
0.1	0.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	1.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	2.9	GO:0070461	SAGA-type complex(GO:0070461)
0.1	0.9	GO:0042587	glycogen granule(GO:0042587)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.7	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	1.0	GO:0045120	pronucleus(GO:0045120)
0.1	0.5	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.1	0.8	GO:0097427	microtubule bundle(GO:0097427)
0.1	1.3	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.4	GO:0001652	granular component(GO:0001652)
0.1	2.0	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	0.3	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.3	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.5	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	10.0	GO:0016363	nuclear matrix(GO:0016363)
0.1	0.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	3.5	GO:0000792	heterochromatin(GO:0000792)
0.1	0.2	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	0.7	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	0.5	GO:0070187	telosome(GO:0070187)
0.1	0.3	GO:0097149	centralspindlin complex(GO:0097149)
0.1	0.5	GO:0070552	BRISC complex(GO:0070552)
0.1	1.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	0.2	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
0.1	0.5	GO:0005688	U6 snRNP(GO:0005688)
0.1	0.8	GO:0005686	U2 snRNP(GO:0005686)
0.1	4.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.2	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.1	0.9	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	5.9	GO:0016605	PML body(GO:0016605)
0.1	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.4	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1	0.4	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	1.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.4	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.4	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.2	GO:0005846	nuclear cap binding complex(GO:0005846)
0.0	0.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.6	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	1.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.4	GO:0044815	DNA packaging complex(GO:0044815)
0.0	0.4	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.8	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0	0.1	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.7	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	2.1	GO:0016235	aggresome(GO:0016235)
0.0	0.4	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	2.4	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.0	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.6	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	1.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.2	GO:0097542	ciliary tip(GO:0097542)
0.0	1.9	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.3	GO:0005827	polar microtubule(GO:0005827)
0.0	1.2	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	1.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.6	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	1.2	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.4	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0032807	DNA ligase IV complex(GO:0032807)
0.0	0.5	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.5	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.0	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.9	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.9	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.3	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.9	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.6	GO:0032420	stereocilium(GO:0032420)
0.0	0.2	GO:0097227	sperm annulus(GO:0097227)
0.0	0.3	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	8.0	GO:0000785	chromatin(GO:0000785)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.9	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.6	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	1.0	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.9	GO:0032587	ruffle membrane(GO:0032587)
0.0	1.2	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	1.8	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.4	GO:0032433	filopodium tip(GO:0032433)
0.0	0.3	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.0	0.4	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.8	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.4	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0005652	lamin filament(GO:0005638) nuclear lamina(GO:0005652)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0097449	astrocyte projection(GO:0097449)
0.0	0.8	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.2	GO:0097440	apical dendrite(GO:0097440)
0.0	0.2	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.4	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.8	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.2	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.2	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	12.8	GO:0005730	nucleolus(GO:0005730)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.4	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	1.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.5	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.9	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.9	GO:0005814	centriole(GO:0005814)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.4	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.4	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.0	GO:0031213	RSF complex(GO:0031213)
0.0	0.0	GO:0043296	apical junction complex(GO:0043296)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	2.8	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.4	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.6	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	11.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.5	7.3	GO:0042289	MHC class II protein binding(GO:0042289)
1.1	4.6	GO:0016880	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.7	7.4	GO:0039706	co-receptor binding(GO:0039706)
0.7	2.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.6	10.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	5.7	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.5	2.9	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.5	1.9	GO:0047718	enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.4	1.3	GO:0070699	type II activin receptor binding(GO:0070699)
0.4	1.6	GO:0015254	glycerol channel activity(GO:0015254)
0.4	0.7	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3	2.4	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	2.3	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.3	4.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.3	3.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.3	1.9	GO:0070492	oligosaccharide binding(GO:0070492)
0.3	3.6	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	2.0	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	1.3	GO:1990254	keratin filament binding(GO:1990254)
0.2	2.3	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	1.0	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.2	0.6	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.2	1.5	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.2	0.7	GO:0004743	pyruvate kinase activity(GO:0004743)
0.2	0.5	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.2	0.5	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	1.3	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	5.0	GO:0042056	chemoattractant activity(GO:0042056)
0.1	1.5	GO:0045159	myosin II binding(GO:0045159)
0.1	1.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	2.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	2.8	GO:0017081	chloride channel regulator activity(GO:0017081)
0.1	18.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.3	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.3	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1	13.4	GO:0002020	protease binding(GO:0002020)
0.1	0.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	1.6	GO:0070628	proteasome binding(GO:0070628)
0.1	1.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.1	2.7	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	1.0	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	0.5	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	0.4	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	1.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	6.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.5	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	3.5	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	0.5	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.8	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.5	GO:0097016	L27 domain binding(GO:0097016)
0.0	4.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.7	GO:0016918	retinal binding(GO:0016918)
0.0	0.3	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.7	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	3.2	GO:0050681	androgen receptor binding(GO:0050681)
0.0	1.3	GO:0005109	frizzled binding(GO:0005109)
0.0	10.3	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.2	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.2	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.0	0.1	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
0.0	1.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.3	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	28.3	GO:0008270	zinc ion binding(GO:0008270)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	2.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	18.3	GO:0005198	structural molecule activity(GO:0005198)
0.0	1.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	1.7	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	1.1	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.0	1.2	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.7	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.6	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	4.9	GO:0003924	GTPase activity(GO:0003924)
0.0	0.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	1.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	1.5	GO:0019905	syntaxin binding(GO:0019905)
0.0	2.0	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.5	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.5	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.9	GO:0051087	chaperone binding(GO:0051087)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0044326	dendritic spine neck(GO:0044326)
0.1	0.9	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	0.6	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.1	2.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.6	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	1.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.6	GO:0031415	NatA complex(GO:0031415)
0.1	1.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	1.8	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	0.3	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.2	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.0	0.4	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.1	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	0.8	GO:0097342	ripoptosome(GO:0097342)
0.0	0.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.9	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.4	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.3	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.4	GO:1990023	kinetochore microtubule(GO:0005828) mitotic spindle midzone(GO:1990023)
0.0	0.3	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.3	GO:0097255	R2TP complex(GO:0097255)
0.0	0.2	GO:0070938	contractile ring(GO:0070938)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.6	GO:0032982	myosin filament(GO:0032982)
0.0	0.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	2.3	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.1	GO:0033010	paranodal junction(GO:0033010)
0.0	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.2	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.5	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0090543	Flemming body(GO:0090543)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.2	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.4	2.6	GO:1904729	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.3	1.0	GO:0046521	sphingoid catabolic process(GO:0046521)
0.3	2.0	GO:0098707	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3	3.5	GO:0043249	erythrocyte maturation(GO:0043249)
0.3	2.6	GO:0001955	blood vessel maturation(GO:0001955)
0.2	0.7	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2	0.4	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.2	0.9	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.9	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.1	0.7	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.4	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	3.2	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	0.3	GO:1900195	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.1	1.1	GO:0034378	chylomicron assembly(GO:0034378)
0.1	1.3	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1	1.4	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.2	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	1.2	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1	1.0	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.7	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	2.2	GO:0015695	organic cation transport(GO:0015695)
0.1	0.3	GO:1902612	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1	1.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	1.2	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.0	0.2	GO:0046882	negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.6	GO:0002003	angiotensin maturation(GO:0002003)
0.0	1.1	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	1.5	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.0	3.8	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.3	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.0	1.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.2	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.2	REACTOME AMYLOIDS	Genes involved in Amyloids

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
1.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
1.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.9	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	3.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	1.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	4.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	4.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.7	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.6	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.3	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	4.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.8	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.1	PID CMYB PATHWAY	C-MYB transcription factor network

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.4	3.0	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2	1.1	GO:1902896	terminal web assembly(GO:1902896)
0.2	0.6	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	0.4	GO:0098759	response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1	0.6	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.1	0.2	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	0.5	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.4	GO:0035803	egg coat formation(GO:0035803)
0.1	0.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1	0.9	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1	2.3	GO:0007398	ectoderm development(GO:0007398)
0.1	0.8	GO:0051451	myoblast migration(GO:0051451)
0.1	0.8	GO:0019388	galactose catabolic process(GO:0019388)
0.1	0.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.3	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.0	0.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.5	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.3	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.2	GO:1900175	regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.0	0.1	GO:0045210	negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.0	1.5	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.3	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.5	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.2	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0	0.4	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.2	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.1	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.0	0.2	GO:0015747	urate transport(GO:0015747)
0.0	0.4	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.0	0.5	GO:0051923	sulfation(GO:0051923)
0.0	0.2	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	0.8	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	0.9	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	4.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.7	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.8	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	6.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.2	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.9	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.7	PID LKB1 PATHWAY	LKB1 signaling events

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.2	GO:0005588	collagen type V trimer(GO:0005588)
1.2	18.8	GO:0097418	neurofibrillary tangle(GO:0097418)
0.9	13.7	GO:0030478	actin cap(GO:0030478)
0.9	4.3	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.8	8.7	GO:0005614	interstitial matrix(GO:0005614)
0.6	2.5	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.6	1.8	GO:0070435	Shc-EGFR complex(GO:0070435)
0.5	3.8	GO:0036021	endolysosome lumen(GO:0036021)
0.3	3.7	GO:0097443	sorting endosome(GO:0097443)
0.3	1.6	GO:0001652	granular component(GO:0001652)
0.3	5.3	GO:0032059	bleb(GO:0032059)
0.3	3.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	3.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.6	GO:0002081	outer acrosomal membrane(GO:0002081)
0.2	2.4	GO:0031089	platelet dense granule lumen(GO:0031089)
0.1	1.9	GO:0097227	sperm annulus(GO:0097227)
0.1	1.3	GO:0071953	elastic fiber(GO:0071953)
0.1	6.8	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	0.8	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1	4.4	GO:0000421	autophagosome membrane(GO:0000421)
0.1	0.6	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.5	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	1.3	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:1990015	mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1	1.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.4	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.6	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	3.7	GO:0031430	M band(GO:0031430)
0.1	8.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	1.3	GO:0031143	pseudopodium(GO:0031143)
0.1	0.4	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	0.4	GO:0005602	complement component C1 complex(GO:0005602)
0.1	0.8	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.3	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.8	GO:0008091	spectrin(GO:0008091)
0.1	0.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.3	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.1	0.7	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1	0.2	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	0.7	GO:0043194	axon initial segment(GO:0043194)
0.1	0.5	GO:0005579	membrane attack complex(GO:0005579)
0.1	2.4	GO:0031941	filamentous actin(GO:0031941)
0.0	1.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0033269	internode region of axon(GO:0033269)
0.0	1.4	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.7	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.3	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0	0.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.8	GO:0000145	exocyst(GO:0000145)
0.0	0.6	GO:0036038	MKS complex(GO:0036038)
0.0	0.4	GO:0005915	zonula adherens(GO:0005915)
0.0	1.2	GO:0030133	transport vesicle(GO:0030133)
0.0	1.9	GO:0002102	podosome(GO:0002102)
0.0	0.7	GO:0097342	ripoptosome(GO:0097342)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0031673	H zone(GO:0031673)
0.0	1.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	3.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.5	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.6	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	10.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	1.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	2.8	GO:0044216	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	1.0	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0016938	kinesin I complex(GO:0016938)
0.0	0.5	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	2.1	GO:0005901	caveola(GO:0005901)
0.0	4.3	GO:0030016	myofibril(GO:0030016)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.4	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0000806	Y chromosome(GO:0000806)
0.0	0.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.6	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	1.6	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.1	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0	1.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.4	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	1.1	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.5	GO:0016528	sarcoplasm(GO:0016528)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.8	GO:0005811	lipid particle(GO:0005811)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	3.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	6.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	4.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	0.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	2.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.9	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.4	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.8	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	3.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	2.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	2.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	0.7	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	4.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	2.3	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.9	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	1.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	6.4	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
1.3	4.0	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.1	4.4	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.0	28.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.9	3.7	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.9	3.4	GO:0050712	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.8	3.2	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.8	2.3	GO:0002661	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.7	2.1	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.6	1.9	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.6	3.0	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.5	3.8	GO:0031642	negative regulation of myelination(GO:0031642)
0.5	1.4	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.4	1.3	GO:0070318	myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.4	4.5	GO:0002934	desmosome organization(GO:0002934)
0.4	2.9	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.3	1.0	GO:0010652	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.3	1.9	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3	0.9	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3	1.9	GO:2000391	positive regulation of neutrophil extravasation(GO:2000391)
0.3	1.5	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.3	1.5	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3	2.9	GO:0051552	flavone metabolic process(GO:0051552)
0.3	1.1	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.3	0.8	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.3	1.4	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.3	0.8	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	1.5	GO:0015820	leucine transport(GO:0015820)
0.2	4.9	GO:0001765	membrane raft assembly(GO:0001765)
0.2	1.2	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2	0.7	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2	0.7	GO:2000282	regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2	3.4	GO:0051546	keratinocyte migration(GO:0051546)
0.2	1.4	GO:0007296	vitellogenesis(GO:0007296)
0.2	0.5	GO:0060067	cervix development(GO:0060067)
0.2	0.7	GO:2000521	negative regulation of immunological synapse formation(GO:2000521)
0.2	1.1	GO:0003350	pulmonary myocardium development(GO:0003350)
0.2	0.2	GO:0031960	response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.2	1.0	GO:0071873	response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.2	1.2	GO:0072719	cellular response to cisplatin(GO:0072719)
0.2	1.3	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.2	2.6	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2	0.7	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.2	3.1	GO:0032060	bleb assembly(GO:0032060)
0.2	4.4	GO:0071294	cellular response to zinc ion(GO:0071294)
0.2	0.5	GO:0046521	sphingoid catabolic process(GO:0046521)
0.2	0.9	GO:0018158	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) protein oxidation(GO:0018158)
0.2	1.9	GO:0030322	stabilization of membrane potential(GO:0030322)
0.2	0.7	GO:0071461	cellular response to redox state(GO:0071461)
0.2	0.7	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.2	0.3	GO:0030220	platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.2	0.5	GO:0070638	nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.2	1.1	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2	0.8	GO:0015722	canalicular bile acid transport(GO:0015722)
0.2	0.5	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.2	4.7	GO:0007398	ectoderm development(GO:0007398)
0.2	0.5	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	3.2	GO:0003334	keratinocyte development(GO:0003334)
0.1	1.7	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	0.7	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1	1.0	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.1	0.8	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	3.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.1	0.5	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.1	1.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.4	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	0.5	GO:1900533	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1	0.4	GO:0009407	toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1	0.9	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1	0.4	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1	0.4	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.1	1.2	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.1	0.6	GO:0033383	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1	0.3	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	1.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.5	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.1	0.7	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	0.4	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1	0.7	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1	0.1	GO:0061055	myotome development(GO:0061055)
0.1	2.2	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.1	0.3	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.2	GO:2000320	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1	0.3	GO:1903028	positive regulation of opsonization(GO:1903028)
0.1	10.2	GO:0070268	cornification(GO:0070268)
0.1	0.4	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.1	0.5	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	4.9	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.2	GO:0035640	exploration behavior(GO:0035640) locomotory exploration behavior(GO:0035641)
0.1	6.2	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.5	GO:0015840	urea transport(GO:0015840)
0.1	0.6	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	2.5	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	0.4	GO:0044860	protein localization to plasma membrane raft(GO:0044860) protein transport into plasma membrane raft(GO:0044861)
0.1	1.5	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.8	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1	0.4	GO:0046502	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.4	GO:0043473	pigmentation(GO:0043473)
0.1	0.8	GO:0031346	positive regulation of cell projection organization(GO:0031346)
0.1	1.1	GO:0046415	urate metabolic process(GO:0046415)
0.1	0.5	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.6	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1	0.4	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1	0.2	GO:0060381	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
0.1	1.5	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	0.6	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.3	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1	0.3	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.1	1.4	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1	0.3	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1	1.1	GO:0016540	protein autoprocessing(GO:0016540)
0.1	0.6	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1	0.2	GO:0097264	self proteolysis(GO:0097264)
0.1	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	0.7	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.1	1.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	0.2	GO:0034334	adherens junction maintenance(GO:0034334)
0.1	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	0.2	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1	0.4	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.1	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.1	0.3	GO:0014718	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1	3.2	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.5	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.1	0.2	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.1	0.2	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.3	GO:0002084	protein depalmitoylation(GO:0002084)
0.1	0.5	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.1	0.4	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	0.2	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1	0.7	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.1	0.6	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.3	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.3	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:0048295	positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0	0.7	GO:0060347	heart trabecula formation(GO:0060347)
0.0	0.2	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	2.6	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.0	0.2	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.5	GO:0003373	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.1	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0010975	regulation of neuron projection development(GO:0010975)
0.0	0.1	GO:1990523	bone regeneration(GO:1990523)
0.0	0.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.1	GO:1905224	clathrin-coated pit assembly(GO:1905224)
0.0	0.1	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.0	0.1	GO:1900368	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.0	0.4	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
0.0	0.2	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.6	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.2	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.4	GO:1902172	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0	0.1	GO:1903236	regulation of leukocyte tethering or rolling(GO:1903236) positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0	0.2	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	0.5	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.3	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.2	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.2	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0071105	response to interleukin-11(GO:0071105)
0.0	0.4	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.3	GO:0019835	cytolysis(GO:0019835)
0.0	0.1	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.3	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.9	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.2	GO:0016128	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.0	0.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) retinal cell programmed cell death(GO:0046666)
0.0	0.1	GO:0007619	courtship behavior(GO:0007619)
0.0	0.2	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.4	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.3	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.1	GO:0034698	response to gonadotropin(GO:0034698)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.3	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.5	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.3	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.4	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0	0.2	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.0	2.6	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.3	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:1904578	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0	0.1	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0	0.4	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0	0.1	GO:0042361	menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0	0.3	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.0	0.2	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:1901318	negative regulation of sperm motility(GO:1901318)
0.0	0.2	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.2	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.0	0.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.2	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.1	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.3	GO:0051014	actin filament severing(GO:0051014)
0.0	0.4	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.1	GO:0032416	negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0	0.3	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.0	0.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.6	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.8	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.6	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	2.1	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.1	GO:1904429	regulation of t-circle formation(GO:1904429)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.2	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0	0.2	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.1	GO:0071724	toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0	0.1	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.0	0.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.0	0.8	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.1	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0	0.0	GO:0009726	detection of endogenous stimulus(GO:0009726)
0.0	0.1	GO:0048793	pronephros development(GO:0048793)
0.0	0.3	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	2.8	GO:0016573	histone acetylation(GO:0016573)
0.0	0.8	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.2	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.0	GO:0021987	cerebral cortex development(GO:0021987)
0.0	0.2	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	1.1	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.0	GO:0003095	pressure natriuresis(GO:0003095)
0.0	0.4	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.2	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.0	GO:0033341	regulation of collagen binding(GO:0033341)
0.0	0.0	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.1	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.1	GO:0001764	neuron migration(GO:0001764)
0.0	0.1	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.0	0.4	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0019732	antifungal humoral response(GO:0019732)
0.0	0.1	GO:1905229	thyroid-stimulating hormone signaling pathway(GO:0038194) cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:2001189	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.0	0.3	GO:0006469	negative regulation of protein kinase activity(GO:0006469) negative regulation of kinase activity(GO:0033673) negative regulation of transferase activity(GO:0051348)
0.0	0.1	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.0	GO:0001575	globoside metabolic process(GO:0001575)
0.0	0.4	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.0	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.4	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.5	GO:0070206	protein trimerization(GO:0070206)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.0	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.0	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	1.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.0	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.1	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	0.3	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.0	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.4	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	7.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	6.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	2.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	10.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	1.5	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.9	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	0.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	3.5	PID RAS PATHWAY	Regulation of Ras family activation
0.1	3.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.3	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	1.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.9	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	3.4	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	2.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.4	PID INSULIN PATHWAY	Insulin Pathway
0.0	1.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	1.3	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.9	PID BMP PATHWAY	BMP receptor signaling
0.0	0.7	PID ATM PATHWAY	ATM pathway
0.0	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.6	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.6	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	2.5	GO:0000145	exocyst(GO:0000145)
0.1	0.2	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	1.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.6	GO:0005955	calcineurin complex(GO:0005955)
0.1	1.4	GO:0000242	pericentriolar material(GO:0000242)
0.0	1.5	GO:0030673	axolemma(GO:0030673)
0.0	0.8	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	1.1	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	1.3	GO:0017053	transcriptional repressor complex(GO:0017053)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	6.4	GO:1990584	cardiac Troponin complex(GO:1990584)
0.4	3.9	GO:0071953	elastic fiber(GO:0071953)
0.4	6.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.3	3.0	GO:0071438	invadopodium membrane(GO:0071438)
0.2	7.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	0.7	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2	7.8	GO:0005859	muscle myosin complex(GO:0005859)
0.2	1.5	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	2.1	GO:0031932	TORC2 complex(GO:0031932)
0.1	2.1	GO:0032433	filopodium tip(GO:0032433)
0.1	1.0	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	0.3	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	0.5	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	1.6	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	1.4	GO:0030056	hemidesmosome(GO:0030056)
0.1	1.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	1.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	0.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	13.8	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.5	GO:0043218	compact myelin(GO:0043218)
0.0	4.5	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.7	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0005602	complement component C1 complex(GO:0005602)
0.0	0.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.6	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	2.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	2.3	GO:0005811	lipid particle(GO:0005811)
0.0	1.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	1.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.2	GO:0032059	bleb(GO:0032059)
0.0	0.4	GO:0031672	A band(GO:0031672)
0.0	3.2	GO:0030018	Z disc(GO:0030018)
0.0	0.4	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.3	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.8	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	1.3	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.6	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.7	GO:0005605	basal lamina(GO:0005605)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.7	GO:0045178	basal part of cell(GO:0045178)
0.0	5.8	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.7	GO:0005795	Golgi stack(GO:0005795)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	5.9	GO:0005925	focal adhesion(GO:0005925)
0.0	0.5	GO:0031904	endosome lumen(GO:0031904)
0.0	0.5	GO:0031526	brush border membrane(GO:0031526)
0.0	1.4	GO:0031901	early endosome membrane(GO:0031901)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.7	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	1.0	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.0	NABA COLLAGENS	Genes encoding collagen proteins
0.1	12.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	4.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	11.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.1	2.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	2.8	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	3.8	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	4.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	1.6	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	0.9	PID EPO PATHWAY	EPO signaling pathway
0.0	1.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	9.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.8	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	2.7	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	3.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	4.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	0.9	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	7.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.8	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	1.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	2.4	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.5	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	2.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.4	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
0.8	2.3	GO:0097447	dendritic tree(GO:0097447)
0.8	2.3	GO:0005873	plus-end kinesin complex(GO:0005873)
0.7	2.8	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.6	3.3	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.5	2.1	GO:1990423	RZZ complex(GO:1990423)
0.5	1.5	GO:0044393	microspike(GO:0044393)
0.5	1.9	GO:0000799	nuclear condensin complex(GO:0000799)
0.5	1.9	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.4	3.8	GO:0031298	replication fork protection complex(GO:0031298)
0.4	3.7	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.4	1.2	GO:0098536	deuterosome(GO:0098536)
0.4	1.2	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4	3.9	GO:0005828	kinetochore microtubule(GO:0005828)
0.4	1.1	GO:0031523	Myb complex(GO:0031523)
0.3	2.4	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.3	1.0	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.3	1.0	GO:0031262	Ndc80 complex(GO:0031262)
0.3	1.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3	2.0	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3	2.0	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.3	1.1	GO:0005846	nuclear cap binding complex(GO:0005846)
0.3	3.6	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.3	1.9	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2	2.5	GO:0070187	telosome(GO:0070187)
0.2	0.7	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.2	0.7	GO:0031213	RSF complex(GO:0031213)
0.2	1.9	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.2	0.7	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.2	0.9	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.2	1.7	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.2	0.8	GO:0033186	CAF-1 complex(GO:0033186)
0.2	6.7	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	1.4	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2	0.6	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.2	1.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.2	0.7	GO:0044611	nuclear pore inner ring(GO:0044611)
0.2	1.3	GO:0005663	DNA replication factor C complex(GO:0005663)
0.2	1.4	GO:0000322	storage vacuole(GO:0000322)
0.2	1.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.2	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2	1.5	GO:0070652	HAUS complex(GO:0070652)
0.2	2.0	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.2	0.6	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	0.6	GO:0043293	apoptosome(GO:0043293)
0.2	0.5	GO:0001652	granular component(GO:0001652)
0.2	1.7	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.2	1.1	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.4	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1	1.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.5	GO:0042025	host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1	1.1	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.2	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1	1.8	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	1.8	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.6	GO:0032021	NELF complex(GO:0032021)
0.1	0.4	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	0.5	GO:0033503	HULC complex(GO:0033503)
0.1	8.4	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	1.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	5.5	GO:0000786	nucleosome(GO:0000786)
0.1	2.6	GO:0000178	exosome (RNase complex)(GO:0000178)
0.1	1.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.7	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	2.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	0.4	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	1.6	GO:0034709	methylosome(GO:0034709)
0.1	0.4	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	1.7	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	1.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	0.2	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	0.4	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	1.4	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.1	0.4	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	2.2	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	2.2	GO:0035371	microtubule plus-end(GO:0035371)
0.1	1.5	GO:0097440	apical dendrite(GO:0097440)
0.1	0.3	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.1	0.6	GO:0042382	paraspeckles(GO:0042382)
0.1	2.7	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	0.2	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	0.3	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.1	0.3	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	2.5	GO:0005876	spindle microtubule(GO:0005876)
0.1	0.4	GO:0030681	multimeric ribonuclease P complex(GO:0030681)
0.1	0.6	GO:0000439	core TFIIH complex(GO:0000439)
0.1	1.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.3	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.1	0.9	GO:0032156	septin cytoskeleton(GO:0032156)
0.1	0.2	GO:0031085	BLOC-3 complex(GO:0031085)
0.1	1.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.3	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.3	GO:0030893	meiotic cohesin complex(GO:0030893)
0.1	0.5	GO:0070552	BRISC complex(GO:0070552)
0.1	0.2	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1	3.6	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.1	1.5	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1	0.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.1	0.5	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.7	GO:0030686	90S preribosome(GO:0030686)
0.1	0.2	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.0	0.1	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.3	GO:0072487	MSL complex(GO:0072487)
0.0	0.5	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.6	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	2.1	GO:0043034	costamere(GO:0043034)
0.0	4.9	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	2.2	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	3.4	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.3	GO:0031415	NatA complex(GO:0031415)
0.0	0.4	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.8	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	2.1	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.7	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0098839	postsynaptic density membrane(GO:0098839)
0.0	0.5	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.1	GO:0070419	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) nonhomologous end joining complex(GO:0070419)
0.0	0.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.6	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	2.7	GO:0014704	intercalated disc(GO:0014704)
0.0	0.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.5	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.7	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	13.2	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.4	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	1.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.5	GO:0035102	PRC1 complex(GO:0035102)
0.0	3.9	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.0	0.3	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.5	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	1.6	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.2	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.6	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.7	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	1.2	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.2	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.3	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.3	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.4	GO:0032433	filopodium tip(GO:0032433)
0.0	0.1	GO:0019867	outer membrane(GO:0019867)
0.0	0.1	GO:0033011	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.3	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	1.9	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	6.5	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	1.9	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	1.8	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.4	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.0	0.2	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.6	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0	0.2	GO:0098552	side of membrane(GO:0098552)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.6	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.5	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.4	GO:0016235	aggresome(GO:0016235)
0.0	1.2	GO:0008021	synaptic vesicle(GO:0008021)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.4	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0	0.5	GO:0043198	dendritic shaft(GO:0043198)
0.0	1.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.4	GO:0032982	myosin filament(GO:0032982)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.4	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.5	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.0	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	1.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.2	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	1.4	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	1.1	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.1	GO:0031906	late endosome lumen(GO:0031906)
0.0	0.4	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	0.8	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.7	2.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.5	0.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.4	9.8	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	8.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.3	17.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.3	1.5	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.3	3.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.3	1.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.2	4.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	1.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.2	10.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2	12.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	9.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	9.0	PID IL2 1PATHWAY	IL2-mediated signaling events
0.2	3.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2	8.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	5.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	13.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	6.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.2	7.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	3.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	5.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	2.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	2.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	13.0	PID NOTCH PATHWAY	Notch signaling pathway
0.2	1.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2	7.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	1.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.2	5.1	PID MYC PATHWAY	C-MYC pathway
0.2	5.3	PID RAS PATHWAY	Regulation of Ras family activation
0.2	3.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	5.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	5.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	2.9	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	2.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	2.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	3.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	3.3	PID AURORA A PATHWAY	Aurora A signaling
0.1	1.6	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	2.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	6.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	3.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	4.4	PID ATR PATHWAY	ATR signaling pathway
0.1	1.0	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	0.9	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	1.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	1.6	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	1.9	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	6.0	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.1	0.9	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	1.5	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.1	7.8	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	0.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	2.4	PID P73PATHWAY	p73 transcription factor network
0.1	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	0.9	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	1.5	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	0.6	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	0.9	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.1	1.5	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	1.9	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	1.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	0.8	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.2	PID ARF 3PATHWAY	Arf1 pathway
0.1	5.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	1.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.9	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	0.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	3.1	PID AURORA B PATHWAY	Aurora B signaling
0.1	1.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	1.4	PID BARD1 PATHWAY	BARD1 signaling events
0.1	4.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	1.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.3	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.2	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.6	PID ATM PATHWAY	ATM pathway
0.0	0.9	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	1.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.9	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	1.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.4	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.6	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.8	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	1.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.4	PID BMP PATHWAY	BMP receptor signaling
0.0	1.5	PID E2F PATHWAY	E2F transcription factor network
0.0	1.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.6	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	1.0	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.0	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0046102	hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102)
0.6	1.8	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.6	1.8	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.6	2.8	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.5	1.5	GO:1902771	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.5	2.1	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.5	3.5	GO:0070269	pyroptosis(GO:0070269)
0.4	2.2	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.4	2.1	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
0.4	1.7	GO:0071461	cellular response to redox state(GO:0071461)
0.4	1.2	GO:0045062	extrathymic T cell selection(GO:0045062)
0.4	2.4	GO:0016554	cytidine to uridine editing(GO:0016554)
0.4	1.2	GO:0070340	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.4	1.2	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.3	0.9	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.3	1.2	GO:0046967	cytosol to ER transport(GO:0046967)
0.3	1.8	GO:0036337	Fas signaling pathway(GO:0036337)
0.3	2.1	GO:0044351	macropinocytosis(GO:0044351)
0.3	1.5	GO:0032252	secretory granule localization(GO:0032252)
0.2	2.2	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2	0.7	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2	0.7	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.2	0.9	GO:0072183	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.2	0.4	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2	0.2	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) negative regulation of response to DNA damage stimulus(GO:2001021)
0.2	0.7	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.2	0.5	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2	0.5	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1	0.9	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.4	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	1.5	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.1	0.4	GO:0061461	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1	1.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	0.4	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.1	0.5	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.5	GO:0015808	L-alanine transport(GO:0015808)
0.1	0.5	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.1	0.4	GO:2001191	gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1	0.7	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.1	0.8	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.7	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	0.3	GO:0072709	cellular response to sorbitol(GO:0072709)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.3	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	0.3	GO:0002352	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1	0.3	GO:1990641	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1	0.5	GO:0014738	regulation of muscle hyperplasia(GO:0014738)
0.1	0.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1	1.8	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.3	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.1	0.1	GO:0030856	regulation of epithelial cell differentiation(GO:0030856)
0.1	0.7	GO:1903232	melanosome assembly(GO:1903232)
0.1	4.7	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.6	GO:0018377	protein myristoylation(GO:0018377)
0.1	0.5	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1	0.3	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.1	0.3	GO:2000538	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1	0.1	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.1	1.4	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	0.2	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1	0.4	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1	0.6	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1	0.2	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.1	0.3	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	9.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.1	1.1	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1	0.7	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.1	0.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.1	GO:0002027	regulation of heart rate(GO:0002027)
0.1	0.5	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.6	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.1	0.3	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1	0.2	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.1	0.6	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	1.3	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.2	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.9	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.1	0.5	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	0.5	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	0.5	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.1	0.2	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	1.2	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.1	0.2	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1	0.4	GO:0045807	positive regulation of endocytosis(GO:0045807)
0.1	0.4	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	0.2	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1	0.2	GO:0002125	maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.1	1.5	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.2	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.1	1.5	GO:0016601	Rac protein signal transduction(GO:0016601)
0.1	0.5	GO:0051026	chiasma assembly(GO:0051026)
0.1	0.3	GO:0072141	renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.1	0.4	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1	1.0	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.1	0.5	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.2	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0	0.1	GO:0070632	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0	0.1	GO:0046080	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0	0.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.3	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	0.1	GO:0002436	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.0	0.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0002767	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.2	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0	0.2	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.0	1.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.2	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0	0.4	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.2	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.0	0.3	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0090024	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0	0.3	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.4	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.1	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.1	GO:0003335	corneocyte development(GO:0003335)
0.0	0.5	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.1	GO:1902994	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.0	0.1	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0	0.3	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0097254	renal tubular secretion(GO:0097254)
0.0	0.4	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.4	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.3	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0061528	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0	0.8	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	1.2	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.1	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.0	0.7	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.8	GO:0045730	respiratory burst(GO:0045730)
0.0	0.3	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.3	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0	0.3	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.4	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	1.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.5	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.2	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0	0.3	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.2	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.2	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.1	GO:0019556	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0	0.3	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0	0.3	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.3	GO:0006612	protein targeting to membrane(GO:0006612)
0.0	0.1	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.0	0.0	GO:1904252	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252) regulation of forebrain neuron differentiation(GO:2000977)
0.0	0.3	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.2	GO:1903358	regulation of Golgi organization(GO:1903358)
0.0	0.2	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.6	GO:0097503	sialylation(GO:0097503)
0.0	0.1	GO:0009386	translational attenuation(GO:0009386)
0.0	0.1	GO:0031126	snoRNA 3'-end processing(GO:0031126)
0.0	0.2	GO:0008218	bioluminescence(GO:0008218)
0.0	0.4	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.5	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.8	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0052422	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:1904482	response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0	0.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.1	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0	1.5	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.7	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.5	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.3	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.1	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.1	GO:1904597	regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.0	2.8	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0	0.4	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.0	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.3	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.5	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.2	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.0	GO:0042369	vitamin D catabolic process(GO:0042369)
0.0	0.0	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.0	0.5	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.4	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0071109	superior temporal gyrus development(GO:0071109)
0.0	0.1	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0	1.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.7	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.1	GO:0060068	vagina development(GO:0060068)
0.0	0.0	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.0	0.1	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.3	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.7	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.1	GO:0071442	regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.3	GO:0044030	regulation of DNA methylation(GO:0044030)
0.0	0.0	GO:1901053	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0	0.8	GO:0002250	adaptive immune response(GO:0002250)
0.0	1.5	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.8	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.1	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.1	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0	0.1	GO:1901538	DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.6	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0	0.0	GO:0016240	autophagosome docking(GO:0016240)
0.0	0.1	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.5	GO:0043687	post-translational protein modification(GO:0043687)
0.0	0.6	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.0	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
0.0	0.5	GO:0046427	positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.6	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.0	GO:0097178	ruffle assembly(GO:0097178)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	1.2	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.3	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.0	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:1990922	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4	1.6	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3	0.9	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.3	0.6	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.2	0.6	GO:0007518	myoblast fate determination(GO:0007518)
0.2	0.5	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1	0.6	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	0.4	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1	0.4	GO:0006550	isoleucine catabolic process(GO:0006550)
0.1	0.7	GO:0071233	cellular response to leucine(GO:0071233)
0.1	0.4	GO:0006549	isoleucine metabolic process(GO:0006549)
0.1	0.7	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.1	0.4	GO:1902661	positive regulation of glucose mediated signaling pathway(GO:1902661)
0.1	0.4	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	0.8	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.1	0.6	GO:0032252	secretory granule localization(GO:0032252)
0.1	0.4	GO:0008063	Toll signaling pathway(GO:0008063)
0.1	0.3	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1	0.3	GO:0043060	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1	0.4	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.3	GO:1990868	response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1	0.5	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	0.2	GO:0036071	N-glycan fucosylation(GO:0036071)
0.1	0.2	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.1	0.5	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.9	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.5	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.1	0.2	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	0.5	GO:0035624	receptor transactivation(GO:0035624)
0.1	0.2	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1	0.2	GO:0060178	regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.1	0.2	GO:0045976	negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1	0.4	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	1.0	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	0.2	GO:0009224	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.5	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.2	GO:1903973	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1	0.3	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.1	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.1	0.2	GO:0007412	axon target recognition(GO:0007412)
0.1	0.2	GO:1904617	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1	0.2	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.1	0.2	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1	0.2	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0	0.2	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.2	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.5	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.5	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.2	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.1	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.0	0.1	GO:1902822	cleavage furrow ingression(GO:0036090) regulation of late endosome to lysosome transport(GO:1902822)
0.0	0.5	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0	0.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.2	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0	0.1	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.3	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.0	0.2	GO:1990164	histone H2A phosphorylation(GO:1990164)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.0	0.2	GO:0009450	gamma-aminobutyric acid catabolic process(GO:0009450)
0.0	0.1	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.1	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.2	GO:1901628	positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911)
0.0	1.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0	0.1	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0	0.1	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.1	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0	0.2	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.0	0.4	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.2	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.1	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.0	0.4	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.6	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0071072	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.2	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.2	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.1	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.3	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:2000987	positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0	0.5	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.0	0.1	GO:0061056	sclerotome development(GO:0061056)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.3	GO:0051451	myoblast migration(GO:0051451)
0.0	0.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.1	GO:0061081	positive regulation of macrophage cytokine production(GO:0060907) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.1	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0	0.1	GO:0061074	regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0	0.1	GO:0015743	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0019230	proprioception(GO:0019230)
0.0	0.2	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	0.1	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0	0.1	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.3	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.1	GO:1902965	terminal web assembly(GO:1902896) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.1	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.1	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0050915	sensory perception of sour taste(GO:0050915)
0.0	0.1	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.2	GO:0032341	aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342)
0.0	0.5	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.1	GO:0032072	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.5	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.2	GO:0000012	single strand break repair(GO:0000012)
0.0	0.3	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.2	GO:0071313	cellular response to caffeine(GO:0071313)
0.0	0.1	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.2	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.0	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.1	GO:0071630	nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0	0.1	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.1	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	0.0	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0032687	negative regulation of interferon-alpha production(GO:0032687) regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0	0.2	GO:0032310	prostaglandin secretion(GO:0032310)
0.0	0.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.0	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.0	0.4	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.1	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.1	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.0	0.0	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.0	0.7	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.3	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0	0.1	GO:0072396	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0	0.1	GO:0019086	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0	0.3	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.2	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	0.0	GO:0072054	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.0	GO:0021558	trochlear nerve development(GO:0021558)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0060149	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) negative regulation of gene silencing(GO:0060969)
0.0	0.6	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0060897	neural plate regionalization(GO:0060897)
0.0	0.2	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.4	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:1904690	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0	0.0	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.0	0.0	GO:0043974	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0	0.1	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.2	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0015824	proline transport(GO:0015824)
0.0	0.1	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.0	GO:0042247	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0	0.1	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.1	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.2	GO:0072348	sulfur compound transport(GO:0072348)
0.0	0.0	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.5	GO:0070911	global genome nucleotide-excision repair(GO:0070911)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.7	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
2.1	8.3	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
1.8	5.5	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
1.8	5.4	GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.7	6.9	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
1.7	8.5	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.5	4.6	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.4	1.4	GO:0006624	vacuolar protein processing(GO:0006624)
1.3	3.9	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.2	3.5	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
1.2	3.5	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
1.2	4.6	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
1.1	4.4	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
1.1	5.4	GO:0048478	replication fork protection(GO:0048478)
1.1	3.2	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
1.1	4.3	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
1.1	6.3	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
1.0	4.1	GO:0046452	dihydrofolate metabolic process(GO:0046452)
1.0	4.9	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.0	6.7	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
1.0	3.8	GO:0006542	glutamine biosynthetic process(GO:0006542)
1.0	2.9	GO:2000653	regulation of genetic imprinting(GO:2000653)
1.0	2.9	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
1.0	7.6	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.9	2.8	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.9	0.9	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.9	3.7	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.9	3.5	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.9	1.8	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.9	2.6	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.9	3.4	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.9	2.6	GO:1903939	regulation of TORC2 signaling(GO:1903939)
0.8	2.5	GO:0060152	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.8	5.0	GO:0016074	snoRNA metabolic process(GO:0016074)
0.8	0.8	GO:0072711	cellular response to hydroxyurea(GO:0072711)
0.8	2.5	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.8	2.4	GO:1902019	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.8	0.8	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.8	6.3	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.8	2.3	GO:0019858	cytosine metabolic process(GO:0019858)
0.8	2.3	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
0.7	4.5	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.7	0.7	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.7	2.2	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.7	3.7	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.7	2.9	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.7	2.2	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.7	30.8	GO:0006270	DNA replication initiation(GO:0006270)
0.7	2.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.7	5.6	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.7	2.1	GO:1901656	glycoside transport(GO:1901656)
0.7	2.1	GO:0070512	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.7	11.8	GO:0006265	DNA topological change(GO:0006265)
0.7	2.1	GO:0015920	lipopolysaccharide transport(GO:0015920)
0.7	2.1	GO:0000967	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.7	2.7	GO:0006203	dGTP catabolic process(GO:0006203)
0.7	2.7	GO:0006408	snRNA export from nucleus(GO:0006408)
0.7	2.0	GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.7	0.7	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.7	2.0	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.7	0.7	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.7	2.0	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.7	1.3	GO:0097327	response to antineoplastic agent(GO:0097327)
0.7	10.5	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7	5.3	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.7	3.3	GO:0016240	autophagosome docking(GO:0016240)
0.7	4.6	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.6	3.2	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.6	7.0	GO:0000478	endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.6	3.8	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.6	5.7	GO:1901977	negative regulation of cell cycle checkpoint(GO:1901977)
0.6	25.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.6	2.5	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.6	4.9	GO:0032790	ribosome disassembly(GO:0032790)
0.6	1.8	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.6	4.2	GO:0010041	response to iron(III) ion(GO:0010041)
0.6	2.3	GO:0032218	riboflavin transport(GO:0032218)
0.6	2.9	GO:0072301	regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.6	0.6	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.6	9.9	GO:0006020	inositol metabolic process(GO:0006020)
0.6	5.8	GO:1904869	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.6	2.3	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.6	3.5	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.6	1.7	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.6	2.3	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.6	1.7	GO:1904751	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.6	4.0	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.6	3.4	GO:0030421	defecation(GO:0030421)
0.6	3.3	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.6	1.7	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.5	3.3	GO:0051013	microtubule severing(GO:0051013)
0.5	1.6	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.5	2.2	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.5	2.7	GO:0046203	spermidine catabolic process(GO:0046203)
0.5	7.5	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.5	1.6	GO:0036090	cleavage furrow ingression(GO:0036090)
0.5	2.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.5	1.6	GO:0051685	maintenance of ER location(GO:0051685)
0.5	1.6	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.5	0.5	GO:0040031	snRNA modification(GO:0040031)
0.5	2.6	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.5	7.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5	1.6	GO:0006550	isoleucine catabolic process(GO:0006550)
0.5	1.6	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.5	0.5	GO:2000232	regulation of rRNA processing(GO:2000232)
0.5	2.0	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.5	1.5	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.5	4.6	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.5	1.0	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.5	0.5	GO:0009106	lipoate metabolic process(GO:0009106)
0.5	1.5	GO:0034227	tRNA thio-modification(GO:0034227)
0.5	1.5	GO:1902528	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.5	2.0	GO:0034445	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.5	0.5	GO:0090183	regulation of kidney development(GO:0090183)
0.5	4.9	GO:0043249	erythrocyte maturation(GO:0043249)
0.5	5.4	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.5	5.8	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.5	0.5	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.5	1.9	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.5	5.8	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.5	4.8	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.5	1.9	GO:0071492	cellular response to UV-A(GO:0071492)
0.5	6.2	GO:0045008	depyrimidination(GO:0045008)
0.5	20.4	GO:0051031	tRNA transport(GO:0051031)
0.5	3.8	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.5	7.6	GO:0016180	snRNA processing(GO:0016180)
0.5	34.4	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.5	0.5	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.5	4.7	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5	1.9	GO:0006338	chromatin remodeling(GO:0006338)
0.5	5.1	GO:1904872	regulation of telomerase RNA localization to Cajal body(GO:1904872)
0.5	2.3	GO:0007068	negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.5	0.9	GO:1902724	positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.4	1.3	GO:0070668	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.4	1.3	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4	1.8	GO:0019249	lactate biosynthetic process(GO:0019249)
0.4	1.8	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
0.4	2.2	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.4	1.8	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.4	0.9	GO:0043096	purine nucleobase salvage(GO:0043096)
0.4	2.2	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.4	3.0	GO:0006102	isocitrate metabolic process(GO:0006102)
0.4	1.7	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.4	6.2	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.4	4.1	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.4	1.2	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
0.4	0.4	GO:0036480	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
0.4	6.5	GO:0043248	proteasome assembly(GO:0043248)
0.4	1.2	GO:1902567	negative regulation of eosinophil activation(GO:1902567) negative regulation of eosinophil migration(GO:2000417)
0.4	4.8	GO:0006108	malate metabolic process(GO:0006108)
0.4	4.8	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.4	1.6	GO:0042278	purine nucleoside metabolic process(GO:0042278)
0.4	3.5	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.4	4.3	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.4	2.0	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.4	1.2	GO:0046081	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.4	1.9	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4	1.5	GO:0032053	ciliary basal body organization(GO:0032053)
0.4	1.1	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.4	1.5	GO:0008053	mitochondrial fusion(GO:0008053)
0.4	1.1	GO:0009304	tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.4	3.1	GO:0016926	protein desumoylation(GO:0016926)
0.4	0.7	GO:1902570	protein localization to nucleolus(GO:1902570)
0.4	1.1	GO:0060352	cell adhesion molecule production(GO:0060352)
0.4	2.2	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.4	1.9	GO:0051650	establishment of vesicle localization(GO:0051650)
0.4	1.5	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.4	2.2	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4	1.1	GO:0046449	creatinine metabolic process(GO:0046449)
0.4	1.1	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.4	1.1	GO:0090670	RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672)
0.4	1.1	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4	1.1	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.4	2.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4	3.2	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.4	1.1	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3	1.7	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.3	0.7	GO:0071314	cellular response to cocaine(GO:0071314)
0.3	4.8	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.3	0.3	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.3	1.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	9.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.3	0.7	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.3	2.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.3	0.7	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.3	1.0	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.3	0.7	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.3	1.3	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296)
0.3	1.6	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3	3.6	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3	2.3	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.3	1.0	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.3	1.0	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.3	8.0	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3	2.2	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.3	1.0	GO:0048075	positive regulation of eye pigmentation(GO:0048075)
0.3	18.8	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.3	3.5	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.3	0.9	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.3	0.6	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.3	0.6	GO:0006740	NADPH regeneration(GO:0006740)
0.3	0.9	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3	1.6	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.3	2.8	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.3	1.6	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.3	0.6	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.3	4.9	GO:0043486	histone exchange(GO:0043486)
0.3	0.6	GO:0070200	establishment of protein localization to telomere(GO:0070200)
0.3	1.5	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.3	0.6	GO:0033750	ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.3	0.3	GO:0010993	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.3	1.5	GO:1901093	regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.3	5.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.3	1.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.3	1.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3	1.5	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.3	0.6	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.3	0.6	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.3	0.9	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.3	0.9	GO:1901355	response to rapamycin(GO:1901355)
0.3	7.7	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.3	1.2	GO:1903935	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.3	0.6	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.3	6.2	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3	0.9	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.3	0.9	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3	0.6	GO:0001522	pseudouridine synthesis(GO:0001522)
0.3	1.1	GO:0019086	late viral transcription(GO:0019086)
0.3	4.6	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.3	0.9	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.3	0.3	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3	1.7	GO:0033504	floor plate development(GO:0033504)
0.3	0.3	GO:0035087	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.3	1.7	GO:0070827	chromatin maintenance(GO:0070827)
0.3	0.3	GO:0072237	metanephric proximal tubule development(GO:0072237)
0.3	0.3	GO:0070585	protein localization to mitochondrion(GO:0070585)
0.3	12.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.3	1.4	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.3	0.8	GO:0006172	ADP biosynthetic process(GO:0006172)
0.3	1.1	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.3	2.2	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.3	2.8	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3	0.3	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.3	0.5	GO:0006452	translational frameshifting(GO:0006452) peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.3	0.8	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.3	0.8	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3	9.0	GO:1902593	single-organism nuclear import(GO:1902593)
0.3	9.8	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.3	2.7	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.3	1.1	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.3	1.3	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.3	2.4	GO:0000732	strand displacement(GO:0000732)
0.3	1.1	GO:2000313	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3	1.1	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.3	0.3	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378) vitamin D3 metabolic process(GO:0070640)
0.3	1.8	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.3	0.8	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3	2.1	GO:0032025	response to cobalt ion(GO:0032025)
0.3	0.5	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.3	1.0	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.3	1.0	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.3	0.3	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.3	1.0	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.3	4.8	GO:0006400	tRNA modification(GO:0006400)
0.3	1.3	GO:0070092	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.3	0.5	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3	1.5	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.3	1.0	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.3	1.8	GO:0007144	female meiosis I(GO:0007144)
0.3	1.8	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.2	0.5	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.2	0.7	GO:0000012	single strand break repair(GO:0000012)
0.2	0.2	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.2	0.7	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.2	0.7	GO:0009826	unidimensional cell growth(GO:0009826)
0.2	2.5	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.2	2.2	GO:0072520	seminiferous tubule development(GO:0072520)
0.2	0.5	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2	0.7	GO:0070781	response to biotin(GO:0070781)
0.2	3.6	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2	0.7	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2	0.5	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.2	4.3	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.2	0.2	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.2	0.5	GO:0046070	dGTP metabolic process(GO:0046070)
0.2	1.2	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.2	0.5	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.2	1.9	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.2	8.9	GO:0001510	RNA methylation(GO:0001510)
0.2	3.0	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.2	0.7	GO:0006566	threonine metabolic process(GO:0006566)
0.2	0.9	GO:0071895	odontoblast differentiation(GO:0071895)
0.2	0.5	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
0.2	1.4	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.2	4.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.2	1.6	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.2	1.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.2	3.8	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2	0.5	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.2	0.4	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.2	0.4	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.2	2.7	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.2	7.5	GO:0008033	tRNA processing(GO:0008033)
0.2	1.3	GO:0075713	establishment of integrated proviral latency(GO:0075713)
0.2	1.5	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.2	0.7	GO:0032679	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.2	0.9	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2	0.7	GO:0045116	protein neddylation(GO:0045116)
0.2	2.0	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2	0.4	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2	1.5	GO:2001169	regulation of ATP biosynthetic process(GO:2001169)
0.2	1.3	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.2	0.4	GO:0015729	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2	0.2	GO:1903507	negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)
0.2	5.8	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.2	2.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.2	0.2	GO:0036065	fucosylation(GO:0036065)
0.2	0.4	GO:0048339	paraxial mesoderm development(GO:0048339)
0.2	1.5	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.2	0.2	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.2	0.6	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.2	0.6	GO:0060897	neural plate regionalization(GO:0060897)
0.2	1.3	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2	0.8	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2	0.6	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.2	0.4	GO:0061010	gall bladder development(GO:0061010)
0.2	2.0	GO:0045059	positive thymic T cell selection(GO:0045059)
0.2	0.6	GO:0002084	protein depalmitoylation(GO:0002084)
0.2	0.4	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2	1.2	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2	0.2	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.2	1.6	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.2	0.6	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.2	0.4	GO:0051182	coenzyme transport(GO:0051182)
0.2	0.8	GO:0045350	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357)
0.2	0.6	GO:0032466	negative regulation of cytokinesis(GO:0032466)
0.2	2.2	GO:0015074	DNA integration(GO:0015074)
0.2	2.0	GO:0018065	protein-cofactor linkage(GO:0018065)
0.2	0.6	GO:2000768	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2	0.6	GO:0031133	regulation of axon diameter(GO:0031133)
0.2	1.5	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.2	0.2	GO:0043132	NAD transport(GO:0043132)
0.2	1.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.2	1.1	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2	1.3	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.2	0.6	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2	0.8	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
0.2	2.5	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.2	3.8	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.2	0.8	GO:1901984	negative regulation of protein acetylation(GO:1901984)
0.2	0.4	GO:0006106	fumarate metabolic process(GO:0006106)
0.2	0.6	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.2	1.9	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.2	0.9	GO:0051305	mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305)
0.2	1.5	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.2	0.4	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.2	4.6	GO:0051290	protein heterotetramerization(GO:0051290)
0.2	0.9	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.2	0.6	GO:1901998	toxin transport(GO:1901998)
0.2	1.5	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.2	1.3	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2	1.1	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	4.2	GO:0070897	DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.2	3.4	GO:0006337	nucleosome disassembly(GO:0006337)
0.2	0.9	GO:0071233	cellular response to leucine(GO:0071233)
0.2	0.4	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2	0.2	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.2	0.5	GO:0007051	spindle organization(GO:0007051)
0.2	0.2	GO:0021675	nerve development(GO:0021675)
0.2	0.2	GO:0072139	glomerular parietal epithelial cell differentiation(GO:0072139)
0.2	1.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.2	0.3	GO:0006538	glutamate catabolic process(GO:0006538)
0.2	1.0	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.2	2.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2	1.0	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.2	1.6	GO:0006983	ER overload response(GO:0006983)
0.2	0.3	GO:0035995	detection of muscle stretch(GO:0035995)
0.2	10.5	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2	1.7	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.2	1.2	GO:1902969	mitotic DNA replication(GO:1902969)
0.2	0.3	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.2	5.6	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.2	9.5	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.2	1.2	GO:0035799	ureter maturation(GO:0035799)
0.2	10.8	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.2	0.2	GO:0014070	response to organic cyclic compound(GO:0014070)
0.2	2.5	GO:0035855	megakaryocyte development(GO:0035855)
0.2	0.2	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.2	0.5	GO:0043418	homocysteine catabolic process(GO:0043418)
0.2	0.2	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.2	2.0	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2	0.3	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.2	0.3	GO:1904925	positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2	0.3	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
0.2	1.6	GO:0015886	heme transport(GO:0015886)
0.2	1.0	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2	0.6	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2	0.3	GO:0007113	endomitotic cell cycle(GO:0007113)
0.2	0.3	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.2	0.2	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.2	1.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.2	1.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.2	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.2	1.3	GO:0006105	succinate metabolic process(GO:0006105)
0.2	0.5	GO:0060061	Spemann organizer formation(GO:0060061)
0.2	0.6	GO:0014029	neural crest formation(GO:0014029)
0.2	5.3	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.2	0.3	GO:0033590	response to cobalamin(GO:0033590)
0.2	0.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2	0.6	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.2	1.2	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.2	0.5	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.2	0.9	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.2	1.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.2	0.6	GO:0060896	neural plate pattern specification(GO:0060896)
0.2	1.5	GO:0015889	cobalamin transport(GO:0015889)
0.2	0.2	GO:0031055	chromatin remodeling at centromere(GO:0031055)
0.2	0.8	GO:1902739	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1	1.2	GO:0015816	glycine transport(GO:0015816)
0.1	0.4	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1	1.2	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.1	0.7	GO:0000050	urea cycle(GO:0000050)
0.1	1.2	GO:0018022	peptidyl-lysine methylation(GO:0018022)
0.1	1.5	GO:0002115	store-operated calcium entry(GO:0002115)
0.1	0.4	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
0.1	0.7	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	0.9	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.4	GO:1904404	transcription factor catabolic process(GO:0036369) cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1	4.0	GO:0007091	metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
0.1	0.6	GO:0044539	long-chain fatty acid import(GO:0044539)
0.1	0.6	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	1.9	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.6	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1	0.1	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1	1.3	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1	0.9	GO:0006196	AMP catabolic process(GO:0006196)
0.1	0.1	GO:0060996	dendritic spine development(GO:0060996)
0.1	0.4	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.1	2.3	GO:0051181	cofactor transport(GO:0051181)
0.1	0.6	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1	5.4	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.1	1.9	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.1	14.4	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1	0.6	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.1	1.4	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	1.0	GO:0035898	parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1	0.7	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.7	GO:0042631	cellular response to water deprivation(GO:0042631)
0.1	3.2	GO:0030033	microvillus assembly(GO:0030033)
0.1	0.7	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	1.8	GO:0021670	lateral ventricle development(GO:0021670)
0.1	0.7	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.5	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	1.2	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1	0.7	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	2.4	GO:0051767	nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769)
0.1	0.5	GO:0021553	olfactory nerve development(GO:0021553)
0.1	0.5	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	5.4	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	1.1	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.1	0.8	GO:0006824	cobalt ion transport(GO:0006824)
0.1	0.3	GO:0042940	D-amino acid transport(GO:0042940)
0.1	0.7	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	1.1	GO:0001865	NK T cell differentiation(GO:0001865)
0.1	0.5	GO:0033029	neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031)
0.1	1.4	GO:0050655	dermatan sulfate proteoglycan biosynthetic process(GO:0050651) dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1	0.4	GO:0042351	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1	0.3	GO:0072718	response to cisplatin(GO:0072718)
0.1	0.8	GO:0015853	adenine transport(GO:0015853)
0.1	2.2	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1	0.8	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1	0.5	GO:0030242	pexophagy(GO:0030242)
0.1	2.7	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	2.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	0.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	1.3	GO:0035747	natural killer cell chemotaxis(GO:0035747)
0.1	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.1	1.2	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
0.1	0.5	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1	0.2	GO:0048550	negative regulation of pinocytosis(GO:0048550) regulation of secretion of lysosomal enzymes(GO:0090182)
0.1	0.2	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.5	GO:1904978	regulation of endosome organization(GO:1904978)
0.1	1.8	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.5	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1	0.2	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1	0.4	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	0.4	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1	1.3	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
0.1	1.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.5	GO:0046324	regulation of glucose import(GO:0046324)
0.1	1.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.4	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.6	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	1.4	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	3.5	GO:0035825	reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1	0.7	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.1	0.2	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.1	1.3	GO:0030157	pancreatic juice secretion(GO:0030157)
0.1	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.1	0.2	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.1	0.3	GO:0010957	negative regulation of vitamin D biosynthetic process(GO:0010957)
0.1	0.6	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.3	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1	0.7	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.5	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.6	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.1	0.6	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.1	1.8	GO:0016578	histone deubiquitination(GO:0016578)
0.1	1.9	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	0.1	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1	0.6	GO:1904526	regulation of microtubule binding(GO:1904526)
0.1	0.2	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.1	1.5	GO:0021924	cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1	0.2	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.1	0.4	GO:0006285	base-excision repair, AP site formation(GO:0006285) depurination(GO:0045007)
0.1	0.6	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.1	0.3	GO:0006868	glutamine transport(GO:0006868)
0.1	1.0	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.1	1.0	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.3	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1	0.2	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.1	0.1	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1	1.4	GO:0039694	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1	1.5	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	0.4	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.3	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.4	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.3	GO:0043255	regulation of polysaccharide biosynthetic process(GO:0032885) regulation of carbohydrate biosynthetic process(GO:0043255)
0.1	0.9	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.7	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1	0.3	GO:0002071	glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1	0.1	GO:0033206	meiotic cytokinesis(GO:0033206)
0.1	0.7	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.4	GO:0070813	hydrogen sulfide metabolic process(GO:0070813) hydrogen sulfide biosynthetic process(GO:0070814)
0.1	1.7	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.1	0.3	GO:0021571	rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.3	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	0.5	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.9	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.9	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.1	1.6	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	1.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	2.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.3	GO:0006625	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1	0.4	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.5	GO:0048619	embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.1	0.7	GO:0042262	DNA protection(GO:0042262)
0.1	0.6	GO:0048681	negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1	0.6	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	0.3	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.3	GO:0008355	olfactory learning(GO:0008355)
0.1	2.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.1	GO:0002159	desmosome assembly(GO:0002159)
0.1	0.5	GO:0009838	abscission(GO:0009838)
0.1	0.4	GO:0043488	regulation of RNA stability(GO:0043487) regulation of mRNA stability(GO:0043488)
0.1	0.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.5	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.3	GO:1902896	terminal web assembly(GO:1902896)
0.1	0.2	GO:0097156	fasciculation of motor neuron axon(GO:0097156)
0.1	1.9	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1	0.9	GO:0009303	rRNA transcription(GO:0009303)
0.1	0.6	GO:0042559	pteridine-containing compound biosynthetic process(GO:0042559)
0.1	0.2	GO:0019322	pentose biosynthetic process(GO:0019322)
0.1	0.4	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	1.7	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1	0.5	GO:0015862	uridine transport(GO:0015862)
0.1	0.2	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1	0.7	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.4	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.1	0.2	GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1	0.3	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.1	0.1	GO:0071971	extracellular exosome assembly(GO:0071971) regulation of extracellular exosome assembly(GO:1903551)
0.1	0.6	GO:0060017	parathyroid gland development(GO:0060017)
0.1	1.9	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.1	0.7	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.4	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1	0.3	GO:0046968	peptide antigen transport(GO:0046968)
0.1	0.2	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.9	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.1	0.5	GO:1901524	regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.1	0.5	GO:0022616	DNA strand elongation(GO:0022616)
0.1	0.4	GO:0035811	negative regulation of urine volume(GO:0035811)
0.1	0.3	GO:0032075	activation of signaling protein activity involved in unfolded protein response(GO:0006987) positive regulation of nuclease activity(GO:0032075)
0.1	0.8	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1	0.4	GO:0046035	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	1.3	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.8	GO:1903894	regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.1	0.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.1	GO:1990791	dorsal root ganglion development(GO:1990791)
0.1	0.8	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.1	0.3	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.1	0.4	GO:0001302	replicative cell aging(GO:0001302)
0.1	0.3	GO:0045931	positive regulation of mitotic cell cycle(GO:0045931)
0.1	2.9	GO:0009060	aerobic respiration(GO:0009060)
0.1	0.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	0.3	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1	0.7	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.1	0.3	GO:0044843	cell cycle G1/S phase transition(GO:0044843)
0.1	0.4	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	1.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	1.4	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.1	0.3	GO:0001927	exocyst assembly(GO:0001927)
0.1	0.1	GO:1903094	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1	1.5	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.1	0.3	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	0.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.3	GO:0007549	dosage compensation(GO:0007549)
0.1	0.2	GO:0021815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1	0.2	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.1	1.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.1	1.2	GO:0033108	mitochondrial respiratory chain complex assembly(GO:0033108)
0.1	2.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.1	0.2	GO:0048539	bone marrow development(GO:0048539)
0.1	0.4	GO:0045006	DNA deamination(GO:0045006)
0.1	0.5	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1	1.0	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.1	0.3	GO:0046033	AMP metabolic process(GO:0046033)
0.1	0.3	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1	0.2	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	0.2	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.1	0.2	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.1	0.5	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1	8.2	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1	0.2	GO:0071025	RNA surveillance(GO:0071025)
0.1	1.2	GO:0007020	microtubule nucleation(GO:0007020)
0.1	0.3	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.2	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.1	0.5	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1	0.7	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.1	1.2	GO:1903206	negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.1	0.5	GO:0050821	protein stabilization(GO:0050821)
0.1	0.8	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.1	0.1	GO:1901679	nucleotide transmembrane transport(GO:1901679)
0.1	1.8	GO:0051646	mitochondrion localization(GO:0051646)
0.1	1.4	GO:0035456	response to interferon-beta(GO:0035456)
0.1	1.2	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.5	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.5	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	1.0	GO:0070932	histone H3 deacetylation(GO:0070932)
0.1	2.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	1.9	GO:0031648	protein destabilization(GO:0031648)
0.1	0.3	GO:1900827	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	4.9	GO:0007062	sister chromatid cohesion(GO:0007062)
0.1	0.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.1	0.9	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.1	0.3	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	0.7	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1	0.8	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.1	0.3	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1	0.1	GO:0002369	T cell cytokine production(GO:0002369)
0.1	2.1	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.1	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.1	0.3	GO:0009099	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1	0.2	GO:0030578	PML body organization(GO:0030578)
0.1	0.3	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	0.2	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.6	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.2	GO:0003338	metanephros morphogenesis(GO:0003338)
0.1	0.6	GO:0010265	SCF complex assembly(GO:0010265)
0.1	0.1	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1	0.9	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.4	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.3	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1	0.2	GO:1901143	insulin catabolic process(GO:1901143)
0.1	0.3	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1	0.2	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.1	0.7	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	2.6	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.1	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.6	GO:0007519	skeletal muscle tissue development(GO:0007519) skeletal muscle organ development(GO:0060538)
0.1	0.1	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.1	0.1	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.1	0.3	GO:0001834	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1	0.4	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.1	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.3	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1	18.3	GO:0008380	RNA splicing(GO:0008380)
0.1	0.6	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.8	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	0.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	0.8	GO:0035878	nail development(GO:0035878)
0.1	1.4	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.1	1.5	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.1	0.1	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.1	0.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.3	GO:2000678	negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.1	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.2	GO:0006668	sphinganine-1-phosphate metabolic process(GO:0006668)
0.1	1.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.1	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1	0.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1	0.3	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	0.2	GO:0034205	beta-amyloid formation(GO:0034205)
0.1	0.1	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1	0.4	GO:0043627	response to estrogen(GO:0043627)
0.1	0.6	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.1	0.3	GO:0090650	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1	0.5	GO:0007512	adult heart development(GO:0007512)
0.1	0.3	GO:1903416	response to glycoside(GO:1903416)
0.1	0.3	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.1	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.1	0.4	GO:0030210	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.1	0.4	GO:0030091	protein repair(GO:0030091)
0.1	0.4	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.2	GO:0052422	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1	0.5	GO:0008340	determination of adult lifespan(GO:0008340)
0.1	0.2	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.2	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.1	0.5	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.1	0.2	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.1	0.2	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1	0.1	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.1	0.7	GO:0006768	biotin metabolic process(GO:0006768)
0.1	1.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	3.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.1	GO:2000374	regulation of oxygen metabolic process(GO:2000374)
0.1	0.3	GO:0000729	DNA double-strand break processing(GO:0000729)
0.1	0.2	GO:0035089	establishment of apical/basal cell polarity(GO:0035089)
0.1	0.6	GO:0006559	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.8	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.3	GO:0070255	regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1	0.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	0.4	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.3	GO:0006041	glucosamine metabolic process(GO:0006041)
0.1	1.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	1.2	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.1	0.2	GO:0072513	regulation of secondary heart field cardioblast proliferation(GO:0003266) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.4	GO:1901184	regulation of ERBB signaling pathway(GO:1901184)
0.1	0.4	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.1	0.1	GO:2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1	0.8	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.4	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.1	0.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1	0.1	GO:0009408	response to heat(GO:0009408)
0.1	0.3	GO:0017004	cytochrome complex assembly(GO:0017004)
0.1	0.3	GO:0022900	electron transport chain(GO:0022900)
0.1	0.4	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	0.5	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.1	0.5	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.2	GO:0042938	dipeptide transport(GO:0042938)
0.1	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.4	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.1	0.3	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	0.3	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	1.6	GO:0005980	glycogen catabolic process(GO:0005980)
0.1	0.6	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.1	2.2	GO:0030218	erythrocyte differentiation(GO:0030218)
0.1	0.2	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.1	0.2	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.1	0.1	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.3	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:1903659	complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659)
0.0	0.7	GO:0006012	galactose metabolic process(GO:0006012)
0.0	2.1	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.1	GO:0002584	negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0	1.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0	0.0	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.1	GO:0097475	motor neuron migration(GO:0097475)
0.0	2.4	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.1	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.1	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0	0.1	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.0	0.8	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	3.8	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0	0.1	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.0	0.0	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.0	0.2	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0	2.4	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.0	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0	0.7	GO:0006839	mitochondrial transport(GO:0006839)
0.0	0.1	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.0	0.4	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.2	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547) ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0	0.1	GO:0007538	primary sex determination(GO:0007538)
0.0	0.8	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.0	GO:0071907	determination of digestive tract left/right asymmetry(GO:0071907)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.4	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.3	GO:0006116	NADH oxidation(GO:0006116)
0.0	0.1	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.0	0.3	GO:0072537	fibroblast activation(GO:0072537)
0.0	0.1	GO:0071709	membrane assembly(GO:0071709)
0.0	0.7	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.2	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0	1.0	GO:0090280	positive regulation of calcium ion import(GO:0090280)
0.0	0.1	GO:0044743	intracellular protein transmembrane import(GO:0044743)
0.0	0.5	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.0	0.3	GO:0046898	response to cycloheximide(GO:0046898)
0.0	0.1	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0	2.2	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.0	0.1	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.0	0.2	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.3	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0	0.1	GO:0006835	dicarboxylic acid transport(GO:0006835)
0.0	0.9	GO:0045333	cellular respiration(GO:0045333)
0.0	5.2	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0	0.2	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0	0.5	GO:1904407	positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0	0.3	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.3	GO:0090659	walking behavior(GO:0090659)
0.0	0.6	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.0	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.2	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0	0.1	GO:0035624	receptor transactivation(GO:0035624)
0.0	0.1	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.0	0.2	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024)
0.0	0.0	GO:0034767	positive regulation of ion transmembrane transport(GO:0034767)
0.0	0.1	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
0.0	0.6	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.1	GO:0045575	basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0	0.9	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.2	GO:0006284	base-excision repair(GO:0006284)
0.0	0.1	GO:0098780	response to mitochondrial depolarisation(GO:0098780)
0.0	0.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.3	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.2	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.3	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.1	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0006304	DNA modification(GO:0006304)
0.0	0.1	GO:1904779	regulation of protein localization to centrosome(GO:1904779)
0.0	0.3	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.2	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.7	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.0	GO:0043276	anoikis(GO:0043276) regulation of anoikis(GO:2000209)
0.0	0.1	GO:0010212	response to ionizing radiation(GO:0010212)
0.0	0.3	GO:0006568	tryptophan metabolic process(GO:0006568)
0.0	0.3	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.3	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.2	GO:0006909	phagocytosis(GO:0006909)
0.0	0.1	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.1	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.0	1.1	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0	0.3	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.2	GO:0016525	negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0	0.3	GO:0006366	transcription from RNA polymerase II promoter(GO:0006366)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:2000845	androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	3.9	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.9	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.4	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0009593	detection of chemical stimulus(GO:0009593)
0.0	0.1	GO:2001300	lipoxin metabolic process(GO:2001300)
0.0	0.1	GO:0045324	late endosome to vacuole transport(GO:0045324)
0.0	0.2	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.1	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.0	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0	0.0	GO:0035962	response to interleukin-13(GO:0035962)
0.0	0.2	GO:0017085	response to insecticide(GO:0017085)
0.0	0.3	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.3	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.8	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.1	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.0	0.4	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.0	GO:1904386	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0	0.0	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.9	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0006862	nucleotide transport(GO:0006862)
0.0	0.6	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.4	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	0.3	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.4	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0	0.1	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.1	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.2	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0032652	regulation of interleukin-1 production(GO:0032652)
0.0	0.2	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.1	GO:0002287	alpha-beta T cell activation involved in immune response(GO:0002287) T cell differentiation involved in immune response(GO:0002292) alpha-beta T cell differentiation involved in immune response(GO:0002293) CD4-positive, alpha-beta T cell differentiation involved in immune response(GO:0002294) T-helper cell differentiation(GO:0042093) T-helper 1 cell differentiation(GO:0045063)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.0	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.0	0.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.1	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.2	GO:0042391	regulation of membrane potential(GO:0042391)
0.0	0.1	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.0	0.3	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.1	GO:0015909	fatty acid transport(GO:0015908) long-chain fatty acid transport(GO:0015909)
0.0	0.1	GO:0018210	peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0	0.9	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.3	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0	0.8	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0021586	pons maturation(GO:0021586)
0.0	0.1	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.1	GO:0033864	positive regulation of NAD(P)H oxidase activity(GO:0033864)
0.0	0.2	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.0	0.2	GO:1903859	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0	0.4	GO:0010039	response to iron ion(GO:0010039)
0.0	0.2	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.3	GO:0071800	podosome assembly(GO:0071800)
0.0	0.7	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0036343	psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.0	0.2	GO:0010870	positive regulation of receptor biosynthetic process(GO:0010870)
0.0	0.1	GO:0061107	seminal vesicle development(GO:0061107)
0.0	0.0	GO:0021700	developmental maturation(GO:0021700)
0.0	0.2	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.0	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.1	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
0.0	0.8	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.0	0.1	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0	0.3	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	1.8	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:2001053	regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0	0.0	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0003016	respiratory system process(GO:0003016)
0.0	0.4	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.1	GO:0043555	negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057) regulation of translation in response to stress(GO:0043555) regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0001714	endodermal cell fate specification(GO:0001714)
0.0	0.2	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0	0.2	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.0	GO:0036269	swimming behavior(GO:0036269)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.0	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.1	GO:0035815	positive regulation of renal sodium excretion(GO:0035815)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	0.0	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.0	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) regulation of rubidium ion transmembrane transporter activity(GO:2000686) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0	0.6	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.3	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0	0.9	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.2	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	1.0	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.1	GO:0021762	substantia nigra development(GO:0021762)
0.0	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.5	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.2	GO:0006112	energy reserve metabolic process(GO:0006112)
0.0	0.1	GO:0051697	protein delipidation(GO:0051697)
0.0	0.2	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.0	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.1	GO:0006415	translational termination(GO:0006415)
0.0	0.0	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.2	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0030261	chromosome condensation(GO:0030261)
0.0	0.1	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.0	0.7	GO:0071158	positive regulation of cell cycle arrest(GO:0071158)
0.0	0.2	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.0	0.0	GO:0010663	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0	0.4	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.3	GO:0097503	sialylation(GO:0097503)
0.0	0.0	GO:0003352	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.0	0.1	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.0	GO:0097350	neutrophil clearance(GO:0097350)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.1	GO:1901983	regulation of protein acetylation(GO:1901983)
0.0	0.4	GO:0016573	histone acetylation(GO:0016573)
0.0	0.0	GO:1902723	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.0	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300) negative regulation of intestinal absorption(GO:1904479) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.0	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.2	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.0	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.0	GO:0042095	interferon-gamma biosynthetic process(GO:0042095) regulation of interferon-gamma biosynthetic process(GO:0045072)
0.0	0.3	GO:0034776	response to histamine(GO:0034776)
0.0	0.0	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.0	0.0	GO:0048535	lymph node development(GO:0048535)
0.0	0.1	GO:0002819	regulation of adaptive immune response(GO:0002819)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0051410	detoxification of nitrogen compound(GO:0051410)
0.0	0.0	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.9	GO:0030282	bone mineralization(GO:0030282)
0.0	0.0	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:0001709	cell fate determination(GO:0001709)
0.0	0.3	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.4	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.2	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:0032094	response to food(GO:0032094)
0.0	0.0	GO:1900180	regulation of protein localization to nucleus(GO:1900180)
0.0	0.1	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.0	0.0	GO:0042560	folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.2	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0035116	embryonic hindlimb morphogenesis(GO:0035116)
0.0	0.1	GO:0031365	N-terminal protein amino acid modification(GO:0031365)
0.0	0.1	GO:0033239	negative regulation of cellular amine metabolic process(GO:0033239)
0.0	0.0	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.0	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.1	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.1	GO:0035088	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	0.1	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	3.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	3.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.4	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	2.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.4	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.9	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	2.9	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.4	5.6	GO:0006089	lactate metabolic process(GO:0006089)
0.3	1.6	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
0.2	0.9	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.2	0.5	GO:0052510	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1	0.8	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.4	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.1	0.3	GO:0036371	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1	0.9	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.1	0.8	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.0	0.9	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.0	0.1	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.0	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	1.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	5.5	GO:0050436	microfibril binding(GO:0050436)
0.7	8.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.7	2.7	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.5	1.6	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.5	9.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.3	1.4	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.2	4.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.2	3.3	GO:0019215	intermediate filament binding(GO:0019215)
0.2	0.6	GO:0061714	folic acid receptor activity(GO:0061714)
0.1	0.4	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	3.9	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	4.1	GO:0005109	frizzled binding(GO:0005109)
0.1	3.8	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	2.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	0.3	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	13.4	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	2.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	4.0	GO:0003785	actin monomer binding(GO:0003785)
0.1	4.7	GO:0019894	kinesin binding(GO:0019894)
0.1	0.3	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.9	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	1.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.6	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	0.6	GO:0035497	cAMP response element binding(GO:0035497)
0.1	1.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	2.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.7	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.3	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	1.0	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.8	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	2.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	1.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	1.0	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.3	GO:0031433	telethonin binding(GO:0031433)
0.0	2.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	9.5	GO:0005543	phospholipid binding(GO:0005543)
0.0	0.3	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.4	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	1.0	GO:0005518	collagen binding(GO:0005518)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	3.1	GO:0016757	transferase activity, transferring glycosyl groups(GO:0016757)
0.0	1.8	GO:0019838	growth factor binding(GO:0019838)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	3.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.2	2.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	3.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	2.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	0.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	3.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	1.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	0.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	2.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	1.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	2.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	1.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.4	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	5.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	2.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	1.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.0	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.0	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.3	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.2	0.7	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	2.0	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.4	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1	0.8	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.1	0.3	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.1	0.4	GO:0000811	GINS complex(GO:0000811)
0.1	0.3	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	0.4	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0005873	plus-end kinesin complex(GO:0005873)
0.1	0.9	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.7	GO:0033391	chromatoid body(GO:0033391)
0.1	0.4	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	0.2	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	0.3	GO:0061617	MICOS complex(GO:0061617)
0.0	0.3	GO:0071817	MMXD complex(GO:0071817)
0.0	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.4	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.3	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.0	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.1	21.4	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
5.5	16.6	GO:0070052	collagen V binding(GO:0070052)
4.1	12.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
3.1	67.2	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
2.5	61.0	GO:0001968	fibronectin binding(GO:0001968)
2.1	8.5	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
2.1	58.1	GO:0005523	tropomyosin binding(GO:0005523)
1.9	7.7	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.7	12.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
1.1	21.7	GO:0033130	acetylcholine receptor binding(GO:0033130)
1.1	34.0	GO:0005212	structural constituent of eye lens(GO:0005212)
1.1	5.3	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0	18.5	GO:0045295	gamma-catenin binding(GO:0045295)
0.9	10.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.9	2.7	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.8	20.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.8	11.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.8	3.2	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.7	2.7	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.7	65.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.6	1.3	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.5	5.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.5	15.7	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.5	3.6	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.4	1.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.4	4.7	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.4	2.7	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.4	1.6	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3	2.7	GO:0031014	troponin T binding(GO:0031014)
0.3	30.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.3	3.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3	1.6	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.3	5.8	GO:0030506	ankyrin binding(GO:0030506)
0.3	3.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.3	2.7	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.3	1.7	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3	5.5	GO:0005003	ephrin receptor activity(GO:0005003)
0.3	13.7	GO:0016504	peptidase activator activity(GO:0016504)
0.3	2.6	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.3	1.0	GO:0004348	glucosylceramidase activity(GO:0004348)
0.2	1.0	GO:0038132	neuregulin binding(GO:0038132)
0.2	2.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.2	0.7	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.2	3.4	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.2	4.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	7.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.2	0.6	GO:0004769	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.2	0.8	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2	0.7	GO:0015232	heme transporter activity(GO:0015232)
0.2	1.4	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.2	0.8	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	14.6	GO:0032947	protein complex scaffold(GO:0032947)
0.1	0.7	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.5	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	4.3	GO:0001972	retinoic acid binding(GO:0001972)
0.1	11.4	GO:0051219	phosphoprotein binding(GO:0051219)
0.1	5.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	5.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	1.7	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	2.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	1.8	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.1	11.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	1.3	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.1	1.5	GO:0045499	chemorepellent activity(GO:0045499)
0.1	6.8	GO:0017022	myosin binding(GO:0017022)
0.1	10.2	GO:0019838	growth factor binding(GO:0019838)
0.1	2.8	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	1.1	GO:0017166	vinculin binding(GO:0017166)
0.1	1.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.2	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	3.0	GO:0019894	kinesin binding(GO:0019894)
0.1	9.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	3.8	GO:0097110	scaffold protein binding(GO:0097110)
0.1	4.7	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	5.7	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.1	0.3	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1	4.2	GO:0019003	GDP binding(GO:0019003)
0.1	0.4	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	1.1	GO:0019864	IgG binding(GO:0019864)
0.1	1.5	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.2	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.1	1.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.4	GO:0050733	RS domain binding(GO:0050733)
0.1	0.3	GO:0009378	four-way junction helicase activity(GO:0009378)
0.1	3.8	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.0	1.0	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.3	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	1.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.3	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	2.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	1.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.7	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	11.6	GO:0003924	GTPase activity(GO:0003924)
0.0	0.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	1.9	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	2.4	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.1	GO:0015403	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.6	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	3.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	5.6	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	1.0	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.5	GO:0005537	mannose binding(GO:0005537)
0.0	0.2	GO:0032190	acrosin binding(GO:0032190)
0.0	0.6	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	1.2	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.7	GO:0004857	enzyme inhibitor activity(GO:0004857)
0.0	0.2	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0	1.0	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.7	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	4.8	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	3.9	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.4	GO:0017124	SH3 domain binding(GO:0017124)
0.0	3.2	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.6	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.2	GO:0031005	filamin binding(GO:0031005)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	11.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	3.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	3.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.8	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.5	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	2.0	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	3.0	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	3.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	1.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0051185	FAD transmembrane transporter activity(GO:0015230) coenzyme transporter activity(GO:0051185)
0.3	0.8	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	0.6	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.2	1.1	GO:0042610	CD8 receptor binding(GO:0042610)
0.2	0.5	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.1	2.2	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.5	GO:0097001	ceramide binding(GO:0097001)
0.1	0.3	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.3	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1	0.6	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.8	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	0.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.1	0.5	GO:0008948	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1	0.9	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.4	GO:0051373	FATZ binding(GO:0051373)
0.1	1.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.2	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	0.2	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	1.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.7	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.6	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.2	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.1	0.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.4	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.5	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.4	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.4	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	1.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.5	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.8	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	1.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0004307	diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.3	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.6	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0004819	glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0	0.2	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.7	GO:0070412	R-SMAD binding(GO:0070412)
0.0	1.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	2.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	1.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.8	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.3	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.5	GO:0097493	muscle alpha-actinin binding(GO:0051371) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.1	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0000150	recombinase activity(GO:0000150)
0.0	0.1	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0	0.1	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.1	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.3	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.0	1.5	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.8	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.3	GO:0071949	FAD binding(GO:0071949)
0.0	0.0	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.5	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.0	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.8	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.4	2.1	GO:0001652	granular component(GO:0001652)
0.3	2.4	GO:0016012	sarcoglycan complex(GO:0016012)
0.3	0.8	GO:0020003	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.3	0.8	GO:0005588	collagen type V trimer(GO:0005588)
0.3	2.0	GO:0000322	storage vacuole(GO:0000322)
0.2	0.9	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2	0.8	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.2	0.5	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1	2.1	GO:0097512	cardiac myofibril(GO:0097512)
0.1	1.5	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	1.9	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	2.2	GO:0042599	lamellar body(GO:0042599)
0.1	0.4	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:1990761	growth cone lamellipodium(GO:1990761)
0.1	0.6	GO:0032280	symmetric synapse(GO:0032280)
0.1	0.7	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.1	1.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.8	GO:0005955	calcineurin complex(GO:0005955)
0.1	3.2	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.5	GO:0008537	proteasome activator complex(GO:0008537)
0.1	7.1	GO:0031594	neuromuscular junction(GO:0031594)
0.1	0.4	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.4	GO:0071203	WASH complex(GO:0071203)
0.0	0.5	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.6	GO:0030478	actin cap(GO:0030478)
0.0	1.9	GO:0097542	ciliary tip(GO:0097542)
0.0	0.3	GO:0031415	NatA complex(GO:0031415)
0.0	0.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	2.9	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	3.0	GO:0005902	microvillus(GO:0005902)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	11.0	GO:0019898	extrinsic component of membrane(GO:0019898)
0.0	4.2	GO:0008021	synaptic vesicle(GO:0008021)
0.0	1.8	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	2.5	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	1.9	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	2.3	GO:0044853	plasma membrane raft(GO:0044853)
0.0	2.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	2.0	GO:0030175	filopodium(GO:0030175)
0.0	0.8	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	4.1	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.4	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.2	GO:0005833	hemoglobin complex(GO:0005833)
0.0	1.0	GO:0016324	apical plasma membrane(GO:0016324)
0.0	1.0	GO:0043204	perikaryon(GO:0043204)
0.0	4.0	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	1.1	GO:0000502	proteasome complex(GO:0000502)
0.0	0.4	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.6	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.8	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	0.2	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.6	GO:0005881	cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	1.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	13.1	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.8	6.7	GO:0097208	alveolar lamellar body(GO:0097208)
0.7	2.8	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.7	6.9	GO:0097413	Lewy body(GO:0097413)
0.5	1.5	GO:0019034	viral replication complex(GO:0019034)
0.4	1.8	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.4	1.7	GO:1990246	uniplex complex(GO:1990246)
0.4	1.2	GO:0005588	collagen type V trimer(GO:0005588)
0.4	3.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.4	4.8	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.3	3.8	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.3	1.7	GO:0005899	insulin receptor complex(GO:0005899)
0.3	0.9	GO:0005879	axonemal microtubule(GO:0005879)
0.3	2.0	GO:1990812	growth cone filopodium(GO:1990812)
0.3	4.8	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.3	1.6	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.2	1.1	GO:0033263	CORVET complex(GO:0033263)
0.2	1.1	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.2	3.3	GO:0005916	fascia adherens(GO:0005916)
0.2	0.6	GO:1903349	omegasome membrane(GO:1903349)
0.2	3.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	25.9	GO:0043202	lysosomal lumen(GO:0043202)
0.2	0.9	GO:0097470	ribbon synapse(GO:0097470)
0.2	2.4	GO:0097227	sperm annulus(GO:0097227)
0.2	1.0	GO:0030991	intraciliary transport particle A(GO:0030991)
0.2	1.1	GO:0097452	GAIT complex(GO:0097452)
0.1	1.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.1	11.8	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	1.9	GO:0031209	SCAR complex(GO:0031209)
0.1	0.8	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	3.6	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	1.6	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	1.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	0.5	GO:0070985	TFIIK complex(GO:0070985)
0.1	0.8	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.1	0.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	6.2	GO:0016235	aggresome(GO:0016235)
0.1	1.3	GO:0060077	inhibitory synapse(GO:0060077)
0.1	9.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.6	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.5	GO:0031089	platelet dense granule lumen(GO:0031089)
0.1	0.7	GO:0097165	nuclear stress granule(GO:0097165)
0.1	2.2	GO:0002102	podosome(GO:0002102)
0.1	0.7	GO:0036157	outer dynein arm(GO:0036157)
0.1	4.5	GO:0005844	polysome(GO:0005844)
0.1	0.8	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	5.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.9	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.1	7.7	GO:0005901	caveola(GO:0005901)
0.1	0.6	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.1	0.5	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	1.0	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.1	0.5	GO:0000322	storage vacuole(GO:0000322)
0.1	0.4	GO:0071203	WASH complex(GO:0071203)
0.1	4.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	3.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.1	0.3	GO:0000801	central element(GO:0000801)
0.1	1.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	1.0	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	0.2	GO:0002177	manchette(GO:0002177)
0.1	0.3	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.0	1.3	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	1.0	GO:0071141	SMAD protein complex(GO:0071141)
0.0	1.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.5	GO:0030897	HOPS complex(GO:0030897)
0.0	0.6	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.7	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	3.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.4	GO:0005579	membrane attack complex(GO:0005579)
0.0	1.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.6	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.6	GO:0097440	apical dendrite(GO:0097440)
0.0	12.7	GO:0005938	cell cortex(GO:0005938)
0.0	1.0	GO:0009925	basal plasma membrane(GO:0009925)
0.0	1.2	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.3	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	2.9	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	1.8	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.7	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.9	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.5	GO:0005922	connexon complex(GO:0005922)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.5	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	8.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.8	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	1.4	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.6	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	2.8	GO:0032587	ruffle membrane(GO:0032587)
0.0	2.6	GO:0005814	centriole(GO:0005814)
0.0	1.5	GO:0005604	basement membrane(GO:0005604)
0.0	0.6	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.4	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	1.3	GO:0005811	lipid particle(GO:0005811)
0.0	1.2	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.0	2.8	GO:0030496	midbody(GO:0030496)
0.0	0.9	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.4	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.9	GO:0000152	nuclear ubiquitin ligase complex(GO:0000152)
0.0	0.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	5.5	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.4	GO:0030057	desmosome(GO:0030057)
0.0	0.4	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	1.7	GO:0005770	late endosome(GO:0005770)
0.0	0.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.4	GO:0005682	U5 snRNP(GO:0005682)
0.0	1.4	GO:0031514	motile cilium(GO:0031514)
0.0	0.0	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.3	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.2	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.6	GO:0060621	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.4	0.8	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.3	1.4	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.3	0.9	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.3	0.8	GO:0006864	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.3	2.5	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.2	0.8	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.2	1.5	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2	1.2	GO:1901526	negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.2	0.5	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2	0.6	GO:0042412	taurine biosynthetic process(GO:0042412)
0.1	0.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.6	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.4	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.4	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.5	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.7	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	3.2	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	0.6	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.1	0.3	GO:0071233	cellular response to leucine(GO:0071233)
0.1	0.2	GO:1900239	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	0.3	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0	0.4	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.2	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.4	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	1.6	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0042418	epinephrine biosynthetic process(GO:0042418)
0.0	1.1	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.4	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.2	GO:0051451	myoblast migration(GO:0051451)
0.0	0.2	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0032972	regulation of muscle filament sliding(GO:0032971) regulation of muscle filament sliding speed(GO:0032972)
0.0	0.2	GO:1901018	positive regulation of potassium ion transmembrane transporter activity(GO:1901018)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.9	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	2.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	3.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.8	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.8	GO:0035378	carbon dioxide transmembrane transport(GO:0035378)
0.3	1.3	GO:0097476	NMDA glutamate receptor clustering(GO:0097114) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2	1.0	GO:0035549	positive regulation of interferon-beta secretion(GO:0035549)
0.2	1.7	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	0.8	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.1	0.3	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	0.4	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.7	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.1	0.7	GO:0015816	glycine transport(GO:0015816)
0.1	0.2	GO:0035470	positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.1	0.3	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.1	0.6	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	0.7	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.3	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
0.1	0.3	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1	0.6	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.4	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.4	GO:0016926	protein desumoylation(GO:0016926)
0.0	1.0	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	1.2	GO:0061014	positive regulation of mRNA catabolic process(GO:0061014)
0.0	0.5	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.2	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.6	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.4	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0	0.5	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	1.3	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0	1.7	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.8	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.8	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.0	0.2	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.8	17.4	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
4.9	19.6	GO:1902613	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
4.7	23.3	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
4.4	4.4	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354) thorax and anterior abdomen determination(GO:0007356) metanephric part of ureteric bud development(GO:0035502) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
3.8	11.3	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
3.6	3.6	GO:0048807	female genitalia morphogenesis(GO:0048807)
3.3	39.3	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
3.2	19.1	GO:0061441	renal artery morphogenesis(GO:0061441)
3.2	12.6	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
3.0	12.0	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
3.0	20.8	GO:0071896	protein localization to adherens junction(GO:0071896)
2.8	8.3	GO:0051541	elastin metabolic process(GO:0051541)
2.8	25.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
2.7	10.7	GO:2000230	negative regulation of pancreatic stellate cell proliferation(GO:2000230)
2.6	23.2	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.5	10.2	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
2.4	7.3	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
2.4	9.5	GO:0021564	vagus nerve development(GO:0021564)
2.4	4.7	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
2.4	61.2	GO:0071294	cellular response to zinc ion(GO:0071294)
2.3	7.0	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
2.3	11.6	GO:0030047	actin modification(GO:0030047)
2.3	11.6	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
2.3	4.6	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
2.2	2.2	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
2.2	8.8	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
2.2	15.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
2.2	17.4	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
2.2	6.5	GO:0001923	B-1 B cell differentiation(GO:0001923)
2.2	8.6	GO:1904566	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
2.1	12.9	GO:0007386	compartment pattern specification(GO:0007386)
2.1	10.7	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
2.1	23.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
2.1	2.1	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.1	8.3	GO:0035879	plasma membrane lactate transport(GO:0035879)
2.0	20.4	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
2.0	5.9	GO:0071409	cellular response to cycloheximide(GO:0071409)
2.0	15.6	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
1.9	5.8	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.9	3.9	GO:0007412	axon target recognition(GO:0007412)
1.9	7.6	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.9	20.6	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
1.9	3.8	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.9	9.3	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
1.8	12.8	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
1.8	3.7	GO:1905123	regulation of glucosylceramidase activity(GO:1905123)
1.8	8.9	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
1.8	5.3	GO:1903465	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.7	5.2	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
1.7	5.2	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.7	27.4	GO:0051639	actin filament network formation(GO:0051639)
1.7	6.8	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
1.7	6.8	GO:0046086	adenosine biosynthetic process(GO:0046086)
1.7	6.7	GO:0042412	taurine biosynthetic process(GO:0042412)
1.7	10.0	GO:1903921	protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
1.6	1.6	GO:0071306	cellular response to vitamin E(GO:0071306)
1.6	3.2	GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
1.6	6.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
1.6	17.4	GO:0034465	response to carbon monoxide(GO:0034465)
1.6	1.6	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
1.6	4.7	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.6	7.8	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
1.5	1.5	GO:0010159	specification of organ position(GO:0010159)
1.5	4.6	GO:2000521	negative regulation of immunological synapse formation(GO:2000521)
1.5	4.6	GO:0021966	corticospinal neuron axon guidance(GO:0021966)
1.5	15.3	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
1.5	4.6	GO:0032474	otolith morphogenesis(GO:0032474)
1.5	4.5	GO:0090427	activation of meiosis(GO:0090427)
1.5	1.5	GO:0035973	aggrephagy(GO:0035973)
1.5	4.5	GO:0060437	lung growth(GO:0060437)
1.5	1.5	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.5	6.0	GO:1902462	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.5	4.4	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
1.5	7.4	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
1.5	1.5	GO:0060221	retinal rod cell differentiation(GO:0060221)
1.5	4.4	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.5	8.7	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
1.5	4.4	GO:0023016	signal transduction by trans-phosphorylation(GO:0023016)
1.4	4.3	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
1.4	1.4	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
1.4	4.3	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.4	1.4	GO:0035989	tendon development(GO:0035989)
1.4	5.5	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
1.4	5.5	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
1.4	13.7	GO:0070141	response to UV-A(GO:0070141)
1.4	4.1	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
1.4	14.9	GO:0009414	response to water deprivation(GO:0009414)
1.3	1.3	GO:0097237	cellular response to toxic substance(GO:0097237)
1.3	6.6	GO:0018158	protein oxidation(GO:0018158)
1.3	6.6	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
1.3	4.0	GO:0018008	N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
1.3	3.9	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
1.3	11.7	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
1.3	9.0	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
1.3	5.1	GO:0060434	bronchus morphogenesis(GO:0060434)
1.3	6.3	GO:0048625	myoblast fate commitment(GO:0048625)
1.3	8.8	GO:0089700	protein kinase D signaling(GO:0089700)
1.3	10.0	GO:0097039	protein linear polyubiquitination(GO:0097039)
1.2	5.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.2	8.7	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.2	3.7	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)
1.2	8.7	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.2	8.6	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
1.2	12.3	GO:0036155	acylglycerol acyl-chain remodeling(GO:0036155)
1.2	6.1	GO:0030035	microspike assembly(GO:0030035)
1.2	4.9	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
1.2	18.2	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
1.2	4.8	GO:0046108	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
1.2	4.8	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
1.2	3.6	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
1.2	1.2	GO:0060364	frontal suture morphogenesis(GO:0060364)
1.2	5.9	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
1.2	3.5	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
1.2	5.8	GO:1901628	positive regulation of postsynaptic membrane organization(GO:1901628)
1.2	1.2	GO:1903384	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
1.1	6.9	GO:0048549	positive regulation of pinocytosis(GO:0048549)
1.1	8.0	GO:0070294	renal sodium ion absorption(GO:0070294)
1.1	1.1	GO:0010040	response to iron(II) ion(GO:0010040)
1.1	4.6	GO:0035026	leading edge cell differentiation(GO:0035026)
1.1	1.1	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.1	9.1	GO:0006526	arginine biosynthetic process(GO:0006526)
1.1	2.3	GO:0061643	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
1.1	32.5	GO:0031581	hemidesmosome assembly(GO:0031581)
1.1	3.4	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
1.1	4.4	GO:0097049	motor neuron apoptotic process(GO:0097049)
1.1	3.3	GO:0032596	protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
1.1	4.4	GO:2000479	regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.1	7.7	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
1.1	2.2	GO:1900046	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
1.1	3.3	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
1.1	17.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
1.1	5.3	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
1.1	4.3	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
1.1	1.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
1.1	3.2	GO:0019417	sulfur oxidation(GO:0019417)
1.1	2.1	GO:0033484	nitric oxide homeostasis(GO:0033484)
1.0	3.1	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
1.0	5.2	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.0	2.0	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
1.0	6.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0	6.0	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.0	3.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.0	9.0	GO:0071692	sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
1.0	4.0	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
1.0	19.7	GO:0046697	decidualization(GO:0046697)
1.0	1.0	GO:0007032	endosome organization(GO:0007032)
1.0	1.0	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.0	2.9	GO:0045210	FasL biosynthetic process(GO:0045210)
1.0	15.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
1.0	2.9	GO:0033341	regulation of collagen binding(GO:0033341)
1.0	11.4	GO:0022417	protein maturation by protein folding(GO:0022417)
1.0	1.0	GO:0034333	adherens junction assembly(GO:0034333)
1.0	5.7	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.9	0.9	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.9	7.5	GO:0046618	drug export(GO:0046618)
0.9	2.8	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.9	2.8	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.9	5.6	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.9	2.8	GO:0060486	Clara cell differentiation(GO:0060486)
0.9	3.7	GO:0000103	sulfate assimilation(GO:0000103)
0.9	7.4	GO:0008090	retrograde axonal transport(GO:0008090)
0.9	3.7	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.9	1.8	GO:0097475	motor neuron migration(GO:0097475)
0.9	0.9	GO:0021636	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.9	1.8	GO:2000542	negative regulation of cell fate specification(GO:0009996) negative regulation of gastrulation(GO:2000542)
0.9	1.8	GO:0000050	urea cycle(GO:0000050)
0.9	2.7	GO:0018197	peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.9	4.5	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.9	0.9	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.9	3.6	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.9	2.7	GO:0014028	notochord formation(GO:0014028)
0.9	1.8	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.9	12.2	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.9	3.5	GO:0072144	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
0.9	5.2	GO:0070836	caveola assembly(GO:0070836)
0.9	4.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.9	7.8	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.9	21.5	GO:0033622	integrin activation(GO:0033622)
0.9	2.6	GO:0061386	closure of optic fissure(GO:0061386)
0.9	1.7	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.9	3.4	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.8	7.6	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.8	3.4	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.8	2.5	GO:0090298	negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.8	2.5	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.8	4.1	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.8	8.2	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.8	2.5	GO:0072602	interleukin-4 secretion(GO:0072602)
0.8	2.5	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.8	5.7	GO:0002934	desmosome organization(GO:0002934)
0.8	6.5	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.8	0.8	GO:0060157	urinary bladder development(GO:0060157)
0.8	2.4	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.8	3.2	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.8	2.4	GO:0009183	purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.8	7.2	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.8	2.4	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.8	0.8	GO:1903758	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.8	2.4	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.8	0.8	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.8	2.4	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.8	2.4	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.8	16.5	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.8	14.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.8	4.6	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.8	9.3	GO:0001778	plasma membrane repair(GO:0001778)
0.8	3.8	GO:0060325	face morphogenesis(GO:0060325)
0.8	1.5	GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901213)
0.8	3.8	GO:0042713	sperm ejaculation(GO:0042713)
0.8	6.1	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.8	7.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.8	6.0	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.8	6.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.8	6.8	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.8	3.8	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.8	3.0	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.7	3.0	GO:1990535	neuron projection maintenance(GO:1990535)
0.7	5.2	GO:0038129	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.7	4.5	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.7	7.5	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.7	3.7	GO:0010269	response to selenium ion(GO:0010269)
0.7	10.4	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.7	2.2	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.7	31.9	GO:0035329	hippo signaling(GO:0035329)
0.7	13.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.7	4.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.7	2.9	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.7	2.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.7	4.3	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.7	2.2	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.7	2.2	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.7	2.9	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.7	2.9	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.7	2.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.7	2.9	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.7	1.4	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.7	4.3	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.7	12.8	GO:0043476	pigment accumulation(GO:0043476) cellular pigment accumulation(GO:0043482)
0.7	1.4	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.7	2.8	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.7	7.8	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.7	1.4	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.7	3.5	GO:0001705	ectoderm formation(GO:0001705)
0.7	25.8	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.7	1.4	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.7	11.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.7	3.4	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.7	2.0	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.7	8.8	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.7	2.7	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.7	0.7	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.7	6.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.7	5.3	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.7	6.6	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.7	2.0	GO:1904530	regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.7	1.3	GO:0003285	septum secundum development(GO:0003285)
0.7	0.7	GO:0071211	protein targeting to vacuole involved in autophagy(GO:0071211)
0.7	13.7	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.6	2.6	GO:0034436	glycoprotein transport(GO:0034436)
0.6	1.3	GO:0001765	membrane raft assembly(GO:0001765)
0.6	0.6	GO:0006907	pinocytosis(GO:0006907)
0.6	1.9	GO:1900075	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.6	3.8	GO:0061518	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6	1.9	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.6	9.6	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.6	0.6	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.6	2.5	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.6	2.5	GO:0048749	compound eye development(GO:0048749)
0.6	1.3	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.6	2.5	GO:0002086	maltose metabolic process(GO:0000023) diaphragm contraction(GO:0002086)
0.6	3.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.6	14.2	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.6	4.9	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.6	4.3	GO:0042908	xenobiotic transport(GO:0042908)
0.6	8.0	GO:0097320	membrane tubulation(GO:0097320)
0.6	1.2	GO:2000910	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.6	3.0	GO:1990504	dense core granule exocytosis(GO:1990504)
0.6	0.6	GO:1904398	positive regulation of neuromuscular junction development(GO:1904398)
0.6	2.4	GO:1904450	negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.6	0.6	GO:0031345	negative regulation of cell projection organization(GO:0031345)
0.6	19.3	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.6	9.7	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.6	1.8	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.6	4.8	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.6	1.8	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.6	5.3	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.6	4.7	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.6	1.2	GO:1902534	single-organism membrane invagination(GO:1902534)
0.6	4.0	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.6	1.7	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.6	0.6	GO:0003306	Wnt signaling pathway involved in heart development(GO:0003306)
0.6	8.0	GO:0000052	citrulline metabolic process(GO:0000052)
0.6	3.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.6	0.6	GO:0055007	cardiac muscle cell differentiation(GO:0055007)
0.6	2.3	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.6	0.6	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.6	1.7	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.6	3.4	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.6	1.7	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
0.6	1.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6	0.6	GO:0050968	detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.6	0.6	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.6	2.8	GO:0051414	response to cortisol(GO:0051414)
0.5	3.3	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.5	1.6	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.5	2.2	GO:0099542	trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.5	7.6	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.5	2.2	GO:1903412	response to bile acid(GO:1903412)
0.5	1.6	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.5	2.2	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.5	3.2	GO:0051012	microtubule sliding(GO:0051012)
0.5	7.9	GO:0031643	positive regulation of myelination(GO:0031643)
0.5	1.6	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.5	0.5	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.5	1.6	GO:0035115	embryonic forelimb morphogenesis(GO:0035115) forelimb morphogenesis(GO:0035136)
0.5	4.7	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.5	3.1	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.5	6.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.5	0.5	GO:0048675	axon extension(GO:0048675)
0.5	3.1	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.5	1.5	GO:0061188	negative regulation of chromatin silencing at rDNA(GO:0061188)
0.5	6.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.5	5.1	GO:0060137	maternal process involved in parturition(GO:0060137)
0.5	1.5	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5	1.5	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5	2.0	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.5	1.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.5	1.0	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.5	1.0	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.5	6.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.5	1.5	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.5	2.0	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.5	2.5	GO:0071498	cellular response to fluid shear stress(GO:0071498)
0.5	0.5	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.5	3.5	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.5	1.5	GO:0071140	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.5	4.4	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.5	1.5	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5	1.5	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.5	1.0	GO:1905214	regulation of mRNA binding(GO:1902415) regulation of RNA binding(GO:1905214)
0.5	3.4	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.5	4.8	GO:0014870	response to muscle inactivity(GO:0014870)
0.5	2.9	GO:0032328	alanine transport(GO:0032328)
0.5	1.4	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.5	2.9	GO:0072719	cellular response to cisplatin(GO:0072719)
0.5	0.5	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.5	1.9	GO:0090164	asymmetric Golgi ribbon formation(GO:0090164)
0.5	15.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.5	4.7	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.5	2.4	GO:1903243	negative regulation of cardiac muscle adaptation(GO:0010616) transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.5	0.9	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.5	1.4	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.5	1.9	GO:0061290	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.5	0.5	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.5	2.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.5	1.9	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.5	9.3	GO:0071711	basement membrane organization(GO:0071711)
0.5	1.4	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.5	3.2	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5	1.4	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.5	0.9	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.5	1.8	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.5	1.8	GO:0009956	radial pattern formation(GO:0009956)
0.5	4.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.5	1.8	GO:0010814	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.5	3.6	GO:0006013	mannose metabolic process(GO:0006013)
0.5	2.7	GO:0010734	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.5	1.4	GO:1902617	response to fluoride(GO:1902617)
0.4	1.8	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.4	19.8	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.4	0.4	GO:0030104	water homeostasis(GO:0030104)
0.4	2.7	GO:0023041	neuronal signal transduction(GO:0023041)
0.4	5.8	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.4	0.9	GO:0014002	astrocyte development(GO:0014002)
0.4	5.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.4	0.9	GO:0032757	positive regulation of interleukin-8 production(GO:0032757)
0.4	0.9	GO:0061218	negative regulation of mesonephros development(GO:0061218)
0.4	1.7	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.4	3.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.4	0.4	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.4	0.9	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.4	4.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.4	9.1	GO:0003334	keratinocyte development(GO:0003334)
0.4	1.3	GO:1990108	protein linear deubiquitination(GO:1990108)
0.4	3.4	GO:0051764	actin crosslink formation(GO:0051764)
0.4	4.3	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.4	1.3	GO:0034063	stress granule assembly(GO:0034063)
0.4	0.8	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.4	2.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.4	0.8	GO:0006258	UDP-glucose catabolic process(GO:0006258)
0.4	0.4	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.4	2.5	GO:0001692	histamine metabolic process(GO:0001692)
0.4	1.3	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.4	1.6	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.4	1.6	GO:0009227	UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.4	2.0	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4	1.2	GO:0097056	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.4	0.4	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.4	1.6	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.4	2.0	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.4	1.6	GO:0046836	glycolipid transport(GO:0046836)
0.4	1.2	GO:0060166	olfactory pit development(GO:0060166)
0.4	1.6	GO:0042659	regulation of cell fate specification(GO:0042659)
0.4	1.2	GO:0071529	cementum mineralization(GO:0071529)
0.4	0.8	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.4	1.2	GO:0031076	embryonic camera-type eye development(GO:0031076)
0.4	1.6	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4	5.6	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.4	2.8	GO:0046485	ether lipid metabolic process(GO:0046485)
0.4	1.2	GO:0097503	sialylation(GO:0097503)
0.4	0.4	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.4	3.1	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4	0.8	GO:0001842	neural fold formation(GO:0001842)
0.4	2.3	GO:0048011	neurotrophin TRK receptor signaling pathway(GO:0048011)
0.4	8.6	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.4	1.2	GO:0002317	plasma cell differentiation(GO:0002317)
0.4	1.2	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.4	2.7	GO:0008218	bioluminescence(GO:0008218)
0.4	0.8	GO:0072104	glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.4	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.4	1.2	GO:0035878	nail development(GO:0035878)
0.4	1.9	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4	0.8	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.4	4.2	GO:0006621	protein retention in ER lumen(GO:0006621)
0.4	3.4	GO:0009629	response to gravity(GO:0009629)
0.4	0.8	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.4	1.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.4	0.4	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.4	1.1	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.4	4.1	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.4	1.9	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.4	4.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.4	1.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4	5.2	GO:0009650	UV protection(GO:0009650)
0.4	0.4	GO:0010507	negative regulation of autophagy(GO:0010507)
0.4	4.1	GO:0030043	actin filament fragmentation(GO:0030043)
0.4	0.7	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4	2.2	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.4	3.3	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.4	1.1	GO:0060838	lymphatic endothelial cell fate commitment(GO:0060838) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.4	5.1	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.4	4.7	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.4	0.4	GO:0060022	hard palate development(GO:0060022)
0.4	5.1	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.4	6.5	GO:0030199	collagen fibril organization(GO:0030199)
0.4	0.4	GO:0009182	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182)
0.4	2.1	GO:0070527	platelet aggregation(GO:0070527)
0.4	1.1	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.4	3.2	GO:0001946	lymphangiogenesis(GO:0001946)
0.4	3.5	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
0.4	1.8	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.4	1.1	GO:0007231	osmosensory signaling pathway(GO:0007231)
0.4	1.8	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.4	8.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.4	1.4	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.3	0.3	GO:0002663	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.3	1.0	GO:1905224	clathrin-coated pit assembly(GO:1905224)
0.3	1.4	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.3	15.2	GO:0006027	glycosaminoglycan catabolic process(GO:0006027)
0.3	0.7	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.3	1.4	GO:0044375	regulation of peroxisome size(GO:0044375)
0.3	3.7	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3	1.0	GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.3	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.3	1.4	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.3	1.4	GO:0032730	positive regulation of interleukin-1 alpha production(GO:0032730)
0.3	0.3	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.3	1.7	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3	2.3	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.3	1.7	GO:0060413	atrial septum morphogenesis(GO:0060413)
0.3	2.0	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.3	0.3	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.3	2.3	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3	2.3	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.3	0.3	GO:0060602	branch elongation of an epithelium(GO:0060602)
0.3	0.3	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.3	4.3	GO:0046069	cGMP catabolic process(GO:0046069)
0.3	0.3	GO:0051409	response to nitrosative stress(GO:0051409)
0.3	7.2	GO:0097178	ruffle assembly(GO:0097178)
0.3	3.9	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.3	2.3	GO:0031529	ruffle organization(GO:0031529)
0.3	1.6	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.3	5.4	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.3	3.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3	2.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.3	0.3	GO:0033604	negative regulation of catecholamine secretion(GO:0033604)
0.3	1.6	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.3	1.3	GO:0019046	release from viral latency(GO:0019046)
0.3	0.6	GO:0034214	protein hexamerization(GO:0034214)
0.3	2.8	GO:0060068	vagina development(GO:0060068)
0.3	1.6	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.3	2.2	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.3	0.6	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.3	3.4	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.3	3.4	GO:0032456	endocytic recycling(GO:0032456)
0.3	0.9	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.3	1.2	GO:0070459	prolactin secretion(GO:0070459)
0.3	0.9	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.3	0.9	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.3	2.7	GO:1903019	negative regulation of glycoprotein metabolic process(GO:1903019)
0.3	0.9	GO:0071695	anatomical structure maturation(GO:0071695)
0.3	2.1	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.3	1.8	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.3	1.2	GO:0044804	nucleophagy(GO:0044804)
0.3	0.9	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.3	0.6	GO:0034036	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3	0.3	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.3	0.3	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.3	0.6	GO:0030242	pexophagy(GO:0030242)
0.3	0.9	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.3	0.9	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3	1.2	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.3	2.6	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.3	11.2	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.3	1.2	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.3	1.4	GO:1902473	regulation of protein localization to synapse(GO:1902473)
0.3	0.6	GO:0021558	trochlear nerve development(GO:0021558)
0.3	1.1	GO:0048266	behavioral response to pain(GO:0048266)
0.3	0.6	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.3	0.3	GO:0090107	regulation of high-density lipoprotein particle assembly(GO:0090107)
0.3	0.9	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.3	0.9	GO:0019477	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.3	0.9	GO:0051697	protein delipidation(GO:0051697)
0.3	0.6	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.3	2.0	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.3	0.8	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3	3.1	GO:0035372	protein localization to microtubule(GO:0035372)
0.3	2.0	GO:0060352	cell adhesion molecule production(GO:0060352)
0.3	1.1	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3	3.3	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.3	1.9	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3	0.3	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.3	2.8	GO:1901621	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3	4.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.3	0.3	GO:1903020	positive regulation of glycoprotein metabolic process(GO:1903020)
0.3	0.3	GO:0032898	neurotrophin production(GO:0032898)
0.3	1.4	GO:0055064	chloride ion homeostasis(GO:0055064)
0.3	0.3	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.3	3.5	GO:0097062	dendritic spine maintenance(GO:0097062)
0.3	0.8	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.3	1.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.3	0.5	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.3	0.5	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.3	16.2	GO:1902017	regulation of cilium assembly(GO:1902017)
0.3	0.8	GO:0003299	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3	0.3	GO:0060023	soft palate development(GO:0060023)
0.3	0.8	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.3	0.3	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3	0.8	GO:0006097	glyoxylate cycle(GO:0006097)
0.3	0.8	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.3	2.1	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3	0.8	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.3	0.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.3	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3	4.0	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.3	0.5	GO:0071494	cellular response to UV-C(GO:0071494)
0.3	0.8	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3	0.8	GO:0007172	signal complex assembly(GO:0007172)
0.3	0.8	GO:0051412	response to corticosterone(GO:0051412)
0.3	2.6	GO:0036119	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.3	0.8	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3	0.5	GO:0090045	positive regulation of deacetylase activity(GO:0090045)
0.3	14.3	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.3	0.8	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.3	0.8	GO:0090324	negative regulation of oxidative phosphorylation(GO:0090324)
0.3	0.8	GO:0071493	cellular response to UV-B(GO:0071493)
0.3	2.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.3	0.8	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.3	1.8	GO:0001881	receptor recycling(GO:0001881)
0.3	2.6	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.3	13.1	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.3	0.5	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.3	1.3	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.3	1.5	GO:0071468	cellular response to acidic pH(GO:0071468)
0.3	2.3	GO:0090128	regulation of synapse maturation(GO:0090128)
0.3	0.8	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.3	0.3	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.3	2.0	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.3	4.3	GO:0044458	motile cilium assembly(GO:0044458)
0.3	0.5	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.3	2.3	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.3	0.3	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.2	0.7	GO:0061760	antifungal innate immune response(GO:0061760)
0.2	0.2	GO:1902218	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218)
0.2	1.2	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	0.2	GO:0060920	cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.2	1.7	GO:0045598	regulation of fat cell differentiation(GO:0045598)
0.2	1.7	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.2	1.7	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.2	1.7	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.2	1.7	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.2	2.9	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2	1.0	GO:0048505	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2	0.5	GO:0060281	regulation of oocyte development(GO:0060281)
0.2	2.9	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.2	2.9	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.2	2.2	GO:0060117	auditory receptor cell development(GO:0060117)
0.2	0.7	GO:0031017	exocrine pancreas development(GO:0031017)
0.2	0.7	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2	0.2	GO:0036215	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.2	1.9	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.2	0.5	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.2	0.5	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.2	0.7	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2	1.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.2	3.1	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.2	4.2	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.2	2.8	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.2	0.7	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.2	0.5	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2	1.2	GO:0019323	pentose catabolic process(GO:0019323)
0.2	0.7	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.2	0.5	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.2	0.7	GO:0031033	myosin filament organization(GO:0031033)
0.2	1.8	GO:0035493	SNARE complex assembly(GO:0035493)
0.2	12.0	GO:0030574	collagen catabolic process(GO:0030574)
0.2	0.5	GO:1990164	histone H2A phosphorylation(GO:1990164)
0.2	2.5	GO:0006855	drug transmembrane transport(GO:0006855)
0.2	0.9	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.2	1.1	GO:1904100	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2	1.6	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.2	0.7	GO:1901096	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.2	0.7	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2	1.6	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2	0.7	GO:0032275	luteinizing hormone secretion(GO:0032275)
0.2	0.5	GO:0034653	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.2	0.7	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.2	0.9	GO:0003016	respiratory system process(GO:0003016)
0.2	0.7	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.2	0.4	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.2	1.1	GO:0003420	growth plate cartilage chondrocyte proliferation(GO:0003419) regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.2	1.8	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.2	0.2	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.2	4.7	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.2	0.2	GO:0043578	nuclear matrix organization(GO:0043578)
0.2	0.9	GO:0007340	acrosome reaction(GO:0007340)
0.2	8.4	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.2	0.4	GO:0097091	synaptic vesicle clustering(GO:0097091)
0.2	0.4	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.2	0.7	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2	11.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.2	0.7	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.2	0.2	GO:0036514	dopaminergic neuron axon guidance(GO:0036514) planar cell polarity pathway involved in axon guidance(GO:1904938)
0.2	0.4	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.2	0.6	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.2	1.1	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.2	0.2	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.2	1.9	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.2	5.3	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2	2.1	GO:0006749	glutathione metabolic process(GO:0006749)
0.2	0.6	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2	3.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.2	0.4	GO:0080184	response to phenylpropanoid(GO:0080184)
0.2	1.2	GO:0051410	detoxification of nitrogen compound(GO:0051410)
0.2	0.4	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2	0.6	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2	0.8	GO:0042335	cuticle development(GO:0042335)
0.2	1.4	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
0.2	0.6	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2	0.2	GO:0090303	positive regulation of wound healing(GO:0090303)
0.2	1.4	GO:0035897	proteolysis in other organism(GO:0035897)
0.2	2.2	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.2	1.2	GO:0061635	regulation of protein complex stability(GO:0061635)
0.2	2.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.2	0.4	GO:2000178	negative regulation of neural precursor cell proliferation(GO:2000178)
0.2	1.0	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2	0.4	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.2	1.0	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.2	1.4	GO:0071709	membrane assembly(GO:0071709)
0.2	0.4	GO:1904434	regulation of T cell antigen processing and presentation(GO:0002625) regulation of iron ion transport(GO:0034756) positive regulation of iron ion transport(GO:0034758) regulation of iron ion transmembrane transport(GO:0034759) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.2	4.0	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2	2.6	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.2	5.9	GO:0008333	endosome to lysosome transport(GO:0008333)
0.2	0.6	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2	0.4	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.2	0.6	GO:0035915	pore formation in membrane of other organism(GO:0035915)
0.2	0.6	GO:0036511	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.2	0.6	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2	0.6	GO:0060444	branching involved in mammary gland duct morphogenesis(GO:0060444)
0.2	0.6	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.2	0.6	GO:0014735	regulation of muscle atrophy(GO:0014735) negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2	0.2	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.2	1.5	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.2	1.0	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.2	2.5	GO:0007368	determination of left/right symmetry(GO:0007368)
0.2	1.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.2	3.4	GO:0000042	protein targeting to Golgi(GO:0000042)
0.2	0.8	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.2	1.1	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.2	0.2	GO:0050932	regulation of pigment cell differentiation(GO:0050932)
0.2	0.8	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.2	0.9	GO:0001967	suckling behavior(GO:0001967)
0.2	0.6	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2	0.2	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.2	2.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.2	0.5	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.2	1.8	GO:0030323	respiratory tube development(GO:0030323)
0.2	0.4	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.2	0.7	GO:0040016	embryonic cleavage(GO:0040016)
0.2	10.0	GO:0046323	glucose import(GO:0046323)
0.2	0.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.2	1.4	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	0.2	GO:0086068	Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.2	1.9	GO:0007567	parturition(GO:0007567)
0.2	0.5	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2	0.5	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2	0.5	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.2	0.5	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.2	3.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.2	1.2	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.2	0.3	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
0.2	0.5	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2	0.5	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.2	0.9	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.2	2.7	GO:0019076	viral release from host cell(GO:0019076)
0.2	2.9	GO:0048286	lung alveolus development(GO:0048286)
0.2	1.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2	2.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	0.2	GO:2000466	negative regulation of glycogen (starch) synthase activity(GO:2000466)
0.2	0.3	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2	0.7	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2	0.5	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2	1.0	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.2	1.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.2	1.0	GO:0002911	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.2	0.3	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.2	1.5	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.2	2.6	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2	1.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.2	0.6	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.2	0.6	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.2	0.6	GO:0031642	negative regulation of myelination(GO:0031642)
0.2	0.5	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.2	1.4	GO:0006465	signal peptide processing(GO:0006465)
0.2	0.6	GO:0019249	lactate biosynthetic process(GO:0019249)
0.2	0.3	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
0.2	1.1	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.2	1.4	GO:0030091	protein repair(GO:0030091)
0.2	0.6	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.2	0.9	GO:0048854	brain morphogenesis(GO:0048854)
0.2	0.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.2	0.3	GO:0016264	gap junction assembly(GO:0016264)
0.2	0.9	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2	0.2	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.2	0.3	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2	4.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.2	0.2	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2	2.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.2	0.9	GO:0046465	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.2	2.1	GO:0010842	retina layer formation(GO:0010842)
0.2	0.3	GO:1902430	negative regulation of beta-amyloid formation(GO:1902430)
0.2	0.2	GO:0035723	interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.2	0.5	GO:0072249	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2	0.3	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1	1.3	GO:0032026	response to magnesium ion(GO:0032026)
0.1	2.4	GO:0061512	protein localization to cilium(GO:0061512)
0.1	0.6	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.1	0.4	GO:1902949	positive regulation of tau-protein kinase activity(GO:1902949)
0.1	0.4	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.7	GO:1903541	regulation of exosomal secretion(GO:1903541)
0.1	0.4	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
0.1	0.1	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.1	0.6	GO:0030278	regulation of ossification(GO:0030278)
0.1	1.2	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1	1.0	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1	0.9	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	1.3	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.1	3.3	GO:0016486	peptide hormone processing(GO:0016486)
0.1	1.9	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.7	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	0.3	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1	0.9	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1	1.4	GO:0048709	oligodendrocyte differentiation(GO:0048709)
0.1	0.1	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1	5.9	GO:0043171	peptide catabolic process(GO:0043171)
0.1	0.6	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.1	0.7	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1	0.1	GO:0021591	ventricular system development(GO:0021591)
0.1	0.6	GO:0001878	response to yeast(GO:0001878)
0.1	29.5	GO:0043062	extracellular structure organization(GO:0043062)
0.1	0.8	GO:0030728	ovulation(GO:0030728)
0.1	2.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.3	GO:0042360	vitamin E metabolic process(GO:0042360)
0.1	2.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.1	GO:1990502	dense core granule maturation(GO:1990502)
0.1	1.4	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1	0.1	GO:0019081	viral translation(GO:0019081)
0.1	0.3	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	0.7	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.1	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.1	0.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.1	GO:0060192	negative regulation of lipase activity(GO:0060192)
0.1	0.4	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1	0.5	GO:0046502	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.5	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.3	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	2.1	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1	1.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	1.7	GO:0048642	negative regulation of skeletal muscle tissue development(GO:0048642)
0.1	2.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.4	GO:1904046	protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1	0.3	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.1	1.3	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	0.3	GO:0001575	globoside metabolic process(GO:0001575)
0.1	0.5	GO:0048260	positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1	1.0	GO:0071625	vocalization behavior(GO:0071625)
0.1	1.9	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.1	0.6	GO:0009994	oocyte differentiation(GO:0009994)
0.1	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.1	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
0.1	1.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.1	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.1	0.9	GO:0042426	choline catabolic process(GO:0042426)
0.1	2.6	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.1	0.7	GO:0044065	regulation of respiratory system process(GO:0044065)
0.1	0.1	GO:0030860	regulation of polarized epithelial cell differentiation(GO:0030860)
0.1	1.4	GO:0006853	carnitine shuttle(GO:0006853)
0.1	2.9	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	1.2	GO:0008298	intracellular mRNA localization(GO:0008298)
0.1	0.5	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.1	0.1	GO:0032376	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.1	7.5	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.1	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.4	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	0.6	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	0.1	GO:0010644	cell communication by electrical coupling(GO:0010644)
0.1	0.6	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.5	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.1	0.2	GO:0033687	osteoblast proliferation(GO:0033687)
0.1	1.5	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.1	0.1	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1	0.1	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.1	17.0	GO:0007266	Rho protein signal transduction(GO:0007266)
0.1	0.5	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1	0.5	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.3	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.1	GO:0045763	negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1	0.9	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.1	0.8	GO:0090161	Golgi ribbon formation(GO:0090161)
0.1	0.8	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.6	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1	2.2	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.1	1.4	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.1	GO:0044788	modulation by host of viral process(GO:0044788)
0.1	0.1	GO:2000465	regulation of glycogen (starch) synthase activity(GO:2000465)
0.1	0.8	GO:0007530	sex determination(GO:0007530)
0.1	3.1	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	0.4	GO:0036337	Fas signaling pathway(GO:0036337)
0.1	1.2	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.4	GO:0060591	chondroblast differentiation(GO:0060591)
0.1	1.6	GO:0006828	manganese ion transport(GO:0006828)
0.1	1.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.1	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	0.3	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1	0.3	GO:0036159	inner dynein arm assembly(GO:0036159)
0.1	0.8	GO:0030539	male genitalia development(GO:0030539)
0.1	0.2	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.1	0.3	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.1	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.1	0.1	GO:0031128	developmental induction(GO:0031128)
0.1	0.9	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.1	0.2	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	2.2	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.1	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.2	GO:0002437	inflammatory response to antigenic stimulus(GO:0002437)
0.1	6.0	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	0.2	GO:0006738	nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638) pyridine-containing compound catabolic process(GO:0072526)
0.1	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.1	0.3	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1	3.9	GO:0030516	regulation of axon extension(GO:0030516)
0.1	2.4	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	0.2	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.6	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1	0.6	GO:0009642	response to light intensity(GO:0009642)
0.1	2.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.4	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.8	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	0.4	GO:0033216	copper ion import(GO:0015677) ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	0.4	GO:0048243	norepinephrine secretion(GO:0048243)
0.1	1.0	GO:0006818	hydrogen transport(GO:0006818) proton transport(GO:0015992)
0.1	0.3	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.1	GO:0052803	imidazole-containing compound metabolic process(GO:0052803)
0.1	0.2	GO:2000035	regulation of stem cell division(GO:2000035)
0.1	0.2	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.1	0.1	GO:0034091	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.1	0.2	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.1	0.6	GO:0072592	oxygen metabolic process(GO:0072592)
0.1	0.2	GO:0035729	cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.1	0.5	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1	1.0	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.1	0.6	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1	0.7	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.1	0.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.6	GO:0010919	regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1	0.5	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	0.2	GO:0048485	sympathetic nervous system development(GO:0048485)
0.1	0.1	GO:0071313	cellular response to caffeine(GO:0071313)
0.1	2.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.1	0.3	GO:0042509	regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1	0.2	GO:0070633	transepithelial transport(GO:0070633) transepithelial ammonium transport(GO:0070634)
0.1	1.8	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.5	GO:0036465	synaptic vesicle recycling(GO:0036465)
0.1	1.9	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.1	0.3	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.4	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	0.9	GO:0006939	smooth muscle contraction(GO:0006939)
0.1	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1	0.3	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1	0.5	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	1.3	GO:0097502	mannosylation(GO:0097502)
0.1	0.2	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1	0.3	GO:0070842	aggresome assembly(GO:0070842)
0.1	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1	0.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	0.2	GO:0061117	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of heart growth(GO:0061117)
0.1	0.9	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.1	0.3	GO:0035803	egg coat formation(GO:0035803)
0.1	0.1	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.1	0.3	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.1	0.3	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.1	0.2	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	0.8	GO:0007405	neuroblast proliferation(GO:0007405)
0.1	0.9	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.1	0.7	GO:0003351	epithelial cilium movement(GO:0003351)
0.1	4.9	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.1	1.1	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.1	0.7	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1	0.1	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.5	GO:0032060	bleb assembly(GO:0032060)
0.1	0.2	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.2	GO:0090175	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1	0.3	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.6	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.1	0.2	GO:0007632	visual behavior(GO:0007632)
0.1	0.5	GO:0045921	positive regulation of exocytosis(GO:0045921)
0.1	0.3	GO:2000811	negative regulation of anoikis(GO:2000811)
0.1	0.2	GO:0042160	plasma lipoprotein particle oxidation(GO:0034441) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.1	1.7	GO:0001578	microtubule bundle formation(GO:0001578)
0.1	0.3	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1	1.3	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1	0.4	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1	0.6	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	5.6	GO:0007160	cell-matrix adhesion(GO:0007160)
0.1	0.3	GO:0061436	establishment of skin barrier(GO:0061436)
0.1	0.3	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1	0.8	GO:0007220	Notch receptor processing(GO:0007220)
0.1	0.4	GO:0051775	response to redox state(GO:0051775)
0.1	0.4	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.1	0.2	GO:0016999	antibiotic metabolic process(GO:0016999)
0.1	3.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	0.5	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.1	0.9	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.2	GO:0060452	positive regulation of cardiac muscle contraction(GO:0060452)
0.1	0.1	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.1	1.5	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1	0.6	GO:0045974	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1	1.2	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.1	0.1	GO:0010713	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.1	0.1	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1	0.4	GO:0009268	response to pH(GO:0009268)
0.1	0.1	GO:0048102	autophagic cell death(GO:0048102)
0.1	1.9	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.2	GO:0072109	glomerular mesangium development(GO:0072109)
0.1	0.1	GO:0007113	endomitotic cell cycle(GO:0007113)
0.1	0.1	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664)
0.1	0.2	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.1	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.1	1.2	GO:0006458	'de novo' protein folding(GO:0006458)
0.1	0.4	GO:0006517	protein deglycosylation(GO:0006517)
0.1	0.7	GO:0070207	protein homotrimerization(GO:0070207)
0.1	0.1	GO:0021783	preganglionic parasympathetic fiber development(GO:0021783)
0.1	0.3	GO:0045188	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.1	0.1	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.1	0.2	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.1	0.2	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	0.1	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.1	0.7	GO:0051354	negative regulation of oxidoreductase activity(GO:0051354)
0.1	0.5	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.1	0.1	GO:0035524	proline transmembrane transport(GO:0035524)
0.1	0.8	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1	0.2	GO:0048710	regulation of astrocyte differentiation(GO:0048710)
0.1	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.3	GO:0035063	nuclear speck organization(GO:0035063)
0.1	0.7	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1	0.4	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035358)
0.1	0.1	GO:0006529	asparagine biosynthetic process(GO:0006529)
0.1	0.1	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1	1.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.1	GO:1902170	cellular response to reactive nitrogen species(GO:1902170)
0.1	0.3	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.1	0.3	GO:0006983	ER overload response(GO:0006983)
0.1	0.2	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1	0.4	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	1.7	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.3	GO:0003094	glomerular filtration(GO:0003094)
0.1	0.4	GO:0045023	G0 to G1 transition(GO:0045023)
0.1	0.2	GO:0071600	otic vesicle formation(GO:0030916) otic vesicle morphogenesis(GO:0071600)
0.1	0.1	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1	0.3	GO:0031112	positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.1	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.1	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.1	0.1	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
0.1	0.1	GO:0015874	norepinephrine transport(GO:0015874)
0.1	0.1	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.1	0.3	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.4	GO:0015705	iodide transport(GO:0015705)
0.1	0.1	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1	0.7	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1	0.3	GO:0003322	pancreatic A cell development(GO:0003322)
0.1	0.1	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.1	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.1	GO:0072033	renal vesicle formation(GO:0072033)
0.1	0.2	GO:1900426	positive regulation of defense response to bacterium(GO:1900426)
0.1	0.1	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.1	0.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.1	0.1	GO:0034394	protein localization to cell surface(GO:0034394)
0.1	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.7	GO:0061213	positive regulation of mesonephros development(GO:0061213)
0.0	0.3	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.0	GO:0002118	aggressive behavior(GO:0002118)
0.0	0.2	GO:1901906	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0	0.1	GO:0014866	skeletal myofibril assembly(GO:0014866) mesenchyme migration(GO:0090131)
0.0	0.4	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.1	GO:0001555	oocyte growth(GO:0001555)
0.0	0.1	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.0	0.4	GO:0060004	reflex(GO:0060004)
0.0	0.2	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0	0.5	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway(GO:0038094) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0	0.3	GO:0003416	endochondral bone growth(GO:0003416)
0.0	0.2	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	2.4	GO:0097485	neuron projection guidance(GO:0097485)
0.0	0.3	GO:0051194	positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.0	0.3	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.0	GO:0060384	innervation(GO:0060384)
0.0	0.3	GO:0060065	uterus development(GO:0060065)
0.0	0.7	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0036035	osteoclast development(GO:0036035)
0.0	1.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.9	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0031291	Ran protein signal transduction(GO:0031291)
0.0	1.1	GO:0015918	sterol transport(GO:0015918)
0.0	0.0	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.4	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.3	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.4	GO:0050982	detection of mechanical stimulus(GO:0050982)
0.0	0.2	GO:0007506	gonadal mesoderm development(GO:0007506)
0.0	0.1	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.3	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.2	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.3	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.5	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.6	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.3	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0	0.1	GO:0001172	transcription, RNA-templated(GO:0001172)
0.0	0.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:0048569	post-embryonic organ development(GO:0048569)
0.0	5.0	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:1903027	regulation of opsonization(GO:1903027)
0.0	0.2	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.9	GO:0044247	glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	0.2	GO:0002438	acute inflammatory response to antigenic stimulus(GO:0002438)
0.0	0.2	GO:0007512	adult heart development(GO:0007512)
0.0	0.0	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.0	0.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.2	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:0042308	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.0	0.1	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.3	GO:0006552	leucine catabolic process(GO:0006552)
0.0	1.7	GO:0048839	inner ear development(GO:0048839)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780) GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0	0.0	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.2	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.1	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.2	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.3	GO:0006636	unsaturated fatty acid biosynthetic process(GO:0006636)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.2	GO:0030449	regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0	0.1	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:1902490	regulation of sperm capacitation(GO:1902490)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0	0.1	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:0045047	protein targeting to ER(GO:0045047)
0.0	0.2	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.3	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.0	0.1	GO:0002778	antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.0	0.4	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.5	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.1	GO:0010044	response to aluminum ion(GO:0010044)
0.0	0.0	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.0	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.5	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.2	GO:0001941	postsynaptic membrane organization(GO:0001941)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.4	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	0.2	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.0	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.2	GO:0007041	lysosomal transport(GO:0007041)
0.0	0.4	GO:2001240	negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.2	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.0	0.1	GO:0097242	beta-amyloid clearance(GO:0097242)
0.0	0.0	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.0	GO:1901862	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0	0.0	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.0	0.2	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.2	GO:0050909	sensory perception of taste(GO:0050909)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	1.6	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.0	GO:0002276	basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0	0.1	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.0	GO:0046732	induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.0	0.1	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.0	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0045907	positive regulation of vasoconstriction(GO:0045907)
0.0	0.0	GO:0010935	regulation of macrophage cytokine production(GO:0010935)
0.0	0.1	GO:0090344	negative regulation of cell aging(GO:0090344)
0.0	0.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0000423	macromitophagy(GO:0000423) response to mitochondrial depolarisation(GO:0098780)
0.0	0.6	GO:0019730	antimicrobial humoral response(GO:0019730)
0.0	0.0	GO:2000819	regulation of nucleotide-excision repair(GO:2000819)
0.0	0.0	GO:0042369	vitamin D catabolic process(GO:0042369)
0.0	0.0	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.0	0.0	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.5	GO:0035036	sperm-egg recognition(GO:0035036)
0.0	0.1	GO:0002526	acute inflammatory response(GO:0002526)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.0	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.0	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0	0.0	GO:0045124	regulation of bone resorption(GO:0045124)
0.0	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.0	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.0	1.9	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0097050	type B pancreatic cell apoptotic process(GO:0097050)
0.0	0.0	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717) negative regulation of fatty acid metabolic process(GO:0045922)
0.0	0.0	GO:0030497	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.0	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.0	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101)
0.0	0.0	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:1990637	response to prolactin(GO:1990637)
0.0	0.1	GO:0014909	smooth muscle cell migration(GO:0014909)
0.0	0.0	GO:1903036	positive regulation of response to wounding(GO:1903036)
0.0	0.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4	1.2	GO:0044609	DBIRD complex(GO:0044609)
0.2	2.8	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1	0.6	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.9	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.1	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.0	2.4	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.7	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.6	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.3	GO:0036452	ESCRT complex(GO:0036452)
0.0	0.2	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	3.0	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	3.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2	15.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	0.8	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	2.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	1.0	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	1.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.9	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	0.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	0.7	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.0	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	2.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	2.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.7	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	1.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.9	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.5	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.7	9.9	GO:0032395	MHC class II receptor activity(GO:0032395)
0.5	6.6	GO:0050700	CARD domain binding(GO:0050700)
0.5	3.7	GO:0019863	IgE binding(GO:0019863)
0.4	2.6	GO:0046979	TAP2 binding(GO:0046979)
0.4	2.5	GO:0042296	ISG15 transferase activity(GO:0042296)
0.4	1.9	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.4	2.7	GO:0043208	glycosphingolipid binding(GO:0043208)
0.4	2.5	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.3	2.4	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.3	0.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.3	2.3	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.3	18.0	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.3	0.9	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3	2.9	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.3	1.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.3	0.5	GO:0019770	IgG receptor activity(GO:0019770)
0.3	2.6	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2	0.5	GO:0071949	FAD binding(GO:0071949)
0.2	0.7	GO:0017130	poly(C) RNA binding(GO:0017130)
0.2	0.7	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	5.3	GO:0042605	peptide antigen binding(GO:0042605)
0.2	0.7	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.2	1.4	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2	0.9	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.2	0.9	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.7	GO:0005148	prolactin receptor binding(GO:0005148)
0.2	0.9	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2	0.2	GO:0001851	complement component C3b binding(GO:0001851)
0.2	2.2	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.2	0.6	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.2	1.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2	0.6	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.2	0.7	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.2	5.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.2	0.3	GO:0072510	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2	2.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	0.5	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	1.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.2	1.4	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.2	2.5	GO:0031996	thioesterase binding(GO:0031996)
0.2	1.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.2	0.5	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.2	0.5	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.2	0.6	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2	1.5	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.4	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.1	0.6	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1	0.6	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	0.4	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.6	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.1	0.6	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.6	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	1.3	GO:0045545	syndecan binding(GO:0045545)
0.1	0.7	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.3	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.1	0.4	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.4	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	0.4	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.4	GO:0004947	bradykinin receptor activity(GO:0004947)
0.1	0.9	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.1	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.1	2.0	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.6	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	0.3	GO:0032090	Pyrin domain binding(GO:0032090)
0.1	3.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.9	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	1.0	GO:0032393	MHC class I receptor activity(GO:0032393)
0.1	0.4	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.1	0.7	GO:0043532	angiostatin binding(GO:0043532)
0.1	1.8	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.6	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	1.2	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.1	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.1	1.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.3	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1	0.3	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.1	0.7	GO:0001515	opioid peptide activity(GO:0001515)
0.1	2.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.5	GO:0047820	D-glutamate cyclase activity(GO:0047820)
0.1	0.7	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.8	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	14.8	GO:0003823	antigen binding(GO:0003823)
0.1	0.3	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	8.5	GO:0005518	collagen binding(GO:0005518)
0.1	0.5	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.1	0.3	GO:0008859	exoribonuclease II activity(GO:0008859)
0.1	0.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	1.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.3	GO:0051748	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1	4.1	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.7	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	1.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	4.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.5	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	0.3	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1	0.5	GO:1990254	keratin filament binding(GO:1990254)
0.1	1.4	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	2.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	1.8	GO:0051400	BH domain binding(GO:0051400)
0.1	0.5	GO:0036122	BMP binding(GO:0036122)
0.1	0.4	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.1	0.3	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.1	0.3	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.4	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.3	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1	1.9	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.3	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.3	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.1	0.2	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.6	GO:0016015	morphogen activity(GO:0016015)
0.1	0.2	GO:0005497	androgen binding(GO:0005497)
0.1	0.5	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	0.4	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	1.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.4	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	0.2	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	0.7	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	0.2	GO:0097001	ceramide binding(GO:0097001)
0.1	0.3	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.3	GO:0032408	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1	1.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.2	GO:0017129	triglyceride binding(GO:0017129)
0.1	0.3	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.2	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	0.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.2	GO:0097677	STAT family protein binding(GO:0097677)
0.1	0.2	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.1	0.2	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.1	0.3	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.1	GO:0002134	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1	0.2	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.1	1.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	0.4	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1	0.9	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.1	2.9	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.1	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	0.4	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	1.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.2	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1	0.3	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.3	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.1	0.8	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	1.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.4	GO:0032407	MutSalpha complex binding(GO:0032407)
0.1	0.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.7	GO:0003696	satellite DNA binding(GO:0003696)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.7	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.4	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.2	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	0.6	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.3	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	1.8	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.5	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.4	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.2	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.3	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.1	0.4	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.1	0.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	0.5	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.2	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.1	0.6	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.4	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1	0.4	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	1.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.4	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	0.3	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.2	GO:0015265	urea channel activity(GO:0015265)
0.1	0.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.5	GO:0005534	galactose binding(GO:0005534)
0.1	1.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.3	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.2	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.1	0.3	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.7	GO:0043047	single-stranded telomeric DNA binding(GO:0043047)
0.1	0.3	GO:0031432	titin binding(GO:0031432)
0.1	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.2	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.1	0.3	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	0.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.3	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1	0.2	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	1.3	GO:0031489	myosin V binding(GO:0031489)
0.1	0.3	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	0.2	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	1.2	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1	0.1	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0	0.1	GO:0042610	CD8 receptor binding(GO:0042610)
0.0	0.8	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.6	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.0	0.2	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.1	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.0	0.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.0	0.2	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	1.5	GO:0005109	frizzled binding(GO:0005109)
0.0	0.5	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.3	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.8	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.5	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.8	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.2	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.3	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.2	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.2	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	1.9	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.3	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0035326	enhancer binding(GO:0035326)
0.0	0.4	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	0.1	GO:1901476	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0	0.1	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0	1.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.4	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.2	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0	0.6	GO:0019841	retinol binding(GO:0019841)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0	0.3	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.0	0.3	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0035673	oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	0.5	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0016160	amylase activity(GO:0016160)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.4	GO:0070628	proteasome binding(GO:0070628)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.5	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.1	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	2.9	GO:0035004	phosphatidylinositol 3-kinase activity(GO:0035004)
0.0	0.4	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.0	GO:0016880	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0	0.5	GO:0043295	glutathione binding(GO:0043295)
0.0	0.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.4	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:1903136	cuprous ion binding(GO:1903136)
0.0	0.2	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.2	GO:0005119	smoothened binding(GO:0005119)
0.0	0.4	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.0	0.1	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
0.0	0.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.3	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.4	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.3	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.0	0.1	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.6	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	1.1	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.3	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.5	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.2	GO:0052739	phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0	0.6	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0031208	POZ domain binding(GO:0031208)
0.0	0.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0	0.3	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.5	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.1	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.2	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0	0.1	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.1	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0099583	postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0	0.4	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.2	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	1.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.7	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.5	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.0	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.3	GO:0016594	glycine binding(GO:0016594)
0.0	0.1	GO:0004348	glucosylceramidase activity(GO:0004348)
0.0	0.2	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.1	GO:0004882	androgen receptor activity(GO:0004882)
0.0	0.1	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
0.0	0.1	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	1.0	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.3	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0016295	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0	0.1	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0	10.3	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	0.0	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	0.1	GO:0019843	rRNA binding(GO:0019843)
0.0	0.3	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.4	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	1.0	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.0	0.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.0	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0	0.0	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.0	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0	0.4	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.3	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.0	0.4	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0	0.3	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.1	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	2.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.3	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.0	0.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0016979	lipoate-protein ligase activity(GO:0016979)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.3	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.1	GO:0019956	chemokine binding(GO:0019956)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.4	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.1	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.0	0.0	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.0	GO:0016730	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0	0.2	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.1	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.0	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	5.8	GO:0005525	GTP binding(GO:0005525)
0.0	0.0	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.0	0.9	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0004766	spermidine synthase activity(GO:0004766)
0.0	0.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.0	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.1	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.0	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.0	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0004137	deoxycytidine kinase activity(GO:0004137)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.0	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.2	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.0	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0	0.1	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0	0.1	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.0	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.0	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.0	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.0	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.0	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0034061	DNA polymerase activity(GO:0034061)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.0	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.0	GO:0009975	cyclase activity(GO:0009975)
0.0	0.1	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.5	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.0	0.1	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.0	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.5	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.0	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	0.7	GO:0000149	SNARE binding(GO:0000149)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0052594	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2	1.4	GO:0071253	connexin binding(GO:0071253)
0.2	1.0	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.3	GO:1902122	chenodeoxycholic acid binding(GO:1902122)
0.1	0.6	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	0.8	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	1.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.6	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.3	GO:0005329	dopamine transmembrane transporter activity(GO:0005329) quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	1.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	1.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.6	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.5	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.6	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.3	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.2	GO:0000150	recombinase activity(GO:0000150)
0.0	0.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.7	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.9	4.4	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.8	2.4	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.7	2.1	GO:0002522	leukocyte migration involved in immune response(GO:0002522)
0.7	2.0	GO:0061010	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.6	3.1	GO:1902896	terminal web assembly(GO:1902896)
0.6	1.8	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6	3.0	GO:0001315	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.6	2.4	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.6	2.3	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5	1.6	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.5	1.6	GO:0060621	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.5	1.4	GO:2000525	dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.4	1.8	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4	1.3	GO:0043132	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.4	1.3	GO:1902994	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.4	2.0	GO:0061107	seminal vesicle development(GO:0061107)
0.4	2.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.4	1.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.4	1.5	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.4	2.2	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.4	1.1	GO:1902023	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.3	1.4	GO:0014028	notochord formation(GO:0014028)
0.3	1.7	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3	1.6	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3	1.3	GO:0016139	glycoside catabolic process(GO:0016139)
0.3	0.9	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3	3.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.3	1.5	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.3	2.1	GO:1904925	negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3	0.6	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.3	1.5	GO:0032571	response to vitamin K(GO:0032571)
0.3	1.7	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.3	1.4	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.3	0.8	GO:1904647	response to rotenone(GO:1904647)
0.3	0.8	GO:0072709	cellular response to sorbitol(GO:0072709)
0.3	1.3	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.3	0.8	GO:1902771	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3	1.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3	1.3	GO:1903412	response to bile acid(GO:1903412)
0.3	1.0	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.3	2.5	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.3	0.8	GO:0003285	septum secundum development(GO:0003285)
0.2	0.7	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2	1.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	0.7	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.2	0.9	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.2	2.2	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.2	0.7	GO:1901355	response to rapamycin(GO:1901355)
0.2	1.1	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.2	0.7	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2	0.9	GO:0071461	cellular response to redox state(GO:0071461)
0.2	0.9	GO:1904379	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2	2.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	0.6	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.2	1.2	GO:0070560	protein secretion by platelet(GO:0070560)
0.2	1.0	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.2	4.8	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2	0.8	GO:0048859	formation of anatomical boundary(GO:0048859)
0.2	0.6	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2	0.6	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2	0.6	GO:1903939	negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.2	0.8	GO:0035426	extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304)
0.2	1.0	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	0.2	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115)
0.2	0.4	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.2	0.5	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2	0.9	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
0.2	1.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2	0.5	GO:0045082	interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2	0.5	GO:0016095	polyprenol catabolic process(GO:0016095)
0.2	1.0	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2	1.0	GO:1903416	response to glycoside(GO:1903416)
0.2	0.7	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.2	0.5	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2	0.3	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2	0.5	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.2	0.5	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.2	1.2	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.2	1.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.5	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2	0.5	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.2	0.6	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	0.5	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.2	4.2	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2	1.5	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.6	GO:0022614	membrane to membrane docking(GO:0022614) establishment of Sertoli cell barrier(GO:0097368)
0.1	0.3	GO:1904468	negative regulation of tumor necrosis factor secretion(GO:1904468)
0.1	2.4	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1	2.7	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.4	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.4	GO:0043449	cellular alkene metabolic process(GO:0043449)
0.1	0.6	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1	1.0	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.1	1.0	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.1	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.1	0.4	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.1	1.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	2.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	2.7	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.3	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	0.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	2.2	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.1	3.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	0.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.9	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.1	0.4	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1	2.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	2.3	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	1.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	0.4	GO:0097254	renal tubular secretion(GO:0097254)
0.1	0.6	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1	0.4	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1	3.1	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	0.2	GO:0019827	stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.1	0.4	GO:0032292	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.4	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.4	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.1	0.4	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	0.3	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.1	0.7	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.8	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.1	0.5	GO:0051958	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1	2.4	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	0.5	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.1	0.3	GO:1990519	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1	0.6	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.4	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	2.6	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.3	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.1	0.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	7.4	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	1.1	GO:0070673	response to interleukin-18(GO:0070673)
0.1	1.5	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1	0.3	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.6	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.9	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.5	GO:0036100	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1	0.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.6	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1	0.2	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904) regulation of pro-B cell differentiation(GO:2000973)
0.1	0.2	GO:0003383	apical constriction(GO:0003383)
0.1	0.5	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.6	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.1	0.7	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.4	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1	0.6	GO:0030421	defecation(GO:0030421)
0.1	0.4	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	0.2	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.1	0.7	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.4	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	0.7	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.8	GO:0071313	cellular response to caffeine(GO:0071313)
0.1	0.6	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	1.0	GO:0007422	peripheral nervous system development(GO:0007422)
0.1	0.3	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.2	GO:0090135	actin filament branching(GO:0090135)
0.1	0.9	GO:0033198	response to ATP(GO:0033198)
0.1	0.3	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1	0.8	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.4	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.3	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.3	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.1	1.2	GO:0033623	regulation of integrin activation(GO:0033623)
0.1	0.5	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.1	0.6	GO:0071315	cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.1	0.3	GO:1904303	positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) positive regulation of leukocyte tethering or rolling(GO:1903238) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1	1.1	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.1	5.5	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	0.3	GO:1904693	midbrain morphogenesis(GO:1904693)
0.1	0.3	GO:0010585	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1	1.6	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.3	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	0.3	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	1.4	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.1	0.3	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.1	1.3	GO:0032875	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.1	0.3	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.1	0.2	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.1	0.7	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.3	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.1	0.2	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1	0.5	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.1	0.7	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.4	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.6	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	1.3	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	0.2	GO:0051899	membrane depolarization(GO:0051899)
0.1	0.3	GO:0042126	nitrate metabolic process(GO:0042126)
0.1	0.4	GO:0048599	oocyte development(GO:0048599)
0.1	0.7	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1	0.9	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	1.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	0.2	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1	1.0	GO:0016180	snRNA processing(GO:0016180)
0.1	0.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.6	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.5	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	1.6	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.1	0.2	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.9	GO:0072520	seminiferous tubule development(GO:0072520)
0.1	4.1	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	1.4	GO:0071420	cellular response to histamine(GO:0071420)
0.1	1.5	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	1.0	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1	3.0	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.1	0.3	GO:0035711	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426) regulation of nucleotide-excision repair(GO:2000819)
0.1	0.3	GO:0050711	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 secretion(GO:0050711) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1	0.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.7	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.5	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.1	0.5	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.4	GO:1905031	regulation of potassium ion export(GO:1902302) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
0.1	0.5	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.8	GO:0043102	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.1	0.3	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.4	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.1	0.5	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.3	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:1990637	response to prolactin(GO:1990637)
0.1	0.4	GO:1990774	tumor necrosis factor secretion(GO:1990774)
0.1	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	1.4	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.9	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.2	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.2	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.2	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.1	0.4	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.4	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.1	0.4	GO:0033504	floor plate development(GO:0033504)
0.1	0.6	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.2	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1	0.3	GO:0048852	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.1	1.0	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.3	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.5	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	0.8	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1	0.3	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1	1.2	GO:0051923	sulfation(GO:0051923)
0.1	0.6	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1	0.5	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1	0.2	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1	1.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.4	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	0.5	GO:0006999	nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292)
0.1	0.9	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.1	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.2	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.1	0.4	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.6	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.2	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1	0.4	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.5	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.4	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1	0.9	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	1.3	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.1	0.2	GO:0008300	isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.5	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0050951	detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.0	0.3	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.3	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.4	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.1	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.0	0.5	GO:0015871	choline transport(GO:0015871)
0.0	0.9	GO:0006584	catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0	1.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.6	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.0	0.1	GO:0060844	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0	0.3	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.4	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0051167	xylulose metabolic process(GO:0005997) glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.2	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.6	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.2	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	1.8	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.6	GO:1903358	regulation of Golgi organization(GO:1903358)
0.0	0.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.4	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.0	0.3	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.0	0.5	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	1.0	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.7	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.2	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0006711	estrogen catabolic process(GO:0006711)
0.0	0.3	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.2	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.3	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	1.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.5	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.0	0.2	GO:0090278	negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0	1.6	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.0	0.1	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.0	0.6	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0	0.2	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.4	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.2	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	1.2	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.9	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.9	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.3	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.1	GO:0044268	angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.6	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.2	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0	0.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.3	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.0	0.6	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.0	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.0	0.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.0	0.6	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
0.0	0.2	GO:0046520	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0	0.4	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.0	0.1	GO:0002188	formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0	0.2	GO:0015692	lead ion transport(GO:0015692)
0.0	0.9	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.2	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.2	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.3	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.3	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.2	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.2	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.2	GO:2000254	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.9	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.3	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0	0.3	GO:0035247	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.3	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.7	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.4	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.2	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.4	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.3	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	0.8	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.4	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.1	GO:0019417	sulfur oxidation(GO:0019417)
0.0	0.4	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.7	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.3	GO:0033622	integrin activation(GO:0033622)
0.0	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0050893	sensory processing(GO:0050893)
0.0	0.0	GO:0070243	regulation of thymocyte apoptotic process(GO:0070243)
0.0	0.7	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.4	GO:0045475	locomotor rhythm(GO:0045475)
0.0	1.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.4	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	2.3	GO:0006334	nucleosome assembly(GO:0006334)
0.0	1.7	GO:0007602	phototransduction(GO:0007602)
0.0	0.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.7	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.6	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.3	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.5	GO:0097186	amelogenesis(GO:0097186)
0.0	0.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	1.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.4	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.2	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0	0.1	GO:0060423	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.1	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.5	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.2	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.8	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.0	GO:1903826	arginine transmembrane transport(GO:1903826)
0.0	1.8	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.3	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.4	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.2	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.3	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.1	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0071027	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.3	GO:0022401	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0	0.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.1	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.3	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.2	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.1	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.1	GO:0044070	regulation of anion transport(GO:0044070)
0.0	1.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	1.6	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0030279	negative regulation of ossification(GO:0030279)
0.0	0.3	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	0.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.4	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.2	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.4	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.2	GO:0097369	sodium ion import(GO:0097369)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:2001225	regulation of chloride transport(GO:2001225)
0.0	1.1	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.1	GO:1902416	regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416) regulation of RNA binding(GO:1905214) positive regulation of RNA binding(GO:1905216)
0.0	0.2	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.2	GO:0051321	meiotic cell cycle(GO:0051321)
0.0	0.2	GO:0071353	response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0	0.2	GO:0050728	negative regulation of inflammatory response(GO:0050728)
0.0	0.6	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.6	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0048290	isotype switching to IgA isotypes(GO:0048290)
0.0	0.3	GO:0016236	macroautophagy(GO:0016236)
0.0	0.2	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.7	GO:0006953	acute-phase response(GO:0006953)
0.0	0.5	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.4	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.5	GO:0051225	spindle assembly(GO:0051225)
0.0	0.5	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.2	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0006740	NADPH regeneration(GO:0006740)
0.0	1.0	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.1	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.6	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0	0.3	GO:0060711	labyrinthine layer development(GO:0060711)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	1.0	GO:0007286	spermatid development(GO:0007286)
0.0	0.4	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.3	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.2	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.6	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.6	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.1	GO:0045143	homologous chromosome segregation(GO:0045143)
0.0	1.5	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.7	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.2	GO:0009948	anterior/posterior axis specification(GO:0009948)
0.0	0.0	GO:0099624	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0	0.5	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.3	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.4	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.3	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.1	GO:0051591	response to cAMP(GO:0051591)
0.0	0.2	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0072503	cellular divalent inorganic cation homeostasis(GO:0072503) divalent inorganic cation homeostasis(GO:0072507)
0.0	0.0	GO:0098905	regulation of bundle of His cell action potential(GO:0098905) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.0	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.0	0.1	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2	0.5	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	1.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	1.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	1.7	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	1.5	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1	0.2	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.3	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.4	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	1.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.5	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.4	GO:0051183	vitamin transporter activity(GO:0051183)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.4	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	1.0	GO:0034464	BBSome(GO:0034464)
0.1	1.5	GO:0005687	U4 snRNP(GO:0005687)
0.1	1.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.6	GO:0036021	endolysosome lumen(GO:0036021)
0.1	1.4	GO:0097342	ripoptosome(GO:0097342)
0.1	0.4	GO:0042643	actomyosin, actin portion(GO:0042643)
0.1	1.3	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.9	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.8	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.9	GO:0005916	fascia adherens(GO:0005916)
0.1	0.2	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.7	GO:0030478	actin cap(GO:0030478)
0.0	0.3	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	2.5	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.2	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.3	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.0	0.6	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.3	GO:0032009	early phagosome(GO:0032009)
0.0	0.3	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0097227	sperm annulus(GO:0097227)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	0.1	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	1.3	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0014802	terminal cisterna(GO:0014802)
0.0	0.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.8	GO:0030286	dynein complex(GO:0030286)
0.0	0.3	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	2.5	GO:0043197	dendritic spine(GO:0043197)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	1.8	GO:0031901	early endosome membrane(GO:0031901)
0.0	1.6	GO:0043202	lysosomal lumen(GO:0043202)
0.0	1.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.4	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.3	GO:0043218	compact myelin(GO:0043218)
0.0	0.3	GO:0030673	axolemma(GO:0030673)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	1.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.2	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	0.1	GO:0070195	growth hormone receptor complex(GO:0070195)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	3.8	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	2.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	7.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.2	3.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2	1.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	3.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	4.3	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1	4.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	4.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	1.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	1.1	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	1.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	2.0	REACTOME KINESINS	Genes involved in Kinesins
0.1	2.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.8	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	5.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	3.9	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	0.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	0.7	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	0.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	0.7	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	7.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	1.0	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	3.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	2.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	2.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	1.0	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.8	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.7	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.9	PID ARF 3PATHWAY	Arf1 pathway
0.3	9.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3	3.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	7.6	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	1.8	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.3	8.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	9.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.2	8.3	PID MYC PATHWAY	C-MYC pathway
0.1	1.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	2.9	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	4.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	3.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	2.1	PID AURORA A PATHWAY	Aurora A signaling
0.1	1.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	4.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	1.9	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	6.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	5.0	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	5.4	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	3.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	4.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	1.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	1.7	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	2.5	PID INSULIN PATHWAY	Insulin Pathway
0.1	1.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	3.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	3.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	5.0	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	0.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	2.4	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.1	1.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	2.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	1.9	PID ALK1 PATHWAY	ALK1 signaling events
0.1	1.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	3.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	0.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	4.9	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	0.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	3.7	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	2.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.1	PID BARD1 PATHWAY	BARD1 signaling events
0.0	2.3	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.8	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	2.1	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.6	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	9.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.2	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.5	PID E2F PATHWAY	E2F transcription factor network
0.0	0.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.5	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	1.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.4	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	1.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	2.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.4	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.5	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.0	0.9	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	1.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	1.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
1.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.3	REACTOME KINESINS	Genes involved in Kinesins
0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	9.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.5	5.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	4.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	4.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	3.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	2.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	3.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	8.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	1.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	5.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.7	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	1.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.1	1.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	3.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	23.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	8.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	5.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	5.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	3.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	3.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	3.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	1.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	0.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	5.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	0.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	0.6	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	2.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.9	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.0	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	1.1	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.9	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	1.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.9	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.8	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	1.3	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.6	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
2.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
2.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.5	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
2.4	PID AURORA A PATHWAY	Aurora A signaling
0.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
1.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.5	PID IL5 PATHWAY	IL5-mediated signaling events
0.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
1.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
2.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	PID EPO PATHWAY	EPO signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	4.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.1	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.3	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	1.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	1.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME G1 PHASE	Genes involved in G1 Phase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	32.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
1.0	5.9	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.9	39.3	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.9	2.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.9	7.8	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.8	1.6	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.8	28.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.7	6.9	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.7	8.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.6	9.7	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.6	19.4	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.6	4.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.5	12.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.5	0.5	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.5	2.0	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.5	1.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5	10.8	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.4	5.8	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.4	27.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.4	10.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.4	2.0	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4	10.3	REACTOME KINESINS	Genes involved in Kinesins
0.4	14.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.4	11.3	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.4	7.1	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.3	9.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.3	4.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.3	24.4	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.3	7.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.3	18.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	2.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.3	9.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	27.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3	7.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.3	27.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.3	22.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.3	8.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.3	12.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.3	0.9	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.3	10.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.3	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.3	28.9	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.3	1.1	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.3	4.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.3	5.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.3	1.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.3	5.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.3	5.8	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	4.2	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.3	8.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.3	9.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.3	4.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	4.3	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2	2.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	3.9	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2	4.7	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.2	7.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.2	4.8	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2	9.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	3.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.2	13.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.2	2.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.2	4.8	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.2	6.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2	19.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.2	4.7	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.2	4.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2	0.4	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.2	5.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.2	1.8	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	3.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	6.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	2.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.2	6.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	2.2	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.2	7.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	0.5	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.2	0.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	4.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	4.5	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	3.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	1.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	2.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	0.8	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	2.2	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.1	3.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.8	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	8.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	1.8	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	17.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	0.3	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.1	2.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	4.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.6	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	3.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	5.4	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	2.3	REACTOME TRANSCRIPTION	Genes involved in Transcription
0.1	3.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.8	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	2.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.4	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.1	0.3	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	1.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.7	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	1.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	13.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	0.2	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.1	0.8	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	1.0	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.1	2.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	0.1	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.1	1.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	2.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	10.5	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.1	2.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	3.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	17.9	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.1	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	0.6	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.0	0.1	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.0	0.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	1.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.7	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.7	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.1	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.5	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.8	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.3	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	3.5	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.6	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	3.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	0.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	1.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	1.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.8	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	1.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.8	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.3	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	0.2	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
0.1	0.2	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.3	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.4	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.7	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.7	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.4	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	1.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.7	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.0	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.0	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	2.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.6	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.3	0.8	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2	1.5	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	0.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.2	1.2	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.6	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	2.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.8	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	0.4	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	1.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.1	0.9	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	0.6	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.3	GO:0070728	leucine binding(GO:0070728)
0.1	0.2	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.4	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	1.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.0	0.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0004603	phenylethanolamine N-methyltransferase activity(GO:0004603)
0.0	0.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	1.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	1.0	GO:0019863	IgE binding(GO:0019863)
0.1	0.9	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.7	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.4	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	0.6	GO:0046979	TAP2 binding(GO:0046979)
0.1	0.2	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.1	3.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	0.5	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0	0.4	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.4	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.2	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.0	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	1.2	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.5	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0051373	telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0	1.9	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.0	0.1	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0	0.2	GO:0042731	PH domain binding(GO:0042731)
0.0	0.7	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.3	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.2	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.6	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.2	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.0	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.2	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0097157	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) pre-mRNA intronic binding(GO:0097157)
0.0	0.4	GO:0070577	lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.9	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.6	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	5.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.8	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.9	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	1.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.6	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.5	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	1.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	23.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7	27.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.7	42.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	6.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.6	5.7	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.5	33.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.5	16.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.5	9.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5	1.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4	21.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.4	14.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	0.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.4	8.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	9.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.4	7.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.4	1.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.4	9.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.4	4.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.3	6.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	6.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3	8.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	1.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	6.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.3	5.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	3.5	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.3	5.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.3	6.7	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.3	35.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	7.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	5.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	1.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	3.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	1.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	3.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	5.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	2.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	1.9	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2	2.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.2	4.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.2	8.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	1.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	5.4	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.2	4.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	3.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	2.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	2.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	2.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	7.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2	3.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	4.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	2.6	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	2.5	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.2	2.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	3.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	2.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	13.4	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	1.8	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	3.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.9	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	15.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	10.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	0.8	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1	3.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.4	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	2.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	3.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	3.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	1.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	6.2	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	3.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	0.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	7.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	1.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	1.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	5.2	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1	2.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	3.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	2.1	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	0.5	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.1	1.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	1.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.9	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	0.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	0.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	0.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	1.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	2.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	0.6	REACTOME OPSINS	Genes involved in Opsins
0.1	1.5	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.1	1.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.8	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	1.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	2.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	1.1	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.5	GO:1904379	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.9	3.5	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.7	4.0	GO:0001692	histamine metabolic process(GO:0001692)
0.6	1.7	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.5	1.9	GO:0042509	tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.4	1.2	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4	1.6	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.3	1.4	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.3	1.0	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3	1.0	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3	1.0	GO:0070428	negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.3	1.2	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.2	0.7	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2	1.2	GO:0030047	actin modification(GO:0030047)
0.2	0.9	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2	0.7	GO:0051697	protein delipidation(GO:0051697)
0.2	1.8	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	1.8	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2	0.7	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.2	1.1	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.2	0.6	GO:0006711	estrogen catabolic process(GO:0006711)
0.2	1.1	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.2	0.2	GO:0051683	establishment of Golgi localization(GO:0051683)
0.2	0.2	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.2	1.1	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2	0.6	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2	0.2	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.2	1.2	GO:0030421	defecation(GO:0030421)
0.2	0.6	GO:1900195	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.2	1.0	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.2	0.7	GO:0021564	vagus nerve development(GO:0021564)
0.2	1.9	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.2	0.7	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2	0.2	GO:0032607	interferon-alpha production(GO:0032607)
0.2	0.5	GO:0006014	D-ribose metabolic process(GO:0006014)
0.2	0.5	GO:0002752	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2	0.5	GO:0050748	negative regulation of lipoprotein metabolic process(GO:0050748)
0.2	0.5	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.2	0.5	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.2	0.6	GO:2000230	negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2	0.3	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.2	0.5	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1	0.7	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.4	GO:1903570	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1	1.8	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.1	0.4	GO:1900081	regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1	0.4	GO:1902365	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1	0.4	GO:0018283	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1	0.3	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1	0.1	GO:0002467	germinal center formation(GO:0002467)
0.1	3.5	GO:0043101	purine-containing compound salvage(GO:0043101)
0.1	0.4	GO:0048611	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1	0.8	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.8	GO:0015677	copper ion import(GO:0015677)
0.1	0.6	GO:0080009	mRNA methylation(GO:0080009)
0.1	0.4	GO:0003285	septum secundum development(GO:0003285)
0.1	0.5	GO:0002880	chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1	0.5	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.1	0.4	GO:0072092	ureteric bud invasion(GO:0072092)
0.1	0.1	GO:0014029	neural crest formation(GO:0014029)
0.1	0.5	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	0.4	GO:0070086	ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1	0.3	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) circadian temperature homeostasis(GO:0060086)
0.1	0.6	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.1	1.6	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.3	GO:0002590	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1	0.4	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.1	1.7	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	0.2	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.1	0.4	GO:0006114	glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.1	0.9	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.9	GO:0003096	renal sodium ion transport(GO:0003096)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	1.0	GO:0070836	caveola assembly(GO:0070836)
0.1	0.2	GO:0036344	platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1	0.9	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.1	0.9	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.4	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1	0.8	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1	0.5	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1	0.7	GO:0023035	CD40 signaling pathway(GO:0023035)
0.1	0.8	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.1	0.4	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1	0.3	GO:2000439	positive regulation of monocyte extravasation(GO:2000439)
0.1	1.2	GO:0046415	urate metabolic process(GO:0046415)
0.1	0.4	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	0.4	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.1	0.8	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	0.3	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1	0.4	GO:0051941	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1	0.4	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1	0.3	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	0.3	GO:0044375	regulation of peroxisome size(GO:0044375)
0.1	0.2	GO:0002456	T cell mediated immunity(GO:0002456)
0.1	0.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.9	GO:0002934	desmosome organization(GO:0002934)
0.1	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.6	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	1.5	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1	0.3	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.3	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1	0.3	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	0.4	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.1	0.1	GO:0031344	regulation of cell projection organization(GO:0031344)
0.1	0.3	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.6	GO:0071649	regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1	0.4	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1	0.2	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.2	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1	0.2	GO:0019323	pentose catabolic process(GO:0019323)
0.1	0.5	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	1.1	GO:0031167	rRNA methylation(GO:0031167)
0.1	0.3	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.3	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.6	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.3	GO:1902378	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1	0.3	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.3	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.1	0.1	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1	0.2	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1	0.2	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.1	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	1.4	GO:0033622	integrin activation(GO:0033622)
0.1	0.2	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.1	0.7	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1	0.2	GO:0098904	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652) regulation of AV node cell action potential(GO:0098904) regulation of bundle of His cell action potential(GO:0098905)
0.1	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.2	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.3	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164)
0.1	0.2	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.1	0.6	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.7	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.3	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.1	0.5	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	0.8	GO:1902222	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.2	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.1	0.3	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
0.1	0.8	GO:0070831	basement membrane assembly(GO:0070831)
0.1	0.2	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.2	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.2	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.2	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0	0.4	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.0	0.2	GO:0003322	pancreatic A cell development(GO:0003322)
0.0	0.4	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.3	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.0	0.5	GO:0038092	nodal signaling pathway(GO:0038092)
0.0	0.1	GO:1990637	response to prolactin(GO:1990637)
0.0	0.0	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.3	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.3	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.2	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.0	0.2	GO:0002084	protein depalmitoylation(GO:0002084)
0.0	0.1	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0	0.3	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	1.4	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.3	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.3	GO:0010454	negative regulation of cell fate commitment(GO:0010454) lung goblet cell differentiation(GO:0060480)
0.0	0.3	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.3	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.1	GO:0097325	melanocyte proliferation(GO:0097325)
0.0	0.7	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.3	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.7	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0	0.2	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.3	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.1	GO:0039513	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0	0.8	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.1	GO:1903935	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0	0.3	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.2	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.4	GO:0048505	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.1	GO:0021886	hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0	0.2	GO:0042631	cellular response to water deprivation(GO:0042631)
0.0	1.1	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.4	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:1902473	regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.0	0.1	GO:0098907	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0	0.2	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.2	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.0	0.1	GO:0007173	epidermal growth factor receptor signaling pathway(GO:0007173)
0.0	1.0	GO:2000810	regulation of bicellular tight junction assembly(GO:2000810)
0.0	0.2	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	1.0	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.0	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
0.0	0.0	GO:0032347	regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.3	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.4	GO:0009650	UV protection(GO:0009650)
0.0	0.3	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.3	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.4	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:0061051	regulation of cell growth involved in cardiac muscle cell development(GO:0061050) positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0	0.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.0	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.4	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.3	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.3	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:1902723	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.5	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0	1.0	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.1	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0	0.4	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0	0.1	GO:1904398	positive regulation of neuromuscular junction development(GO:1904398)
0.0	0.6	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.1	GO:1903465	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0	0.3	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.2	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.2	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.1	GO:0002276	basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0	0.2	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.0	0.8	GO:0030182	neuron differentiation(GO:0030182)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.4	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.6	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.2	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.0	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.3	GO:1901862	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0	1.0	GO:0051646	mitochondrion localization(GO:0051646)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.6	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0	0.3	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0	0.4	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.4	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.8	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0	0.0	GO:0036369	transcription factor catabolic process(GO:0036369)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	1.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.5	GO:0006506	GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0	0.3	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.4	GO:0001946	lymphangiogenesis(GO:0001946)
0.0	0.1	GO:0042710	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0	0.1	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.0	0.1	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0	0.1	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0	0.1	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.3	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.2	GO:1904896	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0	0.6	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.1	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.0	0.1	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	1.3	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.2	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.5	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.3	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.2	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.5	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.1	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0032351	negative regulation of glucocorticoid metabolic process(GO:0031944) regulation of glucocorticoid biosynthetic process(GO:0031946) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0	0.1	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0	0.0	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.2	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.0	0.4	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.1	GO:0031063	regulation of histone deacetylation(GO:0031063)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.4	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.1	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.2	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	1.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.5	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983) response to sorbitol(GO:0072708)
0.0	0.1	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0046203	spermidine catabolic process(GO:0046203)
0.0	0.1	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0	0.1	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.4	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.3	GO:1902591	single-organism membrane budding(GO:1902591)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.5	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0009078	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.0	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.6	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
0.0	0.1	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.1	GO:0015793	glycerol transport(GO:0015793)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.2	GO:0048820	hair follicle maturation(GO:0048820)
0.0	0.1	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	0.2	GO:0036109	alpha-linolenic acid metabolic process(GO:0036109)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0045113	regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0	1.7	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	0.2	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	0.0	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.6	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.0	0.1	GO:0002933	lipid hydroxylation(GO:0002933)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.3	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0044253	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0	0.1	GO:0035811	negative regulation of urine volume(GO:0035811)
0.0	0.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.1	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.0	0.1	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0038155	interleukin-23-mediated signaling pathway(GO:0038155)
0.0	0.2	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.7	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	140.0	PID TGFBR PATHWAY	TGF-beta receptor signaling
1.3	35.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6	32.8	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.3	6.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.3	18.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.2	19.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	15.9	PID NOTCH PATHWAY	Notch signaling pathway
0.2	5.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	2.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	2.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	2.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	14.9	PID SHP2 PATHWAY	SHP2 signaling
0.2	12.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	7.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.2	7.8	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	6.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	4.9	PID FGF PATHWAY	FGF signaling pathway
0.1	7.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	4.3	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	3.7	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.6	PID CDC42 PATHWAY	CDC42 signaling events
0.1	1.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	8.4	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	1.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	2.4	PID BMP PATHWAY	BMP receptor signaling
0.0	9.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.9	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	1.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.2	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.9	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.9	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	8.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.6	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	1.2	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.2	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	2.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.3	0.5	PID S1P S1P4 PATHWAY	S1P4 pathway
0.2	2.7	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.2	7.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	8.0	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.2	15.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	14.9	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.2	0.8	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.2	3.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	2.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.2	0.7	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	1.0	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	5.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	9.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	1.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	12.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	2.9	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	0.6	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	2.7	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	0.7	PID EPO PATHWAY	EPO signaling pathway
0.1	2.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	4.0	PID IGF1 PATHWAY	IGF1 pathway
0.1	0.8	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	2.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	2.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	0.8	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	4.2	PID IFNG PATHWAY	IFN-gamma pathway
0.1	2.5	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	2.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	6.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	1.8	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	1.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	2.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	0.5	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	3.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	2.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	3.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	4.6	PID BCR 5PATHWAY	BCR signaling pathway
0.1	2.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	4.2	PID ATR PATHWAY	ATR signaling pathway
0.1	3.9	PID FOXO PATHWAY	FoxO family signaling
0.1	1.4	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	1.5	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	2.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	0.6	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	2.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	3.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	6.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	1.9	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	2.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	3.4	PID LKB1 PATHWAY	LKB1 signaling events
0.1	0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.1	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	1.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	0.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.1	PID ARF6 PATHWAY	Arf6 signaling events
0.1	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	0.8	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.1	0.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	1.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	0.7	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	1.2	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	0.8	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	1.7	PID FGF PATHWAY	FGF signaling pathway
0.1	0.6	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.1	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	1.9	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.9	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	3.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	2.7	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	2.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.6	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.8	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.5	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.5	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.6	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.3	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.5	PID ATM PATHWAY	ATM pathway
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.2	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.8	PID E2F PATHWAY	E2F transcription factor network
0.0	0.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.3	PID AP1 PATHWAY	AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	1.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.0	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.8	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	3.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.8	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	1.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	1.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.0	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.0	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	1.1	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	2.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	1.9	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.4	GO:0061386	closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1	0.2	GO:0071314	cellular response to cocaine(GO:0071314)
0.1	0.6	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1	0.2	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1	0.3	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.1	0.3	GO:0033078	extrathymic T cell differentiation(GO:0033078)
0.1	0.3	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.4	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.0	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.6	GO:0021702	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.1	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0	0.2	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	0.2	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.0	0.3	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0	0.5	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0	0.4	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.0	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.0	0.1	GO:0030035	microspike assembly(GO:0030035)
0.0	0.1	GO:0043335	protein unfolding(GO:0043335)
0.0	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:1901859	late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859) single-organism membrane invagination(GO:1902534)
0.0	0.3	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.4	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.2	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.0	GO:0002752	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.1	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.0	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
0.0	0.1	GO:0070341	fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.2	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	2.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	2.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.4	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.7	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.4	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.7	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
1.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.0	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	8.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	5.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	2.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	2.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.5	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	8.7	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.3	6.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	3.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	3.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	5.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	3.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	2.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	12.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	1.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	2.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.7	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	3.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	6.9	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.0	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.7	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	2.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	2.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.7	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	2.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	6.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	2.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.2	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.6	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	1.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.0	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	1.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	2.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	1.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	5.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	1.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	1.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.3	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	1.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	6.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.2	3.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	2.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.6	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	2.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	3.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	2.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	1.6	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	1.3	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.1	1.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.0	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	1.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	1.0	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.9	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1	4.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	1.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	1.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.0	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.4	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	1.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.5	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	2.2	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	4.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.5	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	2.2	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0	0.8	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	1.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.6	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	1.6	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.7	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
3.9	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.7	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	0.6	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.9	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	1.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.8	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	1.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
1.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.5	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	2.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	4.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	3.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	4.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	2.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	18.5	PID ALK1 PATHWAY	ALK1 signaling events
0.3	9.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	15.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.3	19.2	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.3	9.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	18.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	5.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	7.7	PID AURORA B PATHWAY	Aurora B signaling
0.1	19.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	13.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	3.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	4.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	5.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	2.0	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	1.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.9	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	2.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	1.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	1.1	NABA COLLAGENS	Genes encoding collagen proteins
0.0	1.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	1.5	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	1.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.1	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.6	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2	1.2	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1	0.6	GO:0046967	cytosol to ER transport(GO:0046967)
0.1	0.4	GO:0002384	hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1	0.5	GO:0042360	vitamin E metabolic process(GO:0042360)
0.1	0.4	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.1	1.0	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1	0.4	GO:0015808	L-alanine transport(GO:0015808)
0.1	0.3	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1	0.9	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	0.6	GO:0072718	response to cisplatin(GO:0072718)
0.1	0.3	GO:0061668	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.8	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	3.4	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.0	0.2	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	1.9	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	0.2	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.0	0.2	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.2	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0	0.2	GO:0061143	alveolar primary septum development(GO:0061143)
0.0	0.7	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:2001162	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0	0.5	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.2	GO:0033121	regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0	0.1	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.2	GO:0051458	corticotropin secretion(GO:0051458)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.3	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.7	GO:0045730	respiratory burst(GO:0045730)
0.0	0.5	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	0.2	GO:1902570	protein localization to nucleolus(GO:1902570)
0.0	0.5	GO:0006825	copper ion transport(GO:0006825)
0.0	0.3	GO:1901748	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0	0.2	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.2	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0032099	negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.0	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0	0.2	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0	0.3	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0015811	L-cystine transport(GO:0015811)
0.0	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.4	GO:0097503	sialylation(GO:0097503)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:1903322	positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:2001151	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0	0.1	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.7	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.0	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.0	0.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.5	GO:0019985	translesion synthesis(GO:0019985)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	7.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	6.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	2.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	5.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	3.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	6.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	4.6	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	1.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	2.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	2.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	4.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	0.8	REACTOME OPSINS	Genes involved in Opsins
0.1	0.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	0.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	2.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.9	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	3.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	6.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.0	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	4.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	1.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	3.1	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.5	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.8	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.6	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.5	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.4	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	2.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2	1.2	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	1.5	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.1	1.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	4.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.9	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.1	0.6	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	1.8	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.3	GO:0099542	retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1	0.2	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.2	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1	0.2	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0030185	nitric oxide transport(GO:0030185)
0.0	0.1	GO:2000543	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) positive regulation of gastrulation(GO:2000543)
0.0	1.0	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.3	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.7	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.2	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.2	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.0	0.2	GO:0035799	ureter maturation(GO:0035799)
0.0	0.5	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.0	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	1.1	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.3	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.1	GO:0007418	ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.0	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.0	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.3	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.3	7.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	2.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	5.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.1	1.8	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.7	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	3.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	0.8	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	2.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	6.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	1.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	1.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.8	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	1.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.8	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
1.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.9	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.0	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.2	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.7	GO:0005916	fascia adherens(GO:0005916)
0.4	1.3	GO:0005608	laminin-3 complex(GO:0005608)
0.3	1.7	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.3	2.1	GO:0005610	laminin-5 complex(GO:0005610)
0.2	1.6	GO:0016589	NURF complex(GO:0016589)
0.2	1.2	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	0.7	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1	1.8	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	1.8	GO:0031105	septin complex(GO:0031105)
0.1	1.6	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.9	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	1.7	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	1.0	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.6	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.3	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	3.0	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.5	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0014802	terminal cisterna(GO:0014802)
0.0	0.3	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	2.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.5	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	1.5	GO:0005604	basement membrane(GO:0005604)
0.0	1.8	GO:0030175	filopodium(GO:0030175)
0.0	4.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.4	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.4	GO:0000421	autophagosome membrane(GO:0000421)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	11.6	GO:0005916	fascia adherens(GO:0005916)
0.4	3.5	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.4	2.3	GO:0070435	Shc-EGFR complex(GO:0070435)
0.2	1.4	GO:0098845	postsynaptic endosome(GO:0098845)
0.2	2.6	GO:0005687	U4 snRNP(GO:0005687)
0.1	3.6	GO:0031143	pseudopodium(GO:0031143)
0.1	2.3	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.9	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.3	GO:0033269	internode region of axon(GO:0033269)
0.1	0.4	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	8.0	GO:0016459	myosin complex(GO:0016459)
0.1	0.4	GO:0097422	tubular endosome(GO:0097422)
0.1	0.7	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.8	GO:0030008	TRAPP complex(GO:0030008)
0.1	1.8	GO:0043218	compact myelin(GO:0043218)
0.1	0.4	GO:0070852	cell body fiber(GO:0070852)
0.1	1.2	GO:0000785	chromatin(GO:0000785)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	0.5	GO:1990909	Wnt signalosome(GO:1990909)
0.0	2.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.3	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.5	GO:0036038	MKS complex(GO:0036038)
0.0	0.7	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.5	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.3	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	3.7	GO:0043197	dendritic spine(GO:0043197)
0.0	0.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.9	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	2.5	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	4.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.9	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	1.0	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:1902560	GMP reductase complex(GO:1902560)
0.0	3.7	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	2.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.8	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	1.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:1990357	terminal web(GO:1990357)
0.1	0.5	GO:0043259	laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.1	4.6	GO:0045095	keratin filament(GO:0045095)
0.0	0.3	GO:0035976	AP1 complex(GO:0035976)
0.0	0.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.2	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	0.2	GO:0005927	muscle tendon junction(GO:0005927)
0.0	1.3	GO:0001533	cornified envelope(GO:0001533)
0.0	0.4	GO:0008290	F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	1.8	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.2	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.3	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.7	GO:0000786	nucleosome(GO:0000786)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.1	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	2.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.9	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	3.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.9	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	1.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	2.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	1.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	1.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	2.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	1.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.6	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	2.8	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.7	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.5	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.3	7.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	6.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	11.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	1.6	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	4.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	6.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	1.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	5.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	3.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	7.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	2.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	3.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	6.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	2.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	4.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	0.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	2.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	0.6	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	1.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	2.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	6.6	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.6	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.7	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	2.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	1.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.6	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	2.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.8	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	2.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.7	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.5	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.7	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	2.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.3	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	2.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.1	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.7	2.2	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.7	2.0	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.6	1.8	GO:1904481	response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.5	1.5	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.5	1.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.5	1.9	GO:0000255	allantoin metabolic process(GO:0000255)
0.5	1.4	GO:1904899	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4	1.2	GO:0072553	terminal button organization(GO:0072553)
0.4	1.6	GO:0097477	NMDA glutamate receptor clustering(GO:0097114) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.4	1.9	GO:1904636	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.4	0.8	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.4	1.8	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4	3.9	GO:0015886	heme transport(GO:0015886)
0.3	1.3	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.3	1.7	GO:0015862	uridine transport(GO:0015862)
0.3	1.0	GO:0019858	cytosine metabolic process(GO:0019858)
0.3	2.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.3	1.2	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.3	1.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3	0.8	GO:0032639	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.3	0.8	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3	0.8	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.3	0.8	GO:0070632	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.3	0.8	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.3	1.0	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.2	2.9	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.2	0.7	GO:0031133	regulation of axon diameter(GO:0031133)
0.2	1.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2	0.7	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.2	0.7	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2	0.9	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.2	1.1	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.2	0.8	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2	0.6	GO:1904772	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2	0.6	GO:0006014	D-ribose metabolic process(GO:0006014)
0.2	0.6	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.2	1.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	1.0	GO:0006740	NADPH regeneration(GO:0006740)
0.2	0.4	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.2	0.4	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.2	0.8	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.2	0.4	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.2	0.8	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2	0.6	GO:1903401	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transmembrane transport(GO:1903401) L-lysine import into cell(GO:1903410)
0.2	1.6	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.2	0.6	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.2	0.6	GO:0006059	hexitol metabolic process(GO:0006059)
0.2	0.6	GO:0006864	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2	0.7	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.2	0.9	GO:0009233	menaquinone metabolic process(GO:0009233)
0.2	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	0.8	GO:0019348	dolichol metabolic process(GO:0019348)
0.2	0.5	GO:1901535	regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.2	0.5	GO:0046098	guanine metabolic process(GO:0046098)
0.1	1.5	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.4	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	0.6	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.4	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.1	1.6	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	1.6	GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1	0.6	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	0.1	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1	0.6	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1	0.1	GO:0071426	ribonucleoprotein complex export from nucleus(GO:0071426)
0.1	1.4	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.4	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.1	1.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.1	0.4	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1	0.5	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.6	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.8	GO:0090032	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.1	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.4	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	0.5	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	1.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1	0.8	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.1	GO:0061110	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1	0.3	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
0.1	0.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	1.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	1.0	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.3	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.1	0.3	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1	0.4	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.5	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.3	GO:1901355	response to rapamycin(GO:1901355)
0.1	0.4	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.1	0.2	GO:0006288	base-excision repair, DNA ligation(GO:0006288)
0.1	0.4	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	1.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1	0.9	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.2	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1	0.7	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1	0.3	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	0.6	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.1	0.3	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.1	0.6	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	0.3	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.1	0.4	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.2	GO:0036090	cleavage furrow ingression(GO:0036090)
0.1	0.2	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1	0.2	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1	1.0	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.2	GO:0015743	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1	0.4	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.1	0.2	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1	0.2	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.5	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	0.3	GO:0071233	cellular response to leucine(GO:0071233)
0.1	0.1	GO:0044782	cilium organization(GO:0044782)
0.1	0.2	GO:0035054	septum secundum development(GO:0003285) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1	0.4	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.4	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.1	0.2	GO:2001171	positive regulation of ATP biosynthetic process(GO:2001171)
0.1	1.0	GO:0021892	cerebral cortex GABAergic interneuron differentiation(GO:0021892)
0.1	0.6	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.3	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.1	0.2	GO:0097056	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	1.3	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	0.7	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1	0.2	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1	0.3	GO:0007422	peripheral nervous system development(GO:0007422)
0.1	0.7	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.3	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.1	0.2	GO:1904479	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.1	0.3	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.4	GO:0051036	regulation of endosome size(GO:0051036)
0.1	0.4	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.3	GO:0048254	snoRNA localization(GO:0048254)
0.1	0.3	GO:1901079	positive regulation of relaxation of muscle(GO:1901079)
0.1	1.8	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.1	2.3	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.1	0.2	GO:0071301	transcription factor catabolic process(GO:0036369) cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1	0.4	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.1	0.9	GO:0006559	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.1	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1	0.2	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1	0.4	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.3	GO:0010731	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1	0.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1	1.0	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1	0.5	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.2	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1	1.7	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	2.2	GO:0006270	DNA replication initiation(GO:0006270)
0.1	0.5	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.1	0.6	GO:0007379	segment specification(GO:0007379)
0.1	0.6	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1	0.3	GO:0016240	autophagosome docking(GO:0016240)
0.1	0.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.1	0.4	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.1	0.9	GO:0045475	locomotor rhythm(GO:0045475)
0.1	0.4	GO:0035799	ureter maturation(GO:0035799)
0.1	0.4	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
0.1	1.8	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.2	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.1	0.7	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.5	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1	0.2	GO:0021997	neural plate axis specification(GO:0021997)
0.1	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	0.1	GO:0034759	regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0097359	UDP-glucosylation(GO:0097359)
0.0	0.2	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.0	1.1	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.9	GO:0050779	RNA destabilization(GO:0050779)
0.0	0.3	GO:1905024	regulation of potassium ion export(GO:1902302) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.0	0.2	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.1	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0	0.5	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.6	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.9	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.2	GO:1900125	regulation of hyaluronan biosynthetic process(GO:1900125)
0.0	0.4	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:1990523	negative regulation of neuromuscular junction development(GO:1904397) bone regeneration(GO:1990523)
0.0	0.3	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.8	GO:0038092	nodal signaling pathway(GO:0038092)
0.0	0.9	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.2	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.0	0.2	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.0	0.4	GO:0045008	depyrimidination(GO:0045008)
0.0	0.3	GO:0010468	regulation of gene expression(GO:0010468)
0.0	0.4	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.2	GO:0021784	postganglionic parasympathetic fiber development(GO:0021784)
0.0	0.3	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.3	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.0	0.6	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.2	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.3	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.0	0.1	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.0	0.8	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.0	1.5	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0043132	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.0	0.4	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.3	GO:0006868	glutamine transport(GO:0006868)
0.0	0.4	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.9	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.3	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0016246	RNA interference(GO:0016246)
0.0	0.4	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.4	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.3	GO:0009162	deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0	0.3	GO:0032264	IMP salvage(GO:0032264)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.4	GO:0006983	ER overload response(GO:0006983)
0.0	1.4	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.2	GO:0031929	TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.4	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.5	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.3	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0	0.5	GO:0051608	histamine transport(GO:0051608)
0.0	0.2	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.3	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.8	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.3	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.0	0.1	GO:0005985	sucrose metabolic process(GO:0005985)
0.0	0.2	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.0	0.5	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.9	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:0042262	DNA protection(GO:0042262)
0.0	0.5	GO:0014029	neural crest formation(GO:0014029)
0.0	0.5	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.1	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0	0.0	GO:0051885	positive regulation of anagen(GO:0051885)
0.0	0.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	1.7	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.3	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.2	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.1	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.2	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.1	GO:0042631	cellular response to water deprivation(GO:0042631)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.0	0.0	GO:1901679	nucleotide transmembrane transport(GO:1901679)
0.0	0.5	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0010212	response to ionizing radiation(GO:0010212)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.3	GO:0036376	sodium ion export from cell(GO:0036376)
0.0	0.5	GO:0016180	snRNA processing(GO:0016180)
0.0	0.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.3	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.1	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.0	0.1	GO:0051344	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.5	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.3	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.2	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.2	GO:0097106	postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.3	GO:0097502	mannosylation(GO:0097502)
0.0	0.0	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.2	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.2	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.4	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.0	GO:0070781	response to biotin(GO:0070781)
0.0	0.1	GO:1901993	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.4	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0038189	coronary vein morphogenesis(GO:0003169) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0	0.1	GO:0045212	negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0	0.7	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.1	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0	0.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.6	GO:0006400	tRNA modification(GO:0006400)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.2	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	1.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.2	GO:0097350	neutrophil clearance(GO:0097350)
0.0	0.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0009440	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0	0.1	GO:0010957	negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.2	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.0	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.2	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.2	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.0	0.2	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.5	GO:0008033	tRNA processing(GO:0008033)
0.0	0.1	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.1	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.1	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0	0.0	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)
0.0	0.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0	0.3	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.2	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.6	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.2	GO:0032310	prostaglandin secretion(GO:0032310)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0035811	negative regulation of urine volume(GO:0035811)
0.0	0.2	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.6	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0006281	DNA repair(GO:0006281)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0070933	histone H4 deacetylation(GO:0070933)
0.0	0.2	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.2	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	1.3	GO:0048477	oogenesis(GO:0048477)
0.0	0.1	GO:0051225	spindle assembly(GO:0051225)
0.0	0.1	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.0	0.5	GO:0051031	tRNA transport(GO:0051031)
0.0	0.2	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.2	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.2	GO:0070072	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.6	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.1	GO:0048511	rhythmic process(GO:0048511)
0.0	0.1	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.0	GO:0014002	astrocyte development(GO:0014002)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.4	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.2	GO:0097242	beta-amyloid clearance(GO:0097242)
0.0	0.0	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.3	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.2	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.3	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.4	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.6	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.3	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.4	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0072054	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	1.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.2	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.2	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.9	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.1	GO:0090344	negative regulation of cell aging(GO:0090344)
0.0	0.2	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0	0.9	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0071482	cellular response to light stimulus(GO:0071482)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.3	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0099565	ionotropic glutamate receptor signaling pathway(GO:0035235) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0	0.2	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.2	GO:0030220	platelet formation(GO:0030220)
0.0	0.0	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.1	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.0	0.0	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
0.0	0.6	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.0	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0042412	taurine biosynthetic process(GO:0042412)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.2	GO:0070585	protein localization to mitochondrion(GO:0070585)
0.0	0.4	GO:0010608	posttranscriptional regulation of gene expression(GO:0010608)
0.0	0.1	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	13.0	NABA COLLAGENS	Genes encoding collagen proteins
0.2	1.5	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.2	11.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.2	4.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	1.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.2	10.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.2	0.5	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.2	0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.2	2.9	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	8.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	0.6	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	6.9	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	11.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	1.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.9	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	7.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	0.6	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	0.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	3.6	PID AURORA A PATHWAY	Aurora A signaling
0.1	6.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	0.9	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	1.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	1.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	2.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	4.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	3.7	PID ATM PATHWAY	ATM pathway
0.1	2.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	0.9	PID BMP PATHWAY	BMP receptor signaling
0.1	0.7	PID FOXO PATHWAY	FoxO family signaling
0.1	2.0	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	3.0	PID AURORA B PATHWAY	Aurora B signaling
0.1	3.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	0.9	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	3.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	2.6	PID PLK1 PATHWAY	PLK1 signaling events
0.1	1.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	2.9	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	1.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.9	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	2.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.1	2.2	PID FGF PATHWAY	FGF signaling pathway
0.1	2.6	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	1.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	1.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	1.4	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	1.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.9	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.5	PID ALK2 PATHWAY	ALK2 signaling events
0.0	1.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	2.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	2.1	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.6	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	1.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.5	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.2	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.5	PID ATR PATHWAY	ATR signaling pathway
0.0	0.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.0	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.3	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.4	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	2.0	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	1.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	6.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	3.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.2	7.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	0.8	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	1.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.3	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	2.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	11.7	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
1.8	7.0	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.7	5.2	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
1.6	9.8	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
1.5	6.0	GO:0019086	late viral transcription(GO:0019086)
1.4	4.3	GO:0019858	cytosine metabolic process(GO:0019858)
1.3	3.8	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
1.2	2.3	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
1.2	3.5	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
1.1	3.4	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
1.1	3.4	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
1.1	10.9	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.1	5.3	GO:0019348	dolichol metabolic process(GO:0019348)
1.1	4.2	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
1.0	3.1	GO:0060018	astrocyte fate commitment(GO:0060018)
1.0	4.1	GO:2000314	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
1.0	3.0	GO:0036090	cleavage furrow ingression(GO:0036090)
1.0	7.7	GO:0010032	meiotic chromosome condensation(GO:0010032)
1.0	2.9	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.9	4.7	GO:0051182	coenzyme transport(GO:0051182)
0.9	2.8	GO:2000173	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.9	12.0	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.9	2.6	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.9	3.4	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.8	5.9	GO:0070269	pyroptosis(GO:0070269)
0.8	4.1	GO:0010520	meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.8	2.4	GO:0070541	response to platinum ion(GO:0070541)
0.8	2.4	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.8	8.8	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.8	0.8	GO:1903490	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.8	2.3	GO:0007538	primary sex determination(GO:0007538)
0.8	3.0	GO:0043144	snoRNA processing(GO:0043144)
0.7	2.2	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.7	6.6	GO:0016584	nucleosome positioning(GO:0016584)
0.7	2.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.7	4.3	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.7	2.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.7	2.1	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.7	2.0	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.7	6.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.7	2.0	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.7	3.3	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.7	4.6	GO:1902915	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.7	2.0	GO:1903970	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.7	1.3	GO:0046601	positive regulation of centriole replication(GO:0046601)
0.6	3.9	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.6	7.0	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.6	1.9	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.6	1.9	GO:0060151	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.6	3.6	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.6	4.8	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.6	1.2	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.6	4.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.6	1.8	GO:1902530	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.6	1.7	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.6	2.9	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.6	5.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.6	7.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.6	1.7	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.5	2.7	GO:0042256	mature ribosome assembly(GO:0042256)
0.5	5.4	GO:0010265	SCF complex assembly(GO:0010265)
0.5	2.7	GO:1902904	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.5	39.9	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.5	0.5	GO:0031929	TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
0.5	2.1	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.5	7.4	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.5	2.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.5	6.3	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.5	3.6	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.5	4.7	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.5	3.6	GO:0035624	receptor transactivation(GO:0035624)
0.5	2.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.5	2.1	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.5	1.5	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.5	1.5	GO:0051685	maintenance of ER location(GO:0051685)
0.5	1.5	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.5	1.5	GO:0048250	mitochondrial iron ion transport(GO:0048250)
0.5	1.0	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.5	1.5	GO:0051697	protein delipidation(GO:0051697)
0.5	1.5	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.5	0.5	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.5	2.9	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.5	3.4	GO:1902267	polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.5	2.9	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.5	1.4	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.5	1.4	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.5	0.5	GO:0071046	nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.5	3.2	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.5	1.4	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.5	5.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.5	1.4	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.4	0.9	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.4	2.2	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.4	1.3	GO:0046098	guanine metabolic process(GO:0046098)
0.4	1.3	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.4	1.8	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.4	1.3	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.4	0.4	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.4	4.7	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.4	11.1	GO:0034453	microtubule anchoring(GO:0034453)
0.4	3.3	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.4	2.1	GO:0009233	menaquinone metabolic process(GO:0009233)
0.4	1.2	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.4	1.2	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.4	1.6	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.4	2.0	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.4	1.2	GO:0051095	regulation of helicase activity(GO:0051095)
0.4	2.0	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4	3.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.4	3.6	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.4	1.6	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.4	1.6	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.4	0.8	GO:0015960	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.4	2.8	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.4	1.6	GO:0048496	maintenance of organ identity(GO:0048496)
0.4	17.7	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4	2.7	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
0.4	1.9	GO:0033274	response to vitamin B2(GO:0033274) chromatin maintenance(GO:0070827) heterochromatin maintenance(GO:0070829)
0.4	4.6	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.4	15.1	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.4	1.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.4	1.1	GO:1902499	positive regulation of protein autoubiquitination(GO:1902499)
0.4	4.8	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.4	0.4	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.4	1.8	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.4	2.5	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.4	1.8	GO:0040031	snRNA modification(GO:0040031)
0.4	1.1	GO:0000967	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.4	3.6	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4	1.8	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.4	4.3	GO:0015074	DNA integration(GO:0015074)
0.4	1.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689) positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4	1.4	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4	1.8	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.4	2.1	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.3	15.0	GO:0043486	histone exchange(GO:0043486)
0.3	2.4	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405)
0.3	2.4	GO:0006102	isocitrate metabolic process(GO:0006102)
0.3	3.1	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.3	3.1	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3	1.0	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.3	4.1	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3	1.4	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.3	0.7	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.3	1.0	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3	1.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.3	1.6	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.3	2.6	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3	1.9	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.3	0.9	GO:0050720	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) regulation of progesterone biosynthetic process(GO:2000182)
0.3	0.6	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.3	2.2	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.3	2.4	GO:0060017	parathyroid gland development(GO:0060017)
0.3	1.5	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3	1.5	GO:0016240	autophagosome docking(GO:0016240)
0.3	6.9	GO:0034389	lipid particle organization(GO:0034389)
0.3	1.7	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.3	0.9	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.3	5.4	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.3	3.1	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.3	1.4	GO:0006733	oxidoreduction coenzyme metabolic process(GO:0006733)
0.3	1.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	13.4	GO:0019985	translesion synthesis(GO:0019985)
0.3	1.4	GO:0034971	regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R17 methylation(GO:0034971)
0.3	1.1	GO:0071233	cellular response to leucine(GO:0071233)
0.3	0.8	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.3	18.5	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3	0.8	GO:0015680	intracellular copper ion transport(GO:0015680)
0.3	2.4	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.3	2.6	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3	0.8	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3	2.0	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.3	0.8	GO:0003383	apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
0.3	0.8	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.3	1.3	GO:0042182	ketone catabolic process(GO:0042182)
0.2	1.0	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.2	0.2	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.2	0.5	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.2	1.4	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.2	1.9	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.2	2.8	GO:0046051	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2	2.6	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2	1.4	GO:0051036	regulation of endosome size(GO:0051036)
0.2	5.1	GO:0030488	tRNA methylation(GO:0030488)
0.2	2.5	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.2	3.4	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.2	0.7	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2	1.1	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.2	2.4	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2	0.4	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.2	2.0	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.2	0.4	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.2	0.7	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.2	5.2	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2	1.3	GO:0008298	intracellular mRNA localization(GO:0008298)
0.2	0.6	GO:2001045	closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2	1.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.2	3.6	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.2	1.9	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.2	0.4	GO:0009083	branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.2	2.7	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2	0.8	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.2	2.6	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.2	3.2	GO:0043248	proteasome assembly(GO:0043248)
0.2	1.6	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.2	1.4	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2	1.7	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.2	1.7	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2	0.8	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.2	0.7	GO:0009838	abscission(GO:0009838)
0.2	1.7	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2	4.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.2	4.1	GO:1903392	negative regulation of adherens junction organization(GO:1903392)
0.2	1.7	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2	1.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.2	5.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2	1.3	GO:0044036	cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.2	1.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.2	2.0	GO:0009303	rRNA transcription(GO:0009303)
0.2	0.9	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.2	1.7	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.2	2.1	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	1.4	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.2	2.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.2	1.5	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.2	2.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2	1.5	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2	1.0	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2	2.2	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.2	1.2	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2	2.3	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.2	0.3	GO:0030242	pexophagy(GO:0030242)
0.2	0.2	GO:0034398	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2	1.8	GO:0045475	locomotor rhythm(GO:0045475)
0.2	2.0	GO:0051451	myoblast migration(GO:0051451)
0.2	1.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.2	1.1	GO:0051415	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2	1.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.2	1.6	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.2	1.6	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.2	3.2	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.2	0.8	GO:0070475	rRNA base methylation(GO:0070475)
0.2	0.6	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.2	1.8	GO:0016578	histone deubiquitination(GO:0016578)
0.2	0.5	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
0.2	0.8	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.2	0.8	GO:0072553	terminal button organization(GO:0072553)
0.2	1.4	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.2	1.7	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.1	8.1	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.1	2.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	0.6	GO:0046189	melanin metabolic process(GO:0006582) phenol-containing compound metabolic process(GO:0018958) secondary metabolic process(GO:0019748) melanin biosynthetic process(GO:0042438) secondary metabolite biosynthetic process(GO:0044550) phenol-containing compound biosynthetic process(GO:0046189)
0.1	6.4	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	0.3	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	2.5	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.1	7.6	GO:0042255	ribosome assembly(GO:0042255)
0.1	1.9	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	0.7	GO:0001315	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1	0.6	GO:0006875	cellular metal ion homeostasis(GO:0006875)
0.1	1.5	GO:0015886	heme transport(GO:0015886)
0.1	0.4	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.1	0.3	GO:0046502	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.7	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.1	7.3	GO:0070897	DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1	2.0	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1	3.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	0.5	GO:0043335	protein unfolding(GO:0043335)
0.1	12.1	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.1	1.3	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	0.7	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1	0.5	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1	0.3	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.1	3.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	3.3	GO:0006400	tRNA modification(GO:0006400)
0.1	0.4	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.1	1.6	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	0.7	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	1.3	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.1	1.4	GO:0006105	succinate metabolic process(GO:0006105)
0.1	0.4	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1	0.4	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.1	0.3	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1	0.6	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	0.9	GO:0044728	DNA methylation or demethylation(GO:0044728)
0.1	0.8	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	1.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	8.5	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	2.1	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	1.6	GO:0006450	regulation of translational fidelity(GO:0006450)
0.1	2.5	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1	9.1	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1	1.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.6	GO:0051661	maintenance of centrosome location(GO:0051661)
0.1	2.8	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	1.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.4	GO:0007062	sister chromatid cohesion(GO:0007062)
0.1	0.8	GO:0060013	righting reflex(GO:0060013)
0.1	0.3	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.8	GO:0006323	DNA packaging(GO:0006323)
0.1	0.2	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	1.8	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.8	GO:0002759	regulation of antimicrobial humoral response(GO:0002759)
0.1	0.9	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1	0.3	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.5	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.1	0.7	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	1.4	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.1	0.5	GO:0032099	negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1	1.1	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.1	1.4	GO:0007097	nuclear migration(GO:0007097)
0.1	1.2	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1	1.1	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.1	0.3	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.1	0.2	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1	2.6	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.1	0.6	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	0.4	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	2.4	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.1	2.3	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.1	4.8	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	1.0	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.1	1.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.3	GO:0051057	positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1	2.1	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.1	1.7	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.1	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1	5.6	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.1	1.1	GO:0021924	cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1	0.6	GO:0045007	depurination(GO:0045007)
0.1	0.4	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	1.4	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	0.8	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1	1.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.6	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	0.6	GO:0046958	nonassociative learning(GO:0046958)
0.1	1.0	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1	0.4	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	3.3	GO:0006270	DNA replication initiation(GO:0006270)
0.1	0.2	GO:0048318	axial mesoderm development(GO:0048318)
0.1	2.4	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.1	0.8	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.1	0.4	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1	1.4	GO:0006012	galactose metabolic process(GO:0006012)
0.1	2.3	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.1	0.6	GO:0006265	DNA topological change(GO:0006265)
0.1	1.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.2	GO:0032048	cardiolipin metabolic process(GO:0032048)
0.1	0.4	GO:0070166	enamel mineralization(GO:0070166)
0.1	8.6	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
0.1	1.2	GO:0030220	platelet formation(GO:0030220)
0.1	1.2	GO:0098781	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) ncRNA transcription(GO:0098781)
0.1	0.2	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	0.3	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.1	1.6	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.1	5.1	GO:0031016	pancreas development(GO:0031016)
0.1	5.4	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.1	1.2	GO:0006413	translational initiation(GO:0006413)
0.1	0.8	GO:0044803	multi-organism membrane organization(GO:0044803)
0.1	3.4	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.4	GO:0071321	cellular response to cGMP(GO:0071321)
0.1	0.1	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.1	0.5	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	3.4	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.1	4.7	GO:0006354	DNA-templated transcription, elongation(GO:0006354)
0.1	0.7	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1	0.7	GO:0060148	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1	0.8	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1	0.3	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	2.2	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
0.1	0.8	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.7	GO:0001702	gastrulation with mouth forming second(GO:0001702)
0.1	1.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	1.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	0.2	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1	0.4	GO:1905146	lysosomal protein catabolic process(GO:1905146)
0.1	1.7	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	1.5	GO:0046039	GTP metabolic process(GO:0046039)
0.1	2.5	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.6	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.1	1.6	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.1	0.3	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1	0.8	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.1	0.2	GO:0071774	response to fibroblast growth factor(GO:0071774)
0.1	0.6	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1	1.8	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1	0.4	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.1	1.5	GO:0014002	astrocyte development(GO:0014002)
0.1	1.9	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1	1.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.5	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0	0.5	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.3	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.9	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	2.3	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.6	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.4	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.8	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.3	GO:0098780	response to mitochondrial depolarisation(GO:0098780)
0.0	0.8	GO:2000463	positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0	0.4	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	1.0	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.7	GO:0001502	cartilage condensation(GO:0001502)
0.0	3.2	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	2.7	GO:0006968	cellular defense response(GO:0006968)
0.0	0.3	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	1.4	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
0.0	3.0	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0	2.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.6	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.5	GO:0002643	regulation of tolerance induction(GO:0002643)
0.0	0.1	GO:0006414	translational elongation(GO:0006414)
0.0	9.8	GO:0006397	mRNA processing(GO:0006397)
0.0	0.8	GO:0070328	acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0	0.1	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0	0.5	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.9	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.6	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.9	GO:0044764	multi-organism cellular process(GO:0044764)
0.0	0.2	GO:0043491	protein kinase B signaling(GO:0043491)
0.0	0.1	GO:0018201	N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.0	3.5	GO:0007050	cell cycle arrest(GO:0007050)
0.0	0.8	GO:0008033	tRNA processing(GO:0008033)
0.0	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.1	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.7	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.2	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0	0.2	GO:0022900	electron transport chain(GO:0022900)
0.0	0.6	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.4	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.6	GO:0070228	regulation of lymphocyte apoptotic process(GO:0070228)
0.0	0.6	GO:0090659	walking behavior(GO:0090659)
0.0	6.9	GO:0009116	nucleoside metabolic process(GO:0009116)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.4	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	1.1	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.3	GO:0001881	receptor recycling(GO:0001881)
0.0	2.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.0	0.2	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	2.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.4	GO:0032094	response to food(GO:0032094)
0.0	1.6	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.5	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0	0.4	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.2	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	2.1	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	1.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	1.7	GO:0031398	positive regulation of protein ubiquitination(GO:0031398)
0.0	0.2	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.2	GO:0060828	regulation of canonical Wnt signaling pathway(GO:0060828)
0.0	0.1	GO:0035418	protein localization to synapse(GO:0035418)
0.0	0.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.8	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.0	0.0	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.0	0.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.1	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.0	0.6	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0	0.1	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.6	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.3	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:0098856	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.2	GO:0017038	protein import(GO:0017038)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.2	GO:0010842	retina layer formation(GO:0010842)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.7	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	7.1	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.6	5.5	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3	1.0	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.3	1.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.3	4.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.3	0.9	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3	1.7	GO:0045569	TRAIL binding(GO:0045569)
0.3	3.3	GO:0045159	myosin II binding(GO:0045159)
0.3	2.7	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3	4.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	3.4	GO:0050700	CARD domain binding(GO:0050700)
0.2	3.4	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.2	1.1	GO:0002046	opsin binding(GO:0002046)
0.2	0.8	GO:0004743	pyruvate kinase activity(GO:0004743)
0.2	5.0	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	1.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.7	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1	3.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	1.5	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.1	2.7	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	0.4	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1	0.3	GO:0008097	5S rRNA binding(GO:0008097)
0.1	0.4	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.6	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.9	GO:0051425	PTB domain binding(GO:0051425)
0.1	0.4	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	4.1	GO:0042056	chemoattractant activity(GO:0042056)
0.1	1.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.6	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1	5.0	GO:0042379	chemokine receptor binding(GO:0042379)
0.1	8.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.9	GO:0001972	retinoic acid binding(GO:0001972)
0.1	0.5	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1	0.4	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	1.4	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	11.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.3	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	0.7	GO:0051434	BH3 domain binding(GO:0051434)
0.1	10.7	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	4.7	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1	0.2	GO:0004962	endothelin receptor activity(GO:0004962)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.9	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.7	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.3	GO:0070728	leucine binding(GO:0070728)
0.0	1.3	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.2	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.5	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.2	GO:0016499	orexin receptor activity(GO:0016499)
0.0	0.6	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	1.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.5	GO:0031432	titin binding(GO:0031432)
0.0	3.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	0.6	GO:0000339	RNA cap binding(GO:0000339)
0.0	7.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.2	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.2	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.4	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.4	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.3	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.8	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.4	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	5.1	GO:0003924	GTPase activity(GO:0003924)
0.0	0.4	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	2.7	GO:0051015	actin filament binding(GO:0051015)
0.0	0.0	GO:0032217	riboflavin transporter activity(GO:0032217)
0.0	1.1	GO:0004519	endonuclease activity(GO:0004519)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	2.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	2.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	5.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	2.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	1.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.9	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	3.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	2.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.0	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.7	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.7	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.1	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.3	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.7	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	1.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.0	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.3	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.3	3.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.3	3.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3	4.9	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.7	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2	3.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.4	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.1	2.2	GO:0030478	actin cap(GO:0030478)
0.1	2.4	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	0.6	GO:0033655	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1	1.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.4	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1	1.4	GO:0031209	SCAR complex(GO:0031209)
0.1	0.9	GO:0071953	elastic fiber(GO:0071953)
0.1	0.6	GO:0036021	endolysosome lumen(GO:0036021)
0.1	6.1	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	1.5	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.4	GO:0032807	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1	6.8	GO:0005882	intermediate filament(GO:0005882)
0.1	2.0	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.7	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.9	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	1.7	GO:0000421	autophagosome membrane(GO:0000421)
0.0	1.1	GO:0031082	BLOC complex(GO:0031082)
0.0	3.1	GO:0005776	autophagosome(GO:0005776)
0.0	0.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	8.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.7	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.3	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.8	GO:0030057	desmosome(GO:0030057)
0.0	0.7	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	0.8	GO:0036379	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0	0.4	GO:0090543	Flemming body(GO:0090543)
0.0	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.9	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.4	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.5	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	5.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	1.6	GO:0043202	lysosomal lumen(GO:0043202)
0.0	1.6	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.1	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0	0.4	GO:0051233	spindle midzone(GO:0051233)
0.0	0.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.3	GO:0032420	stereocilium(GO:0032420)
0.0	0.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.8	GO:0005604	basement membrane(GO:0005604)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.7	2.1	GO:1900073	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.4	1.5	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.4	1.1	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.3	1.4	GO:0002503	peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.3	2.6	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3	0.9	GO:0002522	leukocyte migration involved in immune response(GO:0002522)
0.3	3.3	GO:0034465	response to carbon monoxide(GO:0034465)
0.3	3.4	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3	0.5	GO:0007412	axon target recognition(GO:0007412)
0.3	2.0	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.2	1.9	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2	0.7	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2	1.3	GO:0090131	mesenchyme migration(GO:0090131)
0.2	0.8	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.2	0.6	GO:0090291	negative regulation of osteoclast proliferation(GO:0090291)
0.2	0.6	GO:1904933	cardiac right atrium morphogenesis(GO:0003213) positive regulation of anagen(GO:0051885) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) regulation of cell proliferation in midbrain(GO:1904933)
0.2	1.4	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.2	1.0	GO:0001810	regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.2	0.8	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2	0.6	GO:0045062	extrathymic T cell selection(GO:0045062)
0.2	0.6	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.2	0.6	GO:0072276	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2	1.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2	0.4	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2	0.5	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.2	0.5	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.2	0.2	GO:0060300	regulation of cytokine activity(GO:0060300)
0.2	0.3	GO:0065002	intracellular protein transmembrane transport(GO:0065002)
0.2	3.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.2	0.7	GO:0072183	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.2	11.7	GO:0006910	phagocytosis, recognition(GO:0006910)
0.2	0.5	GO:1904395	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.2	0.5	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.2	0.7	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.2	0.3	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.2	0.6	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.2	0.8	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.2	1.1	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2	0.5	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2	0.5	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.2	0.6	GO:1904457	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.2	1.6	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2	0.5	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.2	1.5	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.7	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.6	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.1	0.4	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.1	0.4	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1	0.9	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.1	0.6	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.1	1.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.8	GO:0046785	microtubule polymerization(GO:0046785)
0.1	0.7	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1	0.6	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.1	0.4	GO:0051311	meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1	0.4	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.1	0.3	GO:0034340	response to type I interferon(GO:0034340)
0.1	0.5	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
0.1	0.4	GO:1905064	negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1	0.5	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.4	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1	0.4	GO:0071529	cementum mineralization(GO:0071529)
0.1	0.9	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.4	GO:0021569	rhombomere 3 development(GO:0021569)
0.1	0.3	GO:0070256	negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1	0.6	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.4	GO:2000729	myotome development(GO:0061055) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	1.5	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.2	GO:0023021	termination of signal transduction(GO:0023021)
0.1	0.4	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1	0.4	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.1	0.9	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.4	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1	0.4	GO:0060974	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.1	0.9	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.5	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.1	0.5	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1	0.6	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.4	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.5	GO:0071306	cellular response to vitamin E(GO:0071306)
0.1	1.4	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.6	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.1	0.2	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.1	0.1	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.1	0.2	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	1.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	1.7	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.1	0.2	GO:0072019	proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.1	0.4	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	0.3	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.1	0.1	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.3	GO:0060127	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1	0.2	GO:0034759	regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.1	1.2	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.3	GO:0072709	cellular response to sorbitol(GO:0072709)
0.1	0.4	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1	0.2	GO:1902019	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1	1.4	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.3	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	0.2	GO:1903413	cellular response to bile acid(GO:1903413)
0.1	0.3	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1	0.5	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.3	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.4	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.3	GO:0042223	response to molecule of fungal origin(GO:0002238) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.1	0.3	GO:0061056	sclerotome development(GO:0061056)
0.1	0.5	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	0.3	GO:0036060	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1	0.6	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.1	0.2	GO:0097325	melanocyte proliferation(GO:0097325)
0.1	0.3	GO:0019858	cytosine metabolic process(GO:0019858)
0.1	0.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.1	0.3	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1	0.4	GO:1904075	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1	0.1	GO:0021537	telencephalon development(GO:0021537)
0.1	0.3	GO:0071810	regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1	0.6	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1	0.3	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	0.1	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.1	0.2	GO:0045402	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1	0.2	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.7	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1	0.4	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.1	0.5	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.1	0.2	GO:0042940	D-amino acid transport(GO:0042940)
0.1	0.4	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.1	0.5	GO:0070458	cellular detoxification of nitrogen compound(GO:0070458)
0.1	0.3	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.3	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	0.2	GO:0071789	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1	0.4	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.2	GO:0021558	trochlear nerve development(GO:0021558)
0.1	0.2	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1	0.8	GO:0060022	hard palate development(GO:0060022)
0.1	4.6	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	0.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	4.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.1	GO:1903378	positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1	0.2	GO:1903487	regulation of lactation(GO:1903487)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	1.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.3	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1	0.2	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.1	0.4	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.1	0.2	GO:0051685	maintenance of ER location(GO:0051685)
0.1	0.3	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.1	0.6	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1	0.1	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	0.3	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	0.5	GO:0001554	luteolysis(GO:0001554)
0.1	0.2	GO:0032679	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1	2.2	GO:0045730	respiratory burst(GO:0045730)
0.1	0.3	GO:0071461	cellular response to redox state(GO:0071461)
0.1	0.2	GO:0010571	positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1	0.3	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.1	GO:1900063	regulation of peroxisome organization(GO:1900063)
0.1	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.7	GO:0051601	exocyst localization(GO:0051601)
0.1	0.5	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	0.5	GO:1900044	negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	1.1	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.1	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1	0.5	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.1	0.5	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1	0.5	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	0.1	GO:0032620	interleukin-17 production(GO:0032620)
0.1	0.2	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.1	0.2	GO:1903722	regulation of centriole elongation(GO:1903722)
0.1	0.6	GO:0033227	dsRNA transport(GO:0033227)
0.1	0.4	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.1	0.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.3	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1	0.2	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1	0.6	GO:0032264	IMP salvage(GO:0032264)
0.1	0.3	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	0.5	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	0.5	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.1	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
0.1	0.1	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.1	GO:1902739	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1	1.0	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1	1.1	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	0.2	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1	0.2	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1	0.2	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.1	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	0.1	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.1	0.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.2	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.1	2.0	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.1	0.1	GO:0006529	asparagine biosynthetic process(GO:0006529)
0.1	0.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	0.3	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.7	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.1	0.2	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1	0.2	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1	5.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.1	0.2	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.8	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.5	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.1	0.8	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.3	GO:0070842	aggresome assembly(GO:0070842)
0.1	0.1	GO:0035087	targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1	0.3	GO:0061143	alveolar primary septum development(GO:0061143)
0.1	0.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1	2.2	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	0.2	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	0.2	GO:0036371	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1	0.9	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.2	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.1	0.4	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	1.8	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	0.3	GO:1903588	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	0.2	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1	7.9	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0	0.2	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.2	GO:2000567	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0	0.2	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.4	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.4	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.3	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.5	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.7	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.0	GO:1903061	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0	0.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.0	0.1	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.1	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.1	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0	0.2	GO:0090299	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0	0.1	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0	0.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.1	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.0	0.0	GO:0071231	cellular response to folic acid(GO:0071231)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.3	GO:0014831	gastro-intestinal system smooth muscle contraction(GO:0014831)
0.0	0.4	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.6	GO:0051882	mitochondrial depolarization(GO:0051882)
0.0	0.2	GO:0050848	regulation of calcium-mediated signaling(GO:0050848)
0.0	0.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.1	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0050757	thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0	0.4	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.0	0.1	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.4	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.1	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.7	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	0.2	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.2	GO:0035627	ceramide transport(GO:0035627)
0.0	0.2	GO:0061358	adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) negative regulation of Wnt protein secretion(GO:0061358)
0.0	0.4	GO:0014870	response to muscle inactivity(GO:0014870)
0.0	0.1	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.0	1.5	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0038179	neurotrophin signaling pathway(GO:0038179)
0.0	0.1	GO:1905232	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) cellular response to L-glutamate(GO:1905232) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.1	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.0	0.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.1	GO:0023016	signal transduction by trans-phosphorylation(GO:0023016)
0.0	0.2	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:0051643	endoplasmic reticulum localization(GO:0051643)
0.0	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.2	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.2	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.0	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.0	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.3	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	1.3	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.0	1.7	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0	0.2	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.0	0.2	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.1	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.0	0.1	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0	0.2	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.1	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.0	0.7	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.3	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.2	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.0	0.1	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.0	0.1	GO:1900369	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.0	0.1	GO:0070086	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0	0.1	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.0	GO:0071315	cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.0	0.2	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.5	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.8	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.0	0.1	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.5	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.2	GO:0015793	glycerol transport(GO:0015793)
0.0	0.1	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:2000078	glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0	0.3	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.1	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.2	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.6	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.2	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.2	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.9	GO:0042749	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.1	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0	0.1	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0	0.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.2	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.3	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.1	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.2	GO:0098704	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0	0.1	GO:0036116	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0	0.1	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0	0.1	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.1	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0	0.1	GO:0003064	regulation of heart rate by hormone(GO:0003064)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.2	GO:0070383	DNA cytosine deamination(GO:0070383)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.2	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.2	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283)
0.0	0.2	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.0	GO:0019081	viral translation(GO:0019081) IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.2	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	0.0	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.0	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0	0.1	GO:2000669	negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0	0.1	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.0	0.1	GO:0070092	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0032849	regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849)
0.0	0.2	GO:0006941	striated muscle contraction(GO:0006941)
0.0	0.3	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.0	0.0	GO:0072434	signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0	0.0	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.0	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:2000611	thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.2	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.0	0.6	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.1	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.0	0.1	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0	0.1	GO:0003360	brainstem development(GO:0003360)
0.0	0.1	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.0	0.2	GO:0019418	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0	0.1	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:0032094	response to food(GO:0032094)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.1	GO:0072136	kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136)
0.0	0.1	GO:0035655	interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0	0.0	GO:0015966	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.1	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:0061217	regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0	0.3	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0046066	dGDP metabolic process(GO:0046066)
0.0	0.2	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.2	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.0	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0	0.4	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.3	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.1	GO:0038170	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0	0.1	GO:0009441	glycolate metabolic process(GO:0009441)
0.0	0.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.1	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.6	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.0	0.0	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.0	0.0	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0	0.4	GO:0006183	GTP biosynthetic process(GO:0006183)
0.0	0.2	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:1903209	positive regulation of oxidative stress-induced cell death(GO:1903209)
0.0	0.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.1	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0016240	autophagosome docking(GO:0016240)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.0	0.1	GO:0002278	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0	0.2	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.2	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.4	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.0	GO:0042346	positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0	0.0	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.1	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.2	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.0	0.1	GO:0006116	fructose catabolic process(GO:0006001) NADH oxidation(GO:0006116) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.2	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.1	GO:1904550	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0	0.1	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0035617	stress granule disassembly(GO:0035617)
0.0	0.1	GO:0097696	JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0	0.5	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0045136	thelarche(GO:0042695) development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.3	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.1	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.2	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.0	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.2	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.3	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.0	0.2	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.0	0.0	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.2	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0099551	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0	0.1	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.3	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.0	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.4	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.1	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.3	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.1	GO:0070977	bone maturation(GO:0070977)
0.0	0.1	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.1	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106) lipoate biosynthetic process(GO:0009107)
0.0	0.1	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0	0.4	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.1	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0	0.4	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.2	GO:0023019	signal transduction involved in regulation of gene expression(GO:0023019)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.4	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0072366	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0030185	nitric oxide transport(GO:0030185)
0.0	0.1	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.0	GO:0072584	caveolin-mediated endocytosis(GO:0072584)
0.0	0.3	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	0.2	GO:0060536	cartilage morphogenesis(GO:0060536)
0.0	0.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.0	0.1	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.2	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	2.2	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0	0.0	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.0	0.0	GO:1904869	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0	0.0	GO:0009081	valine metabolic process(GO:0006573) branched-chain amino acid metabolic process(GO:0009081)
0.0	0.1	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.0	GO:0034971	histone H3-R17 methylation(GO:0034971)
0.0	0.4	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.1	GO:0090520	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.3	GO:0072539	T-helper 17 cell differentiation(GO:0072539)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0019083	viral transcription(GO:0019083)
0.0	0.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.0	0.2	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.6	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0	0.3	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.3	GO:0003016	respiratory system process(GO:0003016)
0.0	0.0	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0	0.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	3.5	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.3	GO:0006298	mismatch repair(GO:0006298)
0.0	0.0	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.1	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0	0.1	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.1	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.0	0.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.0	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0071346	cellular response to interferon-gamma(GO:0071346)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0042262	DNA protection(GO:0042262)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0015680	intracellular copper ion transport(GO:0015680)
0.0	0.1	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.1	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0035377	transepithelial water transport(GO:0035377)
0.0	0.0	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0090650	response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0	0.3	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.0	0.0	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.0	0.0	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.0	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.0	GO:1903818	positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.1	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.1	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0014854	response to inactivity(GO:0014854)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0033151	V(D)J recombination(GO:0033151)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.0	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.2	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.1	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.0	GO:1903401	L-lysine transmembrane transport(GO:1903401)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.1	GO:1904995	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.0	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0	0.1	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.4	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.0	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.0	0.1	GO:0014848	urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:1904396	regulation of neuromuscular junction development(GO:1904396)
0.0	0.1	GO:1902669	positive regulation of axon guidance(GO:1902669)
0.0	0.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.3	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:2001206	positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.5	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	1.2	GO:0007286	spermatid development(GO:0007286)
0.0	0.1	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.5	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0033198	response to ATP(GO:0033198)
0.0	0.1	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.1	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.3	GO:0048536	spleen development(GO:0048536)
0.0	0.1	GO:0060965	negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.4	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.0	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.0	0.3	GO:0008214	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.2	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.2	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.2	GO:0046039	GTP metabolic process(GO:0046039)
0.0	0.0	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.4	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.0	0.4	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.0	GO:1903348	positive regulation of bicellular tight junction assembly(GO:1903348)
0.0	0.0	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:0021544	subpallium development(GO:0021544) striatum development(GO:0021756)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.0	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.0	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.0	0.0	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.0	0.0	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0007059	chromosome segregation(GO:0007059)
0.0	0.1	GO:0030324	lung development(GO:0030324)
0.0	0.0	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.0	GO:2000824	negative regulation of androgen receptor activity(GO:2000824)
0.0	0.0	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.2	GO:0042391	regulation of membrane potential(GO:0042391)
0.0	0.0	GO:0021984	adenohypophysis development(GO:0021984)
0.0	0.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.1	GO:1990592	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.0	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.0	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.0	GO:0034036	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0	0.1	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.0	GO:0015824	proline transport(GO:0015824)
0.0	0.0	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.0	0.1	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.0	1.4	GO:0045047	protein targeting to ER(GO:0045047)
0.0	0.1	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.9	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
2.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5	REACTOME POL SWITCHING	Genes involved in Polymerase switching
1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
1.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
1.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.6	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.6	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.7	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.5	REACTOME KINESINS	Genes involved in Kinesins
0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
1.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.5	60.4	GO:1990111	spermatoproteasome complex(GO:1990111)
2.9	20.2	GO:0036021	endolysosome lumen(GO:0036021)
2.6	13.1	GO:0097179	protease inhibitor complex(GO:0097179)
2.0	6.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
2.0	11.8	GO:0042825	TAP complex(GO:0042825)
1.7	11.9	GO:0030870	Mre11 complex(GO:0030870)
1.6	12.9	GO:0032010	phagolysosome(GO:0032010)
1.4	5.6	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
1.3	7.8	GO:0008537	proteasome activator complex(GO:0008537)
1.2	8.3	GO:0043196	varicosity(GO:0043196)
1.2	12.8	GO:0042612	MHC class I protein complex(GO:0042612)
1.1	5.4	GO:0071797	LUBAC complex(GO:0071797)
1.0	20.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
1.0	12.5	GO:0008385	IkappaB kinase complex(GO:0008385)
1.0	12.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.8	3.4	GO:0097454	Schwann cell microvillus(GO:0097454)
0.8	4.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.8	5.4	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.6	4.5	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6	6.8	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.6	6.5	GO:0033391	chromatoid body(GO:0033391)
0.6	2.8	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.5	4.9	GO:0035631	CD40 receptor complex(GO:0035631)
0.5	37.9	GO:0015030	Cajal body(GO:0015030)
0.5	1.6	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.4	1.6	GO:0031905	early endosome lumen(GO:0031905)
0.4	29.9	GO:0035577	azurophil granule membrane(GO:0035577)
0.4	1.1	GO:0071748	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.3	4.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.3	1.7	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.3	1.0	GO:0036398	TCR signalosome(GO:0036398)
0.3	0.9	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3	4.6	GO:0005641	nuclear envelope lumen(GO:0005641)
0.3	0.6	GO:0031213	RSF complex(GO:0031213)
0.3	18.6	GO:0005643	nuclear pore(GO:0005643)
0.3	1.3	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.2	5.0	GO:0002080	acrosomal membrane(GO:0002080)
0.2	4.0	GO:0042611	MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
0.2	1.0	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.2	1.5	GO:0005587	collagen type IV trimer(GO:0005587)
0.2	17.3	GO:0018995	host(GO:0018995) host cell(GO:0043657)
0.2	0.5	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	5.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.4	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	1.8	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.1	12.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	5.5	GO:0097542	ciliary tip(GO:0097542)
0.1	5.4	GO:0016235	aggresome(GO:0016235)
0.1	52.2	GO:0016607	nuclear speck(GO:0016607)
0.1	38.9	GO:0031965	nuclear membrane(GO:0031965)
0.1	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.1	12.4	GO:0001650	fibrillar center(GO:0001650)
0.1	0.8	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.9	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.1	1.3	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1	12.7	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.1	2.7	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	29.5	GO:0000790	nuclear chromatin(GO:0000790)
0.1	3.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.6	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	0.5	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	22.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	8.0	GO:0005635	nuclear envelope(GO:0005635)
0.1	1.9	GO:0051233	spindle midzone(GO:0051233)
0.1	0.5	GO:0032009	early phagosome(GO:0032009)
0.1	1.0	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	11.0	GO:0005741	mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.1	4.9	GO:1904724	tertiary granule lumen(GO:1904724)
0.1	0.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	0.5	GO:0005827	polar microtubule(GO:0005827)
0.1	0.7	GO:0031082	BLOC complex(GO:0031082)
0.1	2.8	GO:0031201	SNARE complex(GO:0031201)
0.0	2.1	GO:0001772	immunological synapse(GO:0001772)
0.0	3.6	GO:0043679	axon terminus(GO:0043679)
0.0	0.3	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	0.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	64.6	GO:0005739	mitochondrion(GO:0005739)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	3.5	GO:0030175	filopodium(GO:0030175)
0.0	27.5	GO:0005768	endosome(GO:0005768)
0.0	0.2	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	9.1	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.2	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.6	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	2.1	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	2.5	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	1.6	GO:0034707	chloride channel complex(GO:0034707)
0.0	9.4	GO:0016020	membrane(GO:0016020)
0.0	0.4	GO:0035580	specific granule lumen(GO:0035580)
0.0	2.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.3	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	1.0	GO:0005814	centriole(GO:0005814)
0.0	0.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.8	GO:0000922	spindle pole(GO:0000922)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	99.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
1.8	50.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
1.1	19.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	7.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	4.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	1.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	1.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.5	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	5.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	3.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	0.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	6.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.7	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	7.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	1.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	3.4	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	1.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.6	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.5	3.0	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.5	1.8	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4	4.4	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.2	1.9	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2	1.3	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2	1.4	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2	0.5	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.1	1.0	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	0.3	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1	0.5	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1	0.3	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.9	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.1	2.4	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.3	GO:0007113	endomitotic cell cycle(GO:0007113)
0.1	1.2	GO:1901978	mitochondrial fragmentation involved in apoptotic process(GO:0043653) positive regulation of cell cycle checkpoint(GO:1901978)
0.1	0.5	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	0.4	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1	0.2	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1	0.8	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.6	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.2	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.7	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.4	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.4	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	1.4	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.2	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.1	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.2	GO:2000391	ectopic germ cell programmed cell death(GO:0035234) positive regulation of neutrophil extravasation(GO:2000391)
0.0	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.3	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.1	GO:2000568	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0	0.1	GO:0030828	positive regulation of cGMP metabolic process(GO:0030825) positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.1	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.3	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531)
0.0	0.1	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0	0.4	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.1	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0	0.0	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.0	0.5	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0099525	presynaptic dense core granule exocytosis(GO:0099525)
0.0	0.1	GO:0051036	regulation of endosome size(GO:0051036)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	45.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.6	12.0	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.6	10.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.5	4.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.5	7.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.4	6.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.4	12.6	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.3	10.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3	24.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3	6.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	22.4	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.2	6.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	37.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.2	3.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	3.5	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.1	5.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	1.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	3.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.0	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	5.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	2.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.3	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	7.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	7.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.8	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	1.9	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	0.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	3.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	0.9	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	0.6	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	1.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	3.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.9	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.5	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	2.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	4.4	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	2.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	1.0	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	3.6	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.9	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	1.1	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.5	GO:0097165	nuclear stress granule(GO:0097165)
0.1	0.4	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	4.3	GO:0005844	polysome(GO:0005844)
0.1	0.2	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	0.3	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.1	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.0	0.4	GO:0030914	STAGA complex(GO:0030914)
0.0	0.6	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.4	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.3	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	1.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.4	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.3	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.0	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	3.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	2.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	1.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	2.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.6	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	1.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	2.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.2	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	7.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	4.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.8	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	1.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	3.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.3	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.1	1.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	3.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	3.4	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	3.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.6	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	2.6	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	0.5	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.2	11.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	5.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.6	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	2.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	2.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	1.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	1.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	6.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	4.9	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.4	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	1.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	13.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	4.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.4	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.1	2.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	2.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.1	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.9	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	3.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	3.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	1.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.1	12.4	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.5	9.9	GO:0097325	melanocyte proliferation(GO:0097325)
1.0	8.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.9	2.8	GO:2000097	chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.9	11.3	GO:0001778	plasma membrane repair(GO:0001778)
0.6	5.5	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.6	1.8	GO:0060578	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.6	7.2	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.5	1.6	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.4	1.6	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.4	1.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.3	2.1	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.3	1.0	GO:0060437	lung growth(GO:0060437)
0.3	3.8	GO:0070307	lens fiber cell development(GO:0070307)
0.3	1.4	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.3	2.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3	3.8	GO:0032060	bleb assembly(GO:0032060)
0.2	1.0	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2	1.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.2	0.6	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.2	6.2	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2	0.6	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.2	2.7	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.4	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1	3.3	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.1	0.4	GO:0003408	optic cup formation involved in camera-type eye development(GO:0003408)
0.1	4.6	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.4	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.1	0.4	GO:0002572	pro-T cell differentiation(GO:0002572)
0.1	2.3	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.3	GO:0032661	regulation of interleukin-18 production(GO:0032661) positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1	0.2	GO:0031448	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1	0.2	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.1	2.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.1	1.6	GO:0030728	ovulation(GO:0030728)
0.0	3.5	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	2.0	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	0.3	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.8	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.8	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.9	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	3.0	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.0	1.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	4.2	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.0	0.3	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.3	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.8	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.6	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.7	GO:1901264	carbohydrate derivative transport(GO:1901264)
0.0	0.1	GO:0034334	adherens junction maintenance(GO:0034334)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	39.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	3.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	6.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	3.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.5	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	4.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	2.7	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	1.6	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	2.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	3.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	3.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	0.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.8	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	1.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	6.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.6	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.9	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.8	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.8	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.8	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.4	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.7	66.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
1.7	64.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.4	91.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.9	22.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.9	24.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5	14.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.5	11.8	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.4	6.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3	8.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	15.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.3	1.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	3.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	5.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	4.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	14.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	7.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	3.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	3.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	2.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	7.3	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	1.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	2.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	1.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	3.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	5.6	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.5	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	4.3	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	2.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	5.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	1.4	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	10.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	3.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.9	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	1.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	PID ALK2 PATHWAY	ALK2 signaling events
0.0	2.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	2.1	NABA COLLAGENS	Genes encoding collagen proteins
0.0	3.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.6	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	2.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	2.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	3.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.8	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.8	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	1.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	1.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.6	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	1.2	PID BMP PATHWAY	BMP receptor signaling
0.0	1.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.8	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.4	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	2.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.1	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	2.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.4	66.4	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
4.5	18.0	GO:0030485	smooth muscle contractile fiber(GO:0030485)
3.2	47.3	GO:0030478	actin cap(GO:0030478)
2.8	45.4	GO:0097512	cardiac myofibril(GO:0097512)
2.8	11.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
2.4	7.3	GO:0005588	collagen type V trimer(GO:0005588)
2.4	7.2	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
2.2	29.2	GO:0005577	fibrinogen complex(GO:0005577)
1.8	21.7	GO:0099634	postsynaptic specialization membrane(GO:0099634)
1.4	19.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.4	2.7	GO:1990584	cardiac Troponin complex(GO:1990584)
1.3	5.3	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.1	17.9	GO:0032059	bleb(GO:0032059)
1.0	22.9	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.9	4.4	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.8	48.4	GO:0005801	cis-Golgi network(GO:0005801)
0.8	28.9	GO:0005859	muscle myosin complex(GO:0005859)
0.6	5.4	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.5	2.7	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.4	1.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.3	1.7	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.3	3.3	GO:0005916	fascia adherens(GO:0005916)
0.3	2.6	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.3	7.4	GO:0031143	pseudopodium(GO:0031143)
0.3	4.6	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.3	17.0	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	2.7	GO:0097443	sorting endosome(GO:0097443)
0.2	10.4	GO:0002102	podosome(GO:0002102)
0.2	18.7	GO:0001750	photoreceptor outer segment(GO:0001750)
0.2	0.7	GO:0016600	flotillin complex(GO:0016600)
0.2	1.3	GO:0005610	laminin-5 complex(GO:0005610)
0.2	18.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.2	2.6	GO:0005652	nuclear lamina(GO:0005652)
0.2	5.9	GO:0043034	costamere(GO:0043034)
0.2	2.0	GO:0008091	spectrin(GO:0008091)
0.2	5.7	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	15.6	GO:0030175	filopodium(GO:0030175)
0.1	0.3	GO:0071437	invadopodium(GO:0071437) invadopodium membrane(GO:0071438)
0.1	0.8	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	0.1	GO:0005607	laminin-2 complex(GO:0005607)
0.1	18.4	GO:0031674	I band(GO:0031674)
0.1	1.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	5.0	GO:0016459	myosin complex(GO:0016459)
0.1	12.5	GO:0005923	bicellular tight junction(GO:0005923)
0.1	1.5	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	2.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	1.5	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.7	GO:0043083	synaptic cleft(GO:0043083)
0.1	26.8	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	0.2	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1	0.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	1.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.6	GO:0043198	dendritic shaft(GO:0043198)
0.0	6.2	GO:0005795	Golgi stack(GO:0005795)
0.0	0.4	GO:0005579	membrane attack complex(GO:0005579)
0.0	1.1	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.4	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	3.2	GO:0005811	lipid particle(GO:0005811)
0.0	3.1	GO:0034707	chloride channel complex(GO:0034707)
0.0	3.3	GO:0005882	intermediate filament(GO:0005882)
0.0	1.5	GO:0097546	ciliary base(GO:0097546)
0.0	0.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	4.4	GO:0030427	site of polarized growth(GO:0030427)
0.0	6.4	GO:0072562	blood microparticle(GO:0072562)
0.0	1.5	GO:0005902	microvillus(GO:0005902)
0.0	1.0	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	6.3	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	1.9	GO:0042641	actomyosin(GO:0042641)
0.0	1.3	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.2	GO:1902560	GMP reductase complex(GO:1902560)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	1.3	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	2.2	GO:0005875	microtubule associated complex(GO:0005875)
0.0	0.5	GO:0036379	myofilament(GO:0036379)
0.0	1.0	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.9	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0	5.0	GO:0010008	endosome membrane(GO:0010008)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	2.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.9	32.7	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
5.6	16.9	GO:0008859	exoribonuclease II activity(GO:0008859)
1.7	12.2	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
1.1	7.6	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
1.1	4.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8	4.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.8	3.4	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.7	2.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.7	2.2	GO:0032089	NACHT domain binding(GO:0032089)
0.7	34.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.7	2.0	GO:0061663	NEDD8 ligase activity(GO:0061663)
0.6	3.0	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.6	4.1	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.5	2.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5	4.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.5	3.5	GO:0001515	opioid peptide activity(GO:0001515)
0.5	1.5	GO:0050135	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.5	2.9	GO:0042610	CD8 receptor binding(GO:0042610)
0.5	2.9	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.5	1.9	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5	1.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5	2.7	GO:0042296	ISG15 transferase activity(GO:0042296)
0.4	4.9	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4	6.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.4	2.2	GO:0000298	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.4	1.7	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.4	1.7	GO:0042289	MHC class II protein binding(GO:0042289)
0.4	1.3	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.4	0.4	GO:0050436	microfibril binding(GO:0050436)
0.4	1.6	GO:0019770	IgG receptor activity(GO:0019770)
0.4	2.0	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.4	1.6	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.4	0.8	GO:0030348	syntaxin-3 binding(GO:0030348)
0.4	1.9	GO:0061665	SUMO ligase activity(GO:0061665)
0.4	1.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.4	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.4	1.4	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.4	4.0	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.4	2.8	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3	1.7	GO:1990460	leptin receptor binding(GO:1990460)
0.3	1.4	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3	3.7	GO:0051525	NFAT protein binding(GO:0051525)
0.3	2.4	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3	1.3	GO:0008422	beta-glucuronidase activity(GO:0004566) beta-glucosidase activity(GO:0008422)
0.3	2.3	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.3	1.0	GO:0015235	cobalamin transporter activity(GO:0015235)
0.3	0.9	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3	0.9	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3	1.6	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.3	0.9	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.3	1.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.3	1.2	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3	1.2	GO:0004998	transferrin receptor activity(GO:0004998)
0.3	2.0	GO:0043208	glycosphingolipid binding(GO:0043208)
0.3	0.9	GO:0002134	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.3	1.4	GO:0070905	serine binding(GO:0070905)
0.3	4.0	GO:0030280	structural constituent of epidermis(GO:0030280)
0.3	4.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3	1.1	GO:0004335	galactokinase activity(GO:0004335)
0.3	1.4	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.3	0.8	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.3	1.1	GO:0035473	lipase binding(GO:0035473)
0.3	0.8	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3	1.1	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3	0.8	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3	0.8	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2	0.7	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2	1.5	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2	1.0	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2	0.7	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.2	5.5	GO:0001056	RNA polymerase III activity(GO:0001056)
0.2	1.2	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.2	2.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	1.4	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.2	0.7	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.2	3.2	GO:0004875	complement receptor activity(GO:0004875)
0.2	3.7	GO:0043295	glutathione binding(GO:0043295)
0.2	1.3	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2	0.7	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.2	0.2	GO:0004673	protein histidine kinase activity(GO:0004673)
0.2	3.6	GO:0038191	neuropilin binding(GO:0038191)
0.2	3.6	GO:0019992	diacylglycerol binding(GO:0019992)
0.2	1.5	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2	1.5	GO:0042608	T cell receptor binding(GO:0042608)
0.2	0.6	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2	0.8	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.2	0.6	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.2	0.6	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.2	1.0	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2	1.7	GO:0015926	glucosidase activity(GO:0015926)
0.2	1.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.2	0.7	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2	0.9	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.2	1.7	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	1.1	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.2	4.4	GO:0071837	HMG box domain binding(GO:0071837)
0.2	1.8	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2	0.5	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.2	1.8	GO:0048406	nerve growth factor binding(GO:0048406)
0.2	0.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.2	1.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2	1.2	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.2	0.5	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.2	0.5	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2	2.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	0.7	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.2	2.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.2	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.2	0.5	GO:0000035	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.2	0.5	GO:0008502	melatonin receptor activity(GO:0008502)
0.2	1.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.2	0.5	GO:0031859	platelet activating factor receptor binding(GO:0031859)
0.2	0.5	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2	1.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.1	3.0	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.7	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	3.9	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.4	GO:0031877	somatostatin receptor binding(GO:0031877)
0.1	0.4	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	0.3	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1	0.4	GO:0008941	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1	0.4	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	1.4	GO:0051425	PTB domain binding(GO:0051425)
0.1	0.8	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	3.9	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.4	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	2.7	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.7	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	0.4	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1	0.8	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.5	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.4	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	0.9	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.6	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	1.4	GO:0097016	L27 domain binding(GO:0097016)
0.1	1.1	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.5	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.4	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.5	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.1	2.7	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	2.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	3.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	5.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.8	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.9	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	1.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.7	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.6	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	0.4	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.1	0.9	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.4	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1	1.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.6	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.3	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1	0.3	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.1	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.1	0.4	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1	0.6	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	1.0	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	1.2	GO:0032027	myosin light chain binding(GO:0032027)
0.1	3.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	1.4	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	0.7	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1	0.3	GO:0017129	triglyceride binding(GO:0017129)
0.1	0.6	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.5	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.5	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.1	0.1	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.1	0.4	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1	0.3	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	0.5	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	1.0	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	1.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.6	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.1	0.7	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	3.9	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	0.5	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	14.7	GO:0003823	antigen binding(GO:0003823)
0.1	0.5	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.7	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	1.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	1.0	GO:0016502	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.1	0.3	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.9	GO:0001055	RNA polymerase II activity(GO:0001055)
0.1	0.4	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.8	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.8	GO:0004969	histamine receptor activity(GO:0004969)
0.1	1.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.3	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	0.3	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1	2.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.5	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	2.6	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	1.8	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.4	GO:0047820	D-glutamate cyclase activity(GO:0047820)
0.1	0.4	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.1	4.1	GO:0070888	E-box binding(GO:0070888)
0.1	0.2	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.1	0.2	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.1	0.6	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1	0.5	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.4	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.4	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	0.3	GO:0036033	mediator complex binding(GO:0036033)
0.1	1.0	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.1	0.2	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.8	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.8	GO:0015232	heme transporter activity(GO:0015232)
0.1	0.4	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.5	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.6	GO:0034711	inhibin binding(GO:0034711)
0.1	0.3	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	1.6	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	2.0	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	1.8	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.5	GO:0039706	co-receptor binding(GO:0039706)
0.1	0.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	1.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	1.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.1	1.4	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1	0.6	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.3	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1	1.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.2	GO:0052870	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1	0.2	GO:0035591	signaling adaptor activity(GO:0035591)
0.1	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.1	1.2	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.3	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	3.0	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	1.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.9	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.5	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1	0.7	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	1.0	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.4	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	1.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.3	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	1.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	0.6	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.1	0.2	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	0.2	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.1	2.2	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.1	1.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	1.7	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	1.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.2	GO:0035939	microsatellite binding(GO:0035939)
0.1	1.4	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	0.5	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.6	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	0.4	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.2	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1	1.5	GO:0005123	death receptor binding(GO:0005123)
0.1	15.7	GO:0003714	transcription corepressor activity(GO:0003714)
0.1	0.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.1	GO:0004040	amidase activity(GO:0004040)
0.1	0.2	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.4	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1	0.3	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	5.3	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.1	0.2	GO:0042020	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1	0.5	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.4	GO:0003951	NAD+ kinase activity(GO:0003951)
0.1	0.6	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.2	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	0.4	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	0.5	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.4	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	0.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.2	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.2	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	0.2	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.3	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	1.4	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.0	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.0	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.8	GO:0005537	mannose binding(GO:0005537)
0.0	0.6	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.4	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.4	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.9	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	1.3	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
0.0	0.2	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.2	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.0	0.7	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.6	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.6	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	0.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.4	GO:0030552	cAMP binding(GO:0030552)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.3	GO:0045159	myosin II binding(GO:0045159)
0.0	0.5	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.9	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.8	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.5	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.3	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	0.9	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.5	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	3.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.3	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	1.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.7	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	1.2	GO:0001046	core promoter sequence-specific DNA binding(GO:0001046)
0.0	0.4	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.4	GO:0032052	bile acid binding(GO:0032052)
0.0	0.4	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.7	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.4	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.8	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	1.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.3	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.6	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.6	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.3	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.0	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.8	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0008480	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	0.3	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.4	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	3.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.7	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.2	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.4	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.3	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.2	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.6	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	18.2	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0	0.6	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.5	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.2	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.5	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.4	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.4	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.4	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.5	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.4	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	1.7	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.0	2.6	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	1.0	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	1.7	GO:0008186	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0	0.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	2.2	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.2	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.8	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.1	GO:0034594	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0	0.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.2	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.6	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.8	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.4	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.5	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.6	GO:0031489	myosin V binding(GO:0031489)
0.0	0.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.5	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.0	5.1	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.4	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	1.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0	0.1	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.5	GO:0016741	transferase activity, transferring one-carbon groups(GO:0016741)
0.0	2.7	GO:0001067	regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.6	GO:0002039	p53 binding(GO:0002039)
0.0	0.3	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.9	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0045125	sphingosine-1-phosphate receptor activity(GO:0038036) bioactive lipid receptor activity(GO:0045125)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.4	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.4	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.4	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.0	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.3	GO:0008187	poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0	0.4	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0019843	rRNA binding(GO:0019843)
0.0	0.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.9	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.1	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.3	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.4	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	0.3	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.3	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.0	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.0	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.1	GO:0019865	immunoglobulin binding(GO:0019865)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	2.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	2.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.7	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.5	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.9	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	2.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	4.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.8	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.5	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	9.8	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.6	6.1	GO:0031013	troponin I binding(GO:0031013)
0.4	1.7	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4	1.1	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2	0.7	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.2	2.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.2	0.7	GO:0070699	type II activin receptor binding(GO:0070699)
0.2	0.7	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.2	21.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	0.4	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.2	0.6	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	1.1	GO:0004111	creatine kinase activity(GO:0004111)
0.1	2.7	GO:0016805	dipeptidase activity(GO:0016805)
0.1	1.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	3.0	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.4	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	0.5	GO:0016972	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1	0.6	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	0.8	GO:0071253	connexin binding(GO:0071253)
0.1	0.4	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	1.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.5	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	0.5	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	2.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	0.3	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.9	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	12.2	GO:0005178	integrin binding(GO:0005178)
0.1	1.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	1.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	0.7	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	7.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	1.8	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.5	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	1.1	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.7	GO:0008494	translation activator activity(GO:0008494)
0.0	3.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.4	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	1.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	5.2	GO:0044325	ion channel binding(GO:0044325)
0.0	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	1.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	1.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.4	GO:0008301	four-way junction DNA binding(GO:0000400) DNA binding, bending(GO:0008301)
0.0	0.3	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0000217	DNA secondary structure binding(GO:0000217)
0.0	0.2	GO:0032190	acrosin binding(GO:0032190)
0.0	1.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.3	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	2.5	GO:0008201	heparin binding(GO:0008201)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	2.4	GO:0051015	actin filament binding(GO:0051015)
0.0	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	1.2	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.0	GO:0031852	mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	0.6	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0005960	glycine cleavage complex(GO:0005960)
0.4	2.6	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.3	7.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	2.6	GO:0005577	fibrinogen complex(GO:0005577)
0.2	3.1	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.4	GO:0070195	growth hormone receptor complex(GO:0070195)
0.1	2.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.5	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	0.7	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.3	GO:0032279	asymmetric synapse(GO:0032279)
0.1	0.3	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.1	1.0	GO:0031209	SCAR complex(GO:0031209)
0.1	1.1	GO:0097342	ripoptosome(GO:0097342)
0.0	0.2	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.3	GO:0032437	cuticular plate(GO:0032437)
0.0	7.8	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.7	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.3	GO:0000796	condensin complex(GO:0000796)
0.0	0.7	GO:0032040	small-subunit processome(GO:0032040)
0.0	3.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	2.3	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.6	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.0	1.7	GO:0016605	PML body(GO:0016605)
0.0	1.7	GO:0043679	axon terminus(GO:0043679)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.6	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	0.6	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	10.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	3.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	0.9	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	3.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	2.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	3.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	4.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	4.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.9	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.8	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	2.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	3.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.6	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.7	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.3	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.2	REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX	Genes involved in Assembly of the pre-replicative complex

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	15.4	GO:0030421	defecation(GO:0030421)
1.6	12.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
1.3	1.3	GO:0043485	endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
1.3	3.8	GO:1900158	negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.2	5.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
1.2	3.7	GO:1900073	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
1.1	3.3	GO:0090427	activation of meiosis(GO:0090427)
1.1	4.3	GO:0035026	leading edge cell differentiation(GO:0035026)
1.0	3.0	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.9	3.8	GO:1902613	regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.9	4.7	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.9	4.5	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.8	4.9	GO:0061441	renal artery morphogenesis(GO:0061441)
0.8	2.5	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.8	2.4	GO:0061760	antifungal innate immune response(GO:0061760)
0.8	0.8	GO:0021569	rhombomere 3 development(GO:0021569)
0.8	3.1	GO:1904565	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.7	3.0	GO:1904978	regulation of endosome organization(GO:1904978)
0.7	2.2	GO:0061188	negative regulation of chromatin silencing at rDNA(GO:0061188)
0.7	2.8	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.7	4.1	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7	4.0	GO:0010748	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.7	0.7	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.7	2.6	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.7	3.3	GO:0044855	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.6	0.6	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.6	3.2	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.6	0.6	GO:0031133	regulation of axon diameter(GO:0031133)
0.6	5.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.6	1.9	GO:0007037	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.6	2.4	GO:0021564	vagus nerve development(GO:0021564)
0.6	2.4	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.6	1.2	GO:0007412	axon target recognition(GO:0007412)
0.6	0.6	GO:0090102	cochlea development(GO:0090102)
0.6	2.4	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.6	1.8	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.6	2.9	GO:0030047	actin modification(GO:0030047)
0.6	3.5	GO:0090131	mesenchyme migration(GO:0090131)
0.5	3.8	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.5	0.5	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.5	1.6	GO:0010710	regulation of collagen catabolic process(GO:0010710)
0.5	2.1	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.5	3.2	GO:0052551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.5	2.7	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.5	2.1	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.5	1.6	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.5	1.6	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.5	2.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.5	4.6	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.5	1.5	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5	4.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.5	1.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.5	1.5	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.5	0.5	GO:1903384	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.5	1.5	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.5	2.5	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.5	1.5	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.5	1.5	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.5	2.9	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.5	0.5	GO:1990502	dense core granule maturation(GO:1990502)
0.5	4.8	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.5	3.3	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.5	1.9	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.5	1.4	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.5	14.0	GO:2001044	regulation of integrin-mediated signaling pathway(GO:2001044)
0.5	0.9	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.5	1.4	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5	1.4	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.5	1.4	GO:0061386	closure of optic fissure(GO:0061386)
0.5	0.5	GO:0007567	parturition(GO:0007567)
0.4	2.2	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.4	1.3	GO:0072244	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.4	8.1	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.4	1.8	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.4	0.4	GO:0097485	neuron projection guidance(GO:0097485)
0.4	0.4	GO:0097324	melanocyte migration(GO:0097324)
0.4	6.7	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.4	1.3	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.4	1.3	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.4	2.6	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.4	5.2	GO:0045794	negative regulation of cell volume(GO:0045794)
0.4	2.1	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4	1.7	GO:1904529	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.4	1.3	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.4	1.7	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.4	1.2	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4	0.8	GO:0097477	spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.4	4.5	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.4	1.7	GO:0060434	bronchus morphogenesis(GO:0060434)
0.4	1.6	GO:2000035	regulation of stem cell division(GO:2000035)
0.4	2.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4	0.4	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.4	1.6	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.4	0.4	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.4	1.2	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.4	1.2	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4	3.6	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.4	1.6	GO:1904753	negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.4	1.2	GO:0021592	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.4	1.2	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.4	1.1	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.4	1.1	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.4	1.9	GO:0000189	MAPK import into nucleus(GO:0000189)
0.4	1.1	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.4	3.4	GO:0044857	plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.4	2.7	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.4	1.1	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.4	2.3	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.4	2.2	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.4	1.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4	4.8	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.4	1.1	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.4	1.8	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.4	0.7	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4	3.3	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.4	1.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.4	0.4	GO:0035973	aggrephagy(GO:0035973)
0.4	3.3	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.4	1.4	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.4	4.6	GO:0032060	bleb assembly(GO:0032060)
0.4	1.4	GO:0071492	cellular response to UV-A(GO:0071492)
0.4	1.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.3	3.1	GO:0001887	selenium compound metabolic process(GO:0001887)
0.3	0.3	GO:0061042	vascular wound healing(GO:0061042)
0.3	2.7	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.3	0.3	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.3	0.3	GO:2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.3	1.0	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.3	1.0	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.3	1.7	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.3	1.7	GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.3	1.3	GO:0046086	adenosine biosynthetic process(GO:0046086)
0.3	1.0	GO:0098968	neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.3	3.2	GO:1900223	positive regulation of beta-amyloid clearance(GO:1900223)
0.3	5.8	GO:0070208	protein heterotrimerization(GO:0070208)
0.3	0.3	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.3	1.3	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.3	1.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	1.6	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3	0.3	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.3	0.3	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.3	1.3	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.3	1.9	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.3	3.7	GO:0043102	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.3	3.4	GO:0006621	protein retention in ER lumen(GO:0006621)
0.3	0.3	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3	0.9	GO:0032242	regulation of nucleoside transport(GO:0032242)
0.3	0.9	GO:0019417	sulfur oxidation(GO:0019417)
0.3	1.5	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3	0.9	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3	0.3	GO:0051795	positive regulation of catagen(GO:0051795)
0.3	1.8	GO:0072719	cellular response to cisplatin(GO:0072719)
0.3	0.9	GO:1904815	negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.3	1.2	GO:0009956	radial pattern formation(GO:0009956)
0.3	0.6	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.3	1.2	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.3	0.9	GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.3	1.2	GO:0070141	response to UV-A(GO:0070141)
0.3	1.2	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.3	0.9	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.3	1.5	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3	0.9	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.3	0.6	GO:0033594	response to hydroxyisoflavone(GO:0033594)
0.3	0.6	GO:0060352	cell adhesion molecule production(GO:0060352)
0.3	1.8	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.3	0.3	GO:0072497	mesenchymal stem cell differentiation(GO:0072497)
0.3	1.7	GO:0006561	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3	0.3	GO:0032310	prostaglandin secretion(GO:0032310)
0.3	0.9	GO:0007518	myoblast fate determination(GO:0007518)
0.3	0.8	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.3	0.8	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
0.3	1.1	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.3	0.6	GO:0007439	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.3	1.1	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.3	1.4	GO:0046898	response to cycloheximide(GO:0046898)
0.3	1.1	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.3	1.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.3	1.4	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.3	1.4	GO:0003070	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3	0.6	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.3	0.8	GO:0003350	pulmonary myocardium development(GO:0003350) subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3	1.4	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.3	0.8	GO:0035378	carbon dioxide transmembrane transport(GO:0035378)
0.3	4.1	GO:0051764	actin crosslink formation(GO:0051764)
0.3	0.8	GO:2000910	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.3	0.8	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3	1.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.3	1.4	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.3	2.2	GO:0015693	magnesium ion transport(GO:0015693)
0.3	1.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.3	0.8	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.3	0.3	GO:0060056	mammary gland involution(GO:0060056)
0.3	1.6	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.3	1.6	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.3	0.5	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.3	0.3	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.3	0.8	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3	1.3	GO:1990504	dense core granule exocytosis(GO:1990504)
0.3	2.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3	1.0	GO:0006850	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.3	1.3	GO:0097168	mesenchymal stem cell proliferation(GO:0097168)
0.3	1.0	GO:0032218	riboflavin transport(GO:0032218)
0.3	0.5	GO:0051462	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.3	0.8	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3	0.8	GO:0032025	response to cobalt ion(GO:0032025)
0.3	0.3	GO:0009838	abscission(GO:0009838)
0.3	0.5	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.3	1.8	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.3	0.8	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3	3.3	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.3	4.3	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.3	1.8	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2	0.7	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.2	1.2	GO:1903974	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.2	0.7	GO:0042117	monocyte activation(GO:0042117)
0.2	0.5	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.2	0.2	GO:0016082	synaptic vesicle priming(GO:0016082)
0.2	1.0	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2	2.0	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.2	0.2	GO:0070986	left/right axis specification(GO:0070986)
0.2	0.2	GO:0072103	glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2	2.4	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2	0.5	GO:0097212	lysosomal membrane organization(GO:0097212)
0.2	0.5	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2	0.2	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2	0.2	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2	0.7	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.2	1.2	GO:0097338	response to clozapine(GO:0097338)
0.2	1.2	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.2	0.7	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2	1.0	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.2	0.2	GO:0015677	copper ion import(GO:0015677)
0.2	0.2	GO:0072425	signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.2	1.2	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2	0.9	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.2	0.9	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.2	0.7	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.2	5.8	GO:0008045	motor neuron axon guidance(GO:0008045)
0.2	1.8	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2	0.2	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.2	1.1	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.2	0.7	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.2	1.6	GO:0032288	myelin assembly(GO:0032288)
0.2	5.7	GO:0006068	ethanol catabolic process(GO:0006068)
0.2	1.3	GO:0033216	ferric iron import(GO:0033216)
0.2	2.5	GO:0072505	phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)
0.2	0.7	GO:0032474	otolith morphogenesis(GO:0032474)
0.2	0.9	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.2	0.2	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2	1.6	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2	2.0	GO:0001778	plasma membrane repair(GO:0001778)
0.2	0.2	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.2	0.2	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2	0.9	GO:0016333	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.2	1.7	GO:0008090	retrograde axonal transport(GO:0008090)
0.2	1.5	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
0.2	0.9	GO:0045218	zonula adherens maintenance(GO:0045218)
0.2	1.3	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2	1.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.2	0.4	GO:0015960	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.2	0.6	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2	0.2	GO:0090109	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.2	0.6	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.2	1.1	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.2	0.6	GO:0000050	urea cycle(GO:0000050)
0.2	2.3	GO:0046325	negative regulation of glucose import(GO:0046325)
0.2	1.5	GO:0046485	ether lipid metabolic process(GO:0046485)
0.2	1.7	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.2	0.8	GO:0021561	facial nerve development(GO:0021561) facial nerve morphogenesis(GO:0021610)
0.2	0.6	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2	0.2	GO:0002418	immune response to tumor cell(GO:0002418)
0.2	0.6	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.2	0.8	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	1.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2	0.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.2	0.2	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.2	0.4	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2	1.4	GO:0042126	nitrate metabolic process(GO:0042126)
0.2	0.6	GO:0003064	regulation of heart rate by hormone(GO:0003064)
0.2	0.2	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.2	0.8	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.2	1.0	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2	0.2	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.2	0.4	GO:0086053	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2	0.6	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.2	0.4	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.2	0.8	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.2	0.8	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2	0.8	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.2	0.6	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2	2.2	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	1.4	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.2	0.6	GO:0060296	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2	1.0	GO:0015692	lead ion transport(GO:0015692)
0.2	2.7	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.2	0.6	GO:0043418	homocysteine catabolic process(GO:0043418)
0.2	1.9	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.2	3.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.2	0.6	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.2	0.9	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.2	0.6	GO:0042412	taurine biosynthetic process(GO:0042412)
0.2	1.9	GO:0000052	citrulline metabolic process(GO:0000052)
0.2	0.4	GO:0061010	gall bladder development(GO:0061010)
0.2	0.7	GO:0070981	L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.2	0.2	GO:0006041	glucosamine metabolic process(GO:0006041)
0.2	0.6	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.2	0.9	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2	2.6	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.2	2.0	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.2	0.6	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2	1.3	GO:0010044	response to aluminum ion(GO:0010044)
0.2	0.2	GO:0009186	nucleoside diphosphate biosynthetic process(GO:0009133) deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2	0.6	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2	2.0	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2	1.8	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	2.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2	1.3	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.2	1.1	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.2	1.8	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	1.8	GO:0010265	SCF complex assembly(GO:0010265)
0.2	1.3	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
0.2	0.2	GO:0010637	regulation of mitochondrial fusion(GO:0010635) negative regulation of mitochondrial fusion(GO:0010637)
0.2	0.9	GO:0019323	pentose catabolic process(GO:0019323)
0.2	3.2	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.2	0.7	GO:0017198	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2	0.9	GO:0015862	uridine transport(GO:0015862)
0.2	0.9	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.2	0.9	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.2	4.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.2	7.6	GO:0035329	hippo signaling(GO:0035329)
0.2	0.7	GO:0007296	vitellogenesis(GO:0007296)
0.2	0.3	GO:0021558	trochlear nerve development(GO:0021558)
0.2	0.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	1.4	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.2	2.8	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2	1.0	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.2	0.5	GO:0031291	Ran protein signal transduction(GO:0031291)
0.2	2.8	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.2	1.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.2	0.5	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.2	3.3	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.2	0.5	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.2	1.2	GO:0023041	neuronal signal transduction(GO:0023041)
0.2	1.9	GO:0061635	regulation of protein complex stability(GO:0061635)
0.2	0.3	GO:0070781	response to biotin(GO:0070781)
0.2	1.7	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.2	0.7	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2	0.8	GO:0097646	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	0.7	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.2	1.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.2	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.2	0.7	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2	0.3	GO:0044805	late nucleophagy(GO:0044805)
0.2	1.7	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.2	0.2	GO:0060018	astrocyte fate commitment(GO:0060018)
0.2	0.3	GO:0043696	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2	0.5	GO:0098722	asymmetric stem cell division(GO:0098722)
0.2	0.3	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.2	0.7	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2	0.7	GO:0046502	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.2	2.5	GO:0031033	myosin filament organization(GO:0031033)
0.2	0.5	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.2	0.2	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.2	0.2	GO:0072277	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2	0.5	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.2	0.5	GO:0086100	endothelin receptor signaling pathway(GO:0086100)
0.2	1.3	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2	2.6	GO:0090103	cochlea morphogenesis(GO:0090103)
0.2	0.3	GO:0001880	Mullerian duct regression(GO:0001880)
0.2	0.2	GO:0003197	endocardial cushion development(GO:0003197)
0.2	7.8	GO:0003009	skeletal muscle contraction(GO:0003009)
0.2	0.3	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.2	0.5	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.2	2.7	GO:0033622	integrin activation(GO:0033622)
0.2	0.2	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671)
0.2	0.5	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2	0.5	GO:0097359	UDP-glucosylation(GO:0097359)
0.2	0.5	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.2	0.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.2	1.1	GO:0035493	SNARE complex assembly(GO:0035493)
0.2	0.5	GO:0060068	vagina development(GO:0060068)
0.2	0.5	GO:0071529	cementum mineralization(GO:0071529)
0.2	0.8	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.2	1.7	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.2	0.5	GO:0075071	autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.2	0.3	GO:0060022	hard palate development(GO:0060022)
0.1	0.6	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1	2.2	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	9.4	GO:0030574	collagen catabolic process(GO:0030574)
0.1	1.6	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.9	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.1	0.3	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1	2.2	GO:0071711	basement membrane organization(GO:0071711)
0.1	2.0	GO:0006465	signal peptide processing(GO:0006465)
0.1	0.3	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.4	GO:0060406	positive regulation of penile erection(GO:0060406)
0.1	0.3	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.3	GO:0010586	miRNA metabolic process(GO:0010586)
0.1	0.1	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	0.3	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1	0.9	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.4	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.1	1.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	2.1	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.1	0.3	GO:0060221	retinal rod cell differentiation(GO:0060221)
0.1	0.3	GO:0051582	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.3	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.1	1.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.1	1.5	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.6	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	1.4	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.7	GO:0007521	muscle cell fate determination(GO:0007521)
0.1	0.6	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	1.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.1	1.1	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.1	2.9	GO:0065005	protein-lipid complex assembly(GO:0065005)
0.1	0.3	GO:0070541	response to platinum ion(GO:0070541)
0.1	0.8	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.4	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1	0.3	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.1	0.4	GO:0006172	ADP biosynthetic process(GO:0006172)
0.1	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.1	0.4	GO:0001928	regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.1	0.9	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.1	4.2	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	0.3	GO:1901899	positive regulation of relaxation of cardiac muscle(GO:1901899)
0.1	0.4	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.1	0.7	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.5	GO:0006740	NADPH regeneration(GO:0006740)
0.1	0.9	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.1	GO:0098917	retrograde trans-synaptic signaling(GO:0098917)
0.1	0.7	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1	2.8	GO:0061157	mRNA destabilization(GO:0061157)
0.1	0.3	GO:0030242	pexophagy(GO:0030242)
0.1	0.8	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	1.5	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	0.3	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.1	0.7	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1	0.5	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.5	GO:0042713	sperm ejaculation(GO:0042713)
0.1	0.9	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.7	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1	0.5	GO:1901804	glucosylceramide catabolic process(GO:0006680) termination of signal transduction(GO:0023021) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	1.0	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.1	1.8	GO:0048011	neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1	0.9	GO:0008218	bioluminescence(GO:0008218)
0.1	0.1	GO:0032239	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.1	0.9	GO:0046710	GDP metabolic process(GO:0046710)
0.1	6.1	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.3	GO:0060168	positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1	0.8	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.1	0.4	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.1	0.3	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.6	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.8	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.6	GO:0035617	stress granule disassembly(GO:0035617)
0.1	1.9	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	1.3	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	1.4	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.9	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	2.3	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	1.4	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.1	0.4	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.6	GO:0030070	insulin processing(GO:0030070)
0.1	0.2	GO:0045819	positive regulation of glycogen catabolic process(GO:0045819)
0.1	0.5	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.2	GO:0031938	regulation of chromatin silencing at telomere(GO:0031938)
0.1	0.6	GO:0050668	cellular response to phosphate starvation(GO:0016036) regulation of sulfur amino acid metabolic process(GO:0031335) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) regulation of homocysteine metabolic process(GO:0050666) positive regulation of homocysteine metabolic process(GO:0050668)
0.1	0.1	GO:2000381	negative regulation of mesoderm development(GO:2000381)
0.1	1.4	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.1	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661)
0.1	0.1	GO:0021861	forebrain radial glial cell differentiation(GO:0021861)
0.1	0.6	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.2	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.1	0.5	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1	0.8	GO:0060591	chondroblast differentiation(GO:0060591)
0.1	2.2	GO:0099500	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1	0.4	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.2	GO:1901563	response to camptothecin(GO:1901563)
0.1	0.2	GO:1902949	positive regulation of tau-protein kinase activity(GO:1902949)
0.1	0.6	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	1.2	GO:0016540	protein autoprocessing(GO:0016540)
0.1	1.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.7	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	0.1	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	2.4	GO:0046688	response to copper ion(GO:0046688)
0.1	0.2	GO:0060179	male mating behavior(GO:0060179)
0.1	0.5	GO:1904322	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	0.8	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.7	GO:1902306	negative regulation of sodium ion transport(GO:0010766) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1	0.5	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.1	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	2.7	GO:0044458	motile cilium assembly(GO:0044458)
0.1	2.3	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	2.0	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.3	GO:0071934	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1	1.5	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.1	0.3	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.1	0.5	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.1	1.3	GO:0060033	anatomical structure regression(GO:0060033)
0.1	0.8	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.1	0.3	GO:0006478	peptidyl-tyrosine sulfation(GO:0006478)
0.1	0.3	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.1	0.3	GO:0018008	N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.1	0.5	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	1.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.1	0.5	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.1	0.5	GO:0010814	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1	1.0	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	0.7	GO:0060157	urinary bladder development(GO:0060157)
0.1	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.4	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.1	0.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.1	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.2	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.1	0.1	GO:1904030	negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1	0.6	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	1.9	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	1.3	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1	0.4	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.1	0.5	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.4	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.1	0.3	GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1	0.3	GO:0044837	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1	1.8	GO:0009437	carnitine metabolic process(GO:0009437)
0.1	0.7	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.1	1.2	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.1	0.3	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.1	0.1	GO:0045829	negative regulation of isotype switching(GO:0045829)
0.1	0.2	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.1	1.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0014806	smooth muscle hyperplasia(GO:0014806)
0.1	0.4	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	1.3	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1	2.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	1.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.1	0.5	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.1	0.2	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	0.1	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1	0.7	GO:0090042	tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.1	0.3	GO:0045210	FasL biosynthetic process(GO:0045210)
0.1	1.7	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1	0.3	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
0.1	0.2	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.1	0.3	GO:0051013	microtubule severing(GO:0051013)
0.1	0.1	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.1	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	0.6	GO:0046208	spermine catabolic process(GO:0046208)
0.1	0.1	GO:1904933	regulation of cell proliferation in midbrain(GO:1904933)
0.1	0.2	GO:0002839	positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.7	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	0.2	GO:0097056	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1	1.1	GO:0036120	response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1	0.4	GO:2001153	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1	0.3	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1	0.4	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1	1.5	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1	0.2	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.1	0.1	GO:0035350	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1	0.4	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.3	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.1	0.7	GO:0055013	cardiac muscle cell development(GO:0055013)
0.1	0.8	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.1	0.2	GO:0003220	left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.1	0.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1	0.3	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.1	0.9	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.1	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	0.7	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.1	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.1	0.3	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	1.1	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.9	GO:0009650	UV protection(GO:0009650)
0.1	0.5	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	0.4	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.2	GO:0050748	negative regulation of lipoprotein metabolic process(GO:0050748)
0.1	0.2	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1	0.4	GO:0046035	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.6	GO:0036111	very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1	0.2	GO:1900193	regulation of oocyte maturation(GO:1900193)
0.1	0.2	GO:0051031	tRNA transport(GO:0051031)
0.1	0.6	GO:1904376	negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1	2.8	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	0.4	GO:0015816	glycine transport(GO:0015816)
0.1	0.6	GO:0003096	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1	0.1	GO:0030820	regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
0.1	0.3	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.1	4.0	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.1	0.1	GO:0090345	cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1	0.5	GO:0016926	protein desumoylation(GO:0016926)
0.1	0.3	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.1	0.2	GO:0048266	behavioral response to pain(GO:0048266)
0.1	0.3	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1	0.2	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1	1.1	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.1	0.6	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.4	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.1	0.7	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.2	GO:0006404	RNA import into nucleus(GO:0006404)
0.1	0.5	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	1.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.3	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	0.1	GO:1902490	regulation of sperm capacitation(GO:1902490)
0.1	0.2	GO:0030431	sleep(GO:0030431)
0.1	0.3	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.3	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.4	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.1	0.4	GO:1901098	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1	0.3	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.1	0.1	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.1	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1	0.3	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.4	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.3	GO:1904199	positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.1	0.1	GO:1990523	bone regeneration(GO:1990523)
0.1	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.1	GO:0070914	UV-damage excision repair(GO:0070914)
0.1	0.3	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	2.5	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	0.6	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.1	1.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.5	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.1	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.1	0.2	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.1	0.2	GO:0009080	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.1	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.1	0.3	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.1	2.9	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.1	1.4	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1	1.1	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.1	0.5	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.4	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.3	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.1	0.5	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1	1.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.1	0.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.1	0.3	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1	0.7	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.1	1.2	GO:0000338	protein deneddylation(GO:0000338)
0.1	0.9	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.4	GO:0044803	multi-organism membrane organization(GO:0044803)
0.1	1.4	GO:0031643	positive regulation of myelination(GO:0031643)
0.1	0.3	GO:0042473	outer ear morphogenesis(GO:0042473)
0.1	0.1	GO:0044259	multicellular organismal macromolecule metabolic process(GO:0044259)
0.1	0.4	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.6	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.7	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.1	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.1	0.2	GO:0035900	response to isolation stress(GO:0035900)
0.1	0.6	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	0.2	GO:0051705	multi-organism behavior(GO:0051705)
0.1	2.6	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	0.3	GO:0048749	compound eye development(GO:0048749)
0.1	2.9	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	1.4	GO:0031112	positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.1	0.2	GO:0009957	epidermal cell fate specification(GO:0009957)
0.1	0.2	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.1	0.1	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.1	0.2	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.2	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.1	2.0	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.3	GO:1901889	negative regulation of cell junction assembly(GO:1901889)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.2	GO:0016999	antibiotic metabolic process(GO:0016999)
0.1	0.3	GO:0033005	positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.1	0.1	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.6	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.1	0.3	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.1	0.7	GO:0042730	fibrinolysis(GO:0042730)
0.1	0.8	GO:0031000	response to caffeine(GO:0031000)
0.1	0.7	GO:0030091	protein repair(GO:0030091)
0.1	0.5	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.1	0.3	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.1	0.5	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.1	0.2	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1	0.3	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.1	0.3	GO:0090166	Golgi disassembly(GO:0090166)
0.1	0.2	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.2	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.1	0.3	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1	0.5	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	0.2	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1	1.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	0.8	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	0.4	GO:0010731	protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1	0.8	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	2.9	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.1	GO:0030517	negative regulation of axon extension(GO:0030517)
0.1	0.4	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.1	0.1	GO:2000157	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1	0.1	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1	0.7	GO:0035904	aorta development(GO:0035904)
0.1	0.4	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.1	GO:0042048	olfactory behavior(GO:0042048)
0.1	0.2	GO:0080184	response to phenylpropanoid(GO:0080184)
0.1	0.4	GO:0042376	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	0.6	GO:0006623	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623)
0.1	0.9	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.2	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.5	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	0.4	GO:0071873	response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.1	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.2	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1	0.7	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.2	GO:0048747	muscle fiber development(GO:0048747)
0.1	0.4	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1	0.6	GO:0042761	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.1	0.3	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1	0.3	GO:0036152	phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1	0.2	GO:1904046	negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1	0.4	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.4	GO:0001692	histamine metabolic process(GO:0001692)
0.1	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1	0.3	GO:0061744	motor behavior(GO:0061744)
0.1	0.1	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1	0.3	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
0.1	0.4	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.1	0.5	GO:0043586	tongue development(GO:0043586)
0.1	0.3	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.1	2.5	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	0.3	GO:0032364	oxygen homeostasis(GO:0032364)
0.1	0.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	1.2	GO:0007035	vacuolar acidification(GO:0007035)
0.1	0.5	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.1	0.7	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	0.4	GO:0030913	paranodal junction assembly(GO:0030913)
0.1	0.3	GO:1904970	brush border assembly(GO:1904970)
0.1	0.2	GO:0048550	negative regulation of pinocytosis(GO:0048550) regulation of secretion of lysosomal enzymes(GO:0090182) negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1	1.8	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	1.1	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.1	1.8	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.1	0.5	GO:1903393	positive regulation of adherens junction organization(GO:1903393)
0.1	1.6	GO:0033762	response to glucagon(GO:0033762)
0.1	0.1	GO:0036216	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	0.8	GO:0015671	oxygen transport(GO:0015671)
0.1	2.7	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1	0.3	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.1	0.1	GO:0070472	regulation of uterine smooth muscle contraction(GO:0070472)
0.1	1.6	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1	0.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.1	0.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1	0.3	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	0.3	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.1	0.4	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
0.1	0.3	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1	10.0	GO:0043488	regulation of mRNA stability(GO:0043488)
0.1	0.4	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.1	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1	0.6	GO:0034205	beta-amyloid formation(GO:0034205)
0.1	0.2	GO:0050917	sensory perception of umami taste(GO:0050917)
0.1	0.4	GO:0090344	negative regulation of cell aging(GO:0090344)
0.1	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	1.8	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.1	0.3	GO:0006710	androgen catabolic process(GO:0006710)
0.1	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.1	0.4	GO:0006545	glycine biosynthetic process(GO:0006545)
0.1	0.1	GO:1904386	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1	0.1	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.1	2.6	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	0.3	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	0.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.1	0.1	GO:0060923	cardiac muscle cell fate commitment(GO:0060923)
0.1	1.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	0.4	GO:0051012	microtubule sliding(GO:0051012)
0.1	0.1	GO:0048852	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.1	0.4	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.2	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.1	0.9	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.1	0.6	GO:0015886	heme transport(GO:0015886)
0.1	0.4	GO:0032275	luteinizing hormone secretion(GO:0032275)
0.1	0.9	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1	0.2	GO:0036511	trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1	0.2	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.2	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.2	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1	0.5	GO:0035810	positive regulation of urine volume(GO:0035810)
0.1	1.0	GO:0036258	multivesicular body assembly(GO:0036258)
0.1	0.5	GO:0045475	locomotor rhythm(GO:0045475)
0.1	0.3	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.9	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.2	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.2	GO:0048820	hair follicle maturation(GO:0048820)
0.1	0.7	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.1	0.3	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.2	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.1	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.1	1.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.3	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.1	0.7	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.2	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.1	0.1	GO:2001138	regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.1	0.3	GO:0035739	CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
0.1	0.1	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.1	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1	0.1	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1	1.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.2	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.1	4.2	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1	0.7	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.1	0.1	GO:1904292	regulation of ERAD pathway(GO:1904292) positive regulation of ERAD pathway(GO:1904294)
0.1	0.2	GO:0006405	RNA export from nucleus(GO:0006405)
0.1	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.1	0.2	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1	0.4	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.2	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.1	0.1	GO:0044209	AMP salvage(GO:0044209)
0.1	0.1	GO:0045348	positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1	0.3	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.2	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.1	GO:0060467	negative regulation of fertilization(GO:0060467)
0.1	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.4	GO:0034982	mitochondrial protein processing(GO:0034982)
0.1	0.1	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1	0.1	GO:0071362	cellular response to ether(GO:0071362)
0.1	0.1	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.1	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.1	0.2	GO:0036100	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1	0.8	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1	1.0	GO:0007141	male meiosis I(GO:0007141)
0.1	0.1	GO:0097264	self proteolysis(GO:0097264)
0.1	0.4	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.1	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.1	0.1	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	0.2	GO:0014904	myotube cell development(GO:0014904)
0.1	0.3	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.1	0.6	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.1	4.7	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.1	1.0	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1	0.1	GO:2000479	regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.1	0.1	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1	0.3	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.3	GO:0046479	glycosphingolipid catabolic process(GO:0046479)
0.0	0.1	GO:0089712	L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0	0.1	GO:0002638	negative regulation of immunoglobulin production(GO:0002638)
0.0	1.1	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.7	GO:0015879	carnitine transport(GO:0015879)
0.0	0.1	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	1.7	GO:0000045	autophagosome assembly(GO:0000045)
0.0	0.3	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.0	0.4	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.1	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	1.2	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.1	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.7	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.2	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.0	GO:0072019	proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0	0.5	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.5	GO:0075713	establishment of integrated proviral latency(GO:0075713)
0.0	0.2	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0	0.1	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0	0.1	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.0	0.3	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0006231	dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.1	GO:0071105	response to interleukin-11(GO:0071105)
0.0	0.2	GO:0051414	response to cortisol(GO:0051414)
0.0	1.0	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.4	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:1902299	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0	0.1	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.5	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.1	GO:0080009	mRNA methylation(GO:0080009)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.0	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	2.0	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.6	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.2	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.1	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.9	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.4	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0	0.1	GO:0051299	mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0	0.4	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.6	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.1	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.1	GO:0060019	radial glial cell differentiation(GO:0060019)
0.0	0.1	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.0	0.3	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.2	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.3	GO:0018126	protein hydroxylation(GO:0018126)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.0	GO:0010868	negative regulation of triglyceride biosynthetic process(GO:0010868)
0.0	0.2	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.2	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	1.1	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0	0.2	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.2	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.1	GO:0050912	detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0	0.0	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.0	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.0	0.1	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.0	3.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.1	GO:0051589	negative regulation of neurotransmitter transport(GO:0051589)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.1	GO:0009651	response to salt stress(GO:0009651)
0.0	0.2	GO:1902415	regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416) regulation of RNA binding(GO:1905214) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0070627	ferrous iron import(GO:0070627)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.0	0.1	GO:0033385	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0	0.2	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.2	GO:0060356	leucine import(GO:0060356)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.9	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.1	GO:1901490	regulation of lymphangiogenesis(GO:1901490)
0.0	0.2	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.2	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0052314	phytoalexin metabolic process(GO:0052314)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:1902669	positive regulation of axon guidance(GO:1902669)
0.0	0.2	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.5	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	1.3	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.3	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0	0.1	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.5	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.2	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.2	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.2	GO:0006554	lysine catabolic process(GO:0006554)
0.0	0.8	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	1.6	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0044062	regulation of excretion(GO:0044062)
0.0	0.3	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.0	0.3	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0043366	beta selection(GO:0043366)
0.0	0.1	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	1.8	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.0	GO:0006014	D-ribose metabolic process(GO:0006014)
0.0	0.0	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.0	0.0	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.1	GO:0006711	estrogen catabolic process(GO:0006711)
0.0	0.5	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.3	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.8	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.3	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.3	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0	0.4	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0	0.1	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400) oxidative stress-induced premature senescence(GO:0090403)
0.0	0.2	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.2	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0072221	distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0	0.2	GO:0045903	positive regulation of translational fidelity(GO:0045903)
0.0	0.1	GO:0003285	septum secundum development(GO:0003285)
0.0	0.1	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	0.1	GO:0090314	positive regulation of protein targeting to membrane(GO:0090314)
0.0	0.1	GO:0042634	regulation of hair cycle(GO:0042634)
0.0	0.3	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0061107	seminal vesicle development(GO:0061107)
0.0	0.2	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.0	0.0	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0	0.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.2	GO:0006983	ER overload response(GO:0006983)
0.0	0.5	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:0033133	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0019046	release from viral latency(GO:0019046)
0.0	0.1	GO:0009624	response to nematode(GO:0009624)
0.0	0.2	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.2	GO:0010869	regulation of receptor biosynthetic process(GO:0010869)
0.0	0.1	GO:0009311	oligosaccharide metabolic process(GO:0009311)
0.0	0.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.0	0.1	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0	0.0	GO:2000209	regulation of anoikis(GO:2000209)
0.0	0.0	GO:0051446	positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.1	GO:0051231	spindle elongation(GO:0051231)
0.0	0.3	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.3	GO:0006900	membrane budding(GO:0006900)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.3	GO:0019184	glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0007320	insemination(GO:0007320)
0.0	0.1	GO:1904251	regulation of bile acid metabolic process(GO:1904251)
0.0	0.2	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.2	GO:0009082	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0	0.2	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.7	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0	0.0	GO:0061074	regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0	0.1	GO:0048636	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	0.5	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.2	GO:0090189	regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0	0.1	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
0.0	0.2	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0021604	cranial nerve structural organization(GO:0021604)
0.0	0.3	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.1	GO:0051594	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0044179	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0	0.1	GO:1990637	response to prolactin(GO:1990637)
0.0	0.3	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.4	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.0	GO:2000197	regulation of ribonucleoprotein complex localization(GO:2000197)
0.0	0.0	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.3	GO:1904705	regulation of vascular smooth muscle cell proliferation(GO:1904705) vascular smooth muscle cell proliferation(GO:1990874)
0.0	0.0	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.5	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.3	GO:2001222	regulation of neuron migration(GO:2001222)
0.0	0.2	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.4	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.0	GO:0009266	response to temperature stimulus(GO:0009266)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0006529	asparagine biosynthetic process(GO:0006529)
0.0	0.1	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.3	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.1	GO:0030450	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0	0.0	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.0	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.0	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.1	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.0	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0051882	mitochondrial depolarization(GO:0051882)
0.0	0.1	GO:0001712	ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0	0.0	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035358) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.1	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.1	GO:0048793	pronephros development(GO:0048793)
0.0	0.4	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:0021681	cerebellar granular layer development(GO:0021681)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0034333	adherens junction assembly(GO:0034333)
0.0	0.2	GO:0030539	male genitalia development(GO:0030539)
0.0	0.1	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0	0.2	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.0	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.2	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.1	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.8	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0046778	modification by virus of host mRNA processing(GO:0046778)
0.0	0.4	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.1	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	0.5	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.0	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.0	0.0	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.1	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.3	GO:0032465	regulation of cytokinesis(GO:0032465)
0.0	0.1	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.6	GO:0007588	excretion(GO:0007588)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.5	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.2	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.0	0.0	GO:0090169	regulation of spindle assembly(GO:0090169)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0032026	response to magnesium ion(GO:0032026)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.0	0.0	GO:0015855	pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0	0.2	GO:0033139	regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139) positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.1	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.0	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:1903214	regulation of protein targeting to mitochondrion(GO:1903214)
0.0	0.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.1	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.0	0.0	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.1	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.0	0.0	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.0	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0090024	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0	0.1	GO:0050684	regulation of mRNA processing(GO:0050684)
0.0	0.0	GO:0019732	antifungal humoral response(GO:0019732)
0.0	0.0	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.2	GO:0008542	visual learning(GO:0008542)
0.0	0.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.0	GO:0060430	lung saccule development(GO:0060430)
0.0	0.1	GO:0044774	mitotic DNA integrity checkpoint(GO:0044774)
0.0	0.0	GO:1901859	negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.0	GO:0044211	CTP salvage(GO:0044211)
0.0	0.0	GO:0002818	intracellular defense response(GO:0002818)
0.0	0.1	GO:0014029	neural crest formation(GO:0014029)
0.0	0.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.0	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0051492	regulation of stress fiber assembly(GO:0051492)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707) strand invasion(GO:0042148)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.8	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0015697	quaternary ammonium group transport(GO:0015697)
0.0	0.0	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.0	GO:0072553	terminal button organization(GO:0072553)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.1	GO:0071806	protein transmembrane transport(GO:0071806)
0.0	0.0	GO:0021539	subthalamus development(GO:0021539)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.0	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.0	GO:0045408	regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	1.3	GO:0007517	muscle organ development(GO:0007517)
0.0	0.0	GO:0072717	cellular response to actinomycin D(GO:0072717)
0.0	0.0	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0030214	hyaluronan catabolic process(GO:0030214)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.1	GO:0007098	centrosome cycle(GO:0007098)
0.0	0.0	GO:0032204	regulation of telomere maintenance(GO:0032204)
0.0	0.0	GO:2000811	negative regulation of anoikis(GO:2000811)
0.0	0.0	GO:0060966	regulation of posttranscriptional gene silencing(GO:0060147) regulation of gene silencing by miRNA(GO:0060964) regulation of gene silencing by RNA(GO:0060966) regulation of gene silencing(GO:0060968)
0.0	0.1	GO:0097106	postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) excitatory synapse assembly(GO:1904861)
0.0	0.0	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.0	0.1	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.1	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.0	GO:0051445	regulation of meiotic cell cycle(GO:0051445)
0.0	0.0	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.0	GO:0019062	virion attachment to host cell(GO:0019062)
0.0	0.1	GO:0044321	response to leptin(GO:0044321)
0.0	0.1	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.0	0.1	GO:0039703	viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.4	6.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4	7.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.4	1.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.4	8.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.4	5.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3	19.6	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3	19.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	4.6	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.3	1.7	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.3	5.0	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.3	2.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3	2.6	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.3	18.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2	5.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.2	2.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	0.5	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.2	6.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2	3.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	3.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	4.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	3.9	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.2	3.5	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.2	1.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2	1.4	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	2.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	3.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.9	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	3.8	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.1	4.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	3.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	3.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	15.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.7	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	2.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	7.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	3.8	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	2.9	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	8.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	1.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	1.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.4	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1	1.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	1.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.9	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.1	2.4	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.1	1.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	4.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	0.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	1.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	4.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	1.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	1.0	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	2.2	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	6.7	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.1	1.0	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	9.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	0.8	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	0.5	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.8	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	1.7	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	1.0	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	2.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.0	0.5	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	1.1	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	1.0	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	3.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	6.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.3	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	1.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	1.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	1.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.7	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	1.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	Genes involved in Signaling by TGF-beta Receptor Complex
0.0	0.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.3	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.3	REACTOME DEADENYLATION DEPENDENT MRNA DECAY	Genes involved in Deadenylation-dependent mRNA decay
0.0	0.3	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.6	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	3.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	2.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	2.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	7.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	3.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	2.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.1	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	27.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
1.2	19.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
1.2	6.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.9	20.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8	6.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.8	16.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.6	5.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5	5.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.4	5.7	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.4	0.4	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.4	3.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4	3.3	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.4	5.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.4	0.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.3	5.6	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3	5.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.3	9.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.3	5.9	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.3	5.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.3	0.6	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.3	1.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3	5.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3	5.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	8.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.3	3.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	6.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.3	4.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.3	13.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	0.3	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.3	16.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	2.3	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.3	5.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.3	4.8	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.3	0.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.2	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.2	7.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2	5.8	REACTOME KINESINS	Genes involved in Kinesins
0.2	4.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	0.6	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.2	18.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	2.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	5.8	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	2.0	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	3.4	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2	6.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	1.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.2	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	3.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	0.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.2	10.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	4.8	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	3.9	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.2	0.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	6.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2	1.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.2	1.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.2	5.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	2.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	6.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	9.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	3.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	3.0	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	3.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	0.2	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1	1.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	10.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	2.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	2.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	0.7	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	2.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	1.9	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	2.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	1.0	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	1.9	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	1.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	0.7	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	0.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	2.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	2.1	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.1	2.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	3.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	2.3	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.1	1.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	9.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	6.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	0.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	1.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.0	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	2.9	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	13.2	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.1	2.5	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
0.1	1.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	4.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	1.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	4.6	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	4.3	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	6.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	0.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	1.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	3.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	2.5	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.1	3.7	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1	1.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	0.3	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.1	1.6	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1	1.4	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	3.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	0.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	2.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	0.3	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	0.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	12.6	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	0.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	6.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1	0.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	0.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	1.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	0.3	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	0.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	0.6	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	1.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	7.7	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	6.2	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.8	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.9	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	1.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.4	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	1.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	2.1	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.3	REACTOME SEMAPHORIN INTERACTIONS	Genes involved in Semaphorin interactions
0.0	0.6	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	1.4	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME SIGNALLING TO RAS	Genes involved in Signalling to RAS
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.7	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	1.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.9	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	3.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	3.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	2.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	3.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.6	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.7	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.8	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.7	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	1.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	35.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	4.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.9	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	1.5	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	1.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	1.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	1.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	1.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	3.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	2.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.1	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.7	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.6	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	3.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	2.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.8	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.0	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	3.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.3	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.1	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	4.4	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.6	2.3	GO:0001512	dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.3	2.1	GO:0047086	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.3	1.0	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.2	1.4	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	0.6	GO:0004766	spermidine synthase activity(GO:0004766)
0.2	0.5	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2	0.8	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.2	0.6	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	1.7	GO:0005243	gap junction channel activity(GO:0005243)
0.1	1.2	GO:0089720	caspase binding(GO:0089720)
0.1	1.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.4	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.2	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1	0.6	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	1.4	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.2	GO:0004040	amidase activity(GO:0004040) fucose binding(GO:0042806)
0.1	0.7	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.7	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.1	0.6	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.3	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.4	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.7	GO:0045499	chemorepellent activity(GO:0045499)
0.0	1.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0	0.3	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.4	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.5	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.4	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.5	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	1.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	1.1	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.1	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.0	0.5	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.9	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	1.0	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0	0.2	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.2	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.5	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.0	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.3	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	29.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.5	1.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.4	9.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	0.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.4	4.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.3	18.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	9.6	PID ATM PATHWAY	ATM pathway
0.2	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.2	5.6	PID IL5 PATHWAY	IL5-mediated signaling events
0.2	2.1	PID MYC PATHWAY	C-MYC pathway
0.2	13.8	PID AURORA B PATHWAY	Aurora B signaling
0.2	12.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2	15.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.2	6.2	PID ATR PATHWAY	ATR signaling pathway
0.2	5.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.2	9.1	PID PLK1 PATHWAY	PLK1 signaling events
0.2	2.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	1.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	4.5	PID AURORA A PATHWAY	Aurora A signaling
0.1	2.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	5.9	PID IFNG PATHWAY	IFN-gamma pathway
0.1	1.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	1.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	3.7	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	4.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	9.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	9.0	PID LKB1 PATHWAY	LKB1 signaling events
0.1	4.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.1	1.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.1	0.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	2.0	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	4.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	7.4	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	11.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	1.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	1.7	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	0.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	1.0	PID SHP2 PATHWAY	SHP2 signaling
0.1	0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	3.5	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	4.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	2.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	3.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	1.2	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.1	1.5	PID BARD1 PATHWAY	BARD1 signaling events
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.3	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	2.0	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	5.0	PID E2F PATHWAY	E2F transcription factor network
0.1	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	4.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	0.5	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	1.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	2.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	0.6	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.5	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.4	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	1.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	1.0	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	1.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.9	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID FOXO PATHWAY	FoxO family signaling
0.0	0.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.8	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	4.6	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	2.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	1.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	1.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	1.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.8	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	3.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	2.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.9	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	1.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.6	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.2	2.2	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.2	0.8	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2	2.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	4.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	1.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	3.7	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.8	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	0.7	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	2.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	3.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.1	0.8	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	2.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	5.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	3.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	3.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	2.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	1.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.7	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	2.9	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	9.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.6	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	1.9	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	1.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	5.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	2.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	2.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.9	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.1	2.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	1.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	3.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	1.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	1.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.9	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	1.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.9	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.5	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.5	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.5	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	5.4	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	1.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	3.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	2.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.8	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	2.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.6	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.6	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	5.5	REACTOME TRANSLATION	Genes involved in Translation
0.0	2.2	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.8	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	1.1	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.6	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	2.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.1	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.2	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.6	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.3	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2	3.9	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	4.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	8.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.8	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	1.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	2.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	1.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	1.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	0.5	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	3.1	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	0.9	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	6.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.9	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	1.2	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.1	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.7	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.5	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	10.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	0.2	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	0.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	2.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.0	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	1.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	1.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	2.0	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.6	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.7	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	1.0	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	9.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	5.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.6	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.0	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	1.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.3	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.2	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.0	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.3	GO:0005916	fascia adherens(GO:0005916)
0.3	1.3	GO:0042643	actomyosin, actin portion(GO:0042643)
0.2	0.8	GO:0070695	FHF complex(GO:0070695)
0.2	1.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.2	1.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	5.9	GO:1904115	axon cytoplasm(GO:1904115)
0.1	2.7	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	3.2	GO:0005921	gap junction(GO:0005921)
0.1	0.2	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.4	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.6	GO:0001533	cornified envelope(GO:0001533)
0.1	0.8	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.1	1.2	GO:0005861	troponin complex(GO:0005861)
0.1	0.8	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.0	2.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	2.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	1.0	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	1.9	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.8	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0035976	AP1 complex(GO:0035976)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	7.8	GO:0005815	microtubule organizing center(GO:0005815)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID RAS PATHWAY	Regulation of Ras family activation
0.1	1.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.3	NABA COLLAGENS	Genes encoding collagen proteins
0.0	1.8	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.4	1.6	GO:0031716	calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.2	1.0	GO:0047023	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.2	1.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.2	1.0	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2	12.0	GO:0005044	scavenger receptor activity(GO:0005044)
0.2	0.7	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.2	0.5	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.4	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	4.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	1.5	GO:0031013	troponin I binding(GO:0031013)
0.1	1.3	GO:0031433	telethonin binding(GO:0031433)
0.1	0.6	GO:0070728	leucine binding(GO:0070728)
0.1	0.6	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	1.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	1.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	1.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	1.6	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	1.0	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.8	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	2.5	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	1.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.5	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	1.4	GO:0005521	lamin binding(GO:0005521)
0.0	4.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.5	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.3	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	2.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	1.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.9	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.8	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.4	GO:0045159	myosin II binding(GO:0045159)
0.0	0.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	2.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.6	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0042169	SH2 domain binding(GO:0042169)
0.0	1.0	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.3	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.3	GO:0070330	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330)
0.0	1.1	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4	2.9	GO:0001849	complement component C1q binding(GO:0001849)
0.3	0.8	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.2	1.0	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.9	GO:0031433	telethonin binding(GO:0031433)
0.1	0.4	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.1	0.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.8	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	1.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	3.1	GO:0016504	peptidase activator activity(GO:0016504)
0.0	0.2	GO:0047708	biotinidase activity(GO:0047708)
0.0	1.0	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.6	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.2	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.4	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.6	GO:0004601	peroxidase activity(GO:0004601)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.2	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	1.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	1.0	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.8	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.4	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	2.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.5	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.1	0.8	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.1	GO:0030689	Noc complex(GO:0030689)
0.0	0.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.5	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0043194	axon initial segment(GO:0043194)
0.0	0.2	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.2	GO:0000974	Prp19 complex(GO:0000974)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.4	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.6	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	7.7	GO:0032395	MHC class II receptor activity(GO:0032395)
0.4	1.2	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.4	1.1	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4	1.8	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.3	1.6	GO:0004905	type I interferon receptor activity(GO:0004905)
0.3	0.8	GO:0050135	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.3	2.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.3	1.9	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3	1.8	GO:0008142	oxysterol binding(GO:0008142)
0.2	1.1	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.2	0.7	GO:0005148	prolactin receptor binding(GO:0005148)
0.2	1.2	GO:0046979	TAP2 binding(GO:0046979)
0.2	0.6	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.2	0.5	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.2	1.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	0.7	GO:0035651	AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2	0.5	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.2	0.5	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.4	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	1.3	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.4	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.5	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1	0.8	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.1	0.5	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	0.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.7	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	2.1	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1	0.5	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	1.4	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	1.5	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	1.7	GO:0070330	aromatase activity(GO:0070330)
0.1	1.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.3	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1	0.2	GO:0051765	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1	0.5	GO:0071253	connexin binding(GO:0071253)
0.1	0.3	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.3	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1	0.7	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.4	GO:1990254	keratin filament binding(GO:1990254)
0.1	0.6	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	0.5	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	1.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.4	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.8	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.1	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1	0.2	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1	2.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.5	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.2	GO:1904493	Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1	0.3	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.1	0.4	GO:0032393	MHC class I receptor activity(GO:0032393)
0.1	0.2	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.9	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.2	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.0	0.8	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	1.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.9	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	1.1	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.2	GO:0035473	lipase binding(GO:0035473)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.6	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0	0.3	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.8	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0090556	apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0	0.4	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0032145	4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	5.4	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	1.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.4	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0032551	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.2	GO:0004447	iodide peroxidase activity(GO:0004447)
0.0	0.3	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.1	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	1.5	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.4	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.2	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.4	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.1	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	1.2	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.7	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.2	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.3	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:1904599	advanced glycation end-product binding(GO:1904599)
0.0	0.6	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.4	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.1	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.0	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.6	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.0	GO:0035276	ethanol binding(GO:0035276)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.1	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	1.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0046997	sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.1	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	1.8	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	1.3	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	3.9	GO:0003924	GTPase activity(GO:0003924)
0.0	0.5	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.1	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.0	0.7	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0001047	core promoter binding(GO:0001047)
0.0	0.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	6.5	GO:0052828	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.9	3.7	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.7	3.4	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.6	2.3	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.4	1.9	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.4	7.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.4	2.1	GO:1903135	cupric ion binding(GO:1903135)
0.3	7.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	0.7	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.2	0.7	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.2	3.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	1.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.2	1.0	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2	1.0	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2	3.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.2	18.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	2.2	GO:0038132	neuregulin binding(GO:0038132)
0.2	0.5	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.1	1.6	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	1.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	0.4	GO:0016672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1	0.7	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1	1.8	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.5	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.4	GO:0008859	exoribonuclease II activity(GO:0008859)
0.1	1.7	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.6	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1	0.6	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	2.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	1.0	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	1.0	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	2.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.6	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1	0.3	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1	0.7	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	0.4	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.6	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1	0.5	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	2.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	2.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.5	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	1.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.6	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	0.5	GO:1990254	keratin filament binding(GO:1990254)
0.1	0.2	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	2.7	GO:0001848	complement binding(GO:0001848)
0.1	0.6	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	1.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	1.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	2.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	0.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.5	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.1	0.4	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.2	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1	0.2	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	1.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.4	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1	0.6	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.4	GO:0019863	IgE binding(GO:0019863)
0.1	0.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.2	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.0	0.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.1	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.2	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0	1.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	1.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0	0.1	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	0.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	2.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0004882	androgen receptor activity(GO:0004882)
0.0	0.3	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.3	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.0	6.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.3	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.4	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.2	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	1.8	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.9	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.4	GO:0003696	satellite DNA binding(GO:0003696)
0.0	1.1	GO:0005548	phospholipid transporter activity(GO:0005548)
0.0	0.5	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	24.5	GO:0005198	structural molecule activity(GO:0005198)
0.0	1.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	1.5	GO:0050699	WW domain binding(GO:0050699)
0.0	0.5	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.3	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.2	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.3	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	3.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0	0.3	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.2	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.7	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.0	0.5	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.2	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.5	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	3.2	GO:0044325	ion channel binding(GO:0044325)
0.0	0.1	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.0	1.0	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	1.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0019158	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.5	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.5	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0001847	opsonin receptor activity(GO:0001847) peptidoglycan receptor activity(GO:0016019)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0	0.2	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.8	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.0	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0	0.1	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0	0.2	GO:0031402	sodium ion binding(GO:0031402)
0.0	0.8	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.0	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0	0.1	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0	0.0	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.0	2.0	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.0	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.3	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.0	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.0	0.6	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	1.4	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.4	GO:0042287	MHC protein binding(GO:0042287)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	1.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
1.0	49.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.9	24.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.8	5.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.8	20.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.7	14.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.7	13.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.7	7.8	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.7	11.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.7	2.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.6	14.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.6	10.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.6	5.9	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.6	37.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.6	10.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.5	12.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.5	5.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5	4.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	13.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.5	8.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.5	4.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.5	13.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4	8.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4	0.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.4	2.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.4	12.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	5.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.4	6.9	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.4	4.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.4	7.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.3	6.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	13.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.3	6.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3	21.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	10.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3	5.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.3	8.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.2	6.8	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	10.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	0.4	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.2	3.8	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.2	6.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	2.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.2	24.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.2	1.2	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.2	6.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.2	4.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	4.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	10.8	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.2	4.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	3.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	1.9	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	1.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2	3.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	8.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	12.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	1.8	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	7.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	2.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	6.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	0.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	2.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.8	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	3.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	5.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	8.0	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.1	0.6	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	3.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	1.2	REACTOME OPSINS	Genes involved in Opsins
0.1	1.7	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	3.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	2.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	1.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	1.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.5	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.5	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.1	1.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	1.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	2.9	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	3.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	1.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	1.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	9.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	0.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	1.3	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.1	5.4	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.1	3.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	1.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	5.1	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	0.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	1.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	1.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	0.4	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	1.7	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	3.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.5	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	1.0	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	1.4	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	2.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.2	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.3	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.0	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.4	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	2.7	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	12.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	3.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	6.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.0	REACTOME OPSINS	Genes involved in Opsins
0.1	2.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.9	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	1.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.6	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.0	1.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.6	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	2.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	2.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	2.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.7	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	1.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.6	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	1.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	13.8	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8	12.7	GO:0097512	cardiac myofibril(GO:0097512)
0.7	3.6	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.7	9.7	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6	3.6	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.5	3.7	GO:0032584	growth cone membrane(GO:0032584)
0.5	10.5	GO:0005861	troponin complex(GO:0005861)
0.5	3.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.5	4.5	GO:0071953	elastic fiber(GO:0071953)
0.4	1.3	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.3	1.0	GO:0043291	RAVE complex(GO:0043291)
0.3	1.6	GO:0042643	actomyosin, actin portion(GO:0042643)
0.3	0.9	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.3	1.7	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.3	0.5	GO:0097454	Schwann cell microvillus(GO:0097454)
0.2	2.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2	0.2	GO:0005955	calcineurin complex(GO:0005955)
0.2	3.3	GO:0008091	spectrin(GO:0008091)
0.2	8.3	GO:0005859	muscle myosin complex(GO:0005859)
0.2	0.2	GO:0019034	viral replication complex(GO:0019034)
0.2	3.4	GO:0000124	SAGA complex(GO:0000124)
0.2	1.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	1.6	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.2	0.9	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	0.7	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2	0.7	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	1.7	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2	0.9	GO:0031673	H zone(GO:0031673)
0.2	4.6	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	2.6	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.2	1.0	GO:0000125	PCAF complex(GO:0000125)
0.2	1.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	0.8	GO:0044611	nuclear pore inner ring(GO:0044611)
0.2	0.4	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2	0.5	GO:0070195	growth hormone receptor complex(GO:0070195)
0.2	15.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.2	0.7	GO:0030891	VCB complex(GO:0030891)
0.2	1.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.2	0.2	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.2	0.7	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.2	0.5	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	0.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	2.9	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.4	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.1	0.1	GO:0043292	contractile fiber(GO:0043292)
0.1	0.6	GO:0000798	nuclear cohesin complex(GO:0000798)
0.1	1.4	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	2.8	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.6	GO:0032301	MutSalpha complex(GO:0032301)
0.1	1.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.7	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	1.0	GO:0034704	calcium channel complex(GO:0034704)
0.1	0.4	GO:0031523	Myb complex(GO:0031523)
0.1	1.9	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	1.2	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.1	2.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.8	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.1	GO:0097422	tubular endosome(GO:0097422)
0.1	1.0	GO:0014802	terminal cisterna(GO:0014802)
0.1	0.6	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	1.4	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	0.6	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.1	1.4	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	2.8	GO:0071564	npBAF complex(GO:0071564)
0.1	0.5	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.1	0.8	GO:0071203	WASH complex(GO:0071203)
0.1	1.0	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	0.3	GO:0072563	endothelial microparticle(GO:0072563)
0.1	3.1	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	0.5	GO:0044308	axonal spine(GO:0044308)
0.1	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.3	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.3	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	0.4	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.1	0.4	GO:0051286	cell tip(GO:0051286)
0.1	0.3	GO:0031213	RSF complex(GO:0031213)
0.1	0.2	GO:0032806	carboxy-terminal domain protein kinase complex(GO:0032806)
0.1	0.5	GO:0001739	sex chromatin(GO:0001739)
0.1	3.5	GO:0097346	INO80-type complex(GO:0097346)
0.1	0.3	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.1	0.7	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.1	0.9	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.9	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	0.8	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.3	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1	0.6	GO:0001520	outer dense fiber(GO:0001520)
0.1	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1	2.5	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	0.7	GO:1990111	spermatoproteasome complex(GO:1990111)
0.1	0.1	GO:0005915	zonula adherens(GO:0005915)
0.1	0.3	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.1	0.3	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1	0.7	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1	0.9	GO:0097486	multivesicular body lumen(GO:0097486)
0.1	0.3	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	2.4	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.6	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.1	2.3	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.2	GO:1990015	mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1	2.0	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	0.6	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.1	0.6	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.6	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.9	GO:0005833	hemoglobin complex(GO:0005833)
0.1	1.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.5	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.5	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1	1.7	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.5	GO:0031415	NatA complex(GO:0031415)
0.1	0.3	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	0.5	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.5	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.4	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
0.1	0.4	GO:0097165	nuclear stress granule(GO:0097165)
0.1	0.4	GO:1990909	Wnt signalosome(GO:1990909)
0.1	0.4	GO:0001652	granular component(GO:0001652)
0.1	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	1.5	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	0.3	GO:0055087	Ski complex(GO:0055087)
0.1	1.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.2	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	0.4	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.2	GO:0060187	cell pole(GO:0060187)
0.1	0.1	GO:0098839	postsynaptic density membrane(GO:0098839)
0.1	3.5	GO:0045171	intercellular bridge(GO:0045171)
0.1	0.8	GO:0031595	nuclear proteasome complex(GO:0031595)
0.1	0.3	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	0.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.1	0.5	GO:0097227	sperm annulus(GO:0097227)
0.1	1.3	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.2	GO:0031372	UBC13-MMS2 complex(GO:0031372)
0.1	1.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.2	GO:0097441	basilar dendrite(GO:0097441)
0.1	0.4	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.3	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1	0.2	GO:0044305	calyx of Held(GO:0044305)
0.1	2.3	GO:0000421	autophagosome membrane(GO:0000421)
0.1	0.2	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.1	0.4	GO:0034464	BBSome(GO:0034464)
0.1	0.4	GO:0016272	prefoldin complex(GO:0016272)
0.1	1.1	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	1.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1	0.4	GO:0032982	myosin filament(GO:0032982)
0.1	1.6	GO:0031430	M band(GO:0031430)
0.1	1.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:1990423	RZZ complex(GO:1990423)
0.1	0.8	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.2	GO:0001940	male pronucleus(GO:0001940)
0.1	0.5	GO:0031105	septin complex(GO:0031105)
0.1	1.0	GO:0005884	actin filament(GO:0005884)
0.1	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	1.2	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.1	0.5	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	0.5	GO:0042382	paraspeckles(GO:0042382)
0.1	0.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.1	0.7	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	0.7	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.8	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	1.2	GO:0043218	compact myelin(GO:0043218)
0.1	1.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.8	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.4	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.3	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1	6.4	GO:0016605	PML body(GO:0016605)
0.1	0.7	GO:0031209	SCAR complex(GO:0031209)
0.1	21.1	GO:0005667	transcription factor complex(GO:0005667)
0.1	0.4	GO:0033643	host cell part(GO:0033643)
0.1	0.2	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.1	0.5	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.1	0.6	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	1.6	GO:0015030	Cajal body(GO:0015030)
0.0	1.0	GO:0000145	exocyst(GO:0000145)
0.0	0.4	GO:0000322	storage vacuole(GO:0000322)
0.0	0.5	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	1.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.1	GO:0016234	inclusion body(GO:0016234)
0.0	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.3	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0033503	HULC complex(GO:0033503)
0.0	0.1	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.0	0.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.3	GO:0031298	replication fork protection complex(GO:0031298)
0.0	3.7	GO:0042641	actomyosin(GO:0042641)
0.0	0.2	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	1.1	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.0	0.2	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.7	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.5	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.3	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.8	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.2	GO:0071565	nBAF complex(GO:0071565)
0.0	0.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.0	0.2	GO:0032044	DSIF complex(GO:0032044)
0.0	2.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.9	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.7	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.5	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.3	GO:0016011	dystroglycan complex(GO:0016011)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.0	GO:0032302	MutSbeta complex(GO:0032302)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.3	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.3	GO:0005638	lamin filament(GO:0005638)
0.0	0.9	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0097440	apical dendrite(GO:0097440)
0.0	0.2	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	13.1	GO:0016607	nuclear speck(GO:0016607)
0.0	0.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.2	GO:0097255	R2TP complex(GO:0097255)
0.0	0.4	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.3	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.2	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.0	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279)
0.0	0.2	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	0.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.0	GO:0098573	intrinsic component of mitochondrial membrane(GO:0098573)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.7	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.4	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.9	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.3	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.4	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.4	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0036021	endolysosome lumen(GO:0036021)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.1	GO:0005846	nuclear cap binding complex(GO:0005846)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.2	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0005818	astral microtubule(GO:0000235) aster(GO:0005818)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.0	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	2.4	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.7	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0070470	plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.0	1.3	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.3	GO:0097433	dense body(GO:0097433)
0.0	0.0	GO:0060171	stereocilium membrane(GO:0060171)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.5	GO:0043596	nuclear replication fork(GO:0043596)
0.0	1.1	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.6	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.0	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.8	GO:0030133	transport vesicle(GO:0030133)
0.0	1.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.2	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.0	GO:0000243	commitment complex(GO:0000243)
0.0	0.1	GO:0044455	mitochondrial membrane part(GO:0044455)
0.0	2.2	GO:0030496	midbody(GO:0030496)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.2	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.4	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.0	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.0	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0	1.1	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.8	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.0	0.4	GO:0031904	endosome lumen(GO:0031904)
0.0	0.0	GO:1990425	ryanodine receptor complex(GO:1990425)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	1.0	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	1.9	GO:0001650	fibrillar center(GO:0001650)
0.0	0.9	GO:0005746	mitochondrial respiratory chain(GO:0005746)
0.0	0.4	GO:0008305	integrin complex(GO:0008305)
0.0	0.5	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.1	GO:0060091	kinocilium(GO:0060091)
0.0	0.2	GO:0097546	ciliary base(GO:0097546)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.3	GO:0000786	nucleosome(GO:0000786)
0.0	0.0	GO:0097134	cyclin E1-CDK2 complex(GO:0097134)
0.0	0.4	GO:0042629	mast cell granule(GO:0042629)
0.0	0.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.5	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.0	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.0	0.3	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0019815	B cell receptor complex(GO:0019815)
0.0	1.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.2	GO:0034709	methylosome(GO:0034709)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	1.0	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.9	GO:0048475	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0	0.1	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	1.0	GO:0005875	microtubule associated complex(GO:0005875)
0.0	0.7	GO:0005903	brush border(GO:0005903)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.2	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	9.7	GO:0005730	nucleolus(GO:0005730)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	1.8	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	1.4	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.0	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.0	0.7	GO:0005814	centriole(GO:0005814)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.0	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.9	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.4	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	3.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.9	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	2.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	3.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.9	NABA COLLAGENS	Genes encoding collagen proteins
0.0	4.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.4	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	1.1	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.6	PID BMP PATHWAY	BMP receptor signaling
0.0	0.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.9	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.2	6.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	2.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	4.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	4.6	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	3.3	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	12.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3	8.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	10.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	4.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	3.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	2.8	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	3.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	13.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.2	21.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	24.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.1	2.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	2.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	2.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	4.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	1.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	0.3	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.1	3.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	1.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	0.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.9	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.4	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	1.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.7	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.1	0.7	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.6	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1	1.1	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.4	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.1	GO:0072534	perineuronal net(GO:0072534)
0.0	0.4	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.3	GO:0033010	paranodal junction(GO:0033010)
0.0	1.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.4	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
0.5	1.6	GO:0005588	collagen type V trimer(GO:0005588)
0.4	3.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.4	2.3	GO:1990584	cardiac Troponin complex(GO:1990584)
0.3	7.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.3	6.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.3	2.6	GO:1990812	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.3	1.1	GO:0045160	myosin I complex(GO:0045160)
0.3	0.5	GO:0016011	dystroglycan complex(GO:0016011)
0.2	2.8	GO:0097512	cardiac myofibril(GO:0097512)
0.2	4.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	1.1	GO:0070545	PeBoW complex(GO:0070545)
0.2	0.6	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.2	4.4	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2	1.2	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.6	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	2.2	GO:0032433	filopodium tip(GO:0032433)
0.1	0.8	GO:0071203	WASH complex(GO:0071203)
0.1	0.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	0.3	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1	3.5	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.6	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.7	GO:0032982	myosin filament(GO:0032982)
0.1	0.3	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	18.6	GO:0005802	trans-Golgi network(GO:0005802)
0.1	0.5	GO:0042788	polysomal ribosome(GO:0042788)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1	1.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	1.5	GO:0031143	pseudopodium(GO:0031143)
0.1	1.0	GO:0005861	troponin complex(GO:0005861)
0.0	0.6	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	1.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.4	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.3	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	5.0	GO:0031674	I band(GO:0031674)
0.0	1.1	GO:0000922	spindle pole(GO:0000922)
0.0	0.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.3	GO:0005912	adherens junction(GO:0005912)
0.0	0.5	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.5	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0032009	early phagosome(GO:0032009)
0.0	2.1	GO:0005811	lipid particle(GO:0005811)
0.0	1.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.6	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	9.1	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.2	GO:0043234	protein complex(GO:0043234)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.3	GO:1990752	microtubule end(GO:1990752)
0.0	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.3	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0031105	septin complex(GO:0031105)
0.0	1.5	GO:0005901	caveola(GO:0005901)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0042599	lamellar body(GO:0042599)
0.0	0.8	GO:0045178	basal part of cell(GO:0045178)
0.0	1.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.8	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	1.1	GO:0031514	motile cilium(GO:0031514)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.6	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	4.6	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.3	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	2.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.2	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1	0.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.2	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	1.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.6	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	1.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.2	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	3.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	1.1	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.4	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	1.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	0.0	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.4	GO:0016992	lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
1.1	3.4	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
1.0	2.9	GO:0031177	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
1.0	2.9	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.8	2.4	GO:0008859	exoribonuclease II activity(GO:0008859)
0.7	2.0	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.6	2.9	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.6	1.7	GO:0070364	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.5	2.2	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.5	1.6	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5	3.1	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.4	2.5	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.4	6.5	GO:0031996	thioesterase binding(GO:0031996)
0.4	2.4	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.4	2.4	GO:0019238	cyclohydrolase activity(GO:0019238)
0.4	1.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.4	4.3	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.4	3.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.4	5.7	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.4	1.1	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.4	1.4	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.3	1.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.3	1.3	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3	2.0	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3	4.7	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3	0.9	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.3	0.9	GO:0032551	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.3	0.9	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3	4.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.3	3.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.3	2.6	GO:0019237	centromeric DNA binding(GO:0019237)
0.3	1.3	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2	1.5	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2	0.7	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.2	3.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.2	1.8	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2	0.6	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.2	0.4	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.2	1.8	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.2	0.6	GO:0015235	cobalamin transporter activity(GO:0015235)
0.2	0.8	GO:0043515	kinetochore binding(GO:0043515)
0.2	2.8	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	1.0	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.2	1.5	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2	0.8	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2	0.9	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2	1.8	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2	5.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.2	0.7	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2	1.1	GO:0023030	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.2	0.5	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2	4.6	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	0.9	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.2	1.4	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.2	3.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.2	0.6	GO:0004966	galanin receptor activity(GO:0004966)
0.2	0.5	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2	0.5	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.2	0.9	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.2	0.6	GO:0004998	transferrin receptor activity(GO:0004998)
0.2	0.5	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1	0.4	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.1	0.4	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1	1.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	1.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1	0.7	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	1.3	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	0.4	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	1.5	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	2.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	0.9	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1	0.9	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.4	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	1.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.1	0.3	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	1.7	GO:0035173	histone kinase activity(GO:0035173)
0.1	0.4	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	1.0	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	1.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.4	GO:0008410	CoA-transferase activity(GO:0008410)
0.1	3.6	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.1	0.7	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.6	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.1	0.5	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.1	0.7	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.3	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.1	4.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	1.4	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	3.5	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	0.4	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.6	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.1	1.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	6.5	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1	1.7	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.3	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.1	0.2	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	1.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.3	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.3	GO:0015403	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	1.5	GO:0032183	SUMO binding(GO:0032183)
0.1	0.3	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1	0.3	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.1	0.9	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	2.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.5	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	0.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	4.1	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.2	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.2	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	2.0	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.6	GO:0034594	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.1	0.7	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	1.6	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.3	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	0.3	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.1	1.0	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.1	1.2	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.9	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	2.5	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	0.4	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.1	0.5	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1	0.4	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.1	0.2	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.1	0.2	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.1	0.4	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1	0.7	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.2	GO:0004324	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1	1.9	GO:0042165	neurotransmitter binding(GO:0042165)
0.1	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.2	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1	0.4	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.3	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1	0.2	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1	0.2	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.1	0.6	GO:0042834	peptidoglycan binding(GO:0042834)
0.1	0.2	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.1	0.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.2	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1	2.8	GO:0030507	spectrin binding(GO:0030507)
0.1	1.0	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	1.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	3.5	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.7	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.4	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	1.8	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.1	0.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.9	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	1.6	GO:0015248	sterol transporter activity(GO:0015248)
0.1	3.2	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.2	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0	0.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.5	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.8	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.5	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.5	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.9	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.8	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.9	GO:0071837	HMG box domain binding(GO:0071837)
0.0	2.9	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.2	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0	0.2	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.6	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.0	0.3	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.6	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
0.0	1.6	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.3	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0	0.4	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.3	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.2	GO:0097100	supercoiled DNA binding(GO:0097100)
0.0	0.2	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.0	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.9	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	6.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.2	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	1.5	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.2	GO:0001641	group II metabotropic glutamate receptor activity(GO:0001641)
0.0	0.1	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.0	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.3	GO:0050544	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	1.3	GO:0043531	ADP binding(GO:0043531)
0.0	0.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.7	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.6	GO:0048156	tau protein binding(GO:0048156)
0.0	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	1.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	2.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.3	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.2	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0001632	leukotriene B4 receptor activity(GO:0001632)
0.0	0.4	GO:0035198	miRNA binding(GO:0035198)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.7	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.6	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.0	0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.6	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.2	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.0	1.6	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.8	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.9	GO:0030332	cyclin binding(GO:0030332)
0.0	0.8	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.4	GO:0031432	titin binding(GO:0031432)
0.0	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	1.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.7	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.8	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0	0.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.3	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	2.2	GO:0042393	histone binding(GO:0042393)
0.0	1.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.4	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	1.1	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	1.4	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.8	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	2.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0	1.9	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.7	GO:0000049	tRNA binding(GO:0000049)
0.0	0.1	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0	1.1	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.2	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	1.1	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.0	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0	0.3	GO:0010181	FMN binding(GO:0010181)
0.0	0.5	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.0	0.4	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.0	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.2	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	1.1	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.4	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.6	GO:0008200	ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.3	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.9	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0	1.2	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0	1.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	2.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.9	GO:0051117	ATPase binding(GO:0051117)
0.0	0.2	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.5	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.6	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.8	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.0	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0	0.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.3	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.0	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0	0.9	GO:0008144	drug binding(GO:0008144)
0.0	0.2	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.2	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.5	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.0	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.7	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	0.0	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	6.7	GO:0071279	cellular response to cobalt ion(GO:0071279)
1.1	3.4	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.7	4.3	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.7	2.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.6	2.3	GO:1903803	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.6	3.9	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.3	2.5	GO:0006116	NADH oxidation(GO:0006116)
0.3	0.9	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3	0.8	GO:0006106	fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.3	0.8	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.2	0.9	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.2	0.6	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.2	1.1	GO:0009099	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2	0.3	GO:0090427	activation of meiosis(GO:0090427)
0.1	0.4	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.1	0.7	GO:0042816	vitamin B6 metabolic process(GO:0042816)
0.1	1.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	1.6	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	0.4	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	1.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.3	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.3	GO:0015960	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0	0.6	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.3	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	1.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.2	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.0	0.1	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0	2.0	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.2	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.0	0.2	GO:0070943	neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.0	0.7	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.3	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.4	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	1.8	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.3	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.2	GO:0021702	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.1	GO:0045217	cell-cell junction maintenance(GO:0045217) positive regulation of protein localization to centrosome(GO:1904781)
0.0	0.7	GO:0045776	negative regulation of blood pressure(GO:0045776)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.3	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	3.6	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	2.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	2.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	6.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	1.4	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	2.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.9	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	2.0	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.5	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	1.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	2.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.5	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.6	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	1.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	7.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.6	1.7	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.5	1.9	GO:0045179	apical cortex(GO:0045179)
0.3	2.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.3	7.1	GO:0005861	troponin complex(GO:0005861)
0.3	0.9	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.3	3.2	GO:0043203	axon hillock(GO:0043203)
0.3	1.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.3	2.2	GO:0032133	chromosome passenger complex(GO:0032133)
0.3	1.3	GO:0032021	NELF complex(GO:0032021)
0.3	1.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	3.4	GO:0042575	DNA polymerase complex(GO:0042575)
0.2	1.4	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.2	0.7	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.2	1.4	GO:0030061	mitochondrial crista(GO:0030061)
0.2	1.4	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.2	3.2	GO:0042627	chylomicron(GO:0042627)
0.2	0.9	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.2	2.0	GO:0005833	hemoglobin complex(GO:0005833)
0.2	0.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.2	0.6	GO:0000799	nuclear condensin complex(GO:0000799)
0.2	1.7	GO:0005688	U6 snRNP(GO:0005688)
0.2	0.6	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	1.9	GO:0042555	MCM complex(GO:0042555)
0.1	0.7	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	0.5	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	0.6	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	2.1	GO:0045277	respiratory chain complex IV(GO:0045277)
0.1	0.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.8	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.9	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.9	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	0.3	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	1.1	GO:0000124	SAGA complex(GO:0000124)
0.1	3.3	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.4	GO:0055087	Ski complex(GO:0055087)
0.1	0.9	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.1	0.4	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	0.4	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.1	0.9	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	0.5	GO:0034457	Mpp10 complex(GO:0034457)
0.1	0.5	GO:0042825	TAP complex(GO:0042825)
0.1	0.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.9	GO:0097431	mitotic spindle pole(GO:0097431)
0.1	0.8	GO:0061574	ASAP complex(GO:0061574)
0.1	0.3	GO:0000811	GINS complex(GO:0000811)
0.1	3.4	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	1.0	GO:0035859	Seh1-associated complex(GO:0035859)
0.1	0.8	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	1.1	GO:0005687	U4 snRNP(GO:0005687)
0.1	1.0	GO:0000815	ESCRT III complex(GO:0000815)
0.1	0.8	GO:0033391	chromatoid body(GO:0033391)
0.1	1.0	GO:0031209	SCAR complex(GO:0031209)
0.1	0.5	GO:0001520	outer dense fiber(GO:0001520)
0.1	2.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	0.2	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	0.5	GO:0045180	basal cortex(GO:0045180)
0.1	0.3	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.1	0.2	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	4.0	GO:0015030	Cajal body(GO:0015030)
0.1	0.1	GO:0033176	proton-transporting V-type ATPase complex(GO:0033176) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.4	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.1	0.5	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	0.2	GO:1990745	EARP complex(GO:1990745)
0.1	0.6	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.2	GO:0070876	SOSS complex(GO:0070876)
0.1	0.3	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	0.4	GO:0097452	GAIT complex(GO:0097452)
0.0	0.8	GO:0005922	connexon complex(GO:0005922)
0.0	0.8	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.5	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.6	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	3.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.6	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.4	GO:0071439	clathrin complex(GO:0071439)
0.0	0.5	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.3	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.5	GO:0005915	zonula adherens(GO:0005915)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	0.2	GO:1990037	Lewy body core(GO:1990037)
0.0	1.2	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.2	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0031298	replication fork protection complex(GO:0031298)
0.0	1.0	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.7	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	3.8	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.3	GO:0070652	HAUS complex(GO:0070652)
0.0	0.5	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.3	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	1.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	4.6	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.4	GO:0044216	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.3	GO:0032153	cell division site(GO:0032153) cell division site part(GO:0032155)
0.0	0.3	GO:0005767	secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0	0.4	GO:0030686	90S preribosome(GO:0030686)
0.0	0.2	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.5	GO:0097342	ripoptosome(GO:0097342)
0.0	0.4	GO:0017119	Golgi transport complex(GO:0017119)
0.0	1.4	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.9	GO:0016592	mediator complex(GO:0016592)
0.0	0.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.7	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.8	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.1	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.7	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.8	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0045177	apical part of cell(GO:0045177)
0.0	0.2	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.8	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.5	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.5	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	1.3	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.0	GO:0033011	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0	1.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	1.7	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.1	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	2.3	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0061702	inflammasome complex(GO:0061702) NLRP3 inflammasome complex(GO:0072559)
0.0	0.5	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	1.2	GO:0005643	nuclear pore(GO:0005643)
0.0	5.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.3	GO:0005925	cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0	0.7	GO:0098862	brush border(GO:0005903) cluster of actin-based cell projections(GO:0098862)
0.0	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	1.4	GO:0000922	spindle pole(GO:0000922)
0.0	0.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.5	GO:0005871	kinesin complex(GO:0005871)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)
0.0	4.0	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0030681	ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.9	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.0	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.9	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.2	GO:0030117	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.9	GO:0005814	centriole(GO:0005814)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	1.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	3.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	7.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	1.8	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.9	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.5	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.8	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.9	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	3.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	3.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	5.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	5.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	0.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	2.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	1.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.4	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	4.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	1.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.9	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.3	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
1.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
1.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
2.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
5.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
1.0	PID TGFBR PATHWAY	TGF-beta receptor signaling
1.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
1.0	PID AR TF PATHWAY	Regulation of Androgen receptor activity

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	0.4	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.1	0.3	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1	1.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.9	GO:0032190	acrosin binding(GO:0032190)
0.1	2.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	5.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.9	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.8	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.0	0.1	GO:0045174	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	1.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	3.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
1.2	4.9	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
1.2	12.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
1.1	32.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.1	9.7	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
1.1	1.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
1.1	7.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.0	2.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.9	0.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.9	28.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.8	13.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.8	15.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.8	66.4	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.8	0.8	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.7	27.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.7	13.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.6	3.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.6	6.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.6	22.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.6	11.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.6	4.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.6	9.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.6	15.6	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.6	6.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5	16.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5	34.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.5	3.2	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.5	0.5	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.5	7.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.5	2.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.5	23.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.5	10.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.5	2.4	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.4	3.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.4	7.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.4	0.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.4	5.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.4	10.6	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.4	2.6	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.4	7.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4	13.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.4	11.9	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.4	3.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.4	4.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.4	4.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.4	2.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.4	7.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4	13.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.4	1.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.4	10.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.4	8.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.4	7.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	10.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.3	4.8	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.3	6.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	21.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	6.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.3	6.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3	4.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	8.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	1.9	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.3	7.9	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.3	2.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.3	24.6	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.3	12.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.3	1.7	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.3	3.9	REACTOME GLOBAL GENOMIC NER GG NER	Genes involved in Global Genomic NER (GG-NER)
0.3	4.4	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.3	6.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.3	20.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.3	6.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3	11.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	3.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.3	2.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3	1.8	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.3	4.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.2	8.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	6.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.2	1.4	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2	4.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2	5.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.2	4.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.2	3.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.2	2.5	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.2	5.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.2	0.9	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.2	2.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2	5.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	6.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	8.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2	4.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	8.4	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.2	6.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2	4.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	2.5	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.2	2.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	10.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	6.0	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2	2.9	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.2	9.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.2	1.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	2.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	2.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.2	1.2	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.2	4.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2	7.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.2	0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.2	1.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.2	3.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	12.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.1	2.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	4.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1	2.9	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	2.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	0.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	2.0	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	11.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	4.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.7	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	5.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	1.7	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.5	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	2.6	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.1	2.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.5	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	1.7	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.9	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.1	4.2	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	4.5	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	4.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.3	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.1	2.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	6.5	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	5.5	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.1	13.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	6.4	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	3.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	2.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.6	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	0.5	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	2.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	2.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.8	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	5.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	1.5	REACTOME EARLY PHASE OF HIV LIFE CYCLE	Genes involved in Early Phase of HIV Life Cycle
0.1	0.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.5	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	2.1	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	0.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	1.4	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	10.7	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	0.8	REACTOME OPSINS	Genes involved in Opsins
0.1	0.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.1	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	0.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.6	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.1	1.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.2	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	0.5	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	2.9	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	0.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	0.4	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	0.9	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	0.3	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.8	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	1.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	2.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.5	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	4.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.4	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	1.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.8	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	1.2	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.0	1.2	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.4	1.3	GO:1902960	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4	1.2	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.4	1.9	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.4	1.5	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.3	1.8	GO:0098707	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3	0.9	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.3	0.8	GO:0052148	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.2	0.6	GO:2000234	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2	0.6	GO:0016095	polyprenol catabolic process(GO:0016095)
0.2	0.6	GO:0050923	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2	0.9	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.2	0.5	GO:0006597	spermine biosynthetic process(GO:0006597)
0.2	0.7	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2	0.5	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2	2.1	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.2	0.6	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.7	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	0.4	GO:2000412	activation of MAPK activity involved in innate immune response(GO:0035419) positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309) positive regulation of thymocyte migration(GO:2000412)
0.1	1.1	GO:0006116	NADH oxidation(GO:0006116)
0.1	0.8	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.6	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.1	0.5	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	0.4	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	0.5	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	1.1	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.1	0.4	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.1	0.3	GO:0006014	D-ribose metabolic process(GO:0006014)
0.1	1.3	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	1.3	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	1.8	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	1.0	GO:0030450	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1	1.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.8	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.4	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1	0.2	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.5	GO:0046203	spermidine catabolic process(GO:0046203)
0.1	0.8	GO:0030091	protein repair(GO:0030091)
0.1	0.4	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1	0.3	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1	0.3	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.3	GO:1900827	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.4	GO:0034441	plasma lipoprotein particle oxidation(GO:0034441)
0.1	0.2	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1	0.2	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.1	0.4	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.1	1.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.2	GO:0052422	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1	0.2	GO:0043315	positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1	0.4	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	0.3	GO:2000639	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	0.4	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.1	0.2	GO:0006203	dGTP catabolic process(GO:0006203)
0.1	0.5	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.2	GO:0033341	regulation of collagen binding(GO:0033341)
0.1	0.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.3	GO:0021553	olfactory nerve development(GO:0021553)
0.1	0.2	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.2	GO:2000584	regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1	0.6	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	1.1	GO:0006853	carnitine shuttle(GO:0006853)
0.1	0.2	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	0.3	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.5	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.2	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	0.9	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:2000681	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0	0.1	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.0	0.7	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0036090	cleavage furrow ingression(GO:0036090)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.4	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:1903936	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0	0.3	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.2	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	1.9	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.6	GO:0017038	protein import(GO:0017038)
0.0	0.4	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0	0.2	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.2	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.2	GO:0019086	late viral transcription(GO:0019086)
0.0	0.6	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	1.0	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	1.0	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.2	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0	0.2	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.2	GO:0016074	snoRNA metabolic process(GO:0016074)
0.0	1.5	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.0	0.0	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.3	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.2	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	1.3	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.2	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.6	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.2	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.3	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	2.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.3	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	1.2	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.2	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	1.2	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.0	0.1	GO:0072425	signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.0	0.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.1	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.5	GO:0006750	glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.3	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.2	GO:0017062	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.3	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0072233	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0	0.4	GO:0017004	cytochrome complex assembly(GO:0017004)
0.0	0.2	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.2	GO:0070987	error-free translesion synthesis(GO:0070987)
0.0	0.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.1	GO:0097396	response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0	0.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.5	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.0	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	0.3	GO:0051893	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0	0.2	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.1	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0	0.1	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.0	0.1	GO:1901998	toxin transport(GO:1901998)
0.0	0.2	GO:0045008	depyrimidination(GO:0045008)
0.0	0.0	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0	0.2	GO:0035855	megakaryocyte development(GO:0035855)
0.0	1.1	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.2	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.2	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.3	GO:0009452	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	1.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.2	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) L-kynurenine metabolic process(GO:0097052)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	0.2	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.8	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.1	GO:0042373	vitamin K metabolic process(GO:0042373)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	3.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	1.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	3.9	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	3.0	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	1.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	2.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.5	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	1.2	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	2.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.9	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	5.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	5.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	2.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	1.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.6	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.4	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	1.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	5.6	GO:0097209	epidermal lamellar body(GO:0097209)
0.7	4.0	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.5	4.3	GO:0005610	laminin-5 complex(GO:0005610)
0.5	6.1	GO:0097470	ribbon synapse(GO:0097470)
0.4	2.2	GO:0032449	CBM complex(GO:0032449)
0.4	2.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.4	1.8	GO:0031905	early endosome lumen(GO:0031905)
0.4	1.1	GO:0016938	kinesin I complex(GO:0016938)
0.3	1.6	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.3	9.7	GO:0030057	desmosome(GO:0030057)
0.3	2.3	GO:0098845	postsynaptic endosome(GO:0098845)
0.2	1.7	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	1.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	1.1	GO:1990425	ryanodine receptor complex(GO:1990425)
0.2	1.6	GO:0005587	collagen type IV trimer(GO:0005587)
0.2	6.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.2	0.4	GO:0098576	lumenal side of membrane(GO:0098576)
0.2	0.5	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.2	1.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	0.5	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	3.3	GO:0030056	hemidesmosome(GO:0030056)
0.2	2.0	GO:0097433	dense body(GO:0097433)
0.1	0.6	GO:0035838	growing cell tip(GO:0035838)
0.1	0.9	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.4	GO:0044393	microspike(GO:0044393)
0.1	0.5	GO:0045160	myosin I complex(GO:0045160)
0.1	0.5	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1	0.7	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	1.3	GO:0097443	sorting endosome(GO:0097443)
0.1	0.8	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.1	1.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.7	GO:0033269	internode region of axon(GO:0033269)
0.1	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	1.0	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	1.1	GO:0005916	fascia adherens(GO:0005916)
0.1	0.7	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.7	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.1	0.3	GO:0044423	virion(GO:0019012) virion part(GO:0044423)
0.1	0.5	GO:0071986	Ragulator complex(GO:0071986)
0.1	2.8	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	1.3	GO:0090543	Flemming body(GO:0090543)
0.1	2.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	0.7	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.4	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.1	0.7	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	0.8	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.1	0.4	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	2.0	GO:0001533	cornified envelope(GO:0001533)
0.1	0.3	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1	0.1	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.7	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.4	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.1	2.3	GO:0045095	keratin filament(GO:0045095)
0.1	0.3	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	0.5	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	0.3	GO:0005602	complement component C1 complex(GO:0005602)
0.1	0.2	GO:0036398	TCR signalosome(GO:0036398)
0.1	0.4	GO:0033391	chromatoid body(GO:0033391)
0.1	1.0	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	1.5	GO:0032420	stereocilium(GO:0032420)
0.0	0.9	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.6	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.4	GO:0034464	BBSome(GO:0034464)
0.0	1.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.3	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.5	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.0	GO:0002139	stereocilia coupling link(GO:0002139)
0.0	0.3	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0033010	paranodal junction(GO:0033010)
0.0	1.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0045179	apical cortex(GO:0045179)
0.0	0.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0042643	actomyosin, actin portion(GO:0042643)
0.0	0.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.0	0.9	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.3	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.0	0.2	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.4	GO:0031209	SCAR complex(GO:0031209)
0.0	0.3	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	1.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.3	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.0	0.2	GO:0097449	astrocyte projection(GO:0097449)
0.0	3.1	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	2.4	GO:0043195	terminal bouton(GO:0043195)
0.0	0.8	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.3	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.3	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	2.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.0	2.5	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.2	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0032044	DSIF complex(GO:0032044)
0.0	0.9	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.2	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.3	GO:0042588	zymogen granule(GO:0042588)
0.0	0.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.9	GO:0031941	filamentous actin(GO:0031941)
0.0	0.2	GO:0097386	glial cell projection(GO:0097386)
0.0	1.1	GO:0045178	basal part of cell(GO:0045178)
0.0	0.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.5	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.2	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.6	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.3	GO:0030478	actin cap(GO:0030478)
0.0	0.0	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.7	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	2.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0000793	condensed chromosome(GO:0000793)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0097361	CIA complex(GO:0097361)
0.0	0.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	1.1	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.2	GO:0033643	host cell part(GO:0033643)
0.0	0.1	GO:0071159	NF-kappaB complex(GO:0071159)
0.0	0.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0031213	RSF complex(GO:0031213)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	1.2	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.0	GO:0000835	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.7	GO:0043679	axon terminus(GO:0043679)
0.0	0.0	GO:1990075	periciliary membrane compartment(GO:1990075)
0.0	0.8	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0035976	AP1 complex(GO:0035976)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	6.3	GO:0005912	adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0	0.4	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.2	GO:0008021	synaptic vesicle(GO:0008021) exocytic vesicle(GO:0070382)
0.0	0.1	GO:0097125	condensed nuclear chromosome outer kinetochore(GO:0000942) cyclin B1-CDK1 complex(GO:0097125)
0.0	0.0	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.3	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	2.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.4	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.2	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.9	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	3.1	GO:0097319	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.4	1.1	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3	1.1	GO:0035995	detection of muscle stretch(GO:0035995)
0.2	1.1	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of macrophage apoptotic process(GO:2000110)
0.2	0.8	GO:0002317	plasma cell differentiation(GO:0002317)
0.2	0.7	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.2	1.1	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1	0.9	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.4	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	1.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.4	GO:0051685	maintenance of ER location(GO:0051685)
0.1	0.5	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.9	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.3	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1	1.0	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	0.3	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.1	0.2	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.1	0.4	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.8	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.2	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.6	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	1.3	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.1	0.4	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1	0.8	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.7	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.2	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.1	0.2	GO:0051697	protein delipidation(GO:0051697)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	1.8	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.1	0.2	GO:1901656	glycoside transport(GO:1901656)
0.0	0.5	GO:0034465	response to carbon monoxide(GO:0034465)
0.0	0.1	GO:0031660	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0	0.5	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.2	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.3	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.4	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.3	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:1904457	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0	0.1	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0	0.1	GO:0070781	response to biotin(GO:0070781)
0.0	0.3	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.1	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0	0.8	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	2.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.2	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.2	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.1	GO:0036216	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.2	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.1	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.4	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.1	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.3	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.2	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.5	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895)
0.0	0.1	GO:0002884	regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.0	0.1	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115) malonyl-CoA metabolic process(GO:2001293)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.3	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	1.8	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	2.0	GO:0030038	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	1.0	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.2	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	1.0	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.0	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.4	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.7	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.1	GO:0009838	abscission(GO:0009838)
0.0	0.1	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.0	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	1.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.0	0.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	2.1	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.4	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	1.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.0	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.6	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.4	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	5.6	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2	0.9	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
0.2	1.1	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.5	GO:0005471	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	0.4	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	0.9	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.1	1.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.8	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.8	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.9	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	2.5	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.3	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	10.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	4.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	4.6	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	5.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	2.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	4.0	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	2.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	1.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	2.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	4.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	1.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	3.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	1.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	2.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.7	2.0	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.7	2.0	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.4	2.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.4	1.8	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.4	2.5	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3	1.7	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3	2.6	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2	1.2	GO:0034431	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2	1.8	GO:0034235	GPI anchor binding(GO:0034235)
0.2	0.6	GO:0004947	bradykinin receptor activity(GO:0004947)
0.2	1.0	GO:0070097	delta-catenin binding(GO:0070097)
0.2	4.1	GO:0017166	vinculin binding(GO:0017166)
0.2	1.6	GO:0036310	annealing helicase activity(GO:0036310)
0.1	1.8	GO:0038132	neuregulin binding(GO:0038132)
0.1	0.4	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1	1.0	GO:0043426	MRF binding(GO:0043426)
0.1	0.6	GO:0042289	MHC class II protein binding(GO:0042289)
0.1	1.2	GO:0031013	troponin I binding(GO:0031013)
0.1	0.3	GO:0000995	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) transcription factor activity, core RNA polymerase III binding(GO:0000995) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1	1.2	GO:0045159	myosin II binding(GO:0045159)
0.1	1.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	1.5	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.4	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1	1.0	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	1.0	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.3	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.6	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	1.8	GO:0032452	histone demethylase activity(GO:0032452)
0.1	1.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.2	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.5	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	1.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	1.1	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.7	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.9	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	1.6	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.5	GO:0043495	protein anchor(GO:0043495)
0.0	0.7	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.5	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.4	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.5	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	4.1	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.0	0.6	GO:0005123	death receptor binding(GO:0005123)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	1.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	1.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	1.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.7	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	9.8	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.5	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.8	GO:1990254	keratin filament binding(GO:1990254)
0.1	1.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.4	GO:0098625	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1	1.4	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	2.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.6	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	1.0	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.3	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1	0.4	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0	0.8	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	1.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.3	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.4	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	1.6	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0023025	MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0	0.3	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	1.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.5	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.2	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	3.1	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	17.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4	5.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.3	5.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3	7.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	4.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	8.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	4.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	2.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.5	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.1	5.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	1.8	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	1.9	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	0.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	3.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	1.8	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	0.6	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	0.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.0	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	5.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.7	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.9	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.8	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.6	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	2.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.6	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.3	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.5	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.6	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	2.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	1.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.6	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	0.9	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	1.0	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.2	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	1.0	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.6	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	1.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	1.4	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.9	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.0	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.9	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	1.1	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.4	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	0.8	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.0	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.8	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	3.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.8	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	1.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.8	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	1.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	3.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.2	0.5	GO:0070762	nuclear pore transmembrane ring(GO:0070762)
0.1	0.6	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	1.0	GO:0035976	AP1 complex(GO:0035976)
0.1	0.7	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.1	1.7	GO:0005922	connexon complex(GO:0005922)
0.1	0.8	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.5	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1	0.3	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	0.5	GO:0072589	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1	0.3	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.4	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1	0.2	GO:0043159	acrosomal matrix(GO:0043159)
0.1	0.2	GO:0005715	late recombination nodule(GO:0005715)
0.1	0.5	GO:0031415	NatA complex(GO:0031415)
0.1	0.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.4	GO:0071817	MMXD complex(GO:0071817)
0.1	0.6	GO:0033391	chromatoid body(GO:0033391)
0.1	0.7	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.3	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.4	GO:0070552	BRISC complex(GO:0070552)
0.0	0.3	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	1.1	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.3	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.4	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116) sorting endosome(GO:0097443)
0.0	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.5	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	1.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.7	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.5	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.3	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.7	GO:0005815	microtubule organizing center(GO:0005815)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.4	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	0.6	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	1.1	GO:0005901	caveola(GO:0005901)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	1.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	0.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	2.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.6	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	2.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	4.0	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	2.0	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	1.5	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	2.4	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.5	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	1.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	14.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.4	5.8	GO:0019862	IgA binding(GO:0019862)
0.8	4.9	GO:0003796	lysozyme activity(GO:0003796)
0.6	1.8	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.5	2.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4	11.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.3	1.9	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	2.4	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.4	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	2.2	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	1.6	GO:0005243	gap junction channel activity(GO:0005243)
0.1	1.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.3	GO:0080101	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	0.5	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	1.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.8	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	1.4	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.5	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.2	GO:0004040	amidase activity(GO:0004040) fucose binding(GO:0042806)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	1.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	5.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	2.2	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0	0.4	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.7	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.5	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.9	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.7	GO:0032452	histone demethylase activity(GO:0032452)
0.0	1.2	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.8	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.5	GO:0001848	complement binding(GO:0001848)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.4	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0005046	KDEL sequence binding(GO:0005046)
0.0	0.1	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	1.7	GO:0004386	helicase activity(GO:0004386)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	13.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3	1.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	0.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	3.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	0.9	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.2	3.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	3.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	6.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	3.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.2	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	3.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	2.9	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	4.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	5.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.8	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	2.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	0.4	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	0.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.7	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	2.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.7	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	0.8	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.7	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	1.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	2.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	6.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	3.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	2.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	0.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	3.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	0.9	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.1	1.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	1.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	3.7	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.1	1.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.8	REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	Genes involved in E2F mediated regulation of DNA replication
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.1	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	8.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	0.6	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	3.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.3	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.2	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	0.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	3.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	2.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	0.8	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	0.9	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	2.1	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.5	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	5.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.5	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	1.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	1.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	2.8	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.7	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	1.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.5	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.8	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	1.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.1	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.4	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	0.7	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	0.5	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.5	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.5	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	1.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME MITOTIC G1 G1 S PHASES	Genes involved in Mitotic G1-G1/S phases
0.0	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.5	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0071745	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.7	2.0	GO:0097182	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.6	2.3	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.5	1.6	GO:0031262	Ndc80 complex(GO:0031262)
0.5	2.6	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.5	3.8	GO:0097208	alveolar lamellar body(GO:0097208)
0.4	1.3	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.4	1.8	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.3	1.7	GO:0005927	muscle tendon junction(GO:0005927)
0.3	2.3	GO:0005638	lamin filament(GO:0005638)
0.3	4.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.2	0.9	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	0.9	GO:0071001	U4/U6 snRNP(GO:0071001)
0.2	1.7	GO:0032133	chromosome passenger complex(GO:0032133)
0.2	0.9	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2	0.6	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.2	1.1	GO:1990357	terminal web(GO:1990357)
0.2	2.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.2	1.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	0.7	GO:0044611	nuclear pore inner ring(GO:0044611)
0.2	8.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	2.1	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.6	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.3	GO:0098839	postsynaptic density membrane(GO:0098839)
0.1	0.5	GO:0000811	GINS complex(GO:0000811)
0.1	0.8	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	0.9	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	0.9	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.4	GO:0097447	dendritic tree(GO:0097447)
0.1	2.3	GO:0032433	filopodium tip(GO:0032433)
0.1	1.9	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	1.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.1	GO:0005827	polar microtubule(GO:0005827)
0.1	2.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.7	GO:0030061	mitochondrial crista(GO:0030061)
0.1	1.4	GO:0031209	SCAR complex(GO:0031209)
0.1	0.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	1.3	GO:0042555	MCM complex(GO:0042555)
0.1	0.8	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	2.1	GO:0042627	chylomicron(GO:0042627)
0.1	3.1	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.5	GO:1990393	3M complex(GO:1990393)
0.1	0.5	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.7	GO:0045179	apical cortex(GO:0045179)
0.1	0.6	GO:0005844	polysome(GO:0005844)
0.1	0.7	GO:0031931	TORC1 complex(GO:0031931)
0.1	2.1	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.8	GO:0032039	integrator complex(GO:0032039)
0.1	0.4	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1	0.7	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.4	GO:0032021	NELF complex(GO:0032021)
0.1	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	1.6	GO:0000242	pericentriolar material(GO:0000242)
0.1	1.8	GO:0035371	microtubule plus-end(GO:0035371)
0.1	1.2	GO:0001741	XY body(GO:0001741)
0.1	1.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.4	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.3	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.1	0.6	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.8	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	8.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	0.4	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	0.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.1	1.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.7	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.9	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	0.6	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.7	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.6	GO:0000800	lateral element(GO:0000800)
0.1	0.5	GO:0070652	HAUS complex(GO:0070652)
0.1	0.6	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.7	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	0.3	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.1	0.6	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	1.8	GO:0030673	axolemma(GO:0030673)
0.1	0.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.4	GO:0031415	NatA complex(GO:0031415)
0.1	0.2	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	1.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.6	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.4	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.2	GO:0031213	RSF complex(GO:0031213)
0.1	0.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.5	GO:0000796	condensin complex(GO:0000796)
0.1	2.5	GO:0005871	kinesin complex(GO:0005871)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.5	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	1.5	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	1.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.7	GO:0097227	sperm annulus(GO:0097227)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.0	0.1	GO:0000793	condensed chromosome(GO:0000793)
0.0	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.6	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.8	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.3	GO:0032389	MutLalpha complex(GO:0032389)
0.0	1.0	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	2.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.8	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	1.4	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	2.2	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.3	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.3	GO:0005840	ribosome(GO:0005840)
0.0	1.4	GO:0044815	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0	0.6	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	3.3	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	2.1	GO:0015030	Cajal body(GO:0015030)
0.0	0.2	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.6	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.5	GO:0005922	connexon complex(GO:0005922)
0.0	0.5	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.4	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.4	GO:0044754	autolysosome(GO:0044754)
0.0	5.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.1	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.0	0.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	1.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.0	GO:0071020	post-spliceosomal complex(GO:0071020)
0.0	4.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	1.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	3.2	GO:0043204	perikaryon(GO:0043204)
0.0	1.0	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.7	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.6	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.3	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	0.4	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	7.3	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	1.4	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0060091	kinocilium(GO:0060091)
0.0	0.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.5	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.0	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0	0.5	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.3	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0034709	methylosome(GO:0034709)
0.0	1.3	GO:0000775	chromosome, centromeric region(GO:0000775)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	2.7	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.7	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	1.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	1.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	24.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.7	20.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5	1.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.4	10.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.3	8.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3	21.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.3	22.9	PID RAC1 PATHWAY	RAC1 signaling pathway
0.3	43.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.3	3.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.2	8.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.2	9.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.2	5.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	6.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	8.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.2	12.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.2	2.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.2	6.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	8.1	PID BCR 5PATHWAY	BCR signaling pathway
0.1	7.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	3.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	4.9	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	4.1	PID RAS PATHWAY	Regulation of Ras family activation
0.1	5.4	PID AURORA A PATHWAY	Aurora A signaling
0.1	19.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	0.8	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.6	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	4.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	1.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	0.9	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	1.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.6	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	1.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	1.8	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	6.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	1.9	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	1.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	10.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	2.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	1.5	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	3.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	1.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.6	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	3.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.2	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID TELOMERASE PATHWAY	Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	10.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.5	7.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.4	8.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	2.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	0.9	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	1.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	3.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	3.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.9	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.5	REACTOME GAB1 SIGNALOSOME	Genes involved in GAB1 signalosome
0.0	0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.7	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	1.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	1.2	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	1.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.6	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.4	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	0.5	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	2.2	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	2.5	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.4	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.6	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.2	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	13.9	GO:0005833	hemoglobin complex(GO:0005833)
0.6	3.2	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.6	3.6	GO:1990584	cardiac Troponin complex(GO:1990584)
0.4	1.6	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.3	1.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.3	4.6	GO:0097342	ripoptosome(GO:0097342)
0.2	3.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.2	1.6	GO:0030061	mitochondrial crista(GO:0030061)
0.2	5.0	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	2.4	GO:0033093	Weibel-Palade body(GO:0033093)
0.2	4.2	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2	3.1	GO:0001891	phagocytic cup(GO:0001891)
0.2	0.9	GO:0061689	tricellular tight junction(GO:0061689)
0.1	3.1	GO:0042588	zymogen granule(GO:0042588)
0.1	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.1	1.0	GO:0032437	cuticular plate(GO:0032437)
0.1	5.2	GO:0030027	lamellipodium(GO:0030027)
0.1	0.9	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	2.9	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1	0.8	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.4	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.1	0.4	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.8	GO:0061574	ASAP complex(GO:0061574)
0.1	2.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.3	GO:0031085	BLOC-3 complex(GO:0031085)
0.1	0.4	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	0.3	GO:0071001	U4/U6 snRNP(GO:0071001)
0.1	9.9	GO:0016605	PML body(GO:0016605)
0.1	0.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.7	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	1.0	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	1.3	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.5	GO:0045180	basal cortex(GO:0045180)
0.0	0.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.2	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0	0.3	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.5	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.9	GO:0032982	myosin filament(GO:0032982)
0.0	0.1	GO:0036030	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0	0.2	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	1.0	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.2	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.4	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0000322	storage vacuole(GO:0000322)
0.0	0.2	GO:0097486	multivesicular body lumen(GO:0097486)
0.0	0.8	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.3	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.9	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	2.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.3	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.9	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	1.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.4	GO:0042101	T cell receptor complex(GO:0042101)
0.0	2.6	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.5	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	0.2	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.3	GO:0042627	chylomicron(GO:0042627)
0.0	0.5	GO:0051233	spindle midzone(GO:0051233)
0.0	1.2	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	5.3	GO:0016607	nuclear speck(GO:0016607)
0.0	1.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	3.5	GO:0016604	nuclear body(GO:0016604)
0.0	0.2	GO:0005771	multivesicular body(GO:0005771)
0.0	0.3	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.4	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	0.8	GO:0043195	terminal bouton(GO:0043195)
0.0	19.3	GO:0005887	integral component of plasma membrane(GO:0005887)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.9	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.3	3.7	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	27.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	1.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	0.2	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	8.3	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	1.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	3.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.0	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	4.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	1.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	1.9	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	4.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	2.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.9	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	1.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	2.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.8	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	5.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	5.3	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	1.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.8	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	2.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.6	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	1.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.6	3.2	GO:0004771	sterol esterase activity(GO:0004771)
0.6	2.4	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.6	2.8	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.5	4.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.4	1.3	GO:0051185	FAD transmembrane transporter activity(GO:0015230) coenzyme transporter activity(GO:0051185)
0.4	1.3	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4	1.7	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.4	1.6	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.4	1.2	GO:0004913	interleukin-4 receptor activity(GO:0004913)
0.4	1.1	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.4	1.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3	3.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3	0.9	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	2.0	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.3	3.7	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.3	2.6	GO:0070324	thyroid hormone binding(GO:0070324)
0.3	0.8	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.2	4.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.2	1.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.7	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2	1.4	GO:0042610	CD8 receptor binding(GO:0042610)
0.2	1.3	GO:0003796	lysozyme activity(GO:0003796)
0.2	4.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	0.6	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	0.6	GO:0008859	exoribonuclease II activity(GO:0008859)
0.2	0.8	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.2	1.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	0.6	GO:0047086	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.2	0.6	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.2	10.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.2	1.6	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2	2.0	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.2	0.9	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.2	1.5	GO:0019863	IgE binding(GO:0019863)
0.2	0.5	GO:0052870	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2	1.0	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.2	0.5	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.2	0.8	GO:0043208	glycosphingolipid binding(GO:0043208)
0.2	1.1	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	0.5	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.2	0.6	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.2	0.9	GO:0030492	hemoglobin binding(GO:0030492)
0.2	0.5	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2	2.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.4	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	1.7	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.6	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.1	0.5	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.9	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	1.1	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1	0.5	GO:0047718	indanol dehydrogenase activity(GO:0047718)
0.1	0.5	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	2.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.7	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.8	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.4	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.4	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.1	0.9	GO:0050733	RS domain binding(GO:0050733)
0.1	0.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.9	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	0.9	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.4	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.5	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.4	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1	0.4	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	0.6	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.1	0.5	GO:0008518	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1	0.3	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1	0.3	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.1	0.9	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.8	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.3	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.1	0.3	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	2.0	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	1.0	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.1	2.5	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0035473	lipase binding(GO:0035473)
0.1	0.3	GO:0004796	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1	0.5	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.6	GO:0001851	complement component C3b binding(GO:0001851)
0.1	0.4	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.1	0.3	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.1	2.3	GO:0071837	HMG box domain binding(GO:0071837)
0.1	1.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.3	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.2	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	0.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.1	GO:0001855	complement component C4b binding(GO:0001855)
0.1	0.9	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.6	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.5	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	0.1	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1	0.6	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.1	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.3	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	2.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	0.9	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.5	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1	1.6	GO:0051400	BH domain binding(GO:0051400)
0.1	0.9	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	2.0	GO:0071949	FAD binding(GO:0071949)
0.1	0.6	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	0.3	GO:0016936	galactoside binding(GO:0016936)
0.1	0.2	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.1	1.1	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.3	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1	0.5	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.6	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	0.4	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	0.3	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	0.5	GO:0043199	sulfate binding(GO:0043199)
0.1	0.8	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.6	GO:0000405	bubble DNA binding(GO:0000405)
0.1	2.8	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	4.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	1.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.4	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.3	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.1	0.3	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.1	1.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.3	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.1	1.9	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.4	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.9	GO:0038132	neuregulin binding(GO:0038132)
0.1	1.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.3	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.9	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	1.1	GO:0031996	thioesterase binding(GO:0031996)
0.1	1.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.2	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.3	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.3	GO:0050436	microfibril binding(GO:0050436)
0.1	0.4	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.4	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.8	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.5	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	1.4	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.1	0.8	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.1	1.5	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.5	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.3	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.1	0.2	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.6	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.4	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.8	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.3	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1	0.2	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.1	2.7	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.1	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.8	GO:0031005	filamin binding(GO:0031005)
0.1	0.3	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	1.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.3	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.1	1.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	0.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	1.3	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	1.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.0	0.6	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.7	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.2	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0	0.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	1.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.5	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.3	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	2.0	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.4	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:0043295	glutathione binding(GO:0043295)
0.0	1.3	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	1.8	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.0	1.0	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.5	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.4	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	1.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.0	3.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0005549	odorant binding(GO:0005549)
0.0	0.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.6	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.3	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.6	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0	0.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.4	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.3	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.6	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	1.0	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.4	GO:0097016	L27 domain binding(GO:0097016)
0.0	1.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0	0.6	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0015087	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.2	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.1	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.0	0.4	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.7	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.4	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	1.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.3	GO:0035242	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.0	0.1	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	1.9	GO:0035064	methylated histone binding(GO:0035064)
0.0	3.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	2.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	1.3	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.8	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.3	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.3	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	1.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	1.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0098505	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	1.7	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.1	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0004979	beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0	0.2	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	1.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.5	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.7	GO:0004540	ribonuclease activity(GO:0004540)
0.0	0.6	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.2	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.2	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.6	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0031489	myosin V binding(GO:0031489)
0.0	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	1.7	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.3	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.7	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	1.3	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.7	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.1	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.7	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.3	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.0	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	1.9	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	0.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.5	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.4	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.1	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.0	GO:0050135	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0	0.1	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.3	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.2	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0	0.2	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.3	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	290.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
1.2	17.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
1.1	56.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.8	16.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.8	58.2	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.7	2.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.7	9.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.6	16.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.6	11.6	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.4	9.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.3	18.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.3	9.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	10.4	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.3	5.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3	8.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3	5.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	1.7	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3	6.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	2.8	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	6.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	1.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	2.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	5.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2	9.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	3.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	8.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	2.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	12.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	1.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	11.3	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.1	6.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	9.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	5.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	1.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	2.5	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.1	1.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	4.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	1.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	1.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	1.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.6	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	2.2	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.0	1.1	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	2.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.1	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.9	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	2.0	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	5.6	GO:0019770	IgG receptor activity(GO:0019770)
0.4	2.9	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.3	1.6	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3	2.1	GO:0001849	complement component C1q binding(GO:0001849)
0.3	1.3	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.2	1.0	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2	1.1	GO:0090554	phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1	0.7	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1	1.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	1.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	1.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	1.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.6	GO:0050692	DBD domain binding(GO:0050692)
0.1	0.2	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.4	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	1.7	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.2	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1	5.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	1.0	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.2	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0	0.2	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.0	0.3	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.1	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.3	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.5	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	2.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.5	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	1.1	GO:0051087	chaperone binding(GO:0051087)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	10.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4	4.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	9.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	4.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	5.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.3	5.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	1.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	7.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	1.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	3.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	0.6	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	2.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.5	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	1.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.9	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.2	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.1	1.0	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	3.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	3.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	4.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	5.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	3.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	2.0	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	1.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	0.6	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.6	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.1	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1	1.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.7	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	0.7	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	5.8	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.1	0.8	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	5.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	0.8	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.9	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	1.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.5	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.9	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.6	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.5	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.6	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	2.3	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	2.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.0	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	1.3	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.7	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.4	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	0.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.8	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.1	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.0	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	1.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.6	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.2	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	1.1	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.5	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	0.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	2.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	1.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	10.5	GO:0048611	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
2.9	8.6	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
2.4	7.3	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
2.3	18.5	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
1.4	4.2	GO:0060296	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.3	4.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
1.2	3.7	GO:0097359	UDP-glucosylation(GO:0097359)
0.9	2.6	GO:0001300	chronological cell aging(GO:0001300)
0.9	4.3	GO:0019348	dolichol metabolic process(GO:0019348)
0.8	2.5	GO:0043311	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.8	4.1	GO:0002084	protein depalmitoylation(GO:0002084)
0.8	2.5	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.8	0.8	GO:1900195	positive regulation of oocyte maturation(GO:1900195)
0.8	3.2	GO:0032218	riboflavin transport(GO:0032218)
0.8	0.8	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.8	5.5	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.8	3.1	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
0.7	2.8	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.7	0.7	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.7	2.7	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.7	2.0	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.7	8.2	GO:0046051	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.7	3.3	GO:0030047	actin modification(GO:0030047)
0.6	3.2	GO:1904579	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.6	2.5	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.6	1.9	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.6	1.8	GO:0034227	tRNA thio-modification(GO:0034227)
0.6	1.8	GO:0060166	olfactory pit development(GO:0060166)
0.6	1.8	GO:1900244	positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.6	0.6	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.6	2.3	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.6	5.0	GO:0006531	aspartate metabolic process(GO:0006531)
0.5	1.6	GO:0042350	GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.5	1.6	GO:0006624	vacuolar protein processing(GO:0006624)
0.5	1.6	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.5	3.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.5	2.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5	4.0	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.5	2.9	GO:0001692	histamine metabolic process(GO:0001692)
0.5	3.9	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.5	1.9	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.5	3.3	GO:0006449	regulation of translational termination(GO:0006449)
0.5	1.9	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.4	1.3	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.4	1.3	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.4	1.3	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.4	3.4	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.4	1.7	GO:0016074	snoRNA metabolic process(GO:0016074)
0.4	0.4	GO:2000157	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.4	2.1	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.4	1.2	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.4	1.2	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.4	4.4	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.4	2.0	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.4	1.2	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.4	2.0	GO:0098502	DNA dephosphorylation(GO:0098502)
0.4	1.1	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4	2.3	GO:0051414	response to cortisol(GO:0051414)
0.4	2.7	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.4	3.4	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.4	2.3	GO:0051013	microtubule severing(GO:0051013)
0.4	1.5	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.4	3.4	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.4	9.0	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.4	0.4	GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4	1.8	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.4	2.2	GO:0070475	rRNA base methylation(GO:0070475)
0.4	1.1	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4	1.4	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.4	0.4	GO:0034614	cellular response to reactive oxygen species(GO:0034614)
0.3	3.8	GO:0006983	ER overload response(GO:0006983)
0.3	1.4	GO:0021539	subthalamus development(GO:0021539)
0.3	1.0	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.3	5.5	GO:0043248	proteasome assembly(GO:0043248)
0.3	1.4	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.3	2.0	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.3	1.0	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.3	1.0	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.3	0.7	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.3	0.3	GO:1990502	dense core granule maturation(GO:1990502)
0.3	2.2	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3	4.5	GO:0000338	protein deneddylation(GO:0000338)
0.3	0.9	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.3	2.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.3	0.6	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.3	1.8	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3	5.0	GO:0071285	cellular response to lithium ion(GO:0071285)
0.3	0.9	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.3	0.6	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.3	7.0	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.3	1.4	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3	0.3	GO:0071030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.3	0.6	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3	0.6	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.3	0.3	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.3	1.6	GO:0042713	sperm ejaculation(GO:0042713)
0.3	2.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.3	2.6	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.3	4.0	GO:0045116	protein neddylation(GO:0045116)
0.3	2.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2	1.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.2	1.0	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
0.2	0.7	GO:0033341	regulation of collagen binding(GO:0033341)
0.2	1.0	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2	4.6	GO:0007220	Notch receptor processing(GO:0007220)
0.2	2.2	GO:0031167	rRNA methylation(GO:0031167)
0.2	5.5	GO:0044804	nucleophagy(GO:0044804)
0.2	0.7	GO:0032707	negative regulation of interleukin-23 production(GO:0032707)
0.2	1.6	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2	2.1	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.2	0.7	GO:0006597	spermine biosynthetic process(GO:0006597)
0.2	3.9	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2	1.8	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.2	0.7	GO:0031938	regulation of chromatin silencing at telomere(GO:0031938)
0.2	7.4	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.2	3.8	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.2	1.1	GO:0051036	regulation of endosome size(GO:0051036)
0.2	1.3	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.2	6.6	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.2	0.4	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2	3.7	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.2	1.7	GO:0007000	nucleolus organization(GO:0007000)
0.2	0.9	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.2	0.6	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.2	1.1	GO:0019323	pentose catabolic process(GO:0019323)
0.2	1.2	GO:1904721	negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2	6.8	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.2	2.0	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2	0.8	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2	0.6	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.2	0.2	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.2	3.2	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.2	2.0	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	1.2	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.2	1.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2	8.9	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2	3.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	1.9	GO:0045176	apical protein localization(GO:0045176)
0.2	0.8	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2	0.6	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2	1.1	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.2	2.0	GO:2000582	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2	0.5	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
0.2	0.5	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.2	2.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.7	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2	0.5	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.2	1.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.2	1.8	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.2	2.1	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.2	0.4	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.2	0.7	GO:1903936	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.2	0.4	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.2	1.1	GO:0039526	suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.2	1.9	GO:0051601	exocyst localization(GO:0051601)
0.2	5.7	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2	0.9	GO:0072313	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.2	0.5	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.2	0.5	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2	0.8	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2	0.2	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2	1.6	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.2	0.5	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2	1.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.2	1.3	GO:0035268	protein mannosylation(GO:0035268)
0.2	2.1	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.2	1.4	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2	5.0	GO:0070897	DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.2	1.0	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2	0.9	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.2	4.1	GO:0060325	face morphogenesis(GO:0060325)
0.2	3.7	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2	0.6	GO:0060849	radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2	0.6	GO:0070295	renal water absorption(GO:0070295)
0.2	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.2	2.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.3	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.1	1.0	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.6	GO:0061724	lipophagy(GO:0061724) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1	0.9	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.1	0.4	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.4	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1	1.2	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	1.2	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.4	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	1.7	GO:0046415	urate metabolic process(GO:0046415)
0.1	0.7	GO:0021553	olfactory nerve development(GO:0021553)
0.1	0.6	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1	1.7	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	5.3	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.1	0.7	GO:0006041	glucosamine metabolic process(GO:0006041) glucose 1-phosphate metabolic process(GO:0019255)
0.1	0.3	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1	2.0	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	0.4	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1	0.8	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.1	0.6	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.1	0.5	GO:1904688	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1	3.3	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.1	0.5	GO:0031063	regulation of histone deacetylation(GO:0031063)
0.1	1.2	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1	0.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.9	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	1.8	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.1	1.2	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1	0.7	GO:0097338	response to clozapine(GO:0097338)
0.1	0.7	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.1	0.8	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.1	1.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.1	1.6	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	0.8	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.4	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	6.1	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.1	0.8	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	9.7	GO:0006415	translational termination(GO:0006415)
0.1	3.8	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1	0.4	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1	0.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.4	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.4	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1	0.1	GO:0046755	viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1	0.5	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.1	9.5	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1	1.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1	2.8	GO:0006829	zinc II ion transport(GO:0006829)
0.1	0.6	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	1.8	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	2.2	GO:0032607	interferon-alpha production(GO:0032607)
0.1	0.9	GO:0001878	response to yeast(GO:0001878)
0.1	1.6	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.1	0.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.1	0.9	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	0.5	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	0.7	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.8	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.3	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	1.5	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	0.3	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.5	GO:0000012	single strand break repair(GO:0000012)
0.1	1.2	GO:2000111	senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.1	1.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.1	0.3	GO:0061038	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) uterus morphogenesis(GO:0061038) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1	0.5	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1	3.4	GO:0090383	phagosome acidification(GO:0090383)
0.1	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	0.8	GO:0016559	peroxisome fission(GO:0016559)
0.1	0.6	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)
0.1	2.8	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.1	0.8	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.1	0.9	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.2	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	0.4	GO:0070836	caveola assembly(GO:0070836)
0.1	0.8	GO:0002934	desmosome organization(GO:0002934)
0.1	0.8	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.6	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.1	4.4	GO:0008038	neuron recognition(GO:0008038)
0.1	1.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.1	6.9	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	0.7	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	3.6	GO:1901998	toxin transport(GO:1901998)
0.1	0.3	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	0.8	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1	1.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	0.3	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.1	0.1	GO:0072708	response to sorbitol(GO:0072708)
0.1	1.4	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.4	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1	0.8	GO:0006744	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
0.1	0.3	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1	0.2	GO:0046502	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1	2.7	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.1	1.9	GO:0030539	male genitalia development(GO:0030539)
0.1	0.8	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	7.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	0.4	GO:0032252	secretory granule localization(GO:0032252)
0.1	0.4	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.1	0.3	GO:0061743	motor learning(GO:0061743)
0.1	0.2	GO:0015747	urate transport(GO:0015747)
0.1	0.5	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.1	0.6	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.1	0.8	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	0.2	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.5	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	0.2	GO:2000705	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1	0.2	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1	0.3	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.1	1.7	GO:0006465	signal peptide processing(GO:0006465)
0.1	0.7	GO:0009249	protein lipoylation(GO:0009249)
0.1	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	4.9	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	5.1	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1	0.2	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1	0.6	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	0.2	GO:0032465	regulation of cytokinesis(GO:0032465)
0.1	1.3	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	0.3	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.5	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	0.4	GO:0048278	vesicle docking(GO:0048278)
0.1	0.8	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	1.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.5	GO:0070535	negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	2.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	0.1	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1	2.7	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.1	0.2	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.1	0.4	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1	0.2	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1	0.6	GO:0023035	CD40 signaling pathway(GO:0023035)
0.1	0.2	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	1.8	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	0.1	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	0.4	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.1	5.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	1.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	9.3	GO:0043487	regulation of RNA stability(GO:0043487)
0.1	0.1	GO:0043696	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1	0.2	GO:0022616	DNA strand elongation involved in DNA replication(GO:0006271) DNA strand elongation(GO:0022616)
0.1	0.3	GO:0042247	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1	1.9	GO:0006903	vesicle targeting(GO:0006903)
0.1	1.3	GO:0006895	Golgi to endosome transport(GO:0006895)
0.1	0.9	GO:0006105	succinate metabolic process(GO:0006105)
0.1	0.7	GO:0006265	DNA topological change(GO:0006265)
0.1	0.5	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.4	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	3.0	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	1.1	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1	0.4	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.2	GO:0097527	T cell extravasation(GO:0072683) necroptotic signaling pathway(GO:0097527)
0.1	0.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.3	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.3	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	0.2	GO:0071649	regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1	0.3	GO:0010002	cardioblast differentiation(GO:0010002)
0.1	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.1	0.6	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1	0.3	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.1	2.9	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.1	2.9	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.6	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	1.0	GO:0031033	myosin filament organization(GO:0031033)
0.1	0.9	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	1.3	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.1	0.8	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1	2.3	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.9	GO:0070586	cell-cell adhesion involved in gastrulation(GO:0070586)
0.1	0.1	GO:0033081	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1	0.2	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.4	GO:0090042	tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.1	1.5	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1	0.9	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1	0.2	GO:1904749	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.1	0.1	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1	1.1	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1	0.5	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.1	0.1	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1	0.4	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.1	0.2	GO:1902309	regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	0.1	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) response to glycoprotein(GO:1904587)
0.1	0.7	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.1	1.8	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.1	2.6	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.2	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1	0.4	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.8	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1	0.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.3	GO:0071774	response to fibroblast growth factor(GO:0071774)
0.1	0.7	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.1	0.2	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.1	0.2	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.1	0.5	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1	0.5	GO:0051665	membrane raft localization(GO:0051665)
0.1	0.6	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.2	GO:0070370	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.5	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.9	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.5	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.0	0.3	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.2	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.1	GO:0044827	modulation by host of viral genome replication(GO:0044827)
0.0	0.1	GO:0032418	lysosome localization(GO:0032418)
0.0	0.2	GO:0010748	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.0	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.2	GO:1903350	response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0	1.1	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.5	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.7	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0	0.2	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.2	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.0	2.8	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.7	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0	0.2	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0	0.1	GO:0019046	release from viral latency(GO:0019046)
0.0	0.4	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0	0.1	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.0	1.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.2	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.3	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.3	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	1.3	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	1.3	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.4	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.5	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	0.1	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.5	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.1	GO:0010833	telomere maintenance via telomere lengthening(GO:0010833)
0.0	0.1	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.4	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.5	GO:0010714	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.3	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.0	0.2	GO:1901727	positive regulation of deacetylase activity(GO:0090045) positive regulation of histone deacetylase activity(GO:1901727)
0.0	5.4	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	1.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.2	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.4	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	3.5	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	1.6	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.6	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.4	GO:0019614	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.2	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.2	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	1.0	GO:0030316	osteoclast differentiation(GO:0030316)
0.0	0.8	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.3	GO:1903204	negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0	0.9	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.2	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.3	GO:0015825	L-serine transport(GO:0015825)
0.0	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.4	GO:0006544	glycine metabolic process(GO:0006544)
0.0	0.9	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.3	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.4	GO:1902186	regulation of viral release from host cell(GO:1902186)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.8	GO:0010596	negative regulation of endothelial cell migration(GO:0010596)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.1	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	0.2	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:0001881	receptor recycling(GO:0001881)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0002880	microglial cell activation involved in immune response(GO:0002282) chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0	0.3	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.8	GO:0035904	aorta development(GO:0035904)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.7	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.0	0.5	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	1.0	GO:0042407	cristae formation(GO:0042407)
0.0	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.5	GO:0031114	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.2	GO:1901222	regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0	0.7	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.4	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	7.7	GO:0043687	post-translational protein modification(GO:0043687)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.6	GO:0072348	sulfur compound transport(GO:0072348)
0.0	0.2	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.0	0.0	GO:0097502	mannosylation(GO:0097502)
0.0	0.8	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	1.9	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.1	GO:0048793	pronephros development(GO:0048793)
0.0	0.4	GO:0017004	cytochrome complex assembly(GO:0017004)
0.0	0.1	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.0	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.1	GO:0090493	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.0	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.0	0.8	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.1	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.1	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.9	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.0	0.7	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.5	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.4	GO:0097150	neuronal stem cell population maintenance(GO:0097150)
0.0	0.1	GO:0018008	N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.0	0.4	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.0	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.2	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.7	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.0	0.2	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.1	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.2	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	1.0	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.2	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.1	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0	0.1	GO:0019530	taurine metabolic process(GO:0019530) taurine biosynthetic process(GO:0042412)
0.0	0.2	GO:0030238	male sex determination(GO:0030238)
0.0	1.0	GO:0032526	response to retinoic acid(GO:0032526)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.4	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.5	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.1	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.5	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.8	GO:0007041	lysosomal transport(GO:0007041)
0.0	0.1	GO:0044144	regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0	0.2	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.2	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.3	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	2.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:2001234	negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0003341	cilium movement(GO:0003341)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.1	GO:0010712	regulation of collagen metabolic process(GO:0010712) regulation of multicellular organismal metabolic process(GO:0044246)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.2	GO:0031643	positive regulation of myelination(GO:0031643)
0.0	0.0	GO:0070781	response to biotin(GO:0070781)
0.0	0.3	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.3	GO:0050821	protein stabilization(GO:0050821)
0.0	0.0	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.4	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	1.2	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.0	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.0	GO:0031627	telomeric loop formation(GO:0031627)
0.0	0.1	GO:0042073	intraciliary transport(GO:0042073)
0.0	0.6	GO:0060563	neuroepithelial cell differentiation(GO:0060563)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.6	GO:0030500	regulation of bone mineralization(GO:0030500)
0.0	0.3	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.4	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.4	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	5.2	GO:0006936	muscle contraction(GO:0006936)
0.0	0.5	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.9	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.5	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0090234	regulation of kinetochore assembly(GO:0090234)
0.0	0.3	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.1	GO:0033561	regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0	0.0	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.3	GO:0099537	chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916) trans-synaptic signaling(GO:0099537)
0.0	0.0	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0	0.3	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.3	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	2.1	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.5	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.2	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0	0.2	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.0	GO:1904995	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	1.0	GO:0046578	regulation of Ras protein signal transduction(GO:0046578)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0042269	regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0	0.2	GO:0070207	protein homotrimerization(GO:0070207)
0.0	1.2	GO:0006457	protein folding(GO:0006457)
0.0	0.1	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.0	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0006119	oxidative phosphorylation(GO:0006119)
0.0	0.5	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0	0.2	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0005607	laminin-2 complex(GO:0005607)
0.1	0.9	GO:0071953	elastic fiber(GO:0071953)
0.1	0.2	GO:0034685	integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.5	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	1.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.9	GO:0032982	myosin filament(GO:0032982)
0.0	0.2	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.1	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0035838	growing cell tip(GO:0035838)
0.0	0.4	GO:0032433	filopodium tip(GO:0032433)
0.0	0.4	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	3.5	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.1	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	3.5	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.1	GO:0000815	ESCRT III complex(GO:0000815)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	1.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	1.1	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.8	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.7	2.1	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
0.6	1.7	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.4	1.3	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.4	1.3	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.4	1.9	GO:0038051	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4	3.9	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4	1.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.4	1.1	GO:0015616	DNA translocase activity(GO:0015616)
0.3	6.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.3	6.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.3	1.0	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.3	5.0	GO:0031996	thioesterase binding(GO:0031996)
0.3	3.0	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.3	1.1	GO:0035651	AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.3	1.1	GO:0038025	reelin receptor activity(GO:0038025)
0.3	1.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3	1.0	GO:0035939	microsatellite binding(GO:0035939)
0.2	0.7	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2	0.7	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.2	1.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2	0.2	GO:0032427	GBD domain binding(GO:0032427)
0.2	1.3	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.2	0.7	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2	0.6	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2	0.6	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.2	1.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	1.8	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2	0.6	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.2	1.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2	0.6	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.2	1.7	GO:0015288	porin activity(GO:0015288)
0.2	0.8	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	1.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.2	1.5	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.2	0.7	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2	0.7	GO:0015350	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.2	1.0	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.2	1.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.2	0.7	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2	1.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.2	0.8	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2	0.8	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2	0.5	GO:0070364	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.2	1.4	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.2	0.6	GO:0097100	supercoiled DNA binding(GO:0097100)
0.2	0.6	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2	0.5	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.2	1.1	GO:0001515	opioid peptide activity(GO:0001515)
0.2	0.8	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	0.4	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	1.3	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	0.6	GO:0031493	nucleosomal histone binding(GO:0031493)
0.1	0.4	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	0.9	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.6	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	0.9	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701)
0.1	0.4	GO:0097677	STAT family protein binding(GO:0097677)
0.1	0.9	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	0.8	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	1.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.3	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
0.1	0.6	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.1	0.4	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	0.4	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	1.7	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.4	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	1.3	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.4	GO:0033149	FFAT motif binding(GO:0033149)
0.1	0.4	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	0.9	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	0.4	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.1	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1	1.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	0.5	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.1	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	0.4	GO:0004137	deoxycytidine kinase activity(GO:0004137)
0.1	0.5	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.1	0.4	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
0.1	1.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.7	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	1.9	GO:0004526	ribonuclease P activity(GO:0004526)
0.1	0.5	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.1	1.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.8	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.1	0.5	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	2.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.5	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	5.8	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.9	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.3	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.1	1.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.3	GO:0032090	Pyrin domain binding(GO:0032090)
0.1	0.4	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.1	0.3	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1	0.3	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.3	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1	0.3	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	1.6	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1	0.8	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.4	GO:0032143	single thymine insertion binding(GO:0032143)
0.1	0.3	GO:0070888	E-box binding(GO:0070888)
0.1	3.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.6	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.9	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.4	GO:0016504	peptidase activator activity(GO:0016504)
0.1	1.4	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.6	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.5	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.8	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	1.2	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	0.5	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	1.6	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	1.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.6	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	0.9	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.3	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1	1.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	1.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.1	GO:0005330	dopamine:sodium symporter activity(GO:0005330)
0.1	0.3	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1	0.5	GO:0030492	hemoglobin binding(GO:0030492)
0.1	1.3	GO:0043295	glutathione binding(GO:0043295)
0.1	0.8	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.1	0.3	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1	0.9	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.1	0.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.1	10.6	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	0.8	GO:0032051	clathrin light chain binding(GO:0032051)
0.1	0.4	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	0.3	GO:0004802	transketolase activity(GO:0004802)
0.1	0.7	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.1	0.4	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	0.5	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.3	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	2.2	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	0.2	GO:0046921	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1	0.4	GO:1990460	leptin receptor binding(GO:1990460)
0.1	1.7	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.7	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	0.1	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.7	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	0.5	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.6	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1	1.5	GO:0030515	snoRNA binding(GO:0030515)
0.1	0.3	GO:0051184	heme transporter activity(GO:0015232) cofactor transporter activity(GO:0051184)
0.1	0.3	GO:0004074	biliverdin reductase activity(GO:0004074)
0.1	0.4	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.6	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.2	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	0.9	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	0.5	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.5	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	1.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.1	0.2	GO:0031859	platelet activating factor receptor binding(GO:0031859)
0.1	0.5	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1	1.0	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.6	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.4	GO:0050543	icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1	0.4	GO:0043532	angiostatin binding(GO:0043532)
0.1	0.5	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.3	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	0.3	GO:0002054	nucleobase binding(GO:0002054)
0.1	1.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0070404	NADH binding(GO:0070404)
0.1	0.8	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.2	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.2	GO:0001181	transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1	0.2	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.4	GO:0004645	phosphorylase activity(GO:0004645)
0.1	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.2	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	1.0	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	1.9	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.3	GO:0048256	flap endonuclease activity(GO:0048256)
0.1	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.4	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	0.4	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.2	GO:0003978	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1	0.2	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.1	0.3	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.4	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.1	0.3	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	2.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.3	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.2	GO:0015235	cobalamin transporter activity(GO:0015235)
0.1	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.1	3.1	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.1	0.6	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.1	0.4	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.2	GO:0017130	poly(C) RNA binding(GO:0017130)
0.1	1.0	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	1.2	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1	1.2	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899)
0.1	0.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.6	GO:0016595	glutamate binding(GO:0016595)
0.1	0.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.2	GO:0008940	nitrate reductase activity(GO:0008940)
0.1	0.2	GO:0004766	spermidine synthase activity(GO:0004766)
0.1	0.7	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	1.2	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.6	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.6	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.2	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.5	GO:0048156	tau protein binding(GO:0048156)
0.1	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.2	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.3	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.3	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.7	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	0.4	GO:1990446	U1 snRNP binding(GO:1990446)
0.1	0.2	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.1	0.3	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	0.5	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	2.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.2	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0	0.4	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.7	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	1.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.8	GO:0032451	demethylase activity(GO:0032451)
0.0	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.2	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.2	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.0	0.3	GO:0001851	complement component C3b binding(GO:0001851) ICAM-3 receptor activity(GO:0030369)
0.0	4.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	1.5	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.1	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.6	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.7	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.6	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.2	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.2	GO:0046592	polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0	0.5	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	3.5	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.1	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.0	7.2	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.2	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0016781	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0	0.1	GO:0047325	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.8	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.0	0.9	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.4	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.2	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.5	GO:0031386	protein tag(GO:0031386)
0.0	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.3	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	0.2	GO:0015923	mannosidase activity(GO:0015923)
0.0	0.2	GO:0016829	lyase activity(GO:0016829)
0.0	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	1.1	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	1.6	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.5	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.8	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.2	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.4	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.8	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0016979	lipoate-protein ligase activity(GO:0016979)
0.0	0.1	GO:0004960	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0	0.1	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	1.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.9	GO:0031489	myosin V binding(GO:0031489)
0.0	0.3	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0008235	aminopeptidase activity(GO:0004177) metalloexopeptidase activity(GO:0008235)
0.0	0.2	GO:0008443	phosphofructokinase activity(GO:0008443)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	1.3	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	0.3	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.5	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.2	GO:0046979	TAP2 binding(GO:0046979)
0.0	0.1	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.2	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.2	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.5	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.8	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	1.0	GO:0000049	tRNA binding(GO:0000049)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.1	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.2	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.0	1.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.6	GO:0033558	protein deacetylase activity(GO:0033558)
0.0	0.3	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.9	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	1.3	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.4	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.4	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	1.1	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.4	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.5	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0	0.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.0	0.7	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	5.0	GO:0061630	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	1.0	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.0	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.0	0.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.5	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.8	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.4	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.6	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.5	GO:0046915	transition metal ion transmembrane transporter activity(GO:0046915)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	1.1	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.1	GO:0001632	leukotriene B4 receptor activity(GO:0001632)
0.0	0.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.2	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.3	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.3	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.1	GO:0035326	enhancer binding(GO:0035326)
0.0	0.4	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.2	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.1	GO:1903136	cuprous ion binding(GO:1903136)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0004905	type I interferon receptor activity(GO:0004905)
0.0	0.2	GO:0005272	sodium channel activity(GO:0005272)
0.0	3.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.7	GO:1901505	carbohydrate derivative transporter activity(GO:1901505)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.6	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.3	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.5	GO:0003951	NAD+ kinase activity(GO:0003951)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.2	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	0.2	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.0	0.2	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0016209	antioxidant activity(GO:0016209)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.3	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.1	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.4	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.2	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.8	GO:0008026	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.1	GO:0016803	epoxide hydrolase activity(GO:0004301) ether hydrolase activity(GO:0016803)
0.0	0.2	GO:0005537	mannose binding(GO:0005537)
0.0	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.6	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.2	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.0	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.3	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:0071936	coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.3	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.3	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.2	GO:0016917	GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0	0.2	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.0	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.1	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0	0.0	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.3	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.4	GO:0015179	L-amino acid transmembrane transporter activity(GO:0015179)
0.0	0.1	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	19.5	GO:0043259	laminin-10 complex(GO:0043259)
3.8	11.3	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
3.0	12.1	GO:0045160	myosin I complex(GO:0045160)
3.0	9.1	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
2.9	14.3	GO:0032449	CBM complex(GO:0032449)
2.7	41.2	GO:0005916	fascia adherens(GO:0005916)
2.7	13.4	GO:0071148	TEAD-1-YAP complex(GO:0071148)
2.5	10.2	GO:0071664	beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
2.3	6.9	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
2.1	10.5	GO:0071797	LUBAC complex(GO:0071797)
2.0	16.3	GO:0016012	sarcoglycan complex(GO:0016012)
1.9	9.5	GO:0005899	insulin receptor complex(GO:0005899)
1.9	24.7	GO:0097470	ribbon synapse(GO:0097470)
1.9	20.6	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
1.6	11.2	GO:0036021	endolysosome lumen(GO:0036021)
1.6	4.7	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
1.6	29.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
1.5	9.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
1.4	8.5	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
1.4	15.1	GO:0097443	sorting endosome(GO:0097443)
1.4	5.5	GO:0031673	H zone(GO:0031673)
1.3	3.8	GO:0005588	collagen type V trimer(GO:0005588)
1.2	1.2	GO:0005683	U7 snRNP(GO:0005683)
1.2	4.8	GO:0070695	FHF complex(GO:0070695)
1.2	10.6	GO:0005955	calcineurin complex(GO:0005955)
1.2	3.5	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
1.1	6.8	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
1.1	1.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
1.1	2.2	GO:0016600	flotillin complex(GO:0016600)
1.0	5.2	GO:0097513	myosin II filament(GO:0097513)
1.0	10.4	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
1.0	3.1	GO:0070435	Shc-EGFR complex(GO:0070435)
1.0	9.2	GO:1990761	growth cone lamellipodium(GO:1990761)
1.0	3.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
1.0	4.0	GO:0030485	smooth muscle contractile fiber(GO:0030485)
1.0	14.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.0	9.8	GO:0071953	elastic fiber(GO:0071953)
1.0	13.5	GO:0031209	SCAR complex(GO:0031209)
1.0	1.9	GO:0016011	dystroglycan complex(GO:0016011)
1.0	19.2	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
1.0	8.6	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.9	10.2	GO:0005614	interstitial matrix(GO:0005614)
0.9	4.5	GO:1990393	3M complex(GO:1990393)
0.9	27.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.9	4.4	GO:0032420	stereocilium(GO:0032420)
0.9	5.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.8	3.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.8	2.5	GO:1903349	omegasome membrane(GO:1903349)
0.8	9.1	GO:0042612	MHC class I protein complex(GO:0042612)
0.8	6.5	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.8	3.2	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.8	3.2	GO:0097224	sperm connecting piece(GO:0097224)
0.8	7.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.8	2.3	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.8	78.4	GO:0005604	basement membrane(GO:0005604)
0.8	2.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.7	2.2	GO:0043218	compact myelin(GO:0043218)
0.7	1.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.7	2.8	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.7	5.5	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.7	2.7	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.7	2.7	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.7	7.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.7	3.3	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.7	6.5	GO:0097413	Lewy body(GO:0097413)
0.7	4.6	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.7	1.3	GO:1990812	growth cone filopodium(GO:1990812)
0.6	2.6	GO:0005797	Golgi medial cisterna(GO:0005797)
0.6	3.2	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.6	8.9	GO:0008091	spectrin(GO:0008091)
0.6	24.1	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.6	1.9	GO:0072563	endothelial microparticle(GO:0072563)
0.6	6.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.6	12.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.6	1.9	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.6	4.3	GO:0005915	zonula adherens(GO:0005915)
0.6	13.4	GO:0031105	septin complex(GO:0031105)
0.6	4.9	GO:0035976	AP1 complex(GO:0035976)
0.6	2.4	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.6	21.1	GO:0000421	autophagosome membrane(GO:0000421)
0.6	10.6	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.6	4.7	GO:0005593	FACIT collagen trimer(GO:0005593)
0.6	46.3	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.6	4.6	GO:0071438	invadopodium membrane(GO:0071438)
0.6	1.7	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.6	15.9	GO:0031527	filopodium membrane(GO:0031527)
0.6	5.0	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.6	0.6	GO:0032421	stereocilium bundle(GO:0032421)
0.6	17.6	GO:0005685	U1 snRNP(GO:0005685)
0.5	11.5	GO:0042641	actomyosin(GO:0042641)
0.5	1.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.5	19.8	GO:0043034	costamere(GO:0043034)
0.5	40.2	GO:0030175	filopodium(GO:0030175)
0.5	12.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.5	1.1	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5	4.3	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.5	1.6	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.5	1.6	GO:0035189	Rb-E2F complex(GO:0035189)
0.5	7.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.5	2.5	GO:0036128	CatSper complex(GO:0036128)
0.5	1.0	GO:0032584	growth cone membrane(GO:0032584)
0.5	8.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.5	1.5	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.5	1.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.5	46.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.5	1.4	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.5	4.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.5	1.8	GO:0031302	intrinsic component of endosome membrane(GO:0031302)
0.5	0.9	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.4	0.9	GO:0044308	axonal spine(GO:0044308)
0.4	8.9	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4	3.9	GO:1990909	Wnt signalosome(GO:1990909)
0.4	1.7	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.4	5.5	GO:1990023	mitotic spindle midzone(GO:1990023)
0.4	1.7	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.4	113.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.4	6.2	GO:0030478	actin cap(GO:0030478)
0.4	1.2	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.4	1.2	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.4	5.7	GO:0032432	actin filament bundle(GO:0032432)
0.4	2.4	GO:0014802	terminal cisterna(GO:0014802)
0.4	3.2	GO:0070578	RISC-loading complex(GO:0070578)
0.4	14.5	GO:0045178	basal part of cell(GO:0045178)
0.4	1.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.4	2.8	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.4	1.6	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4	2.8	GO:0033269	internode region of axon(GO:0033269)
0.4	4.7	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.4	1.6	GO:0070765	gamma-secretase complex(GO:0070765)
0.4	0.4	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4	46.7	GO:0043202	lysosomal lumen(GO:0043202)
0.4	10.0	GO:0005921	gap junction(GO:0005921)
0.4	6.1	GO:0097225	sperm midpiece(GO:0097225)
0.4	3.4	GO:0005869	dynactin complex(GO:0005869)
0.4	3.0	GO:0045495	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.4	4.1	GO:0060077	inhibitory synapse(GO:0060077)
0.4	66.0	GO:0001726	ruffle(GO:0001726)
0.4	1.8	GO:0044295	axonal growth cone(GO:0044295)
0.4	7.7	GO:0014704	intercalated disc(GO:0014704)
0.4	19.5	GO:0005901	caveola(GO:0005901)
0.4	23.1	GO:1904724	tertiary granule lumen(GO:1904724)
0.4	15.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.4	4.0	GO:0033391	chromatoid body(GO:0033391)
0.4	1.1	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.4	4.3	GO:0033643	host cell part(GO:0033643)
0.4	5.4	GO:0031089	platelet dense granule lumen(GO:0031089)
0.4	3.6	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4	2.5	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.3	25.3	GO:0043195	terminal bouton(GO:0043195)
0.3	2.1	GO:0000124	SAGA complex(GO:0000124)
0.3	2.4	GO:0031045	dense core granule(GO:0031045)
0.3	1.7	GO:0097208	alveolar lamellar body(GO:0097208)
0.3	8.3	GO:0099738	cell cortex region(GO:0099738)
0.3	2.9	GO:0034464	BBSome(GO:0034464)
0.3	3.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.3	6.4	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.3	0.6	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3	0.9	GO:0042788	polysomal ribosome(GO:0042788)
0.3	1.9	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.3	3.7	GO:0030016	myofibril(GO:0030016)
0.3	1.8	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3	7.6	GO:0030057	desmosome(GO:0030057)
0.3	2.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.3	1.2	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.3	1.2	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.3	7.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.3	0.9	GO:1902636	kinociliary basal body(GO:1902636)
0.3	0.9	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.3	0.3	GO:0097454	Schwann cell microvillus(GO:0097454)
0.3	12.2	GO:0001772	immunological synapse(GO:0001772)
0.3	24.1	GO:0005905	clathrin-coated pit(GO:0005905)
0.3	1.8	GO:0002116	semaphorin receptor complex(GO:0002116)
0.3	0.9	GO:0016938	kinesin I complex(GO:0016938)
0.3	3.5	GO:0008385	IkappaB kinase complex(GO:0008385)
0.3	1.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.3	17.6	GO:0055038	recycling endosome membrane(GO:0055038)
0.3	1.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.3	1.7	GO:0030137	COPI-coated vesicle(GO:0030137)
0.3	3.4	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.3	2.0	GO:0033270	paranode region of axon(GO:0033270)
0.3	117.1	GO:0005924	cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.3	0.8	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3	1.1	GO:1990246	uniplex complex(GO:1990246)
0.3	1.9	GO:0000813	ESCRT I complex(GO:0000813)
0.3	2.7	GO:0031528	microvillus membrane(GO:0031528)
0.3	0.5	GO:0042587	glycogen granule(GO:0042587)
0.3	3.2	GO:0071141	SMAD protein complex(GO:0071141)
0.3	40.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.3	19.7	GO:0055037	recycling endosome(GO:0055037)
0.3	1.0	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.3	25.4	GO:0005814	centriole(GO:0005814)
0.2	0.5	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.2	13.7	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2	5.7	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.2	6.7	GO:0005581	collagen trimer(GO:0005581)
0.2	2.3	GO:1904115	axon cytoplasm(GO:1904115)
0.2	1.6	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.2	3.2	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.2	0.9	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	1.8	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.2	0.7	GO:0031430	M band(GO:0031430)
0.2	0.2	GO:0005883	neurofilament(GO:0005883)
0.2	0.9	GO:0030914	STAGA complex(GO:0030914)
0.2	0.6	GO:0098845	postsynaptic endosome(GO:0098845)
0.2	0.8	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.2	6.0	GO:0043198	dendritic shaft(GO:0043198)
0.2	14.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.2	0.6	GO:0000806	Y chromosome(GO:0000806)
0.2	4.5	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.2	1.2	GO:0031143	pseudopodium(GO:0031143)
0.2	2.4	GO:0002102	podosome(GO:0002102)
0.2	1.6	GO:0072546	ER membrane protein complex(GO:0072546)
0.2	2.5	GO:0032994	protein-lipid complex(GO:0032994)
0.2	9.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.2	1.2	GO:1990130	Iml1 complex(GO:1990130)
0.2	1.3	GO:0005787	signal peptidase complex(GO:0005787)
0.2	0.8	GO:0045298	tubulin complex(GO:0045298)
0.2	1.9	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2	0.6	GO:0033565	ESCRT-0 complex(GO:0033565)
0.2	2.8	GO:0016328	lateral plasma membrane(GO:0016328)
0.2	0.4	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.2	0.4	GO:0017119	Golgi transport complex(GO:0017119)
0.2	0.2	GO:0030893	meiotic cohesin complex(GO:0030893)
0.2	2.0	GO:0035686	sperm fibrous sheath(GO:0035686)
0.2	20.1	GO:0031012	extracellular matrix(GO:0031012)
0.2	0.9	GO:0045211	postsynaptic membrane(GO:0045211)
0.2	4.8	GO:0016460	myosin II complex(GO:0016460)
0.2	0.2	GO:0044305	calyx of Held(GO:0044305)
0.2	2.9	GO:0005640	nuclear outer membrane(GO:0005640)
0.2	0.2	GO:0000938	GARP complex(GO:0000938)
0.2	0.8	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	1.0	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	4.4	GO:0097546	ciliary base(GO:0097546)
0.2	0.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	6.3	GO:0005912	adherens junction(GO:0005912)
0.2	0.5	GO:0071020	post-spliceosomal complex(GO:0071020)
0.2	0.3	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2	1.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.2	2.0	GO:0030904	retromer complex(GO:0030904)
0.2	2.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2	0.8	GO:0044232	organelle membrane contact site(GO:0044232)
0.2	1.1	GO:0016589	NURF complex(GO:0016589)
0.2	2.9	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	0.2	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	10.9	GO:0030027	lamellipodium(GO:0030027)
0.1	0.3	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.4	GO:0031251	PAN complex(GO:0031251)
0.1	0.1	GO:0042589	zymogen granule(GO:0042588) zymogen granule membrane(GO:0042589)
0.1	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	0.4	GO:0036398	TCR signalosome(GO:0036398)
0.1	1.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.4	GO:0044327	dendritic spine head(GO:0044327)
0.1	1.9	GO:0043073	germ cell nucleus(GO:0043073)
0.1	0.8	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.3	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1	0.5	GO:0070852	cell body fiber(GO:0070852)
0.1	0.6	GO:0043196	varicosity(GO:0043196)
0.1	0.8	GO:0097433	dense body(GO:0097433)
0.1	6.0	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	2.8	GO:0005902	microvillus(GO:0005902)
0.1	0.5	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	15.7	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1	1.4	GO:0031985	Golgi cisterna(GO:0031985)
0.1	5.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	4.7	GO:0016324	apical plasma membrane(GO:0016324)
0.1	8.0	GO:0005923	bicellular tight junction(GO:0005923)
0.1	0.5	GO:0033263	CORVET complex(GO:0033263)
0.1	0.2	GO:0055087	Ski complex(GO:0055087)
0.1	0.1	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.1	2.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	0.3	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.1	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.1	5.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	1.0	GO:0000242	pericentriolar material(GO:0000242)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	1.0	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.1	4.9	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1	5.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	0.6	GO:1902560	GMP reductase complex(GO:1902560)
0.1	0.7	GO:0005801	cis-Golgi network(GO:0005801)
0.1	0.4	GO:0002177	manchette(GO:0002177)
0.1	1.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	1.0	GO:0036038	MKS complex(GO:0036038)
0.1	0.9	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.3	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	47.5	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.1	0.3	GO:0060076	excitatory synapse(GO:0060076)
0.1	0.2	GO:0042583	chromaffin granule(GO:0042583)
0.1	0.5	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1	1.3	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.4	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.1	0.3	GO:0097361	CIA complex(GO:0097361)
0.1	0.5	GO:0031514	motile cilium(GO:0031514)
0.1	1.2	GO:0035579	specific granule membrane(GO:0035579)
0.1	0.6	GO:0008537	proteasome activator complex(GO:0008537)
0.1	0.3	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	2.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	2.3	GO:0070821	tertiary granule membrane(GO:0070821)
0.1	0.1	GO:0030992	intraciliary transport particle(GO:0030990) intraciliary transport particle B(GO:0030992)
0.1	5.1	GO:0005802	trans-Golgi network(GO:0005802)
0.1	0.1	GO:0030315	T-tubule(GO:0030315)
0.1	0.4	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	0.8	GO:0036452	ESCRT complex(GO:0036452)
0.1	4.4	GO:0030018	Z disc(GO:0030018)
0.1	2.9	GO:0005770	late endosome(GO:0005770)
0.1	0.4	GO:0070847	core mediator complex(GO:0070847)
0.1	0.3	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.1	0.3	GO:0001940	male pronucleus(GO:0001940)
0.1	10.7	GO:0019898	extrinsic component of membrane(GO:0019898)
0.1	0.2	GO:0031091	platelet alpha granule(GO:0031091)
0.1	0.4	GO:0071203	WASH complex(GO:0071203)
0.1	0.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.1	0.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	3.6	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	0.4	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	2.6	GO:0031256	leading edge membrane(GO:0031256)
0.1	0.8	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.1	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	1.8	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.3	GO:0032044	DSIF complex(GO:0032044)
0.1	3.6	GO:0031901	early endosome membrane(GO:0031901)
0.1	0.1	GO:0002139	stereocilia coupling link(GO:0002139)
0.1	8.1	GO:0010008	endosome membrane(GO:0010008)
0.1	0.2	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1	1.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.1	0.5	GO:0002080	acrosomal membrane(GO:0002080)
0.1	0.7	GO:0060170	ciliary membrane(GO:0060170)
0.1	1.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.2	GO:0070876	SOSS complex(GO:0070876)
0.1	0.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	0.7	GO:0008180	COP9 signalosome(GO:0008180)
0.1	0.2	GO:0019012	virion(GO:0019012) virion part(GO:0044423)
0.1	0.1	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.1	2.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	0.2	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.1	0.3	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	49.2	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	0.4	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.2	GO:0071010	U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0	0.0	GO:0005713	recombination nodule(GO:0005713)
0.0	0.1	GO:0031674	I band(GO:0031674)
0.0	1.0	GO:0042383	sarcolemma(GO:0042383)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.0	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.1	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	22.1	GO:0005615	extracellular space(GO:0005615)
0.0	0.4	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	1.1	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.0	GO:0034706	sodium channel complex(GO:0034706)
0.0	10.5	GO:0009986	cell surface(GO:0009986)
0.0	0.3	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.1	GO:0098791	Golgi subcompartment(GO:0098791)
0.0	18.2	GO:0005856	cytoskeleton(GO:0005856)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.1	GO:0030014	CCR4-NOT complex(GO:0030014)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.6	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
1.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.7	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
1.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
1.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.4	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.5	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
2.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.3	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	6.3	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.7	2.8	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.5	1.6	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.5	3.1	GO:0000821	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.5	4.0	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.4	1.4	GO:0001757	somite specification(GO:0001757)
0.3	1.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.2	0.7	GO:0098937	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2	0.8	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.2	1.7	GO:0030091	protein repair(GO:0030091)
0.2	1.7	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.2	0.8	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	1.2	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2	1.3	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2	0.6	GO:0035523	protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1	6.6	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.1	1.1	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.6	GO:0008218	bioluminescence(GO:0008218)
0.1	1.2	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.2	GO:0002456	T cell mediated immunity(GO:0002456)
0.1	0.4	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	3.2	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.1	1.0	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.7	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.5	GO:0097646	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1	0.4	GO:0015866	ADP transport(GO:0015866)
0.0	0.4	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.2	GO:0034334	adherens junction maintenance(GO:0034334)
0.0	0.2	GO:0046967	cytosol to ER transport(GO:0046967)
0.0	1.3	GO:0003016	respiratory system process(GO:0003016)
0.0	1.0	GO:0095500	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0	0.4	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	1.1	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.2	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.1	GO:0009956	radial pattern formation(GO:0009956)
0.0	2.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.2	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.1	GO:0007619	courtship behavior(GO:0007619)
0.0	1.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	1.3	GO:0042116	macrophage activation(GO:0042116)
0.0	0.1	GO:0048165	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0	0.1	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.7	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:1902358	sulfate transmembrane transport(GO:1902358)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0071313	cellular response to caffeine(GO:0071313)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.7	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	3.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	2.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.6	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.9	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.9	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	1.9	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	2.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	2.2	REACTOME KINESINS	Genes involved in Kinesins
0.1	3.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	1.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	1.5	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.1	1.9	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	0.8	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.1	1.0	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.4	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.1	1.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	1.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	0.5	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.1	1.6	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	0.5	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.4	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	4.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	3.5	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	1.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.7	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	2.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.1	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.4	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.6	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	1.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.9	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.5	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.2	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.6	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
1.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.7	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
3.0	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
2.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	8.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	9.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	12.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.9	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	2.8	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	7.3	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	1.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.7	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.7	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.5	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	2.6	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	1.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.5	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.9	32.7	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
5.6	16.9	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.9	5.8	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
1.7	12.2	GO:1990539	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
1.7	5.1	GO:1990922	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.5	12.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
1.4	2.9	GO:0003064	regulation of heart rate by hormone(GO:0003064)
1.2	3.7	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
1.1	7.6	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
1.0	3.0	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.9	3.5	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.9	1.8	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.9	2.6	GO:0021571	rhombomere 5 development(GO:0021571)
0.8	4.2	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.8	3.1	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.8	3.1	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.8	3.1	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.7	3.7	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.7	2.2	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.7	5.7	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.7	2.1	GO:1903413	cellular response to bile acid(GO:1903413)
0.7	2.0	GO:1904404	cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.6	0.6	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.6	3.5	GO:0070458	cellular detoxification of nitrogen compound(GO:0070458)
0.5	0.5	GO:1902961	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.5	1.5	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.5	1.5	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.5	1.4	GO:1904482	response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.5	33.6	GO:0006910	phagocytosis, recognition(GO:0006910)
0.5	1.9	GO:0071461	cellular response to redox state(GO:0071461)
0.4	2.2	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.4	1.8	GO:0001757	somite specification(GO:0001757)
0.4	2.2	GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.4	0.9	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.4	2.2	GO:1901907	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4	1.3	GO:1903925	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4	3.4	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.4	1.3	GO:0036309	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.4	1.2	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.4	1.2	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.4	2.0	GO:0044539	long-chain fatty acid import(GO:0044539)
0.4	3.2	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000343)
0.4	3.6	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.4	1.2	GO:0072229	proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.4	2.3	GO:0006540	glutamate decarboxylation to succinate(GO:0006540)
0.4	2.3	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.4	1.5	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.4	1.5	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.4	1.1	GO:0070997	neuron death(GO:0070997)
0.4	1.9	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.4	1.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.4	1.1	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.4	4.0	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4	2.2	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.4	1.8	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.4	4.3	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.3	1.4	GO:0032954	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3	1.7	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.3	2.3	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.3	0.7	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.3	1.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.3	1.0	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.3	2.6	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.3	1.3	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.3	1.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.3	0.9	GO:0021718	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3	1.6	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3	0.9	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.3	0.9	GO:0030264	nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.3	0.9	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.3	0.9	GO:0042495	detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3	1.8	GO:0016554	cytidine to uridine editing(GO:0016554)
0.3	0.9	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.3	1.5	GO:0009440	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.3	0.9	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3	0.9	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.3	5.2	GO:0035855	megakaryocyte development(GO:0035855)
0.3	0.3	GO:1902995	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.3	1.1	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.3	0.8	GO:0001923	B-1 B cell differentiation(GO:0001923)
0.3	1.4	GO:0001834	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.3	0.3	GO:1902003	regulation of beta-amyloid formation(GO:1902003)
0.3	0.5	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.3	0.3	GO:2000410	regulation of thymocyte migration(GO:2000410)
0.3	0.8	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3	1.3	GO:2001293	malonyl-CoA metabolic process(GO:2001293)
0.3	2.8	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.3	0.8	GO:0036333	hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.3	1.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.3	1.5	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.3	5.6	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.3	2.5	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2	1.0	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.2	1.0	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2	1.5	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.2	3.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.2	1.2	GO:0015862	uridine transport(GO:0015862)
0.2	0.2	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.2	0.7	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.2	0.7	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2	1.4	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.2	0.7	GO:1904647	response to rotenone(GO:1904647)
0.2	1.4	GO:0015811	L-cystine transport(GO:0015811)
0.2	0.9	GO:0002326	B cell lineage commitment(GO:0002326)
0.2	0.2	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.2	2.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2	1.4	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.2	0.5	GO:0007051	spindle organization(GO:0007051)
0.2	3.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.2	1.6	GO:0006642	triglyceride mobilization(GO:0006642)
0.2	3.5	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2	0.7	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.2	1.7	GO:1902302	regulation of potassium ion export(GO:1902302)
0.2	1.9	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.2	0.6	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.2	0.6	GO:0035623	regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.2	1.0	GO:0008637	apoptotic mitochondrial changes(GO:0008637)
0.2	0.4	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.2	0.6	GO:0002634	regulation of germinal center formation(GO:0002634)
0.2	1.0	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.2	3.3	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.2	1.2	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2	0.6	GO:0006404	RNA import into nucleus(GO:0006404)
0.2	1.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2	3.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	0.6	GO:1902809	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2	0.6	GO:0035377	transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2	3.8	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.2	1.2	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
0.2	0.2	GO:0071288	cellular response to mercury ion(GO:0071288)
0.2	0.2	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2	0.4	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.2	1.5	GO:0016139	glycoside catabolic process(GO:0016139)
0.2	0.8	GO:0061743	motor learning(GO:0061743)
0.2	0.4	GO:0045994	positive regulation of translational initiation by iron(GO:0045994)
0.2	0.6	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.2	0.7	GO:0046952	ketone body catabolic process(GO:0046952)
0.2	0.2	GO:0048841	regulation of axon extension involved in axon guidance(GO:0048841)
0.2	0.7	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.2	0.2	GO:0014823	response to activity(GO:0014823)
0.2	1.5	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2	2.7	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.2	0.5	GO:2000611	regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611)
0.2	0.9	GO:0072069	DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.2	0.5	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.2	0.5	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.2	2.3	GO:0070327	thyroid hormone transport(GO:0070327)
0.2	1.4	GO:0045059	positive thymic T cell selection(GO:0045059)
0.2	1.6	GO:2001300	lipoxin metabolic process(GO:2001300)
0.2	0.5	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
0.2	0.5	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2	0.5	GO:0072179	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) nephric duct formation(GO:0072179) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2	0.7	GO:2000314	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2	0.5	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.2	0.5	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.2	0.7	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.2	3.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.2	1.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2	0.5	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2	0.2	GO:0019322	pentose biosynthetic process(GO:0019322)
0.2	1.3	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.2	0.3	GO:0042538	hyperosmotic salinity response(GO:0042538)
0.2	0.5	GO:0072709	cellular response to sorbitol(GO:0072709)
0.2	5.2	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.2	0.5	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2	1.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.2	0.6	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.2	0.3	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2	0.8	GO:0001781	neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031)
0.2	2.0	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.2	0.8	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.2	1.4	GO:0006552	leucine catabolic process(GO:0006552)
0.2	2.9	GO:0051255	spindle midzone assembly(GO:0051255)
0.2	0.6	GO:0036515	serotonergic neuron axon guidance(GO:0036515)
0.2	0.2	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.2	2.6	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2	0.8	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2	0.3	GO:0061010	gall bladder development(GO:0061010)
0.2	0.5	GO:0048850	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.1	3.0	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.9	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1	0.6	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	0.1	GO:0060775	mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1	0.4	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	2.3	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.1	0.4	GO:0050894	determination of affect(GO:0050894)
0.1	0.7	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.1	0.6	GO:0045829	negative regulation of isotype switching(GO:0045829)
0.1	0.4	GO:0048539	bone marrow development(GO:0048539)
0.1	0.4	GO:0046210	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210)
0.1	0.4	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.1	0.6	GO:1901723	visceral serous pericardium development(GO:0061032) negative regulation of glomerular mesangial cell proliferation(GO:0072125) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) negative regulation of glomerulus development(GO:0090194) negative regulation of cell proliferation involved in kidney development(GO:1901723)
0.1	0.6	GO:1902361	mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1	8.7	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.1	1.3	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.1	0.6	GO:0003335	corneocyte development(GO:0003335)
0.1	0.4	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.1	0.4	GO:0071790	spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1	0.1	GO:0035456	response to interferon-beta(GO:0035456)
0.1	1.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.5	GO:0071362	cellular response to ether(GO:0071362)
0.1	0.4	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1	0.8	GO:0006021	inositol biosynthetic process(GO:0006021)
0.1	0.3	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.5	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.1	0.5	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.8	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.1	0.1	GO:0060023	soft palate development(GO:0060023)
0.1	6.8	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	0.3	GO:0003358	noradrenergic neuron development(GO:0003358)
0.1	0.5	GO:0051352	negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1	0.4	GO:0008050	female courtship behavior(GO:0008050)
0.1	0.5	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.1	0.5	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1	0.5	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.1	2.3	GO:0021516	dorsal spinal cord development(GO:0021516)
0.1	0.3	GO:0019751	polyol metabolic process(GO:0019751)
0.1	0.4	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.4	GO:2000307	iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.1	0.1	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1	0.5	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.4	GO:1902499	positive regulation of protein autoubiquitination(GO:1902499)
0.1	1.0	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1	0.4	GO:0001207	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1	0.5	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.1	0.6	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1	3.7	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	1.4	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1	1.4	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1	0.2	GO:0019086	late viral transcription(GO:0019086)
0.1	0.3	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1	0.8	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1	0.5	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.1	0.1	GO:0007603	phototransduction, visible light(GO:0007603)
0.1	0.3	GO:0032900	negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	0.2	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.1	0.2	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1	0.2	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.1	0.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.1	0.4	GO:0048073	regulation of eye pigmentation(GO:0048073)
0.1	0.8	GO:0071315	cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.1	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.5	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1	0.3	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.7	GO:0035799	ureter maturation(GO:0035799)
0.1	0.7	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	0.4	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.1	0.8	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	0.4	GO:0003091	renal water homeostasis(GO:0003091)
0.1	0.6	GO:0010225	response to UV-C(GO:0010225)
0.1	0.4	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.7	GO:0000012	single strand break repair(GO:0000012)
0.1	10.9	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.1	1.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.1	0.8	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.8	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	1.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.5	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.1	1.1	GO:0032310	prostaglandin secretion(GO:0032310)
0.1	0.3	GO:0009258	10-formyltetrahydrofolate catabolic process(GO:0009258)
0.1	0.1	GO:0032425	regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.1	0.6	GO:1902669	positive regulation of axon guidance(GO:1902669)
0.1	0.2	GO:1901523	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1	0.7	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	1.2	GO:0045475	locomotor rhythm(GO:0045475)
0.1	0.1	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.7	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	1.0	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.4	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1	0.6	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	1.0	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.7	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.5	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.1	0.4	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.1	0.6	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	0.8	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.3	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.1	0.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.1	0.3	GO:1904886	beta-catenin destruction complex disassembly(GO:1904886)
0.1	2.2	GO:0045730	respiratory burst(GO:0045730)
0.1	0.4	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	1.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	0.7	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	0.4	GO:1903236	regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1	6.2	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.1	1.2	GO:0016180	snRNA processing(GO:0016180)
0.1	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.4	GO:0010842	retina layer formation(GO:0010842)
0.1	0.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.4	GO:0016240	autophagosome docking(GO:0016240)
0.1	0.3	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.6	GO:0070375	ERK5 cascade(GO:0070375)
0.1	0.5	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.4	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	1.2	GO:1903358	regulation of Golgi organization(GO:1903358)
0.1	0.4	GO:0036343	psychomotor behavior(GO:0036343)
0.1	0.6	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	2.0	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.4	GO:0051754	meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1	1.3	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.1	0.4	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	0.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.6	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	1.2	GO:0019400	alditol metabolic process(GO:0019400)
0.1	0.2	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.1	0.9	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.6	GO:0019321	pentose metabolic process(GO:0019321)
0.1	0.3	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.1	0.3	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	0.7	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.1	0.3	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.1	0.8	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.3	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.1	0.2	GO:0015670	carbon dioxide transport(GO:0015670)
0.1	0.3	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.1	0.9	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.2	GO:0006311	meiotic gene conversion(GO:0006311)
0.1	0.2	GO:1904338	regulation of dopaminergic neuron differentiation(GO:1904338)
0.1	0.3	GO:0044571	[2Fe-2S] cluster assembly(GO:0044571)
0.1	0.3	GO:0072658	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.5	GO:0021853	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.2	GO:2000824	proximal tubule development(GO:0072014) negative regulation of androgen receptor activity(GO:2000824)
0.1	2.0	GO:0016578	histone deubiquitination(GO:0016578)
0.1	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.3	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.1	0.3	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130)
0.1	0.2	GO:0019072	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	0.8	GO:0015886	heme transport(GO:0015886)
0.1	0.2	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	2.0	GO:0033198	response to ATP(GO:0033198)
0.1	0.4	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1	0.3	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1	0.3	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.4	GO:0070383	DNA cytosine deamination(GO:0070383)
0.1	0.3	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1	0.4	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1	0.4	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	2.4	GO:0042100	B cell proliferation(GO:0042100)
0.1	1.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.1	0.3	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.1	0.4	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1	1.2	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1	1.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.1	GO:1903061	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.1	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1	1.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1	0.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	1.1	GO:0019722	calcium-mediated signaling(GO:0019722)
0.1	0.5	GO:0009249	protein lipoylation(GO:0009249)
0.1	0.6	GO:0060482	lobar bronchus development(GO:0060482)
0.1	0.8	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1	5.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	1.6	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.1	2.6	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.1	0.2	GO:0070105	regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1	3.6	GO:0045576	mast cell activation(GO:0045576)
0.1	0.6	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1	0.5	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	1.3	GO:0036297	interstrand cross-link repair(GO:0036297)
0.1	0.3	GO:0009233	menaquinone metabolic process(GO:0009233)
0.1	0.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.1	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1	0.5	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.1	0.3	GO:0006740	NADPH regeneration(GO:0006740)
0.1	0.3	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	1.4	GO:0050779	RNA destabilization(GO:0050779)
0.1	1.6	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1	1.2	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1	0.5	GO:0070673	response to interleukin-18(GO:0070673)
0.1	0.3	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.1	0.6	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.1	0.9	GO:2000637	positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1	0.3	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1	0.1	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.1	0.3	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.1	0.1	GO:0035739	CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
0.1	0.4	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.1	0.1	GO:0043096	purine nucleobase salvage(GO:0043096)
0.1	2.0	GO:0031648	protein destabilization(GO:0031648)
0.1	0.6	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.1	0.7	GO:0051601	exocyst localization(GO:0051601)
0.1	0.2	GO:1904383	response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.1	0.9	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	0.2	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.1	0.3	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.2	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	1.2	GO:0051014	actin filament severing(GO:0051014)
0.1	1.4	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	0.4	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.1	0.8	GO:0070977	bone maturation(GO:0070977)
0.1	0.2	GO:0035811	negative regulation of urine volume(GO:0035811)
0.1	2.6	GO:0002548	monocyte chemotaxis(GO:0002548)
0.1	0.8	GO:0006449	regulation of translational termination(GO:0006449)
0.1	1.0	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	1.2	GO:0050854	regulation of antigen receptor-mediated signaling pathway(GO:0050854)
0.1	0.2	GO:0043456	regulation of secondary metabolic process(GO:0043455) regulation of pentose-phosphate shunt(GO:0043456)
0.1	1.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.1	GO:0001845	phagolysosome assembly(GO:0001845)
0.1	1.0	GO:0008340	determination of adult lifespan(GO:0008340)
0.1	3.3	GO:0030183	B cell differentiation(GO:0030183)
0.1	0.1	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	0.2	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	0.4	GO:0034378	chylomicron assembly(GO:0034378)
0.1	1.7	GO:0008089	anterograde axonal transport(GO:0008089)
0.1	0.3	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.6	GO:0001502	cartilage condensation(GO:0001502)
0.1	0.3	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.1	0.8	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.1	0.2	GO:0072233	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1	0.5	GO:0051973	regulation of telomerase activity(GO:0051972) positive regulation of telomerase activity(GO:0051973)
0.1	0.2	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1	0.5	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.4	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.6	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	0.3	GO:0048296	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1	0.3	GO:0002084	protein depalmitoylation(GO:0002084) regulation of Golgi to plasma membrane protein transport(GO:0042996) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.2	GO:0005988	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) disaccharide biosynthetic process(GO:0046351)
0.1	0.3	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.1	0.1	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.1	1.7	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	0.3	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.3	GO:1904526	regulation of microtubule binding(GO:1904526)
0.1	1.4	GO:2000785	regulation of autophagosome assembly(GO:2000785)
0.1	0.6	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	2.1	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1	0.9	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.1	0.4	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405)
0.1	0.3	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	0.2	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.1	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.1	2.0	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.1	0.9	GO:0006298	mismatch repair(GO:0006298)
0.1	0.5	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.2	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.0	0.0	GO:1904882	establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0	0.1	GO:0060019	radial glial cell differentiation(GO:0060019)
0.0	0.2	GO:0070829	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0	0.1	GO:0036414	protein citrullination(GO:0018101) citrulline biosynthetic process(GO:0019240) histone citrullination(GO:0036414)
0.0	0.6	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	1.3	GO:0010574	regulation of vascular endothelial growth factor production(GO:0010574)
0.0	0.2	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.0	0.4	GO:0006081	cellular aldehyde metabolic process(GO:0006081)
0.0	0.1	GO:0002902	regulation of B cell apoptotic process(GO:0002902)
0.0	0.4	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.3	GO:0060872	semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.0	0.8	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0051198	negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0	0.8	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.7	GO:1901663	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0	0.4	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.9	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	1.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.3	GO:0031065	positive regulation of histone deacetylation(GO:0031065)
0.0	0.9	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0090520	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.6	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0061436	regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0	0.1	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	1.9	GO:0002223	innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.4	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.3	GO:0006196	AMP catabolic process(GO:0006196)
0.0	0.3	GO:0097194	execution phase of apoptosis(GO:0097194)
0.0	0.1	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.0	0.1	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.2	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.0	0.2	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.7	GO:0018345	protein palmitoylation(GO:0018345)
0.0	2.2	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0	0.1	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.2	GO:0035523	protein K29-linked deubiquitination(GO:0035523) maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.4	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.6	GO:0045116	protein neddylation(GO:0045116)
0.0	0.3	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0071344	diphosphate metabolic process(GO:0071344)
0.0	0.2	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.4	GO:0021915	neural tube development(GO:0021915)
0.0	0.5	GO:0070828	heterochromatin organization(GO:0070828)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.4	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.0	0.8	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.4	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.3	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	1.5	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.2	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.9	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.6	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	1.1	GO:0046949	fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.7	GO:0030218	erythrocyte differentiation(GO:0030218)
0.0	0.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208) dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.3	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.4	GO:0021511	spinal cord patterning(GO:0021511)
0.0	3.4	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.6	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.2	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	1.0	GO:0007140	male meiosis(GO:0007140)
0.0	0.3	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	1.0	GO:0042633	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:1901052	sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0	0.3	GO:0050864	regulation of B cell activation(GO:0050864)
0.0	0.4	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.8	GO:1902749	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0070541	response to platinum ion(GO:0070541)
0.0	1.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.5	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.4	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.3	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.2	GO:0019732	antifungal humoral response(GO:0019732)
0.0	1.8	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.0	GO:0070474	positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.3	GO:0035608	protein deglutamylation(GO:0035608)
0.0	1.1	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.0	0.7	GO:0007616	long-term memory(GO:0007616)
0.0	0.4	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.7	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.2	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.2	GO:0035709	memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0	0.6	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.3	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.4	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	1.3	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	2.0	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.1	GO:1904833	positive regulation of superoxide dismutase activity(GO:1901671) negative regulation of DNA catabolic process(GO:1903625) positive regulation of removal of superoxide radicals(GO:1904833)
0.0	0.1	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0	0.2	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.7	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.3	GO:0010884	positive regulation of lipid storage(GO:0010884)
0.0	0.2	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0	0.3	GO:0014029	neural crest formation(GO:0014029)
0.0	0.1	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct morphogenesis(GO:0072180)
0.0	0.2	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0	0.5	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0	0.3	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.3	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.3	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.4	GO:0032543	mitochondrial translation(GO:0032543)
0.0	4.2	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0042426	choline catabolic process(GO:0042426)
0.0	0.1	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.4	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	1.1	GO:0032945	negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672) negative regulation of leukocyte proliferation(GO:0070664)
0.0	0.1	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.2	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.2	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.3	GO:0021756	striatum development(GO:0021756)
0.0	0.2	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.4	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.5	GO:0031167	rRNA methylation(GO:0031167)
0.0	1.0	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.7	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.5	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.6	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.3	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.5	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.2	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.3	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.4	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.1	GO:0002687	positive regulation of leukocyte migration(GO:0002687)
0.0	0.9	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.7	GO:0003341	cilium movement(GO:0003341)
0.0	0.8	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.3	GO:0030279	negative regulation of ossification(GO:0030279)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	1.0	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.2	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.7	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.1	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0	0.1	GO:0001705	ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.3	GO:0045666	positive regulation of neuron differentiation(GO:0045666)
0.0	0.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.3	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.0	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.4	GO:0006301	postreplication repair(GO:0006301)
0.0	0.1	GO:0033490	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0	0.3	GO:0046839	phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.2	GO:1902358	sulfate transmembrane transport(GO:1902358)
0.0	0.1	GO:0050709	negative regulation of protein secretion(GO:0050709)
0.0	0.3	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.0	0.1	GO:0014004	microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.4	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.1	GO:0042756	drinking behavior(GO:0042756)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0007270	neuron-neuron synaptic transmission(GO:0007270)
0.0	0.0	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.5	GO:0008542	visual learning(GO:0008542)
0.0	0.4	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.7	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0	0.1	GO:0030432	peristalsis(GO:0030432)
0.0	0.3	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.0	0.4	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.1	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.0	0.2	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.2	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.6	GO:0061001	regulation of dendritic spine morphogenesis(GO:0061001)
0.0	0.4	GO:0007050	cell cycle arrest(GO:0007050)
0.0	0.3	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.2	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.2	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.2	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.2	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.3	GO:0042593	carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0	0.3	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.1	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.0	0.2	GO:1901186	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.6	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.3	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0	0.1	GO:0021702	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.0	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0	0.2	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0021871	forebrain regionalization(GO:0021871)
0.0	1.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.2	GO:0097421	liver regeneration(GO:0097421)
0.0	0.4	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	1.1	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.1	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024)
0.0	0.1	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.5	GO:0009301	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.0	0.3	GO:0008344	adult locomotory behavior(GO:0008344)
0.0	0.1	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.0	0.2	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.4	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.0	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.0	0.1	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.1	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.0	GO:0065002	intracellular protein transmembrane transport(GO:0065002)
0.0	0.4	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.1	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.2	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
0.0	0.1	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.0	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	3.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	4.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	2.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	2.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	2.6	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.4	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.7	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	1.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	3.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	9.2	GO:1902560	GMP reductase complex(GO:1902560)
0.7	2.9	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.4	1.8	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.4	1.1	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.2	0.7	GO:0061673	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.2	0.8	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	0.8	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.2	0.8	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	1.3	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	1.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	0.4	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	1.0	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	0.2	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1	0.9	GO:0043186	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1	0.5	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.3	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.1	0.3	GO:0032044	DSIF complex(GO:0032044)
0.1	0.4	GO:0071817	MMXD complex(GO:0071817)
0.1	1.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.4	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.4	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.3	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	0.4	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.2	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.2	GO:0070847	core mediator complex(GO:0070847)
0.0	0.3	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.1	GO:1902636	kinociliary basal body(GO:1902636)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.3	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0055087	Ski complex(GO:0055087)
0.0	0.4	GO:0017119	Golgi transport complex(GO:0017119)
0.0	1.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.3	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.7	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.4	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.2	GO:0097443	sorting endosome(GO:0097443)
0.0	1.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.2	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.5	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.7	GO:0043025	neuronal cell body(GO:0043025)
0.0	0.4	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.3	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.2	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.2	GO:0043203	axon hillock(GO:0043203)
0.0	1.1	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	2.7	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	1.4	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.4	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.0	0.1	GO:0034709	methylosome(GO:0034709)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.8	GO:0043203	axon hillock(GO:0043203)
0.3	1.3	GO:0005726	perichromatin fibrils(GO:0005726)
0.3	1.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	0.6	GO:0005607	laminin-2 complex(GO:0005607)
0.1	1.7	GO:0030478	actin cap(GO:0030478)
0.1	3.5	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	1.1	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.2	GO:0034685	integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.1	1.3	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	1.2	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	2.9	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.1	GO:0005873	plus-end kinesin complex(GO:0005873)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0	2.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	1.0	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.5	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	1.4	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	0.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	1.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	3.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.7	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	2.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.9	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.5	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.7	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	2.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	0.9	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.0	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.2	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	2.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
4.1	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.6	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5	PID AVB3 OPN PATHWAY	Osteopontin-mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.6	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	1.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.6	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.8	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	1.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.8	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	8.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.0	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	4.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.3	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	2.9	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	5.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.8	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	1.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	1.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	8.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4	11.5	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.4	13.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	2.9	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	5.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	4.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	5.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	1.8	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	5.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	4.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.6	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	8.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	12.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.1	0.9	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	7.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	4.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	2.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	2.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	4.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	3.6	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	1.5	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	3.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.5	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	1.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.7	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.8	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	1.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	4.2	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	2.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.7	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	2.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	2.3	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	2.2	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	1.0	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.8	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	1.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	3.3	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	2.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.7	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	1.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.6	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.8	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	5.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	5.8	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.2	3.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	2.5	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	2.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	2.7	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	0.4	REACTOME S PHASE	Genes involved in S Phase
0.1	1.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	3.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	3.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.8	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	0.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	2.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	0.5	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.7	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	2.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	1.8	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	2.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	2.0	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.1	1.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	4.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	5.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	1.0	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	0.3	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	1.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	1.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	1.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	1.0	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	1.0	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	1.8	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	0.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	0.5	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	0.7	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.6	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	0.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.2	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	0.7	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	3.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	0.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	3.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	7.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	0.4	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	0.4	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	2.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.9	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	1.6	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.7	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	1.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	1.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	1.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	2.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.3	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	4.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	1.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.0	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	3.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	1.5	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.1	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	1.1	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.3	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	4.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.2	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.6	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	1.2	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.6	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.6	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME CELL CYCLE CHECKPOINTS	Genes involved in Cell Cycle Checkpoints
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.0	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.8	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.5	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.4	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	1.7	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.6	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.2	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	2.8	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.7	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0	0.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.5	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.7	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0000354	cis assembly of pre-catalytic spliceosome(GO:0000354)
0.4	1.5	GO:0034445	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.3	1.4	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3	1.3	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2	0.6	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.2	0.5	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.2	0.5	GO:0097359	UDP-glucosylation(GO:0097359)
0.2	0.9	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2	1.7	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2	0.8	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.2	0.5	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.1	0.7	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.4	GO:0046833	snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.1	1.7	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.3	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.1	0.3	GO:1902528	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1	1.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.3	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.3	GO:0032053	ciliary basal body organization(GO:0032053)
0.1	0.3	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.1	0.2	GO:0015920	lipopolysaccharide transport(GO:0015920)
0.1	0.3	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.1	1.3	GO:0006020	inositol metabolic process(GO:0006020)
0.1	0.2	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.2	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1	0.2	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.1	0.9	GO:0035878	nail development(GO:0035878)
0.1	0.3	GO:0032416	negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1	0.2	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1	0.2	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	1.3	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.6	GO:0030263	resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	0.2	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.0	0.2	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.2	GO:0044806	G-quadruplex DNA unwinding(GO:0044806) replication fork protection(GO:0048478)
0.0	0.3	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.3	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.0	0.3	GO:0051013	microtubule severing(GO:0051013)
0.0	0.3	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.1	GO:0072334	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0	0.3	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.4	GO:0006983	ER overload response(GO:0006983)
0.0	0.2	GO:0042631	cellular response to water deprivation(GO:0042631)
0.0	0.2	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.2	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.7	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.9	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.5	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.4	GO:0015074	DNA integration(GO:0015074)
0.0	0.4	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.7	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.1	GO:0050720	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759) regulation of progesterone biosynthetic process(GO:2000182)
0.0	1.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.1	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.5	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.3	GO:2000535	regulation of entry of bacterium into host cell(GO:2000535)
0.0	0.3	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.0	0.4	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0	0.4	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0021718	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0	0.1	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.0	0.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.3	GO:0014894	response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.4	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.5	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.8	GO:0045730	respiratory burst(GO:0045730)
0.0	0.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.2	GO:1904415	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.1	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) synaptic transmission involved in micturition(GO:0060084)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.2	GO:0002326	B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) ectopic germ cell programmed cell death(GO:0035234)
0.0	0.3	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.2	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.5	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0032632	response to molecule of fungal origin(GO:0002238) interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.0	0.0	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.2	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.5	GO:0072662	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0	1.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.0	GO:1901355	response to rapamycin(GO:1901355)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.3	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.2	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.0	GO:0015883	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0	0.1	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:0002224	toll-like receptor signaling pathway(GO:0002224)
0.0	0.1	GO:0071569	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) protein ufmylation(GO:0071569)
0.0	0.4	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0071732	cellular response to nitric oxide(GO:0071732)
0.0	0.4	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.1	GO:0042492	gamma-delta T cell differentiation(GO:0042492)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.0	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
1.7	5.1	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.2	3.5	GO:1990764	regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.9	3.8	GO:0016333	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.6	4.6	GO:0031642	negative regulation of myelination(GO:0031642)
0.5	1.4	GO:2000097	chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4	1.8	GO:1900535	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.4	2.6	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3	1.7	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.3	3.4	GO:0022417	protein maturation by protein folding(GO:0022417)
0.3	2.9	GO:0002934	desmosome organization(GO:0002934)
0.3	0.8	GO:1902445	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) positive regulation of apoptotic DNA fragmentation(GO:1902512) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3	1.3	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.3	0.8	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
0.2	1.4	GO:0036337	Fas signaling pathway(GO:0036337)
0.2	0.7	GO:0006423	cysteinyl-tRNA aminoacylation(GO:0006423)
0.2	0.6	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.2	0.8	GO:0002572	pro-T cell differentiation(GO:0002572)
0.2	1.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2	1.4	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2	1.0	GO:2000812	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.2	0.6	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.2	0.5	GO:0046521	sphingoid catabolic process(GO:0046521)
0.2	0.9	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.2	3.4	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.1	4.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.4	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	1.5	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.6	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.1	1.2	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.1	0.5	GO:0030047	actin modification(GO:0030047)
0.1	0.7	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	3.2	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.5	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1	0.7	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	1.7	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.1	0.3	GO:0071344	diphosphate metabolic process(GO:0071344)
0.1	0.8	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1	2.0	GO:0007141	male meiosis I(GO:0007141)
0.1	2.0	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.4	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	1.4	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	0.5	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1	0.2	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.1	0.4	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	0.3	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.1	1.3	GO:0097320	protein localization to endosome(GO:0036010) membrane tubulation(GO:0097320)
0.1	0.3	GO:1901098	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1	6.5	GO:0070268	cornification(GO:0070268)
0.1	0.4	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.8	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.2	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.1	0.4	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.0	3.0	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.1	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0	0.2	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
0.0	0.2	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	1.9	GO:0097435	fibril organization(GO:0097435)
0.0	0.5	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0006272	leading strand elongation(GO:0006272)
0.0	0.6	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0060214	stem cell fate commitment(GO:0048865) endocardium formation(GO:0060214)
0.0	0.3	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.4	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.3	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.2	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:1900113	histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0	0.1	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.0	0.7	GO:0019054	modulation by virus of host process(GO:0019054)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.4	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0043132	NAD transport(GO:0043132)
0.0	0.4	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.7	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.7	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.2	GO:0044126	regulation of growth of symbiont in host(GO:0044126)
0.0	0.4	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0050720	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.6	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.8	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	1.1	GO:0008344	adult locomotory behavior(GO:0008344)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.3	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.8	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	3.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	7.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.6	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	1.9	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	2.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.9	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.9	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	0.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	1.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	1.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	3.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	6.4	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.8	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.9	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	1.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.3	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	3.1	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.5	1.6	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.3	0.9	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.3	2.6	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	1.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.2	0.9	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2	1.7	GO:0004111	creatine kinase activity(GO:0004111)
0.2	0.6	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.2	0.6	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2	0.9	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.2	0.5	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2	0.6	GO:0038025	reelin receptor activity(GO:0038025)
0.1	0.4	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1	0.7	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	2.3	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.6	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	3.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.7	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.1	0.4	GO:0004461	lactose synthase activity(GO:0004461)
0.1	1.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.5	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.3	GO:0005502	11-cis retinal binding(GO:0005502)
0.1	1.5	GO:0070628	proteasome binding(GO:0070628)
0.1	0.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	0.3	GO:0002046	opsin binding(GO:0002046)
0.1	1.1	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	1.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.8	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.6	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.3	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.0	5.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.4	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.3	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.4	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.8	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.3	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.6	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.5	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.3	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.3	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.6	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.7	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976) primary miRNA binding(GO:0070878)
0.0	0.7	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.5	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.5	GO:0005521	lamin binding(GO:0005521)
0.0	2.1	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	1.1	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.8	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.5	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.9	GO:0003777	microtubule motor activity(GO:0003777)
0.0	2.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	4.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	3.4	ST STAT3 PATHWAY	STAT3 Pathway
0.2	4.5	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	6.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	1.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	6.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	2.4	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	7.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	2.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	2.5	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	5.3	PID AURORA B PATHWAY	Aurora B signaling
0.1	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	6.9	PID E2F PATHWAY	E2F transcription factor network
0.1	3.0	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	1.9	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.1	1.9	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	5.0	PID BCR 5PATHWAY	BCR signaling pathway
0.1	0.4	PID BARD1 PATHWAY	BARD1 signaling events
0.1	2.6	PID SHP2 PATHWAY	SHP2 signaling
0.1	1.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	1.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	2.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	1.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.8	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	1.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	2.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.7	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	1.9	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	1.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.6	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.3	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.5	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.2	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	1.5	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.7	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.2	PID ATM PATHWAY	ATM pathway
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	1.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.2	4.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	3.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	7.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.9	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	2.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.9	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	2.9	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.8	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	8.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	3.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.8	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.1	4.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	2.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	2.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	2.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	1.2	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	5.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	1.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	1.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.0	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	1.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	2.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	1.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	1.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	2.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.2	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.8	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.7	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	1.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	5.7	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.5	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.0	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.5	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.3	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.4	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	3.7	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.7	10.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.6	10.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.5	63.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.5	13.3	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.5	12.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	15.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.3	7.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3	8.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	3.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.3	4.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	4.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	8.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	2.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.7	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	2.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	5.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	2.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	6.1	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	7.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	3.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	6.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	2.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	5.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	0.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.6	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.7	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	2.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	4.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	3.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.1	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	1.7	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.2	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1	1.5	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	1.0	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	0.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.7	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.8	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.7	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	1.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	1.1	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.0	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.7	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.7	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	1.0	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	9.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.9	10.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.8	2.5	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.7	3.4	GO:0016403	dimethylargininase activity(GO:0016403)
0.7	0.7	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.7	2.0	GO:0098809	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.6	8.7	GO:0031014	troponin T binding(GO:0031014)
0.6	1.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	2.4	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.6	3.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.5	2.1	GO:0004998	transferrin receptor activity(GO:0004998)
0.5	3.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.4	7.4	GO:0003680	AT DNA binding(GO:0003680)
0.4	13.1	GO:0005212	structural constituent of eye lens(GO:0005212)
0.4	2.9	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.4	1.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.4	1.2	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.4	2.4	GO:0030172	troponin C binding(GO:0030172)
0.4	1.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.4	1.4	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3	1.3	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.3	3.8	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.3	1.9	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.3	1.9	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3	1.8	GO:0052655	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3	0.9	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.3	5.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.3	2.7	GO:0001225	RNA polymerase II transcription coactivator binding(GO:0001225)
0.3	2.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.3	1.4	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.3	2.8	GO:0042731	PH domain binding(GO:0042731)
0.3	2.2	GO:0001849	complement component C1q binding(GO:0001849)
0.3	4.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.3	0.8	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.3	1.6	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3	0.8	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.3	1.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.3	1.6	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.3	1.0	GO:0097001	ceramide binding(GO:0097001)
0.2	0.7	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.2	2.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2	2.2	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	1.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.2	0.7	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
0.2	1.7	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2	0.7	GO:0004603	phenylethanolamine N-methyltransferase activity(GO:0004603)
0.2	0.7	GO:0098770	FBXO family protein binding(GO:0098770)
0.2	0.7	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.2	0.5	GO:0042577	lipid phosphatase activity(GO:0042577)
0.2	2.5	GO:0004568	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.2	1.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2	0.2	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2	0.7	GO:0004779	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2	0.9	GO:0004132	dCMP deaminase activity(GO:0004132)
0.2	0.7	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.2	9.1	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	0.6	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.2	0.9	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2	0.8	GO:0061714	folic acid receptor activity(GO:0061714)
0.2	2.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.2	1.0	GO:0046592	polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2	1.8	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2	1.6	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2	0.4	GO:0043398	HLH domain binding(GO:0043398)
0.2	2.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.2	3.9	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.2	2.9	GO:0032036	myosin heavy chain binding(GO:0032036)
0.2	0.6	GO:0032427	GBD domain binding(GO:0032427)
0.2	1.0	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.2	1.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.2	0.8	GO:0016361	activin receptor activity, type I(GO:0016361)
0.2	2.6	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2	0.7	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2	0.9	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2	0.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.2	1.1	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.2	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	0.7	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2	0.5	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2	1.2	GO:0004457	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.2	1.0	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2	0.5	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2	0.9	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.2	0.9	GO:0070097	delta-catenin binding(GO:0070097)
0.2	0.5	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.2	2.2	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	1.3	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	0.7	GO:0032810	sterol response element binding(GO:0032810)
0.2	0.5	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.2	1.6	GO:0035497	cAMP response element binding(GO:0035497)
0.2	0.6	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2	1.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2	0.8	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2	0.6	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.2	0.5	GO:0032184	SUMO polymer binding(GO:0032184)
0.2	0.9	GO:0043426	MRF binding(GO:0043426)
0.2	0.9	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.2	1.4	GO:0005000	vasopressin receptor activity(GO:0005000)
0.2	1.5	GO:0089720	caspase binding(GO:0089720)
0.1	1.6	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.6	GO:0038047	beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1	0.6	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1	1.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.9	GO:0004882	androgen receptor activity(GO:0004882)
0.1	0.3	GO:0030350	iron-responsive element binding(GO:0030350)
0.1	1.6	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.9	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	3.0	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	1.1	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.7	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1	0.6	GO:0032143	single thymine insertion binding(GO:0032143)
0.1	0.5	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	0.7	GO:0052842	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1	0.8	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.4	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.8	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1	1.5	GO:0000150	recombinase activity(GO:0000150)
0.1	0.5	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	0.4	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.7	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	1.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.4	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	0.6	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	0.9	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	0.5	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1	0.9	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	0.5	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.1	0.6	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.1	0.4	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.6	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	0.2	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	3.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.6	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.1	0.9	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	1.3	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.6	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	0.1	GO:0032551	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1	0.3	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.3	GO:0051538	3 iron, 4 sulfur cluster binding(GO:0051538)
0.1	1.9	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.5	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.9	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1	0.3	GO:0016749	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1	6.5	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	0.8	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.7	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.2	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
0.1	4.5	GO:0070888	E-box binding(GO:0070888)
0.1	0.8	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.6	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	1.0	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	0.4	GO:0004074	biliverdin reductase activity(GO:0004074)
0.1	1.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.4	GO:0016972	flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1	0.3	GO:0015235	cobalamin transporter activity(GO:0015235)
0.1	0.8	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.1	0.4	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.1	2.7	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.3	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.1	1.6	GO:0005522	profilin binding(GO:0005522)
0.1	0.4	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.3	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.1	3.3	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.1	0.4	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.3	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	0.3	GO:0017129	triglyceride binding(GO:0017129)
0.1	0.3	GO:0005046	KDEL sequence binding(GO:0005046)
0.1	1.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	5.1	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	0.5	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.6	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.1	1.4	GO:0031005	filamin binding(GO:0031005)
0.1	0.3	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.3	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1	0.3	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	1.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.5	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	0.2	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1	2.0	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	1.6	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.1	0.6	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	1.0	GO:0097100	supercoiled DNA binding(GO:0097100)
0.1	0.4	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	0.3	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	1.7	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.2	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.1	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.1	0.3	GO:0035197	siRNA binding(GO:0035197)
0.1	0.2	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	0.9	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.9	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.1	0.5	GO:0030911	TPR domain binding(GO:0030911)
0.1	0.3	GO:0019770	IgG receptor activity(GO:0019770)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.4	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1	0.2	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	0.1	GO:0035276	ethanol binding(GO:0035276)
0.1	0.3	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.4	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.1	0.8	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.1	3.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1	0.2	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.1	0.3	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.1	0.3	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.1	0.3	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.4	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	1.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.5	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.2	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.6	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.1	7.7	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	0.3	GO:0051373	FATZ binding(GO:0051373)
0.1	0.1	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1	0.1	GO:0044388	small protein activating enzyme binding(GO:0044388)
0.1	0.2	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.1	0.3	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	1.8	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.1	0.5	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	1.8	GO:0031489	myosin V binding(GO:0031489)
0.1	2.0	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.8	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	1.0	GO:0030553	cGMP binding(GO:0030553)
0.1	0.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.2	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.8	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.2	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1	3.7	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	0.2	GO:0036033	mediator complex binding(GO:0036033)
0.1	5.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	2.6	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	0.9	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	1.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	0.2	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.3	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	2.3	GO:0070063	RNA polymerase binding(GO:0070063)
0.1	0.9	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	0.4	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.1	0.8	GO:0031386	protein tag(GO:0031386)
0.1	0.3	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.1	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1	1.8	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	0.4	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	1.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.5	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	0.5	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1	1.0	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.1	0.9	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.3	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.1	0.2	GO:0031716	calcitonin receptor binding(GO:0031716)
0.1	0.3	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1	0.2	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.8	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.8	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	1.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	1.9	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.2	GO:0003953	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.1	6.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.4	GO:1990239	steroid hormone binding(GO:1990239)
0.1	0.3	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.3	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	0.2	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1	0.2	GO:0015616	DNA translocase activity(GO:0015616)
0.1	0.1	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1	0.2	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.1	0.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	0.6	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.7	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1	2.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.2	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.1	0.3	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	0.2	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	0.5	GO:0051920	peroxiredoxin activity(GO:0051920)
0.1	0.6	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.5	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	2.4	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.6	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.7	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.1	0.2	GO:0070051	fibrinogen binding(GO:0070051)
0.1	2.5	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	0.4	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.3	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.3	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	0.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.5	GO:0001671	ATPase activator activity(GO:0001671)
0.1	0.3	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	1.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	1.0	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.1	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.1	6.0	GO:0005262	calcium channel activity(GO:0005262)
0.1	0.3	GO:0008430	selenium binding(GO:0008430)
0.1	0.3	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	1.0	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.3	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0	1.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.4	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.3	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.3	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	1.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.3	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.6	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.7	GO:0016918	retinal binding(GO:0016918)
0.0	0.2	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.4	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0000035	acyl binding(GO:0000035)
0.0	0.8	GO:0043295	glutathione binding(GO:0043295)
0.0	0.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	1.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.3	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	1.5	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.0	0.1	GO:0004819	glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0	0.3	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.7	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.0	0.5	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.2	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0	1.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.3	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.4	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.5	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.2	GO:0047708	biotinidase activity(GO:0047708)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.4	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	0.2	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0004324	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0	0.7	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.4	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.5	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.3	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	0.1	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0	0.7	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.2	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.3	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.6	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.7	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	4.1	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.1	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.6	GO:0005521	lamin binding(GO:0005521)
0.0	0.2	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.3	GO:0004954	prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0	0.2	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	0.0	GO:0035473	lipase binding(GO:0035473)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	2.0	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.3	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:1990763	arrestin family protein binding(GO:1990763)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.3	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	1.3	GO:0004402	histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.3	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.5	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0070905	serine binding(GO:0070905)
0.0	0.5	GO:0070513	death domain binding(GO:0070513)
0.0	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.2	GO:0043532	angiostatin binding(GO:0043532)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.2	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.7	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.4	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.7	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.1	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.9	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0042610	CD8 receptor binding(GO:0042610)
0.0	0.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.0	0.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.0	1.4	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.1	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.2	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.0	0.5	GO:0008266	poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	0.1	GO:0008410	CoA-transferase activity(GO:0008410)
0.0	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0033149	FFAT motif binding(GO:0033149)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.3	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.7	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.3	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0	0.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.7	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.1	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.2	GO:0005497	androgen binding(GO:0005497)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	1.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.7	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	3.7	GO:0008201	heparin binding(GO:0008201)
0.0	0.2	GO:0030249	cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0	0.5	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0	0.1	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	1.2	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.7	GO:0035326	enhancer binding(GO:0035326)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.0	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0	0.1	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.5	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.4	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0031208	POZ domain binding(GO:0031208)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.2	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.3	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.8	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.2	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	1.0	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.8	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.0	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.6	GO:0034062	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.4	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.3	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.0	0.1	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	0.0	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.0	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.4	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.1	GO:0043022	ribosome binding(GO:0043022)
0.0	0.5	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	0.3	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.0	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	2.6	GO:0015631	tubulin binding(GO:0015631)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0	0.3	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.0	GO:0004766	spermidine synthase activity(GO:0004766)
0.0	0.2	GO:0008483	transaminase activity(GO:0008483)
0.0	0.0	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0005048	signal sequence binding(GO:0005048)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	3.5	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	2.6	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.8	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	1.5	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.2	4.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	3.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	4.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	3.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	8.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	4.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.3	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	3.9	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	4.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	3.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	3.9	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	2.9	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	0.3	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	1.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	3.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	0.3	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.1	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	4.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	3.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	1.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	2.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	2.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	5.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.8	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.7	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	1.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	1.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.4	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.1	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.6	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	1.0	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.8	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	1.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	1.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	1.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.7	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.4	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.8	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	1.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.7	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	3.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.9	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.2	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	0.7	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.6	GO:0016012	sarcoglycan complex(GO:0016012)
0.3	1.3	GO:0043259	laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.2	0.8	GO:0031166	integral component of vacuolar membrane(GO:0031166)
0.2	0.5	GO:0005588	collagen type V trimer(GO:0005588)
0.2	2.0	GO:0033010	paranodal junction(GO:0033010)
0.2	0.8	GO:0097513	myosin II filament(GO:0097513)
0.1	0.6	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.1	1.3	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.8	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	1.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	2.4	GO:0097546	ciliary base(GO:0097546)
0.1	1.2	GO:0042599	lamellar body(GO:0042599)
0.1	0.2	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	2.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.9	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.5	GO:0097227	sperm annulus(GO:0097227)
0.0	0.5	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.5	GO:0044295	axonal growth cone(GO:0044295)
0.0	3.9	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0031310	intrinsic component of vacuolar membrane(GO:0031310)
0.0	2.0	GO:0005882	intermediate filament(GO:0005882)
0.0	0.4	GO:0031045	dense core granule(GO:0031045)
0.0	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	3.2	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.0	GO:0097679	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.0	0.2	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.9	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	10.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	2.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	3.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	6.4	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	2.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	0.6	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.1	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	4.7	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	1.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	1.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	3.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	1.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	1.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	4.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	3.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	3.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.6	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.0	112.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
3.4	50.5	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
1.8	25.5	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
1.4	34.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.2	26.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
1.2	26.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.9	16.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.5	9.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4	14.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.4	8.8	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.3	5.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.3	5.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.3	5.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	12.3	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.2	9.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.2	3.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2	20.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	3.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	12.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	2.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	3.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	12.4	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.1	0.8	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	1.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.8	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	7.6	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.3	7.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	1.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	2.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	2.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	3.4	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	0.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	2.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.1	3.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	0.5	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	1.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.8	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.1	3.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	1.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.8	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.9	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.7	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	2.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.8	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.9	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	1.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	2.0	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.6	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	1.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.7	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.0	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.0	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.8	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	1.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.8	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	1.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.8	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	2.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.6	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	2.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0070939	Dsl1p complex(GO:0070939)
0.1	1.4	GO:0097255	R2TP complex(GO:0097255)
0.1	0.9	GO:0031298	replication fork protection complex(GO:0031298)
0.1	0.4	GO:0070876	SOSS complex(GO:0070876)
0.1	0.7	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	0.6	GO:0031931	TORC1 complex(GO:0031931)
0.1	1.0	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.7	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.1	0.6	GO:0032039	integrator complex(GO:0032039)
0.1	0.7	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	0.5	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1	0.2	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.1	1.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.2	GO:0016938	kinesin I complex(GO:0016938)
0.1	0.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.0	0.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.4	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:0030689	Noc complex(GO:0030689)
0.0	1.3	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.2	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.5	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.6	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	1.5	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	2.0	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.2	GO:1990037	Lewy body core(GO:1990037)
0.0	0.3	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.2	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.4	GO:0036038	MKS complex(GO:0036038)
0.0	0.2	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.2	GO:0061617	MICOS complex(GO:0061617)
0.0	0.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.2	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:0032433	filopodium tip(GO:0032433)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:1990075	periciliary membrane compartment(GO:1990075)
0.0	1.3	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.3	GO:0097433	dense body(GO:0097433)
0.0	0.7	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.1	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.0	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.0	GO:0034455	t-UTP complex(GO:0034455)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.4	GO:0043005	neuron projection(GO:0043005)
0.0	0.2	GO:0090543	Flemming body(GO:0090543)
0.0	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0098845	postsynaptic endosome(GO:0098845)
0.0	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0	1.2	GO:0000779	condensed chromosome, centromeric region(GO:0000779)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	3.0	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	3.1	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.5	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.1	0.9	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	2.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	4.7	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	3.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	1.9	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	2.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.8	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	2.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	3.6	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	3.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.9	ST STAT3 PATHWAY	STAT3 Pathway
0.2	4.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.2	8.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	6.5	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	0.9	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	5.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	0.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	2.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	6.4	PID LKB1 PATHWAY	LKB1 signaling events
0.1	5.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	0.9	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	3.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.3	PID MYC PATHWAY	C-MYC pathway
0.1	4.4	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	3.7	PID NOTCH PATHWAY	Notch signaling pathway
0.1	2.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	2.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	1.9	PID REELIN PATHWAY	Reelin signaling pathway
0.1	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	0.6	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	4.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	1.8	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.8	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	2.1	PID ATR PATHWAY	ATR signaling pathway
0.0	3.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	2.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	2.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	4.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.7	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.6	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	1.7	PID E2F PATHWAY	E2F transcription factor network
0.0	0.8	PID ATM PATHWAY	ATM pathway
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.5	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.5	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.5	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.6	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.3	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.0	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	4.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	1.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.8	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	1.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
3.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.8	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
2.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.7	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.9	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.5	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.5	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
1.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
1.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.6	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.3	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	0.4	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	1.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.7	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.4	GO:1990037	Lewy body core(GO:1990037)
0.1	0.3	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	0.4	GO:0061617	MICOS complex(GO:0061617)
0.0	2.4	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	0.2	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	1.0	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.5	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0	0.6	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.0	1.1	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.7	GO:0071564	npBAF complex(GO:0071564)
0.0	0.2	GO:0070938	contractile ring(GO:0070938)
0.0	0.2	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.1	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	3.1	GO:0035579	specific granule membrane(GO:0035579)
0.0	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	0.8	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.4	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	1.1	GO:0031672	A band(GO:0031672)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.4	GO:0005861	troponin complex(GO:0005861)
0.0	1.1	GO:0009986	cell surface(GO:0009986)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.5	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.1	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.0	0.3	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.9	GO:0061689	tricellular tight junction(GO:0061689)
0.3	0.9	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.3	3.6	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.2	1.1	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.2	0.8	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.2	2.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.2	0.8	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.2	1.0	GO:1902560	GMP reductase complex(GO:1902560)
0.1	0.4	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1	1.0	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	0.8	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.5	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1	0.4	GO:0018444	translation release factor complex(GO:0018444)
0.1	1.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	0.5	GO:1990393	3M complex(GO:1990393)
0.1	0.4	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.8	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	0.5	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	2.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	0.6	GO:0019815	B cell receptor complex(GO:0019815)
0.1	0.9	GO:0043203	axon hillock(GO:0043203)
0.1	0.6	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.3	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	0.3	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1	0.2	GO:0032044	DSIF complex(GO:0032044)
0.1	1.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	0.9	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.1	1.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.2	GO:0071020	post-spliceosomal complex(GO:0071020)
0.0	0.8	GO:0097342	ripoptosome(GO:0097342)
0.0	0.3	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	0.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.2	GO:0001940	male pronucleus(GO:0001940)
0.0	0.3	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.5	GO:0042555	MCM complex(GO:0042555)
0.0	1.8	GO:0045095	keratin filament(GO:0045095)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.7	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.8	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.5	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	1.1	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.2	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.3	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.6	GO:0030686	90S preribosome(GO:0030686)
0.0	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.6	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0005884	actin filament(GO:0005884)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.4	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.2	GO:0097025	lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.3	GO:0043194	axon initial segment(GO:0043194)
0.0	1.7	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.5	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0031906	late endosome lumen(GO:0031906)
0.0	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.4	GO:0031105	septin complex(GO:0031105)
0.0	0.5	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0031209	SCAR complex(GO:0031209)
0.0	0.6	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.5	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	1.1	GO:0005811	lipid particle(GO:0005811)
0.0	0.9	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.0	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.0	0.3	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.0	GO:0071159	NF-kappaB complex(GO:0071159)
0.0	1.5	GO:0001650	fibrillar center(GO:0001650)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	2.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.8	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0	3.8	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.8	2.5	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.8	3.0	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.6	1.7	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5	1.5	GO:0031587	detection of endogenous stimulus(GO:0009726) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.5	1.9	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5	0.9	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.5	1.4	GO:0031049	mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.5	5.5	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.5	3.2	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4	1.3	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.4	2.0	GO:0072312	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.4	1.2	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4	1.9	GO:0097338	response to clozapine(GO:0097338)
0.4	1.1	GO:0006711	estrogen catabolic process(GO:0006711)
0.4	3.6	GO:0070141	response to UV-A(GO:0070141)
0.3	1.0	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3	2.0	GO:0090131	mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.3	1.3	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.3	1.0	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.3	1.3	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3	1.9	GO:1902847	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3	0.6	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.3	2.8	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3	2.1	GO:0001845	phagolysosome assembly(GO:0001845) negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3	1.3	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.2	0.5	GO:2000683	regulation of cellular response to X-ray(GO:2000683)
0.2	0.7	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2	1.9	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	0.7	GO:0052331	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2	2.6	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.2	0.6	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2	0.6	GO:0032474	otolith morphogenesis(GO:0032474)
0.2	0.6	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.2	2.5	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2	0.6	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.2	0.7	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.2	0.7	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.2	1.0	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.2	0.8	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.2	1.7	GO:0034465	response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.2	1.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.6	GO:0060434	bronchus morphogenesis(GO:0060434)
0.1	0.6	GO:0019087	transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.1	0.4	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1	0.9	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	1.3	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.4	GO:1903487	regulation of lactation(GO:1903487)
0.1	0.5	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.1	0.5	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.1	0.1	GO:0051081	mitotic nuclear envelope disassembly(GO:0007077) membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1	0.3	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.1	4.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.3	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1	0.6	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.8	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.8	GO:0006013	mannose metabolic process(GO:0006013)
0.1	0.2	GO:0048611	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1	0.8	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.6	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	2.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	1.8	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.4	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.6	GO:0051012	microtubule sliding(GO:0051012)
0.1	0.4	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.1	0.4	GO:2001202	negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.1	0.4	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1	1.2	GO:0014831	gastro-intestinal system smooth muscle contraction(GO:0014831)
0.1	0.3	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.4	GO:2000035	regulation of stem cell division(GO:2000035)
0.1	0.2	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	0.2	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	0.4	GO:0016476	regulation of embryonic cell shape(GO:0016476)
0.1	1.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	1.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.9	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.2	GO:0021558	trochlear nerve development(GO:0021558)
0.1	0.8	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.2	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1	0.2	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.1	0.3	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	0.2	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.3	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.1	2.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.6	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.2	GO:2000317	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1	0.6	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.2	GO:0090260	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1	0.2	GO:0001983	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1	1.0	GO:0032060	bleb assembly(GO:0032060)
0.1	0.2	GO:0060151	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1	0.1	GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0	0.6	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	0.1	GO:0034382	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	1.1	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.6	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.3	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	0.1	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0	1.0	GO:0007567	parturition(GO:0007567)
0.0	0.2	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.0	0.2	GO:0015811	L-cystine transport(GO:0015811)
0.0	0.4	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.3	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.7	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.4	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.0	1.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.2	GO:0060179	male mating behavior(GO:0060179)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.3	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.7	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	1.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:1904435	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0	0.9	GO:1902624	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.2	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.0	0.4	GO:0051601	exocyst localization(GO:0051601)
0.0	0.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.5	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.7	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.2	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0034959	substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0	0.9	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	2.2	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.5	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.7	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.0	0.7	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.2	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.2	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.9	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.9	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.3	GO:0061339	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.3	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0	0.2	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.7	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.1	GO:1904888	cranial skeletal system development(GO:1904888)
0.0	0.5	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	0.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	2.4	GO:0043647	inositol phosphate metabolic process(GO:0043647)
0.0	0.3	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	1.0	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.2	GO:0061025	membrane fusion(GO:0061025)
0.0	1.0	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.7	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0	0.2	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	1.2	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.4	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.2	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	1.8	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.6	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.0	0.2	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.9	GO:0006739	NADP metabolic process(GO:0006739)
0.0	0.1	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.7	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.3	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.0	0.6	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0006705	mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.2	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:1990440	ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.4	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	3.5	GO:0007160	cell-matrix adhesion(GO:0007160)
0.0	0.1	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.2	GO:0001780	neutrophil homeostasis(GO:0001780)
0.0	0.4	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.3	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.9	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.6	GO:1901998	toxin transport(GO:1901998)
0.0	0.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	5.7	GO:0019216	regulation of lipid metabolic process(GO:0019216)
0.0	0.1	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.2	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.6	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.7	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.2	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0051384	response to glucocorticoid(GO:0051384)
0.0	1.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0044026	DNA hypermethylation(GO:0044026)
0.0	0.0	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0030307	positive regulation of cell growth(GO:0030307)
0.0	0.0	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.1	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0	0.1	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.1	GO:0044241	lipid digestion(GO:0044241)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.7	GO:0050700	CARD domain binding(GO:0050700)
0.1	3.3	GO:0031489	myosin V binding(GO:0031489)
0.1	1.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	1.2	GO:0008199	ferric iron binding(GO:0008199)
0.1	0.3	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1	0.3	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.7	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	0.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	1.5	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.6	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.2	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.0	1.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.6	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.7	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.6	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.3	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	2.3	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	3.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.2	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	1.8	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.3	GO:0015250	water channel activity(GO:0015250)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	1.2	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.5	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	12.7	GO:0071748	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.4	2.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.3	1.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2	4.3	GO:0001891	phagocytic cup(GO:0001891)
0.2	0.8	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	9.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	0.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	0.7	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	1.2	GO:0070578	RISC-loading complex(GO:0070578)
0.1	0.7	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.4	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.7	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.3	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1	0.9	GO:0035631	CD40 receptor complex(GO:0035631)
0.1	0.4	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.2	GO:0005879	axonemal microtubule(GO:0005879)
0.1	1.8	GO:0035371	microtubule plus-end(GO:0035371)
0.1	1.0	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.5	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	1.4	GO:0071437	invadopodium(GO:0071437)
0.0	1.0	GO:0031519	PcG protein complex(GO:0031519)
0.0	1.7	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	1.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.7	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.7	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.6	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.5	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.4	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.2	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.3	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	1.1	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	1.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.8	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	4.3	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.3	GO:0045095	keratin filament(GO:0045095)
0.0	1.2	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	3.9	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.2	GO:0097255	R2TP complex(GO:0097255)
0.0	2.2	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	1.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0042629	mast cell granule(GO:0042629)
0.0	0.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	1.1	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	2.2	GO:0072562	blood microparticle(GO:0072562)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.4	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.3	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	8.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.4	23.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.4	8.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	6.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.3	4.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	1.8	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	5.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	5.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	5.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.2	24.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	4.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	3.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	3.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	5.2	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	7.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	2.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	4.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.3	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.9	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.8	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.5	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.0	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	1.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	40.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
1.5	33.6	REACTOME LAGGING STRAND SYNTHESIS	Genes involved in Lagging Strand Synthesis
1.0	19.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.7	0.7	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.7	10.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.6	11.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.5	6.8	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.4	18.5	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	2.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.3	12.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3	6.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.3	5.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	1.5	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.3	7.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.2	4.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	2.6	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2	3.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	7.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	0.7	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	6.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.2	6.0	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	4.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	3.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2	3.7	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.2	0.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2	18.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	1.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	2.7	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.2	4.8	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	2.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.6	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	3.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	1.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	3.5	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	3.8	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	0.3	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	2.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	2.1	REACTOME MEIOSIS	Genes involved in Meiosis
0.1	2.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	3.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	1.7	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	1.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	9.0	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.1	3.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	2.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	1.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.8	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	0.2	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.1	0.7	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	1.5	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1	1.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	0.9	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	1.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	2.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.1	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.1	1.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	1.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.2	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.1	1.0	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	1.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	1.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	2.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	5.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	0.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	1.6	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	4.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	1.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	5.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.8	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	2.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.4	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.7	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.7	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	2.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	3.0	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0	1.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	1.1	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	1.1	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	1.6	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	2.0	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	1.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	3.5	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	5.0	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.4	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.4	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.4	REACTOME PURINE METABOLISM	Genes involved in Purine metabolism
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.4	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels

Gene overrepresentation in C2:CP category:

Total log-likelihood	Term	Description
1.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.6	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
1.2	PID TNF PATHWAY	TNF receptor signaling pathway
1.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.9	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	1.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	1.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.5	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.6	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.7	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	0.1	REACTOME GABA B RECEPTOR ACTIVATION	Genes involved in GABA B receptor activation
0.1	0.3	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	1.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	0.9	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	1.0	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1	2.9	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	0.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.6	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.1	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.1	1.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	0.9	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	1.8	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	0.7	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	1.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	0.5	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	0.7	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	1.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	0.8	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	1.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.3	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.7	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	1.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	1.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.8	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.8	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	1.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.7	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	1.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	1.0	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.3	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.6	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.6	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	1.8	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	3.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	1.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.6	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	2.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	1.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.3	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.3	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	1.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.3	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.4	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.3	REACTOME SEMAPHORIN INTERACTIONS	Genes involved in Semaphorin interactions
0.0	0.6	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.0	REACTOME TRIF MEDIATED TLR3 SIGNALING	Genes involved in TRIF mediated TLR3 signaling
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.5	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.1	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.5	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.4	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.5	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.0	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.7	REACTOME ACTIVATED TLR4 SIGNALLING	Genes involved in Activated TLR4 signalling
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	0.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	5.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	5.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	3.6	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.6	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	0.7	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	0.4	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	5.9	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	2.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.8	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	2.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	2.4	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	3.5	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.7	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.6	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.4	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.7	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.3	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.3	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.4	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.8	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.4	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.4	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.3	3.9	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.3	0.8	GO:0009996	negative regulation of cell fate specification(GO:0009996)
0.2	1.3	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	0.3	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.2	GO:0009447	putrescine catabolic process(GO:0009447)
0.1	0.2	GO:1904617	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1	0.6	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.5	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.1	GO:2000395	ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0	0.3	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0072678	T cell migration(GO:0072678)
0.0	1.1	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.2	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.4	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.3	3.3	GO:0005577	fibrinogen complex(GO:0005577)
0.2	1.5	GO:1990584	cardiac Troponin complex(GO:1990584)
0.2	1.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	1.6	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2	4.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2	2.9	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.5	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2	0.8	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	1.3	GO:0016342	catenin complex(GO:0016342)
0.1	1.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.6	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.6	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	2.7	GO:0005859	muscle myosin complex(GO:0005859)
0.1	0.6	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.4	GO:1990761	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0	0.3	GO:0035976	AP1 complex(GO:0035976)
0.0	5.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.3	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.3	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	2.4	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.0	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	1.0	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.6	GO:0005771	multivesicular body(GO:0005771)
0.0	17.1	GO:0005615	extracellular space(GO:0005615)
0.0	1.6	GO:0030018	Z disc(GO:0030018)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	6.3	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5	1.6	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.4	1.1	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.3	1.7	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3	3.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.3	3.2	GO:0042301	phosphate ion binding(GO:0042301)
0.2	0.6	GO:1904288	BAT3 complex binding(GO:1904288)
0.2	4.0	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2	0.8	GO:0004359	glutaminase activity(GO:0004359)
0.2	1.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2	1.3	GO:0001849	complement component C1q binding(GO:0001849)
0.1	1.3	GO:0043426	MRF binding(GO:0043426)
0.1	0.7	GO:0001515	opioid peptide activity(GO:0001515)
0.1	1.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.4	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	0.5	GO:0097643	amylin receptor activity(GO:0097643)
0.1	0.4	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.0	1.2	GO:0017166	vinculin binding(GO:0017166)
0.0	1.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	1.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	1.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.8	GO:0050811	GABA receptor binding(GO:0050811)
0.0	6.6	GO:0044325	ion channel binding(GO:0044325)
0.0	1.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0048763	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0	0.4	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.2	GO:0046979	TAP2 binding(GO:0046979)
0.0	2.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.4	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	1.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.3	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.7	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.7	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	4.3	GO:0019238	cyclohydrolase activity(GO:0019238)
0.6	4.8	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.5	1.4	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.4	2.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.4	1.2	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.4	21.7	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.3	0.8	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.2	1.7	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.2	0.8	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2	1.9	GO:0019237	centromeric DNA binding(GO:0019237)
0.2	1.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.2	1.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2	30.0	GO:0003823	antigen binding(GO:0003823)
0.1	1.6	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	3.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.7	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	1.2	GO:0070883	pre-miRNA binding(GO:0070883)
0.1	0.4	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1	0.3	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	1.2	GO:0031852	mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1	0.5	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.6	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	1.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.8	GO:0000150	recombinase activity(GO:0000150)
0.1	0.3	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.1	0.4	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.9	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.1	0.5	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800) selenium binding(GO:0008430)
0.1	0.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	1.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.7	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.3	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.0	0.5	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0	0.4	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.3	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	1.1	GO:0071949	FAD binding(GO:0071949)
0.0	0.5	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	6.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.2	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.0	1.0	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.3	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.3	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.0	0.2	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	5.0	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.7	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.3	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.9	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	1.4	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.5	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.1	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.0	1.1	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.4	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	1.0	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	27.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	4.7	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	5.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	4.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	2.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	4.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	3.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.8	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	11.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.7	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	1.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	2.0	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	8.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.5	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	3.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.2	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.5	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.3	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.6	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.5	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.8	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.7	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.5	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.9	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	10.4	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
3.0	11.9	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.4	12.4	GO:0030450	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
1.0	3.1	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.0	4.9	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.7	2.2	GO:1904647	response to rotenone(GO:1904647)
0.6	1.9	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.6	1.8	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.5	1.9	GO:0021564	vagus nerve development(GO:0021564)
0.4	2.4	GO:1902847	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4	5.8	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3	3.0	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.3	2.0	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3	2.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.2	0.7	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2	1.2	GO:0060356	leucine import(GO:0060356)
0.2	1.0	GO:1902896	terminal web assembly(GO:1902896)
0.2	1.6	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.2	0.5	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	1.6	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.1	0.9	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	2.6	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	3.8	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.8	GO:0070417	cellular response to cold(GO:0070417) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.3	GO:0035993	subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1	0.4	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1	0.4	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.1	1.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.3	GO:0010585	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1	0.5	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.1	0.3	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.1	0.4	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.1	1.2	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.3	GO:2000973	midbrain morphogenesis(GO:1904693) regulation of pro-B cell differentiation(GO:2000973)
0.1	0.4	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	1.3	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	1.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.5	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0	0.5	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	2.3	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	1.7	GO:0031648	protein destabilization(GO:0031648)
0.0	0.9	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.8	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.5	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	1.0	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.7	GO:0016577	histone demethylation(GO:0016577)
0.0	0.3	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.9	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:0090118	receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.0	GO:0047115	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.3	0.8	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1	0.4	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.9	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	1.3	GO:0030280	structural constituent of epidermis(GO:0030280)
0.1	0.3	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.0	0.4	GO:0032190	acrosin binding(GO:0032190)
0.0	0.8	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	1.1	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.1	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.3	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0016015	morphogen activity(GO:0016015)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.5	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	3.4	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	0.7	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	2.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	4.5	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	2.8	PID BMP PATHWAY	BMP receptor signaling
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	4.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.6	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	2.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	1.0	PID IFNG PATHWAY	IFN-gamma pathway
0.0	2.9	PID FGF PATHWAY	FGF signaling pathway
0.0	0.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	1.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.6	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	3.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.7	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.4	8.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	6.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	7.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	19.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	2.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	1.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	1.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	2.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	5.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	2.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	2.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	2.6	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	1.3	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	2.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	1.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	1.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	12.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	3.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	1.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	2.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	1.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	4.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.3	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	2.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	1.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	2.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	0.9	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1	1.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	0.9	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	1.0	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.6	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	4.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	0.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	3.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	2.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	1.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.6	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	4.7	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	3.3	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.0	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.4	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.6	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.9	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	3.8	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.0	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.0	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	1.1	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.8	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	1.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	1.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.6	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	1.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.1	GO:0034711	inhibin binding(GO:0034711)
0.2	1.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.4	GO:0005174	CD40 receptor binding(GO:0005174)
0.1	0.4	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.7	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	1.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	1.4	GO:0038132	neuregulin binding(GO:0038132)
0.1	1.3	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	1.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0032093	SAM domain binding(GO:0032093)
0.1	0.7	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	2.7	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.1	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.0	0.9	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0051870	methotrexate binding(GO:0051870)
0.0	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.5	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	1.1	GO:0005080	protein kinase C binding(GO:0005080)
0.0	1.0	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.6	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	1.4	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.9	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.0	0.4	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0001093	TFIIB-class transcription factor binding(GO:0001093)
0.0	0.2	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	6.9	GO:0003682	chromatin binding(GO:0003682)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	2.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	2.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	2.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	7.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.9	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	4.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	3.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.7	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.0	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	0.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	2.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	8.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	1.1	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	1.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.9	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	2.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	3.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.5	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	3.5	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.6	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.8	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	0.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	3.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.6	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.6	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.6	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.5	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.4	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	2.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	3.6	PID IGF1 PATHWAY	IGF1 pathway
0.1	3.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	1.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	4.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	2.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.5	PID INSULIN PATHWAY	Insulin Pathway
0.0	1.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	1.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	1.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.4	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.7	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.6	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.2	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	3.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	2.1	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.5	3.4	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.5	5.3	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4	4.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4	0.9	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4	1.3	GO:0004603	phenylethanolamine N-methyltransferase activity(GO:0004603)
0.4	1.7	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.4	2.1	GO:0000298	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.4	2.0	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.4	1.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.4	1.5	GO:0032143	single thymine insertion binding(GO:0032143)
0.3	1.4	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3	2.0	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.3	0.9	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3	1.5	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.3	0.3	GO:0030955	potassium ion binding(GO:0030955)
0.3	2.0	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3	1.7	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.3	1.6	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.3	0.8	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	3.4	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.2	0.7	GO:1904288	BAT3 complex binding(GO:1904288)
0.2	0.7	GO:0070364	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.2	1.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2	0.7	GO:0033149	FFAT motif binding(GO:0033149)
0.2	1.5	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2	0.6	GO:0004103	choline kinase activity(GO:0004103)
0.2	0.8	GO:0035939	microsatellite binding(GO:0035939)
0.2	2.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.2	2.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.2	0.8	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.2	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.2	0.6	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2	0.6	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.2	0.6	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.2	1.9	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.2	2.0	GO:0034056	estrogen response element binding(GO:0034056)
0.2	0.5	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2	0.5	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
0.2	1.0	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2	1.4	GO:0097322	7SK snRNA binding(GO:0097322)
0.2	0.8	GO:0061665	SUMO ligase activity(GO:0061665)
0.2	1.0	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.2	0.8	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.2	0.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	0.7	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.2	1.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	2.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	2.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2	1.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	0.4	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	3.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.4	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.4	GO:0097158	pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1	0.6	GO:0038025	reelin receptor activity(GO:0038025)
0.1	2.0	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.6	GO:0004594	pantothenate kinase activity(GO:0004594)
0.1	0.4	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.1	0.4	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.1	0.9	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.1	0.4	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.4	GO:0015039	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1	0.5	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	1.8	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.5	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
0.1	1.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.4	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	2.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	3.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.6	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.1	0.5	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.8	GO:0030620	U2 snRNA binding(GO:0030620)
0.1	0.8	GO:0017002	activin-activated receptor activity(GO:0017002)
0.1	0.5	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1	1.3	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.6	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	1.8	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.4	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.1	0.3	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1	0.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	1.2	GO:0035197	siRNA binding(GO:0035197)
0.1	0.6	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.4	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.4	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	0.3	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	4.2	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.3	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	1.0	GO:0043014	alpha-tubulin binding(GO:0043014)
0.1	1.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.4	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.3	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	1.6	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.2	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.1	0.5	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.4	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	1.9	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.1	2.9	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	0.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.1	1.4	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	0.9	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.2	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1	0.1	GO:0004672	protein kinase activity(GO:0004672)
0.1	1.8	GO:0004659	prenyltransferase activity(GO:0004659)
0.1	0.5	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.1	1.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	1.0	GO:0015926	glucosidase activity(GO:0015926)
0.1	0.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.3	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
0.1	0.6	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.2	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	1.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	0.2	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1	0.5	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.5	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.1	0.5	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.1	0.2	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1	2.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	4.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	0.4	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.1	0.7	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.4	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.6	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	2.7	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.4	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	5.9	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	0.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.3	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	1.8	GO:0005521	lamin binding(GO:0005521)
0.1	1.5	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	0.2	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.1	0.3	GO:0003696	satellite DNA binding(GO:0003696)
0.1	0.7	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	0.6	GO:1901612	cardiolipin binding(GO:1901612)
0.1	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.5	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.3	GO:0097100	supercoiled DNA binding(GO:0097100)
0.1	0.7	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	1.6	GO:0070034	telomerase RNA binding(GO:0070034)
0.1	0.7	GO:0031386	protein tag(GO:0031386)
0.1	0.2	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	0.3	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.7	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.3	GO:0030957	Tat protein binding(GO:0030957)
0.1	1.0	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	0.9	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	2.4	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	1.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.2	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	1.8	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	2.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	0.6	GO:0035198	miRNA binding(GO:0035198)
0.1	0.7	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	0.8	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1	0.2	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.4	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.1	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.1	0.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.2	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.1	0.2	GO:0004137	deoxycytidine kinase activity(GO:0004137)
0.1	0.6	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	1.7	GO:0016896	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.1	0.9	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.5	GO:0035173	histone kinase activity(GO:0035173)
0.1	0.5	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.6	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.6	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.9	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	1.2	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	0.4	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.5	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	1.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	3.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.7	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.9	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.7	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	1.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.5	GO:0045545	syndecan binding(GO:0045545)
0.0	1.3	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.4	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0070404	NADH binding(GO:0070404)
0.0	0.3	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.2	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0	0.5	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.4	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.4	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	6.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	5.1	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	1.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.5	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.1	GO:0031762	alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) platelet activating factor receptor binding(GO:0031859)
0.0	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.7	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.3	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0031177	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.0	3.4	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.2	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.3	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	4.5	GO:0042393	histone binding(GO:0042393)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.4	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.5	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.5	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.8	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0032810	sterol response element binding(GO:0032810)
0.0	0.1	GO:0000989	transcription factor activity, transcription factor binding(GO:0000989)
0.0	0.1	GO:0097001	ceramide binding(GO:0097001)
0.0	0.1	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.3	GO:1990763	arrestin family protein binding(GO:1990763)
0.0	0.2	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.4	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.7	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.4	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.3	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.2	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.7	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.3	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.7	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.7	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.3	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.1	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0003909	DNA ligase activity(GO:0003909)
0.0	1.9	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.4	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.4	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.1	GO:0015235	cobalamin transporter activity(GO:0015235)
0.0	0.2	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.2	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0052725	inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.4	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.4	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.3	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	1.0	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.5	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.6	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0033857	inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.3	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0031748	D1 dopamine receptor binding(GO:0031748)
0.0	0.0	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.2	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.1	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.9	GO:0004386	helicase activity(GO:0004386)
0.0	0.8	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.0	GO:0001054	RNA polymerase I activity(GO:0001054)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	1.7	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.9	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.6	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.5	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	1.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.5	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	1.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.8	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	5.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	3.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	1.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	3.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	2.0	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.9	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.3	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.7	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.8	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.9	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.5	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.9	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.6	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	1.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.2	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	32.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.4	28.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	2.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	4.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	1.8	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	2.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	2.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	0.7	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	3.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.9	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	1.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	2.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	2.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	1.7	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.8	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	4.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	3.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.2	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.3	1.1	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.3	1.1	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3	0.8	GO:0060127	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2	0.6	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2	1.0	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2	1.0	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1	0.4	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1	0.5	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	0.3	GO:0051795	positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1	0.3	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.1	0.6	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1	0.2	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1	0.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	1.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.5	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.4	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.1	0.4	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0	0.1	GO:0035378	carbon dioxide transmembrane transport(GO:0035378)
0.0	0.1	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.0	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0090611	mitotic cytokinesis checkpoint(GO:0044878) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0	0.4	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.2	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0032900	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.2	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.0	0.3	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.0	0.2	GO:0010748	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.5	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0	0.2	GO:0015692	lead ion transport(GO:0015692)
0.0	0.7	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.4	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0	0.2	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0	0.3	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.7	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722) glycerol transport(GO:0015793) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.0	0.5	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.3	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.0	GO:0016199	axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0	1.7	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.1	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.2	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.5	GO:0006068	ethanol catabolic process(GO:0006068) sulfation(GO:0051923)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.8	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.1	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0061743	motor learning(GO:0061743)
0.0	0.1	GO:1990418	response to insulin-like growth factor stimulus(GO:1990418)
0.0	0.9	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0	0.0	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0	0.0	GO:1901994	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.1	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0	0.1	GO:0009956	radial pattern formation(GO:0009956)
0.0	0.1	GO:0021759	globus pallidus development(GO:0021759)
0.0	0.1	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.2	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.4	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.2	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0021815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0	0.1	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.0	0.1	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	0.6	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	0.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	2.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	1.0	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	1.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	3.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	2.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	1.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.6	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.6	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	GO:0005588	collagen type V trimer(GO:0005588)
0.8	14.0	GO:0032059	bleb(GO:0032059)
0.8	2.4	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.8	3.0	GO:0043259	laminin-10 complex(GO:0043259)
0.6	5.7	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6	1.2	GO:0043260	laminin-11 complex(GO:0043260)
0.5	3.1	GO:1990584	cardiac Troponin complex(GO:1990584)
0.5	3.1	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.5	5.1	GO:0071953	elastic fiber(GO:0071953)
0.5	8.5	GO:0005861	troponin complex(GO:0005861)
0.5	0.5	GO:0019034	viral replication complex(GO:0019034)
0.4	0.9	GO:0032982	myosin filament(GO:0032982)
0.4	5.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.4	1.2	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.4	7.3	GO:0031089	platelet dense granule lumen(GO:0031089)
0.4	1.5	GO:0031673	H zone(GO:0031673)
0.4	4.6	GO:0097418	neurofibrillary tangle(GO:0097418)
0.4	3.3	GO:0034464	BBSome(GO:0034464)
0.4	1.8	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.3	2.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.3	1.7	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.3	1.7	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.3	9.3	GO:0031143	pseudopodium(GO:0031143)
0.3	2.9	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3	1.3	GO:1990246	uniplex complex(GO:1990246)
0.3	1.3	GO:0045160	myosin I complex(GO:0045160)
0.3	3.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3	3.8	GO:0099634	postsynaptic specialization membrane(GO:0099634)
0.3	3.2	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.3	0.3	GO:0042721	mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3	1.2	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.3	0.9	GO:0020005	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.3	3.8	GO:0097470	ribbon synapse(GO:0097470)
0.3	1.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.3	3.5	GO:0097512	cardiac myofibril(GO:0097512)
0.3	3.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.3	10.8	GO:0000421	autophagosome membrane(GO:0000421)
0.3	2.0	GO:0036021	endolysosome lumen(GO:0036021)
0.3	1.1	GO:1990730	VCP-NSFL1C complex(GO:1990730)
0.3	0.3	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.3	2.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.3	1.9	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.3	2.9	GO:0002116	semaphorin receptor complex(GO:0002116)
0.3	0.5	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3	2.0	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	1.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	1.0	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2	1.2	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	2.9	GO:0031595	nuclear proteasome complex(GO:0031595)
0.2	2.6	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	2.6	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.2	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.2	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	5.8	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2	1.1	GO:0001940	male pronucleus(GO:0001940)
0.2	3.4	GO:0030478	actin cap(GO:0030478)
0.2	21.4	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2	1.1	GO:0042643	actomyosin, actin portion(GO:0042643)
0.2	0.7	GO:1902636	kinociliary basal body(GO:1902636)
0.2	1.8	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.2	0.7	GO:0033565	ESCRT-0 complex(GO:0033565)
0.2	1.3	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.2	0.9	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	1.8	GO:0035976	AP1 complex(GO:0035976)
0.2	3.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.2	3.2	GO:0000124	SAGA complex(GO:0000124)
0.2	0.8	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	3.8	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.2	0.4	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.2	1.2	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.2	2.8	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.2	0.4	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.2	17.7	GO:0005604	basement membrane(GO:0005604)
0.2	8.1	GO:0031430	M band(GO:0031430)
0.2	4.1	GO:0005859	muscle myosin complex(GO:0005859)
0.2	1.0	GO:0070826	paraferritin complex(GO:0070826)
0.2	1.7	GO:0005638	lamin filament(GO:0005638)
0.2	1.2	GO:0005915	zonula adherens(GO:0005915)
0.2	1.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	4.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.2	0.8	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	0.7	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.2	1.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.2	2.2	GO:0008091	spectrin(GO:0008091)
0.2	3.6	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	2.5	GO:0098644	complex of collagen trimers(GO:0098644)
0.2	3.9	GO:0000145	exocyst(GO:0000145)
0.2	0.5	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.2	1.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2	1.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.2	3.5	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.2	0.8	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.2	3.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.2	4.2	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.2	1.3	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.2	1.8	GO:0016600	flotillin complex(GO:0016600)
0.2	1.2	GO:1990812	growth cone filopodium(GO:1990812)
0.2	0.3	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.2	1.8	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.2	2.1	GO:1990023	mitotic spindle midzone(GO:1990023)
0.2	1.1	GO:0000813	ESCRT I complex(GO:0000813)
0.2	1.1	GO:0005787	signal peptidase complex(GO:0005787)
0.2	4.5	GO:0005921	gap junction(GO:0005921)
0.2	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	2.2	GO:0044754	autolysosome(GO:0044754)
0.2	4.4	GO:0043034	costamere(GO:0043034)
0.2	1.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.2	0.9	GO:0031527	filopodium membrane(GO:0031527)
0.2	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.2	1.5	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.2	0.5	GO:0016935	glycine-gated chloride channel complex(GO:0016935)
0.2	0.5	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.1	9.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	0.4	GO:0070578	RISC-loading complex(GO:0070578)
0.1	4.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.4	GO:0032807	DNA ligase IV complex(GO:0032807)
0.1	0.3	GO:0044308	axonal spine(GO:0044308)
0.1	41.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	1.0	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1	4.0	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1	0.8	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	6.7	GO:0043198	dendritic shaft(GO:0043198)
0.1	0.7	GO:0097149	centralspindlin complex(GO:0097149)
0.1	0.3	GO:0045120	pronucleus(GO:0045120)
0.1	0.7	GO:0033263	CORVET complex(GO:0033263)
0.1	0.4	GO:0070435	Shc-EGFR complex(GO:0070435)
0.1	0.5	GO:0032044	DSIF complex(GO:0032044)
0.1	1.8	GO:0031209	SCAR complex(GO:0031209)
0.1	1.5	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	1.0	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	2.0	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.1	GO:0016460	myosin II complex(GO:0016460)
0.1	2.8	GO:0030863	cortical cytoskeleton(GO:0030863)
0.1	0.8	GO:0097165	nuclear stress granule(GO:0097165)
0.1	0.8	GO:0016272	prefoldin complex(GO:0016272)
0.1	1.6	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	7.0	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	0.7	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	23.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.5	GO:0097224	sperm connecting piece(GO:0097224)
0.1	1.5	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.5	GO:0031302	intrinsic component of endosome membrane(GO:0031302)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	0.8	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.4	GO:0043293	apoptosome(GO:0043293)
0.1	1.3	GO:0005833	hemoglobin complex(GO:0005833)
0.1	0.3	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.1	GO:0016342	catenin complex(GO:0016342)
0.1	1.5	GO:0042641	actomyosin(GO:0042641)
0.1	1.8	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	1.5	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.3	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	1.1	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.5	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	1.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.4	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	0.1	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.1	0.4	GO:0033186	CAF-1 complex(GO:0033186)
0.1	3.0	GO:0097546	ciliary base(GO:0097546)
0.1	0.3	GO:0005873	plus-end kinesin complex(GO:0005873)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.9	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	1.1	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.4	GO:0070985	TFIIK complex(GO:0070985)
0.1	0.3	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1	8.5	GO:0005901	caveola(GO:0005901)
0.1	0.5	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	0.9	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	2.3	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.9	GO:0005902	microvillus(GO:0005902)
0.1	0.3	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.7	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.1	10.2	GO:0030016	myofibril(GO:0030016)
0.1	0.2	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	44.8	GO:0005925	focal adhesion(GO:0005925)
0.1	0.7	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	0.7	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1	0.5	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	0.5	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1	1.2	GO:0005869	dynactin complex(GO:0005869)
0.1	0.4	GO:0070852	cell body fiber(GO:0070852)
0.1	1.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.5	GO:0071437	invadopodium(GO:0071437)
0.1	0.6	GO:0097361	CIA complex(GO:0097361)
0.1	0.8	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	0.3	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	9.3	GO:0030496	midbody(GO:0030496)
0.1	0.3	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1	0.6	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.1	5.5	GO:0036064	ciliary basal body(GO:0036064)
0.1	0.5	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.9	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.8	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	0.3	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:0035371	microtubule plus-end(GO:0035371)
0.1	0.2	GO:0030891	VCB complex(GO:0030891)
0.1	0.2	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.5	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.2	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1	0.2	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	0.2	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.1	1.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.3	GO:0060091	kinocilium(GO:0060091)
0.1	0.5	GO:0072687	meiotic spindle(GO:0072687)
0.1	0.4	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	1.4	GO:0030904	retromer complex(GO:0030904)
0.1	1.7	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	0.6	GO:0033643	host cell part(GO:0033643)
0.1	1.8	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.2	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	1.9	GO:0031305	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1	0.3	GO:0032301	MutSalpha complex(GO:0032301)
0.1	0.5	GO:0031415	NatA complex(GO:0031415)
0.1	1.0	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.6	GO:0061574	ASAP complex(GO:0061574)
0.1	3.7	GO:0072686	mitotic spindle(GO:0072686)
0.1	0.4	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.1	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1	0.4	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1	0.8	GO:0017119	Golgi transport complex(GO:0017119)
0.1	0.3	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.8	GO:0005838	proteasome regulatory particle(GO:0005838)
0.1	0.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	2.0	GO:0030175	filopodium(GO:0030175)
0.1	4.3	GO:0030027	lamellipodium(GO:0030027)
0.1	0.5	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.1	1.5	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.2	GO:0070939	Dsl1p complex(GO:0070939)
0.1	0.4	GO:0045178	basal part of cell(GO:0045178)
0.1	0.4	GO:0097440	apical dendrite(GO:0097440)
0.1	0.8	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.1	GO:0045180	basal cortex(GO:0045180)
0.1	0.4	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	0.1	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.1	GO:0044292	dendrite terminus(GO:0044292)
0.1	0.5	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.1	0.3	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	1.5	GO:0005581	collagen trimer(GO:0005581)
0.1	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.1	GO:0097449	astrocyte projection(GO:0097449)
0.1	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.1	3.0	GO:0043195	terminal bouton(GO:0043195)
0.1	0.1	GO:0098984	symmetric synapse(GO:0032280) neuron to neuron synapse(GO:0098984)
0.1	1.7	GO:0005685	U1 snRNP(GO:0005685)
0.1	1.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	0.2	GO:0043291	RAVE complex(GO:0043291)
0.1	0.1	GO:0042382	paraspeckles(GO:0042382)
0.1	0.4	GO:0044327	dendritic spine head(GO:0044327)
0.1	0.6	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.1	0.5	GO:0036452	ESCRT complex(GO:0036452)
0.1	0.3	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.4	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	3.3	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.2	GO:0031091	platelet alpha granule(GO:0031091)
0.0	0.0	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	1.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	2.0	GO:0031201	SNARE complex(GO:0031201)
0.0	3.4	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.0	0.2	GO:0005687	U4 snRNP(GO:0005687)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.3	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:1990393	3M complex(GO:1990393)
0.0	0.3	GO:0042788	polysomal ribosome(GO:0042788)
0.0	3.7	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	4.9	GO:0031012	extracellular matrix(GO:0031012)
0.0	5.4	GO:0001726	ruffle(GO:0001726)
0.0	1.0	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	1.5	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.3	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.3	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.0	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.0	0.4	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.7	GO:0097342	ripoptosome(GO:0097342)
0.0	0.1	GO:0002177	manchette(GO:0002177)
0.0	0.2	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.4	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0035859	Seh1-associated complex(GO:0035859)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.5	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.7	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0	0.1	GO:0031310	intrinsic component of vacuolar membrane(GO:0031310)
0.0	0.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.7	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0071439	clathrin complex(GO:0071439)
0.0	0.6	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	0.6	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	1.4	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.8	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.2	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0016938	kinesin I complex(GO:0016938)
0.0	0.8	GO:0005776	autophagosome(GO:0005776)
0.0	0.2	GO:0070187	telosome(GO:0070187)
0.0	0.2	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.4	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.0	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.2	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.0	0.3	GO:0034706	sodium channel complex(GO:0034706)
0.0	1.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.2	GO:0034709	methylosome(GO:0034709)
0.0	0.2	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.2	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.0	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.7	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.2	GO:0045495	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0	0.0	GO:0055087	Ski complex(GO:0055087)
0.0	0.7	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.4	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.7	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	1.0	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	5.6	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0032144	4-aminobutyrate transaminase complex(GO:0032144)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	0.0	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.0	GO:0071020	post-spliceosomal complex(GO:0071020)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.6	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.2	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.0	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.1	GO:0097227	sperm annulus(GO:0097227)
0.0	0.1	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.0	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	5.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	4.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	2.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	2.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	3.3	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	1.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	1.2	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	1.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	9.8	GO:0005588	collagen type V trimer(GO:0005588)
2.7	37.3	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.2	11.7	GO:0071953	elastic fiber(GO:0071953)
1.0	19.6	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
1.0	5.2	GO:0071148	TEAD-1-YAP complex(GO:0071148)
1.0	10.7	GO:0071438	invadopodium membrane(GO:0071438)
0.9	3.8	GO:0045160	myosin I complex(GO:0045160)
0.8	2.4	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.6	4.1	GO:0036021	endolysosome lumen(GO:0036021)
0.6	2.8	GO:0005899	insulin receptor complex(GO:0005899)
0.5	3.2	GO:1990130	EGO complex(GO:0034448) Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5	1.4	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.5	6.9	GO:0030478	actin cap(GO:0030478)
0.4	4.8	GO:0005614	interstitial matrix(GO:0005614)
0.3	1.2	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3	4.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.3	1.3	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2	1.7	GO:0005593	FACIT collagen trimer(GO:0005593)
0.2	1.5	GO:0016012	sarcoglycan complex(GO:0016012)
0.2	0.7	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2	3.5	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.2	0.8	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	5.0	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	1.0	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.2	1.1	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1	1.3	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	3.5	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.3	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.1	14.8	GO:0005604	basement membrane(GO:0005604)
0.1	1.9	GO:0008091	spectrin(GO:0008091)
0.1	8.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	8.4	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	1.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	3.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	3.1	GO:0032587	ruffle membrane(GO:0032587)
0.1	3.3	GO:0000421	autophagosome membrane(GO:0000421)
0.1	0.7	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1	1.5	GO:0097512	cardiac myofibril(GO:0097512)
0.1	0.7	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.7	GO:0098644	complex of collagen trimers(GO:0098644)
0.1	0.3	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.1	5.9	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	0.2	GO:0097679	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1	0.9	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.3	GO:0070826	paraferritin complex(GO:0070826)
0.1	1.5	GO:0030286	dynein complex(GO:0030286)
0.1	1.9	GO:0051233	spindle midzone(GO:0051233)
0.1	1.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	2.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.0	GO:0032433	filopodium tip(GO:0032433)
0.0	0.5	GO:0033391	chromatoid body(GO:0033391)
0.0	6.4	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.5	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	1.2	GO:0099738	cell cortex region(GO:0099738)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	1.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.8	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	1.5	GO:1904115	axon cytoplasm(GO:1904115)
0.0	1.6	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.7	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	5.1	GO:0005795	Golgi stack(GO:0005795)
0.0	0.5	GO:0005883	neurofilament(GO:0005883)
0.0	9.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	1.9	GO:0005902	microvillus(GO:0005902)
0.0	0.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.7	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	3.4	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.1	GO:0030123	AP-3 adaptor complex(GO:0030123) CORVET complex(GO:0033263)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.3	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:1990752	microtubule end(GO:1990752)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	1.4	GO:0005811	lipid particle(GO:0005811)
0.0	1.7	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.0	0.3	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.6	GO:0045095	keratin filament(GO:0045095)
0.0	2.6	GO:0030426	growth cone(GO:0030426)
0.0	0.0	GO:0097449	eukaryotic translation initiation factor 2 complex(GO:0005850) astrocyte projection(GO:0097449)
0.0	0.8	GO:0055037	recycling endosome(GO:0055037)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.6	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.6	GO:0005776	autophagosome(GO:0005776)
0.0	1.0	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0005861	troponin complex(GO:0005861)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.4	GO:0005588	collagen type V trimer(GO:0005588)
0.5	1.4	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4	5.9	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4	3.9	GO:0097413	Lewy body(GO:0097413)
0.4	1.9	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.3	1.3	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2	1.5	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.2	2.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	1.6	GO:0036021	endolysosome lumen(GO:0036021)
0.2	2.0	GO:0071953	elastic fiber(GO:0071953)
0.2	2.4	GO:0008091	spectrin(GO:0008091)
0.2	0.5	GO:0045293	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1	1.6	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	1.2	GO:0072687	meiotic spindle(GO:0072687)
0.1	4.6	GO:0000421	autophagosome membrane(GO:0000421)
0.1	2.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.1	1.5	GO:0097470	ribbon synapse(GO:0097470)
0.1	1.3	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.7	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.8	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.5	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.1	1.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	2.4	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	1.2	GO:0031209	SCAR complex(GO:0031209)
0.1	0.4	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	2.7	GO:1904115	axon cytoplasm(GO:1904115)
0.1	0.9	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.0	0.9	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	1.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.8	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.6	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	1.3	GO:0008305	integrin complex(GO:0008305)
0.0	0.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0097342	ripoptosome(GO:0097342)
0.0	0.4	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.1	GO:0071159	NF-kappaB complex(GO:0071159)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.6	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.8	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.4	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.1	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.9	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	3.5	GO:0019898	extrinsic component of membrane(GO:0019898)
0.0	1.6	GO:0005795	Golgi stack(GO:0005795)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	21.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	5.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	4.8	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	7.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	2.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	20.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	3.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	6.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	1.7	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	3.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	5.3	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	4.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.1	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	1.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.3	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	2.1	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.7	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME OPSINS	Genes involved in Opsins
0.0	0.9	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.7	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	2.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	2.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	3.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	6.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.4	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1	1.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.1	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	1.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	1.6	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4	1.2	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4	1.1	GO:0007439	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.4	1.1	GO:0097359	UDP-glucosylation(GO:0097359)
0.4	1.1	GO:2000097	chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4	1.1	GO:1904933	cardiac right atrium morphogenesis(GO:0003213) negative regulation of melanin biosynthetic process(GO:0048022) positive regulation of anagen(GO:0051885) mediolateral intercalation(GO:0060031) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) negative regulation of secondary metabolite biosynthetic process(GO:1900377) regulation of cell proliferation in midbrain(GO:1904933)
0.3	2.0	GO:0001692	histamine metabolic process(GO:0001692)
0.3	1.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.3	1.4	GO:0071279	cellular response to cobalt ion(GO:0071279)
0.3	0.9	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.3	0.8	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2	0.4	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.2	1.0	GO:1900127	renal water absorption(GO:0070295) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.2	1.0	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.2	0.7	GO:0034445	negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2	0.6	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.2	1.0	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.2	0.5	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.6	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1	0.6	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.4	GO:0006014	D-ribose metabolic process(GO:0006014)
0.1	0.4	GO:0003383	apical constriction(GO:0003383) mesoderm migration involved in gastrulation(GO:0007509)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.4	GO:0032887	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1	0.3	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.6	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	0.4	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1	0.8	GO:0051414	response to cortisol(GO:0051414)
0.1	0.6	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.4	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1	0.4	GO:0060613	fat pad development(GO:0060613)
0.1	0.3	GO:1900195	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.1	0.3	GO:0052331	hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1	0.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.4	GO:0044375	regulation of peroxisome size(GO:0044375)
0.1	0.5	GO:1903564	regulation of protein localization to cilium(GO:1903564)
0.1	0.5	GO:0036369	transcription factor catabolic process(GO:0036369)
0.1	0.3	GO:0046440	L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1	0.5	GO:0042713	sperm ejaculation(GO:0042713)
0.1	0.7	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	0.8	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1	0.3	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1	0.2	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	0.3	GO:0051754	meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1	0.5	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.1	0.2	GO:2000395	ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1	0.4	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	1.0	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.1	0.3	GO:0071494	positive regulation of translational initiation in response to stress(GO:0032058) cellular response to UV-C(GO:0071494)
0.1	5.5	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.2	GO:0060296	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1	0.4	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.1	0.8	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1	0.2	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.1	0.6	GO:1902416	positive regulation of mRNA binding(GO:1902416)
0.1	0.2	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1	0.2	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.1	0.3	GO:0097338	response to clozapine(GO:0097338)
0.1	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.5	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	0.2	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1	0.2	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	0.2	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1	0.2	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1	0.5	GO:0006983	ER overload response(GO:0006983)
0.1	0.2	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.1	0.4	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.4	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1	0.4	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.2	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.2	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.0	0.7	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.3	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.0	0.6	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.4	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	0.1	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.0	0.3	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.4	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.3	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.2	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.6	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.8	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.3	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	2.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.1	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0	0.1	GO:0032053	ciliary basal body organization(GO:0032053)
0.0	0.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0	0.1	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.5	GO:0000338	protein deneddylation(GO:0000338)
0.0	1.4	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.2	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.0	1.5	GO:0035666	TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0	0.5	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.1	GO:1904046	negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0	0.3	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.1	GO:2000705	dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.2	GO:0051013	microtubule severing(GO:0051013)
0.0	0.4	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.2	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.1	GO:0030397	mitotic nuclear envelope disassembly(GO:0007077) membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.8	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:1903722	regulation of centriole elongation(GO:1903722)
0.0	0.2	GO:0009597	detection of virus(GO:0009597)
0.0	0.3	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	1.0	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.0	GO:0018307	enzyme active site formation(GO:0018307)
0.0	0.1	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.0	0.4	GO:0032607	interferon-alpha production(GO:0032607)
0.0	0.5	GO:0036120	cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0	0.1	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.0	0.2	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0061743	motor learning(GO:0061743)
0.0	0.8	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.6	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.0	0.1	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.0	0.1	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
0.0	0.1	GO:0060215	primitive hemopoiesis(GO:0060215)
0.0	0.4	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0	0.1	GO:0042631	cellular response to water deprivation(GO:0042631)
0.0	0.5	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.8	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.1	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.2	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.1	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.3	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.1	GO:1904688	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0	0.2	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.1	GO:0023035	CD40 signaling pathway(GO:0023035)
0.0	0.1	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.5	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	0.4	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.3	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.2	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.3	GO:0045444	fat cell differentiation(GO:0045444)
0.0	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.3	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.0	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.0	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.1	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.0	0.1	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0002863	positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0	0.2	GO:0043462	regulation of ATPase activity(GO:0043462)
0.0	0.2	GO:0030316	osteoclast differentiation(GO:0030316)
0.0	0.2	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.0	GO:0050670	regulation of mononuclear cell proliferation(GO:0032944) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.0	0.1	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.2	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.8	GO:0018410	C-terminal protein amino acid modification(GO:0018410)
0.0	0.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.2	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.2	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.2	GO:0003014	renal system process(GO:0003014)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	9.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.7	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	6.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.6	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	3.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	2.0	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.0	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	1.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.7	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.8	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	1.8	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	1.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	1.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.6	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	1.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.9	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	1.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	1.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	8.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	9.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.9	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	6.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.9	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.1	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	4.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	2.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.5	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	2.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.5	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	1.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.1	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.4	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	35.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
1.5	44.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.6	13.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.6	8.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4	13.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	2.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4	6.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.4	11.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.4	32.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.3	1.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.3	3.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.3	4.7	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.3	6.9	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.3	1.8	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.2	6.8	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	4.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.2	8.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	5.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	4.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	6.3	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.2	2.9	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	3.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	3.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.2	2.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	2.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	4.8	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	2.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	12.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	3.6	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	5.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	0.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	0.7	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.1	3.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	1.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	4.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	6.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	3.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.1	1.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	2.8	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.1	1.7	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	6.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.2	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.1	1.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	4.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	3.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.0	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	1.5	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	0.5	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	3.0	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	1.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	0.9	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	1.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	0.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	3.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	2.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.8	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.0	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.0	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.3	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	1.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.4	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.6	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.5	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.4	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.6	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	3.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.8	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	4.6	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.5	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.2	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.2	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

Results for T

Z-value: 0.71

Motif logo

Transcription factors associated with T

Activity-expression correlation:

Activity profile of T motif

Sorted Z-values of T motif

Network of associatons between targets according to the STRING database.

First level regulatory network of T

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

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Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP:REACTOME category:

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Gene overrepresentation in biological_process category:

Gene overrepresentation in C2:CP:REACTOME category:

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Gene overrepresentation in molecular_function category:

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Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

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Gene overrepresentation in biological_process category:

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Gene overrepresentation in C2:CP category:

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Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in cellular_component category: