ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
TBP Links Ensembl NCBI GeneCards UniProt	ENSG00000112592.8	TBP

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TBP	hg19_v2_chr6_+_170863421_170863484	-0.32	2.3e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr16_+_56685796	10.23	ENST00000334346.2 ENST00000562399.1	MT1B	metallothionein 1B
chr12_-_52845910	9.98	ENST00000252252.3	KRT6B	keratin 6B
chr12_-_52867569	8.35	ENST00000252250.6	KRT6C	keratin 6C
chr10_+_54074033	7.40	ENST00000373970.3	DKK1	dickkopf WNT signaling pathway inhibitor 1
chr17_-_39780819	7.30	ENST00000311208.8	KRT17	keratin 17
chr1_+_153003671	7.00	ENST00000307098.4	SPRR1B	small proline-rich protein 1B
chr1_-_59043166	6.54	ENST00000371225.2	TACSTD2	tumor-associated calcium signal transducer 2
chr1_-_153538011	6.36	ENST00000368707.4	S100A2	S100 calcium binding protein A2
chr1_-_153363452	6.02	ENST00000368732.1 ENST00000368733.3	S100A8	S100 calcium binding protein A8
chr17_-_39674668	5.98	ENST00000393981.3	KRT15	keratin 15
chr3_+_122044084	5.91	ENST00000264474.3 ENST00000479204.1	CSTA	cystatin A (stefin A)
chr12_-_53012343	5.87	ENST00000305748.3	KRT73	keratin 73
chr16_+_56659687	5.78	ENST00000568293.1 ENST00000330439.6	MT1E	metallothionein 1E
chr21_-_28217721	5.66	ENST00000284984.3	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_+_153330322	5.48	ENST00000368738.3	S100A9	S100 calcium binding protein A9
chr15_-_63674034	5.47	ENST00000344366.3 ENST00000422263.2	CA12	carbonic anhydrase XII
chr20_-_43883197	5.29	ENST00000338380.2	SLPI	secretory leukocyte peptidase inhibitor
chr3_-_111314230	4.97	ENST00000317012.4	ZBED2	zinc finger, BED-type containing 2
chr11_-_2950642	4.95	ENST00000314222.4	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr15_-_63674218	4.92	ENST00000178638.3	CA12	carbonic anhydrase XII
chr2_-_151344172	4.66	ENST00000375734.2 ENST00000263895.4 ENST00000454202.1	RND3	Rho family GTPase 3
chr1_-_209825674	4.62	ENST00000367030.3 ENST00000356082.4	LAMB3	laminin, beta 3
chr16_+_56703737	4.31	ENST00000569155.1	MT1H	metallothionein 1H
chr12_+_6309517	4.30	ENST00000382519.4 ENST00000009180.4	CD9	CD9 molecule
chr16_+_56703703	4.18	ENST00000332374.4	MT1H	metallothionein 1H
chr3_+_62304712	4.12	ENST00000494481.1	C3orf14	chromosome 3 open reading frame 14
chr5_-_57756087	4.08	ENST00000274289.3	PLK2	polo-like kinase 2
chr3_+_62304648	3.90	ENST00000462069.1 ENST00000232519.5 ENST00000465142.1	C3orf14	chromosome 3 open reading frame 14
chr1_-_95007193	3.86	ENST00000370207.4 ENST00000334047.7	F3	coagulation factor III (thromboplastin, tissue factor)
chr16_+_56691606	3.67	ENST00000334350.6	MT1F	metallothionein 1F
chr1_+_152881014	3.33	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr4_+_169842707	3.19	ENST00000503290.1	PALLD	palladin, cytoskeletal associated protein
chr4_+_74735102	3.11	ENST00000395761.3	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr16_-_56701933	2.95	ENST00000568675.1 ENST00000569500.1 ENST00000444837.2 ENST00000379811.3	MT1G	metallothionein 1G
chr3_+_190333097	2.91	ENST00000412080.1	IL1RAP	interleukin 1 receptor accessory protein
chr2_-_106054952	2.83	ENST00000336660.5 ENST00000393352.3 ENST00000607522.1	FHL2	four and a half LIM domains 2
chr6_-_134495992	2.79	ENST00000475719.2 ENST00000367857.5 ENST00000237305.7	SGK1	serum/glucocorticoid regulated kinase 1
chr14_+_75745477	2.69	ENST00000303562.4 ENST00000554617.1 ENST00000554212.1 ENST00000535987.1 ENST00000555242.1	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr16_+_56691911	2.61	ENST00000568475.1	MT1F	metallothionein 1F
chr16_+_56598961	2.56	ENST00000219162.3	MT4	metallothionein 4
chr17_-_74707037	2.47	ENST00000355797.3 ENST00000375036.2 ENST00000449428.2	MXRA7	matrix-remodelling associated 7
chr10_-_126716459	2.42	ENST00000309035.6	CTBP2	C-terminal binding protein 2
chr11_+_62623621	2.40	ENST00000535296.1	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr8_-_23261589	2.40	ENST00000524168.1 ENST00000523833.2 ENST00000519243.1 ENST00000389131.3	LOXL2	lysyl oxidase-like 2
chr11_+_18287721	2.37	ENST00000356524.4	SAA1	serum amyloid A1
chr1_+_86046433	2.33	ENST00000451137.2	CYR61	cysteine-rich, angiogenic inducer, 61
chr19_-_50143452	2.30	ENST00000246792.3	RRAS	related RAS viral (r-ras) oncogene homolog
chr6_+_31783291	2.28	ENST00000375651.5 ENST00000608703.1 ENST00000458062.2	HSPA1A	heat shock 70kDa protein 1A
chr19_-_45982076	2.27	ENST00000423698.2	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr11_+_18287801	2.23	ENST00000532858.1 ENST00000405158.2	SAA1	serum amyloid A1
chr3_+_142342228	2.05	ENST00000337777.3	PLS1	plastin 1
chr12_-_52685312	1.99	ENST00000327741.5	KRT81	keratin 81
chr14_+_65007177	1.97	ENST00000247207.6	HSPA2	heat shock 70kDa protein 2
chr3_+_101546827	1.97	ENST00000461724.1 ENST00000483180.1 ENST00000394054.2	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_-_43424500	1.95	ENST00000415851.2 ENST00000426263.3 ENST00000372500.3	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr12_-_53074182	1.93	ENST00000252244.3	KRT1	keratin 1
chr17_-_39553844	1.88	ENST00000251645.2	KRT31	keratin 31
chr10_+_5135981	1.88	ENST00000380554.3	AKR1C3	aldo-keto reductase family 1, member C3
chr1_-_152297679	1.82	ENST00000368799.1	FLG	filaggrin
chr19_-_6720686	1.82	ENST00000245907.6	C3	complement component 3
chr11_-_18270182	1.80	ENST00000528349.1 ENST00000526900.1 ENST00000529528.1 ENST00000414546.2 ENST00000256733.4	SAA2	serum amyloid A2
chr11_-_102651343	1.79	ENST00000279441.4 ENST00000539681.1	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr1_-_153044083	1.74	ENST00000341611.2	SPRR2B	small proline-rich protein 2B
chr18_-_61329118	1.71	ENST00000332821.8 ENST00000283752.5	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr11_+_62623512	1.66	ENST00000377892.1	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623544	1.65	ENST00000377890.2 ENST00000377891.2 ENST00000377889.2	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_-_153013588	1.65	ENST00000360379.3	SPRR2D	small proline-rich protein 2D
chr20_+_30193083	1.64	ENST00000376112.3 ENST00000376105.3	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr9_-_33447584	1.64	ENST00000297991.4	AQP3	aquaporin 3 (Gill blood group)
chr12_+_4385230	1.64	ENST00000536537.1	CCND2	cyclin D2
chr4_-_169239921	1.59	ENST00000514995.1 ENST00000393743.3	DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_-_182360498	1.57	ENST00000417584.2	GLUL	glutamate-ammonia ligase
chr9_+_130911723	1.56	ENST00000277480.2 ENST00000373013.2 ENST00000540948.1	LCN2	lipocalin 2
chr5_-_16742330	1.53	ENST00000505695.1 ENST00000427430.2	MYO10	myosin X
chr9_+_124088860	1.52	ENST00000373806.1	GSN	gelsolin
chr1_-_182360918	1.52	ENST00000339526.4	GLUL	glutamate-ammonia ligase
chr9_+_130911770	1.51	ENST00000372998.1	LCN2	lipocalin 2
chr1_-_182361327	1.49	ENST00000331872.6 ENST00000311223.5	GLUL	glutamate-ammonia ligase
chr1_-_153518270	1.37	ENST00000354332.4 ENST00000368716.4	S100A4	S100 calcium binding protein A4
chr7_-_41742697	1.35	ENST00000242208.4	INHBA	inhibin, beta A
chr2_-_208030647	1.33	ENST00000309446.6	KLF7	Kruppel-like factor 7 (ubiquitous)
chr19_-_14628645	1.32	ENST00000598235.1	DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr10_+_17271266	1.31	ENST00000224237.5	VIM	vimentin
chr12_+_1738363	1.31	ENST00000397196.2	WNT5B	wingless-type MMTV integration site family, member 5B
chr4_-_74904398	1.30	ENST00000296026.4	CXCL3	chemokine (C-X-C motif) ligand 3
chr1_-_27481401	1.28	ENST00000263980.3	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr5_-_42811986	1.28	ENST00000511224.1 ENST00000507920.1 ENST00000510965.1	SEPP1	selenoprotein P, plasma, 1
chr5_-_42812143	1.28	ENST00000514985.1	SEPP1	selenoprotein P, plasma, 1
chr14_-_102706934	1.24	ENST00000523231.1 ENST00000524370.1 ENST00000517966.1	MOK	MOK protein kinase
chr17_-_39538550	1.22	ENST00000394001.1	KRT34	keratin 34
chr11_-_61735103	1.22	ENST00000529191.1 ENST00000529631.1 ENST00000530019.1 ENST00000529548.1 ENST00000273550.7	FTH1	ferritin, heavy polypeptide 1
chr11_-_33774944	1.21	ENST00000532057.1 ENST00000531080.1	FBXO3	F-box protein 3
chr5_-_74162605	1.21	ENST00000389156.4 ENST00000510496.1 ENST00000380515.3	FAM169A	family with sequence similarity 169, member A
chr4_-_57547454	1.19	ENST00000556376.2	HOPX	HOP homeobox
chr22_+_39916558	1.15	ENST00000337304.2 ENST00000396680.1	ATF4	activating transcription factor 4
chr6_+_26124373	1.14	ENST00000377791.2 ENST00000602637.1	HIST1H2AC	histone cluster 1, H2ac
chr3_-_99595037	1.13	ENST00000383694.2	FILIP1L	filamin A interacting protein 1-like
chr17_+_39411636	1.12	ENST00000394008.1	KRTAP9-9	keratin associated protein 9-9
chrX_-_133792480	1.12	ENST00000359237.4	PLAC1	placenta-specific 1
chr17_+_79008940	1.09	ENST00000392411.3 ENST00000575989.1 ENST00000321280.7 ENST00000428708.2 ENST00000575712.1 ENST00000575245.1 ENST00000435091.3 ENST00000321300.6	BAIAP2	BAI1-associated protein 2
chr6_-_52860171	1.08	ENST00000370963.4	GSTA4	glutathione S-transferase alpha 4
chr8_-_18744528	1.08	ENST00000523619.1	PSD3	pleckstrin and Sec7 domain containing 3
chr4_-_57547870	1.05	ENST00000381260.3 ENST00000420433.1 ENST00000554144.1 ENST00000557328.1	HOPX	HOP homeobox
chr6_-_33239612	1.02	ENST00000482399.1 ENST00000445902.2	VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr6_+_27114861	0.99	ENST00000377459.1	HIST1H2AH	histone cluster 1, H2ah
chr3_+_193853927	0.95	ENST00000232424.3	HES1	hes family bHLH transcription factor 1
chr7_-_30066233	0.93	ENST00000222803.5	FKBP14	FK506 binding protein 14, 22 kDa
chr5_+_66254698	0.91	ENST00000405643.1 ENST00000407621.1 ENST00000432426.1	MAST4	microtubule associated serine/threonine kinase family member 4
chr3_-_126327398	0.89	ENST00000383572.2	TXNRD3NB	thioredoxin reductase 3 neighbor
chr19_-_53636125	0.87	ENST00000601493.1 ENST00000599261.1 ENST00000597503.1 ENST00000500065.4 ENST00000243643.4 ENST00000594011.1 ENST00000455735.2 ENST00000595193.1 ENST00000448501.1 ENST00000421033.1 ENST00000440291.1 ENST00000595813.1 ENST00000600574.1 ENST00000596051.1 ENST00000601110.1	ZNF415	zinc finger protein 415
chr3_-_99594948	0.84	ENST00000471562.1 ENST00000495625.2	FILIP1L	filamin A interacting protein 1-like
chr6_+_111195973	0.84	ENST00000368885.3 ENST00000368882.3 ENST00000451850.2 ENST00000368877.5	AMD1	adenosylmethionine decarboxylase 1
chr5_+_140739537	0.83	ENST00000522605.1	PCDHGB2	protocadherin gamma subfamily B, 2
chr19_+_13049413	0.82	ENST00000316448.5 ENST00000588454.1	CALR	calreticulin
chr18_+_21719018	0.82	ENST00000585037.1 ENST00000415309.2 ENST00000399481.2 ENST00000577705.1 ENST00000327201.6	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr10_+_91152303	0.82	ENST00000371804.3	IFIT1	interferon-induced protein with tetratricopeptide repeats 1
chr7_+_115862858	0.81	ENST00000393481.2	TES	testis derived transcript (3 LIM domains)
chr12_+_130646999	0.81	ENST00000539839.1 ENST00000229030.4	FZD10	frizzled family receptor 10
chr12_-_125399573	0.81	ENST00000339647.5	UBC	ubiquitin C
chr19_+_1026566	0.81	ENST00000348419.3 ENST00000565096.2 ENST00000562958.2 ENST00000562075.2 ENST00000607102.1	CNN2	calponin 2
chrX_+_37208521	0.78	ENST00000378628.4	PRRG1	proline rich Gla (G-carboxyglutamic acid) 1
chr19_+_1026298	0.76	ENST00000263097.4	CNN2	calponin 2
chr16_+_71392616	0.76	ENST00000349553.5 ENST00000302628.4 ENST00000562305.1	CALB2	calbindin 2
chr2_-_43453734	0.75	ENST00000282388.3	ZFP36L2	ZFP36 ring finger protein-like 2
chr9_+_140135665	0.72	ENST00000340384.4	TUBB4B	tubulin, beta 4B class IVb
chr14_-_107211459	0.72	ENST00000390636.2	IGHV3-73	immunoglobulin heavy variable 3-73
chr16_+_82068830	0.72	ENST00000199936.4	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr13_+_45694583	0.72	ENST00000340473.6	GTF2F2	general transcription factor IIF, polypeptide 2, 30kDa
chr18_+_21718924	0.69	ENST00000399496.3	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr22_+_32340481	0.69	ENST00000397492.1	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr8_-_59412717	0.68	ENST00000301645.3	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chr15_-_72523454	0.67	ENST00000565154.1 ENST00000565184.1 ENST00000389093.3 ENST00000449901.2 ENST00000335181.5 ENST00000319622.6	PKM	pyruvate kinase, muscle
chr19_-_6767516	0.66	ENST00000245908.6	SH2D3A	SH2 domain containing 3A
chr1_-_156675368	0.66	ENST00000368222.3	CRABP2	cellular retinoic acid binding protein 2
chrX_-_62974941	0.62	ENST00000374872.1 ENST00000253401.6 ENST00000374870.4	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_-_178128528	0.61	ENST00000397063.4 ENST00000421929.1	NFE2L2	nuclear factor, erythroid 2-like 2
chr20_-_39928705	0.61	ENST00000436099.2 ENST00000309060.3 ENST00000373261.1 ENST00000436440.2 ENST00000540170.1 ENST00000557816.1 ENST00000560361.1	ZHX3	zinc fingers and homeoboxes 3
chr6_+_112375462	0.60	ENST00000361714.1	WISP3	WNT1 inducible signaling pathway protein 3
chr9_+_21409146	0.60	ENST00000380205.1	IFNA8	interferon, alpha 8
chr20_+_18488528	0.60	ENST00000377465.1	SEC23B	Sec23 homolog B (S. cerevisiae)
chr7_+_100273736	0.59	ENST00000412215.1 ENST00000393924.1	GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_149822620	0.58	ENST00000369159.2	HIST2H2AA4	histone cluster 2, H2aa4
chr7_+_75931861	0.58	ENST00000248553.6	HSPB1	heat shock 27kDa protein 1
chr3_-_197025447	0.57	ENST00000346964.2 ENST00000357674.4 ENST00000314062.3 ENST00000448528.2 ENST00000419553.1	DLG1	discs, large homolog 1 (Drosophila)
chr13_+_43597269	0.55	ENST00000379221.2	DNAJC15	DnaJ (Hsp40) homolog, subfamily C, member 15
chr10_-_69455873	0.55	ENST00000433211.2	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr17_-_34345002	0.54	ENST00000293280.2	CCL23	chemokine (C-C motif) ligand 23
chr11_-_118966167	0.54	ENST00000530167.1	H2AFX	H2A histone family, member X
chr17_-_73775839	0.54	ENST00000592643.1 ENST00000591890.1 ENST00000587171.1 ENST00000254810.4 ENST00000589599.1	H3F3B	H3 histone, family 3B (H3.3B)
chr1_+_206223941	0.54	ENST00000367126.4	AVPR1B	arginine vasopressin receptor 1B
chr4_+_26585538	0.54	ENST00000264866.4	TBC1D19	TBC1 domain family, member 19
chr18_+_34124507	0.54	ENST00000591635.1	FHOD3	formin homology 2 domain containing 3
chr22_+_32340447	0.53	ENST00000248975.5	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr11_+_133938820	0.52	ENST00000299106.4 ENST00000529443.2	JAM3	junctional adhesion molecule 3
chr21_-_43786634	0.51	ENST00000291527.2	TFF1	trefoil factor 1
chr13_+_53602894	0.51	ENST00000219022.2	OLFM4	olfactomedin 4
chr10_-_79397479	0.51	ENST00000404771.3	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_-_33168336	0.51	ENST00000373484.3	SYNC	syncoilin, intermediate filament protein
chr16_+_89989687	0.50	ENST00000315491.7 ENST00000555576.1 ENST00000554336.1 ENST00000553967.1	TUBB3	Tubulin beta-3 chain
chr9_+_108320392	0.50	ENST00000602661.1 ENST00000223528.2 ENST00000448551.2 ENST00000540160.1	FKTN	fukutin
chr6_-_26124138	0.50	ENST00000314332.5 ENST00000396984.1	HIST1H2BC	histone cluster 1, H2bc
chr8_-_6735451	0.50	ENST00000297439.3	DEFB1	defensin, beta 1
chrX_-_7895755	0.50	ENST00000444736.1 ENST00000537427.1 ENST00000442940.1	PNPLA4	patatin-like phospholipase domain containing 4
chr1_-_45987526	0.49	ENST00000372079.1 ENST00000262746.1 ENST00000447184.1 ENST00000319248.8	PRDX1	peroxiredoxin 1
chr20_+_31823792	0.49	ENST00000375413.4 ENST00000354297.4 ENST00000375422.2	BPIFA1	BPI fold containing family A, member 1
chr1_+_202830876	0.49	ENST00000456105.2	RP11-480I12.7	RP11-480I12.7
chr12_+_11081828	0.49	ENST00000381847.3 ENST00000396400.3	PRH2	proline-rich protein HaeIII subfamily 2
chr9_-_130639997	0.47	ENST00000373176.1	AK1	adenylate kinase 1
chr5_-_158757895	0.47	ENST00000231228.2	IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr1_-_207226313	0.46	ENST00000367084.1	YOD1	YOD1 deubiquitinase
chrX_-_7895479	0.46	ENST00000381042.4	PNPLA4	patatin-like phospholipase domain containing 4
chr12_+_124155652	0.45	ENST00000426174.2 ENST00000303372.5	TCTN2	tectonic family member 2
chr6_+_136172820	0.44	ENST00000308191.6	PDE7B	phosphodiesterase 7B
chr1_-_149814478	0.44	ENST00000369161.3	HIST2H2AA3	histone cluster 2, H2aa3
chr20_+_2276639	0.44	ENST00000381458.5	TGM3	transglutaminase 3
chr6_+_31802364	0.44	ENST00000375640.3 ENST00000375641.2	C6orf48	chromosome 6 open reading frame 48
chr11_-_61734599	0.44	ENST00000532601.1	FTH1	ferritin, heavy polypeptide 1
chr12_-_118796910	0.44	ENST00000541186.1 ENST00000539872.1	TAOK3	TAO kinase 3
chr6_-_33239712	0.43	ENST00000436044.2	VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr20_-_39928756	0.43	ENST00000432768.2	ZHX3	zinc fingers and homeoboxes 3
chr14_+_56127989	0.42	ENST00000555573.1	KTN1	kinectin 1 (kinesin receptor)
chr6_-_136847610	0.42	ENST00000454590.1 ENST00000432797.2	MAP7	microtubule-associated protein 7
chr11_-_14380664	0.41	ENST00000545643.1 ENST00000256196.4	RRAS2	related RAS viral (r-ras) oncogene homolog 2
chr19_-_55866104	0.41	ENST00000326529.4	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr11_-_47400062	0.41	ENST00000533030.1	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene
chr10_+_32856764	0.40	ENST00000375030.2 ENST00000375028.3	C10orf68	Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr6_-_26033796	0.39	ENST00000259791.2	HIST1H2AB	histone cluster 1, H2ab
chr6_+_33239787	0.39	ENST00000439602.2 ENST00000474973.1	RPS18	ribosomal protein S18
chr19_-_47164386	0.39	ENST00000391916.2 ENST00000410105.2	DACT3	dishevelled-binding antagonist of beta-catenin 3
chr8_+_86351056	0.38	ENST00000285381.2	CA3	carbonic anhydrase III, muscle specific
chr6_+_43543942	0.38	ENST00000372226.1 ENST00000443535.1	POLH	polymerase (DNA directed), eta
chr1_-_35658736	0.37	ENST00000357214.5	SFPQ	splicing factor proline/glutamine-rich
chr11_-_61735029	0.37	ENST00000526640.1	FTH1	ferritin, heavy polypeptide 1
chr1_-_54355430	0.36	ENST00000371399.1 ENST00000072644.1 ENST00000412288.1	YIPF1	Yip1 domain family, member 1
chr6_-_133035185	0.36	ENST00000367928.4	VNN1	vanin 1
chr2_-_182545603	0.36	ENST00000295108.3	NEUROD1	neuronal differentiation 1
chr2_+_113763031	0.35	ENST00000259211.6	IL36A	interleukin 36, alpha
chr1_+_224301787	0.35	ENST00000366862.5 ENST00000424254.2	FBXO28	F-box protein 28
chr6_+_46761118	0.34	ENST00000230588.4	MEP1A	meprin A, alpha (PABA peptide hydrolase)
chr15_+_81071684	0.34	ENST00000220244.3 ENST00000394685.3 ENST00000356249.5	KIAA1199	KIAA1199

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	28.2	GO:0045095	keratin filament(GO:0045095)
0.6	4.6	GO:0005610	laminin-5 complex(GO:0005610)
0.4	1.3	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4	20.9	GO:0001533	cornified envelope(GO:0001533)
0.4	2.0	GO:0036128	CatSper complex(GO:0036128)
0.4	1.5	GO:1990745	EARP complex(GO:1990745)
0.3	2.1	GO:1990357	terminal web(GO:1990357)
0.3	2.7	GO:0035976	AP1 complex(GO:0035976)
0.3	2.3	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.3	2.0	GO:0001939	female pronucleus(GO:0001939)
0.3	1.6	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.3	1.1	GO:0070288	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.3	4.8	GO:0097386	glial cell projection(GO:0097386)
0.2	0.7	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.2	16.8	GO:0005882	intermediate filament(GO:0005882)
0.2	1.2	GO:1990037	Lewy body core(GO:1990037)
0.2	2.4	GO:0097470	ribbon synapse(GO:0097470)
0.2	3.9	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	6.6	GO:0009925	basal plasma membrane(GO:0009925)
0.2	4.4	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.2	12.8	GO:0035580	specific granule lumen(GO:0035580)
0.1	7.6	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.1	4.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	1.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.3	GO:0005588	collagen type V trimer(GO:0005588)
0.1	1.5	GO:0030478	actin cap(GO:0030478)
0.1	7.6	GO:0005604	basement membrane(GO:0005604)
0.1	0.5	GO:0030057	desmosome(GO:0030057) paranodal junction(GO:0033010)
0.1	3.2	GO:0002102	podosome(GO:0002102)
0.1	0.5	GO:0005916	fascia adherens(GO:0005916)
0.1	1.5	GO:0031527	filopodium membrane(GO:0031527)
0.0	1.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	2.5	GO:0031430	M band(GO:0031430)
0.0	0.4	GO:0042382	paraspeckles(GO:0042382)
0.0	0.3	GO:0043196	varicosity(GO:0043196)
0.0	5.6	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	6.7	GO:0031901	early endosome membrane(GO:0031901)
0.0	33.1	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	1.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.5	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.5	GO:0036038	MKS complex(GO:0036038)
0.0	1.2	GO:0097546	ciliary base(GO:0097546)
0.0	0.3	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.9	GO:0001650	fibrillar center(GO:0001650)
0.0	0.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	1.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	5.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.5	GO:0005921	gap junction(GO:0005921)
0.0	0.2	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.4	GO:0014704	intercalated disc(GO:0014704)
0.0	0.7	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.3	GO:0000786	nucleosome(GO:0000786)
0.0	6.7	GO:0005925	focal adhesion(GO:0005925)
0.0	1.1	GO:0005814	centriole(GO:0005814)
0.0	0.5	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.5	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.5	GO:0005901	caveola(GO:0005901)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	16.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	8.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.2	4.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	2.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	3.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	5.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	6.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	1.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	3.0	PID ALK1 PATHWAY	ALK1 signaling events
0.1	2.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	2.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	15.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	4.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	2.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	5.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	2.8	PID FOXO PATHWAY	FoxO family signaling
0.1	1.5	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	1.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	2.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	2.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.4	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.3	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.6	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.2	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.5	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.2	ST GAQ PATHWAY	G alpha q Pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	7.4	GO:0009996	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) Wnt signaling pathway involved in somitogenesis(GO:0090244)
1.8	5.3	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.7	10.4	GO:0055064	chloride ion homeostasis(GO:0055064)
1.3	3.9	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.2	33.7	GO:0071294	cellular response to zinc ion(GO:0071294)
1.1	4.6	GO:0006542	glutamine biosynthetic process(GO:0006542)
1.1	5.7	GO:0060356	leucine import(GO:0060356)
1.1	3.3	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.0	6.0	GO:0032119	sequestering of zinc ion(GO:0032119)
0.9	0.9	GO:0045168	cell-cell signaling involved in cell fate commitment(GO:0045168)
0.8	6.5	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.7	2.0	GO:0005988	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.6	1.9	GO:0016095	polyprenol catabolic process(GO:0016095)
0.6	3.1	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.6	1.8	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.6	2.3	GO:0070426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.6	2.8	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.5	0.5	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.5	1.6	GO:0010621	negative regulation of transcription by transcription factor localization(GO:0010621)
0.5	62.0	GO:0070268	cornification(GO:0070268)
0.5	2.9	GO:0038172	interleukin-33-mediated signaling pathway(GO:0038172)
0.5	1.5	GO:0007439	ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.5	2.3	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
0.4	1.3	GO:0060279	negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4	0.4	GO:0043163	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.4	1.3	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.4	1.7	GO:0035425	autocrine signaling(GO:0035425)
0.4	2.1	GO:1902896	terminal web assembly(GO:1902896)
0.4	0.8	GO:0051097	negative regulation of helicase activity(GO:0051097)
0.4	5.7	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.4	2.8	GO:0070294	renal sodium ion absorption(GO:0070294)
0.4	1.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4	4.4	GO:0009414	response to water deprivation(GO:0009414)
0.4	1.2	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.4	6.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.4	2.3	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.3	2.7	GO:0001661	conditioned taste aversion(GO:0001661)
0.3	1.6	GO:0070295	renal water absorption(GO:0070295)
0.3	1.5	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.3	0.8	GO:0006597	spermine biosynthetic process(GO:0006597)
0.3	2.4	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.3	0.3	GO:0060259	positive regulation of behavior(GO:0048520) regulation of feeding behavior(GO:0060259) positive regulation of feeding behavior(GO:2000253)
0.2	3.3	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.2	1.1	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.2	3.0	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.2	0.4	GO:1900155	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2	2.6	GO:0070307	lens fiber cell development(GO:0070307)
0.2	4.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	0.5	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2	0.8	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2	0.5	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.2	0.3	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.2	0.6	GO:1903788	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.2	3.2	GO:0003334	keratinocyte development(GO:0003334)
0.2	1.1	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1	0.6	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.1	4.1	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.1	0.3	GO:0036466	synaptic vesicle recycling via endosome(GO:0036466)
0.1	0.8	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	4.5	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.1	0.5	GO:0042710	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1	0.7	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1	0.4	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.1	0.5	GO:0070384	Harderian gland development(GO:0070384)
0.1	0.5	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1	4.8	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.7	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.5	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1	1.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.3	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.1	0.3	GO:2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1	0.3	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.1	2.2	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.1	0.4	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.1	0.6	GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1	0.7	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.1	0.5	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	1.5	GO:0003351	epithelial cilium movement(GO:0003351)
0.1	0.2	GO:0045471	response to ethanol(GO:0045471)
0.1	0.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.5	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1	0.2	GO:1904438	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1	0.5	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.1	0.3	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	2.4	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.1	0.4	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.7	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.2	GO:2000705	dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1	2.1	GO:0060325	face morphogenesis(GO:0060325)
0.1	0.4	GO:0071494	cellular response to UV-C(GO:0071494)
0.1	0.2	GO:0045112	integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.3	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	0.2	GO:0051037	histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1	0.5	GO:0090022	myeloid progenitor cell differentiation(GO:0002318) regulation of neutrophil chemotaxis(GO:0090022)
0.1	0.2	GO:0014016	neuroblast differentiation(GO:0014016)
0.1	0.2	GO:0044027	hypermethylation of CpG island(GO:0044027)
0.1	1.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.7	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	0.5	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	1.6	GO:0007616	long-term memory(GO:0007616)
0.0	0.3	GO:0033133	fructose 2,6-bisphosphate metabolic process(GO:0006003) positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.3	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0	0.3	GO:0051384	response to glucocorticoid(GO:0051384)
0.0	0.7	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.5	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.1	GO:0002881	negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0	0.4	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.5	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.3	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	1.2	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.1	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.4	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.0	0.2	GO:0036414	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.3	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.3	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	1.5	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	5.4	GO:0043542	endothelial cell migration(GO:0043542)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.2	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.2	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.6	GO:0008285	negative regulation of cell proliferation(GO:0008285)
0.0	1.6	GO:0006342	chromatin silencing(GO:0006342)
0.0	0.4	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.7	GO:0032091	negative regulation of protein binding(GO:0032091)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.4	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.7	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.9	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.3	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.7	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.0	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	11.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
1.5	7.3	GO:0042289	MHC class II protein binding(GO:0042289)
1.1	4.6	GO:0016880	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.7	7.4	GO:0039706	co-receptor binding(GO:0039706)
0.7	2.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.6	10.8	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	5.7	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.5	2.9	GO:0002114	interleukin-33 receptor activity(GO:0002114)
0.5	1.9	GO:0047718	enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.4	1.3	GO:0070699	type II activin receptor binding(GO:0070699)
0.4	1.6	GO:0015254	glycerol channel activity(GO:0015254)
0.4	0.7	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3	2.4	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.3	2.3	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.3	4.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.3	3.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.3	1.9	GO:0070492	oligosaccharide binding(GO:0070492)
0.3	3.6	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	2.0	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	1.3	GO:1990254	keratin filament binding(GO:1990254)
0.2	2.3	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.2	1.0	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.2	0.6	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.2	1.5	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.2	0.7	GO:0004743	pyruvate kinase activity(GO:0004743)
0.2	0.5	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.2	0.5	GO:1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1	1.3	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	5.0	GO:0042056	chemoattractant activity(GO:0042056)
0.1	1.5	GO:0045159	myosin II binding(GO:0045159)
0.1	1.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	2.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	2.8	GO:0017081	chloride channel regulator activity(GO:0017081)
0.1	18.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	0.3	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.3	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1	13.4	GO:0002020	protease binding(GO:0002020)
0.1	0.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	1.6	GO:0070628	proteasome binding(GO:0070628)
0.1	1.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.1	2.7	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	1.0	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	0.5	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	0.4	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	1.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	6.9	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.5	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	3.5	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	0.5	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.8	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.5	GO:0097016	L27 domain binding(GO:0097016)
0.0	4.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.7	GO:0016918	retinal binding(GO:0016918)
0.0	0.3	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.7	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	3.2	GO:0050681	androgen receptor binding(GO:0050681)
0.0	1.3	GO:0005109	frizzled binding(GO:0005109)
0.0	10.3	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.2	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	0.2	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.0	0.1	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
0.0	1.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.3	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.3	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.0	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	28.3	GO:0008270	zinc ion binding(GO:0008270)
0.0	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	2.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	18.3	GO:0005198	structural molecule activity(GO:0005198)
0.0	1.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	1.7	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.0	1.1	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.0	1.2	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.7	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.6	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	4.9	GO:0003924	GTPase activity(GO:0003924)
0.0	0.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	1.6	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	1.5	GO:0019905	syntaxin binding(GO:0019905)
0.0	2.0	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.5	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.5	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.9	GO:0051087	chaperone binding(GO:0051087)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	10.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	4.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	4.6	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.1	2.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1	5.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	2.7	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	4.0	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	1.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	1.8	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	2.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	1.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	2.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	4.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	1.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.8	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	1.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	1.0	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	3.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	1.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.5	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.6	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	2.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)