ISMARA results: TBX1

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ENCODE cell lines, expression (Ernst 2011)

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Results for TBX1

Z-value: 1.57

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Transcription factors associated with TBX1

Gene Symbol	Gene ID	Gene Info
TBX1 Ensembl NCBI GeneCards UniProt	ENSG00000184058.8	TBX1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TBX1	hg19_v2_chr22_+_19744226_19744226	-0.48	6.1e-02	Click!

Activity profile of TBX1 motif

Sorted Z-values of TBX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX1

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr17_-_7080227	3.27	ENST00000574330.1	ASGR1	asialoglycoprotein receptor 1
chr6_-_160166218	3.02	ENST00000537657.1	SOD2	superoxide dismutase 2, mitochondrial
chr14_+_95078714	2.74	ENST00000393078.3 ENST00000393080.4 ENST00000467132.1	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr15_-_79237433	2.67	ENST00000220166.5	CTSH	cathepsin H
chr19_-_9731872	2.46	ENST00000424629.1 ENST00000326044.5 ENST00000354661.4 ENST00000435550.1 ENST00000444611.1 ENST00000421525.1	ZNF561	zinc finger protein 561
chrX_-_133119476	2.37	ENST00000543339.1	GPC3	glypican 3
chr2_+_228678550	2.36	ENST00000409189.3 ENST00000358813.4	CCL20	chemokine (C-C motif) ligand 20
chr17_+_53343577	2.29	ENST00000573945.1	HLF	hepatic leukemia factor
chr12_-_53594227	2.26	ENST00000550743.2	ITGB7	integrin, beta 7
chr2_+_75061108	2.12	ENST00000290573.2	HK2	hexokinase 2
chr10_+_94451574	2.01	ENST00000492654.2	HHEX	hematopoietically expressed homeobox
chr11_-_33913708	2.00	ENST00000257818.2	LMO2	LIM domain only 2 (rhombotin-like 1)
chr2_+_219283815	1.99	ENST00000248444.5 ENST00000454069.1 ENST00000392114.2	VIL1	villin 1
chr21_-_15918618	1.99	ENST00000400564.1 ENST00000400566.1	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr16_-_55866997	1.91	ENST00000360526.3 ENST00000361503.4	CES1	carboxylesterase 1
chr16_+_12058961	1.86	ENST00000053243.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr16_+_12059050	1.85	ENST00000396495.3	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr10_+_114135952	1.85	ENST00000356116.1 ENST00000433418.1 ENST00000354273.4	ACSL5	acyl-CoA synthetase long-chain family member 5
chr20_-_22565101	1.84	ENST00000419308.2	FOXA2	forkhead box A2
chr10_+_114135004	1.80	ENST00000393081.1	ACSL5	acyl-CoA synthetase long-chain family member 5
chr19_-_10450328	1.69	ENST00000160262.5	ICAM3	intercellular adhesion molecule 3
chr12_-_8025499	1.65	ENST00000431042.2	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr4_+_128554081	1.65	ENST00000335251.6 ENST00000296461.5	INTU	inturned planar cell polarity protein
chr2_-_169769787	1.64	ENST00000451987.1	SPC25	SPC25, NDC80 kinetochore complex component
chr19_-_7764281	1.64	ENST00000360067.4	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr7_-_150675372	1.64	ENST00000262186.5	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr15_-_80263506	1.62	ENST00000335661.6	BCL2A1	BCL2-related protein A1
chr1_-_161193349	1.60	ENST00000469730.2 ENST00000463273.1 ENST00000464492.1 ENST00000367990.3 ENST00000470459.2 ENST00000468465.1 ENST00000463812.1	APOA2	apolipoprotein A-II
chr16_+_12059091	1.60	ENST00000562385.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr8_+_56014949	1.60	ENST00000327381.6	XKR4	XK, Kell blood group complex subunit-related family, member 4
chr16_-_88717423	1.60	ENST00000568278.1 ENST00000569359.1 ENST00000567174.1	CYBA	cytochrome b-245, alpha polypeptide
chrX_-_154563889	1.60	ENST00000369449.2 ENST00000321926.4	CLIC2	chloride intracellular channel 2
chrX_-_52260199	1.54	ENST00000375600.1	XAGE1A	X antigen family, member 1A
chr1_-_169555779	1.53	ENST00000367797.3 ENST00000367796.3	F5	coagulation factor V (proaccelerin, labile factor)
chrX_+_49216659	1.47	ENST00000415752.1	GAGE12I	G antigen 12I
chr14_-_106406090	1.46	ENST00000390593.2	IGHV6-1	immunoglobulin heavy variable 6-1
chr17_-_38721711	1.43	ENST00000578085.1 ENST00000246657.2	CCR7	chemokine (C-C motif) receptor 7
chr16_-_88717482	1.43	ENST00000261623.3	CYBA	cytochrome b-245, alpha polypeptide
chr11_+_60223312	1.40	ENST00000532491.1 ENST00000532073.1 ENST00000534668.1 ENST00000528313.1 ENST00000533306.1	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr11_+_60223225	1.39	ENST00000524807.1 ENST00000345732.4	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr12_-_54691668	1.38	ENST00000553198.1	NFE2	nuclear factor, erythroid 2
chr19_+_10397648	1.37	ENST00000340992.4 ENST00000393717.2	ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr11_+_73358594	1.35	ENST00000227214.6 ENST00000398494.4 ENST00000543085.1	PLEKHB1	pleckstrin homology domain containing, family B (evectins) member 1
chr12_+_69742121	1.33	ENST00000261267.2 ENST00000549690.1 ENST00000548839.1	LYZ	lysozyme
chr8_-_124428569	1.32	ENST00000521903.1	ATAD2	ATPase family, AAA domain containing 2
chr3_+_167453493	1.32	ENST00000295777.5 ENST00000472747.2	SERPINI1	serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr20_+_30640004	1.30	ENST00000520553.1 ENST00000518730.1 ENST00000375852.2	HCK	hemopoietic cell kinase
chr8_-_61880248	1.29	ENST00000525556.1	AC022182.3	AC022182.3
chr19_+_45409011	1.29	ENST00000252486.4 ENST00000446996.1 ENST00000434152.1	APOE	apolipoprotein E
chr12_+_32112340	1.29	ENST00000540924.1 ENST00000312561.4	KIAA1551	KIAA1551
chr17_+_80416050	1.27	ENST00000579198.1 ENST00000390006.4 ENST00000580296.1	NARF	nuclear prelamin A recognition factor
chr1_-_24194771	1.27	ENST00000374479.3	FUCA1	fucosidase, alpha-L- 1, tissue
chr4_-_155511887	1.26	ENST00000302053.3 ENST00000403106.3	FGA	fibrinogen alpha chain
chr14_-_106963409	1.21	ENST00000390621.2	IGHV1-45	immunoglobulin heavy variable 1-45
chr5_-_149792295	1.21	ENST00000518797.1 ENST00000524315.1 ENST00000009530.7 ENST00000377795.3	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr2_+_170590321	1.20	ENST00000392647.2	KLHL23	kelch-like family member 23
chr14_-_55658252	1.18	ENST00000395425.2	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chrX_-_70329118	1.17	ENST00000374188.3	IL2RG	interleukin 2 receptor, gamma
chr7_+_99816859	1.16	ENST00000317271.2	PVRIG	poliovirus receptor related immunoglobulin domain containing
chr22_+_23264766	1.16	ENST00000390331.2	IGLC7	immunoglobulin lambda constant 7
chr16_-_55867146	1.15	ENST00000422046.2	CES1	carboxylesterase 1
chr19_+_18284477	1.15	ENST00000407280.3	IFI30	interferon, gamma-inducible protein 30
chr14_-_106174960	1.15	ENST00000390547.2	IGHA1	immunoglobulin heavy constant alpha 1
chr7_-_71801980	1.15	ENST00000329008.5	CALN1	calneuron 1
chr9_-_132805430	1.14	ENST00000446176.2 ENST00000355681.3 ENST00000420781.1	FNBP1	formin binding protein 1
chr2_+_178257372	1.14	ENST00000264167.4 ENST00000409888.1	AGPS	alkylglycerone phosphate synthase
chr14_-_106573756	1.12	ENST00000390601.2	IGHV3-11	immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr21_-_46340884	1.11	ENST00000302347.5 ENST00000517819.1	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_-_61697862	1.10	ENST00000398571.2	USP34	ubiquitin specific peptidase 34
chr14_-_106054659	1.09	ENST00000390539.2	IGHA2	immunoglobulin heavy constant alpha 2 (A2m marker)
chr19_-_39826639	1.09	ENST00000602185.1 ENST00000598034.1 ENST00000601387.1 ENST00000595636.1 ENST00000253054.8 ENST00000594700.1 ENST00000597595.1	GMFG	glia maturation factor, gamma
chr16_+_32077386	1.08	ENST00000354689.6	IGHV3OR16-9	immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr6_+_131894284	1.08	ENST00000368087.3 ENST00000356962.2	ARG1	arginase 1
chr1_-_156786634	1.08	ENST00000392306.2 ENST00000368199.3	SH2D2A	SH2 domain containing 2A
chr14_+_95047725	1.07	ENST00000554760.1 ENST00000554866.1 ENST00000329597.7 ENST00000556775.1	SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr12_-_63328817	1.06	ENST00000228705.6	PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_-_51875894	1.06	ENST00000600427.1 ENST00000595217.1 ENST00000221978.5	NKG7	natural killer cell group 7 sequence
chr1_-_25256368	1.05	ENST00000308873.6	RUNX3	runt-related transcription factor 3
chr4_-_73434498	1.04	ENST00000286657.4	ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr12_+_102513950	1.04	ENST00000378128.3 ENST00000327680.2 ENST00000541394.1 ENST00000543784.1	PARPBP	PARP1 binding protein
chr1_+_116915855	1.04	ENST00000295598.5	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr8_+_81397876	1.03	ENST00000430430.1	ZBTB10	zinc finger and BTB domain containing 10
chr3_-_13461807	1.03	ENST00000254508.5	NUP210	nucleoporin 210kDa
chr16_+_85645007	1.01	ENST00000405402.2	GSE1	Gse1 coiled-coil protein
chr16_+_30212378	1.01	ENST00000569485.1	SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr17_+_76210367	1.01	ENST00000592734.1 ENST00000587746.1	BIRC5	baculoviral IAP repeat containing 5
chr9_+_117085336	0.99	ENST00000259396.8 ENST00000538816.1	ORM1	orosomucoid 1
chr18_+_32556892	0.99	ENST00000591734.1 ENST00000413393.1 ENST00000589180.1 ENST00000587359.1	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr2_+_33701286	0.99	ENST00000403687.3	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_-_49393092	0.99	ENST00000421952.2	DDN	dendrin
chr14_-_55658323	0.99	ENST00000554067.1 ENST00000247191.2	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chrX_+_49363665	0.98	ENST00000381700.6	GAGE1	G antigen 1
chr17_+_53342311	0.98	ENST00000226067.5	HLF	hepatic leukemia factor
chrX_-_131547596	0.95	ENST00000538204.1 ENST00000370849.3	MBNL3	muscleblind-like splicing regulator 3
chr16_+_72088376	0.95	ENST00000570083.1 ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5	HP HPR	haptoglobin haptoglobin-related protein
chr1_+_39456895	0.94	ENST00000432648.3 ENST00000446189.2 ENST00000372984.4	AKIRIN1	akirin 1
chr3_+_121554046	0.93	ENST00000273668.2 ENST00000451944.2	EAF2	ELL associated factor 2
chr21_-_46340770	0.93	ENST00000397854.3	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_+_26158343	0.93	ENST00000377777.4 ENST00000289316.2	HIST1H2BD	histone cluster 1, H2bd
chr14_-_94856987	0.93	ENST00000449399.3 ENST00000404814.4	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr12_+_56473939	0.92	ENST00000450146.2	ERBB3	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr14_+_95047744	0.92	ENST00000553511.1 ENST00000554633.1 ENST00000555681.1 ENST00000554276.1	SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr10_-_23003460	0.92	ENST00000376573.4	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr16_+_29472707	0.92	ENST00000565290.1	SULT1A4	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr14_-_106733624	0.92	ENST00000390610.2	IGHV1-24	immunoglobulin heavy variable 1-24
chr1_-_15911510	0.91	ENST00000375826.3	AGMAT	agmatine ureohydrolase (agmatinase)
chr3_+_4535025	0.90	ENST00000302640.8 ENST00000354582.6 ENST00000423119.2 ENST00000357086.4 ENST00000456211.2	ITPR1	inositol 1,4,5-trisphosphate receptor, type 1
chr17_+_56769924	0.90	ENST00000461271.1 ENST00000583539.1 ENST00000337432.4 ENST00000421782.2	RAD51C	RAD51 paralog C
chr1_+_93544821	0.89	ENST00000370303.4	MTF2	metal response element binding transcription factor 2
chrX_-_131547625	0.89	ENST00000394311.2	MBNL3	muscleblind-like splicing regulator 3
chr17_-_40428359	0.89	ENST00000293328.3	STAT5B	signal transducer and activator of transcription 5B
chr6_-_89827720	0.89	ENST00000452027.2	SRSF12	serine/arginine-rich splicing factor 12
chr3_-_49459878	0.89	ENST00000546031.1 ENST00000458307.2 ENST00000430521.1	AMT	aminomethyltransferase
chr1_-_247335269	0.89	ENST00000543802.2 ENST00000491356.1 ENST00000472531.1 ENST00000340684.6	ZNF124	zinc finger protein 124
chr16_+_3115298	0.88	ENST00000325568.5 ENST00000534507.1	IL32	interleukin 32
chr14_-_94856951	0.87	ENST00000553327.1 ENST00000556955.1 ENST00000557118.1 ENST00000440909.1	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr19_-_48389651	0.87	ENST00000222002.3	SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr19_+_10397621	0.87	ENST00000380770.3	ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr12_-_8025398	0.87	ENST00000535344.1 ENST00000543909.1	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr9_-_123676827	0.86	ENST00000546084.1	TRAF1	TNF receptor-associated factor 1
chr12_-_15104040	0.86	ENST00000541644.1 ENST00000545895.1	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr17_+_80416482	0.86	ENST00000309794.11 ENST00000345415.7 ENST00000457415.3 ENST00000584411.1 ENST00000412079.2 ENST00000577432.1	NARF	nuclear prelamin A recognition factor
chr14_-_94857004	0.86	ENST00000557492.1 ENST00000448921.1 ENST00000437397.1 ENST00000355814.4 ENST00000393088.4	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_-_31620149	0.86	ENST00000435080.1 ENST00000375976.4 ENST00000441054.1	BAG6	BCL2-associated athanogene 6
chr1_-_156786530	0.85	ENST00000368198.3	SH2D2A	SH2 domain containing 2A
chr1_+_93544791	0.85	ENST00000545708.1 ENST00000540243.1 ENST00000370298.4	MTF2	metal response element binding transcription factor 2
chr17_+_25958174	0.85	ENST00000313648.6 ENST00000577392.1 ENST00000584661.1 ENST00000413914.2	LGALS9	lectin, galactoside-binding, soluble, 9
chrX_+_49235708	0.85	ENST00000381725.1	GAGE2B	G antigen 2B
chr19_-_10450287	0.85	ENST00000589261.1 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3	intercellular adhesion molecule 3
chr17_-_5026397	0.85	ENST00000250076.3	ZNF232	zinc finger protein 232
chrX_+_49188094	0.84	ENST00000381751.1	GAGE13	G antigen 13
chr19_-_18366182	0.84	ENST00000355502.3	PDE4C	phosphodiesterase 4C, cAMP-specific
chr1_+_10271674	0.83	ENST00000377086.1	KIF1B	kinesin family member 1B
chr3_-_182880541	0.83	ENST00000470251.1 ENST00000265598.3	LAMP3	lysosomal-associated membrane protein 3
chr1_-_27952741	0.83	ENST00000399173.1	FGR	feline Gardner-Rasheed sarcoma viral oncogene homolog
chr12_+_6554021	0.83	ENST00000266557.3	CD27	CD27 molecule
chr12_-_8025442	0.82	ENST00000340749.5 ENST00000535295.1 ENST00000539234.1	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr1_+_200993071	0.82	ENST00000446333.1 ENST00000458003.1	RP11-168O16.1	RP11-168O16.1
chr1_-_169680745	0.82	ENST00000236147.4	SELL	selectin L
chr19_-_39108568	0.81	ENST00000586296.1	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr17_+_67498538	0.80	ENST00000589647.1	MAP2K6	mitogen-activated protein kinase kinase 6
chr2_+_201994042	0.80	ENST00000417748.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr5_-_34043310	0.80	ENST00000231338.7	C1QTNF3	C1q and tumor necrosis factor related protein 3
chr16_+_28943260	0.80	ENST00000538922.1 ENST00000324662.3 ENST00000567541.1	CD19	CD19 molecule
chr4_+_15779901	0.79	ENST00000226279.3	CD38	CD38 molecule
chr17_-_76836963	0.79	ENST00000312010.6	USP36	ubiquitin specific peptidase 36
chr3_-_49459865	0.79	ENST00000427987.1	AMT	aminomethyltransferase
chr11_+_121322832	0.79	ENST00000260197.7	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr18_+_29671812	0.79	ENST00000261593.3 ENST00000578914.1	RNF138	ring finger protein 138, E3 ubiquitin protein ligase
chr1_+_16090914	0.79	ENST00000441801.2	FBLIM1	filamin binding LIM protein 1
chrX_-_131623982	0.79	ENST00000370844.1	MBNL3	muscleblind-like splicing regulator 3
chr17_-_29648761	0.78	ENST00000247270.3 ENST00000462804.2	EVI2A	ecotropic viral integration site 2A
chr19_-_48673580	0.78	ENST00000427526.2	LIG1	ligase I, DNA, ATP-dependent
chr17_-_34524157	0.78	ENST00000378354.4 ENST00000394484.1	CCL3L3	chemokine (C-C motif) ligand 3-like 3
chr11_-_28129656	0.78	ENST00000263181.6	KIF18A	kinesin family member 18A
chr14_-_106692191	0.77	ENST00000390607.2	IGHV3-21	immunoglobulin heavy variable 3-21
chr22_-_41215328	0.77	ENST00000434185.1 ENST00000435456.2	SLC25A17	solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr17_-_34625719	0.76	ENST00000422211.2 ENST00000542124.1	CCL3L1	chemokine (C-C motif) ligand 3-like 1
chr1_+_179923873	0.76	ENST00000367607.3 ENST00000491495.2	CEP350	centrosomal protein 350kDa
chr11_-_86666427	0.76	ENST00000531380.1	FZD4	frizzled family receptor 4
chr18_+_268148	0.76	ENST00000581677.1	RP11-705O1.8	RP11-705O1.8
chr17_+_4675175	0.76	ENST00000270560.3	TM4SF5	transmembrane 4 L six family member 5
chr20_+_30639991	0.76	ENST00000534862.1 ENST00000538448.1 ENST00000375862.2	HCK	hemopoietic cell kinase
chr8_-_124408652	0.76	ENST00000287394.5	ATAD2	ATPase family, AAA domain containing 2
chr1_+_209929377	0.76	ENST00000400959.3 ENST00000367025.3	TRAF3IP3	TRAF3 interacting protein 3
chr4_-_39367949	0.76	ENST00000503784.1 ENST00000349703.2 ENST00000381897.1	RFC1	replication factor C (activator 1) 1, 145kDa
chr2_+_68592305	0.76	ENST00000234313.7	PLEK	pleckstrin
chr5_+_176513868	0.76	ENST00000292408.4	FGFR4	fibroblast growth factor receptor 4
chr12_+_54892550	0.75	ENST00000545638.2	NCKAP1L	NCK-associated protein 1-like
chr7_+_73623717	0.75	ENST00000344995.5 ENST00000460943.1	LAT2	linker for activation of T cells family, member 2
chr8_+_11534462	0.75	ENST00000528712.1 ENST00000532977.1	GATA4	GATA binding protein 4
chr14_-_21516590	0.75	ENST00000555026.1	NDRG2	NDRG family member 2
chr1_+_32716840	0.75	ENST00000336890.5	LCK	lymphocyte-specific protein tyrosine kinase
chr13_+_50656307	0.75	ENST00000378180.4	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)
chr1_+_244998602	0.75	ENST00000411948.2	COX20	COX20 cytochrome C oxidase assembly factor
chr19_-_55866061	0.74	ENST00000588572.2 ENST00000593184.1 ENST00000589467.1	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr12_-_8025623	0.74	ENST00000542782.1 ENST00000396589.2 ENST00000535266.1 ENST00000542505.1	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr22_-_29138386	0.74	ENST00000544772.1	CHEK2	checkpoint kinase 2
chr2_+_11696464	0.74	ENST00000234142.5	GREB1	growth regulation by estrogen in breast cancer 1
chr2_+_61108650	0.73	ENST00000295025.8	REL	v-rel avian reticuloendotheliosis viral oncogene homolog
chr16_+_12995468	0.73	ENST00000424107.3 ENST00000558583.1 ENST00000558318.1	SHISA9	shisa family member 9
chr20_+_35201993	0.73	ENST00000373872.4	TGIF2	TGFB-induced factor homeobox 2
chr7_-_99569468	0.73	ENST00000419575.1	AZGP1	alpha-2-glycoprotein 1, zinc-binding
chr20_+_35201857	0.73	ENST00000373874.2	TGIF2	TGFB-induced factor homeobox 2
chr3_-_47823298	0.72	ENST00000254480.5	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr14_-_94789663	0.72	ENST00000557225.1 ENST00000341584.3	SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr2_-_40679186	0.72	ENST00000406785.2	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_+_11674213	0.71	ENST00000381486.2	GREB1	growth regulation by estrogen in breast cancer 1
chr22_+_40322595	0.71	ENST00000420971.1 ENST00000544756.1	GRAP2	GRB2-related adaptor protein 2
chr7_+_64126535	0.71	ENST00000344930.3	ZNF107	zinc finger protein 107
chr17_+_18380051	0.70	ENST00000581545.1 ENST00000582333.1 ENST00000328114.6 ENST00000412421.2 ENST00000583322.1 ENST00000584941.1	LGALS9C	lectin, galactoside-binding, soluble, 9C
chr22_+_40322623	0.70	ENST00000399090.2	GRAP2	GRB2-related adaptor protein 2
chr2_+_201994208	0.70	ENST00000440180.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr13_+_50202435	0.70	ENST00000282026.1	ARL11	ADP-ribosylation factor-like 11
chr8_+_6565854	0.70	ENST00000285518.6	AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5
chr1_+_207627697	0.70	ENST00000458541.2	CR2	complement component (3d/Epstein Barr virus) receptor 2
chr6_+_64345698	0.70	ENST00000506783.1 ENST00000481385.2 ENST00000515594.1 ENST00000494284.2 ENST00000262043.3	PHF3	PHD finger protein 3
chr19_-_48752812	0.69	ENST00000359009.4	CARD8	caspase recruitment domain family, member 8
chr5_-_176433350	0.69	ENST00000377227.4 ENST00000377219.2	UIMC1	ubiquitin interaction motif containing 1
chr3_-_120365866	0.69	ENST00000475447.2	HGD	homogentisate 1,2-dioxygenase

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.9	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.3	4.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	4.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	3.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	0.4	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	2.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	2.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	2.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	6.2	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.9	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	2.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.0	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	1.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	3.6	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.6	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.4	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	4.8	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.3	3.8	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.2	3.7	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.9	3.5	GO:0061289	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.8	3.3	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.7	2.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.7	5.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.7	3.4	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6	1.9	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.6	1.8	GO:0060621	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.6	3.6	GO:0030421	defecation(GO:0030421)
0.6	1.7	GO:0061010	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.5	2.1	GO:0014028	notochord formation(GO:0014028)
0.5	2.3	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.4	2.1	GO:1902896	terminal web assembly(GO:1902896)
0.4	1.5	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.4	1.4	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.3	1.4	GO:0034444	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.3	2.0	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3	1.0	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.3	0.9	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.3	0.9	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.3	3.0	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.3	0.8	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3	1.0	GO:1903288	protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.2	0.7	GO:0010652	regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2	2.0	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.2	1.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	4.8	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.2	0.9	GO:0099542	retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2	0.5	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2	1.1	GO:0032571	response to vitamin K(GO:0032571)
0.2	0.6	GO:2000777	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.2	2.3	GO:0035437	maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2	0.6	GO:1904479	cellular response to bile acid(GO:1903413) negative regulation of intestinal absorption(GO:1904479) response to iron ion starvation(GO:1990641)
0.2	2.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2	1.5	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2	0.3	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.2	0.5	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.2	1.5	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1	0.7	GO:0044855	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1	1.9	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	0.4	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	3.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.4	GO:0006788	heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806)
0.1	0.7	GO:0003070	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1	0.4	GO:0006617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1	0.8	GO:0035803	egg coat formation(GO:0035803)
0.1	0.4	GO:1903570	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1	0.4	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	2.7	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1	0.7	GO:0046208	spermine catabolic process(GO:0046208)
0.1	0.6	GO:0048478	replication fork protection(GO:0048478)
0.1	0.5	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1	2.5	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	1.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.8	GO:0001767	establishment of lymphocyte polarity(GO:0001767)
0.1	0.3	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.1	0.5	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1	0.1	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1	0.2	GO:0060300	regulation of cytokine activity(GO:0060300)
0.1	0.6	GO:0021730	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1	0.2	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	1.1	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	0.3	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	1.8	GO:0006907	pinocytosis(GO:0006907)
0.1	1.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.8	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.1	0.6	GO:0051414	response to cortisol(GO:0051414)
0.1	0.2	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1	0.3	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	1.3	GO:0016264	gap junction assembly(GO:0016264)
0.1	2.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.2	GO:0061386	closure of optic fissure(GO:0061386)
0.1	0.8	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1	3.7	GO:0021545	cranial nerve development(GO:0021545)
0.1	0.8	GO:2000194	regulation of female gonad development(GO:2000194)
0.1	0.3	GO:0051582	peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.6	GO:2000210	positive regulation of anoikis(GO:2000210)
0.1	0.4	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.2	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.1	2.0	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.9	GO:0002021	response to dietary excess(GO:0002021)
0.0	1.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.2	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.3	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.0	0.7	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0090035	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0	0.5	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.7	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050) positive regulation of female receptivity(GO:0045925)
0.0	0.2	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.0	0.1	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0	0.1	GO:0043012	regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0	0.4	GO:0002911	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0	0.3	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	1.6	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0	1.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	2.1	GO:0007566	embryo implantation(GO:0007566)
0.0	2.6	GO:0007602	phototransduction(GO:0007602)
0.0	0.5	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	1.3	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	1.4	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.9	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.2	GO:0090131	mesenchyme migration(GO:0090131)
0.0	0.2	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.4	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0	0.2	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0	0.6	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0060969	negative regulation of gene silencing(GO:0060969)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:0060579	ventral spinal cord interneuron specification(GO:0021521) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.1	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0	0.4	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.1	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.1	GO:0039003	pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) metanephric nephron tubule formation(GO:0072289) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0	0.8	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.4	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.2	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.5	GO:0032967	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0	0.2	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.0	GO:0002384	hepatic immune response(GO:0002384)
0.0	0.1	GO:1903433	regulation of constitutive secretory pathway(GO:1903433)
0.0	0.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.9	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	1.0	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.4	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.0	GO:0038060	nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0	0.1	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.1	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0043383	negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0	0.1	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0	0.0	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0046136	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3	1.3	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3	1.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	2.2	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2	1.0	GO:0097527	Fas signaling pathway(GO:0036337) necroptotic signaling pathway(GO:0097527)
0.1	1.8	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.9	GO:0035803	egg coat formation(GO:0035803)
0.1	0.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1	0.9	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1	0.3	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	0.5	GO:0051414	response to cortisol(GO:0051414)
0.1	0.7	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
0.1	1.8	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0	0.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.0	0.2	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)
0.0	0.1	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0	0.2	GO:0009441	glycolate metabolic process(GO:0009441)
0.0	0.2	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0	0.1	GO:1905068	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0	0.1	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.7	GO:0010107	potassium ion import(GO:0010107)
0.0	0.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.0	0.1	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.3	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.8	3.4	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.8	3.3	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.8	3.9	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.6	5.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.5	1.5	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.5	2.5	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.4	1.8	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.4	1.8	GO:0005046	KDEL sequence binding(GO:0005046)
0.4	1.3	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4	2.3	GO:0003796	lysozyme activity(GO:0003796)
0.3	0.6	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.2	0.7	GO:0052895	norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.2	0.7	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2	3.0	GO:0038132	neuregulin binding(GO:0038132)
0.2	3.0	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.2	4.1	GO:0051787	misfolded protein binding(GO:0051787)
0.2	3.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.2	1.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.2	1.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	0.5	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.2	0.9	GO:0016657	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1	0.7	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1	0.4	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	1.3	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.4	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	1.9	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	1.7	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	1.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	0.3	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1	0.6	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	5.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.6	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	1.9	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1	0.8	GO:0032190	acrosin binding(GO:0032190)
0.1	0.3	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.1	0.8	GO:0046790	virion binding(GO:0046790)
0.1	0.4	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	0.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.7	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.3	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.1	1.3	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	1.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.6	GO:0036310	annealing helicase activity(GO:0036310)
0.1	1.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.4	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	1.5	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.7	GO:0045159	myosin II binding(GO:0045159)
0.1	1.7	GO:0030371	translation repressor activity(GO:0030371)
0.1	5.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.8	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.6	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.1	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0	1.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.8	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.2	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.2	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.0	0.1	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.7	GO:0001968	fibronectin binding(GO:0001968)
0.0	1.3	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	0.8	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	1.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	4.9	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.3	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	1.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	2.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	2.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.0	1.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.3	GO:0070628	proteasome binding(GO:0070628)
0.0	0.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.2	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.3	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.7	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.7	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.4	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.9	GO:0005507	copper ion binding(GO:0005507)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.9	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.8	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	1.1	GO:0016209	antioxidant activity(GO:0016209)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.9	GO:0031625	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)
0.0	1.6	GO:0020037	heme binding(GO:0020037)
0.0	0.0	GO:0004915	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	0.1	GO:0019798	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0	0.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.0	0.4	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.3	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)

Gene overrepresentation in C2:CP:REACTOME category:

Total log-likelihood	Term	Description
1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
1.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
1.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID ARF 3PATHWAY	Arf1 pathway
0.1	2.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	2.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	2.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	2.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	5.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	4.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.1	1.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	3.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	2.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.5	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	2.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	2.0	PID BMP PATHWAY	BMP receptor signaling
0.0	4.1	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.4	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.3	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	1.9	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.9	PID FOXO PATHWAY	FoxO family signaling
0.0	1.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	2.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	4.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.6	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.7	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID MYC PATHWAY	C-MYC pathway

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	10.7	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	3.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	3.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	5.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	2.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.9	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	3.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	4.4	PID AURORA A PATHWAY	Aurora A signaling
0.1	4.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	1.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	3.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	1.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	3.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	3.2	PID FOXO PATHWAY	FoxO family signaling
0.0	3.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	2.2	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.8	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	1.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.0	PID ATM PATHWAY	ATM pathway
0.0	2.4	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.8	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.4	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.5	PID E2F PATHWAY	E2F transcription factor network
0.0	0.8	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	1.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.5	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.6	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.9	PID ATR PATHWAY	ATR signaling pathway
0.0	2.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	1.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.3	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.6	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.5	PID FGF PATHWAY	FGF signaling pathway
0.0	0.4	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.4	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.2	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0000235	astral microtubule(GO:0000235) aster(GO:0005818)
0.1	1.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0061617	MICOS complex(GO:0061617)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	0.1	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.0	1.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.8	GO:0005901	caveola(GO:0005901)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.4	5.9	GO:0005916	fascia adherens(GO:0005916)
0.4	1.4	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.3	3.8	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.2	2.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	0.5	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	1.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.2	5.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.2	1.0	GO:1990357	terminal web(GO:1990357)
0.2	0.9	GO:1902560	GMP reductase complex(GO:1902560)
0.1	0.9	GO:0043196	varicosity(GO:0043196)
0.1	0.8	GO:0071203	WASH complex(GO:0071203)
0.1	1.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	2.0	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	1.7	GO:0032433	filopodium tip(GO:0032433)
0.1	1.1	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.1	1.3	GO:0005922	connexon complex(GO:0005922)
0.1	0.5	GO:0036021	endolysosome lumen(GO:0036021)
0.1	1.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.6	GO:0045179	apical cortex(GO:0045179)
0.1	2.6	GO:0000421	autophagosome membrane(GO:0000421)
0.1	0.5	GO:0035976	AP1 complex(GO:0035976)
0.1	7.6	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	0.3	GO:0031501	mannosyltransferase complex(GO:0031501)
0.1	0.5	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.1	0.6	GO:0072687	meiotic spindle(GO:0072687)
0.1	0.8	GO:0031209	SCAR complex(GO:0031209)
0.1	0.1	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	1.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.7	GO:0030478	actin cap(GO:0030478)
0.0	0.4	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.3	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	0.2	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.2	GO:0042643	actomyosin, actin portion(GO:0042643)
0.0	0.2	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	0.2	GO:0000836	Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.6	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.4	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	1.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	1.7	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	7.7	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	2.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.6	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	1.8	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.1	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	3.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	1.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.8	GO:0001533	cornified envelope(GO:0001533)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.8	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	2.4	GO:0030018	Z disc(GO:0030018)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	4.3	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.7	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.9	4.4	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.8	2.4	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.7	2.1	GO:0002522	leukocyte migration involved in immune response(GO:0002522)
0.7	2.0	GO:0061010	negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.6	3.1	GO:1902896	terminal web assembly(GO:1902896)
0.6	1.8	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6	3.0	GO:0001315	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.6	2.4	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.6	2.3	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5	1.6	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.5	1.6	GO:0060621	regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.5	1.4	GO:2000525	dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.4	1.8	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4	1.3	GO:0043132	FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350) NAD transport(GO:0043132)
0.4	1.3	GO:1902994	regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995)
0.4	2.0	GO:0061107	seminal vesicle development(GO:0061107)
0.4	2.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.4	1.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.4	1.5	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.4	2.2	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.4	1.1	GO:1902023	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.3	1.4	GO:0014028	notochord formation(GO:0014028)
0.3	1.7	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3	1.6	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.3	1.3	GO:0016139	glycoside catabolic process(GO:0016139)
0.3	0.9	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3	3.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.3	1.5	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.3	2.1	GO:1904925	negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3	0.6	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.3	1.5	GO:0032571	response to vitamin K(GO:0032571)
0.3	1.7	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.3	1.4	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.3	0.8	GO:1904647	response to rotenone(GO:1904647)
0.3	0.8	GO:0072709	cellular response to sorbitol(GO:0072709)
0.3	1.3	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.3	0.8	GO:1902771	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3	1.3	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3	1.3	GO:1903412	response to bile acid(GO:1903412)
0.3	1.0	GO:1901162	primary amino compound biosynthetic process(GO:1901162)
0.3	2.5	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.3	0.8	GO:0003285	septum secundum development(GO:0003285)
0.2	0.7	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2	1.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	0.7	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.2	0.9	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.2	2.2	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.2	0.7	GO:1901355	response to rapamycin(GO:1901355)
0.2	1.1	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.2	0.7	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2	0.9	GO:0071461	cellular response to redox state(GO:0071461)
0.2	0.9	GO:1904379	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2	2.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	0.6	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.2	1.2	GO:0070560	protein secretion by platelet(GO:0070560)
0.2	1.0	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.2	4.8	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2	0.8	GO:0048859	formation of anatomical boundary(GO:0048859)
0.2	0.6	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2	0.6	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2	0.6	GO:1903939	negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.2	0.8	GO:0035426	extracellular matrix-cell signaling(GO:0035426) retinal blood vessel morphogenesis(GO:0061304)
0.2	1.0	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	0.2	GO:0036115	fatty-acyl-CoA catabolic process(GO:0036115)
0.2	0.4	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.2	0.5	GO:0051086	chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2	0.9	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
0.2	1.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2	0.5	GO:0045082	interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2	0.5	GO:0016095	polyprenol catabolic process(GO:0016095)
0.2	1.0	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2	1.0	GO:1903416	response to glycoside(GO:1903416)
0.2	0.7	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.2	0.5	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2	0.3	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2	0.5	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.2	0.5	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.2	1.2	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.2	1.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.5	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2	0.5	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.2	0.6	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2	0.5	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2	0.5	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.2	4.2	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.2	1.5	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.6	GO:0022614	membrane to membrane docking(GO:0022614) establishment of Sertoli cell barrier(GO:0097368)
0.1	0.3	GO:1904468	negative regulation of tumor necrosis factor secretion(GO:1904468)
0.1	2.4	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1	2.7	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.4	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.4	GO:0043449	cellular alkene metabolic process(GO:0043449)
0.1	0.6	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1	1.0	GO:2000252	negative regulation of feeding behavior(GO:2000252)
0.1	1.0	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.1	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.1	0.4	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.1	1.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	2.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	2.7	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.3	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1	0.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	2.2	GO:0033005	positive regulation of mast cell activation(GO:0033005)
0.1	3.0	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1	0.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.9	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.1	0.4	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1	2.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	2.3	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	1.0	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	0.4	GO:0097254	renal tubular secretion(GO:0097254)
0.1	0.6	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1	0.4	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1	3.1	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	0.2	GO:0019827	stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.1	0.4	GO:0032292	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.4	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.1	0.4	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.1	0.4	GO:0060370	susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1	0.3	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.1	0.7	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.8	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.1	0.5	GO:0051958	methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1	2.4	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1	0.5	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.1	0.3	GO:1990519	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1	0.6	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.1	0.4	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	2.6	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.3	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.1	0.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	7.4	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	1.1	GO:0070673	response to interleukin-18(GO:0070673)
0.1	1.5	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1	0.3	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.6	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.9	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1	0.5	GO:0036100	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1	0.3	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.6	GO:0071395	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1	0.2	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904) regulation of pro-B cell differentiation(GO:2000973)
0.1	0.2	GO:0003383	apical constriction(GO:0003383)
0.1	0.5	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.6	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.1	0.7	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.4	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1	0.6	GO:0030421	defecation(GO:0030421)
0.1	0.4	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	0.2	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.1	0.7	GO:1903232	melanosome assembly(GO:1903232)
0.1	0.4	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	0.7	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.8	GO:0071313	cellular response to caffeine(GO:0071313)
0.1	0.6	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	1.0	GO:0007422	peripheral nervous system development(GO:0007422)
0.1	0.3	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.2	GO:0090135	actin filament branching(GO:0090135)
0.1	0.9	GO:0033198	response to ATP(GO:0033198)
0.1	0.3	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1	0.8	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.4	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.3	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.3	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.1	1.2	GO:0033623	regulation of integrin activation(GO:0033623)
0.1	0.5	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.1	0.6	GO:0071315	cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.1	0.3	GO:1904303	positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) positive regulation of leukocyte tethering or rolling(GO:1903238) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1	1.1	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.1	5.5	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.1	0.3	GO:1904693	midbrain morphogenesis(GO:1904693)
0.1	0.3	GO:0010585	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1	1.6	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.3	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1	0.3	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	1.4	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.1	0.3	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.1	1.3	GO:0032875	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.1	0.3	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.1	0.2	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.1	0.7	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.3	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.1	0.2	GO:1903033	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1	0.5	GO:0090116	C-5 methylation of cytosine(GO:0090116)
0.1	0.7	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.4	GO:0033274	response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1	0.6	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	1.3	GO:0038092	nodal signaling pathway(GO:0038092)
0.1	0.2	GO:0051899	membrane depolarization(GO:0051899)
0.1	0.3	GO:0042126	nitrate metabolic process(GO:0042126)
0.1	0.4	GO:0048599	oocyte development(GO:0048599)
0.1	0.7	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1	0.9	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	1.1	GO:0016075	rRNA catabolic process(GO:0016075)
0.1	0.2	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1	1.0	GO:0016180	snRNA processing(GO:0016180)
0.1	0.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.6	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.1	0.5	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.1	1.6	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.1	0.2	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1	0.9	GO:0072520	seminiferous tubule development(GO:0072520)
0.1	4.1	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.1	1.4	GO:0071420	cellular response to histamine(GO:0071420)
0.1	1.5	GO:0008053	mitochondrial fusion(GO:0008053)
0.1	1.0	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1	3.0	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.1	0.3	GO:0035711	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426) regulation of nucleotide-excision repair(GO:2000819)
0.1	0.3	GO:0050711	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 secretion(GO:0050711) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1	0.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.7	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.5	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.1	0.5	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.4	GO:1905031	regulation of potassium ion export(GO:1902302) regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
0.1	0.5	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.8	GO:0043102	amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.1	0.3	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.4	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.1	0.5	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.3	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:1990637	response to prolactin(GO:1990637)
0.1	0.4	GO:1990774	tumor necrosis factor secretion(GO:1990774)
0.1	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	1.4	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.9	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.2	GO:1990502	dense core granule maturation(GO:1990502)
0.1	0.2	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.2	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.1	0.4	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.4	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.1	0.4	GO:0033504	floor plate development(GO:0033504)
0.1	0.6	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.2	GO:0090034	regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1	0.3	GO:0048852	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
0.1	1.0	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.3	GO:1902775	mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1	0.5	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	0.8	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1	0.3	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1	1.2	GO:0051923	sulfation(GO:0051923)
0.1	0.6	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1	0.5	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1	0.2	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1	1.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.1	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.1	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.4	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	0.5	GO:0006999	nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292)
0.1	0.9	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.1	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.2	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.1	0.4	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.6	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.2	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1	0.4	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.5	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.1	0.4	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1	0.9	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	1.3	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.1	0.2	GO:0008300	isoprenoid catabolic process(GO:0008300) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.5	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0050951	detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.0	0.3	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.3	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.4	GO:0042364	water-soluble vitamin biosynthetic process(GO:0042364)
0.0	0.1	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.1	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.0	0.5	GO:0015871	choline transport(GO:0015871)
0.0	0.9	GO:0006584	catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0	1.3	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.6	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.1	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.0	0.1	GO:0060844	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0	0.3	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.4	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0051167	xylulose metabolic process(GO:0005997) glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.2	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.6	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.2	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	1.8	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.6	GO:1903358	regulation of Golgi organization(GO:1903358)
0.0	0.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.4	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.0	0.3	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.0	0.5	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	1.0	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.7	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.2	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0006711	estrogen catabolic process(GO:0006711)
0.0	0.3	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.2	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.3	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	1.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.5	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.0	0.2	GO:0090278	negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0	1.6	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.0	0.1	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.0	0.6	GO:0036148	phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0	0.2	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.4	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.2	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	1.2	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.9	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.9	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.3	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.1	GO:0044268	angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.3	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.6	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.2	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.9	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0	0.3	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.3	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.0	0.6	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.0	GO:0042222	interleukin-1 biosynthetic process(GO:0042222)
0.0	0.1	GO:0042636	negative regulation of hair cycle(GO:0042636)
0.0	0.6	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)
0.0	0.2	GO:0046520	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0	0.4	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.0	0.1	GO:0002188	formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188)
0.0	0.2	GO:0015692	lead ion transport(GO:0015692)
0.0	0.9	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.2	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.2	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.0	0.3	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.3	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.2	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.2	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.2	GO:2000254	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.1	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.9	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.3	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0	0.3	GO:0035247	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.3	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.7	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.4	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.2	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.4	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.3	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.2	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.0	0.8	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.4	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0	0.1	GO:0019417	sulfur oxidation(GO:0019417)
0.0	0.4	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.7	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.3	GO:0033622	integrin activation(GO:0033622)
0.0	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0050893	sensory processing(GO:0050893)
0.0	0.0	GO:0070243	regulation of thymocyte apoptotic process(GO:0070243)
0.0	0.7	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.4	GO:0045475	locomotor rhythm(GO:0045475)
0.0	1.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.4	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	2.3	GO:0006334	nucleosome assembly(GO:0006334)
0.0	1.7	GO:0007602	phototransduction(GO:0007602)
0.0	0.4	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.7	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.6	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.3	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.5	GO:0097186	amelogenesis(GO:0097186)
0.0	0.3	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	1.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.4	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.2	GO:0061365	positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0	0.1	GO:0060423	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.1	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0003085	negative regulation of systemic arterial blood pressure(GO:0003085)
0.0	0.5	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.3	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.2	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.8	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.0	GO:1903826	arginine transmembrane transport(GO:1903826)
0.0	1.8	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.3	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.9	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.4	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.2	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.3	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.1	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.1	GO:0071027	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	0.3	GO:0022401	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0	0.1	GO:0014827	intestine smooth muscle contraction(GO:0014827)
0.0	0.1	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.3	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.2	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.1	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.2	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.1	GO:0044070	regulation of anion transport(GO:0044070)
0.0	1.6	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	1.6	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0030279	negative regulation of ossification(GO:0030279)
0.0	0.3	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	0.4	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.4	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.2	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.4	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	0.2	GO:0097369	sodium ion import(GO:0097369)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:2001225	regulation of chloride transport(GO:2001225)
0.0	1.1	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.1	GO:1902416	regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416) regulation of RNA binding(GO:1905214) positive regulation of RNA binding(GO:1905216)
0.0	0.2	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.2	GO:0051321	meiotic cell cycle(GO:0051321)
0.0	0.2	GO:0071353	response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0	0.2	GO:0050728	negative regulation of inflammatory response(GO:0050728)
0.0	0.6	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.6	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0048290	isotype switching to IgA isotypes(GO:0048290)
0.0	0.3	GO:0016236	macroautophagy(GO:0016236)
0.0	0.2	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	0.7	GO:0006953	acute-phase response(GO:0006953)
0.0	0.5	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.4	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.5	GO:0051225	spindle assembly(GO:0051225)
0.0	0.5	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.2	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.1	GO:0006740	NADPH regeneration(GO:0006740)
0.0	1.0	GO:0070126	mitochondrial translational elongation(GO:0070125) mitochondrial translational termination(GO:0070126)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.1	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.6	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0	0.3	GO:0060711	labyrinthine layer development(GO:0060711)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	1.0	GO:0007286	spermatid development(GO:0007286)
0.0	0.4	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.3	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.0	0.2	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.6	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.6	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.1	GO:0045143	homologous chromosome segregation(GO:0045143)
0.0	1.5	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.7	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.2	GO:0009948	anterior/posterior axis specification(GO:0009948)
0.0	0.0	GO:0099624	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.0	0.5	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	0.3	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.4	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.3	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.1	GO:0051591	response to cAMP(GO:0051591)
0.0	0.2	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0072503	cellular divalent inorganic cation homeostasis(GO:0072503) divalent inorganic cation homeostasis(GO:0072507)
0.0	0.0	GO:0098905	regulation of bundle of His cell action potential(GO:0098905) regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.0	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.0	0.1	GO:0006633	fatty acid biosynthetic process(GO:0006633)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.1	0.4	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.1	0.3	GO:0004137	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1	1.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.9	GO:0032190	acrosin binding(GO:0032190)
0.1	2.2	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.2	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	5.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.9	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.8	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.0	0.1	GO:0045174	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	1.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0071745	IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.7	2.0	GO:0097182	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.6	2.3	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.5	1.6	GO:0031262	Ndc80 complex(GO:0031262)
0.5	2.6	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.5	3.8	GO:0097208	alveolar lamellar body(GO:0097208)
0.4	1.3	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.4	1.8	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.3	1.7	GO:0005927	muscle tendon junction(GO:0005927)
0.3	2.3	GO:0005638	lamin filament(GO:0005638)
0.3	4.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.2	0.9	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.2	0.9	GO:0071001	U4/U6 snRNP(GO:0071001)
0.2	1.7	GO:0032133	chromosome passenger complex(GO:0032133)
0.2	0.9	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2	0.6	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.2	1.1	GO:1990357	terminal web(GO:1990357)
0.2	2.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.2	1.2	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	0.7	GO:0044611	nuclear pore inner ring(GO:0044611)
0.2	8.0	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	2.1	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.6	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.3	GO:0098839	postsynaptic density membrane(GO:0098839)
0.1	0.5	GO:0000811	GINS complex(GO:0000811)
0.1	0.8	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	0.9	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	0.9	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.4	GO:0097447	dendritic tree(GO:0097447)
0.1	2.3	GO:0032433	filopodium tip(GO:0032433)
0.1	1.9	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	1.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.1	GO:0005827	polar microtubule(GO:0005827)
0.1	2.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.7	GO:0030061	mitochondrial crista(GO:0030061)
0.1	1.4	GO:0031209	SCAR complex(GO:0031209)
0.1	0.4	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1	1.3	GO:0042555	MCM complex(GO:0042555)
0.1	0.8	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	2.1	GO:0042627	chylomicron(GO:0042627)
0.1	3.1	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.5	GO:1990393	3M complex(GO:1990393)
0.1	0.5	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.7	GO:0045179	apical cortex(GO:0045179)
0.1	0.6	GO:0005844	polysome(GO:0005844)
0.1	0.7	GO:0031931	TORC1 complex(GO:0031931)
0.1	2.1	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	0.8	GO:0032039	integrator complex(GO:0032039)
0.1	0.4	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1	0.7	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.1	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.4	GO:0032021	NELF complex(GO:0032021)
0.1	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.1	1.6	GO:0000242	pericentriolar material(GO:0000242)
0.1	1.8	GO:0035371	microtubule plus-end(GO:0035371)
0.1	1.2	GO:0001741	XY body(GO:0001741)
0.1	1.5	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.4	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	0.3	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.1	0.6	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.8	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	8.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	0.4	GO:0032311	angiogenin-PRI complex(GO:0032311)
0.1	0.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.1	1.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	0.7	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.9	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	0.6	GO:0016013	syntrophin complex(GO:0016013)
0.1	0.7	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.6	GO:0000800	lateral element(GO:0000800)
0.1	0.5	GO:0070652	HAUS complex(GO:0070652)
0.1	0.6	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.7	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.1	0.3	GO:0098843	postsynaptic endocytic zone(GO:0098843)
0.1	0.6	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	1.8	GO:0030673	axolemma(GO:0030673)
0.1	0.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.4	GO:0031415	NatA complex(GO:0031415)
0.1	0.2	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.4	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	1.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.6	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.4	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.2	GO:0031213	RSF complex(GO:0031213)
0.1	0.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.5	GO:0000796	condensin complex(GO:0000796)
0.1	2.5	GO:0005871	kinesin complex(GO:0005871)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.5	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	1.5	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	1.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.7	GO:0097227	sperm annulus(GO:0097227)
0.0	0.2	GO:0005655	nucleolar ribonuclease P complex(GO:0005655)
0.0	0.1	GO:0000793	condensed chromosome(GO:0000793)
0.0	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.6	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.8	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.3	GO:0032389	MutLalpha complex(GO:0032389)
0.0	1.0	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	2.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.8	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	1.4	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	2.2	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.3	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.3	GO:0005840	ribosome(GO:0005840)
0.0	1.4	GO:0044815	nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0	0.6	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	3.3	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	2.1	GO:0015030	Cajal body(GO:0015030)
0.0	0.2	GO:0070826	paraferritin complex(GO:0070826)
0.0	0.6	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.5	GO:0005922	connexon complex(GO:0005922)
0.0	0.5	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.4	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.4	GO:0044754	autolysosome(GO:0044754)
0.0	5.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.1	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.0	0.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.0	0.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	1.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.0	GO:0071020	post-spliceosomal complex(GO:0071020)
0.0	4.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	1.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	3.2	GO:0043204	perikaryon(GO:0043204)
0.0	1.0	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.7	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.4	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.6	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0009368	endopeptidase Clp complex(GO:0009368)
0.0	1.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.3	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	0.4	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	7.3	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	1.4	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0060091	kinocilium(GO:0060091)
0.0	0.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.5	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.0	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0	0.5	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.3	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0034709	methylosome(GO:0034709)
0.0	1.3	GO:0000775	chromosome, centromeric region(GO:0000775)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.4	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.6	3.2	GO:0004771	sterol esterase activity(GO:0004771)
0.6	2.4	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.6	2.8	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.5	4.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.4	1.3	GO:0051185	FAD transmembrane transporter activity(GO:0015230) coenzyme transporter activity(GO:0051185)
0.4	1.3	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.4	1.7	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.4	1.6	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.4	1.2	GO:0004913	interleukin-4 receptor activity(GO:0004913)
0.4	1.1	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.4	1.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3	3.0	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3	0.9	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	2.0	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.3	3.7	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.3	2.6	GO:0070324	thyroid hormone binding(GO:0070324)
0.3	0.8	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.2	4.5	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.2	1.2	GO:0042289	MHC class II protein binding(GO:0042289)
0.2	0.7	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2	1.4	GO:0042610	CD8 receptor binding(GO:0042610)
0.2	1.3	GO:0003796	lysozyme activity(GO:0003796)
0.2	4.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	0.6	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2	0.6	GO:0008859	exoribonuclease II activity(GO:0008859)
0.2	0.8	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.2	1.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	0.6	GO:0047086	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.2	0.6	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.2	10.2	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.2	1.6	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2	2.0	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.2	0.9	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.2	1.5	GO:0019863	IgE binding(GO:0019863)
0.2	0.5	GO:0052870	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2	1.0	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.2	0.5	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.2	0.8	GO:0043208	glycosphingolipid binding(GO:0043208)
0.2	1.1	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	0.5	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.2	0.6	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.2	0.9	GO:0030492	hemoglobin binding(GO:0030492)
0.2	0.5	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2	2.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.4	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	1.7	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.6	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.1	0.5	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.9	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	1.1	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1	0.5	GO:0047718	indanol dehydrogenase activity(GO:0047718)
0.1	0.5	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.1	2.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.7	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.8	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.4	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.4	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.1	0.9	GO:0050733	RS domain binding(GO:0050733)
0.1	0.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.9	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	0.9	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.4	GO:0003883	CTP synthase activity(GO:0003883)
0.1	0.5	GO:0032810	sterol response element binding(GO:0032810)
0.1	0.4	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1	0.4	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	0.6	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.1	0.5	GO:0008518	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1	0.3	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1	0.3	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.1	0.9	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.8	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.3	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.1	0.3	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.1	2.0	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	1.0	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.1	2.5	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0035473	lipase binding(GO:0035473)
0.1	0.3	GO:0004796	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1	0.5	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.6	GO:0001851	complement component C3b binding(GO:0001851)
0.1	0.4	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.1	0.3	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.1	2.3	GO:0071837	HMG box domain binding(GO:0071837)
0.1	1.5	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.3	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.2	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	0.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.1	GO:0001855	complement component C4b binding(GO:0001855)
0.1	0.9	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.6	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.5	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	0.1	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1	0.6	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.1	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.3	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	2.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	0.9	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.5	GO:0015185	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1	1.6	GO:0051400	BH domain binding(GO:0051400)
0.1	0.9	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	2.0	GO:0071949	FAD binding(GO:0071949)
0.1	0.6	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	0.3	GO:0016936	galactoside binding(GO:0016936)
0.1	0.2	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.1	1.1	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	0.3	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1	0.5	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.6	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	0.4	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	0.3	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	0.5	GO:0043199	sulfate binding(GO:0043199)
0.1	0.8	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.6	GO:0000405	bubble DNA binding(GO:0000405)
0.1	2.8	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.1	4.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	1.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.4	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.3	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.1	0.3	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.1	1.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.3	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.1	1.9	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.4	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.9	GO:0038132	neuregulin binding(GO:0038132)
0.1	1.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	0.3	GO:0070051	fibrinogen binding(GO:0070051)
0.1	0.9	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	1.1	GO:0031996	thioesterase binding(GO:0031996)
0.1	1.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.2	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.3	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.6	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.3	GO:0050436	microfibril binding(GO:0050436)
0.1	0.4	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.4	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.8	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.1	0.5	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	1.4	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.1	0.8	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.1	1.5	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.5	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.3	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.1	0.2	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.6	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.1	0.4	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.8	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.1	0.3	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1	0.2	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.1	2.7	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.1	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.8	GO:0031005	filamin binding(GO:0031005)
0.1	0.3	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	1.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.3	GO:0015056	corticotrophin-releasing factor receptor activity(GO:0015056)
0.1	1.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.1	0.2	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	1.3	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	1.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.0	0.6	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.7	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.2	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0	0.3	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	1.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.5	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.3	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	2.0	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.4	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:0043295	glutathione binding(GO:0043295)
0.0	1.3	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	1.8	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.0	1.0	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.5	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.4	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	1.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0004906	interferon-gamma receptor activity(GO:0004906)
0.0	3.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0005549	odorant binding(GO:0005549)
0.0	0.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.6	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.3	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.2	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.6	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0	0.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.4	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.3	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.6	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.4	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	1.0	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.4	GO:0097016	L27 domain binding(GO:0097016)
0.0	1.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0	0.6	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.2	GO:0015087	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0	0.2	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.0	0.1	GO:0033878	hormone-sensitive lipase activity(GO:0033878)
0.0	0.4	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.7	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.4	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	1.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.3	GO:0035242	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.0	0.1	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	1.9	GO:0035064	methylated histone binding(GO:0035064)
0.0	3.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	2.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	1.3	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.8	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.3	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.3	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	1.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	1.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0098505	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	1.7	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.1	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0004979	beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0	0.2	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	1.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.5	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.7	GO:0004540	ribonuclease activity(GO:0004540)
0.0	0.6	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.2	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.2	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.6	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0031489	myosin V binding(GO:0031489)
0.0	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.5	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	1.7	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.3	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.7	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	1.3	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.7	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.1	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0000150	recombinase activity(GO:0000150)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.7	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0	0.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.3	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.0	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	1.9	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0	0.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.5	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.4	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.1	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.0	GO:0050135	NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0	0.1	GO:0017018	myosin phosphatase activity(GO:0017018)
0.0	0.3	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.2	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0	0.2	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.3	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.1	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	0.5	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.2	4.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	3.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	7.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	1.9	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	2.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.9	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	2.9	REACTOME KINESINS	Genes involved in Kinesins
0.1	0.8	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.4	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	8.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	3.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	2.8	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.1	4.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	1.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	2.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	2.1	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	1.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	2.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	1.2	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.1	5.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	1.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1	1.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.0	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	1.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	2.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.4	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	1.4	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.8	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	1.0	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	2.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.2	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.8	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.5	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.8	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.7	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	1.0	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.2	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.5	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.5	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	5.7	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	1.2	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.5	REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.0	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.5	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
0.0	0.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.3	REACTOME TRANSLATION	Genes involved in Translation
0.0	0.4	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions

Results for TBX1

Z-value: 1.57

Motif logo

Transcription factors associated with TBX1

Activity-expression correlation:

Activity profile of TBX1 motif

Sorted Z-values of TBX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP:REACTOME category: